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	uveitis

Disease ID	405
Disease	uveitis
Definition	Inflammation of part or all of the uvea, the middle (vascular) tunic of the eye, and commonly involving the other tunics (sclera and cornea, and the retina). (Dorland, 27th ed)
Synonym	intraocular inflammation uveitides uveitis (disorder) uveitis [disease/finding] uveitis nos uveitis, nos
Orphanet	ORPHANET:98715
DOID	DOID:13141
UMLS	C0042164
MeSH	D014605
SNOMED-CT	SNOMEDCT_US_2016_09_01:128473001
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:165) C0553662 \| juvenile idiopathic arthritis \| 40 C0003864 \| arthritis \| 28 C0017601 \| glaucoma \| 26 C0086543 \| cataract \| 23 C0004943 \| behcet's disease \| 19 C0036202 \| sarcoidosis \| 17 C0038013 \| ankylosing spondylitis \| 16 C0271051 \| macular edema \| 11 C0004943 \| behcet disease \| 10 C0042384 \| vasculitis \| 10 C0026769 \| multiple sclerosis \| 9 C0152026 \| retinal vasculitis \| 8 C0027707 \| interstitial nephritis \| 8 C0035305 \| retinal detachment \| 7 C0027697 \| nephritis \| 7 C0038012 \| spondylitis \| 7 C0041349 \| tubulointerstitial nephritis \| 7 C0022568 \| keratitis \| 6 C0020538 \| hypertension \| 5 C0152253 \| posterior synechiae \| 5 C0041296 \| tuberculosis \| 5 C0042167 \| posterior uveitis \| 5 C0086543 \| cataracts \| 5 C0042769 \| virus infection \| 4 C0028840 \| ocular hypertension \| 4 C0022073 \| iridocyclitis \| 4 C0456909 \| vision loss \| 4 C0036416 \| scleritis \| 4 C0035333 \| retinitis \| 4 C0042164 \| uveitis \| 4 C0024440 \| cystoid macular edema \| 4 C0456909 \| blindness \| 3 C0040558 \| toxoplasmosis \| 3 C0035435 \| rheumatic disease \| 3 C0039128 \| syphilis \| 3 C0271097 \| usher syndrome \| 3 C0035920 \| rubella \| 3 C0155120 \| band keratopathy \| 3 C0017612 \| open angle glaucoma \| 3 C0019348 \| herpes simplex \| 2 C0008513 \| chorioretinitis \| 2 C0019364 \| herpes zoster ophthalmicus \| 2 C0009324 \| ulcerative colitis \| 2 C0040147 \| thyroiditis \| 2 C0035305 \| retinal detachments \| 2 C0004623 \| bacterial infection \| 2 C0042166 \| intermediate uveitis \| 2 C0011570 \| depression \| 2 C0021053 \| immune disease \| 2 C0040561 \| ocular toxoplasmosis \| 2 C0677607 \| hashimoto's thyroiditis \| 2 C0042170 \| vogt-koyanagi-harada disease \| 2 C0008526 \| choroiditis \| 2 C0003872 \| psoriatic arthritis \| 2 C0949691 \| spondyloarthropathies \| 2 C0011603 \| dermatitis \| 2 C0152257 \| mature cataract \| 2 C0042165 \| anterior uveitis \| 2 C0042164 \| intraocular inflammation \| 2 C0019360 \| herpes zoster \| 2 C0042170 \| harada disease \| 2 C0035435 \| rheumatic diseases \| 2 C0017605 \| angle closure glaucoma \| 2 C0011847 \| diabetes \| 2 C0030343 \| panuveitis \| 2 C0019364 \| zoster ophthalmicus \| 2 C0019360 \| zoster \| 2 C0949690 \| spondyloarthritis \| 2 C0206178 \| cmv retinitis \| 2 C0544008 \| chandler's syndrome \| 1 C0021053 \| immune disorders \| 1 C0007113 \| rectal cancer \| 1 C0022568 \| corneal inflammation \| 1 C0235270 \| keratopathy \| 1 C0004623 \| bacterial infections \| 1 C0022573 \| keratoconjunctivitis \| 1 C0036205 \| lung sarcoidosis \| 1 C0949691 \| spondylarthropathies \| 1 C0014236 \| endophthalmitis \| 1 C0021053 \| immune disorder \| 1 C0032453 \| relapsing polychondritis \| 1 C0015458 \| parry-romberg syndrome \| 1 C0002170 \| alopecia \| 1 C0028817 \| ochronosis \| 1 C0035334 \| retinitis pigmentosa \| 1 C0015624 \| fanconi syndrome \| 1 C0035326 \| retinal vascular occlusion \| 1 C0020581 \| hyphema \| 1 C0029134 \| optic neuritis \| 1 C0042109 \| urticarial \| 1 C0007939 \| syphilitic chancre \| 1 C0206178 \| cytomegalovirus retinitis \| 1 C0019829 \| hodgkin disease \| 1 C0019158 \| hepatitis \| 1 C0019163 \| hepatitis b \| 1 C0009447 \| common variable immunodeficiency \| 1 C0271051 \| macular oedema \| 1 C0271270 \| cogan's syndrome \| 1 C0221023 \| cyclic neutropenia \| 1 C0003864 \| joint inflammation \| 1 C0155223 \| dacryoadenitis \| 1 C0949690 \| spondylarthritis \| 1 C0027947 \| neutropenia \| 1 C0001175 \| acquired immunodeficiency syndrome \| 1 C0027813 \| neuritis \| 1 C0861772 \| metastatic rectal cancer \| 1 C0027121 \| myositis \| 1 C0027538 \| necrobiosis lipoidica \| 1 C0015624 \| fanconi's syndrome \| 1 C0036202 \| sarcoid \| 1 C0029077 \| sympathetic ophthalmia \| 1 C0031154 \| peritonitis \| 1 C0085253 \| adult-onset still's disease \| 1 C0023343 \| leprosy \| 1 C0022408 \| joint disease \| 1 C0025202 \| melanoma \| 1 C0019655 \| histoplasmosis \| 1 C0038379 \| squint \| 1 C0149925 \| small cell lung carcinoma \| 1 C0014121 \| infective endocarditis \| 1 C0155088 \| interstitial keratitis \| 1 C0021053 \| immunologic disease \| 1 C0015230 \| rash \| 1 C0010037 \| corneal edema \| 1 C0012236 \| digeorge syndrome \| 1 C0033860 \| psoriasis \| 1 C0085437 \| bacterial meningitis \| 1 C1861303 \| blau syndrome \| 1 C0684249 \| lung carcinoma \| 1 C0024441 \| macular hole \| 1 C0017661 \| iga nephropathy \| 1 C0085435 \| reactive arthritis \| 1 C0010678 \| cysticercosis \| 1 C0022658 \| renal disease \| 1 C0031069 \| familial mediterranean fever \| 1 C0026896 \| myasthenia gravis \| 1 C0152258 \| hypermature cataract \| 1 C0007939 \| chancre \| 1 C0022081 \| iritis \| 1 C0016782 \| fuchs' heterochromic iridocyclitis \| 1 C0042384 \| angiitis \| 1 C0036205 \| pulmonary sarcoidosis \| 1 C0021053 \| immunologic diseases \| 1 C0241910 \| autoimmune hepatitis \| 1 C0011303 \| demyelinating disease \| 1 C0023364 \| leptospirosis \| 1 C0042900 \| vitiligo \| 1 C0278883 \| metastatic melanoma \| 1 C0007570 \| celiac disease \| 1 C0017601 \| glaucomas \| 1 C0242420 \| retinal edema \| 1 C0006309 \| brucellosis \| 1 C0023467 \| acute myeloid leukemia \| 1 C0017658 \| glomerulonephritis \| 1 C0020550 \| hyperthyroidism \| 1 C0030593 \| pars planitis \| 1 C0553662 \| juvenile arthritis \| 1 C0004153 \| atherosclerosis \| 1 C0206141 \| hypereosinophilic syndrome \| 1 C0030353 \| papilloedema \| 1 C1853959 \| birdshot chorioretinopathy \| 1 C0001175 \| acquired immunodeficiency syndrome (aids) \| 1 C0030354 \| papilloma \| 1 C0949691 \| spondyloarthropathy \| 1 C0022658 \| nephropathy \| 1
Curated Gene	Entrez_id \| Symbol \| Resource(Total Genes:9) 213 \| ALB \| CTD_human 6295 \| SAG \| CTD_human;UniProtKB-KW 1415 \| CRYBB2 \| CTD_human 6648 \| SOD2 \| CTD_human 1409 \| CRYAA \| CTD_human 3313 \| HSPA9 \| CTD_human 5949 \| RBP3 \| CTD_human 5176 \| SERPINF1 \| CTD_human 794 \| CALB2 \| CTD_human
