eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| testicular seminoma | ||||
| Disease ID | 863 |
|---|---|
| Disease | testicular seminoma |
| Definition | A radiosensitive, malignant neoplasm of the testis, thought to be derived from primordial germ cells of the sexually undifferentiated embryonic gonad. There are three variants: classical (typical), the most common type; anaplastic; and spermatocytic. The classical seminoma is composed of fairly well differentiated sheets or cords of uniform polygonal or round cells (seminoma cells), each cell having abundant clear cytoplasm, distinct cell membranes, a centrally placed round nucleus, and one or more nucleoli. In the female, a grossly and histologically identical neoplasm, known as dysgerminoma, occurs. (Dorland, 27th ed) |
| Synonym | [m]seminoma nos [m]seminoma nos (morphologic abnormality) [m]seminomas [m]seminomas (morphologic abnormality) seminoma seminoma (disorder) seminoma (morphologic abnormality) seminoma [disease/finding] seminoma of testis seminoma of testis (disorder) seminoma of the testis seminoma testicular cancer seminoma testis seminoma, malignant seminoma, no icd-o subtype seminoma, no icd-o subtype (morphologic abnormality) seminoma, no international classification of diseases for oncology subtype seminoma, no international classification of diseases for oncology subtype (morphologic abnormality) seminoma, nos seminoma, pure seminoma, testicular seminomas testicle cancer, seminoma testicular cancer, seminoma testicular seminoma pure testis cancer, seminoma testis, seminoma |
| Orphanet | |
| DOID | |
| UMLS | C0036631 |
| MeSH | |
| SNOMED-CT | |
| Comorbidity | UMLS | Disease | Sentences' Count(Total Sentences:23) C0039590 | testicular cancer | 3 C0010417 | undescended testis | 3 C0206695 | neuroendocrine carcinoma | 2 C0206659 | embryonal carcinoma | 2 C0039538 | teratoma | 2 C0039538 | teratomas | 2 C0036202 | sarcoidosis | 1 C0007099 | carcinoma in situ | 1 C0206660 | germinoma | 1 C0021845 | bowel perforation | 1 C0007133 | papillary carcinoma | 1 C0494165 | hepatic metastasis | 1 C0020437 | hypercalcemia | 1 C0039585 | androgen insensitivity syndrome | 1 C1261473 | sarcomas | 1 C0018051 | gonadal dysgenesis | 1 C0014038 | encephalitis | 1 C0019163 | hepatitis b | 1 C0020538 | hypertension | 1 C0020541 | portal hypertension | 1 C1261473 | sarcoma | 1 C0206695 | neuroendocrine carcinomas | 1 C0014145 | yolk sac tumor | 1 |
| Curated Gene | Entrez_id | Symbol | Resource(Total Genes:3) |
| Inferring Gene | (Waiting for update.) |
| Text Mined Gene | Entrez_id | Symbol | Score | Resource(Total Genes:150) 91 | ACVR1B | 2.102 | DISEASES 93 | ACVR2B | 1.902 | DISEASES 174 | AFP | 5.745 | DISEASES 57491 | AHRR | 1.705 | DISEASES 50808 | AK3 | 2.005 | DISEASES 205 | AK4 | 1.601 | DISEASES 249 | ALPL | 1.338 | DISEASES 250 | ALPP | 3.615 | DISEASES 196527 | ANO6 | 1.712 | DISEASES 160 | AP2A1 | 2.735 | DISEASES 317 | APAF1 | 1.013 | DISEASES 367 | AR | 1.702 | DISEASES 369 | ARAF | 1.011 | DISEASES 419 | ART3 | 2.187 | DISEASES 578 | BAK1 | 2.662 | DISEASES 768 | CA9 | 1.844 | DISEASES 8558 | CDK10 | 1.867 | DISEASES 1029 | CDKN2A | 1.105 | DISEASES 1032 | CDKN2D | 2.087 | DISEASES 1058 | CENPA | 1.074 | DISEASES 94027 | CGB7 | 1.092 | DISEASES 94115 | CGB8 | 2.513 | DISEASES 9074 | CLDN6 | 1.451 | DISEASES 728577 | CNTNAP3B | 2.703 | DISEASES 1443 | CSH2 | 2.622 | DISEASES 541466 | CT45A1 | 2.623 | DISEASES 1485 | CTAG1B | 1.971 | DISEASES 1617 | DAZ1 | 1.138 | DISEASES 8653 | DDX3Y | 1.554 | DISEASES 54514 | DDX4 | 1.855 | DISEASES 1761 | DMRT1 | 3.349 | DISEASES 123872 | DNAAF1 | 2.195 | DISEASES 1789 | DNMT3B | 2.668 | DISEASES 359787 | DPPA3 | 3.407 | DISEASES 1812 | DRD1 | 1.598 | DISEASES 1832 | DSP | 1.175 | DISEASES 8663 | EIF3C | 2.343 | DISEASES 955 | ENTPD6 | 2.849 | DISEASES 405754 | ERVFRD-1 | 2.17 | DISEASES 30816 | ERVW-1 | 1.068 | DISEASES 2100 | ESR2 | 2.521 | DISEASES 2103 | ESRRB | 1.181 | DISEASES 346653 | FAM71F2 | 4.155 | DISEASES 356 | FASLG | 1.037 | DISEASES 2261 | FGFR3 | 1.969 | DISEASES 668 | FOXL2 | 1.197 | DISEASES 122786 | FRMD6 | 1.345 | DISEASES 2526 | FUT4 | 1.316 | DISEASES 2543 | GAGE1 | 1.543 | DISEASES 645073 | GAGE12G | 1.942 | DISEASES 2576 | GAGE4 | 1.538 | DISEASES 2591 | GALNT3 | 1.207 | DISEASES 2650 | GCNT1 | 1.401 | DISEASES 9573 | GDF3 | 3.166 | DISEASES 2668 | GDNF | 1.795 | DISEASES 2674 | GFRA1 | 3.038 | DISEASES 199720 | GGN | 2.1 | DISEASES 2689 | GH2 | 1.103 | DISEASES 10755 | GIPC1 | 1.31 | DISEASES 2719 | GPC3 | 2.004 | DISEASES 11245 | GPR176 | 1.186 | DISEASES 2886 | GRB7 | 2.741 | DISEASES 3105 | HLA-A | 1.312 | DISEASES 3161 | HMMR | 1.587 | DISEASES 3292 | HSD17B1 | 1.628 | DISEASES 3295 | HSD17B4 | 1.886 | DISEASES 3481 | IGF2 | 1.675 | DISEASES 3483 | IGFALS | 1.585 | DISEASES 3621 | ING1 | 1.032 | DISEASES 3640 | INSL3 | 1.701 | DISEASES 9371 | KIF3B | 2.041 | DISEASES 3833 | KIFC1 | 1.551 | DISEASES 3831 | KLC1 | 1.169 | DISEASES 8564 | KMO | 1.136 | DISEASES 3875 | KRT18 | 1.094 | DISEASES 3855 | KRT7 | 1.316 | DISEASES 8649 | LAMTOR3 | 2.15 | DISEASES 3939 | LDHA | 1.53 | DISEASES 51213 | LUZP4 | 1.887 | DISEASES 4100 | MAGEA1 | 2.166 | DISEASES 4101 | MAGEA2 | 1.134 | DISEASES 266740 | MAGEA2B | 1.136 | DISEASES 4102 | MAGEA3 | 2.031 | DISEASES 51438 | MAGEC2 | 2.394 | DISEASES 728239 | MAGED4 | 2.058 | DISEASES 4133 | MAP2 | 1.079 | DISEASES 4190 | MDH1 | 1.428 | DISEASES 196410 | METTL7B | 1.511 | DISEASES 4601 | MXI1 | 1.207 | DISEASES 4609 | MYC | 1.08 | DISEASES 339345 | NANOS2 | 2.672 | DISEASES 342977 | NANOS3 | 3.321 | DISEASES 4700 | NDUFA6 | 1.419 | DISEASES 199713 | NLRP7 | 1.44 | DISEASES 2516 | NR5A1 | 1.218 | DISEASES 56001 | NXF2 | 1.859 | DISEASES 728343 | NXF2B | 1.859 | DISEASES 7849 | PAX8 | 1.801 | DISEASES 5214 | PFKP | 1.283 | DISEASES 55124 | PIWIL2 | 1.029 | DISEASES 10687 | PNMA2 | 2.837 | DISEASES 5420 | PODXL | 1.465 | DISEASES 5450 | POU2AF1 | 1.155 | DISEASES 23532 | PRAME | 1.535 | DISEASES 639 | PRDM1 | 3.013 | DISEASES 