eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| thoracic aortic aneurysm | ||||
| Disease ID | 415 |
|---|---|
| Disease | thoracic aortic aneurysm |
| Definition | An abnormal balloon- or sac-like dilatation in the wall of the THORACIC AORTA. This proximal descending portion of aorta gives rise to the visceral and the parietal branches above the aortic hiatus at the diaphragm. |
| Synonym | aneurysm aortic thoracic aneurysm of thoracic aorta aneurysm of thoracic aorta (disorder) aneurysm thoracic aneurysm, aorta, thoracic aneurysm, thoracic aneurysm, thoracic aortic aneurysms thoracic aortic aneurysm, thoracic aortic aneurysm, thoracic [disease/finding] aortic aneurysms, thoracic aortic thoracic aneurysm thoracic aneurysm thoracic aorta aneurysm thoracic aortic aneurysm (disorder) thoracic aortic aneurysms |
| OMIM | |
| DOID | |
| UMLS | C0162872 |
| MeSH | |
| SNOMED-CT | |
| Comorbidity | UMLS | Disease | Sentences' Count(Total Sentences:34) C0024796 | marfan syndrome | 4 C0003486 | aortic aneurysm | 3 C0003486 | aortic aneurysms | 2 C0162871 | abdominal aortic aneurysm | 2 C0162871 | abdominal aortic aneurysms | 2 C0007766 | intracranial aneurysm | 2 C0040053 | thrombus | 2 C0007766 | cranial aneurysm | 2 C0039128 | syphilis | 2 C0020538 | hypertension | 1 C0035078 | renal failure | 1 C0032285 | pneumoniae | 1 C0004153 | atherosclerosis | 1 C0153188 | tertiary syphilis | 1 C0024141 | systemic lupus erythematosus | 1 C2697932 | loeys-dietz syndrome | 1 C0007177 | cardiac tamponade | 1 C0004943 | behcet's disease | 1 C0003504 | aortic regurgitation | 1 C0039263 | takayasu arteritis | 1 C0030567 | parkinson's disease | 1 C0010495 | cutis laxa | 1 C0042769 | virus infection | 1 C0018799 | heart disease | 1 C0010068 | coronary artery disease | 1 C0007766 | intracranial aneurysms | 1 C0409974 | lupus erythematosus | 1 C0040053 | thrombosis | 1 C0031511 | pheochromocytoma | 1 C0026266 | mitral regurgitation | 1 C0040583 | tracheal stenosis | 1 C0152021 | congenital heart disease | 1 C0009782 | connective tissue disease | 1 C0043194 | wiskott-aldrich syndrome | 1 |
| Curated Gene | Entrez_id | Symbol | Resource(Total Genes:11) |
| Inferring Gene | Entrez_id | Symbol | Resource(Total Genes:6) |
| Text Mined Gene | Entrez_id | Symbol | Score | Resource(Total Genes:48) 11093 | ADAMTS13 | 1.061 | DISEASES 92949 | ADAMTSL1 | 3.291 | DISEASES 64400 | AKTIP | 1.237 | DISEASES 468 | ATF4 | 1.641 | DISEASES 149466 | C1orf210 | 3.012 | DISEASES 1003 | CDH5 | 1.559 | DISEASES 100272147 | CMC4 | 3.416 | DISEASES 1306 | COL15A1 | 2.594 | DISEASES 1289 | COL5A1 | 1.707 | DISEASES 1290 | COL5A2 | 1.958 | DISEASES 1485 | CTAG1B | 1.757 | DISEASES 1490 | CTGF | 1.09 | DISEASES 79659 | DYNC2H1 | 2.564 | DISEASES 2200 | FBN1 | 5.682 | DISEASES 2316 | FLNA | 1.315 | DISEASES 342184 | FMN1 | 1.623 | DISEASES 2835 | GPR12 | 3.235 | DISEASES 100506195 | LARGE-AS1 | 2.717 | DISEASES 4052 | LTBP1 | 2.093 | DISEASES 219541 | MED19 | 2.061 | DISEASES 8076 | MFAP5 | 3.49 | DISEASES 4312 | MMP1 | 2.151 | DISEASES 4326 | MMP17 | 2.274 | DISEASES 4318 | MMP9 | 3.295 | DISEASES 4629 | MYH11 | 4.136 | DISEASES 4638 | MYLK | 3.664 | DISEASES 93649 | MYOCD | 1.488 | DISEASES 50863 | NTM | 2.691 | DISEASES 84033 | OBSCN | 2.482 | DISEASES 5287 | PIK3C2B | 2.314 | DISEASES 5592 | PRKG1 | 2.222 | DISEASES 10411 | RAPGEF3 | 1.346 | DISEASES 11069 | RAPGEF4 | 1.395 | DISEASES 57674 | RNF213 | 1.908 | DISEASES 6283 | S100A12 | 2.702 | DISEASES 51150 | SDF4 | 1.162 | DISEASES 5270 | SERPINE2 | 1.361 | DISEASES 81031 | SLC2A10 | 3.962 | DISEASES 4088 | SMAD3 | 3.63 | DISEASES 4089 | SMAD4 | 1.255 | DISEASES 6525 | SMTN | 1.947 | DISEASES 6696 | SPP1 | 1.309 | DISEASES 7021 | TFAP2B | 1.828 | DISEASES 7042 | TGFB2 | 3.824 | DISEASES 7046 | TGFBR1 | 4.306 | DISEASES 7048 | TGFBR2 | 4.577 | DISEASES 7058 | THBS2 | 1.295 | DISEASES 7148 | TNXB | 1.812 | DISEASES |
| Locus | (Waiting for update.) |
| Disease ID | 415 |
|---|---|
| Disease | thoracic aortic aneurysm |
| Manually Symptom | UMLS | Name(Total Manually Symptoms:12) C1550639 | fistula C1393529 | vascular complications C1322286 | thymic carcinoma C0684249 | lung cancer C0542142 | recurrent laryngeal nerve paralysis C0302148 | thrombus C0281839 | esophageal rupture C0264971 | gastroepiploic artery aneurysm C0262576 | nerve paralysis C0085652 | pyoderma gangrenosum C0014860 | esophageal perforation C0004153 | atherosclerosis |
