pre-eclampsia |
Disease ID | 182 |
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Disease | pre-eclampsia |
Definition | A complication of PREGNANCY, characterized by a complex of symptoms including maternal HYPERTENSION and PROTEINURIA with or without pathological EDEMA. Symptoms may range between mild and severe. Pre-eclampsia usually occurs after the 20th week of gestation, but may develop before this time in the presence of trophoblastic disease. |
Synonym | 1, preeclampsia eclampsia 1s, preeclampsia eclampsia eclampsia 1, preeclampsia eclampsia 1s, preeclampsia edema proteinuria hypertension gestosis edema-proteinuria-hypertension gestosis eph - edema, proteinuria and hypertension of pregnancy eph - oedema, proteinuria and hypertension of pregnancy eph complex eph gestosis eph toxemia eph toxemias gestosis, edema-proteinuria-hypertension gestosis, eph gestosis, hypertension-edema-proteinuria gestosis, proteinuria-edema-hypertension hypertension edema proteinuria gestosis hypertension-edema-proteinuria gestosis hypertensive disorder of pregnancy maternal toxemia of pregnancies, toxemia of pregnancy, toxemia pe - pre-eclampsia pee pee1 pet - pre-eclamptic toxaemia pet - pre-eclamptic toxemia pre eclampsia pre-eclampsia (disorder) pre-eclampsia [disease/finding] pre-eclampsia nos pre-eclampsia nos (disorder) pre-eclampsia, nos pre-eclampsia, unspecified pre-eclamptic nos pre-eclamptic toxaemia pre-eclamptic toxemia pre-eclamptic toxemia, nos preeclampsia preeclampsia eclampsia 1 preeclampsia eclampsia 1s preeclampsia/eclampsia 1 preg1 pregn toxemias pregnancies, toxemia of pregnancy toxaemia pregnancy toxemia pregnancy toxemia/hypertension pregnancy toxemias pregnancy, toxemia of proteinuria edema hypertension gestosis proteinuria-edema-hypertension gestosis proteinuric hypertension of pregnancy proteinuric hypertension of pregnancy (disorder) toxaemia nos toxaemia of pregnancy toxaemia of pregnancy, nos toxaemia pregnancy toxemia toxemia (pre)eclampsia toxemia in pregnancy toxemia nos toxemia nos (disorder) toxemia of pregnancies toxemia of pregnancy toxemia of pregnancy (disorder) toxemia of pregnancy, nos toxemia pregnancy toxemia, eph toxemia, pregnancy toxemias, eph toxemias, pregnancy |
Orphanet | |
OMIM | |
DOID | |
UMLS | C0032914 |
MeSH | |
SNOMED-CT | |
Comorbidity | UMLS | Disease | Sentences' Count(Total Sentences:100) C0020538 | hypertension | 40 C0162739 | hellp syndrome | 15 C0033687 | proteinuria | 14 C0011847 | diabetes | 12 C0042373 | vascular disease | 8 C0007222 | cardiovascular disease | 8 C0020538 | hypertensive disorder | 6 C0042870 | vitamin d deficiency | 5 C0042870 | vitamin d defic | 5 C0085207 | gestational diabetes | 5 C0340274 | gestational hypertension | 5 C0028754 | obesity | 5 C0032051 | placental insufficiency | 4 C0011854 | type 1 diabetes | 4 C0022876 | preterm labor | 4 C0022658 | kidney disease | 4 C0022116 | ischemia | 3 C0878544 | cardiomyopathy | 3 C0013537 | eclampsia | 3 C0020676 | hypothyroidism | 3 C0040034 | thrombocytopenia | 3 C0740394 | hyperuricemia | 2 C0018799 | heart disease | 2 C0000786 | miscarriage | 2 C0022661 | chronic kidney disease | 2 C0040053 | thrombosis | 2 C0264832 | peripartum cardiomyopathy | 2 C0948265 | metabolic syndrome | 2 C0011570 | depression | 2 C0018801 | heart failure | 2 C0031099 | periodontitis | 2 C0034063 | pulmonary edema | 2 C0006142 | breast cancer | 2 C0020538 | hypertensive disease | 2 C0011849 | diabetes mellitus | 2 C0022658 | renal disease | 2 C0035309 | retinopathy | 2 C0398623 | hypercoagulable state | 2 C0004096 | asthma | 2 C0547030 | visual disturbance | 2 C0020538 | high blood pressure | 2 C0031090 | periodontal disease | 2 C0020598 | hypoglycemia | 1 C0085113 | neurofibromatosis | 1 C0014175 | endometriosis | 1 C0020538 | vascular hypertension | 1 C0038436 | post-traumatic stress disorder | 1 C0021053 | immune disease | 1 C0270612 | leukoencephalopathy | 1 C0017661 | iga nephropathy | 1 C0000832 | placental abruption | 1 C0011603 | dermatitis | 1 C0035078 | renal failure | 1 C0012739 | disseminated intravascular coagulation | 1 C0032914 | preeclampsia | 1 C0032460 | polycystic