29122 | PRSS50 | 1.595 | DISEASES 5788 | PTPRC | 1.592 | DISEASES 57111 | RAB25 | 1.275 | DISEASES 116442 | RAB39B | 1.766 | DISEASES 5884 | RAD17 | 1.306 | DISEASES 11186 | RASSF1 | 1.218 | DISEASES 378949 | RBMY1D | 2.37 | DISEASES 7732 | RNF112 | 2.014 | DISEASES 165918 | RNF168 | 1.633 | DISEASES 56254 | RNF20 | 1.838 | DISEASES 55511 | SAGE1 | 2.926 | DISEASES 6392 | SDHD | 1.013 | DISEASES 5265 | SERPINA1 | 1.337 | DISEASES 26503 | SLC17A5 | 2.669 | DISEASES 144195 | SLC2A14 | 1.172 | DISEASES 23583 | SMUG1 | 3.617 | DISEASES 6657 | SOX2 | 3.65 | DISEASES 30014 | SPANXA1 | 2.854 | DISEASES 64648 | SPANXD | 2.528 | DISEASES 353324 | SPATA12 | 3.252 | DISEASES 10253 | SPRY2 | 1.038 | DISEASES 81848 | SPRY4 | 3.182 | DISEASES 6736 | SRY | 2.167 | DISEASES 727837 | SSX2B | 1.323 | DISEASES 56910 | STARD7 | 2 | DISEASES 3925 | STMN1 | 2.318 | DISEASES 6847 | SYCP1 | 1.886 | DISEASES 6996 | TDG | 1.062 | DISEASES 732253 | TDRG1 | 4.284 | DISEASES 7004 | TEAD4 | 2.613 | DISEASES 83659 | TEKT1 | 2.893 | DISEASES 80312 | TET1 | 1.204 | DISEASES 51270 | TFDP3 | 1.134 | DISEASES 7163 | TPD52 | 1.056 | DISEASES 1787 | TRDMT1 | 1.657 | DISEASES 7258 | TSPY1 | 3.392 | DISEASES 100289087 | TSPY10 | 3.428 | DISEASES 7259 | TSPYL1 | 2.363 | DISEASES 54970 | TTC12 | 1.847 | DISEASES 7405 | UVRAG | 1.331 | DISEASES 7422 | VEGFA | 1.166 | DISEASES 7490 | WT1 | 2.149 | DISEASES 54739 | XAF1 | 1.06 | DISEASES 23414 | ZFPM2 | 1.133 | DISEASES 6940 | ZNF354A | 3.236 | DISEASES |
| Locus | (Waiting for update.) |
| Disease ID | 863 |
|---|---|
| Disease | testicular seminoma |
| Integrated Phenotype | (Waiting for update.) |
| Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:19) HP:0002664 | Neoplasia | 16 HP:0000028 | Cryptorchidism | 7 HP:0030731 | Carcinoma | 5 HP:0009792 | Teratoma | 2 HP:0010788 | Testicular neoplasm | 2 HP:0000016 | Urinary retention | 1 HP:0000133 | Mixed gonadal dysgenesis | 1 HP:0008689 | Bilateral cryptorchidism | 1 HP:0008668 | 46,xy gonadal dysgenesis | 1 HP:0003072 | Hypercalcemia | 1 HP:0100242 | Sarcoma | 1 HP:0002383 | Encephalitis | 1 HP:0010459 | True hermaphroditism | 1 HP:0000822 | Hypertension | 1 HP:0002729 | Follicular hyperplasia | 1 HP:0001945 | Fever | 1 HP:0001409 | Portal hypertension | 1 HP:0002835 | Aspiration | 1 HP:0100620 | Germinoma | 1 |
| Disease ID | 863 |
|---|---|
| Disease | testicular seminoma |
| Manually Symptom | UMLS | Name(Total Manually Symptoms:9) |
| Text Mined Symptom | UMLS | Name | Sentences' Count(Total Symptoms:4) C0205851 | germ cell tumors | 2 C0020437 | hypercalcemia | 1 C0030472 | paraneoplastic syndrome | 1 C0153685 | renal metastasis | 1 |
Manually Genotype(Total Text Mining Genotypes:0) |
|---|
| (Waiting for update.) |
Text Mining Genotype(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
All Snps(Total Genotypes:5) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| snpId | pubmedId | geneId | geneSymbol | diseaseId | sourceId | sentence | score | Year | geneSymbol_dbSNP | CHROMOSOME | POS | REF | ALT |
| rs7371084 | 22245602 | 2099 | ESR1 | umls:C0036631 | BeFree | Polymorphisms in ESR1 (rs9397080; OR=1.85, 95% CI: 1.18-2.91) and LHCGR (rs7371084; OR=2.37, 95% CI: 1.26-4.49) associated with risk of seminoma and metastasis, respectively. | 0.000542884 | 2012 | LHCGR;STON1-GTF2A1L | 2 | 48712814 | T | C |
| rs7371084 | 22245602 | 3973 | LHCGR | umls:C0036631 | BeFree | Polymorphisms in ESR1 (rs9397080; OR=1.85, 95% CI: 1.18-2.91) and LHCGR (rs7371084; OR=2.37, 95% CI: 1.26-4.49) associated with risk of seminoma and metastasis, respectively. | 0.000271442 | 2012 | LHCGR;STON1-GTF2A1L | 2 | 48712814 | T | C |
| rs78311289 | 19855393 | 3265 | HRAS | umls:C0036631 | BeFree | Screening of 30 spermatocytic seminomas for oncogenic mutations in 17 genes identified 2 mutations in FGFR3 (both 1948A>G, encoding K650E, which causes thanatophoric dysplasia in the germline) and 5 mutations in HRAS. | 0.120271442 | 2009 | FGFR3 | 4 | 1806162 | A | C,G |
| rs9397080 | 22245602 | 3973 | LHCGR | umls:C0036631 | BeFree | Polymorphisms in ESR1 (rs9397080; OR=1.85, 95% CI: 1.18-2.91) and LHCGR (rs7371084; OR=2.37, 95% CI: 1.26-4.49) associated with risk of seminoma and metastasis, respectively. | 0.000271442 | 2012 | ESR1 | 6 | 152059380 | C | T |
| rs9397080 | 22245602 | 2099 | ESR1 | umls:C0036631 | BeFree | Polymorphisms in ESR1 (rs9397080; OR=1.85, 95% CI: 1.18-2.91) and LHCGR (rs7371084; OR=2.37, 95% CI: 1.26-4.49) associated with risk of seminoma and metastasis, respectively. | 0.000542884 | 2012 | ESR1 | 6 | 152059380 | C | T |
GWASdb Annotation(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:95) | |||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CHR | POS | SNPID | REF | ALT | ORI_SNPID | PMID | P_VALUE | P_VALUE_TEXT | OR/BETA | CI95_TEXT | GWAS_INITIAL_SAMPLE_SIZE | SUB_POPULATION | SUPER_POPULATION | GWAS_TRAIT | HPO_ID | HPO_TERM | DO_ID | DO_TERM | MESH_ID | MESH_TERM | EFO_ID | EFO_TERM | DOLITE_TERM | RISK_ALLELE | PUBLICATION_TYPE | AA | GENE_SYMBOL | TYPE | REFGENE |
| 1 | 156169610 | rs2072499 | A | G | rs2072499 | 23666240 | 3.00E-08 | NA | 1.19 | [1.08-1.30] | 986 European ancestry cases; 4,946 European ancestry controls | European(5932) | ALL(5932) | EUR(5932) | ALL(5932) | Testicular germ cell tumor | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D009373 | Neoplasms, Germ Cell and Embryonal | EFOID:0005088 | testicular carcinoma | Testicular tumor | rs2072499-G | Meta-Analysis | Research Support, Non-U.S. Gov't | C |
| 1 | 165831649 | rs4657482 | A | G | rs4657482 | 19483681 | 2.00E-06 | NA | 1.14 | [0.99-1.31] | 730 cases; 1,435 controls | NOPOP(2165) | ALL(2165) | NOPOP(2165) | ALL(2165) | Testicular germ cell tumor | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D009373 | Neoplasms, Germ Cell and Embryonal | EFOID:0005088 | testicular carcinoma | Testicular tumor | rs4657482-A | Research Support, Non-U.S. Gov't | G | UCK2 |