| Text Mined Symptom | UMLS | Name | Sentences' Count(Total Symptoms:2) |
Manually Genotype(Total Text Mining Genotypes:0) |
|---|
| (Waiting for update.) |
Text Mining Genotype(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
All Snps(Total Genotypes:42) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| snpId | pubmedId | geneId | geneSymbol | diseaseId | sourceId | sentence | score | Year | geneSymbol_dbSNP | CHROMOSOME | POS | REF | ALT |
| rs1036476 | 21909107 | 2200 | FBN1 | umls:C0162872 | GAD | [Genome-wide association study identifies a susceptibility locus for thoracic aortic aneurysms and aortic dissections spanning FBN1 at 15q21.1.] | 0.127177041 | 2011 | FBN1 | 15 | 48622578 | T | C |
| rs1042713 | 25171434 | 154 | ADRB2 | umls:C0162872 | BeFree | We genotyped β2-adrenergic receptor (ADRB2) (Arg16Gly and Gln27Glu), cytochrome P450 3A4 (rs2246709, rs4646437), and uridine diphosphate glucuronosyltransferase 1A1 (UGT1A1) (rs4148323 [allele A, *6], rs12479045, rs4148328, rs4663971, rs12052787, rs4148329, A (TA)6/7 TAA [seven-repeat allele, *28]). | 0.000271442 | 2015 | ADRB2 | 5 | 148826877 | G | A |
| rs1042713 | 25171434 | 1576 | CYP3A4 | umls:C0162872 | BeFree | We genotyped β2-adrenergic receptor (ADRB2) (Arg16Gly and Gln27Glu), cytochrome P450 3A4 (rs2246709, rs4646437), and uridine diphosphate glucuronosyltransferase 1A1 (UGT1A1) (rs4148323 [allele A, *6], rs12479045, rs4148328, rs4663971, rs12052787, rs4148329, A (TA)6/7 TAA [seven-repeat allele, *28]). | 0.000271442 | 2015 | ADRB2 | 5 | 148826877 | G | A |
| rs1042714 | 25171434 | 154 | ADRB2 | umls:C0162872 | BeFree | We genotyped β2-adrenergic receptor (ADRB2) (Arg16Gly and Gln27Glu), cytochrome P450 3A4 (rs2246709, rs4646437), and uridine diphosphate glucuronosyltransferase 1A1 (UGT1A1) (rs4148323 [allele A, *6], rs12479045, rs4148328, rs4663971, rs12052787, rs4148329, A (TA)6/7 TAA [seven-repeat allele, *28]). | 0.000271442 | 2015 | ADRB2 | 5 | 148826910 | G | C,T |
| rs1042714 | 25171434 | 1576 | CYP3A4 | umls:C0162872 | BeFree | We genotyped β2-adrenergic receptor (ADRB2) (Arg16Gly and Gln27Glu), cytochrome P450 3A4 (rs2246709, rs4646437), and uridine diphosphate glucuronosyltransferase 1A1 (UGT1A1) (rs4148323 [allele A, *6], rs12479045, rs4148328, rs4663971, rs12052787, rs4148329, A (TA)6/7 TAA [seven-repeat allele, *28]). | 0.000271442 | 2015 | ADRB2 | 5 | 148826910 | G | C,T |
| rs12052787 | 25171434 | 1576 | CYP3A4 | umls:C0162872 | BeFree | We genotyped β2-adrenergic receptor (ADRB2) (Arg16Gly and Gln27Glu), cytochrome P450 3A4 (rs2246709, rs4646437), and uridine diphosphate glucuronosyltransferase 1A1 (UGT1A1) (rs4148323 [allele A, *6], rs12479045, rs4148328, rs4663971, rs12052787, rs4148329, A (TA)6/7 TAA [seven-repeat allele, *28]). | 0.000271442 | 2015 | UGT1A10;UGT1A8;UGT1A7;UGT1A6;UGT1A5;UGT1A9;UGT1A4;UGT1A3 | 2 | 233757935 | C | T |
| rs12052787 | 25171434 | 154 | ADRB2 | umls:C0162872 | BeFree | We genotyped β2-adrenergic receptor (ADRB2) (Arg16Gly and Gln27Glu), cytochrome P450 3A4 (rs2246709, rs4646437), and uridine diphosphate glucuronosyltransferase 1A1 (UGT1A1) (rs4148323 [allele A, *6], rs12479045, rs4148328, rs4663971, rs12052787, rs4148329, A (TA)6/7 TAA [seven-repeat allele, *28]). | 0.000271442 | 2015 | UGT1A10;UGT1A8;UGT1A7;UGT1A6;UGT1A5;UGT1A9;UGT1A4;UGT1A3 | 2 | 233757935 | C | T |
| rs12479045 | 25171434 | 154 | ADRB2 | umls:C0162872 | BeFree | We genotyped β2-adrenergic receptor (ADRB2) (Arg16Gly and Gln27Glu), cytochrome P450 3A4 (rs2246709, rs4646437), and uridine diphosphate glucuronosyltransferase 1A1 (UGT1A1) (rs4148323 [allele A, *6], rs12479045, rs4148328, rs4663971, rs12052787, rs4148329, A (TA)6/7 TAA [seven-repeat allele, *28]). | 0.000271442 | 2015 | UGT1A10;UGT1A8;UGT1A7;UGT1A6;UGT1A5;UGT1A9;UGT1A4;UGT1A1;UGT1A3 | 2 | 233764942 | G | A,C |
| rs12479045 | 25171434 | 1576 | CYP3A4 | umls:C0162872 | BeFree | We genotyped β2-adrenergic receptor (ADRB2) (Arg16Gly and Gln27Glu), cytochrome P450 3A4 (rs2246709, rs4646437), and uridine diphosphate glucuronosyltransferase 1A1 (UGT1A1) (rs4148323 [allele A, *6], rs12479045, rs4148328, rs4663971, rs12052787, rs4148329, A (TA)6/7 TAA [seven-repeat allele, *28]). | 0.000271442 | 2015 | UGT1A10;UGT1A8;UGT1A7;UGT1A6;UGT1A5;UGT1A9;UGT1A4;UGT1A1;UGT1A3 | 2 | 233764942 | G | A,C |