Inferring Gene	Entrez_id \| Symbol \| Resource(Total Genes:23) 6347 \| CCL2 \| CIPHER 6352 \| CCL5 \| CIPHER 729230 \| CCR2 \| CIPHER 1234 \| CCR5 \| CIPHER 3105 \| HLA-A \| CIPHER 3107 \| HLA-C \| CIPHER 3119 \| HLA-DQB1 \| CIPHER 3123 \| HLA-DRB1 \| CIPHER 3458 \| IFNG \| CIPHER 3586 \| IL10 \| CIPHER 4049 \| LTA \| CIPHER 7124 \| TNF \| CIPHER 7132 \| TNFRSF1A \| CIPHER 7133 \| TNFRSF1B \| CIPHER 1415 \| CRYBB2 \| CTD_human 1409 \| CRYAA \| CTD_human 213 \| ALB \| CTD_human 3313 \| HSPA9 \| CTD_human 6295 \| SAG \| CTD_human 5176 \| SERPINF1 \| CTD_human 794 \| CALB2 \| CTD_human 6648 \| SOD2 \| CTD_human 5949 \| RBP3 \| CTD_human
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:154) 441376 \| AARD \| 1.783 \| DISEASES 135 \| ADORA2A \| 1.022 \| DISEASES 140 \| ADORA3 \| 1.213 \| DISEASES 125061 \| AFMID \| 1.475 \| DISEASES 199 \| AIF1 \| 1.336 \| DISEASES 9255 \| AIMP1 \| 2.004 \| DISEASES 361 \| AQP4 \| 1.215 \| DISEASES 567 \| B2M \| 3.031 \| DISEASES 64170 \| CARD9 \| 1.721 \| DISEASES 6364 \| CCL20 \| 1.323 \| DISEASES 388372 \| CCL4L1 \| 1.314 \| DISEASES 9332 \| CD163 \| 1.113 \| DISEASES 930 \| CD19 \| 1.497 \| DISEASES 911 \| CD1C \| 1.251 \| DISEASES 29126 \| CD274 \| 1.618 \| DISEASES 958 \| CD40 \| 1.268 \| DISEASES 959 \| CD40LG \| 4.283 \| DISEASES 960 \| CD44 \| 1.4 \| DISEASES 921 \| CD5 \| 1.303 \| DISEASES 966 \| CD59 \| 1.143 \| DISEASES 942 \| CD86 \| 1.915 \| DISEASES 30850 \| CDR2L \| 1.589 \| DISEASES 629 \| CFB \| 1.397 \| DISEASES 3075 \| CFH \| 1.623 \| DISEASES 3080 \| CFHR2 \| 1.375 \| DISEASES 3426 \| CFI \| 1.347 \| DISEASES 9391 \| CIAO1 \| 1.218 \| DISEASES 1154 \| CISH \| 1.718 \| DISEASES 23601 \| CLEC5A \| 1.216 \| DISEASES 93978 \| CLEC6A \| 1.253 \| DISEASES 23418 \| CRB1 \| 1.867 \| DISEASES 8804 \| CREG1 \| 2.408 \| DISEASES 1415 \| CRYBB2 \| 3.125 \| DISEASES 1524 \| CX3CR1 \| 1.71 \| DISEASES 2919 \| CXCL1 \| 1.821 \| DISEASES 6387 \| CXCL12 \| 1.297 \| DISEASES 4283 \| CXCL9 \| 2.486 \| DISEASES 2833 \| CXCR3 \| 2.429 \| DISEASES 51428 \| DDX41 \| 2.356 \| DISEASES 7913 \| DEK \| 1.782 \| DISEASES 1810 \| DR1 \| 1.086 \| DISEASES 6993 \| DYNLT1 \| 2.005 \| DISEASES 1896 \| EDA \| 3.028 \| DISEASES 953 \| ENTPD1 \| 1.378 \| DISEASES 64167 \| ERAP2 \| 1.534 \| DISEASES 30816 \| ERVW-1 \| 1.275 \| DISEASES 356 \| FASLG \| 1.796 \| DISEASES 121512 \| FGD4 \| 1.031 \| DISEASES 752 \| FMNL1 \| 1.029 \| DISEASES 50943 \| FOXP3 \| 3.462 \| DISEASES 6011 \| GRK1 \| 1.387 \| DISEASES 3005 \| H1F0 \| 1.395 \| DISEASES 26508 \| HEYL \| 1.198 \| DISEASES 3105 \| HLA-A \| 3.303 \| DISEASES 3106 \| HLA-B \| 4.202 \| DISEASES 3107 \| HLA-C \| 1.244 \| DISEASES 3115 \| HLA-DPB1 \| 2.158 \| DISEASES 3117 \| HLA-DQA1 \| 2.349 \| DISEASES 3119 \| HLA-DQB1 \| 1.831 \| DISEASES 3123 \| HLA-DRB1 \| 2.821 \| DISEASES 3329 \| HSPD1 \| 2.134 \| DISEASES 23308 \| ICOSLG \| 2.21 \| DISEASES 3440 \| IFNA2 \| 1.073 \| DISEASES 3456 \| IFNB1 \| 1.778 \| DISEASES 3459 \| IFNGR1 \| 1.002 \| DISEASES 3586 \| IL10 \| 4.557 \| DISEASES 3605 \| IL17A \| 