| 1 | 165831649 | rs4657482 | A | G | rs4657482 | 23666239 | 6.00E-06 | NA | 1.43 | [1.22-1.67] | 582 European ancestry male cases; 1,056 European ancestry male controls | European(1638) | ALL(1638) | EUR(1638) | ALL(1638) | Testicular germ cell tumor | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D009373 | Neoplasms, Germ Cell and Embryonal | EFOID:0005088 | testicular carcinoma | Testicular tumor | rs4657482-A | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 1 | 165873392 | rs3790672 | T | C | rs3790672 | 23666240 | 2.00E-08 | NA | 1.2 | [1.09-1.33] | 986 European ancestry cases; 4,946 European ancestry controls | European(5932) | ALL(5932) | EUR(5932) | ALL(5932) | Testicular germ cell tumor | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D009373 | Neoplasms, Germ Cell and Embryonal | EFOID:0005088 | testicular carcinoma | Testicular tumor | rs3790672-C | Meta-Analysis | Research Support, Non-U.S. Gov't | T |
| 3 | 16625048 | rs10510452 | A | G | rs10510452 | 23666240 | 1.00E-08 | NA | 1.24 | [1.12-1.37] | 986 European ancestry cases; 4,946 European ancestry controls | European(5932) | ALL(5932) | EUR(5932) | ALL(5932) | Testicular germ cell tumor | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D009373 | Neoplasms, Germ Cell and Embryonal | EFOID:0005088 | testicular carcinoma | Testicular tumor | rs10510452-A | Meta-Analysis | Research Support, Non-U.S. Gov't | A |
| 4 | 95224812 | rs17021463 | T | G | rs17021463 | 23666239 | 1.00E-08 | NA | 1.19 | [1.12-1.26] | 582 European ancestry male cases; 1,056 European ancestry male controls | European(1638) | ALL(1638) | EUR(1638) | ALL(1638) | Testicular germ cell tumor | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D009373 | Neoplasms, Germ Cell and Embryonal | EFOID:0005088 | testicular carcinoma | Testicular tumor | rs17021463-T | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 4 | 104054686 | rs2720460 | A | G | rs2720460 | 23666240 | 2.00E-10 | NA | 1.24 | [1.12-1.36] | 986 European ancestry cases; 4,946 European ancestry controls | European(5932) | ALL(5932) | EUR(5932) | ALL(5932) | Testicular germ cell tumor | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D009373 | Neoplasms, Germ Cell and Embryonal | EFOID:0005088 | testicular carcinoma | Testicular tumor | rs2720460-A | Meta-Analysis | Research Support, Non-U.S. Gov't | G |
| 4 | 104137790 | rs4699052 | C | T | rs4699052 | 19483681 | 2.00E-07 | NA | 1.21 | [1.05-1.39] | 730 cases; 1,435 controls | NOPOP(2165) | ALL(2165) | NOPOP(2165) | ALL(2165) | Testicular germ cell tumor | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D009373 | Neoplasms, Germ Cell and Embryonal | EFOID:0005088 | testicular carcinoma | Testicular tumor | rs4699052-C | Research Support, Non-U.S. Gov't | T | NA |
| 5 | 1279790 | rs10069690 | C | T | rs10069690 | 20543847 | 3.71E-08 | NA | NA | NA | 979 European ancestry cases; 4,947 European ancestry controls | European(5926) | ALL(5926) | EUR(5926) | ALL(5926) | Testicular germ cell cancer | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, Non-U.S. Gov't | T | TERT |
| 5 | 1286516 | rs2736100 | C | A | rs2736100 | 20543847 | 8.00E-15 | NA | 1.33 | [1.18-1.50] | 979 European ancestry cases; 4,947 European ancestry controls | European(5926) | ALL(5926) | EUR(5926) | ALL(5926) | Testicular germ cell cancer | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | rs2736100-T | Research Support, Non-U.S. Gov't | T | TERT |
| 5 | 1286516 | rs2736100 | C | A | rs2736100 | 23666239 | 4.82E-05 | NA | 1.37 | [1.77-1.58] | 582 European ancestry male cases; 1,056 European ancestry male controls | European(1638) | ALL(1638) | EUR(1638) | ALL(1638) | Testicular germ cell tumor | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D009373 | Neoplasms, Germ Cell and Embryonal | EFOID:0005088 | testicular carcinoma | Testicular tumor | rs2736100-G | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 5 | 1286516 | rs2736100 | C | A | rs2736100 | 23666240 | 6.12E-18 | NA | 1.32 | [1.20-1.45] | 986 European ancestry cases; 4,946 European ancestry controls | European(5932) | ALL(5932) | EUR(5932) | ALL(5932) | Testicular germ cell tumor | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D009373 | Neoplasms, Germ Cell and Embryonal | EFOID:0005088 | testicular carcinoma | Testicular tumor | rs2736100-G | Meta-Analysis | Research Support, Non-U.S. Gov't | T |
| 5 | 1288547 | rs2853676 | T | C | rs2853676 | 20543847 | 6.18E-07 | NA | NA | NA | 979 European ancestry cases; 4,947 European ancestry controls | European(5926) | ALL(5926) | EUR(5926) | ALL(5926) | Testicular germ cell cancer | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, Non-U.S. Gov't | G | TERT |
| 5 | 1294086 | rs2736098 | C | T | rs2736098 | 20543847 | 2.21E-06 | NA | NA | NA | 979 European ancestry cases; 4,947 European ancestry controls | European(5926) | ALL(5926) | EUR(5926) | ALL(5926) | Testicular germ cell cancer | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, Non-U.S. Gov't | G | TERT |
| 5 | 1308552 | rs4635969 | G | A | rs4635969 | 20543847 | 1.00E-23 | NA | 1.54 | [1.33-1.79] | 979 European ancestry cases; 4,947 European ancestry controls | European(5926) | ALL(5926) | EUR(5926) | ALL(5926) | Testicular germ cell cancer | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | rs4635969-T | Research Support, Non-U.S. Gov't | C | NA |
| 5 | 1308552 | rs4635969 | G | A | rs4635969 | 23666239 | 2.22E-04 | NA | 1.4 | [1.17-1.68] | 582 European ancestry male cases; 1,056 European ancestry male controls | European(1638) | ALL(1638) | EUR(1638) | ALL(1638) | Testicular germ cell tumor | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D009373 | Neoplasms, Germ Cell and Embryonal | EFOID:0005088 | testicular carcinoma | Testicular tumor | rs4635969-T | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 5 | 1308552 | rs4635969 | G | A | rs4635969 | 23666240 | 5.00E-24 | NA | 1.39 | [1.25-1.54] | 986 European ancestry cases; 4,946 European ancestry controls | European(5932) | ALL(5932) | EUR(5932) | ALL(5932) | Testicular germ cell tumor | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D009373 | Neoplasms, Germ Cell and Embryonal | EFOID:0005088 | testicular carcinoma | Testicular tumor | rs4635969-T | Meta-Analysis | Research Support, Non-U.S. Gov't | C |
