eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| smallpox | ||||
| Disease ID | 586 |
|---|---|
| Disease | smallpox |
| Definition | An acute, highly contagious, often fatal infectious disease caused by an orthopoxvirus characterized by a biphasic febrile course and distinctive progressive skin eruptions. Vaccination has succeeded in eradicating smallpox worldwide. (Dorland, 28th ed) |
| Synonym | classical smallpox ordinary smallpox smallpox (disorder) smallpox [disease/finding] smallpox disease smallpox nos smallpox nos (disorder) smallpox, nos smallpox, unspecified variola variola major variola, nos variolas |
| DOID | |
| ICD10 | |
| UMLS | C0037354 |
| MeSH | |
| SNOMED-CT | |
| Comorbidity | UMLS | Disease | Sentences' Count(Total Sentences:15) C0042214 | vaccinia | 8 C0037354 | variola | 2 C0037354 | smallpox | 2 C0011603 | dermatitis | 2 C0010232 | cowpox | 2 C0042769 | virus infection | 1 C0032914 | toxemia | 1 C0027059 | myocarditis | 1 C0085110 | severe combined immunodefic | 1 C0011615 | atopic dermatitis | 1 C0006285 | bronchopneumonia | 1 C0008049 | varicella | 1 C0009763 | conjunctivitis | 1 C0041296 | tuberculosis | 1 C0006142 | breast cancer | 1 |
| Curated Gene | (Waiting for update.) |
| Inferring Gene | (Waiting for update.) |
| Text Mined Gene | Entrez_id | Symbol | Score | Resource(Total Genes:86) 55811 | ADCY10 | 1.716 | DISEASES 146 | ADRA1D | 1.89 | DISEASES 23141 | ANKLE2 | 3.028 | DISEASES 8945 | BTRC | 1.323 | DISEASES 721 | C4B | 3.065 | DISEASES 820 | CAMP | 1.486 | DISEASES 4076 | CAPRIN1 | 3.566 | DISEASES 6364 | CCL20 | 1.511 | DISEASES 388372 | CCL4L1 | 1.457 | DISEASES 9560 | CCL4L2 | 1.312 | DISEASES 912 | CD1D | 1.505 | DISEASES 959 | CD40LG | 2.764 | DISEASES 79827 | CLMP | 4.258 | DISEASES 1369 | CPN1 | 1.298 | DISEASES 64478 | CSMD1 | 1.87 | DISEASES 8454 | CUL1 | 1.356 | DISEASES 4283 | CXCL9 | 1.796 | DISEASES 1727 | CYB5R3 | 3.553 | DISEASES 27071 | DAPP1 | 3.099 | DISEASES 51428 | DDX41 | 1.359 | DISEASES 9191 | DEDD | 1.741 | DISEASES 1755 | DMBT1 | 1.455 | DISEASES 1805 | DPT | 3.59 | DISEASES 10938 | EHD1 | 1.331 | DISEASES 1981 | EIF4G1 | 1.394 | DISEASES 30816 | ERVW-1 | 2.126 | DISEASES 2312 | FLG | 1.404 | DISEASES 2323 | FLT3LG | 2.177 | DISEASES 10146 | G3BP1 | 1.814 | DISEASES 57512 | GPR158 | 3.369 | DISEASES 2987 | GUK1 | 2.262 | DISEASES 3106 | HLA-B | 1.301 | DISEASES 3161 | HMMR | 1.321 | DISEASES 84525 | HOPX | 1.761 | DISEASES 3447 | IFNA13 | 2.683 | DISEASES 3456 | IFNB1 | 1.343 | DISEASES 3586 | IL10 | 1.133 | DISEASES 3663 | IRF5 | 1.02 | DISEASES 3665 | IRF7 | 2.999 | DISEASES 9445 | ITM2B | 1.173 | DISEASES 11275 | KLHL2 | 3.544 | DISEASES 3821 | KLRC1 | 1.294 | DISEASES 3823 | KLRC3 | 3.086 | DISEASES 3824 | KLRD1 | 2.068 | DISEASES 3916 | LAMP1 | 1.598 | DISEASES 3965 | LGALS9 | 1.346 | DISEASES 3980 | LIG3 | 1.99 | DISEASES 4050 | LTB | 1.808 | DISEASES 57506 | MAVS | 1.293 | DISEASES 8972 | MGAM | 1.29 | DISEASES 4285 | MIPEP | 2.653 | DISEASES 10108 | MKRN3-AS1 | 4.148 | DISEASES 283078 | MKX | 3.095 | DISEASES 2315 | MLANA | 1.224 | DISEASES 4599 | MX1 | 1.411 | DISEASES 4600 | MX2 | 1.482 | DISEASES 4615 | MYD88 | 1.046 | DISEASES 58484 | NLRC4 | 1.22 | DISEASES 65217 | PCDH15 | 1.608 | DISEASES 149830 | PRNT | 4.81 | DISEASES 149830 | PRNT | 4.598 | DISEASES 5625 | PRODH | 4.656 | DISEASES 5873 | RAB27A | 1.416 | DISEASES 9939 | RBM8A | 1.002 | DISEASES 25898 | RCHY1 | 1.89 | DISEASES 6231 | RPS26 | 2.232 | DISEASES 6256 | RXRA | 1.314 | DISEASES 404552 | SCGB1D4 | 1.436 | DISEASES 56907 | SPIRE1 | 3.228 | DISEASES 6772 | STAT1 | 1.469 | DISEASES 8831 | SYNGAP1 | 1.727 | DISEASES 284486 | THEM5 | 1.833 | DISEASES 7099 | TLR4 | 1.872 | DISEASES 10333 | TLR6 | 1.253 | DISEASES 51284 | TLR7 | 1.325 | DISEASES 54106 | TLR9 | 1.667 | DISEASES 387521 | TMEM189 | 1.522 | DISEASES 7124 | TNF | 2.067 | DISEASES 8742 | TNFSF12 | 1.096 | DISEASES 51399 | TRAPPC4 | 3.237 | DISEASES 706 | TSPO | 1.635 | DISEASES 7322 | UBE2D2 | 2.092 | DISEASES 7335 | UBE2V1 | 2.586 | DISEASES 7409 | VAV1 | 1.209 | DISEASES 7415 | VCP | 1.634 | DISEASES 6293 | VPS52 | 2.48 | DISEASES |
| Locus | (Waiting for update.) |
| Disease ID | 586 |
|---|---|
| Disease | smallpox |
| Integrated Phenotype | (Waiting for update.) |
| Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:5) HP:0003002 | Breast carcinoma | 1 HP:0012819 | Myocarditis | 1 HP:0001047 | Atopic dermatitis | 1 HP:0001873 | Low platelet count | 1 HP:0000509 | Conjunctivitis | 1 |
| Disease ID | 586 |
|---|---|
| Disease | smallpox |
| Manually Symptom | UMLS | Name(Total Manually Symptoms:24) C1963137 | hydrocephalus C1611280 | allergy C0854532 | myopericarditis C0374992 | mycoplasma C0275522 | subclinical infection C0275522 | inapparent infection C0264523 | pulmonary calcification C0262984 | spongiotic dermatitis C0205721 | nosocomial infection C0042749 | viraemia C0042740 | viral syndrome C0042216 | vaccinia C0039128 | syphilis C0037285 | skin manifestations C0037284 | skin lesions C0034152 | anaphylactoid purpura C0025202 | malignant melanomas C0025010 | measles C0019087 | hemorrhagic diathesis C0015230 | rash C0014038 | encephalitis C0007117 | basal cell epithelioma C0007114 | skin cancer C0003864 | arthritis |
| Text Mined Symptom | UMLS | Name | Sentences' Count(Total Symptoms:1) |
Manually Genotype(Total Text Mining Genotypes:0) |
|---|
| (Waiting for update.) |
Text Mining Genotype(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
All Snps(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Annotation(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:168) | |||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CHR | POS | SNPID | REF | ALT | ORI_SNPID | PMID | P_VALUE | P_VALUE_TEXT | OR/BETA | CI95_TEXT | GWAS_INITIAL_SAMPLE_SIZE | SUB_POPULATION | SUPER_POPULATION | GWAS_TRAIT | HPO_ID | HPO_TERM | DO_ID | DO_TERM | MESH_ID | MESH_TERM | EFO_ID | EFO_TERM | DOLITE_TERM | RISK_ALLELE | PUBLICATION_TYPE | AA | GENE_SYMBOL | TYPE | REFGENE |
| 1 | 20518226 | rs3179690 | G | A | rs3179690 | 22661280 | 3.11E-08 | NA | NA | NA | 537 European ancestry individuals; 207 African American individuals | African American(207) | European(537) | ALL(744) | AFR(207) | EUR(537) | ALL(744) | Secreted IFN-gamma response to smallpox vaccine | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | NA | NA | NA | NA | Virus disease | NA | Research Support, N.I.H., Extramural |
| 1 | 22373624 | rs2501276 | C | T | rs2501276 | 22610502 | 2.00E-07 | NA | NA | NA | Up to 512 European ancestry individuals; 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune response to smallpox vaccine (IL-6) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease | rs2501276-A | Research Support, N.I.H., Extramural |
| 1 | 58367236 | rs6679454 | A | G | rs6679454 | 22610502 | 3.00E-07 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IL-10) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004645 | cytokine measurement | Virus disease | rs6679454-G | Research Support, N.I.H., Extramural |
| 1 | 69894849 | rs11209457 | G | A | rs11209457 | 22661280 | 0.000000485 | NA | NA | NA | 537 European ancestry individuals; 207 African American individuals | African American(207) | European(537) | ALL(744) | AFR(207) | EUR(537) | ALL(744) | Secreted IFN-gamma response to smallpox vaccine | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | NA | NA | NA | NA | Virus disease | NA | Research Support, N.I.H., Extramural |
| 1 | 111033809 | rs4839431 | T | C | rs4839431 | 22610502 | 2.00E-07 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IFN-alpha) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease | rs4839431-A | Research Support, N.I.H., Extramural |
| 1 | 112392360 | rs12044963 | G | T | rs12044963 | 22610502 | 9.00E-10 | AA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IFN-alpha) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease | rs12044963-A | Research Support, N.I.H., Extramural |