| rs17718511 | 21087323 | 11005 | SPINK5 | umls:C0162872 | BeFree | We also found that four SNPs [rs17718511 (P = 0.033), rs17860502 (P = 0.031), rs60978485 (P = 0.005), rs17718737 (P = 0.023)] and the haplotype TAA (P = 0.02) in the SPINK5 gene showed associations with the susceptibility of the allergic type of AD (ADe). | 0.000271442 | 2010 | SPINK5 | 5 | 148072009 | A | G |
| rs17718737 | 21087323 | 11005 | SPINK5 | umls:C0162872 | BeFree | We also found that four SNPs [rs17718511 (P = 0.033), rs17860502 (P = 0.031), rs60978485 (P = 0.005), rs17718737 (P = 0.023)] and the haplotype TAA (P = 0.02) in the SPINK5 gene showed associations with the susceptibility of the allergic type of AD (ADe). | 0.000271442 | 2010 | SPINK5 | 5 | 148112898 | T | C |
| rs17860502 | 21087323 | 11005 | SPINK5 | umls:C0162872 | BeFree | We also found that four SNPs [rs17718511 (P = 0.033), rs17860502 (P = 0.031), rs60978485 (P = 0.005), rs17718737 (P = 0.023)] and the haplotype TAA (P = 0.02) in the SPINK5 gene showed associations with the susceptibility of the allergic type of AD (ADe). | 0.000271442 | 2010 | SPINK5 | 5 | 148086438 | G | A |
| rs1799752 | 25120286 | 4313 | MMP2 | umls:C0162872 | BeFree | Interestingly, the rs4986790 TLR4 polymorphism confers a higher susceptibility for sporadic TAA (OR = 14.4, P = 0.0008) and it represents, together with rs1799752 ACE, rs3918242 MMP-9, and rs2285053 MMP-2 SNPs, an independent sporadic TAA risk factor. | 0.200814326 | 2014 | ACE | 17 | 63488529 | - | ATACAGTCACTTTTTTTTTTTTTTTGAGACGGAGTCTCGCTCTGTCGCCC,G |
| rs1799752 | 25120286 | 4318 | MMP9 | umls:C0162872 | BeFree | Interestingly, the rs4986790 TLR4 polymorphism confers a higher susceptibility for sporadic TAA (OR = 14.4, P = 0.0008) and it represents, together with rs1799752 ACE, rs3918242 MMP-9, and rs2285053 MMP-2 SNPs, an independent sporadic TAA risk factor. | 0.200814326 | 2014 | ACE | 17 | 63488529 | - | ATACAGTCACTTTTTTTTTTTTTTTGAGACGGAGTCTCGCTCTGTCGCCC,G |
| rs1799752 | 25120286 | 1636 | ACE | umls:C0162872 | BeFree | Interestingly, the rs4986790 TLR4 polymorphism confers a higher susceptibility for sporadic TAA (OR = 14.4, P = 0.0008) and it represents, together with rs1799752 ACE, rs3918242 MMP-9, and rs2285053 MMP-2 SNPs, an independent sporadic TAA risk factor. | 0.000814326 | 2014 | ACE | 17 | 63488529 | - | ATACAGTCACTTTTTTTTTTTTTTTGAGACGGAGTCTCGCTCTGTCGCCC,G |
| rs1799971 | 19018716 | 4988 | OPRM1 | umls:C0162872 | BeFree | Here, we evaluate whether any of the five tag SNPs (A118G, IVS2+G691C, IVS3+G5953A, IVS3+A8449G and TAA+A2109G) representing the four linkage disequilibrium blocks of the OPRM1 gene influences postoperative analgesic requirements. | 0.000542884 | 2008 | OPRM1 | 6 | 154039662 | A | G |
| rs2246709 | 25171434 | 154 | ADRB2 | umls:C0162872 | BeFree | We genotyped β2-adrenergic receptor (ADRB2) (Arg16Gly and Gln27Glu), cytochrome P450 3A4 (rs2246709, rs4646437), and uridine diphosphate glucuronosyltransferase 1A1 (UGT1A1) (rs4148323 [allele A, *6], rs12479045, rs4148328, rs4663971, rs12052787, rs4148329, A (TA)6/7 TAA [seven-repeat allele, *28]). | 0.000271442 | 2015 | CYP3A4 | 7 | 99768096 | A | G |
| rs2246709 | 25171434 | 1576 | CYP3A4 | umls:C0162872 | BeFree | We genotyped β2-adrenergic receptor (ADRB2) (Arg16Gly and Gln27Glu), cytochrome P450 3A4 (rs2246709, rs4646437), and uridine diphosphate glucuronosyltransferase 1A1 (UGT1A1) (rs4148323 [allele A, *6], rs12479045, rs4148328, rs4663971, rs12052787, rs4148329, A (TA)6/7 TAA [seven-repeat allele, *28]). | 0.000271442 | 2015 | CYP3A4 | 7 | 99768096 | A | G |
| rs2285053 | 25120286 | 1636 | ACE | umls:C0162872 | BeFree | Interestingly, the rs4986790 TLR4 polymorphism confers a higher susceptibility for sporadic TAA (OR = 14.4, P = 0.0008) and it represents, together with rs1799752 ACE, rs3918242 MMP-9, and rs2285053 MMP-2 SNPs, an independent sporadic TAA risk factor. | 0.000814326 | 2014 | MMP2 | 16 | 55478465 | C | T |
| rs2285053 | 25120286 | 4318 | MMP9 | umls:C0162872 | BeFree | Interestingly, the rs4986790 TLR4 polymorphism confers a higher susceptibility for sporadic TAA (OR = 14.4, P = 0.0008) and it represents, together with rs1799752 ACE, rs3918242 MMP-9, and rs2285053 MMP-2 SNPs, an independent sporadic TAA risk factor. | 0.200814326 | 2014 | MMP2 | 16 | 55478465 | C | T |
| rs2285053 | 25120286 | 4313 | MMP2 | umls:C0162872 | BeFree | Interestingly, the rs4986790 TLR4 polymorphism confers a higher susceptibility for sporadic TAA (OR = 14.4, P = 0.0008) and it represents, together with rs1799752 ACE, rs3918242 MMP-9, and rs2285053 MMP-2 SNPs, an independent sporadic TAA risk factor. | 0.200814326 | 2014 | MMP2 | 16 | 55478465 | C | T |