| 5 | 1315343 | rs4975615 | G | A | rs4975615 | 20543847 | 2.50E-08 | NA | NA | NA | 979 European ancestry cases; 4,947 European ancestry controls | European(5926) | ALL(5926) | EUR(5926) | ALL(5926) | Testicular germ cell cancer | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, Non-U.S. Gov't | A | NA |
| 5 | 1315660 | rs4975616 | G | A | rs4975616 | 20543847 | 5.91E-07 | NA | NA | NA | 979 European ancestry cases; 4,947 European ancestry controls | European(5926) | ALL(5926) | EUR(5926) | ALL(5926) | Testicular germ cell cancer | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, Non-U.S. Gov't | G | NA |
| 5 | 1319680 | rs451360 | C | A | rs451360 | 20543847 | 1.16E-15 | NA | NA | NA | 979 European ancestry cases; 4,947 European ancestry controls | European(5926) | ALL(5926) | EUR(5926) | ALL(5926) | Testicular germ cell cancer | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, Non-U.S. Gov't | G | CLPTM1L |
| 5 | 1320136 | rs421629 | G | A | rs421629 | 20543847 | 7.44E-07 | NA | NA | NA | 979 European ancestry cases; 4,947 European ancestry controls | European(5926) | ALL(5926) | EUR(5926) | ALL(5926) | Testicular germ cell cancer | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, Non-U.S. Gov't | T | CLPTM1L |
| 5 | 1320247 | rs380286 | G | A | rs380286 | 20543847 | 7.44E-07 | NA | NA | NA | 979 European ancestry cases; 4,947 European ancestry controls | European(5926) | ALL(5926) | EUR(5926) | ALL(5926) | Testicular germ cell cancer | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, Non-U.S. Gov't | A | CLPTM1L |
| 5 | 1322087 | rs401681 | C | T | rs401681 | 20543847 | 4.24E-22 | NA | NA | NA | 979 European ancestry cases; 4,947 European ancestry controls | European(5926) | ALL(5926) | EUR(5926) | ALL(5926) | Testicular germ cell cancer | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, Non-U.S. Gov't | T | CLPTM1L |
| 5 | 1325767 | rs466502 | A | G | rs466502 | 20543847 | 3.08E-07 | NA | NA | NA | 979 European ancestry cases; 4,947 European ancestry controls | European(5926) | ALL(5926) | EUR(5926) | ALL(5926) | Testicular germ cell cancer | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, Non-U.S. Gov't | T | CLPTM1L |
| 5 | 1325803 | rs465498 | A | G | rs465498 | 20543847 | 7.48E-07 | NA | NA | NA | 979 European ancestry cases; 4,947 European ancestry controls | European(5926) | ALL(5926) | EUR(5926) | ALL(5926) | Testicular germ cell cancer | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, Non-U.S. Gov't | C | CLPTM1L |
| 5 | 1330253 | rs452932 | T | C | rs452932 | 20543847 | 7.44E-07 | NA | NA | NA | 979 European ancestry cases; 4,947 European ancestry controls | European(5926) | ALL(5926) | EUR(5926) | ALL(5926) | Testicular germ cell cancer | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, Non-U.S. Gov't | G | CLPTM1L |
| 5 | 1330840 | rs452384 | T | C | rs452384 | 20543847 | 7.48E-07 | NA | NA | NA | 979 European ancestry cases; 4,947 European ancestry controls | European(5926) | ALL(5926) | EUR(5926) | ALL(5926) | Testicular germ cell cancer | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, Non-U.S. Gov't | G | CLPTM1L |
| 5 | 1336221 | rs467095 | T | C | rs467095 | 20543847 | 7.49E-07 | NA | NA | NA | 979 European ancestry cases; 4,947 European ancestry controls | European(5926) | ALL(5926) | EUR(5926) | ALL(5926) | Testicular germ cell cancer | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, Non-U.S. Gov't | G | CLPTM1L |
| 5 | 1337906 | rs31484 | A | T | rs31484 | 20543847 | 7.48E-07 | NA | NA | NA | 979 European ancestry cases; 4,947 European ancestry controls | European(5926) | ALL(5926) | EUR(5926) | ALL(5926) | Testicular germ cell cancer | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, Non-U.S. Gov't | T | CLPTM1L |
| 5 | 1342714 | rs31489 | C | A | rs31489 | 20543847 | 3.27E-08 | NA | NA | NA | 979 European ancestry cases; 4,947 European ancestry controls | European(5926) | ALL(5926) | EUR(5926) | ALL(5926) | Testicular germ cell cancer | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, Non-U.S. Gov't | C | CLPTM1L |
| 5 | 1344458 | rs31490 | G | A | rs31490 | 20543847 | 3.05E-07 | NA | NA | NA | 979 European ancestry cases; 4,947 European ancestry controls | European(5926) | ALL(5926) | EUR(5926) | ALL(5926) | Testicular germ cell cancer | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, Non-U.S. Gov't | G | CLPTM1L |
| 5 | 1346303 | rs27070 | G | C | rs27070 | 20543847 | 8.03E-09 | NA | NA | NA | 979 European ancestry cases; 4,947 European ancestry controls | European(5926) | ALL(5926) | EUR(5926) | ALL(5926) | Testicular germ cell cancer | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, Non-U.S. Gov't | A | NA |
| 5 | 134366200 | rs3805663 | A | G | rs3805663 | 23666240 | 2.00E-08 | NA | 1.25 | [1.13-1.38] | 986 European ancestry cases; 4,946 European ancestry controls | European(5932) | ALL(5932) | EUR(5932) | ALL(5932) | Testicular germ cell tumor | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D009373 | Neoplasms, Germ Cell and Embryonal | EFOID:0005088 | testicular carcinoma | Testicular tumor | rs3805663-T | Meta-Analysis | Research Support, Non-U.S. Gov't | G |
| 5 | 141656556 | rs11167772 | T | C | rs11167772 | 20543847 | 1.50E-11 | NA | NA | NA | 979 European ancestry cases; 4,947 European ancestry controls | European(5926) | ALL(5926) | EUR(5926) | ALL(5926) | Testicular germ cell cancer | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, Non-U.S. Gov't | C | NA |
| 5 | 141660464 | rs4912837 | C | T | rs4912837 | 20543847 | 6.79E-13 | NA | NA | NA | 979 European ancestry cases; 4,947 European ancestry controls | European(5926) | ALL(5926) | EUR(5926) | ALL(5926) | Testicular germ cell cancer | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, Non-U.S. Gov't | C | NA |
