eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| purpura fulminans | ||||
| Disease ID | 1207 |
|---|---|
| Disease | purpura fulminans |
| Definition | A severe, rapidly fatal reaction occurring most commonly in children following an infectious illness. It is characterized by large, rapidly spreading skin hemorrhages, fever, or shock. Purpura fulminans often accompanies or is triggered by DISSEMINATED INTRAVASCULAR COAGULATION. |
| Synonym | fulminans purpura fulminans, purpura purpura fulminans (disorder) purpura fulminans [disease/finding] purpura, fulminans |
| DOID | |
| UMLS | C0085650 |
| MeSH | |
| SNOMED-CT | |
| Comorbidity | UMLS | Disease | Sentences' Count(Total Sentences:19) C0012739 | disseminated intravascular coagulation | 3 C0242666 | protein s deficiency | 2 C0032285 | pneumoniae | 2 C0012739 | disseminated intravascular coagulation (dic) | 2 C0022661 | chronic renal failure | 1 C0008049 | varicella infection | 1 C0152966 | pneumococcal sepsis | 1 C0003864 | arthritis | 1 C0021400 | influenzae | 1 C0024790 | paroxysmal nocturnal haemoglobinuria | 1 C0600327 | toxic shock syndrome | 1 C0085278 | antiphospholipid antibody syndrome | 1 C0009782 | connective tissue disease | 1 C0008049 | varicella | 1 C0398623 | thrombophilia | 1 C0025306 | meningococcal sepsis | 1 C0035078 | renal failure | 1 C0026272 | mixed connective tissue disease | 1 C0041471 | typhus | 1 |
| Curated Gene | Entrez_id | Symbol | Resource(Total Genes:1) |
| Inferring Gene | (Waiting for update.) |
| Text Mined Gene | Entrez_id | Symbol | Score | Resource(Total Genes:18) 114899 | C1QTNF3 | 4.264 | DISEASES 716 | C1S | 1.59 | DISEASES 721 | C4B | 3.056 | DISEASES 959 | CD40LG | 1.094 | DISEASES 29952 | DPP7 | 2.394 | DISEASES 2152 | F3 | 3.144 | DISEASES 2524 | FUT2 | 1.481 | DISEASES 2592 | GALT | 2.009 | DISEASES 133396 | IL31RA | 1.629 | DISEASES 11012 | KLK11 | 2.152 | DISEASES 55788 | LMBRD1 | 2.564 | DISEASES 4524 | MTHFR | 1.088 | DISEASES 4700 | NDUFA6 | 1.769 | DISEASES 5627 | PROS1 | 3.236 | DISEASES 5265 | SERPINA1 | 1.038 | DISEASES 462 | SERPINC1 | 5.147 | DISEASES 5345 | SERPINF2 | 1.841 | DISEASES 7056 | THBD | 3.426 | DISEASES |
| Locus | (Waiting for update.) |
| Disease ID | 1207 |
|---|---|
| Disease | purpura fulminans |
| Integrated Phenotype | (Waiting for update.) |
| Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:12) HP:0100806 | Sepsis | 3 HP:0005521 | Disseminated intravascular coagulation | 3 HP:0003256 | Coagulopathy | 1 HP:0004818 | Paroxysmal nocturnal hemoglobinuria | 1 HP:0003613 | Antiphospholipid antibodies | 1 HP:0000083 | Renal insufficiency | 1 HP:0002045 | Abnormally low body temperature | 1 HP:0001369 | Arthritis | 1 HP:0011880 | Acute disseminated intravascular coagulation | 1 HP:0003774 | End-stage renal failure | 1 HP:0100758 | Gangrene | 1 HP:0100724 | Hypercoagulability | 1 |
| Disease ID | 1207 |
|---|---|
| Disease | purpura fulminans |
| Manually Symptom | UMLS | Name(Total Manually Symptoms:9) |
| Text Mined Symptom | UMLS | Name | Sentences' Count(Total Symptoms:1) |
Manually Genotype(Total Text Mining Genotypes:0) |
|---|
| (Waiting for update.) |
Text Mining Genotype(Total Genotypes:0) | |
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| (Waiting for update.) | |
All Snps(Total Genotypes:0) | |
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| (Waiting for update.) | |
GWASdb Annotation(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
Mapped by lexical matching(Total Items:0) |
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| (Waiting for update.) |
Mapped by homologous gene(Total Items:0) |
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| (Waiting for update.) |
| Disease ID | 1207 |
|---|---|
| Disease | purpura fulminans |
| Case | (Waiting for update.) |