| 1 | 178142208 | rs316274 | G | A | rs316274 | 22542470 | 8.00E-07 | NA | NA | NA | 217 African American ancestry individuals; 580 European ancestry individuals; 217 Hispanic ancestry individuals | European(580) | African American(217) | Hispanic(217) | ALL(1014) | HIS(217) | AFR(217) | EUR(580) | ALL(1014) | Immune response to smallpox vaccine (IL-6) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease |
| 1 | 189589339 | rs10489759 | C | T | rs10489759 | 22542470 | 8.00E-08 | NA | NA | NA | 217 African American ancestry individuals; 580 European ancestry individuals; 217 Hispanic ancestry individuals | European(580) | African American(217) | Hispanic(217) | ALL(1014) | HIS(217) | AFR(217) | EUR(580) | ALL(1014) | Immune response to smallpox vaccine (IL-6) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease |
| 1 | 235092600 | rs908327 | A | C | rs908327 | 22610502 | 5.00E-10 | AA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IL-2) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004645 | cytokine measurement | Virus disease | rs908327-C | Research Support, N.I.H., Extramural |
| 1 | 240706107 | rs10495471 | A | G | rs10495471 | 22542470 | 2.00E-07 | NA | NA | NA | 217 African American ancestry individuals; 580 European ancestry individuals; 217 Hispanic ancestry individuals | European(580) | African American(217) | Hispanic(217) | ALL(1014) | HIS(217) | AFR(217) | EUR(580) | ALL(1014) | Immune response to smallpox vaccine (IL-6) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease |
| 2 | 26272602 | rs13388915 | G | A | rs13388915 | 22542470 | 8.00E-06 | NA | NA | NA | 217 African American ancestry individuals; 580 European ancestry individuals; 217 Hispanic ancestry individuals | European(580) | African American(217) | Hispanic(217) | ALL(1014) | HIS(217) | AFR(217) | EUR(580) | ALL(1014) | Immune response to smallpox vaccine (IL-6) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease |
| 2 | 33121504 | rs6728021 | A | G | rs6728021 | 22610502 | 4.00E-08 | NA | NA | NA | Up to 512 European ancestry individuals; 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune response to smallpox vaccine (IL-6) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease | rs6728021-G | Research Support, N.I.H., Extramural |
| 2 | 33301947 | rs542631 | T | G | rs542631 | 22610502 | 1.00E-07 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IFN-alpha) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease | rs542631-A | Research Support, N.I.H., Extramural |
| 2 | 44662475 | rs13414205 | C | T | rs13414205 | 22610502 | 7.00E-08 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted TNF-alpha) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004645 | cytokine measurement | Virus disease | rs13414205-A | Research Support, N.I.H., Extramural |
| 2 | 68359897 | rs4078978 | C | T | rs4078978 | 22610502 | 2.00E-18 | AA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IFN-alpha) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease | rs4078978-A | Research Support, N.I.H., Extramural |
| 2 | 74463566 | rs13006863 | C | T | rs13006863 | 22610502 | 5.00E-07 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted TNF-alpha) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004645 | cytokine measurement | Virus disease | rs13006863-A | Research Support, N.I.H., Extramural |
| 2 | 85524369 | rs6737773 | A | G | rs6737773 | 22661280 | 4.27E-08 | NA | NA | NA | 537 European ancestry individuals; 207 African American individuals | African American(207) | European(537) | ALL(744) | AFR(207) | EUR(537) | ALL(744) | CD8+ T cell IFN-gamma response to smallpox vaccine | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | NA | NA | NA | NA | Virus disease | NA | Research Support, N.I.H., Extramural |
| 2 | 123225623 | rs17007761 | C | A | rs17007761 | 22610502 | 1.00E-08 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IFN-alpha) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease | rs17007761-A | Research Support, N.I.H., Extramural |
| 2 | 150147278 | rs10432496 | C | T | rs10432496 | 22610502 | 6.00E-08 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IL-2) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004645 | cytokine measurement | Virus disease | rs10432496-A | Research Support, N.I.H., Extramural |
| 2 | 151725792 | rs10195263 | G | A | rs10195263 | 22610502 | 3.00E-08 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IFN-alpha) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease | rs10195263-G | Research Support, N.I.H., Extramural |
| 2 | 177511440 | rs16864122 | C | T | rs16864122 | 22661280 | 0.000000252 | NA | NA | NA | 537 European ancestry individuals; 207 African American individuals | African American(207) | European(537) | ALL(744) | AFR(207) | EUR(537) | ALL(744) | CD8+ T cell IFN-gamma response to smallpox vaccine | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | NA | NA | NA | NA | Virus disease | NA | Research Support, N.I.H., Extramural |
| 2 | 219840891 | rs359965 | G | A | rs359965 | 22542470 | 2.00E-06 | NA | NA | NA | 217 African American ancestry individuals; 580 European ancestry individuals; 217 Hispanic ancestry individuals | European(580) | African American(217) | Hispanic(217) | ALL(1014) | HIS(217) | AFR(217) | EUR(580) | ALL(1014) | Immune response to smallpox vaccine (IL-6) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease |
| 2 | 227915924 | rs2272205 | T | C | rs2272205 | 22610502 | 3.00E-09 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IFN-alpha) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease | rs2272205-G | Research Support, N.I.H., Extramural |
| 2 | 228481419 | rs11889798 | C | T | rs11889798 | 22610502 | 4.00E-07 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted TNF-alpha) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004645 | cytokine measurement | Virus disease | rs11889798-A | Research Support, N.I.H., Extramural |
| 2 | 232624863 | rs4973479 | C | T | rs4973479 | 22661280 | 0.000000315 | NA | NA | NA | 537 European ancestry individuals; 207 African American individuals | African American(207) | European(537) | ALL(744) | AFR(207) | EUR(537) | ALL(744) | Total IFN-gamma response to smallpox vaccine | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | NA | NA | NA | NA | Virus disease | NA | Research Support, N.I.H., Extramural |
| 3 | 3130645 | rs3804795 | T | C | rs3804795 | 22542470 | 1.00E-06 | NA | NA | NA | 217 African American ancestry individuals; 580 European ancestry individuals; 217 Hispanic ancestry individuals | European(580) | African American(217) | Hispanic(217) | ALL(1014) | HIS(217) | AFR(217) | EUR(580) | ALL(1014) | Immune response to smallpox vaccine (IL-6) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease |
| 3 | 3375784 | rs9835812 | G | T | rs9835812 | 22542470 | 8.00E-07 | NA | NA | NA | 217 African American ancestry individuals; 580 European ancestry individuals; 217 Hispanic ancestry individuals | European(580) | African American(217) | Hispanic(217) | ALL(1014) | HIS(217) | AFR(217) | EUR(580) | ALL(1014) | Immune response to smallpox vaccine (IL-6) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease |
| 3 | 45817418 | rs758386 | A | G | rs758386 | 22610502 | 2.00E-07 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted TNF-alpha) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004645 | cytokine measurement | Virus disease | rs758386-A | Research Support, N.I.H., Extramural |
| 3 | 52844534 | rs17331151 | C | T | rs17331151 | 22610502 | 2.00E-09 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IL-2) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004645 | cytokine measurement | Virus disease | rs17331151-A | Research Support, N.I.H., Extramural |
| 3 | 52913279 | rs3796352 | C | T | rs3796352 | 22610502 | 5.00E-07 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IL-2) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004645 | cytokine measurement | Virus disease | rs3796352-A | Research Support, N.I.H., Extramural |