| rs3918242 | 25120286 | 4318 | MMP9 | umls:C0162872 | BeFree | Interestingly, the rs4986790 TLR4 polymorphism confers a higher susceptibility for sporadic TAA (OR = 14.4, P = 0.0008) and it represents, together with rs1799752 ACE, rs3918242 MMP-9, and rs2285053 MMP-2 SNPs, an independent sporadic TAA risk factor. | 0.200814326 | 2014 | MMP9 | 20 | 46007337 | C | T |
| rs3918242 | 25120286 | 1636 | ACE | umls:C0162872 | BeFree | Interestingly, the rs4986790 TLR4 polymorphism confers a higher susceptibility for sporadic TAA (OR = 14.4, P = 0.0008) and it represents, together with rs1799752 ACE, rs3918242 MMP-9, and rs2285053 MMP-2 SNPs, an independent sporadic TAA risk factor. | 0.000814326 | 2014 | MMP9 | 20 | 46007337 | C | T |
| rs3918242 | 25120286 | 4313 | MMP2 | umls:C0162872 | BeFree | Interestingly, the rs4986790 TLR4 polymorphism confers a higher susceptibility for sporadic TAA (OR = 14.4, P = 0.0008) and it represents, together with rs1799752 ACE, rs3918242 MMP-9, and rs2285053 MMP-2 SNPs, an independent sporadic TAA risk factor. | 0.200814326 | 2014 | MMP9 | 20 | 46007337 | C | T |
| rs4148323 | 11906189 | 54658 | UGT1A1 | umls:C0162872 | BeFree | Our results indicate that homozygosity and compound heterozygosity for mutations in the UGT1A1 gene promoter (T-3263G and A[TA](7)TAA) and/or exon 1 of the gene (G211A) could explain the hyperbilirubinemia seen in the majority of individuals with Gilbert's syndrome. | 0.004071628 | 2002 | UGT1A10;UGT1A8;UGT1A7;UGT1A6;UGT1A5;UGT1A9;UGT1A4;UGT1A1;UGT1A3 | 2 | 233760498 | G | A |
| rs4148323 | 25171434 | 1576 | CYP3A4 | umls:C0162872 | BeFree | We genotyped β2-adrenergic receptor (ADRB2) (Arg16Gly and Gln27Glu), cytochrome P450 3A4 (rs2246709, rs4646437), and uridine diphosphate glucuronosyltransferase 1A1 (UGT1A1) (rs4148323 [allele A, *6], rs12479045, rs4148328, rs4663971, rs12052787, rs4148329, A (TA)6/7 TAA [seven-repeat allele, *28]). | 0.000271442 | 2015 | UGT1A10;UGT1A8;UGT1A7;UGT1A6;UGT1A5;UGT1A9;UGT1A4;UGT1A1;UGT1A3 | 2 | 233760498 | G | A |
| rs4148323 | 25171434 | 154 | ADRB2 | umls:C0162872 | BeFree | We genotyped β2-adrenergic receptor (ADRB2) (Arg16Gly and Gln27Glu), cytochrome P450 3A4 (rs2246709, rs4646437), and uridine diphosphate glucuronosyltransferase 1A1 (UGT1A1) (rs4148323 [allele A, *6], rs12479045, rs4148328, rs4663971, rs12052787, rs4148329, A (TA)6/7 TAA [seven-repeat allele, *28]). | 0.000271442 | 2015 | UGT1A10;UGT1A8;UGT1A7;UGT1A6;UGT1A5;UGT1A9;UGT1A4;UGT1A1;UGT1A3 | 2 | 233760498 | G | A |
| rs4148328 | 25171434 | 1576 | CYP3A4 | umls:C0162872 | BeFree | We genotyped β2-adrenergic receptor (ADRB2) (Arg16Gly and Gln27Glu), cytochrome P450 3A4 (rs2246709, rs4646437), and uridine diphosphate glucuronosyltransferase 1A1 (UGT1A1) (rs4148323 [allele A, *6], rs12479045, rs4148328, rs4663971, rs12052787, rs4148329, A (TA)6/7 TAA [seven-repeat allele, *28]). | 0.000271442 | 2015 | UGT1A10;UGT1A8;UGT1A7;UGT1A6;UGT1A5;UGT1A9;UGT1A4;UGT1A1;UGT1A3 | 2 | 233769013 | C | T |
| rs4148328 | 25171434 | 154 | ADRB2 | umls:C0162872 | BeFree | We genotyped β2-adrenergic receptor (ADRB2) (Arg16Gly and Gln27Glu), cytochrome P450 3A4 (rs2246709, rs4646437), and uridine diphosphate glucuronosyltransferase 1A1 (UGT1A1) (rs4148323 [allele A, *6], rs12479045, rs4148328, rs4663971, rs12052787, rs4148329, A (TA)6/7 TAA [seven-repeat allele, *28]). | 0.000271442 | 2015 | UGT1A10;UGT1A8;UGT1A7;UGT1A6;UGT1A5;UGT1A9;UGT1A4;UGT1A1;UGT1A3 | 2 | 233769013 | C | T |
| rs4148329 | 25171434 | 1576 | CYP3A4 | umls:C0162872 | BeFree | We genotyped β2-adrenergic receptor (ADRB2) (Arg16Gly and Gln27Glu), cytochrome P450 3A4 (rs2246709, rs4646437), and uridine diphosphate glucuronosyltransferase 1A1 (UGT1A1) (rs4148323 [allele A, *6], rs12479045, rs4148328, rs4663971, rs12052787, rs4148329, A (TA)6/7 TAA [seven-repeat allele, *28]). | 0.000271442 | 2015 | UGT1A10;UGT1A8;UGT1A7;UGT1A6;UGT1A5;UGT1A9;UGT1A4;UGT1A1;UGT1A3 | 2 | 233773416 | C | T |
| rs4148329 | 25171434 | 154 | ADRB2 | umls:C0162872 | BeFree | We genotyped β2-adrenergic receptor (ADRB2) (Arg16Gly and Gln27Glu), cytochrome P450 3A4 (rs2246709, rs4646437), and uridine diphosphate glucuronosyltransferase 1A1 (UGT1A1) (rs4148323 [allele A, *6], rs12479045, rs4148328, rs4663971, rs12052787, rs4148329, A (TA)6/7 TAA [seven-repeat allele, *28]). | 0.000271442 | 2015 | UGT1A10;UGT1A8;UGT1A7;UGT1A6;UGT1A5;UGT1A9;UGT1A4;UGT1A1;UGT1A3 | 2 | 233773416 | C | T |