ovary | 1 C0085580 | essential hypertension | 1 C0022658 | nephropathy | 1 C0085207 | gestational diabetes mellitus | 1 C0007789 | cerebral palsy | 1 C0027947 | neutropenia | 1 C0020550 | hyperthyroidism | 1 C0520679 | obstructive sleep apnea | 1 C0037315 | sleep-disordered breathing | 1 C0000786 | spontaneous abortion | 1 C0002766 | analgesia | 1 C0037354 | smallpox | 1 C0031511 | pheochromocytoma | 1 C0035258 | restless legs | 1 C0085278 | antiphospholipid syndrome | 1 C0079924 | oligohydramnios | 1 C0023895 | liver disease | 1 C0027051 | myocardial infarction | 1 C0026896 | myasthenia gravis | 1 C0032993 | prolonged pregnancy | 1 C0022658 | kidney diseases | 1 C0149931 | migraine | 1 C0028866 | third nerve palsy | 1 C0023895 | liver diseases | 1 C0007194 | hypertrophic cardiomyopathy | 1 C0002871 | anaemia | 1 C0085697 | chronic pyelonephritis | 1 C0011615 | atopic dermatitis | 1 C0034186 | pyelonephritis | 1 C0042373 | vascular diseases | 1 C0035078 | kidney failure | 1 C0034063 | lung edema | 1 C0343386 | clostridium difficile infection | 1 C0035258 | restless legs syndrome | 1 C0037315 | sleep apnea | 1 C0020545 | renovascular hypertension | 1 C0006287 | bronchopulmonary dysplasia | 1 C0007222 | cardiovascular diseases | 1 C0398623 | thrombophilia | 1 C0027051 | myocardial infarct | 1 C0271355 | abducens nerve palsy | 1 C0152095 | trisomy 13 | 1 C0001973 | alcoholism | 1 C0030446 | paralytic ileus | 1 C0008148 | chlamydia | 1 |
Curated Gene | Entrez_id | Symbol | Resource(Total Genes:19) 1356 | CP | CTD_human 3162 | HMOX1 | CTD_human 4846 | NOS3 | CTD_human 6337 | SCNN1A | CTD_human 2259 | FGF14 | GWASCAT 1636 | ACE | CTD_human 183 | AGT | CTD_human 1906 | EDN1 | CTD_human 2052 | EPHX1 | CTD_human;GHR 308 | ANXA5 | CTD_human 5054 | SERPINE1 | CTD_human 219736 | STOX1 | CTD_human;ORPHANET;GHR 150142 | ZNF295-AS1 | GWASCAT 10699 | CORIN | ORPHANET;GHR 3624 | INHBA | CTD_human 2321 | FLT1 | CTD_human 23564 | DDAH2 | CTD_human 5177 | PEE1 | CTD_human;OMIM 23077 | MYCBP2 | GWASCAT |
Inferring Gene | Entrez_id | Symbol | Resource(Total Genes:131) 1636 | ACE | CIPHER;CTD_human 9370 | ADIPOQ | CIPHER 155 | ADRB3 | CIPHER 183 | AGT | CIPHER;CTD_human 185 | AGTR1 | CIPHER 186 | AGTR2 | CIPHER 308 | ANXA5 | CIPHER;CTD_human 348 | APOE | CIPHER 929 | CD14 | CIPHER 1277 | COL1A1 | CIPHER 1361 | CPB2 | CIPHER 1493 | CTLA4 | CIPHER 1543 | CYP1A1 | CIPHER 1565 | CYP2D6 | CIPHER 1571 | CYP2E1 | CIPHER 23576 | DDAH1 | CIPHER 1815 | DRD4 | CIPHER 1909 | EDNRA | CIPHER 5167 | ENPP1 | CIPHER 2052 | EPHX1 | CIPHER;CTD_human 2099 | ESR1 | CIPHER 2100 | ESR2 | CIPHER 2162 | F13A1 | CIPHER 2147 | F2 | CIPHER 2153 | F5 | CIPHER 2155 | F7 | CIPHER 355 | FAS | CIPHER 356 | FASLG | CIPHER 2244 | FGB | CIPHER 2944 | GSTM1 | CIPHER 2950 | GSTP1 | CIPHER 2952 | GSTT1 | CIPHER 3030 | HADHA | CIPHER 3105 | HLA-A | CIPHER 3117 | HLA-DQA1 | CIPHER 3119 | HLA-DQB1 | CIPHER 3123 | HLA-DRB1 | CIPHER 3135 | HLA-G | CIPHER 3240 | HP | CIPHER 3303 | HSPA1A | CIPHER 3304 | HSPA1B | CIPHER 3305 | HSPA1L | CIPHER 3458 | IFNG | CIPHER 3479 | IGF1 | CIPHER 3586 | IL10 | CIPHER 3552 | IL1A | CIPHER 3557 | IL1RN | CIPHER 3566 | IL4R | CIPHER 3569 | IL6 | CIPHER 3623 | INHA | CIPHER 3690 | ITGB3 | CIPHER 3805 | KIR2DL4 | CIPHER 3952 | LEP | CIPHER 3953 | LEPR | CIPHER 4023 | LPL | CIPHER 4314 | MMP3 | CIPHER 4318 | MMP9 | CIPHER 4353 | MPO | CIPHER 4524 | MTHFR | CIPHER 4567 | MT-TL1 | CIPHER 10 | NAT2 | CIPHER 4846 | NOS3 | CIPHER;CTD_human 4306 | NR3C2 | CIPHER 5444 | PON1 | CIPHER 5547 | PRCP | CIPHER 5972 | REN | CIPHER 6338 | SCNN1B | CIPHER 5054 | SERPINE1 | CIPHER;CTD_human 6648 | SOD2 | CIPHER 219736 | STOX1 | CIPHER;CTD_human 6890 | TAP1 | CIPHER 6891 | TAP2 | CIPHER 7040 | TGFB1 | CIPHER 7056 | THBD | CIPHER 7124 | TNF | CIPHER 7422 | VEGFA | CIPHER 92 | ACVR2A | CIPHER 328 | APEX1 | CIPHER 11132 | CAPN10 | CIPHER 3075 | CFH | CIPHER 1312 | COMT | CIPHER 1524 | CX3CR1 | CIPHER 1585 | CYP11B2 | CIPHER 1586 | CYP17A1 | CIPHER 1906 | EDN1 | CIPHER;CTD_human 1950 | EGF | CIPHER 2022 | ENG | CIPHER 2068 | ERCC2 | CIPHER 2321 | FLT1 | CIPHER;CTD_human 2324 | FLT4 | CIPHER 2492 | FSHR | CIPHER 2784 | GNB3 | CIPHER 2868 | GRK4 | CIPHER 283120 | H19 | CIPHER 3091 | HIF1A | CIPHER 3113 | HLA-DPA1 | CIPHER 3620 | IDO1 | CIPHER 3459 | IFNGR1 | CIPHER 3553 | IL1B | CIPHER 3565 | IL4 | CIPHER 3630 | INS | CIPHER 3643 | INSR | CIPHER 3667 | IRS1 | CIPHER 3674 | ITGA2B | CIPHER 3812 | KIR3DL2 | CIPHER 3990 | LIPC | CIPHER 4153 | MBL2 | CIPHER 1728 | NQO1 | CIPHER 5468 | PPARG | CIPHER 9475 | ROCK2 | CIPHER 6550 | SLC9A3 | CIPHER 6647 | SOD1 | CIPHER 7039 | TGFA | CIPHER 7054 | TH | CIPHER 7097 | TLR2 | CIPHER 7099 | TLR4 | CIPHER 10673 | TNFSF13B | CIPHER 10911 | UTS2 | CIPHER 7423 | VEGFB | CIPHER 7424 | VEGFC | CIPHER 7450 | VWF | CIPHER 7515 | XRCC1 | CIPHER 3162 | HMOX1 | CTD_human 780908 | PEE2 | CTD_human 780909 | PEE3 | CTD_human 3624 | INHBA | CTD_human 23526 | HMHA1 | CTD_human 23564 | DDAH2 | CTD_human 5177 | PEE1 | CTD_human 1356 | CP | CTD_human 6337 | SCNN1A | CTD_human |
Text Mined Gene | Entrez_id | Symbol | Score | Resource(Total Genes:325) 2 | A2M | 1.409 | DISEASES 19 | ABCA1 | 1.352 | DISEASES 60 | ACTB | 2.685 | DISEASES 93 | ACVR2B | 1.608 | DISEASES 8038 | ADAM12 | 4.488 | DISEASES 11085 | ADAM30 | 1.296 | DISEASES 81792 | ADAMTS12 | 2.367 | DISEASES 11093 | ADAMTS13 | 3.149 | DISEASES 9370 | ADIPOQ | 3.384 | DISEASES 79924 | ADM2 | 1.37 | DISEASES 155 | ADRB3 | 1.09 | DISEASES 174 | AFP | 3.632 | DISEASES 183 | AGT | 4.781 | DISEASES 186 | AGTR2 | 2.477 | DISEASES 197 | AHSG | 1.227 | DISEASES 8644 | AKR1C3 | 1.128 | DISEASES 283 | ANG | 2.39 | DISEASES 284 | ANGPT1 | 2.848 | DISEASES 353322 | ANKRD37 | 2.099 | DISEASES 302 | ANXA2 | 2.041 | DISEASES 221079 | ARL5B | 1.705 | DISEASES 405 | ARNT | 1.654 | DISEASES 408 | ARRB1 | 2.482 | DISEASES 51666 | ASB4 | 1.445 | DISEASES 430 | ASCL2 | 1.016 | DISEASES 23192 | ATG4B | 1.378 | DISEASES 10159 | ATP6AP2 | 1.556 | DISEASES 551 | AVP | 2.494 | DISEASES 567 | B2M | 1.755 | DISEASES 25825 | BACE2 | 1.105 | DISEASES 153579 | BTNL9 | 1.569 | DISEASES 716 | C1S | 1.036 | DISEASES 721 | C4B | 1.389 | DISEASES 730 | C7 | 1.341 | DISEASES 23705 | CADM1 | 1.62 | DISEASES 10203 | CALCRL | 2.413 | DISEASES 801 | CALM1 | 1.063 | DISEASES 813 | CALU | 1.109 | DISEASES 834 | CASP1 | 1.164 | DISEASES 841 | CASP8 | 1.022 | DISEASES 857 | CAV1 | 1.208 | DISEASES 875 | CBS | 1.998 | DISEASES 9332 | CD163 | 1.43 | DISEASES 930 | CD19 | 1.12 | DISEASES 911 | CD1C | 1.066 | DISEASES 4345 | CD200 | 1.062 | DISEASES 940 | CD28 | 1.224 | DISEASES 958 | CD40 | 1.153 | DISEASES 959 | CD40LG | 3.227 | DISEASES 966 | CD59 | 1.416 | DISEASES 1003 | CDH5 | 2.772 | DISEASES 1028 | CDKN1C | 2.529 | DISEASES 629 | CFB | 1.795 | DISEASES 1675 | CFD | 1.283 | DISEASES 3075 | CFH | 1.384 | DISEASES 94115 | CGB8 | 1.705 | DISEASES 91612 | CHURC1 | 1.775 | DISEASES 170482 | CLEC4C | 1.784 | DISEASES 9022 | CLIC3 | 1.951 | DISEASES 1266 | CNN3 | 1.158 | DISEASES 728577 | CNTNAP3B | 1.452 | DISEASES 22796 | COG2 | 2.055 | DISEASES 1307 | COL16A1 | 1.114 | DISEASES 80781 | COL18A1 | 1.492 | DISEASES 1284 | COL4A2 | 1.944 | DISEASES 1312 | COMT | 3.027 | DISEASES 1369 | CPN1 | 1.544 | DISEASES 27297 | CRCP | 1.191 | DISEASES 1394 | CRHR1 | 1.107 | DISEASES 1400 | CRMP1 | 1.08 | DISEASES 1443 | CSH2 | 4.096 | DISEASES 1471 | CST3 | 2.684 | DISEASES 1486 | CTBS | 4.085 | DISEASES 1491 | CTH | 2.263 | DISEASES 29119 | CTNNA3 | 1.775 | DISEASES 1506 | CTRL | 1.784 | DISEASES 404093 | CUEDC1 | 1.842 | DISEASES 6387 | CXCL12 | 1.418 | DISEASES 1585 | CYP11B2 | 2.526 | DISEASES 1573 | CYP2J2 | 2.098 | DISEASES 3491 | CYR61 | 2.259 | DISEASES 147906 | DACT3 | 1.174 | DISEASES 28988 | DBNL | 1.104 | DISEASES 23564 | DDAH2 | 2.414 | DISEASES 9704 | DHX34 | 1.588 | DISEASES 28514 | DLL1 | 1.103 | DISEASES 1747 | DLX3 | 1.041 | DISEASES 9166 | EBAG9 | 1.133 | DISEASES 1889 | ECE1 | 1.204 | DISEASES 1906 | EDN1 | 5.049 | DISEASES 1907 | EDN2 | 1.495 | DISEASES 1910 | EDNRB | 1.729 | DISEASES 2022 | ENG | 6.175 | DISEASES 219670 | ENKUR | 2.086 | DISEASES 2050 | EPHB4 | 2.134 | DISEASES 64167 | ERAP2 | 2.813 | DISEASES 405754 | ERVFRD-1 | 3.813 | DISEASES 100271846 | ERVV-2 | 1.829 | DISEASES 30816 | ERVW-1 | 3.14 | DISEASES 11082 | ESM1 | 2.046 | DISEASES 2104 | ESRRG | 