| 5 | 141669507 | rs4324715 | C | T | rs4324715 | 23666239 | 1.42E-07 | NA | 1.59 | [1.33-1.89] | 582 European ancestry male cases; 1,056 European ancestry male controls | European(1638) | ALL(1638) | EUR(1638) | ALL(1638) | Testicular germ cell tumor | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D009373 | Neoplasms, Germ Cell and Embryonal | EFOID:0005088 | testicular carcinoma | Testicular tumor | rs4324715-C | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 5 | 141681788 | rs4624820 | G | A | rs4624820 | 19483681 | 3.00E-13 | NA | 1.37 | [1.19-1.58] | 730 cases; 1,435 controls | NOPOP(2165) | ALL(2165) | NOPOP(2165) | ALL(2165) | Testicular germ cell tumor | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D009373 | Neoplasms, Germ Cell and Embryonal | EFOID:0005088 | testicular carcinoma | Testicular tumor | rs4624820-A | Research Support, Non-U.S. Gov't | G | NA |
| 5 | 141681788 | rs4624820 | G | A | rs4624820 | 20543847 | 1.00E-14 | NA | 1.47 | [1.33-1.64] | 979 European ancestry cases; 4,947 European ancestry controls | European(5926) | ALL(5926) | EUR(5926) | ALL(5926) | Testicular germ cell cancer | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, Non-U.S. Gov't | G | NA |
| 5 | 141681788 | rs4624820 | G | A | rs4624820 | 23666239 | 8.00E-10 | NA | 1.64 | [1.39-1.89] | 582 European ancestry male cases; 1,056 European ancestry male controls | European(1638) | ALL(1638) | EUR(1638) | ALL(1638) | Testicular germ cell tumor | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D009373 | Neoplasms, Germ Cell and Embryonal | EFOID:0005088 | testicular carcinoma | Testicular tumor | rs4624820-G | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 5 | 141681788 | rs4624820 | G | A | rs4624820 | 23666240 | 3.00E-31 | NA | 1.52 | [1.38-1.67] | 986 European ancestry cases; 4,946 European ancestry controls | European(5932) | ALL(5932) | EUR(5932) | ALL(5932) | Testicular germ cell tumor | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D009373 | Neoplasms, Germ Cell and Embryonal | EFOID:0005088 | testicular carcinoma | Testicular tumor | rs4624820-A | Meta-Analysis | Research Support, Non-U.S. Gov't | G |
| 5 | 141707606 | rs959662 | A | G | rs959662 | 20543847 | 4.97E-08 | NA | NA | NA | 979 European ancestry cases; 4,947 European ancestry controls | European(5926) | ALL(5926) | EUR(5926) | ALL(5926) | Testicular germ cell cancer | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, Non-U.S. Gov't | A | NA |
| 6 | 33541719 | rs513349 | A | G | rs513349 | 20543847 | 1.16E-08 | NA | NA | NA | 979 European ancestry cases; 4,947 European ancestry controls | European(5926) | ALL(5926) | EUR(5926) | ALL(5926) | Testicular germ cell cancer | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, Non-U.S. Gov't | G | BAK1 |
| 6 | 33542538 | rs210138 | A | G | rs210138 | 19483681 | 1.00E-13 | NA | 1.5 | [1.28-1.75] | 730 cases; 1,435 controls | NOPOP(2165) | ALL(2165) | NOPOP(2165) | ALL(2165) | Testicular germ cell tumor | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D009373 | Neoplasms, Germ Cell and Embryonal | EFOID:0005088 | testicular carcinoma | Testicular tumor | rs210138-G | Research Support, Non-U.S. Gov't | G | BAK1 |
| 6 | 33542538 | rs210138 | A | G | rs210138 | 20543847 | 3.77E-12 | NA | NA | NA | 979 European ancestry cases; 4,947 European ancestry controls | European(5926) | ALL(5926) | EUR(5926) | ALL(5926) | Testicular germ cell cancer | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, Non-U.S. Gov't | G | BAK1 |
| 6 | 33542538 | rs210138 | A | G | rs210138 | 23666239 | 3.00E-07 | NA | 1.62 | [1.35-1.95] | 582 European ancestry male cases; 1,056 European ancestry male controls | European(1638) | ALL(1638) | EUR(1638) | ALL(1638) | Testicular germ cell tumor | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D009373 | Neoplasms, Germ Cell and Embryonal | EFOID:0005088 | testicular carcinoma | Testicular tumor | rs210138-G | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 6 | 33542538 | rs210138 | A | G | rs210138 | 23666240 | 2.00E-24 | NA | 1.44 | [1.30-1.61] | 986 European ancestry cases; 4,946 European ancestry controls | European(5932) | ALL(5932) | EUR(5932) | ALL(5932) | Testicular germ cell tumor | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D009373 | Neoplasms, Germ Cell and Embryonal | EFOID:0005088 | testicular carcinoma | Testicular tumor | rs210138-G | Meta-Analysis | Research Support, Non-U.S. Gov't | G |
| 6 | 33543409 | rs210139 | A | C | rs210139 | 20543847 | 2.80E-14 | NA | NA | NA | 979 European ancestry cases; 4,947 European ancestry controls | European(5926) | ALL(5926) | EUR(5926) | ALL(5926) | Testicular germ cell cancer | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, Non-U.S. Gov't | A | BAK1 |
| 6 | 33557741 | rs375555 | T | C | rs375555 | 20543847 | 1.94E-12 | NA | NA | NA | 979 European ancestry cases; 4,947 European ancestry controls | European(5926) | ALL(5926) | EUR(5926) | ALL(5926) | Testicular germ cell cancer | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, Non-U.S. Gov't | T | LINC00336 |
| 6 | 33606523 | rs4713646 | C | T | rs4713646 | 20543847 | 2.41E-12 | NA | NA | NA | 979 European ancestry cases; 4,947 European ancestry controls | European(5926) | ALL(5926) | EUR(5926) | ALL(5926) | Testicular germ cell cancer | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, Non-U.S. Gov't | C,T | ITPR3 |