| 3 | 53147576 | rs13088281 | C | A | rs13088281 | 22610502 | 3.00E-11 | AA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IL-2) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004645 | cytokine measurement | Virus disease | rs13088281-A | Research Support, N.I.H., Extramural |
| 3 | 55035874 | rs4955826 | C | T | rs4955826 | 22542470 | 5.00E-06 | NA | NA | NA | 217 African American ancestry individuals; 580 European ancestry individuals; 217 Hispanic ancestry individuals | European(580) | African American(217) | Hispanic(217) | ALL(1014) | HIS(217) | AFR(217) | EUR(580) | ALL(1014) | Immune response to smallpox vaccine (IL-6) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease |
| 3 | 133589324 | rs9835973 | C | T | rs9835973 | 22610502 | 7.00E-08 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IL-1beta) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004645 | cytokine measurement | Virus disease | rs9835973-A | Research Support, N.I.H., Extramural |
| 3 | 152535365 | rs10513432 | T | C | rs10513432 | 22610502 | 4.00E-07 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IL-2) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004645 | cytokine measurement | Virus disease | rs10513432-G | Research Support, N.I.H., Extramural |
| 3 | 153184656 | rs6778194 | A | C | rs6778194 | 22610502 | 2.00E-09 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IFN-alpha) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease | rs6778194-C | Research Support, N.I.H., Extramural |
| 3 | 169080185 | rs9883650 | T | G | rs9883650 | 22610502 | 4.00E-07 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IL-1beta) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004645 | cytokine measurement | Virus disease | rs9883650-C | Research Support, N.I.H., Extramural |
| 3 | 188584679 | rs13067593 | A | G | rs13067593 | 22610502 | 8.00E-08 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IFN-alpha) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease | rs13067593-G | Research Support, N.I.H., Extramural |
| 3 | 191521852 | rs1516489 | A | C | rs1516489 | 22610502 | 8.00E-08 | NA | NA | NA | Up to 512 European ancestry individuals; 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune response to smallpox vaccine (IL-6) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease | rs1516489-C | Research Support, N.I.H., Extramural |
| 4 | 282499 | rs11723261 | A | G | rs11723261 | 22542470 | 4.00E-06 | NA | NA | NA | 217 African American ancestry individuals; 580 European ancestry individuals; 217 Hispanic ancestry individuals | European(580) | African American(217) | Hispanic(217) | ALL(1014) | HIS(217) | AFR(217) | EUR(580) | ALL(1014) | Immune response to smallpox vaccine (IL-6) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease |
| 4 | 16940391 | rs16894201 | G | T | rs16894201 | 22661280 | 0.000000145 | NA | NA | NA | 537 European ancestry individuals; 207 African American individuals | African American(207) | European(537) | ALL(744) | AFR(207) | EUR(537) | ALL(744) | CD8+ T cell IFN-gamma response to smallpox vaccine | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | NA | NA | NA | NA | Virus disease | NA | Research Support, N.I.H., Extramural |
| 4 | 28489837 | rs16880706 | T | C | rs16880706 | 22661280 | 0.000000354 | NA | NA | NA | 537 European ancestry individuals; 207 African American individuals | African American(207) | European(537) | ALL(744) | AFR(207) | EUR(537) | ALL(744) | CD8+ T cell IFN-gamma response to smallpox vaccine | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | NA | NA | NA | NA | Virus disease | NA | Research Support, N.I.H., Extramural |
| 4 | 42453253 | rs10517025 | C | T | rs10517025 | 22610502 | 2.00E-07 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IFN-alpha) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease | rs10517025-A | Research Support, N.I.H., Extramural |
| 4 | 75160824 | rs16850864 | C | T | rs16850864 | 22610502 | 7.00E-09 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IL-1beta) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004645 | cytokine measurement | Virus disease | rs16850864-A | Research Support, N.I.H., Extramural |
| 4 | 75170140 | rs16850885 | G | A | rs16850885 | 22610502 | 7.00E-09 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IL-1beta) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004645 | cytokine measurement | Virus disease | rs16850885-A | Research Support, N.I.H., Extramural |
| 4 | 77889994 | rs2645668 | T | C | rs2645668 | 22661280 | 7.25E-08 | NA | NA | NA | 537 European ancestry individuals; 207 African American individuals | African American(207) | European(537) | ALL(744) | AFR(207) | EUR(537) | ALL(744) | CD8+ T cell IFN-gamma response to smallpox vaccine | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | NA | NA | NA | NA | Virus disease | NA | Research Support, N.I.H., Extramural |
| 4 | 146853165 | rs2048161 | A | G | rs2048161 | 22610502 | 6.00E-12 | AA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IFN-alpha) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease | rs2048161-A | Research Support, N.I.H., Extramural |
| 4 | 148884189 | rs7658486 | C | T | rs7658486 | 22610502 | 1.00E-08 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IL-12p40) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease | rs7658486-A | Research Support, N.I.H., Extramural |
| 4 | 155316122 | rs902464 | T | C | rs902464 | 22610502 | 3.00E-07 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IL-1beta) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004645 | cytokine measurement | Virus disease | rs902464-A | Research Support, N.I.H., Extramural |
| 4 | 168264249 | rs13111850 | C | T | rs13111850 | 22610502 | 3.00E-11 | AA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IL-10) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004645 | cytokine measurement | Virus disease | rs13111850-G | Research Support, N.I.H., Extramural |
| 4 | 184305340 | rs1588571 | T | C | rs1588571 | 22661280 | 0.000000492 | NA | NA | NA | 537 European ancestry individuals; 207 African American individuals | African American(207) | European(537) | ALL(744) | AFR(207) | EUR(537) | ALL(744) | Secreted IFN-gamma response to smallpox vaccine | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | NA | NA | NA | NA | Virus disease | NA | Research Support, N.I.H., Extramural |
| 5 | 3558538 | rs10512697 | T | C | rs10512697 | 22542470 | 9.00E-07 | NA | NA | NA | 217 African American ancestry individuals; 580 European ancestry individuals; 217 Hispanic ancestry individuals | European(580) | African American(217) | Hispanic(217) | ALL(1014) | HIS(217) | AFR(217) | EUR(580) | ALL(1014) | Immune response to smallpox vaccine (IL-6) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease |
| 5 | 53902339 | rs2548621 | G | A | rs2548621 | 22542470 | 9.00E-07 | NA | NA | NA | 217 African American ancestry individuals; 580 European ancestry individuals; 217 Hispanic ancestry individuals | European(580) | African American(217) | Hispanic(217) | ALL(1014) | HIS(217) | AFR(217) | EUR(580) | ALL(1014) | Immune response to smallpox vaccine (IL-6) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease |
| 5 | 58560717 | rs17444059 | T | C | rs17444059 | 22610502 | 2.00E-08 | NA | NA | NA | Up to 512 European ancestry individuals; 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune response to smallpox vaccine (IL-6) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease | rs17444059-G | Research Support, N.I.H., Extramural |
| 5 | 86524315 | rs6890495 | G | A | rs6890495 | 22661280 | 1.39E-10 | NA | NA | NA | 537 European ancestry individuals; 207 African American individuals | African American(207) | European(537) | ALL(744) | AFR(207) | EUR(537) | ALL(744) | CD8+ T cell IFN-gamma response to smallpox vaccine | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | NA | NA | NA | NA | Virus disease | NA | Research Support, N.I.H., Extramural |