1.334 | DISEASES 132884 | EVC2 | 1.547 | DISEASES 2149 | F2R | 1.518 | DISEASES 2152 | F3 | 4.037 | DISEASES 2153 | F5 | 3.222 | DISEASES 2155 | F7 | 2.024 | DISEASES 2157 | F8 | 1.542 | DISEASES 387742 | FAM99A | 2.164 | DISEASES 355 | FAS | 1.025 | DISEASES 356 | FASLG | 2.141 | DISEASES 2209 | FCGR1A | 1.661 | DISEASES 2214 | FCGR3A | 2.279 | DISEASES 8823 | FGF16 | 1.535 | DISEASES 2268 | FGR | 3.49 | DISEASES 2316 | FLNA | 1.408 | DISEASES 2335 | FN1 | 1.361 | DISEASES 50943 | FOXP3 | 2.696 | DISEASES 2621 | GAS6 | 1.697 | DISEASES 2638 | GC | 1.15 | DISEASES 2689 | GH2 | 1.34 | DISEASES 2811 | GP1BA | 1.085 | DISEASES 2876 | GPX1 | 1.393 | DISEASES 2878 | GPX3 | 1.813 | DISEASES 2879 | GPX4 | 1.485 | DISEASES 2938 | GSTA1 | 1.322 | DISEASES 2950 | GSTP1 | 1.46 | DISEASES 404672 | GTF2H5 | 1.19 | DISEASES 3033 | HADH | 1.266 | DISEASES 3030 | HADHA | 5.861 | DISEASES 3039 | HBA1 | 2.526 | DISEASES 3055 | HCK | 2.203 | DISEASES 352990 | HCP5B | 1.478 | DISEASES 101101692 | HELLPAR | 3.385 | DISEASES 3091 | HIF1A | 3.394 | DISEASES 3105 | HLA-A | 1.96 | DISEASES 3106 | HLA-B | 1.128 | DISEASES 3107 | HLA-C | 3.472 | DISEASES 3133 | HLA-E | 2.606 | DISEASES 3135 | HLA-G | 4.963 | DISEASES 3146 | HMGB1 | 1.967 | DISEASES 3240 | HP | 3.386 | DISEASES 3283 | HSD3B1 | 1.571 | DISEASES 3309 | HSPA5 | 1.633 | DISEASES 3316 | HSPB2 | 1.708 | DISEASES 3363 | HTR7 | 2.145 | DISEASES 5654 | HTRA1 | 1.495 | DISEASES 3384 | ICAM2 | 1.053 | DISEASES 414328 | IDNK | 1.459 | DISEASES 3620 | IDO1 | 1.274 | DISEASES 3481 | IGF2 | 2.494 | DISEASES 3486 | IGFBP3 | 2.253 | DISEASES 8518 | IKBKAP | 1.349 | DISEASES 3586 | IL10 | 3.84 | DISEASES 3605 | IL17A | 2.416 | DISEASES 133396 | IL31RA | 1.649 | DISEASES 90865 | IL33 | 1.255 | DISEASES 3640 | INSL3 | 1.496 | DISEASES 11172 | INSL6 | 1.187 | DISEASES 3676 | ITGA4 | 2.061 | DISEASES 3683 | ITGAL | 1.236 | DISEASES 3684 | ITGAM | 2.29 | DISEASES 9358 | ITGBL1 | 1.272 | DISEASES 9452 | ITM2A | 1.026 | DISEASES 23210 | JMJD6 | 1.664 | DISEASES 3725 | JUN | 1.077 | DISEASES 102723508 | KANTR | 2.23 | DISEASES 3767 | KCNJ11 | 1.217 | DISEASES 3802 | KIR2DL1 | 1.476 | DISEASES 3805 | KIR2DL4 | 2.365 | DISEASES 3811 | KIR3DL1 | 1.085 | DISEASES 3812 | KIR3DL2 | 1.962 | DISEASES 3814 | KISS1 | 3.205 | DISEASES 9365 | KL | 1.064 | DISEASES 11279 | KLF8 | 1.186 | DISEASES 9622 | KLK4 | 2.544 | DISEASES 3821 | KLRC1 | 1.245 | DISEASES 3822 | KLRC2 | 1.453 | DISEASES 3824 | KLRD1 | 1.347 | DISEASES 100506243 | KRBOX1 | 2.603 | DISEASES 3875 | KRT18 | 2.054 | DISEASES 3855 | KRT7 | 2.235 | DISEASES 51520 | LARS | 1.463 | DISEASES 3939 | LDHA | 1.63 | DISEASES 3953 | LEPR | 2.112 | DISEASES 56891 | LGALS14 | 2.331 | DISEASES 148003 | LGALS16 | 2.547 | DISEASES 3980 | LIG3 | 1.507 | DISEASES 4018 | LPA | 1.877 | DISEASES 53353 | LRP1B | 2.505 | DISEASES 347731 | LRRTM3 | 1.156 | DISEASES 4049 | LTA | 1.049 | DISEASES 130574 | LYPD6 | 1.496 | DISEASES 57134 | MAN1C1 | 1.101 | DISEASES 4128 | MAOA | 1.049 | DISEASES 5599 | MAPK8 | 1.16 | DISEASES 4153 | MBL2 | 1.192 | DISEASES 84879 | MFSD2A | 1.093 | DISEASES 8972 | MGAM | 3.482 | DISEASES 10724 | MGEA5 | 1.546 | DISEASES 100073347 | MIMT1 | 1.081 | DISEASES 4312 | MMP1 | 2.304 | DISEASES 4318 | MMP9 | 3.611 | DISEASES 57504 | MTA3 | 1.347 | DISEASES 4524 | MTHFR | 4.643 | DISEASES 4648 | MYO7B | 1.55 | DISEASES 400746 | NCMAP | 1.543 | DISEASES 55967 | NDUFA12 | 1.026 | DISEASES 4780 | NFE2L2 | 1.941 | DISEASES 114548 | NLRP3 | 1.029 | DISEASES 4843 | NOS2 | 1.425 | DISEASES 115677 | NOSTRIN | 2.596 | DISEASES 4855 | NOTCH4 | 1.059 | DISEASES 4868 | NPHS1 | 3.268 | DISEASES 7827 | NPHS2 | 2.653 | DISEASES 4878 | NPPA | 1.296 | DISEASES 4879 | NPPB | 2.042 | DISEASES 10062 | NR1H3 | 1.748 | DISEASES 100506658 | OCLN | 1.067 | DISEASES 203569 | PAGE2 | 1.711 | DISEASES 5069 | PAPPA | 6.311 | DISEASES 60676 | PAPPA2 | 4.668 | DISEASES 56034 | PDGFC | 1.051 | DISEASES 553115 | PEF1 | 2.371 | DISEASES 23089 | PEG10 | 1.449 | DISEASES 5228 | PGF | 7.377 | DISEASES 55361 | PI4K2A | 1.309 | DISEASES 5294 | PIK3CG | 1.951 | DISEASES 10761 | PLAC1 | 3.487 | DISEASES 191585 | PLAC4 | 3.137 | DISEASES 5329 | PLAUR | 