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	vogt-koyanagi-harada disease

Disease ID	307
Disease	vogt-koyanagi-harada disease
Definition	A syndrome characterized by bilateral granulomatous UVEITIS with IRITIS and secondary GLAUCOMA, premature ALOPECIA, symmetrical VITILIGO, poliosis circumscripta (a strand of depigmented hair), HEARING DISORDERS, and meningeal signs (neck stiffness and headache). Examination of the cerebrospinal fluid reveals a pattern consistent with MENINGITIS, ASEPTIC. (Adams et al., Principles of Neurology, 6th ed, p748; Surv Ophthalmol 1995 Jan;39(4):265-292)
Synonym	disease haradas disease, vogt-koyanagi-harada harada disease harada's disease harada's disease (disorder) harada's syndrome syndrome, uveomeningoencephalitic syndrome, vkh syndrome, vkh (vogt koyanagi harada) syndrome, vogt koyanagi harada syndrome, vogt-koyanagi-harada uveo-oto-cutaneous syndrome uveomeningoenceph uveomeningoenceph syndrome uveomeningoencephalitic syndrome uveomeningoencephalitic syndrome [disease/finding] uveomeningoencephalitides uveomeningoencephalitis vkh (vogt koyanagi harada) syndrome vkh - vogt-koyanagi-harada syndrome vkh syndrome vkh syndrome (vogt koyanagi harada) vogt koyanagi harada dis vogt koyanagi harada disease vogt koyanagi harada syndrome vogt's disease vogt-koyanagi syndrome vogt-koyanagi syndrome (disorder) vogt-koyanagi-harada disease (disorder) vogt-koyanagi-harada syndrome
Orphanet	ORPHANET:3437
DOID	DOID:12297
UMLS	C0042170
MeSH	D014607
SNOMED-CT	SNOMEDCT_US_2016_09_01:193497004
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:19) C0033860 \| psoriasis \| 2 C0042164 \| uveitis \| 2 C0035305 \| retinal detachment \| 2 C0002170 \| alopecia \| 2 C0006111 \| brain disease \| 1 C0004943 \| behcet disease \| 1 C0032460 \| polycystic ovary \| 1 C0154946 \| acute angle closure glaucoma \| 1 C0456909 \| vision loss \| 1 C0155357 \| posterior scleritis \| 1 C0086543 \| cataract \| 1 C0024441 \| macular hole \| 1 C0026975 \| myelitis \| 1 C0017605 \| angle closure glaucoma \| 1 C0037274 \| dermatosis \| 1 C0003873 \| rheumatoid arthritis \| 1 C0003864 \| arthritis \| 1 C0032460 \| polycystic ovary syndrome \| 1 C0018784 \| sensorineural hearing loss \| 1
Curated Gene	Entrez_id \| Symbol \| Resource(Total Genes:2) 3440 \| IFNA2 \| CTD_human 149233 \| IL23R \| GWASCAT
Inferring Gene	Entrez_id \| Symbol \| Resource(Total Genes:32) 6347 \| CCL2 \| CIPHER 1493 \| CTLA4 \| CIPHER 115352 \| FCRL3 \| CIPHER 3105 \| HLA-A \| CIPHER 3106 \| HLA-B \| CIPHER 3107 \| HLA-C \| CIPHER 3122 \| HLA-DRA \| CIPHER 3123 \| HLA-DRB1 \| CIPHER 3458 \| IFNG \| CIPHER 149233 \| IL23R \| CIPHER 3802 \| KIR2DL1 \| CIPHER 3803 \| KIR2DL2 \| CIPHER 3804 \| KIR2DL3 \| CIPHER 3805 \| KIR2DL4 \| CIPHER 57292 \| KIR2DL5A \| CIPHER 554300 \| KIR2DP1 \| CIPHER 3806 \| KIR2DS1 \| CIPHER 100132285 \| KIR2DS2 \| CIPHER 3808 \| KIR2DS3 \| CIPHER 3809 \| KIR2DS4 \| CIPHER 3810 \| KIR2DS5 \| CIPHER 3811 \| KIR3DL1 \| CIPHER 3812 \| KIR3DL2 \| CIPHER 115653 \| KIR3DL3 \| CIPHER 548594 \| KIR3DP1 \| CIPHER 3813 \| KIR3DS1 \| CIPHER 5133 \| PDCD1 \| CIPHER 26191 \| PTPN22 \| CIPHER 387082 \| SUMO4 \| CIPHER 3117 \| HLA-DQA1 \| CIPHER 3119 \| HLA-DQB1 \| CIPHER 3440 \| IFNA2 \| CTD_human