| 6 | 144446518 | rs7760281 | T | C | rs7760281 | 23666239 | 7.98E-04 | NA | 1.12 | [1.05-1.19] | 582 European ancestry male cases; 1,056 European ancestry male controls | European(1638) | ALL(1638) | EUR(1638) | ALL(1638) | Testicular germ cell tumor | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D009373 | Neoplasms, Germ Cell and Embryonal | EFOID:0005088 | testicular carcinoma | Testicular tumor | rs7760281- | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 7 | 1920826 | rs10275045 | C | T | rs10275045 | 23666239 | 3.78E-10 | NA | 1.2 | [1.13-1.27] | 582 European ancestry male cases; 1,056 European ancestry male controls | European(1638) | ALL(1638) | EUR(1638) | ALL(1638) | Testicular germ cell tumor | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D009373 | Neoplasms, Germ Cell and Embryonal | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 7 | 1968953 | rs12699477 | T | C | rs12699477 | 23666239 | 6.00E-09 | NA | 1.21 | [1.14-1.29] | 582 European ancestry male cases; 1,056 European ancestry male controls | European(1638) | ALL(1638) | EUR(1638) | ALL(1638) | Testicular germ cell tumor | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D009373 | Neoplasms, Germ Cell and Embryonal | EFOID:0005088 | testicular carcinoma | Testicular tumor | rs12699477-C | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 7 | 2172455 | rs3778991 | G | A | rs3778991 | 23666239 | 6.73E-10 | NA | 1.21 | [1.14-1.28] | 582 European ancestry male cases; 1,056 European ancestry male controls | European(1638) | ALL(1638) | EUR(1638) | ALL(1638) | Testicular germ cell tumor | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D009373 | Neoplasms, Germ Cell and Embryonal | EFOID:0005088 | testicular carcinoma | Testicular tumor | rs3778991- | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 8 | 70976505 | rs7010162 | C | T | rs7010162 | 23666240 | 5.00E-08 | NA | 1.22 | [1.11-1.34] | 986 European ancestry cases; 4,946 European ancestry controls | European(5932) | ALL(5932) | EUR(5932) | ALL(5932) | Testicular germ cell tumor | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D009373 | Neoplasms, Germ Cell and Embryonal | EFOID:0005088 | testicular carcinoma | Testicular tumor | rs7010162-G | Meta-Analysis | Research Support, Non-U.S. Gov't | C |
| 9 | 802801 | rs2370200 | A | G | rs2370200 | 20543847 | 7.91E-08 | NA | NA | NA | 979 European ancestry cases; 4,947 European ancestry controls | European(5926) | ALL(5926) | EUR(5926) | ALL(5926) | Testicular germ cell cancer | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, Non-U.S. Gov't | A | NA |
| 9 | 804436 | rs4742419 | T | C | rs4742419 | 20543847 | 2.78E-07 | NA | NA | NA | 979 European ancestry cases; 4,947 European ancestry controls | European(5926) | ALL(5926) | EUR(5926) | ALL(5926) | Testicular germ cell cancer | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, Non-U.S. Gov't | T,C | NA |
| 9 | 818693 | rs10815756 | T | C | rs10815756 | 20543847 | 3.05E-08 | NA | NA | NA | 979 European ancestry cases; 4,947 European ancestry controls | European(5926) | ALL(5926) | EUR(5926) | ALL(5926) | Testicular germ cell cancer | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, Non-U.S. Gov't | T | NA |
| 9 | 822594 | rs4141756 | T | C | rs4141756 | 20543847 | 2.08E-09 | NA | NA | NA | 979 European ancestry cases; 4,947 European ancestry controls | European(5926) | ALL(5926) | EUR(5926) | ALL(5926) | Testicular germ cell cancer | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, Non-U.S. Gov't | T | NA |
| 9 | 855091 | rs7029148 | A | G | rs7029148 | 20543847 | 1.48E-09 | NA | NA | NA | 979 European ancestry cases; 4,947 European ancestry controls | European(5926) | ALL(5926) | EUR(5926) | ALL(5926) | Testicular germ cell cancer | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, Non-U.S. Gov't | A | DMRT1 |
| 9 | 863635 | rs755383 | C | T | rs755383 | 20543847 | 1.00E-23 | NA | 1.37 | [1.21-1.55] | 979 European ancestry cases; 4,947 European ancestry controls | European(5926) | ALL(5926) | EUR(5926) | ALL(5926) | Testicular germ cell cancer | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | rs755383-T | Research Support, Non-U.S. Gov't | C | DMRT1 |
| 9 | 863635 | rs755383 | C | T | rs755383 | 23666239 | 4.00E-07 | NA | 1.52 | [1.30-1.79] | 582 European ancestry male cases; 1,056 European ancestry male controls | European(1638) | ALL(1638) | EUR(1638) | ALL(1638) | Testicular germ cell tumor | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D009373 | Neoplasms, Germ Cell and Embryonal | EFOID:0005088 | testicular carcinoma | Testicular tumor | rs755383-C | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 9 | 863635 | rs755383 | C | T | rs755383 | 23666240 | 2.00E-26 | NA | 1.38 | [1.25-1.52] | 986 European ancestry cases; 4,946 European ancestry controls | European(5932) | ALL(5932) | EUR(5932) | ALL(5932) | Testicular germ cell tumor | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D009373 | Neoplasms, Germ Cell and Embryonal | EFOID:0005088 | testicular carcinoma | Testicular tumor | rs755383-T | Meta-Analysis | Research Support, Non-U.S. Gov't | C |
| 12 | 14628069 | rs4346018 | A | G | rs4346018 | 20543847 | 3.20E-19 | NA | NA | NA | 979 European ancestry cases; 4,947 European ancestry controls | European(5926) | ALL(5926) | EUR(5926) | ALL(5926) | Testicular germ cell cancer | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, Non-U.S. Gov't | A | ATF7IP |
| 12 | 14653867 | rs2900333 | C | T | rs2900333 | 20543847 | 6.00E-10 | NA | 1.27 | [1.12-1.44] | 979 European ancestry cases; 4,947 European ancestry controls | European(5926) | ALL(5926) | EUR(5926) | ALL(5926) | Testicular germ cell cancer | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | rs2900333-C | Research Support, Non-U.S. Gov't | C | NA |
| 12 | 14653867 | rs2900333 | C | T | rs2900333 | 23666240 | 1.00E-13 | NA | 1.32 | [1.20-1.46] | 986 European ancestry cases; 4,946 European ancestry controls | European(5932) | ALL(5932) | EUR(5932) | ALL(5932) | Testicular germ cell tumor | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D009373 | Neoplasms, Germ Cell and Embryonal | EFOID:0005088 | testicular carcinoma | Testicular tumor | rs2900333-C | Meta-Analysis | Research Support, Non-U.S. Gov't | C |
| 12 | 88732585 | rs4842602 | C | T | rs4842602 | 20543847 | 9.43E-07 | NA | NA | NA | 979 European ancestry cases; 4,947 European ancestry controls | European(5926) | ALL(5926) | EUR(5926) | ALL(5926) | Testicular germ cell cancer | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, Non-U.S. Gov't | C | NA |
