eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| pyomyositis | ||||
| Disease ID | 487 |
|---|---|
| Disease | pyomyositis |
| Definition | A suppurative infection of muscle. |
| Synonym | myositis, tropical pyomyositis, tropical tropical myositis tropical pyomyositis tropical pyomyositis (disorder) tropical pyomyositis [dup] (disorder) |
| Orphanet | |
| DOID | |
| UMLS | C0041188 |
| MeSH | |
| SNOMED-CT | |
| Comorbidity | UMLS | Disease | Sentences' Count(Total Sentences:17) C0270629 | epidural abscess | 4 C0003864 | arthritis | 3 C0029443 | osteomyelitis | 3 C0003874 | septic arthritis | 2 C0409974 | lupus erythematosus | 2 C0009492 | compartment syndrome | 2 C0024141 | systemic lupus erythematosus | 2 C1704437 | respiratory distress syndrome | 1 C0476089 | endometrial ca | 1 C0035222 | acute respiratory distress syndrome | 1 C0040896 | trichinellosis | 1 C0037054 | sickle cell trait | 1 C0027121 | myositis | 1 C0011847 | diabetes | 1 C0034065 | pulmonary embolism | 1 C0011849 | diabetes mellitus | 1 C0476089 | endometrial cancer | 1 |
| Curated Gene | (Waiting for update.) |
| Inferring Gene | (Waiting for update.) |
| Text Mined Gene | Entrez_id | Symbol | Score | Resource(Total Genes:14) 1645 | AKR1C1 | 2.301 | DISEASES 996 | CDC27 | 3.618 | DISEASES 1378 | CR1 | 1.467 | DISEASES 2157 | F8 | 1.448 | DISEASES 2214 | FCGR3A | 1.209 | DISEASES 2875 | GPT | 2.997 | DISEASES 3329 | HSPD1 | 1.673 | DISEASES 4151 | MB | 1.337 | DISEASES 79104 | MEG8 | 2.523 | DISEASES 3164 | NR4A1 | 2.231 | DISEASES 83695 | RHNO1 | 1.801 | DISEASES 6164 | RPL34 | 2.451 | DISEASES 8801 | SUCLG2 | 2.804 | DISEASES 7137 | TNNI3 | 1.364 | DISEASES |
| Locus | (Waiting for update.) |
| Disease ID | 487 |
|---|---|
| Disease | pyomyositis |
| Integrated Phenotype | HPO | Name(Total Integrated Phenotypes:12) HP:0100616 | Testicular teratoma HP:0001974 | Leukocytosis HP:0003326 | Myalgia HP:0001645 | Sudden cardiac death HP:0100838 | Recurrent cutaneous abscess formation HP:0001482 | Subcutaneous nodule HP:0001824 | Weight loss HP:0001945 | Fever HP:0100806 | Sepsis HP:0002719 | Recurrent infections HP:0100614 | Myositis HP:0000083 | Renal insufficiency |
| Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:14) HP:0001369 | Arthritis | 3 HP:0002754 | Bone infection | 3 HP:0100806 | Sepsis | 2 HP:0003095 | Septic arthritis | 2 HP:0002725 | Systemic lupus erythematosus | 2 HP:0003326 | Muscle pain | 2 HP:0100614 | Muscle inflammation | 1 HP:0001880 | Eosinophilia | 1 HP:0000969 | Dropsy | 1 HP:0002955 | Granulomatosis | 1 HP:0000819 | Diabetes mellitus | 1 HP:0001945 | Fever | 1 HP:0002098 | Respiratory distress | 1 HP:0012531 | Pain | 1 |
| Disease ID | 487 |
|---|---|
| Disease | pyomyositis |
| Manually Symptom | UMLS | Name(Total Manually Symptoms:6) |
| Text Mined Symptom | UMLS | Name | Sentences' Count(Total Symptoms:1) |
Manually Genotype(Total Text Mining Genotypes:0) |
|---|
| (Waiting for update.) |
Text Mining Genotype(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
All Snps(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Annotation(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
Mapped by lexical matching(Total Items:3) | ||||
|---|---|---|---|---|
| HP ID | HP Name | MP ID | MP Name | Annotation |
| HP:0000083 | Renal insufficiency | MP:0003335 | exocrine pancreatic insufficiency | inadequate synthesis and/or secretion of digestive enzymes by the exocrine portion of the pancreas, usually due to loss of acinar tissue from idiopathic atrophy or acute or chronic inflammation, causing maldigestion and malabsorption of nutrients |
| HP:0001824 | Weight loss | MP:0005114 | premature hair loss | release of fur at an earlier than expected time |
| HP:0001645 | Sudden cardiac death | MP:0012557 | decreased calcium uptake by cardiac muscle | decreased directed movement of calcium ions into cardiac muscle; decreased or disrupted uptake may give rise to energetic deficit and oxidative stress. leading to cardiac disease |
Mapped by homologous gene(Total Items:11) | ||||
|---|---|---|---|---|
| HP ID | HP Name | MP ID | MP Name | Annotation |
| HP:0100614 | Myositis | MP:0011635 | abnormal mitochondrial crista morphology | Any of the inward folds of the mitochondrial inner membrane; crista number, extent, and shape differ in mitochondria from different tissues and organisms; crista appear to be devices for increasing the surface area of the mitochondrial inner membrane, whe |
| HP:0100806 | Sepsis | MP:0011708 | decreased fibroblast cell migration | reduced frequency of or less rapid fibroblast cell migration that is accomplished by extension and retraction of a fibroblast pseudopodium |
| HP:0001945 | Fever | MP:0020254 | decreased collagen level | decreased level of the main structural protein of the various connective tissues in animals |
| HP:0001824 | Weight loss | MP:0020220 | decreased tear production | decreased production of the amount of fluid produced in the eye |
| HP:0002719 | Recurrent infections | MP:0020234 | decreased basal metabolism | decrease in heat production of an organism at the lowest level of cell chemistry in an inactive, awake, and fasting state |
| HP:0100838 | Recurrent cutaneous abscess formation | MP:0020329 | decreased capillary density | reduction in the number of capillaries in a given cross-sectional area of a tissue |
| HP:0000083 | Renal insufficiency | MP:0020316 | decreased vascular endothelial cell proliferation | decrease in the expansion rate of any vascular endothelial cell population by cell division |
| HP:0001974 | Leukocytosis | MP:0020154 | impaired humoral immune response | impaired response of the immune system that mediates secreted antibodies produced in B cells |
| HP:0001645 | Sudden cardiac death | MP:0020329 | decreased capillary density | reduction in the number of capillaries in a given cross-sectional area of a tissue |
| HP:0001482 | Subcutaneous nodule | MP:0013542 | abnormal submandibular gland branching morphogenesis | |
| HP:0003326 | Myalgia | MP:0020309 | increased creatine kinase activity | increased ability of to catalyze the reaction: ATP + creatine = N-phosphocreatine + ADP + 2 H(+). |
| Disease ID | 487 |
|---|---|
| Disease | pyomyositis |
| Case | (Waiting for update.) |