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:53) 84890 \| ADO \| 1.835 \| DISEASES 400757 \| C1orf141 \| 4.402 \| DISEASES 722 \| C4BPA \| 2.037 \| DISEASES 958 \| CD40 \| 1.176 \| DISEASES 959 \| CD40LG \| 1.087 \| DISEASES 942 \| CD86 \| 1.154 \| DISEASES 629 \| CFB \| 1.142 \| DISEASES 3426 \| CFI \| 1.489 \| DISEASES 23274 \| CLEC16A \| 1.947 \| DISEASES 1351 \| COX8A \| 1.987 \| DISEASES 1447 \| CSN2 \| 1.461 \| DISEASES 4283 \| CXCL9 \| 1.484 \| DISEASES 1908 \| EDN3 \| 1.002 \| DISEASES 356 \| FASLG \| 1.744 \| DISEASES 9873 \| FCHSD2 \| 2.824 \| DISEASES 11116 \| FGFR1OP \| 3.105 \| DISEASES 50943 \| FOXP3 \| 1.48 \| DISEASES 2625 \| GATA3 \| 1.402 \| DISEASES 3105 \| HLA-A \| 2.985 \| DISEASES 3106 \| HLA-B \| 2.853 \| DISEASES 3107 \| HLA-C \| 1.033 \| DISEASES 3115 \| HLA-DPB1 \| 1.117 \| DISEASES 3117 \| HLA-DQA1 \| 2.739 \| DISEASES 3118 \| HLA-DQA2 \| 1.441 \| DISEASES 3119 \| HLA-DQB1 \| 2.52 \| DISEASES 3120 \| HLA-DQB2 \| 2.634 \| DISEASES 3123 \| HLA-DRB1 \| 3.363 \| DISEASES 3127 \| HLA-DRB5 \| 2.217 \| DISEASES 3620 \| IDO1 \| 1.226 \| DISEASES 3440 \| IFNA2 \| 1.216 \| DISEASES 3586 \| IL10 \| 1.272 \| DISEASES 3605 \| IL17A \| 2.712 \| DISEASES 112744 \| IL17F \| 1.41 \| DISEASES 149233 \| IL23R \| 2.236 \| DISEASES 3824 \| KLRD1 \| 1.298 \| DISEASES 22861 \| NLRP1 \| 1.664 \| DISEASES 4942 \| OAT \| 1.076 \| DISEASES 10215 \| OLIG2 \| 1.26 \| DISEASES 143 \| PARP4 \| 1.128 \| DISEASES 5133 \| PDCD1 \| 1.148 \| DISEASES 6490 \| PMEL \| 2.33 \| DISEASES 11168 \| PSIP1 \| 1.807 \| DISEASES 26191 \| PTPN22 \| 1.972 \| DISEASES 6097 \| RORC \| 2.031 \| DISEASES 6295 \| SAG \| 2.783 \| DISEASES 55315 \| SLC29A3 \| 2.586 \| DISEASES 6775 \| STAT4 \| 1.097 \| DISEASES 7096 \| TLR1 \| 1.152 \| DISEASES 10333 \| TLR6 \| 1.485 \| DISEASES 7124 \| TNF \| 1.393 \| DISEASES 10758 \| TRAF3IP2 \| 2.073 \| DISEASES 7306 \| TYRP1 \| 1.805 \| DISEASES 22891 \| ZNF365 \| 2.926 \| DISEASES
Locus	Symbol \| Locus(Total Locus:2) FAS \| 10q23.31 PTPN22 \| 1p13.2

Disease ID	307
Disease	vogt-koyanagi-harada disease
Integrated Phenotype	HPO \| Name(Total Integrated Phenotypes:14) HP:0002216 \| Premature graying of hair HP:0000407 \| Sensorineural hearing impairment HP:0000505 \| Visual impairment HP:0000518 \| Cataract HP:0002290 \| Poliosis HP:0001045 \| Vitiligo HP:0000541 \| Retinal detachment HP:0001053 \| Hypopigmented skin patches HP:0002209 \| Sparse scalp hair HP:0004322 \| Short stature HP:0000499 \| Abnormality of the eyelashes HP:0100543 \| Cognitive impairment HP:0000501 \| Glaucoma HP:0000534 \| Abnormality of the eyebrow
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:19) HP:0000541 \| Detached retina \| 2 HP:0003765 \| Psoriasis \| 2 HP:0001596 \| Hair loss \| 2 HP:0000554 \| Uveitis \| 2 HP:0002094 \| Dyspnea \| 1 HP:0001298 \| Encephalopathy \| 1 HP:0001369 \| Arthritis \| 1 HP:0011508 \| Macular hole \| 1 HP:0001370 \| Rheumatoid arthritis \| 1 HP:0000572 \| Visual loss \| 1 HP:0012074 \| Adie pupil \| 1 HP:0000407 \| sensorineural hearing loss \| 1 HP:0012231 \| Exudative retinal detachment \| 1 HP:0001123 \| Partial loss of field of vision \| 1 HP:0012486 \| Inflammation of spinal cord \| 1 HP:0000518 \| Cataract \| 1 HP:0000969 \| Dropsy \| 1 HP:0001287 \| Meningitis \| 1 HP:0000147 \| Sclerocystic ovaries \| 1

Disease ID	307
Disease	vogt-koyanagi-harada disease