1.073 | DISEASES 5406 | PNLIP | 2.729 | DISEASES 5420 | PODXL | 1.506 | DISEASES 9374 | PPT2 | 1.521 | DISEASES 5547 | PRCP | 1.273 | DISEASES 10216 | PRG4 | 2.597 | DISEASES 8842 | PROM1 | 1.181 | DISEASES 5671 | PSG3 | 1.473 | DISEASES 5672 | PSG4 | 1.141 | DISEASES 5742 | PTGS1 | 1.765 | DISEASES 5743 | PTGS2 | 1.926 | DISEASES 5788 | PTPRC | 1.513 | DISEASES 284119 | PTRF | 1.329 | DISEASES 9364 | RAB28 | 1.071 | DISEASES 11186 | RASSF1 | 2.099 | DISEASES 5950 | RBP4 | 2.07 | DISEASES 112724 | RDH13 | 1.687 | DISEASES 6007 | RHD | 2.004 | DISEASES 6019 | RLN2 | 1.886 | DISEASES 6093 | ROCK1 | 1.6 | DISEASES 84268 | RPAIN | 1.32 | DISEASES 23212 | RRS1 | 1.954 | DISEASES 795 | S100G | 1.401 | DISEASES 23328 | SASH1 | 1.301 | DISEASES 677780 | SCARNA11 | 2.502 | DISEASES 6401 | SELE | 3.753 | DISEASES 8991 | SELENBP1 | 1.268 | DISEASES 57556 | SEMA6A | 1.024 | DISEASES 5265 | SERPINA1 | 1.79 | DISEASES 5104 | SERPINA5 | 1.021 | DISEASES 866 | SERPINA6 | 1.175 | DISEASES 6906 | SERPINA7 | 1.621 | DISEASES 5268 | SERPINB5 | 1.186 | DISEASES 462 | SERPINC1 | 5.053 | DISEASES 5345 | SERPINF2 | 2.51 | DISEASES 871 | SERPINH1 | 4.113 | DISEASES 10603 | SH2B2 | 1.322 | DISEASES 9467 | SH3BP5 | 1.344 | DISEASES 9644 | SH3PXD2A | 1.306 | DISEASES 6462 | SHBG | 2.621 | DISEASES 946 | SIGLEC6 | 3.911 | DISEASES 117247 | SLC16A10 | 1.818 | DISEASES 6510 | SLC1A5 | 1.301 | DISEASES 57419 | SLC24A3 | 1.729 | DISEASES 6513 | SLC2A1 | 1.026 | DISEASES 254428 | SLC41A1 | 1.917 | DISEASES 54946 | SLC41A3 | 2.251 | DISEASES 6546 | SLC8A1 | 1.581 | DISEASES 139065 | SLITRK4 | 1.55 | DISEASES 677837 | SNORA60 | 2.502 | DISEASES 9021 | SOCS3 | 1.129 | DISEASES 10580 | SORBS1 | 1.065 | DISEASES 6676 | SPAG4 | 1.39 | DISEASES 139886 | SPIN4 | 1.94 | DISEASES 6692 | SPINT1 | 1.355 | DISEASES 100642175 | SPRY4-IT1 | 1.898 | DISEASES 6710 | SPTB | 3.502 | DISEASES 27286 | SRPX2 | 1.878 | DISEASES 6736 | SRY | 2.433 | DISEASES 6772 | STAT1 | 1.218 | DISEASES 7341 | SUMO1 | 1.306 | DISEASES 85360 | SYDE1 | 2.189 | DISEASES 84144 | SYDE2 | 2.059 | DISEASES 11346 | SYNPO | 1.593 | DISEASES 6863 | TAC1 | 1.071 | DISEASES 6949 | TCOF1 | 1.249 | DISEASES 7005 | TEAD3 | 1.318 | DISEASES 7010 | TEK | 2.536 | DISEASES 7018 | TF | 1.87 | DISEASES 7037 | TFRC | 1.454 | DISEASES 7042 | TGFB2 | 1.415 | DISEASES 7056 | THBD | 3.803 | DISEASES 7099 | TLR4 | 2.795 | DISEASES 54106 | TLR9 | 1.139 | DISEASES 79022 | TMEM106C | 3.624 | DISEASES 131920 | TMEM207 | 1.306 | DISEASES 7124 | TNF | 4.425 | DISEASES 7133 | TNFRSF1B | 1.135 | DISEASES 7137 | TNNI3 | 1.7 | DISEASES 6399 | TRAPPC2 | 1.689 | DISEASES 140803 | TRPM6 | 1.274 | DISEASES 55503 | TRPV6 | 1.334 | DISEASES 7106 | TSPAN4 | 1.461 | DISEASES 7258 | TSPY1 | 2.84 | DISEASES 100289087 | TSPY10 | 2.732 | DISEASES 7295 | TXN | 1.512 | DISEASES 51366 | UBR5 | 1.282 | DISEASES 114131 | UCN3 | 1.537 | DISEASES 23376 | UFL1 | 1.128 | DISEASES 25972 | UNC50 | 1.548 | DISEASES 57216 | VANGL2 | 4.643 | DISEASES 7421 | VDR | 2.125 | DISEASES 7422 | VEGFA | 5.172 | DISEASES 11326 | VSIG4 | 2.036 | DISEASES 23038 | WDTC1 | 2.617 | DISEASES 100128252 | ZNF667-AS1 | 1.551 | DISEASES |
Locus | (Waiting for update.) |
Disease ID | 182 |
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Disease | pre-eclampsia |
Manually Symptom | UMLS | Name(Total Manually Symptoms:53) C2364133 | infection C2364072 | depression C1963229 | retinal detachment C1963138 | hypertension C1962972 | proteinuria C1962958 | hematoma C1959583 | myocardial failure C1660219 | analgesia C1412610 | antithrombin iii deficiency C1405749 | hepatorenal syndrome C1402315 | vascular lesions C1268935 | microangiopathic hemolytic anemia C1142517 | lupus anticoagulant C0948265 | metabolic syndrome C0917798 | cerebral ischaemia C0877035 | oestrogenic effect C0856169 | endothelial dysfunction C0796095 | c syndrome C0752303 | urological manifestations C0740394 | hyperuricemia C0730345 | microalbuminuria C0553681 | hypofibrinogenaemia C0456909 | blindness C0398623 | hypercoagulable state C0392549 | cerebral palsy C0376288 | amaurosis C0341697 | renal impairment C0271355 | abducens nerve palsy C0269286 | rudimentary