| 5 | 91518721 | rs10055544 | G | A | rs10055544 | 22610502 | 1.00E-07 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IL-10) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004645 | cytokine measurement | Virus disease | rs10055544-A | Research Support, N.I.H., Extramural |
| 5 | 119937691 | rs1584468 | G | A,C,T | rs1584468 | 22610502 | 9.00E-08 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IL-12p40) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease | rs1584468-A | Research Support, N.I.H., Extramural |
| 5 | 137599334 | rs11242417 | T | G | rs11242417 | 22610502 | 6.00E-08 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IL-12p40) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease | rs11242417-C | Research Support, N.I.H., Extramural |
| 5 | 138850905 | rs13181561 | G | A | rs13181561 | 22610502 | 3.00E-14 | EA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IFN-alpha) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease | rs13181561-G | Research Support, N.I.H., Extramural |
| 5 | 138949362 | rs261532 | G | T | rs261532 | 22610502 | 3.00E-07 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IFN-alpha) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease | rs261532-A | Research Support, N.I.H., Extramural |
| 5 | 167210472 | rs2973662 | A | G | rs2973662 | 22610502 | 5.00E-07 | NA | NA | NA | Up to 512 European ancestry individuals; 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune response to smallpox vaccine (IL-6) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease | rs2973662-A | Research Support, N.I.H., Extramural |
| 6 | 17241154 | rs1322846 | T | C | rs1322846 | 22542470 | 6.00E-07 | NA | NA | NA | 217 African American ancestry individuals; 580 European ancestry individuals; 217 Hispanic ancestry individuals | European(580) | African American(217) | Hispanic(217) | ALL(1014) | HIS(217) | AFR(217) | EUR(580) | ALL(1014) | Immune response to smallpox vaccine (IL-6) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease |
| 6 | 23437676 | rs7771911 | C | A | rs7771911 | 22610502 | 2.00E-12 | EA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IL-12p40) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease | rs7771911-A | Research Support, N.I.H., Extramural |
| 6 | 29434414 | rs4713226 | G | A | rs4713226 | 22610502 | 2.00E-08 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IFN-alpha) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease | rs4713226-A | Research Support, N.I.H., Extramural |
| 6 | 39528982 | rs9380880 | G | A | rs9380880 | 22542470 | 1.00E-07 | NA | NA | NA | 217 African American ancestry individuals; 580 European ancestry individuals; 217 Hispanic ancestry individuals | European(580) | African American(217) | Hispanic(217) | ALL(1014) | HIS(217) | AFR(217) | EUR(580) | ALL(1014) | Immune response to smallpox vaccine (IL-6) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease |
| 6 | 119866141 | rs1392089 | C | T | rs1392089 | 22610502 | 4.00E-07 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IL-2) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004645 | cytokine measurement | Virus disease | rs1392089-A | Research Support, N.I.H., Extramural |
| 6 | 128021803 | rs17299841 | A | C | rs17299841 | 22610502 | 2.00E-07 | NA | NA | NA | Up to 512 European ancestry individuals; 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune response to smallpox vaccine (IL-6) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease | rs17299841-C | Research Support, N.I.H., Extramural |
| 6 | 134576511 | rs9493873 | T | C | rs9493873 | 22610502 | 4.00E-07 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IFN-alpha) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease | rs9493873-G | Research Support, N.I.H., Extramural |
| 6 | 136001003 | rs9389316 | C | A | rs9389316 | 22610502 | 7.00E-13 | EA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IL-2) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004645 | cytokine measurement | Virus disease | rs9389316-A | Research Support, N.I.H., Extramural |
| 6 | 145287366 | rs1953793 | A | G | rs1953793 | 22661280 | 0.000000263 | NA | NA | NA | 537 European ancestry individuals; 207 African American individuals | African American(207) | European(537) | ALL(744) | AFR(207) | EUR(537) | ALL(744) | CD8+ T cell IFN-gamma response to smallpox vaccine | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | NA | NA | NA | NA | Virus disease | NA | Research Support, N.I.H., Extramural |
| 6 | 145367318 | rs6570670 | T | G | rs6570670 | 22661280 | 4.74E-08 | NA | NA | NA | 537 European ancestry individuals; 207 African American individuals | African American(207) | European(537) | ALL(744) | AFR(207) | EUR(537) | ALL(744) | CD8+ T cell IFN-gamma response to smallpox vaccine | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | NA | NA | NA | NA | Virus disease | NA | Research Support, N.I.H., Extramural |
| 6 | 154331184 | rs1319339 | T | C | rs1319339 | 22661280 | 0.000000491 | NA | NA | NA | 537 European ancestry individuals; 207 African American individuals | African American(207) | European(537) | ALL(744) | AFR(207) | EUR(537) | ALL(744) | Total IFN-gamma response to smallpox vaccine | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | NA | NA | NA | NA | Virus disease | NA | Research Support, N.I.H., Extramural |
| 6 | 168511016 | rs1473500 | C | T | rs1473500 | 22610502 | 3.00E-07 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IL-2) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004645 | cytokine measurement | Virus disease | rs1473500-A | Research Support, N.I.H., Extramural |
| 7 | 7571420 | rs17168526 | T | C | rs17168526 | 22610502 | 6.00E-08 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IL-1beta) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004645 | cytokine measurement | Virus disease | rs17168526-G | Research Support, N.I.H., Extramural |
| 7 | 27335561 | rs11564024 | T | G | rs11564024 | 22610502 | 3.00E-08 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IL-1beta) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004645 | cytokine measurement | Virus disease | rs11564024-C | Research Support, N.I.H., Extramural |
| 7 | 68050413 | rs1403155 | G | A | rs1403155 | 22610502 | 2.00E-08 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IL-2) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004645 | cytokine measurement | Virus disease | rs1403155-A | Research Support, N.I.H., Extramural |
| 7 | 72746648 | rs6943090 | C | T | rs6943090 | 22610502 | 3.00E-07 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IL-12p40) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease | rs6943090-A | Research Support, N.I.H., Extramural |
| 7 | 79796815 | rs2523194 | A | G | rs2523194 | 22661280 | 0.000000148 | NA | NA | NA | 537 European ancestry individuals; 207 African American individuals | African American(207) | European(537) | ALL(744) | AFR(207) | EUR(537) | ALL(744) | Total IFN-gamma response to smallpox vaccine | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | NA | NA | NA | NA | Virus disease | NA | Research Support, N.I.H., Extramural |
| 7 | 94047266 | rs3736638 | C | A | rs3736638 | 22610502 | 3.00E-07 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IL-12p40) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease | rs3736638-A | Research Support, N.I.H., Extramural |
| 7 | 95600368 | rs13231718 | T | G | rs13231718 | 22610502 | 5.00E-09 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IL-10) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004645 | cytokine measurement | Virus disease | rs13231718-C | Research Support, N.I.H., Extramural |