Manually Symptom	UMLS \| Name(Total Manually Symptoms:12) C1963229 \| retinal detachment C0751711 \| anterior ischemic optic neuropathy C0521683 \| chorioretinal atrophy C0344296 \| annular choroidal detachment C0271650 \| glucose intolerance C0154946 \| acute angle-closure glaucoma C0042900 \| vitiligo C0041834 \| erythema C0035305 \| retinal detachments C0024441 \| macular hole C0022890 \| inner ear disease C0002170 \| alopecia
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:4) C0002170 \| alopecia \| 2 C0035305 \| retinal detachment \| 2 C0024441 \| macular hole \| 1 C0263361 \| psoriasis vulgaris \| 1

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

Text Mining Genotype(Total Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:21)
snpId	pubmedId	geneId	geneSymbol	diseaseId	sourceId	sentence	score	Year	geneSymbol_dbSNP	CHROMOSOME	POS	REF	ALT
rs117633859	25108386	84890	ADO	umls:C0042170	BeFree	We identified three loci associated with VKH syndrome susceptibility (IL23R-C1orf141, rs117633859, P(combined) = 3.42 × 10(-21), odds ratio (OR) = 1.82; ADO-ZNF365-EGR2, rs442309, P(combined) = 2.97 × 10(-11), OR = 1.37; and HLA-DRB1/DQA1, rs3021304, P(combined) = 1.26 × 10(-118), OR = 2.97).	0.000271442	2014	IL23R	1	67162145	A	G
rs117633859	25108386	400757	C1orf141	umls:C0042170	BeFree	We identified three loci associated with VKH syndrome susceptibility (IL23R-C1orf141, rs117633859, P(combined) = 3.42 × 10(-21), odds ratio (OR) = 1.82; ADO-ZNF365-EGR2, rs442309, P(combined) = 2.97 × 10(-11), OR = 1.37; and HLA-DRB1/DQA1, rs3021304, P(combined) = 1.26 × 10(-118), OR = 2.97).	0.000271442	2014	IL23R	1	67162145	A	G
rs117633859	25108386	3123	HLA-DRB1	umls:C0042170	BeFree	We identified three loci associated with VKH syndrome susceptibility (IL23R-C1orf141, rs117633859, P(combined) = 3.42 × 10(-21), odds ratio (OR) = 1.82; ADO-ZNF365-EGR2, rs442309, P(combined) = 2.97 × 10(-11), OR = 1.37; and HLA-DRB1/DQA1, rs3021304, P(combined) = 1.26 × 10(-118), OR = 2.97).	0.020455286	2014	IL23R	1	67162145	A	G
rs117633859	25108386	1959	EGR2	umls:C0042170	BeFree	We identified three loci associated with VKH syndrome susceptibility (IL23R-C1orf141, rs117633859, P(combined) = 3.42 × 10(-21), odds ratio (OR) = 1.82; ADO-ZNF365-EGR2, rs442309, P(combined) = 2.97 × 10(-11), OR = 1.37; and HLA-DRB1/DQA1, rs3021304, P(combined) = 1.26 × 10(-118), OR = 2.97).	0.000271442	2014	IL23R	1	67162145	A	G
rs117633859	25108386	149233	IL23R	umls:C0042170	GWASCAT	We identified three loci associated with VKH syndrome susceptibility (IL23R-C1orf141, rs117633859, P(combined) = 3.42 × 10(-21), odds ratio (OR) = 1.82; ADO-ZNF365-EGR2, rs442309, P(combined) = 2.97 × 10(-11), OR = 1.37; and HLA-DRB1/DQA1, rs3021304, P(combined) = 1.26 × 10(-118), OR = 2.97).	0.123452799	2014	IL23R	1	67162145	A	G
rs117633859	25108386	22891	ZNF365	umls:C0042170	BeFree	We identified three loci associated with VKH syndrome susceptibility (IL23R-C1orf141, rs117633859, P(combined) = 3.42 × 10(-21), odds ratio (OR) = 1.82; ADO-ZNF365-EGR2, rs442309, P(combined) = 2.97 × 10(-11), OR = 1.37; and HLA-DRB1/DQA1, rs3021304, P(combined) = 1.26 × 10(-118), OR = 2.97).	0.000271442	2014	IL23R	1	67162145	A	G
rs117633859	25108386	149233	IL23R	umls:C0042170	BeFree	We identified three loci associated with VKH syndrome susceptibility (IL23R-C1orf141, rs117633859, P(combined) = 3.42 × 10(-21), odds ratio (OR) = 1.82; ADO-ZNF365-EGR2, rs442309, P(combined) = 2.97 × 10(-11), OR = 1.37; and HLA-DRB1/DQA1, rs3021304, P(combined) = 1.26 × 10(-118), OR = 2.97).	0.123452799	2014	IL23R	1	67162145	A	G