4.794 \| DISEASES 112744 \| IL17F \| 2.622 \| DISEASES 23765 \| IL17RA \| 1.928 \| DISEASES 29949 \| IL19 \| 1.591 \| DISEASES 7850 \| IL1R2 \| 1.15 \| DISEASES 50616 \| IL22 \| 2.373 \| DISEASES 149233 \| IL23R \| 2.918 \| DISEASES 64806 \| IL25 \| 1.463 \| DISEASES 246778 \| IL27 \| 2.24 \| DISEASES 3559 \| IL2RA \| 2.304 \| DISEASES 386653 \| IL31 \| 2.065 \| DISEASES 90865 \| IL33 \| 1.901 \| DISEASES 3652 \| IPP \| 1.576 \| DISEASES 134728 \| IRAK1BP1 \| 1.637 \| DISEASES 51135 \| IRAK4 \| 1.176 \| DISEASES 3683 \| ITGAL \| 1.776 \| DISEASES 3684 \| ITGAM \| 2.233 \| DISEASES 3766 \| KCNJ10 \| 1.38 \| DISEASES 3778 \| KCNMA1 \| 2.185 \| DISEASES 23046 \| KIF21B \| 1.251 \| DISEASES 3811 \| KIR3DL1 \| 1.6 \| DISEASES 3824 \| KLRD1 \| 1.156 \| DISEASES 4049 \| LTA \| 2.074 \| DISEASES 84946 \| LTV1 \| 2.565 \| DISEASES 139599 \| MAGEE2 \| 2.184 \| DISEASES 4155 \| MBP \| 2.735 \| DISEASES 9656 \| MDC1 \| 1.205 \| DISEASES 100507436 \| MICA \| 2.841 \| DISEASES 50488 \| MINK1 \| 2.713 \| DISEASES 4615 \| MYD88 \| 2.132 \| DISEASES 81565 \| NDEL1 \| 3.197 \| DISEASES 114548 \| NLRP3 \| 2.713 \| DISEASES 4843 \| NOS2 \| 1.562 \| DISEASES 4942 \| OAT \| 1.604 \| DISEASES 100506658 \| OCLN \| 1.569 \| DISEASES 54726 \| OTUD4 \| 1.933 \| DISEASES 5132 \| PDC \| 2.717 \| DISEASES 5133 \| PDCD1 \| 1.513 \| DISEASES 80380 \| PDCD1LG2 \| 1.077 \| DISEASES 114770 \| PGLYRP2 \| 1.272 \| DISEASES 57115 \| PGLYRP4 \| 1.567 \| DISEASES 11331 \| PHB2 \| 3.089 \| DISEASES 5251 \| PHEX \| 1.072 \| DISEASES 6490 \| PMEL \| 1.09 \| DISEASES 11168 \| PSIP1 \| 1.995 \| DISEASES 5698 \| PSMB9 \| 2.883 \| DISEASES 100130889 \| PSORS1C3 \| 2.067 \| DISEASES 5743 \| PTGS2 \| 1.936 \| DISEASES 26191 \| PTPN22 \| 1.804 \| DISEASES 5788 \| PTPRC \| 2.023 \| DISEASES 26064 \| RAI14 \| 1.41 \| DISEASES 54476 \| RNF216 \| 1.151 \| DISEASES 6171 \| RPL41 \| 1.047 \| DISEASES 6251 \| RSU1 \| 1.227 \| DISEASES 6288 \| SAA1 \| 1.199 \| DISEASES 6295 \| SAG \| 6.164 \| DISEASES 677767 \| SCARNA7 \| 1.577 \| DISEASES 6401 \| SELE \| 2.149 \| DISEASES 5265 \| SERPINA1 \| 2.504 \| DISEASES 55315 \| SLC29A3 \| 1.951 \| DISEASES 57153 \| SLC44A2 \| 1.195 \| DISEASES 6524 \| SLC5A2 \| 1.017 \| DISEASES 23583 \| SMUG1 \| 1.012 \| DISEASES 8651 \| SOCS1 \| 2.121 \| DISEASES 9021 \| SOCS3 \| 1.964 \| DISEASES 6731 \| SRP72 \| 1.848 \| DISEASES 6772 \| STAT1 \| 1.862 \| DISEASES 6775 \| STAT4 \| 1.589 \| DISEASES 342898 \| SYCN \| 1.056 \| DISEASES 7062 \| TCHH \| 1.302 \| DISEASES 9895 \| TECPR2 \| 1.476 \| DISEASES 7042 \| TGFB2 \| 2.652 \| DISEASES 7096 \| TLR1 \| 1.43 \| DISEASES 7099 \| TLR4 \| 3.201 \| DISEASES 51284 \| TLR7 \| 1.218 \| DISEASES 54106 \| TLR9 \| 1.432 \| DISEASES 7124 \| TNF \| 5.479 \| DISEASES 8784 \| TNFRSF18 \| 1.61 \| DISEASES 7133 \| TNFRSF1B \| 5.061 \| DISEASES 8718 \| TNFRSF25 \| 1.81 \| DISEASES 7293 \| TNFRSF4 \| 2.654 \| DISEASES 56658 \| TRIM39 \| 1.49 \| DISEASES 51393 \| TRPV2 \| 2.353 \| DISEASES 337867 \| UBAC2 \| 1.826 \| DISEASES 7422 \| VEGFA \| 3.236 \| DISEASES 7432 \| VIP \| 1.655 \| DISEASES 5212 \| VIT \| 1.783 \| DISEASES 7710 \| ZNF154 \| 1.62 \| DISEASES
Locus	(Waiting for update.)

Disease ID	405