| rs4646437 | 25171434 | 1576 | CYP3A4 | umls:C0162872 | BeFree | We genotyped β2-adrenergic receptor (ADRB2) (Arg16Gly and Gln27Glu), cytochrome P450 3A4 (rs2246709, rs4646437), and uridine diphosphate glucuronosyltransferase 1A1 (UGT1A1) (rs4148323 [allele A, *6], rs12479045, rs4148328, rs4663971, rs12052787, rs4148329, A (TA)6/7 TAA [seven-repeat allele, *28]). | 0.000271442 | 2015 | CYP3A4 | 7 | 99767460 | G | A |
| rs4646437 | 25171434 | 154 | ADRB2 | umls:C0162872 | BeFree | We genotyped β2-adrenergic receptor (ADRB2) (Arg16Gly and Gln27Glu), cytochrome P450 3A4 (rs2246709, rs4646437), and uridine diphosphate glucuronosyltransferase 1A1 (UGT1A1) (rs4148323 [allele A, *6], rs12479045, rs4148328, rs4663971, rs12052787, rs4148329, A (TA)6/7 TAA [seven-repeat allele, *28]). | 0.000271442 | 2015 | CYP3A4 | 7 | 99767460 | G | A |
| rs4663971 | 25171434 | 1576 | CYP3A4 | umls:C0162872 | BeFree | We genotyped β2-adrenergic receptor (ADRB2) (Arg16Gly and Gln27Glu), cytochrome P450 3A4 (rs2246709, rs4646437), and uridine diphosphate glucuronosyltransferase 1A1 (UGT1A1) (rs4148323 [allele A, *6], rs12479045, rs4148328, rs4663971, rs12052787, rs4148329, A (TA)6/7 TAA [seven-repeat allele, *28]). | 0.000271442 | 2015 | UGT1A10;UGT1A8;UGT1A7;UGT1A6;UGT1A5;UGT1A9;UGT1A4;UGT1A1;UGT1A3 | 2 | 233765606 | C | G |
| rs4663971 | 25171434 | 154 | ADRB2 | umls:C0162872 | BeFree | We genotyped β2-adrenergic receptor (ADRB2) (Arg16Gly and Gln27Glu), cytochrome P450 3A4 (rs2246709, rs4646437), and uridine diphosphate glucuronosyltransferase 1A1 (UGT1A1) (rs4148323 [allele A, *6], rs12479045, rs4148328, rs4663971, rs12052787, rs4148329, A (TA)6/7 TAA [seven-repeat allele, *28]). | 0.000271442 | 2015 | UGT1A10;UGT1A8;UGT1A7;UGT1A6;UGT1A5;UGT1A9;UGT1A4;UGT1A1;UGT1A3 | 2 | 233765606 | C | G |
| rs4986790 | 25120286 | 4318 | MMP9 | umls:C0162872 | BeFree | Interestingly, the rs4986790 TLR4 polymorphism confers a higher susceptibility for sporadic TAA (OR = 14.4, P = 0.0008) and it represents, together with rs1799752 ACE, rs3918242 MMP-9, and rs2285053 MMP-2 SNPs, an independent sporadic TAA risk factor. | 0.200814326 | 2014 | TLR4 | 9 | 117713024 | A | G |
| rs4986790 | 25120286 | 4313 | MMP2 | umls:C0162872 | BeFree | Interestingly, the rs4986790 TLR4 polymorphism confers a higher susceptibility for sporadic TAA (OR = 14.4, P = 0.0008) and it represents, together with rs1799752 ACE, rs3918242 MMP-9, and rs2285053 MMP-2 SNPs, an independent sporadic TAA risk factor. | 0.200814326 | 2014 | TLR4 | 9 | 117713024 | A | G |
| rs4986790 | 25120286 | 1636 | ACE | umls:C0162872 | BeFree | Interestingly, the rs4986790 TLR4 polymorphism confers a higher susceptibility for sporadic TAA (OR = 14.4, P = 0.0008) and it represents, together with rs1799752 ACE, rs3918242 MMP-9, and rs2285053 MMP-2 SNPs, an independent sporadic TAA risk factor. | 0.000814326 | 2014 | TLR4 | 9 | 117713024 | A | G |
| rs58597806 | 15286088 | 54658 | UGT1A1 | umls:C0162872 | BeFree | The aim of this study was to evaluate the functional consequence of the UGT1A1(TA)(7)TAA (UGT1A1(*)28), UGT1A9 766G>A (D256N; UGT1A9(*)5), and UGT1A9 98T>C (M33T; UGT1A9(*)3) variants in Caucasian patients treated with irinotecan. | 0.004071628 | 2004 | UGT1A10;UGT1A8;UGT1A9 | 2 | 233672700 | G | A |
| rs60978485 | 21087323 | 11005 | SPINK5 | umls:C0162872 | BeFree | We also found that four SNPs [rs17718511 (P = 0.033), rs17860502 (P = 0.031), rs60978485 (P = 0.005), rs17718737 (P = 0.023)] and the haplotype TAA (P = 0.02) in the SPINK5 gene showed associations with the susceptibility of the allergic type of AD (ADe). | 0.000271442 | 2010 | SPINK5 | 5 | 148091116 | A | T |
| rs72551330 | 15286088 | 54658 | UGT1A1 | umls:C0162872 | BeFree | The aim of this study was to evaluate the functional consequence of the UGT1A1(TA)(7)TAA (UGT1A1(*)28), UGT1A9 766G>A (D256N; UGT1A9(*)5), and UGT1A9 98T>C (M33T; UGT1A9(*)3) variants in Caucasian patients treated with irinotecan. | 0.004071628 | 2004 | UGT1A10;UGT1A8;UGT1A9 | 2 | 233672032 | T | C |
| rs900 | 24707114 | 7042 | TGFB2 | umls:C0162872 | BeFree | Role of TGF-β pathway polymorphisms in sporadic thoracic aortic aneurysm: rs900 TGF-β2 is a marker of differential gender susceptibility. | 0.121357209 | 2014 | TGFB2;TGFB2-OT1 | 1 | 218441563 | A | T |