rs231775	18282809	348120	LINC01193	umls:C0042170	BeFree	In this study, we investigated the association of CTLA-4 gene polymorphisms (- 1661A/G; - 318C/T; + 49G/A, and CT60) with Vogt-Koyanagi-Harada (VKH) syndrome in Chinese Han patients and normal controls.	0.000271442	2008	CTLA4	2	203867991	A	G,T
rs3021304	25108386	1959	EGR2	umls:C0042170	BeFree	We identified three loci associated with VKH syndrome susceptibility (IL23R-C1orf141, rs117633859, P(combined) = 3.42 × 10(-21), odds ratio (OR) = 1.82; ADO-ZNF365-EGR2, rs442309, P(combined) = 2.97 × 10(-11), OR = 1.37; and HLA-DRB1/DQA1, rs3021304, P(combined) = 1.26 × 10(-118), OR = 2.97).	0.000271442	2014	NA	6	32607881	G	C
rs3021304	25108386	149233	IL23R	umls:C0042170	BeFree	We identified three loci associated with VKH syndrome susceptibility (IL23R-C1orf141, rs117633859, P(combined) = 3.42 × 10(-21), odds ratio (OR) = 1.82; ADO-ZNF365-EGR2, rs442309, P(combined) = 2.97 × 10(-11), OR = 1.37; and HLA-DRB1/DQA1, rs3021304, P(combined) = 1.26 × 10(-118), OR = 2.97).	0.123452799	2014	NA	6	32607881	G	C
rs3021304	25108386	84890	ADO	umls:C0042170	BeFree	We identified three loci associated with VKH syndrome susceptibility (IL23R-C1orf141, rs117633859, P(combined) = 3.42 × 10(-21), odds ratio (OR) = 1.82; ADO-ZNF365-EGR2, rs442309, P(combined) = 2.97 × 10(-11), OR = 1.37; and HLA-DRB1/DQA1, rs3021304, P(combined) = 1.26 × 10(-118), OR = 2.97).	0.000271442	2014	NA	6	32607881	G	C
rs3021304	25108386	400757	C1orf141	umls:C0042170	BeFree	We identified three loci associated with VKH syndrome susceptibility (IL23R-C1orf141, rs117633859, P(combined) = 3.42 × 10(-21), odds ratio (OR) = 1.82; ADO-ZNF365-EGR2, rs442309, P(combined) = 2.97 × 10(-11), OR = 1.37; and HLA-DRB1/DQA1, rs3021304, P(combined) = 1.26 × 10(-118), OR = 2.97).	0.000271442	2014	NA	6	32607881	G	C
rs3021304	25108386	3123	HLA-DRB1	umls:C0042170	BeFree	We identified three loci associated with VKH syndrome susceptibility (IL23R-C1orf141, rs117633859, P(combined) = 3.42 × 10(-21), odds ratio (OR) = 1.82; ADO-ZNF365-EGR2, rs442309, P(combined) = 2.97 × 10(-11), OR = 1.37; and HLA-DRB1/DQA1, rs3021304, P(combined) = 1.26 × 10(-118), OR = 2.97).	0.020455286	2014	NA	6	32607881	G	C
rs3021304	25108386	22891	ZNF365	umls:C0042170	BeFree	We identified three loci associated with VKH syndrome susceptibility (IL23R-C1orf141, rs117633859, P(combined) = 3.42 × 10(-21), odds ratio (OR) = 1.82; ADO-ZNF365-EGR2, rs442309, P(combined) = 2.97 × 10(-11), OR = 1.37; and HLA-DRB1/DQA1, rs3021304, P(combined) = 1.26 × 10(-118), OR = 2.97).	0.000271442	2014	NA	6	32607881	G	C
rs442309	25108386	84890	ADO	umls:C0042170	BeFree	We identified three loci associated with VKH syndrome susceptibility (IL23R-C1orf141, rs117633859, P(combined) = 3.42 × 10(-21), odds ratio (OR) = 1.82; ADO-ZNF365-EGR2, rs442309, P(combined) = 2.97 × 10(-11), OR = 1.37; and HLA-DRB1/DQA1, rs3021304, P(combined) = 1.26 × 10(-118), OR = 2.97).	0.000271442	2014	NA	10	62730735	C	T
rs442309	25108386	1959	EGR2	umls:C0042170	BeFree	We identified three loci associated with VKH syndrome susceptibility (IL23R-C1orf141, rs117633859, P(combined) = 3.42 × 10(-21), odds ratio (OR) = 1.82; ADO-ZNF365-EGR2, rs442309, P(combined) = 2.97 × 10(-11), OR = 1.37; and HLA-DRB1/DQA1, rs3021304, P(combined) = 1.26 × 10(-118), OR = 2.97).	0.000271442	2014	NA	10	62730735	C	T