| 7 | 119606632 | rs17142462 | C | T | rs17142462 | 22610502 | 3.00E-09 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IL-12p40) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease | rs17142462-A | Research Support, N.I.H., Extramural |
| 7 | 134785741 | rs17231212 | T | C | rs17231212 | 22610502 | 2.00E-08 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IL-10) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004645 | cytokine measurement | Virus disease | rs17231212-G | Research Support, N.I.H., Extramural |
| 7 | 139576284 | rs17161201 | G | A | rs17161201 | 22661280 | 0.00000015 | NA | NA | NA | 537 European ancestry individuals; 207 African American individuals | African American(207) | European(537) | ALL(744) | AFR(207) | EUR(537) | ALL(744) | Total IFN-gamma response to smallpox vaccine | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | NA | NA | NA | NA | Virus disease | NA | Research Support, N.I.H., Extramural |
| 8 | 4299883 | rs17070309 | G | A | rs17070309 | 22542470 | 5.00E-07 | NA | NA | NA | 217 African American ancestry individuals; 580 European ancestry individuals; 217 Hispanic ancestry individuals | European(580) | African American(217) | Hispanic(217) | ALL(1014) | HIS(217) | AFR(217) | EUR(580) | ALL(1014) | Immune response to smallpox vaccine (IL-6) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease |
| 8 | 11409992 | rs2255327 | C | T | rs2255327 | 22610502 | 3.00E-07 | NA | NA | NA | Up to 512 European ancestry individuals; 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune response to smallpox vaccine (IL-6) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease | rs2255327-A | Research Support, N.I.H., Extramural |
| 8 | 18355897 | rs4921930 | C | T | rs4921930 | 22661280 | 1.15E-12 | NA | NA | NA | 537 European ancestry individuals; 207 African American individuals | African American(207) | European(537) | ALL(744) | AFR(207) | EUR(537) | ALL(744) | CD8+ T cell IFN-gamma response to smallpox vaccine | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | NA | NA | NA | NA | Virus disease | NA | Research Support, N.I.H., Extramural |
| 8 | 18360301 | rs1110820 | T | C | rs1110820 | 22661280 | 1.15E-12 | NA | NA | NA | 537 European ancestry individuals; 207 African American individuals | African American(207) | European(537) | ALL(744) | AFR(207) | EUR(537) | ALL(744) | CD8+ T cell IFN-gamma response to smallpox vaccine | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | NA | NA | NA | NA | Virus disease | NA | Research Support, N.I.H., Extramural |
| 8 | 33565378 | rs4469412 | G | A | rs4469412 | 22542470 | 9.00E-07 | NA | NA | NA | 217 African American ancestry individuals; 580 European ancestry individuals; 217 Hispanic ancestry individuals | European(580) | African American(217) | Hispanic(217) | ALL(1014) | HIS(217) | AFR(217) | EUR(580) | ALL(1014) | Immune response to smallpox vaccine (IL-6) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease |
| 8 | 33665680 | rs10503951 | A | G | rs10503951 | 22542470 | 3.00E-09 | NA | NA | NA | 217 African American ancestry individuals; 580 European ancestry individuals; 217 Hispanic ancestry individuals | European(580) | African American(217) | Hispanic(217) | ALL(1014) | HIS(217) | AFR(217) | EUR(580) | ALL(1014) | Immune response to smallpox vaccine (IL-6) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease |
| 8 | 33673011 | rs11786194 | A | G | rs11786194 | 22542470 | 9.00E-07 | NA | NA | NA | 217 African American ancestry individuals; 580 European ancestry individuals; 217 Hispanic ancestry individuals | European(580) | African American(217) | Hispanic(217) | ALL(1014) | HIS(217) | AFR(217) | EUR(580) | ALL(1014) | Immune response to smallpox vaccine (IL-6) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease |
| 8 | 33696302 | rs11787122 | A | G | rs11787122 | 22542470 | 8.54E-07 | NA | NA | NA | 217 African American ancestry individuals; 580 European ancestry individuals; 217 Hispanic ancestry individuals | European(580) | African American(217) | Hispanic(217) | ALL(1014) | HIS(217) | AFR(217) | EUR(580) | ALL(1014) | Immune response to smallpox vaccine (IL-6) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease |
| 8 | 56168059 | rs12542677 | C | T | rs12542677 | 22610502 | 2.00E-07 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IL-1beta) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004645 | cytokine measurement | Virus disease | rs12542677-A | Research Support, N.I.H., Extramural |
| 8 | 123973068 | rs10108684 | G | A | rs10108684 | 22542470 | 1.00E-08 | NA | NA | NA | 217 African American ancestry individuals; 580 European ancestry individuals; 217 Hispanic ancestry individuals | European(580) | African American(217) | Hispanic(217) | ALL(1014) | HIS(217) | AFR(217) | EUR(580) | ALL(1014) | Immune response to smallpox vaccine (IL-6) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease |
| 9 | 14119810 | rs7860845 | A | G | rs7860845 | 22661280 | 9.48E-14 | NA | NA | NA | 537 European ancestry individuals; 207 African American individuals | African American(207) | European(537) | ALL(744) | AFR(207) | EUR(537) | ALL(744) | Total IFN-gamma response to smallpox vaccine | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | NA | NA | NA | NA | Virus disease | NA | Research Support, N.I.H., Extramural |
| 9 | 32556380 | rs17290760 | A | G | rs17290760 | 22610502 | 1.00E-07 | NA | NA | NA | Up to 512 European ancestry individuals; 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune response to smallpox vaccine (IL-6) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease | rs17290760-G | Research Support, N.I.H., Extramural |
| 9 | 90209137 | rs3095748 | G | A | rs3095748 | 22610502 | 5.00E-07 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IFN-alpha) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease | rs3095748-G | Research Support, N.I.H., Extramural |
| 9 | 123914874 | rs9408926 | C | T | rs9408926 | 22610502 | 4.00E-08 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IFN-alpha) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease | rs9408926-A | Research Support, N.I.H., Extramural |
| 9 | 123951917 | rs9408928 | T | C | rs9408928 | 22610502 | 4.00E-09 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IFN-alpha) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease | rs9408928-G | Research Support, N.I.H., Extramural |
| 10 | 618685 | rs17221323 | T | C | rs17221323 | 22610502 | 1.00E-07 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IFN-alpha) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease | rs17221323-G | Research Support, N.I.H., Extramural |
| 10 | 6606541 | rs4748153 | C | T | rs4748153 | 22542470 | 3.00E-08 | NA | NA | NA | 217 African American ancestry individuals; 580 European ancestry individuals; 217 Hispanic ancestry individuals | European(580) | African American(217) | Hispanic(217) | ALL(1014) | HIS(217) | AFR(217) | EUR(580) | ALL(1014) | Immune response to smallpox vaccine (IL-6) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease |
| 10 | 9363877 | rs12247397 | A | G | rs12247397 | 22610502 | 3.00E-09 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IL-1beta) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004645 | cytokine measurement | Virus disease | rs12247397-G | Research Support, N.I.H., Extramural |
| 10 | 25918879 | rs12775535 | C | T | rs12775535 | 22542470 | 4.00E-09 | NA | NA | NA | 217 African American ancestry individuals; 580 European ancestry individuals; 217 Hispanic ancestry individuals | European(580) | African American(217) | Hispanic(217) | ALL(1014) | HIS(217) | AFR(217) | EUR(580) | ALL(1014) | Immune response to smallpox vaccine (IL-6) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease |
| 10 | 28025771 | rs10508727 | C | T | rs10508727 | 22542470 | 1.00E-10 | AA | NA | NA | 217 African American ancestry individuals; 580 European ancestry individuals; 217 Hispanic ancestry individuals | European(580) | African American(217) | Hispanic(217) | ALL(1014) | HIS(217) | AFR(217) | EUR(580) | ALL(1014) | Immune response to smallpox vaccine (IL-6) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease |
| 10 | 55384743 | rs12256830 | C | T | rs12256830 | 22542470 | 2.00E-10 | Hispanic | NA | NA | 217 African American ancestry individuals; 580 European ancestry individuals; 217 Hispanic ancestry individuals | European(580) | African American(217) | Hispanic(217) | ALL(1014) | HIS(217) | AFR(217) | EUR(580) | ALL(1014) | Immune response to smallpox vaccine (IL-6) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease |
| 10 | 70939801 | rs10998624 | G | A | rs10998624 | 22610502 | 1.00E-09 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IL-1beta) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004645 | cytokine measurement | Virus disease | rs10998624-A | Research Support, N.I.H., Extramural |
| 10 | 90746693 | rs983751 | A | C | rs983751 | 22661280 | 1.97E-08 | NA | NA | NA | 537 European ancestry individuals; 207 African American individuals | African American(207) | European(537) | ALL(744) | AFR(207) | EUR(537) | ALL(744) | Total IFN-gamma response to smallpox vaccine | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | NA | NA | NA | NA | Virus disease | NA | Research Support, N.I.H., Extramural |
| 10 | 90748736 | rs3758483 | C | T | rs3758483 | 22661280 | 1.97E-08 | NA | NA | NA | 537 European ancestry individuals; 207 African American individuals | African American(207) | European(537) | ALL(744) | AFR(207) | EUR(537) | ALL(744) | Total IFN-gamma response to smallpox vaccine | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | NA | NA | NA | NA | Virus disease | NA | Research Support, N.I.H., Extramural |
| 10 | 90756163 | rs9658691 | T | C | rs9658691 | 22661280 | 1.63E-09 | NA | NA | NA | 537 European ancestry individuals; 207 African American individuals | African American(207) | European(537) | ALL(744) | AFR(207) | EUR(537) | ALL(744) | Total IFN-gamma response to smallpox vaccine | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | NA | NA | NA | NA | Virus disease | NA | Research Support, N.I.H., Extramural |
| 10 | 96766934 | rs2860975 | A | C | rs2860975 | 22542470 | 2.00E-07 | NA | NA | NA | 217 African American ancestry individuals; 580 European ancestry individuals; 217 Hispanic ancestry individuals | European(580) | African American(217) | Hispanic(217) | ALL(1014) | HIS(217) | AFR(217) | EUR(580) | ALL(1014) | Immune response to smallpox vaccine (IL-6) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease |
| 10 | 96797470 | rs1934953 | C | T | rs1934953 | 22542470 | 5.00E-07 | NA | NA | NA | 217 African American ancestry individuals; 580 European ancestry individuals; 217 Hispanic ancestry individuals | European(580) | African American(217) | Hispanic(217) | ALL(1014) | HIS(217) | AFR(217) | EUR(580) | ALL(1014) | Immune response to smallpox vaccine (IL-6) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease |
| 10 | 100981547 | rs7094333 | C | T | rs7094333 | 22661280 | 1.04E-08 | NA | NA | NA | 537 European ancestry individuals; 207 African American individuals | African American(207) | European(537) | ALL(744) | AFR(207) | EUR(537) | ALL(744) | Secreted IFN-gamma response to smallpox vaccine | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | NA | NA | NA | NA | Virus disease | NA | Research Support, N.I.H., Extramural |
| 10 | 108500404 | rs10458732 | C | T | rs10458732 | 22661280 | 0.000000461 | NA | NA | NA | 537 European ancestry individuals; 207 African American individuals | African American(207) | European(537) | ALL(744) | AFR(207) | EUR(537) | ALL(744) | Secreted IFN-gamma response to smallpox vaccine | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | NA | NA | NA | NA | Virus disease | NA | Research Support, N.I.H., Extramural |
| 10 | 132847790 | rs12764951 | C | T | rs12764951 | 22661280 | 0.000000284 | NA | NA | NA | 537 European ancestry individuals; 207 African American individuals | African American(207) | European(537) | ALL(744) | AFR(207) | EUR(537) | ALL(744) | CD8+ T cell IFN-gamma response to smallpox vaccine | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | NA | NA | NA | NA | Virus disease | NA | Research Support, N.I.H., Extramural |
| 11 | 2764118 | rs2237875 | A | G | rs2237875 | 22661280 | 0.000000121 | NA | NA | NA | 537 European ancestry individuals; 207 African American individuals | African American(207) | European(537) | ALL(744) | AFR(207) | EUR(537) | ALL(744) | Total IFN-gamma response to smallpox vaccine | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | NA | NA | NA | NA | Virus disease | NA | Research Support, N.I.H., Extramural |
| 11 | 16358722 | rs1437635 | C | A | rs1437635 | 22661280 | 2.51E-08 | NA | NA | NA | 537 European ancestry individuals; 207 African American individuals | African American(207) | European(537) | ALL(744) | AFR(207) | EUR(537) | ALL(744) | Secreted IFN-gamma response to smallpox vaccine | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | NA | NA | NA | NA | Virus disease | NA | Research Support, N.I.H., Extramural |
| 11 | 38288593 | rs11034653 | C | T | rs11034653 | 22610502 | 2.00E-07 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IL-12p40) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease | rs11034653-A | Research Support, N.I.H., Extramural |
| 11 | 42315886 | rs7394570 | A | G | rs7394570 | 22542470 | 1.00E-06 | NA | NA | NA | 217 African American ancestry individuals; 580 European ancestry individuals; 217 Hispanic ancestry individuals | European(580) | African American(217) | Hispanic(217) | ALL(1014) | HIS(217) | AFR(217) | EUR(580) | ALL(1014) | Immune response to smallpox vaccine (IL-6) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease |
| 11 | 61494327 | rs4963243 | G | A | rs4963243 | 22610502 | 2.00E-07 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IL-2) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004645 | cytokine measurement | Virus disease | rs4963243-A | Research Support, N.I.H., Extramural |
| 11 | 70704905 | rs11237722 | C | T | rs11237722 | 22661280 | 0.000000121 | NA | NA | NA | 537 European ancestry individuals; 207 African American individuals | African American(207) | European(537) | ALL(744) | AFR(207) | EUR(537) | ALL(744) | Total IFN-gamma response to smallpox vaccine | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | NA | NA | NA | NA | Virus disease | NA | Research Support, N.I.H., Extramural |
| 11 | 100173537 | rs11223581 | A | G | rs11223581 | 22610502 | 9.00E-09 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IL-2) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004645 | cytokine measurement | Virus disease | rs11223581-G | Research Support, N.I.H., Extramural |
| 11 | 112064431 | rs7105056 | T | C | rs7105056 | 22610502 | 1.00E-08 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IL-12p40) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease | rs7105056-A | Research Support, N.I.H., Extramural |
| 11 | 118075152 | rs11216816 | C | A | rs11216816 | 22661280 | 0.00000045 | NA | NA | NA | 537 European ancestry individuals; 207 African American individuals | African American(207) | European(537) | ALL(744) | AFR(207) | EUR(537) | ALL(744) | Secreted IFN-gamma response to smallpox vaccine | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | NA | NA | NA | NA | Virus disease | NA | Research Support, N.I.H., Extramural |
| 11 | 123864216 | rs1453654 | T | C | rs1453654 | 22661280 | 0.000000141 | NA | NA | NA | 537 European ancestry individuals; 207 African American individuals | African American(207) | European(537) | ALL(744) | AFR(207) | EUR(537) | ALL(744) | Secreted IFN-gamma response to smallpox vaccine | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | NA | NA | NA | NA | Virus disease | NA | Research Support, N.I.H., Extramural |