| 12 | 88811689 | rs4842610 | C | T | rs4842610 | 20543847 | 8.23E-10 | NA | NA | NA | 979 European ancestry cases; 4,947 European ancestry controls | European(5926) | ALL(5926) | EUR(5926) | ALL(5926) | Testicular germ cell cancer | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, Non-U.S. Gov't | C | NA |
| 12 | 88848006 | rs7974506 | A | G | rs7974506 | 20543847 | 7.18E-08 | NA | NA | NA | 979 European ancestry cases; 4,947 European ancestry controls | European(5926) | ALL(5926) | EUR(5926) | ALL(5926) | Testicular germ cell cancer | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, Non-U.S. Gov't | G | NA |
| 12 | 88865241 | rs11104896 | T | C | rs11104896 | 20543847 | 6.88E-07 | NA | NA | NA | 979 European ancestry cases; 4,947 European ancestry controls | European(5926) | ALL(5926) | EUR(5926) | ALL(5926) | Testicular germ cell cancer | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, Non-U.S. Gov't | C | NA |
| 12 | 88874179 | rs11104901 | G | T | rs11104901 | 20543847 | 2.31E-13 | NA | NA | NA | 979 European ancestry cases; 4,947 European ancestry controls | European(5926) | ALL(5926) | EUR(5926) | ALL(5926) | Testicular germ cell cancer | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, Non-U.S. Gov't | C | NA |
| 12 | 88890671 | rs995030 | A | G | rs995030 | 19483681 | 1.00E-31 | NA | 2.55 | [2.05-3.19] | 730 cases; 1,435 controls | NOPOP(2165) | ALL(2165) | NOPOP(2165) | ALL(2165) | Testicular germ cell tumor | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D009373 | Neoplasms, Germ Cell and Embryonal | EFOID:0005088 | testicular carcinoma | Testicular tumor | rs1508595-G | Research Support, Non-U.S. Gov't | A | KITLG |
| 12 | 88890671 | rs995030 | A | G | rs995030 | 19483681 | 3.00E-30 | NA | 2.69 | [2.10-3.44] | 730 cases; 1,435 controls | NOPOP(2165) | ALL(2165) | NOPOP(2165) | ALL(2165) | Testicular germ cell tumor | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D009373 | Neoplasms, Germ Cell and Embryonal | EFOID:0005088 | testicular carcinoma | Testicular tumor | rs1508595-G | Research Support, Non-U.S. Gov't | A | KITLG |
| 12 | 88890671 | rs995030 | A | G | rs995030 | 20543847 | 2.65E-12 | NA | NA | NA | 979 European ancestry cases; 4,947 European ancestry controls | European(5926) | ALL(5926) | EUR(5926) | ALL(5926) | Testicular germ cell cancer | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, Non-U.S. Gov't | A | KITLG |
| 12 | 88890671 | rs995030 | A | G | rs995030 | 23666239 | 3.00E-13 | NA | 2.33 | [1.85-2.94] | 582 European ancestry male cases; 1,056 European ancestry male controls | European(1638) | ALL(1638) | EUR(1638) | ALL(1638) | Testicular germ cell tumor | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D009373 | Neoplasms, Germ Cell and Embryonal | EFOID:0005088 | testicular carcinoma | Testicular tumor | rs995030-A | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 12 | 88890671 | rs995030 | A | G | rs995030 | 23666240 | 2.00E-50 | NA | 2.26 | [1.95-2.61] | 986 European ancestry cases; 4,946 European ancestry controls | European(5932) | ALL(5932) | EUR(5932) | ALL(5932) | Testicular germ cell tumor | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D009373 | Neoplasms, Germ Cell and Embryonal | EFOID:0005088 | testicular carcinoma | Testicular tumor | rs995030-G | Meta-Analysis | Research Support, Non-U.S. Gov't | A |
| 12 | 88904764 | rs11104911 | C | T | rs11104911 | 20543847 | 8.85E-25 | NA | NA | NA | 979 European ancestry cases; 4,947 European ancestry controls | European(5926) | ALL(5926) | EUR(5926) | ALL(5926) | Testicular germ cell cancer | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, Non-U.S. Gov't | T | KITLG |
| 12 | 88915835 | rs10777125 | G | A | rs10777125 | 20543847 | 6.66E-13 | NA | NA | NA | 979 European ancestry cases; 4,947 European ancestry controls | European(5926) | ALL(5926) | EUR(5926) | ALL(5926) | Testicular germ cell cancer | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, Non-U.S. Gov't | A | KITLG |
| 12 | 88918743 | rs1022034 | T | G | rs1022034 | 20543847 | 4.13E-11 | NA | NA | NA | 979 European ancestry cases; 4,947 European ancestry controls | European(5926) | ALL(5926) | EUR(5926) | ALL(5926) | Testicular germ cell cancer | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, Non-U.S. Gov't | A | KITLG |
| 12 | 88925973 | rs1492347 | T | C | rs1492347 | 20543847 | 2.29E-24 | NA | NA | NA | 979 European ancestry cases; 4,947 European ancestry controls | European(5926) | ALL(5926) | EUR(5926) | ALL(5926) | Testicular germ cell cancer | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, Non-U.S. Gov't | C | KITLG |
| 12 | 88932035 | rs10506956 | C | A | rs10506956 | 20543847 | 1.24E-10 | NA | NA | NA | 979 European ancestry cases; 4,947 European ancestry controls | European(5926) | ALL(5926) | EUR(5926) | ALL(5926) | Testicular germ cell cancer | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, Non-U.S. Gov't | A | KITLG |
| 12 | 88939133 | rs3782176 | A | G | rs3782176 | 20543847 | 1.29E-12 | NA | NA | NA | 979 European ancestry cases; 4,947 European ancestry controls | European(5926) | ALL(5926) | EUR(5926) | ALL(5926) | Testicular germ cell cancer | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, Non-U.S. Gov't | G | KITLG |
| 12 | 88953561 | rs3782181 | C | A | rs3782181 | 20543847 | 2.00E-26 | NA | 2.22 | [1.89-2.56] | 979 European ancestry cases; 4,947 European ancestry controls | European(5926) | ALL(5926) | EUR(5926) | ALL(5926) | Testicular germ cell cancer | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, Non-U.S. Gov't | C | KITLG |
| 12 | 88986016 | rs1508595 | G | A | rs1508595 | 20543847 | 1.81E-26 | NA | NA | NA | 979 European ancestry cases; 4,947 European ancestry controls | European(5926) | ALL(5926) | EUR(5926) | ALL(5926) | Testicular germ cell cancer | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D013736 | Testicular Neoplasms | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, Non-U.S. Gov't | C | NA |