rs442309	25108386	3123	HLA-DRB1	umls:C0042170	BeFree	We identified three loci associated with VKH syndrome susceptibility (IL23R-C1orf141, rs117633859, P(combined) = 3.42 × 10(-21), odds ratio (OR) = 1.82; ADO-ZNF365-EGR2, rs442309, P(combined) = 2.97 × 10(-11), OR = 1.37; and HLA-DRB1/DQA1, rs3021304, P(combined) = 1.26 × 10(-118), OR = 2.97).	0.020455286	2014	NA	10	62730735	C	T
rs442309	25108386	22891	ZNF365	umls:C0042170	BeFree	We identified three loci associated with VKH syndrome susceptibility (IL23R-C1orf141, rs117633859, P(combined) = 3.42 × 10(-21), odds ratio (OR) = 1.82; ADO-ZNF365-EGR2, rs442309, P(combined) = 2.97 × 10(-11), OR = 1.37; and HLA-DRB1/DQA1, rs3021304, P(combined) = 1.26 × 10(-118), OR = 2.97).	0.000271442	2014	NA	10	62730735	C	T
rs442309	25108386	149233	IL23R	umls:C0042170	BeFree	We identified three loci associated with VKH syndrome susceptibility (IL23R-C1orf141, rs117633859, P(combined) = 3.42 × 10(-21), odds ratio (OR) = 1.82; ADO-ZNF365-EGR2, rs442309, P(combined) = 2.97 × 10(-11), OR = 1.37; and HLA-DRB1/DQA1, rs3021304, P(combined) = 1.26 × 10(-118), OR = 2.97).	0.123452799	2014	NA	10	62730735	C	T
rs442309	25108386	400757	C1orf141	umls:C0042170	BeFree	We identified three loci associated with VKH syndrome susceptibility (IL23R-C1orf141, rs117633859, P(combined) = 3.42 × 10(-21), odds ratio (OR) = 1.82; ADO-ZNF365-EGR2, rs442309, P(combined) = 2.97 × 10(-11), OR = 1.37; and HLA-DRB1/DQA1, rs3021304, P(combined) = 1.26 × 10(-118), OR = 2.97).	0.000271442	2014	NA	10	62730735	C	T
rs763780	20620187	112744	IL17F	umls:C0042170	BeFree	The C allele and TT genotype of rs763780 in the IL-17F gene appear to be associated with protection and susceptibility to VKH syndrome.	0.000542884	2010	IL17F;LOC105375088	6	52236941	T	C

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)

Mapped by lexical matching(Total Items:7)
HP ID	HP Name	MP ID	MP Name	Annotation
HP:0002216	Premature graying of hair	MP:0009657	failure of chorioallantoic fusion	failure to initiate and/or complete the formation of a highly vascularized extra-embryonic fetal membrane by fusion of the chorion and allantois
HP:0000534	Abnormality of the eyebrow	MP:0010732	abnormal node of Ranvier morphology	any structural anomaly of the short unmyelinated segments of an axon between myelinated segments, where voltage gated channels accumulate and regenerate an action potential as it is conducted along the axon
HP:0000407	Sensorineural hearing impairment	MP:0006330	syndromic hearing impairment	hearing impairment that is usually associated with malformations of the external ear and other inherited signs and symptoms
HP:0000541	Retinal detachment	MP:0003099	retinal detachment	detachment of the retina from the underlying inner wall of the eye, often from tension of the vitreous; may occur with aging or as a result of trauma
HP:0001053	Hypopigmented skin patches	MP:0004947	skin inflammation	local accumulation of fluid, plasma proteins, and leukocytes in the skin
HP:0002209	Sparse scalp hair	MP:0011195	increased hair follicle apoptosis	greater than expected levels of programmed cell death of cells in the epidermis from which the hair shaft develops
HP:0000499	Abnormality of the eyelashes	MP:0012069	abnormal horizontal basal cell of olfactory epithelium morphology	any structural anomaly of the flat or angular epithelial cell with condensed nuclei and darkly staining cytoplasm containing numerous intermediate filaments inserted into desmosomes contacting surrounding supporting cells, that lie in contact with the bas