GWASdb Annotation(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:107) | |||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CHR | POS | SNPID | REF | ALT | ORI_SNPID | PMID | P_VALUE | P_VALUE_TEXT | OR/BETA | CI95_TEXT | GWAS_INITIAL_SAMPLE_SIZE | SUB_POPULATION | SUPER_POPULATION | GWAS_TRAIT | HPO_ID | HPO_TERM | DO_ID | DO_TERM | MESH_ID | MESH_TERM | EFO_ID | EFO_TERM | DOLITE_TERM | RISK_ALLELE | PUBLICATION_TYPE | AA | GENE_SYMBOL | TYPE | REFGENE |
| 15 | 48692460 | rs7171330 | T | A | rs7171330 | 21909107 | 3.40E-04 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48698503 | rs2013984 | T | C | rs2013984 | 21909107 | 3.50E-04 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48699486 | rs16960886 | G | A | rs16960886 | 21909107 | 3.70E-07 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48699929 | rs2114438 | T | C | rs2114438 | 21909107 | 1.60E-04 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48702873 | rs1042078 | G | A | rs1042078 | 21909107 | 5.10E-08 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48705206 | rs16960901 | T | C | rs16960901 | 21909107 | 1.70E-10 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48706571 | rs12916536 | A | G | rs12916536 | 21909107 | 2.40E-04 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48714838 | rs1467953 | T | G | rs1467953 | 21909107 | 2.30E-04 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48715448 | rs9920570 | A | G | rs9920570 | 21909107 | 2.30E-04 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48716853 | rs2015637 | T | C | rs2015637 | 21909107 | 2.70E-07 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48720271 | rs3929051 | C | T | rs3929051 | 21909107 | 1.70E-04 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48724768 | rs8034591 | C | T | rs8034591 | 21909107 | 1.90E-08 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48728634 | rs2042747 | C | T | rs2042747 | 21909107 | 6.90E-11 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48736684 | rs2303502 | A | T | rs2303502 | 21909107 | 5.00E-11 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48739274 | rs2303500 | A | G | rs2303500 | 21909107 | 4.70E-11 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48740097 | rs8029993 | C | T | rs8029993 | 21909107 | 8.20E-05 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48744005 | rs4775762 | T | C | rs4775762 | 21909107 | 5.00E-11 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48747440 | rs2555470 | C | T | rs2555470 | 21909107 | 7.50E-05 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48750520 | rs1812873 | C | A | rs1812873 | 21909107 | 7.20E-05 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48751329 | rs714290 | C | G | rs714290 | 21909107 | 6.70E-11 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48753145 | rs2466792 | C | A | rs2466792 | 21909107 | 7.00E-05 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48753624 | rs2433394 | C | A | rs2433394 | 21909107 | 6.90E-05 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48757195 | rs10519177 | A | G | rs10519177 | 21909107 | 6.40E-05 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48759291 | rs4774517 | G | T | rs4774517 | 21909107 | 3.80E-11 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48763754 | rs7174973 | A | G | rs7174973 | 21909107 | 1.30E-04 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48766015 | rs9806323 | T | A | rs9806323 | 21909107 | 1.20E-10 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48770580 | rs2413906 | A | G | rs2413906 | 21909107 | 7.30E-05 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48774288 | rs11634866 | A | G | rs11634866 | 21909107 | 4.30E-11 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48782563 | rs11635140 | T | C | rs11635140 | 21909107 | 2.20E-08 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48784497 | rs11070644 | T | C | rs11070644 | 21909107 | 7.50E-05 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48786917 | rs11635605 | C | T | rs11635605 | 21909107 | 1.70E-04 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48787245 | rs6493325 | T | C | rs6493325 | 21909107 | 1.70E-04 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48789634 | rs140605 | T | C | rs140605 | 21909107 | 4.30E-11 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48803839 | rs9806163 | T | C | rs9806163 | 21909107 | 4.70E-11 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48805637 | rs2306352 | G | A | rs2306352 | 21909107 | 4.40E-11 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48806027 | rs8034829 | T | C | rs8034829 | 21909107 | 1.50E-07 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48806539 | rs16961065 | C | T | rs16961065 | 21909107 | 1.40E-07 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48809428 | rs6493327 | G | A | rs6493327 | 21909107 | 1.50E-07 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48810499 | rs7184016 | G | T | rs7184016 | 21909107 | 4.70E-11 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48812020 | rs755251 | A | G | rs755251 | 21909107 | 7.50E-05 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48814297 | rs11634611 | G | A | rs11634611 | 21909107 | 1.50E-04 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48819502 | rs6493328 | G | A | rs6493328 | 21909107 | 1.70E-08 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48823770 | rs8026752 | A | G | rs8026752 | 21909107 | 1.00E-07 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48834860 | rs598029 | A | G | rs598029 | 21909107 | 3.30E-05 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48835355 | rs8041668 | T | C | rs8041668 | 21909107 | 5.40E-11 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48835935 | rs589668 | C | T | rs589668 | 21909107 | 6.00E-11 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48840835 | rs595244 | C | T | rs595244 | 21909107 | 1.40E-04 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48843598 | rs626492 | C | T | rs626492 | 21909107 | 3.30E-05 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48847733 | rs683282 | T | C | rs683282 | 21909107 | 2.90E-05 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48849728 | rs2437948 | C | T | rs2437948 | 21909107 | 4.30E-05 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48859733 | rs2448485 | A | G | rs2448485 | 21909107 | 5.60E-11 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48859966 | rs10744953 | T | C | rs10744953 | 21909107 | 1.60E-04 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48864367 | rs682938 | A | G | rs682938 | 21909107 | 6.80E-11 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48876157 | rs1678978 | C | T | rs1678978 | 21909107 | 2.30E-05 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48879291 | rs627634 | C | T | rs627634 | 21909107 | 1.20E-04 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48883696 | rs1354738 | T | C | rs1354738 | 21909107 | 4.00E-11 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48885005 | rs686861 | A | G | rs686861 | 21909107 | 1.10E-04 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48885877 | rs2456475 | G | A | rs2456475 | 21909107 | 1.10E-04 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48888988 | rs1506524 | A | T | rs1506524 | 21909107 | 5.00E-05 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48891107 | rs655015 | T | C | rs655015 | 21909107 | 1.10E-04 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48891771 | rs682737 | G | A | rs682737 | 21909107 | 1.10E-04 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48891965 | rs668842 | C | T | rs668842 | 21909107 | 2.30E-05 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48892939 | rs920184 | C | T | rs920184 | 21909107 | 2.10E-11 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48893649 | rs2455925 | T | C | rs2455925 | 21909107 | 1.10E-04 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48894200 | rs591519 | A | T | rs591519 | 21909107 | 1.10E-04 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48896830 | rs1678979 | T | C | rs1678979 | 21909107 | 2.80E-05 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48897282 | rs636178 | C | T | rs636178 | 21909107 | 1.10E-04 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48899399 | rs2466790 | G | A | rs2466790 | 21909107 | 1.10E-04 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48900097 | rs1678981 | C | T | rs1678981 | 21909107 | 1.00E-04 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48901420 | rs1678982 | C | G | rs1678982 | 21909107 | 1.00E-04 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48906577 | rs612617 | A | G | rs612617 | 21909107 | 2.60E-05 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48910240 | rs1807301 | A | G | rs1807301 | 21909107 | 5.20E-05 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48914775 | rs1036476 | T | C | rs1036476 | 21909107 | 6.00E-13 | NA | 1.9 | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48914926 | rs1036477 | A | G | rs1036477 | 21909107 | 1.40E-07 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48915884 | rs2118181 | T | C | rs2118181 | 21909107 | 1.30E-07 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48922360 | rs689304 | C | T | rs689304 | 21909107 | 1.30E-04 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48926002 | rs2437946 | G | A | rs2437946 | 21909107 | 1.20E-10 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48926202 | rs625034 | T | C | rs625034 | 21909107 | 2.30E-04 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48930645 | rs1678983 | T | C | rs1678983 | 21909107 | 3.00E-07 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48931451 | rs2247876 | T | C | rs2247876 | 21909107 | 1.40E-10 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48939046 | rs6493333 | T | C | rs6493333 | 21909107 | 1.10E-11 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48944272 | rs2289136 | G | A | rs2289136 | 21909107 | 2.20E-11 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48944563 | rs4775770 | A | G | rs4775770 | 21909107 | 7.00E-12 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48947962 | rs1848053 | G | A | rs1848053 | 21909107 | 2.00E-04 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48948291 | rs8042197 | C | T | rs8042197 | 21909107 | 1.60E-04 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48949078 | rs7166445 | G | A | rs7166445 | 21909107 | 6.70E-04 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48949710 | rs1857910 | C | T | rs1857910 | 21909107 | 2.60E-04 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48950277 | rs893160 | G | C | rs893160 | 21909107 | 1.70E-04 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48951277 | rs2099562 | A | G | rs2099562 | 21909107 | 2.50E-09 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48951550 | rs7173026 | C | T | rs7173026 | 21909107 | 2.10E-09 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48951774 | rs7173410 | C | T | rs7173410 | 21909107 | 2.10E-09 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48954766 | rs931782 | A | T | rs931782 | 21909107 | 3.10E-09 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48956267 | rs8038489 | T | C | rs8038489 | 21909107 | 3.40E-09 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48957743 | rs2043682 | C | A | rs2043682 | 21909107 | 3.00E-09 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48960590 | rs4775771 | G | T | rs4775771 | 21909107 | 4.00E-09 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48964367 | rs12442299 | G | A | rs12442299 | 21909107 | 8.90E-09 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48965218 | rs1566816 | C | T | rs1566816 | 21909107 | 9.90E-09 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48966363 | rs1995620 | G | A | rs1995620 | 21909107 | 5.50E-04 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48967332 | rs1506523 | G | A | rs1506523 | 21909107 | 2.00E-08 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48968413 | rs10851469 | C | T | rs10851469 | 21909107 | 1.30E-08 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48970280 | rs10851470 | G | A | rs10851470 | 21909107 | 3.00E-08 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48973897 | rs8038940 | G | A | rs8038940 | 21909107 | 2.10E-08 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48984446 | rs2045889 | T | A | rs2045889 | 21909107 | 1.50E-08 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48984822 | rs12907144 | A | G | rs12907144 | 21909107 | 9.20E-09 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48987719 | rs2045891 | C | T | rs2045891 | 21909107 | 1.40E-08 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48988044 | rs2126905 | C | T | rs2126905 | 21909107 | 7.50E-09 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 15 | 48988951 | rs12910178 | C | T | rs12910178 | 21909107 | 7.70E-09 | NA | NA | NA | 765 European ancestry cases; 874 European ancestry controls | European(1639) | ALL(1639) | EUR(1639) | ALL(1639) | Thoracic aortic aneurysms and dissections | HPOID:0004942 | Aortic aneurysm | DOID:14004 | thoracic aortic aneurysm | D017545 | Aortic Aneurysm, Thoracic | EFOID:0004282 | thoracic aortic aneurysm | Aortic aneurysm | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
Mapped by lexical matching(Total Items:0) |
|---|
| (Waiting for update.) |
Mapped by homologous gene(Total Items:0) |
|---|
| (Waiting for update.) |
| Disease ID | 415 |
|---|---|
| Disease | thoracic aortic aneurysm |
| Case | (Waiting for update.) |