| 12 | 88986016 | rs1508595 | G | A | rs1508595 | 23666239 | 1.29E-10 | NA | 2.38 | [1.85-3.03] | 582 European ancestry male cases; 1,056 European ancestry male controls | European(1638) | ALL(1638) | EUR(1638) | ALL(1638) | Testicular germ cell tumor | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D009373 | Neoplasms, Germ Cell and Embryonal | EFOID:0005088 | testicular carcinoma | Testicular tumor | rs1508595-T | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 12 | 88986016 | rs1508595 | G | A | rs1508595 | 23666240 | 4.91E-46 | NA | 2.44 | [2.07-2.88] | 986 European ancestry cases; 4,946 European ancestry controls | European(5932) | ALL(5932) | EUR(5932) | ALL(5932) | Testicular germ cell tumor | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D009373 | Neoplasms, Germ Cell and Embryonal | EFOID:0005088 | testicular carcinoma | Testicular tumor | rs1508595-G | Meta-Analysis | Research Support, Non-U.S. Gov't | C |
| 16 | 50028105 | rs7204293 | G | A | rs7204293 | 23666239 | 1.42E-05 | NA | 1.28 | [1.15-1.45] | 582 European ancestry male cases; 1,056 European ancestry male controls | European(1638) | ALL(1638) | EUR(1638) | ALL(1638) | Testicular germ cell tumor | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D009373 | Neoplasms, Germ Cell and Embryonal | EFOID:0005088 | testicular carcinoma | Testicular tumor | rs7204293- | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 16 | 50142944 | rs8046148 | A | G | rs8046148 | 23666239 | 3.00E-06 | NA | 1.2 | [1.11-1.30] | 582 European ancestry male cases; 1,056 European ancestry male controls | European(1638) | ALL(1638) | EUR(1638) | ALL(1638) | Testicular germ cell tumor | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D009373 | Neoplasms, Germ Cell and Embryonal | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 16 | 50142944 | rs8046148 | A | G | rs8046148 | 23666240 | 4.00E-09 | NA | 1.32 | [1.17-1.48] | 986 European ancestry cases; 4,946 European ancestry controls | European(5932) | ALL(5932) | EUR(5932) | ALL(5932) | Testicular germ cell tumor | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D009373 | Neoplasms, Germ Cell and Embryonal | EFOID:0005088 | testicular carcinoma | Testicular tumor | rs8046148-G | Meta-Analysis | Research Support, Non-U.S. Gov't | G |
| 16 | 74670458 | rs4888262 | C | T | rs4888262 | 23666239 | 5.00E-12 | NA | 1.26 | [1.18-1.34] | 582 European ancestry male cases; 1,056 European ancestry male controls | European(1638) | ALL(1638) | EUR(1638) | ALL(1638) | Testicular germ cell tumor | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D009373 | Neoplasms, Germ Cell and Embryonal | EFOID:0005088 | testicular carcinoma | Testicular tumor | rs4888262-C | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 17 | 56632543 | rs9905704 | G | T | rs9905704 | 23666239 | 4.00E-13 | NA | 1.27 | [1.18-1.33] | 582 European ancestry male cases; 1,056 European ancestry male controls | European(1638) | ALL(1638) | EUR(1638) | ALL(1638) | Testicular germ cell tumor | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D009373 | Neoplasms, Germ Cell and Embryonal | EFOID:0005088 | testicular carcinoma | Testicular tumor | rs9905704-T | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 17 | 56632543 | rs9905704 | G | T | rs9905704 | 23666240 | 3.00E-09 | NA | 1.21 | [1.10-1.34] | 986 European ancestry cases; 4,946 European ancestry controls | European(5932) | ALL(5932) | EUR(5932) | ALL(5932) | Testicular germ cell tumor | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D009373 | Neoplasms, Germ Cell and Embryonal | EFOID:0005088 | testicular carcinoma | Testicular tumor | rs9905704-T | Meta-Analysis | Research Support, Non-U.S. Gov't | T |
| 17 | 56656624 | rs1267543 | A | G | rs1267543 | 23666239 | 5.05E-07 | NA | 1.22 | [1.12-1.31] | 582 European ancestry male cases; 1,056 European ancestry male controls | European(1638) | ALL(1638) | EUR(1638) | ALL(1638) | Testicular germ cell tumor | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D009373 | Neoplasms, Germ Cell and Embryonal | EFOID:0005088 | testicular carcinoma | Testicular tumor | rs1267543- | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 17 | 57008128 | rs7221274 | A | G | rs7221274 | 23666239 | 4.04E-09 | NA | 1.2 | [1.12-1.28] | 582 European ancestry male cases; 1,056 European ancestry male controls | European(1638) | ALL(1638) | EUR(1638) | ALL(1638) | Testicular germ cell tumor | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D009373 | Neoplasms, Germ Cell and Embryonal | EFOID:0005088 | testicular carcinoma | Testicular tumor | rs7221274-A | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 18 | 47109693 | rs9951026 | G | A | rs9951026 | 23666239 | 5.00E-06 | NA | 1.22 | [1.12-1.33] | 582 European ancestry male cases; 1,056 European ancestry male controls | European(1638) | ALL(1638) | EUR(1638) | ALL(1638) | Testicular germ cell tumor | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D009373 | Neoplasms, Germ Cell and Embryonal | EFOID:0005088 | testicular carcinoma | Testicular tumor | NA | Research Support, N.I.H., Extramural | Meta-Analysis | Research Support, Non-U.S. Gov't |
| 21 | 47690068 | rs2839186 | C | T | rs2839186 | 23666240 | 1.00E-09 | NA | 1.26 | [1.15-1.38] | 986 European ancestry cases; 4,946 European ancestry controls | European(5932) | ALL(5932) | EUR(5932) | ALL(5932) | Testicular germ cell tumor | HPOID:0100617 | Testicular seminoma | DOID:5557 | testicular germ cell cancer | D009373 | Neoplasms, Germ Cell and Embryonal | EFOID:0005088 | testicular carcinoma | Testicular tumor | rs2839186-T | Meta-Analysis | Research Support, Non-U.S. Gov't | T |
Mapped by lexical matching(Total Items:0) |
|---|
| (Waiting for update.) |
Mapped by homologous gene(Total Items:0) |
|---|
| (Waiting for update.) |
| Disease ID | 863 |
|---|---|
| Disease | testicular seminoma |
| Case | (Waiting for update.) |