eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| thyroid lymphoma | ||||
| Disease ID | 1867 |
|---|---|
| Disease | thyroid lymphoma |
| Definition | A lymphoma primarily involving the thyroid gland. |
| Synonym | lymphoma of the thyroid lymphoma of the thyroid gland lymphoma of thyroid lymphoma of thyroid gland primary thyroid gland lymphoma thyroid gland lymphoma |
| Orphanet | |
| DOID | |
| UMLS | C1336753 |
| Comorbidity | UMLS | Disease | Sentences' Count(Total Sentences:14) C0677607 | hashimoto's thyroiditis | 9 C0040147 | thyroiditis | 7 C0024299 | malignant lymphoma | 5 C0549473 | thyroid carcinoma | 2 C0007115 | thyroid ca | 2 C0242647 | malt lymphoma | 2 C0079774 | peripheral t-cell lymphoma | 1 C0040137 | thyroid nodule | 1 C0677607 | lymphocytic thyroiditis | 1 C0040137 | thyroid nodules | 1 C0079731 | b-cell lymphoma | 1 C0006413 | burkitt's lymphoma | 1 C0238463 | papillary thyroid carcinoma | 1 C0024299 | lymphoma | 1 |
| Curated Gene | (Waiting for update.) |
| Inferring Gene | (Waiting for update.) |
| Text Mined Gene | Entrez_id | Symbol | Score | Resource(Total Genes:21) 796 | CALCA | 1.288 | DISEASES 921 | CD5 | 1.573 | DISEASES 995 | CDC25C | 1.792 | DISEASES 983 | CDK1 | 2.232 | DISEASES 10987 | COPS5 | 2.445 | DISEASES 4283 | CXCL9 | 1.199 | DISEASES 2833 | CXCR3 | 1.195 | DISEASES 1847 | DUSP5 | 2.055 | DISEASES 1879 | EBF1 | 2.275 | DISEASES 253738 | EBF3 | 3.247 | DISEASES 2261 | FGFR3 | 1.195 | DISEASES 2316 | FLNA | 2.213 | DISEASES 100423062 | IGLL5 | 2.284 | DISEASES 4311 | MME | 1.388 | DISEASES 5079 | PAX5 | 1.556 | DISEASES 8301 | PICALM | 5.571 | DISEASES 5406 | PNLIP | 2.27 | DISEASES 5788 | PTPRC | 1.999 | DISEASES 399 | RHOH | 3.028 | DISEASES 23583 | SMUG1 | 3.045 | DISEASES 7072 | TIA1 | 1.616 | DISEASES |
| Locus | (Waiting for update.) |
| Disease ID | 1867 |
|---|---|
| Disease | thyroid lymphoma |
| Integrated Phenotype | HPO | Name(Total Integrated Phenotypes:14) HP:0000853 | Goiter HP:0002716 | Lymphadenopathy HP:0002098 | Respiratory distress HP:0002094 | Dyspnea HP:0010307 | Stridor HP:0002665 | Lymphoma HP:0002015 | Dysphagia HP:0000872 | Hashimoto thyroiditis HP:0012531 | Pain HP:0002781 | Upper airway obstruction HP:0000475 | Broad neck HP:0001609 | Hoarse voice HP:0000821 | Hypothyroidism HP:0000836 | Hyperthyroidism |
| Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:9) HP:0000872 | Hashimoto's thyroiditis | 9 HP:0100646 | Thyroiditis | 7 HP:0002665 | Lymphoma | 2 HP:0030731 | Carcinoma | 2 HP:0002890 | Thyroid carcinoma | 2 HP:0012191 | B-cell lymphoma | 1 HP:0002895 | Papillary thyroid carcinoma | 1 HP:0012189 | Hodgkin disease | 1 HP:0012190 | T cell lymphoma | 1 |
| Disease ID | 1867 |
|---|---|
| Disease | thyroid lymphoma |
| Manually Symptom | UMLS | Name(Total Manually Symptoms:1) C0020550 | hyperthyroidism |
| Text Mined Symptom | (Waiting for update.) |
Manually Genotype(Total Text Mining Genotypes:0) |
|---|
| (Waiting for update.) |
Text Mining Genotype(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
All Snps(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Annotation(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
Mapped by lexical matching(Total Items:1) | ||||
|---|---|---|---|---|
| HP ID | HP Name | MP ID | MP Name | Annotation |
| HP:0002098 | Respiratory distress | MP:0001954 | respiratory distress | physical difficulty or inability to breathe; shortness of breath |
Mapped by homologous gene(Total Items:14) | ||||
|---|---|---|---|---|
| HP ID | HP Name | MP ID | MP Name | Annotation |
| HP:0000836 | Hyperthyroidism | MP:0020169 | increased thyroid gland weight | higher than average weight of the thyroid gland |
| HP:0012531 | Pain | MP:0011968 | decreased threshold for auditory brainstem response | reduction in the value at which one or more sound frequencies or broadband clicks first elicits a recordable response generated by electrical activity of neurons in the ascending auditory system |
| HP:0002094 | Dyspnea | MP:0014185 | cerebellum atrophy | acquired diminution of the size of the cerebellum associated with wasting as from death and reabsorption of cells, diminished cellular proliferation, decreased cellular volume, pressure, ischemia, malnutrition, reduced function or malfunction, or hormonal |
| HP:0001609 | Hoarse voice | MP:0020220 | decreased tear production | decreased production of the amount of fluid produced in the eye |
| HP:0002098 | Respiratory distress | MP:0014198 | absent pituitary infundibular stalk | absence of the apical portion of the tubular structure extending from the hypothalamus to the posterior lobe of the pituitary gland |
| HP:0000872 | Hashimoto thyroiditis | MP:0012431 | increased lymphoma incidence | greater than the expected number of neoplasms characterized by a proliferation of malignant lymphocytes in lymphoid tissue in a specific population in a given time period |
| HP:0000475 | Broad neck | MP:0012307 | impaired spatial learning | impaired ability to ascertain or acquire spatial location information in order to improve navigation or other behavior using such location cues |
| HP:0002716 | Lymphadenopathy | MP:0020215 | impaired blood coagulation | impaired ability of the blood to clot |
| HP:0002015 | Dysphagia | MP:0020329 | decreased capillary density | reduction in the number of capillaries in a given cross-sectional area of a tissue |
| HP:0000821 | Hypothyroidism | MP:0020169 | increased thyroid gland weight | higher than average weight of the thyroid gland |
| HP:0002665 | Lymphoma | MP:0020154 | impaired humoral immune response | impaired response of the immune system that mediates secreted antibodies produced in B cells |
| HP:0000853 | Goiter | MP:0020169 | increased thyroid gland weight | higher than average weight of the thyroid gland |
| HP:0010307 | Stridor | MP:0013293 | embryonic lethality prior to tooth bud stage | death prior to the appearance of tooth buds (Mus: E12-E12.5) |
| HP:0002781 | Upper airway obstruction | MP:0020039 | increased bone ossification | increase in the formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance |
| Disease ID | 1867 |
|---|---|
| Disease | thyroid lymphoma |
| Case | (Waiting for update.) |