| 12 | 13872044 | rs2268118 | G | T | rs2268118 | 22610502 | 1.00E-08 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IL-2) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004645 | cytokine measurement | Virus disease | rs2268118-A | Research Support, N.I.H., Extramural |
| 12 | 44153826 | rs4251424 | C | T | rs4251424 | 22610502 | 2.00E-08 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted TNF-alpha) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004645 | cytokine measurement | Virus disease | rs4251424-A | Research Support, N.I.H., Extramural |
| 12 | 56828056 | rs11171846 | C | T | rs11171846 | 22610502 | 6.00E-10 | AA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IFN-alpha) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease | rs11171846-A | Research Support, N.I.H., Extramural |
| 12 | 63249773 | rs3847906 | A | G | rs3847906 | 22661280 | 0.000000186 | NA | NA | NA | 537 European ancestry individuals; 207 African American individuals | African American(207) | European(537) | ALL(744) | AFR(207) | EUR(537) | ALL(744) | Secreted IFN-gamma response to smallpox vaccine | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | NA | NA | NA | NA | Virus disease | NA | Research Support, N.I.H., Extramural |
| 12 | 82984879 | rs12425131 | G | A | rs12425131 | 22542470 | 2.00E-06 | NA | NA | NA | 217 African American ancestry individuals; 580 European ancestry individuals; 217 Hispanic ancestry individuals | European(580) | African American(217) | Hispanic(217) | ALL(1014) | HIS(217) | AFR(217) | EUR(580) | ALL(1014) | Immune response to smallpox vaccine (IL-6) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease |
| 12 | 83019188 | rs11115322 | T | C | rs11115322 | 22542470 | 3.00E-06 | NA | NA | NA | 217 African American ancestry individuals; 580 European ancestry individuals; 217 Hispanic ancestry individuals | European(580) | African American(217) | Hispanic(217) | ALL(1014) | HIS(217) | AFR(217) | EUR(580) | ALL(1014) | Immune response to smallpox vaccine (IL-6) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease |
| 12 | 133345809 | rs12282 | C | T | rs12282 | 22542470 | 3.00E-07 | NA | NA | NA | 217 African American ancestry individuals; 580 European ancestry individuals; 217 Hispanic ancestry individuals | European(580) | African American(217) | Hispanic(217) | ALL(1014) | HIS(217) | AFR(217) | EUR(580) | ALL(1014) | Immune response to smallpox vaccine (IL-6) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease |
| 13 | 74995660 | rs17714988 | A | G | rs17714988 | 22610502 | 3.00E-07 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IFN-alpha) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease | rs17714988-G | Research Support, N.I.H., Extramural |
| 13 | 99385990 | rs9582259 | T | G | rs9582259 | 22610502 | 3.00E-08 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IL-1beta) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004645 | cytokine measurement | Virus disease | rs9582259-C | Research Support, N.I.H., Extramural |
| 13 | 105091080 | rs7987983 | G | A | rs7987983 | 22661280 | 0.000000187 | NA | NA | NA | 537 European ancestry individuals; 207 African American individuals | African American(207) | European(537) | ALL(744) | AFR(207) | EUR(537) | ALL(744) | Secreted IFN-gamma response to smallpox vaccine | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | NA | NA | NA | NA | Virus disease | NA | Research Support, N.I.H., Extramural |
| 13 | 105112042 | rs7337090 | G | A | rs7337090 | 22661280 | 0.000000701 | NA | NA | NA | 537 European ancestry individuals; 207 African American individuals | African American(207) | European(537) | ALL(744) | AFR(207) | EUR(537) | ALL(744) | Secreted IFN-gamma response to smallpox vaccine | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | NA | NA | NA | NA | Virus disease | NA | Research Support, N.I.H., Extramural |
| 13 | 106785265 | rs1372791 | T | C | rs1372791 | 22610502 | 4.00E-07 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IL-2) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004645 | cytokine measurement | Virus disease | rs1372791-A | Research Support, N.I.H., Extramural |
| 13 | 106941798 | rs16968401 | G | A | rs16968401 | 22661280 | 0.00000035 | NA | NA | NA | 537 European ancestry individuals; 207 African American individuals | African American(207) | European(537) | ALL(744) | AFR(207) | EUR(537) | ALL(744) | Secreted IFN-gamma response to smallpox vaccine | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | NA | NA | NA | NA | Virus disease | NA | Research Support, N.I.H., Extramural |
| 14 | 49463484 | rs11845208 | A | G | rs11845208 | 22610502 | 1.00E-07 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IL-2) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004645 | cytokine measurement | Virus disease | rs11845208-G | Research Support, N.I.H., Extramural |
| 14 | 54167472 | rs210359 | A | C | rs210359 | 22610502 | 8.00E-08 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IFN-alpha) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease | rs210359-A | Research Support, N.I.H., Extramural |
| 14 | 61308337 | rs6573333 | T | G | rs6573333 | 22610502 | 3.00E-10 | EA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IFN-alpha) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease | rs6573333-A | Research Support, N.I.H., Extramural |
| 14 | 72350212 | rs10138587 | C | T | rs10138587 | 22661280 | 3.18E-08 | NA | NA | NA | 537 European ancestry individuals; 207 African American individuals | African American(207) | European(537) | ALL(744) | AFR(207) | EUR(537) | ALL(744) | CD8+ T cell IFN-gamma response to smallpox vaccine | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | NA | NA | NA | NA | Virus disease | NA | Research Support, N.I.H., Extramural |
| 14 | 98463157 | rs7140601 | T | C | rs7140601 | 22542470 | 7.00E-07 | NA | NA | NA | 217 African American ancestry individuals; 580 European ancestry individuals; 217 Hispanic ancestry individuals | European(580) | African American(217) | Hispanic(217) | ALL(1014) | HIS(217) | AFR(217) | EUR(580) | ALL(1014) | Immune response to smallpox vaccine (IL-6) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease |
| 15 | 25894658 | rs6576443 | C | T | rs6576443 | 22610502 | 6.00E-09 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IFN-alpha) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease | rs6576443-A | Research Support, N.I.H., Extramural |
| 15 | 54868668 | rs2553218 | G | T | rs2553218 | 22542470 | 8.00E-07 | NA | NA | NA | 217 African American ancestry individuals; 580 European ancestry individuals; 217 Hispanic ancestry individuals | European(580) | African American(217) | Hispanic(217) | ALL(1014) | HIS(217) | AFR(217) | EUR(580) | ALL(1014) | Immune response to smallpox vaccine (IL-6) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease |
| 15 | 81001278 | rs12148329 | T | G | rs12148329 | 22542470 | 9.00E-07 | NA | NA | NA | 217 African American ancestry individuals; 580 European ancestry individuals; 217 Hispanic ancestry individuals | European(580) | African American(217) | Hispanic(217) | ALL(1014) | HIS(217) | AFR(217) | EUR(580) | ALL(1014) | Immune response to smallpox vaccine (IL-6) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease |
| 16 | 21113272 | rs16970881 | G | A | rs16970881 | 22610502 | 1.00E-07 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IL-10) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004645 | cytokine measurement | Virus disease | rs16970881-A | Research Support, N.I.H., Extramural |
| 17 | 15826021 | rs859267 | A | C | rs859267 | 22610502 | 3.00E-07 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IL-12p40) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease | rs859267-C | Research Support, N.I.H., Extramural |