horn pregnancy C0162429 | malnutrition C0155320 | cortical blindness C0151864 | pregnancy disorder C0085616 | vasospasm C0040034 | thrombocytopenia C0035305 | retinal detachments C0034063 | pulmonary edema C0032227 | pleural effusions C0032051 | placental insufficiency C0031190 | fetal circulation C0028961 | oliguria C0022116 | ischemia C0021308 | infarction C0020649 | hypotension C0020625 | hyponatremia C0020599 | hypocalciuria C0020538 | high blood pressure C0019270 | herniation C0018681 | headaches C0017668 | focal glomerular sclerosis C0015930 | foetal distress C0015927 | intrauterine death C0012739 | disseminated intravascular coagulation C0000832 | abruptio placentae |
Text Mined Symptom | UMLS | Name | Sentences' Count(Total Symptoms:27) C0020538 | hypertension | 43 C0033687 | proteinuria | 16 C0856169 | endothelial dysfunction | 13 C0162739 | hellp syndrome | 11 C0036572 | seizures | 8 C0340274 | gestational hypertension | 5 C0032051 | placental insufficiency | 3 C0040034 | thrombocytopenia | 3 C0032962 | pregnancy complications | 3 C0035309 | retinopathy | 2 C0740394 | hyperuricemia | 2 C0040053 | thrombosis | 2 C0547030 | visual disturbance | 2 C0042396 | vasospasm | 1 C0000832 | placental abruption | 1 C0015934 | fetal growth retardation | 1 C0009951 | convulsions | 1 C0028961 | oliguria | 1 C0024141 | le syndrome | 1 C0023895 | liver disease | 1 C0019080 | hemorrhage | 1 C0022658 | nephropathy | 1 C1455728 | fatty liver of pregnancy | 1 C0038454 | stroke | 1 C0020598 | hypoglycemia | 1 C0494475 | grand mal seizures | 1 C0034063 | pulmonary edema | 1 |
Manually Genotype(Total Text Mining Genotypes:0) |
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(Waiting for update.) |
Text Mining Genotype(Total Genotypes:0) | |
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(Waiting for update.) |
All Snps(Total Genotypes:3) | |||||||||||||
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snpId | pubmedId | geneId | geneSymbol | diseaseId | sourceId | sentence | score | Year | geneSymbol_dbSNP | CHROMOSOME | POS | REF | ALT |
rs11617740 | 23551011 | 2259 | FGF14 | umls:C0032914 | GWASCAT | Genome-wide association study of pre-eclampsia detects novel maternal single nucleotide polymorphisms and copy-number variants in subsets of the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) study cohort. | 0.12 | 2013 | FGF14 | 13 | 102027776 | G | A |
rs2839440 | 23551011 | 150142 | ZNF295-AS1 | umls:C0032914 | GWASCAT | Genome-wide association study of pre-eclampsia detects novel maternal single nucleotide polymorphisms and copy-number variants in subsets of the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) study cohort. | 0.12 | 2013 | ZNF295-AS1 | 21 | 42023389 | C | T |
rs7322722 | 23551011 | 23077 | MYCBP2 | umls:C0032914 | GWASCAT | Genome-wide association study of pre-eclampsia detects novel maternal single nucleotide polymorphisms and copy-number variants in subsets of the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) study cohort. | 0.12 | 2013 | MYCBP2 | 13 | 77305241 | G | A |
GWASdb Annotation(Total Genotypes:0) | |
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(Waiting for update.) |
GWASdb Snp Trait(Total Genotypes:49) | |||||||||||||||||||||||||||||
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CHR | POS | SNPID | REF | ALT | ORI_SNPID | PMID | P_VALUE | P_VALUE_TEXT | OR/BETA | CI95_TEXT | GWAS_INITIAL_SAMPLE_SIZE | SUB_POPULATION | SUPER_POPULATION | GWAS_TRAIT | HPO_ID | HPO_TERM | DO_ID | DO_TERM | MESH_ID | MESH_TERM | EFO_ID | EFO_TERM | DOLITE_TERM | RISK_ALLELE | PUBLICATION_TYPE | AA | GENE_SYMBOL | TYPE | REFGENE |
1 | 217185265 | rs17686866 | C | A | rs17686866 | 22748001 | 0.0000038 | NA | NA | NA | 293 Caucasian females | Caucasian(293) | ALL(293) | EUR(293) | ALL(293) | Preeclampsia | HPOID:0100602 | Preeclampsia | DOID:10591 | pre-eclampsia | D011225 | Pre-Eclampsia | NA | NA | Pre-Eclampsia | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | C |