Disease	uveitis
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:99) HP:0005681 \| Juvenile idiopathic arthritis \| 41 HP:0000518 \| Cataract \| 31 HP:0001369 \| Arthritis \| 30 HP:0000501 \| Glaucoma \| 26 HP:0000572 \| Visual loss \| 14 HP:0002633 \| Vasculitis \| 11 HP:0000969 \| Dropsy \| 11 HP:0012531 \| Pain \| 9 HP:0040049 \| Macular edema \| 9 HP:0001970 \| Interstitial nephritis \| 8 HP:0000123 \| Nephritis \| 7 HP:0000505 \| Poor vision \| 7 HP:0012123 \| Posterior uveitis \| 7 HP:0000541 \| Detached retina \| 6 HP:0002960 \| Autoimmune condition \| 6 HP:0000491 \| Corneal inflammation \| 6 HP:0000822 \| Hypertension \| 5 HP:0000618 \| Blindness \| 5 HP:0011484 \| Posterior synechiae \| 5 HP:0100533 \| Ocular inflammation \| 5 HP:0000554 \| Uveitis \| 4 HP:0100532 \| Scleritis \| 4 HP:0012231 \| Exudative retinal detachment \| 4 HP:0001094 \| Iridocyclitis \| 4 HP:0200026 \| Ocular pain \| 3 HP:0011505 \| Cystoid macular edema \| 3 HP:0007777 \| Chorioretinal scar \| 3 HP:0002721 \| Immunodeficiency \| 3 HP:0100279 \| Ulcerative colitis \| 2 HP:0003765 \| Psoriasis \| 2 HP:0002664 \| Neoplasia \| 2 HP:0000613 \| Extreme light sensitivity \| 2 HP:0000716 \| Depression \| 2 HP:0012121 \| Panuveitis \| 2 HP:0000872 \| Hashimoto's thyroiditis \| 2 HP:0001141 \| Severe visual impairment \| 2 HP:0002829 \| Arthralgias \| 2 HP:0011531 \| Hyalitis \| 2 HP:0002861 \| Melanoma \| 2 HP:0001101 \| Iritis \| 2 HP:0012424 \| Chorioretinitis \| 2 HP:0000585 \| Band keratopathy \| 2 HP:0012124 \| Intermediate uveitis \| 2 HP:0012122 \| Anterior uveitis \| 2 HP:0100646 \| Thyroiditis \| 2 HP:0010885 \| Aseptic necrosis \| 1 HP:0002597 \| Abnormality of blood vessels \| 1 HP:0030652 \| Vitreous haze \| 1 HP:0001045 \| Blotchy loss of skin color \| 1 HP:0004808 \| Acute myelogenous leukemia \| 1 HP:0100832 \| Myiodeopsia \| 1 HP:0008030 \| Retinal arteritis \| 1 HP:0000099 \| Glomerular nephritis \| 1 HP:0000608 \| Macular degeneration \| 1 HP:0003473 \| Fatigable weakness \| 1 HP:0000836 \| Overactive thyroid \| 1 HP:0001134 \| Anterior polar cataract \| 1 HP:0006689 \| Bacterial endocarditis \| 1 HP:0030731 \| Carcinoma \| 1 HP:0000529 \| Slowly progressive visual loss \| 1 HP:0003249 \| Genital ulcers \| 1 HP:0001945 \| Fever \| 1 HP:0100653 \| Optic neuritis \| 1 HP:0001596 \| Hair loss \| 1 HP:0012115 \| Liver inflammation \| 1 HP:0000112 \| Nephropathy \| 1 HP:0000486 \| Squint eyes \| 1 HP:0002608 \| Celiac disease \| 1 HP:0011886 \| Hyphema \| 1 HP:0001096 \| Keratoconjunctivitis \| 1 HP:0010696 \| Polar cataract \| 1 HP:0100614 \| Muscle inflammation \| 1 HP:0001059 \| Pterygium \| 1 HP:0003418 \| Back pain \| 1 HP:0100778 \| Cryoglobulinemia \| 1 HP:0100014 \| Macular pucker \| 1 HP:0004729 \| Acute tubulointerstitial nephritis \| 1 HP:0000519 \| Cataracts, lenticular, bilateral \| 1 HP:0012189 \| Hodgkin disease \| 1 HP:0007902 \| Vitreous hemorrhage \| 1 HP:0012056 \| Cutaneous melanoma \| 1 HP:0002621 \| Atherosclerosis \| 1 HP:0030764 \| Ochronosis \| 1 HP:0000510 \| Retinitis pigmentosa \| 1 HP:0100662 \| Cartilage inflammation \| 1 HP:0009916 \| Asymmetric pupil sizes \| 1 HP:0030838 \| Hip pain \| 1 HP:0030357 \| Small cell lung carcinoma \| 1 HP:0003076 \| Glucosuria \| 1 HP:0012740 \| Papilloma \| 1 HP:0002313 \| Spastic paraparesis \| 1 HP:0012155 \| Reduced corneal sensation \| 1 HP:0001875 \| Neutropenia \| 1 HP:0011508 \| Macular hole \| 1 HP:0012393 \| Allergy \| 1 HP:0000488 \| Noninflammatory retina disease \| 1 HP:0000622 \| Blurred vision \| 1 HP:0000667 \| Phthisis bulbi \| 1 HP:0002586 \| Peritonitis \| 1