Mapped by homologous gene(Total Items:13)
HP ID	HP Name	MP ID	MP Name	Annotation
HP:0100543	Cognitive impairment	MP:0020316	decreased vascular endothelial cell proliferation	decrease in the expansion rate of any vascular endothelial cell population by cell division
HP:0000407	Sensorineural hearing impairment	MP:3000003	abnormal Ebner's gland morphology	any structural anomaly of the serous salivary glands which reside adjacent to the moats surrounding the circumvallate and foliate papillae just anterior to the posterior third of the tongue, anterior to the terminal sulcus; these exocrine glands secrete l
HP:0001053	Hypopigmented skin patches	MP:0014164	abnormal ciliary process morphology	any structural anomaly of any of the pigmented processes that radiate from the ciliary muscle and give attachments to ligaments supporting the lens of the eye; these processes increase in thickness as they advance from the orbiculus ciliaris to the exter
HP:0001045	Vitiligo	MP:0020220	decreased tear production	decreased production of the amount of fluid produced in the eye
HP:0000534	Abnormality of the eyebrow	MP:0020137	decreased bone mineralization	decrease in the rate at which minerals are deposited into bone
HP:0000518	Cataract	MP:3000003	abnormal Ebner's gland morphology	any structural anomaly of the serous salivary glands which reside adjacent to the moats surrounding the circumvallate and foliate papillae just anterior to the posterior third of the tongue, anterior to the terminal sulcus; these exocrine glands secrete l
HP:0000501	Glaucoma	MP:3000003	abnormal Ebner's gland morphology	any structural anomaly of the serous salivary glands which reside adjacent to the moats surrounding the circumvallate and foliate papillae just anterior to the posterior third of the tongue, anterior to the terminal sulcus; these exocrine glands secrete l
HP:0000541	Retinal detachment	MP:0020137	decreased bone mineralization	decrease in the rate at which minerals are deposited into bone
HP:0000505	Visual impairment	MP:3000003	abnormal Ebner's gland morphology	any structural anomaly of the serous salivary glands which reside adjacent to the moats surrounding the circumvallate and foliate papillae just anterior to the posterior third of the tongue, anterior to the terminal sulcus; these exocrine glands secrete l
HP:0000499	Abnormality of the eyelashes	MP:0020137	decreased bone mineralization	decrease in the rate at which minerals are deposited into bone
HP:0004322	Short stature	MP:3000003	abnormal Ebner's gland morphology	any structural anomaly of the serous salivary glands which reside adjacent to the moats surrounding the circumvallate and foliate papillae just anterior to the posterior third of the tongue, anterior to the terminal sulcus; these exocrine glands secrete l
HP:0002216	Premature graying of hair	MP:0014164	abnormal ciliary process morphology	any structural anomaly of any of the pigmented processes that radiate from the ciliary muscle and give attachments to ligaments supporting the lens of the eye; these processes increase in thickness as they advance from the orbiculus ciliaris to the exter
HP:0002209	Sparse scalp hair	MP:0020137	decreased bone mineralization	decrease in the rate at which minerals are deposited into bone

Disease ID	307
Disease	vogt-koyanagi-harada disease
Case	(Waiting for update.)