1 | 217185265 | rs17686866 | C | A | rs17686866 | 23551011 | 8.99E-06 | Caucasian | 2.78 | [1.79-4.35] | 21 Afro-Caribbean cases; 1,010 Afro-Caribbean controls; 50 European ancestry cases; 1,202 European ancestry controls; 62 Hispanic cases; 658 Hispanic controls | Afro-Caribbean(1031) | European(1252) | Hispanic(720) | ALL(3003) | HIS(720) | AFR(1031) | EUR(1252) | ALL(3003) | Preeclampsia | HPOID:0100602 | Preeclampsia | DOID:10591 | pre-eclampsia | D011225 | Pre-Eclampsia | NA | NA | Pre-Eclampsia |
1 | 224916592 | rs6660579 | C | T | rs6660579 | 22432041 | 0.0000078 | NA | NA | NA | 538 European ancestry cases; 540 European ancestry controls | European(1078) | ALL(1078) | EUR(1078) | ALL(1078) | Preeclampsia | HPOID:0100602 | Preeclampsia | DOID:10591 | pre-eclampsia | D011225 | Pre-Eclampsia | NA | NA | Pre-Eclampsia | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | C |
2 | 26322040 | rs9332419 | A | G | rs9332419 | 22432041 | 0.00000617 | NA | NA | NA | 538 European ancestry cases; 540 European ancestry controls | European(1078) | ALL(1078) | EUR(1078) | ALL(1078) | Preeclampsia | HPOID:0100602 | Preeclampsia | DOID:10591 | pre-eclampsia | D011225 | Pre-Eclampsia | NA | NA | Pre-Eclampsia | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A |
2 | 26344787 | rs11126375 | G | A | rs11126375 | 22432041 | 0.00000913 | NA | NA | NA | 538 European ancestry cases; 540 European ancestry controls | European(1078) | ALL(1078) | EUR(1078) | ALL(1078) | Preeclampsia | HPOID:0100602 | Preeclampsia | DOID:10591 | pre-eclampsia | D011225 | Pre-Eclampsia | NA | NA | Pre-Eclampsia | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A |
2 | 46746963 | rs4952830 | A | G | rs4952830 | 22432041 | 0.00000674 | NA | NA | NA | 538 European ancestry cases; 540 European ancestry controls | European(1078) | ALL(1078) | EUR(1078) | ALL(1078) | Preeclampsia | HPOID:0100602 | Preeclampsia | DOID:10591 | pre-eclampsia | D011225 | Pre-Eclampsia | NA | NA | Pre-Eclampsia | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A |
2 | 105877870 | rs17636747 | C | T | rs17636747 | 23551011 | 4.00E-06 | Hispanic | 8.35 | [3.41-20.46] | 21 Afro-Caribbean cases; 1,010 Afro-Caribbean controls; 50 European ancestry cases; 1,202 European ancestry controls; 62 Hispanic cases; 658 Hispanic controls | Afro-Caribbean(1031) | European(1252) | Hispanic(720) | ALL(3003) | HIS(720) | AFR(1031) | EUR(1252) | ALL(3003) | Preeclampsia | HPOID:0100602 | Preeclampsia | DOID:10591 | pre-eclampsia | D011225 | Pre-Eclampsia | NA | NA | Pre-Eclampsia |
2 | 108415702 | rs6542736 | G | A | rs6542736 | 22432041 | 0.00000731 | NA | NA | NA | 538 European ancestry cases; 540 European ancestry controls | European(1078) | ALL(1078) | EUR(1078) | ALL(1078) | Preeclampsia | HPOID:0100602 | Preeclampsia | DOID:10591 | pre-eclampsia | D011225 | Pre-Eclampsia | NA | NA | Pre-Eclampsia | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G |
2 | 121118031 | rs7576192 | A | G | rs7576192 | 22432041 | 0.000000148 | NA | NA | NA | 538 European ancestry cases; 540 European ancestry controls | European(1078) | ALL(1078) | EUR(1078) | ALL(1078) | Preeclampsia | HPOID:0100602 | Preeclampsia | DOID:10591 | pre-eclampsia | D011225 | Pre-Eclampsia | NA | NA | Pre-Eclampsia | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G |
2 | 121118124 | rs7579169 | T | C | rs7579169 | 22432041 | 0.000000358 | NA | NA | NA | 538 European ancestry cases; 540 European ancestry controls | European(1078) | ALL(1078) | EUR(1078) | ALL(1078) | Preeclampsia | HPOID:0100602 | Preeclampsia | DOID:10591 | pre-eclampsia | D011225 | Pre-Eclampsia | NA | NA | Pre-Eclampsia | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | C |
2 | 121123383 | rs12711941 | T | G | rs12711941 | 22432041 | 0.000000426 | NA | NA | NA | 538 European ancestry cases; 540 European ancestry controls | European(1078) | ALL(1078) | EUR(1078) | ALL(1078) | Preeclampsia | HPOID:0100602 | Preeclampsia | DOID:10591 | pre-eclampsia | D011225 | Pre-Eclampsia | NA | NA | Pre-Eclampsia | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G |
3 | 8571110 | rs9831647 | G | A | rs9831647 | 22748001 | 0.00000936 | NA | NA | NA | 293 Caucasian females | Caucasian(293) | ALL(293) | EUR(293) | ALL(293) | Preeclampsia | HPOID:0100602 | Preeclampsia | DOID:10591 | pre-eclampsia | D011225 | Pre-Eclampsia | NA | NA | Pre-Eclampsia | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G |