Disease ID	405
Disease	uveitis
Manually Symptom	UMLS \| Name(Total Manually Symptoms:74) C2707258 \| infections C2697310 \| sarcoidosis C2678504 \| osteoporosis C2364133 \| infection C2243086 \| basal cell adenocarcinoma C2096315 \| headache C2029884 \| hearing loss C1998028 \| photoreceptor degeneration C1963229 \| retinal detachment C1962986 \| glaucoma C1962983 \| cataract C1843274 \| acute tubulointerstitial nephritis C1611280 \| allergy C1546654 \| granuloma C1417325 \| multiple sclerosis C1373218 \| immunosuppression C1363843 \| retinal vascular changes C1306068 \| secondary cataract C1302690 \| retinal thickening C1096278 \| anterior chamber inflammation C0852949 \| arteriopathy C0796095 \| c syndrome C0730362 \| maculopathy C0730345 \| microalbuminuria C0729552 \| genital infection C0700109 \| rigidity C0595921 \| intraocular pressure C0456909 \| blindness C0442893 \| systemic disease C0426768 \| o sign C0343029 \| tuberculids C0271215 \| legal blindness C0271051 \| macular oedema C0271051 \| macular edema C0268780 \| idiopathic acute interstitial nephritis C0241910 \| autoimmune hepatitis C0238036 \| bronchocentric granulomatosis C0221262 \| poliosis C0162835 \| depigmentation C0155288 \| papilledema C0155118 \| corneal degeneration C0152259 \| complicated cataract C0152259 \| cataracta complicata C0152253 \| posterior synechiae C0149937 \| acute interstitial nephritis C0149893 \| secondary glaucoma C0086543 \| cataracts C0042164 \| intraocular inflammation C0041349 \| tubulointerstitial nephritis C0041296 \| tuberculosis C0040558 \| toxoplasmosis C0040553 \| toxocariasis C0036205 \| pulmonary sarcoidosis C0035321 \| retinal tears C0035321 \| retinal tear C0035304 \| retinal degeneration C0028840 \| ocular hypertension C0027707 \| interstitial nephritis C0027697 \| nephritis C0024440 \| cystoid macular oedema C0024440 \| cystoid macular edema C0023316 \| lens subluxation C0022568 \| keratitis C0021053 \| immunity disorders C0020097 \| htlv-i C0019625 \| rosai-dorfman disease C0017609 \| neovascular glaucoma C0017601 \| glaucomas C0015397 \| eye disease C0014070 \| encephalomyelitis C0010037 \| corneal edema C0006035 \| borreliosis C0004364 \| autoimmune disease C0003864 \| arthritis
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:41) C0003864 \| arthritis \| 30 C0086543 \| cataract \| 26 C0017601 \| glaucoma \| 26 C0036202 \| sarcoidosis \| 21 C0149893 \| secondary glaucoma \| 14 C0442893 \| systemic disease \| 12 C0026769 \| multiple sclerosis \| 10 C0021888 \| intraocular pressure \| 9 C0009450 \| infection \| 8 C0027707 \| interstitial nephritis \| 8 C0271051 \| macular edema \| 8 C0041349 \| tubulointerstitial nephritis \| 7 C0027697 \| nephritis \| 7 C0041296 \| tuberculosis \| 6 C0021311 \| infections \| 6 C0035305 \| retinal detachment \| 5 C0152253 \| posterior synechiae \| 5 C0022568 \| keratitis \| 5 C0426768 \| o sign \| 5 C0040558 \| toxoplasmosis \| 4 C0456909 \| blindness \| 4 C0086543 \| cataracts \| 4 C0024440 \| cystoid macular edema \| 3 C0028840 \| ocular hypertension \| 3 C0004364 \| autoimmune disease \| 3 C0042164 \| intraocular inflammation \| 3 C0796095 \| c syndrome \| 2 C1096278 \| anterior chamber inflammation \| 2 C0152259 \| complicated cataract \| 2 C0017601 \| glaucomas \| 1 C0162835 \| depigmentation \| 1 C0241910 \| autoimmune hepatitis \| 1 C0010037 \| corneal edema \| 1 C0021079 \| immunosuppression \| 1 C0002111 \| allergy \| 1 C0036205 \| pulmonary sarcoidosis \| 1 C0018188 \| granuloma \| 1 C0271051 \| macular oedema \| 1 C0149937 \| acute interstitial nephritis \| 1 C0730362 \| maculopathy \| 1 C1843274 \| acute tubulointerstitial nephritis \| 1

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

Text Mining Genotype(Total Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:14)
snpId	pubmedId	geneId	geneSymbol	diseaseId	sourceId	sentence	score	Year	geneSymbol_dbSNP	CHROMOSOME	POS	REF	ALT
rs1061170	23497844	3075	CFH	umls:C0042164	BeFree	Association of complement factor H tyrosine 402 histidine genotype with posterior involvement in sarcoid-related uveitis.	0.000542884	2013	CFH	1	196690107	C	T
rs1065489	23966370	3075	CFH	umls:C0042164	BeFree	This study revealed an association of CFH-rs1065489 with AU as well as uveitis recurrence frequency.	0.000542884	2013	CFH	1	196740644	G	T
rs10954213	24116155	3663	IRF5	umls:C0042164	BeFree	Consistently, the subphenotype analysis accordingly with the presence/absence of this clinical condition also reached statistical significance (rs2004640: P=0.037, OR=0.69, CI 95%=0.48-0.98; rs10954213: P=0.030, OR=0.67, CI 95%=0.47-0.96), thus suggesting that both IRF5 genetic variants are specifically associated with the lack of macular edema in uveitis patients.	0.000271442	2013	IRF5	7	128949373	G	A
rs17095830	23308121	8213	BAS	umls:C0042164	BeFree	The correlation between genetic polymorphisms, AS activity indexes, (namely, BASDAI, BASFI and BAS-G) and AS complications (uveitis and inflammatory bowel disease) were tested using the markers, rs4552569 and rs17095830.	0.000271442	2013	ANO6;LOC105369743	12	45381125	A	G
rs1799969	20445114	3383	ICAM1	umls:C0042164	BeFree	G/R 241 polymorphism of intercellular adhesion molecule 1 (ICAM-1) is associated with Fuchs uveitis.	0.080542884	2010	ICAM1;LOC105372272	19	10284116	G	A
rs2004640	24116155	3663	IRF5	umls:C0042164	BeFree	Consistently, the subphenotype analysis accordingly with the presence/absence of this clinical condition also reached statistical significance (rs2004640: P=0.037, OR=0.69, CI 95%=0.48-0.98; rs10954213: P=0.030, OR=0.67, CI 95%=0.47-0.96), thus suggesting that both IRF5 genetic variants are specifically associated with the lack of macular edema in uveitis patients.	0.000271442	2013	IRF5	7	128938247	T	G
rs2075800	17591867	3305	HSPA1L	umls:C0042164	BeFree	A strong association was found between HSP-70/Hom rs2075800 G and uveitis in patients with sarcoidosis.	0.000271442	2007	HSPA1L	6	31810169	C	T