| 17 | 47566312 | rs16948200 | G | A | rs16948200 | 22610502 | 2.00E-08 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IL-2) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004645 | cytokine measurement | Virus disease | rs16948200-A | Research Support, N.I.H., Extramural |
| 17 | 58966538 | rs7224438 | T | C | rs7224438 | 22610502 | 4.00E-07 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IL-2) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004645 | cytokine measurement | Virus disease | rs7224438-G | Research Support, N.I.H., Extramural |
| 18 | 12550747 | rs1940973 | T | C | rs1940973 | 22542470 | 8.00E-07 | NA | NA | NA | 217 African American ancestry individuals; 580 European ancestry individuals; 217 Hispanic ancestry individuals | European(580) | African American(217) | Hispanic(217) | ALL(1014) | HIS(217) | AFR(217) | EUR(580) | ALL(1014) | Immune response to smallpox vaccine (IL-6) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease |
| 18 | 12606463 | rs9959145 | G | T | rs9959145 | 22542470 | 3.00E-08 | NA | NA | NA | 217 African American ancestry individuals; 580 European ancestry individuals; 217 Hispanic ancestry individuals | European(580) | African American(217) | Hispanic(217) | ALL(1014) | HIS(217) | AFR(217) | EUR(580) | ALL(1014) | Immune response to smallpox vaccine (IL-6) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease |
| 18 | 48524161 | rs9807334 | G | A | rs9807334 | 22610502 | 2.00E-07 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IFN-alpha) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease | rs9807334-A | Research Support, N.I.H., Extramural |
| 18 | 48713040 | rs8096445 | C | T | rs8096445 | 22610502 | 9.00E-09 | NA | NA | NA | Up to 512 European ancestry individuals; 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune response to smallpox vaccine (IL-6) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease | rs8096445-A | Research Support, N.I.H., Extramural |
| 19 | 52455249 | rs1549932 | G | A | rs1549932 | 22661280 | 0.000000308 | NA | NA | NA | 537 European ancestry individuals; 207 African American individuals | African American(207) | European(537) | ALL(744) | AFR(207) | EUR(537) | ALL(744) | CD8+ T cell IFN-gamma response to smallpox vaccine | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | NA | NA | NA | NA | Virus disease | NA | Research Support, N.I.H., Extramural |
| 19 | 56451049 | rs2043599 | A | G | rs2043599 | 22610502 | 5.00E-07 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IFN-alpha) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease | rs2043599-G | Research Support, N.I.H., Extramural |
| 20 | 1995534 | rs6081597 | A | G | rs6081597 | 22542470 | 7.00E-07 | NA | NA | NA | 217 African American ancestry individuals; 580 European ancestry individuals; 217 Hispanic ancestry individuals | European(580) | African American(217) | Hispanic(217) | ALL(1014) | HIS(217) | AFR(217) | EUR(580) | ALL(1014) | Immune response to smallpox vaccine (IL-6) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease |
| 20 | 4225573 | rs6052456 | C | T | rs6052456 | 22661280 | 0.000000375 | NA | NA | NA | 537 European ancestry individuals; 207 African American individuals | African American(207) | European(537) | ALL(744) | AFR(207) | EUR(537) | ALL(744) | CD8+ T cell IFN-gamma response to smallpox vaccine | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | NA | NA | NA | NA | Virus disease | NA | Research Support, N.I.H., Extramural |
| 21 | 36238507 | rs2834655 | G | A | rs2834655 | 22542470 | 5.00E-07 | NA | NA | NA | 217 African American ancestry individuals; 580 European ancestry individuals; 217 Hispanic ancestry individuals | European(580) | African American(217) | Hispanic(217) | ALL(1014) | HIS(217) | AFR(217) | EUR(580) | ALL(1014) | Immune response to smallpox vaccine (IL-6) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease |
| 21 | 40314704 | rs2836770 | A | G | rs2836770 | 22542470 | 3.00E-06 | NA | NA | NA | 217 African American ancestry individuals; 580 European ancestry individuals; 217 Hispanic ancestry individuals | European(580) | African American(217) | Hispanic(217) | ALL(1014) | HIS(217) | AFR(217) | EUR(580) | ALL(1014) | Immune response to smallpox vaccine (IL-6) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease |
| 21 | 47165429 | rs8127571 | A | G | rs8127571 | 22610502 | 2.00E-07 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IFN-alpha) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease | rs8127571-A | Research Support, N.I.H., Extramural |
| 22 | 23644794 | rs9608102 | C | T | rs9608102 | 22542470 | 8.00E-06 | NA | NA | NA | 217 African American ancestry individuals; 580 European ancestry individuals; 217 Hispanic ancestry individuals | European(580) | African American(217) | Hispanic(217) | ALL(1014) | HIS(217) | AFR(217) | EUR(580) | ALL(1014) | Immune response to smallpox vaccine (IL-6) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease |
| 22 | 34889097 | rs738968 | T | G | rs738968 | 22610502 | 8.00E-08 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted TNF-alpha) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004645 | cytokine measurement | Virus disease | rs738968-C | Research Support, N.I.H., Extramural |
| 22 | 49812502 | rs17000918 | C | A | rs17000918 | 22610502 | 4.00E-09 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IL-1beta) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004645 | cytokine measurement | Virus disease | rs17000918-A | Research Support, N.I.H., Extramural |
| X | 22148051 | rs1540283 | C | T | rs1540283 | 22610502 | 9.00E-09 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IFN-alpha) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease | rs1540283-G | Research Support, N.I.H., Extramural |
| X | 23383444 | rs5925760 | G | A | rs5925760 | 22610502 | 1.00E-07 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IFN-alpha) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease | rs5925760-A | Research Support, N.I.H., Extramural |
| X | 97864354 | rs4827947 | T | C | rs4827947 | 22610502 | 3.00E-07 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IL-1beta) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004645 | cytokine measurement | Virus disease | rs4827947-A | Research Support, N.I.H., Extramural |
| X | 114879876 | rs10218219 | G | A | rs10218219 | 22661280 | 6.92E-08 | NA | NA | NA | 537 European ancestry individuals; 207 African American individuals | African American(207) | European(537) | ALL(744) | AFR(207) | EUR(537) | ALL(744) | CD8+ T cell IFN-gamma response to smallpox vaccine | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | NA | NA | NA | NA | Virus disease | NA | Research Support, N.I.H., Extramural |
| X | 124073662 | rs7060947 | A | G | rs7060947 | 22610502 | 1.00E-07 | NA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IFN-alpha) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease | rs7060947-G | Research Support, N.I.H., Extramural |
| X | 145748908 | rs381365 | T | G | rs381365 | 22610502 | 2.00E-12 | AA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IFN-alpha) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease | rs381365-A | Research Support, N.I.H., Extramural |
| X | 149635295 | rs17252936 | A | G | rs17252936 | 22610502 | 6.00E-10 | AA | NA | NA | Up to 512 European ancestry individuals; up to 199 African American individuals | African American(199) | European(512) | ALL(711) | AFR(199) | EUR(512) | ALL(711) | Immune reponse to smallpox (secreted IFN-alpha) | HPOID:0005368 | Abnormality of humoral immunity | DOID:8736 | smallpox | D012899 | Smallpox | EFOID:0004873 | response to vaccine | Virus disease | rs17252936-G | Research Support, N.I.H., Extramural |
Mapped by lexical matching(Total Items:0) |
|---|
| (Waiting for update.) |
Mapped by homologous gene(Total Items:0) |
|---|
| (Waiting for update.) |
| Disease ID | 586 |
|---|---|
| Disease | smallpox |
| Case | (Waiting for update.) |