rs2222202	20335604	3586	IL10	umls:C0042164	BeFree	The results demonstrate that uveitis is associated with three haplotype-tagging SNPs (htSNPs) in the IL10 gene: htSNP2 (rs6703630), htSNP5 (rs2222202), and htSNP6 (rs3024490).	0.007177041	2010	IL10	1	206772036	G	A
rs3024490	20335604	3586	IL10	umls:C0042164	BeFree	The results demonstrate that uveitis is associated with three haplotype-tagging SNPs (htSNPs) in the IL10 gene: htSNP2 (rs6703630), htSNP5 (rs2222202), and htSNP6 (rs3024490).	0.007177041	2010	IL10	1	206771966	A	C
rs361525	20335604	7124	TNF	umls:C0042164	GAD	[The role of 12 polymorphisms spanning the TNFA and IL10 genomic regions was investigated in 192 uveitis patients and 92 population control subjects from four regional centers in the United Kingdom and Republic of Ireland.]	0.092453989	2010	TNF	6	31575324	G	A
rs4552569	23308121	8213	BAS	umls:C0042164	BeFree	The correlation between genetic polymorphisms, AS activity indexes, (namely, BASDAI, BASFI and BAS-G) and AS complications (uveitis and inflammatory bowel disease) were tested using the markers, rs4552569 and rs17095830.	0.000271442	2013	NA	5	83877774	C	T
rs6703630	20335604	3586	IL10	umls:C0042164	BeFree	The results demonstrate that uveitis is associated with three haplotype-tagging SNPs (htSNPs) in the IL10 gene: htSNP2 (rs6703630), htSNP5 (rs2222202), and htSNP6 (rs3024490).	0.007177041	2010	IL10	1	206775294	C	T
rs6703630	20335604	3586	IL10	umls:C0042164	GAD	[The results demonstrate that uveitis is associated with three haplotype-tagging SNPs (htSNPs) in the IL10 gene: htSNP2 (rs6703630), htSNP5 (rs2222202), and htSNP6 (rs3024490).]	0.007177041	2010	IL10	1	206775294	C	T
rs909253	20335604	4049	LTA	umls:C0042164	GAD	[Since these variants are implicated in the susceptibility and severity of several immunologic disorders, the results support the hypothesis that common genetic determinants influence shared mechanisms of autoimmunity.]	0.009468128	2010	LTA;LOC100287329	6	31572536	A	G

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:2)
CHR	POS	SNPID	REF	ALT	ORI_SNPID	PMID	P_VALUE	P_VALUE_TEXT	OR/BETA	CI95_TEXT	GWAS_INITIAL_SAMPLE_SIZE	SUB_POPULATION	SUPER_POPULATION	GWAS_TRAIT	HPO_ID	HPO_TERM	DO_ID	DO_TERM	MESH_ID	MESH_TERM	EFO_ID	EFO_TERM	DOLITE_TERM	RISK_ALLELE	PUBLICATION_TYPE	AA	GENE_SYMBOL	TYPE	REFGENE
5	96290647	rs7705093	C	T	rs7705093	24957906	2.00E-09	NA	2.2	[1.70-2.90]	117 European ancestry cases; 693 European ancestry controls	European(810)	ALL(810)	EUR(810)	ALL(810)	Birdshot chorioretinopathy	HPOID:0000554	Uveitis	DOID:13141	uveitis	NA	NA	NA	NA	NA	rs7705093-T	Research Support, N.I.H., Extramural	C	LNPEP
14	102845867	rs150571175	G	A	rs150571175	24957906	2.00E-07	NA	4.6	[2.60-8.30]	117 European ancestry cases; 693 European ancestry controls	European(810)	ALL(810)	EUR(810)	ALL(810)	Birdshot chorioretinopathy	HPOID:0000554	Uveitis	DOID:13141	uveitis	NA	NA	NA	NA	NA	rs150571175-A	Research Support, N.I.H., Extramural	NA	TECPR2

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Disease ID	405
Disease	uveitis
Case	(Waiting for update.)

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