3 | 87257423 | rs17024019 | A | G | rs17024019 | 22432041 | 0.00000957 | NA | NA | NA | 538 European ancestry cases; 540 European ancestry controls | European(1078) | ALL(1078) | EUR(1078) | ALL(1078) | Preeclampsia | HPOID:0100602 | Preeclampsia | DOID:10591 | pre-eclampsia | D011225 | Pre-Eclampsia | NA | NA | Pre-Eclampsia | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G |
3 | 87276699 | rs2279720 | C | T | rs2279720 | 22432041 | 0.00000866 | NA | NA | NA | 538 European ancestry cases; 540 European ancestry controls | European(1078) | ALL(1078) | EUR(1078) | ALL(1078) | Preeclampsia | HPOID:0100602 | Preeclampsia | DOID:10591 | pre-eclampsia | D011225 | Pre-Eclampsia | NA | NA | Pre-Eclampsia | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G |
3 | 87299075 | rs1044499 | A | C | rs1044499 | 22432041 | 0.00000866 | NA | NA | NA | 538 European ancestry cases; 540 European ancestry controls | European(1078) | ALL(1078) | EUR(1078) | ALL(1078) | Preeclampsia | HPOID:0100602 | Preeclampsia | DOID:10591 | pre-eclampsia | D011225 | Pre-Eclampsia | NA | NA | Pre-Eclampsia | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A |
3 | 149250589 | rs17787940 | T | C | rs17787940 | 23551011 | 3.00E-06 | EA | 3.17 | [1.95-5.16] | 21 Afro-Caribbean cases; 1,010 Afro-Caribbean controls; 50 European ancestry cases; 1,202 European ancestry controls; 62 Hispanic cases; 658 Hispanic controls | Afro-Caribbean(1031) | European(1252) | Hispanic(720) | ALL(3003) | HIS(720) | AFR(1031) | EUR(1252) | ALL(3003) | Preeclampsia | HPOID:0100602 | Preeclampsia | DOID:10591 | pre-eclampsia | D011225 | Pre-Eclampsia | NA | NA | Pre-Eclampsia |
4 | 37173944 | rs1426409 | G | A | rs1426409 | 22748001 | 0.00000314 | NA | NA | NA | 293 Caucasian females | Caucasian(293) | ALL(293) | EUR(293) | ALL(293) | Preeclampsia | HPOID:0100602 | Preeclampsia | DOID:10591 | pre-eclampsia | D011225 | Pre-Eclampsia | NA | NA | Pre-Eclampsia | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | T |
4 | 98965696 | rs7677523 | T | C | rs7677523 | 22432041 | 0.00000951 | NA | NA | NA | 538 European ancestry cases; 540 European ancestry controls | European(1078) | ALL(1078) | EUR(1078) | ALL(1078) | Preeclampsia | HPOID:0100602 | Preeclampsia | DOID:10591 | pre-eclampsia | D011225 | Pre-Eclampsia | NA | NA | Pre-Eclampsia | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | T |
4 | 182609865 | rs12641856 | G | A | rs12641856 | 23551011 | 2.00E-06 | Afro-Caribbean | 15.19 | [4.98-46.35] | 21 Afro-Caribbean cases; 1,010 Afro-Caribbean controls; 50 European ancestry cases; 1,202 European ancestry controls; 62 Hispanic cases; 658 Hispanic controls | Afro-Caribbean(1031) | European(1252) | Hispanic(720) | ALL(3003) | HIS(720) | AFR(1031) | EUR(1252) | ALL(3003) | Preeclampsia | HPOID:0100602 | Preeclampsia | DOID:10591 | pre-eclampsia | D011225 | Pre-Eclampsia | NA | NA | Pre-Eclampsia |
6 | 30976219 | rs28360974 | G | A | rs28360974 | 23551011 | 3.00E-06 | Afro-Caribbean | 10.13 | [3.85-26.67] | 21 Afro-Caribbean cases; 1,010 Afro-Caribbean controls; 50 European ancestry cases; 1,202 European ancestry controls; 62 Hispanic cases; 658 Hispanic controls | Afro-Caribbean(1031) | European(1252) | Hispanic(720) | ALL(3003) | HIS(720) | AFR(1031) | EUR(1252) | ALL(3003) | Preeclampsia | HPOID:0100602 | Preeclampsia | DOID:10591 | pre-eclampsia | D011225 | Pre-Eclampsia | NA | NA | Pre-Eclampsia |
7 | 25612661 | rs975369 | G | A | rs975369 | 23551011 | 8.00E-06 | Afro-Caribbean | 4.55 | [2.34-8.83] | 21 Afro-Caribbean cases; 1,010 Afro-Caribbean controls; 50 European ancestry cases; 1,202 European ancestry controls; 62 Hispanic cases; 658 Hispanic controls | Afro-Caribbean(1031) | European(1252) | Hispanic(720) | ALL(3003) | HIS(720) | AFR(1031) | EUR(1252) | ALL(3003) | Preeclampsia | HPOID:0100602 | Preeclampsia | DOID:10591 | pre-eclampsia | D011225 | Pre-Eclampsia | NA | NA | Pre-Eclampsia |
8 | 20246758 | rs17412740 | G | A | rs17412740 | 23551011 | 2.00E-06 | Hispanic | 6.08 | [2.88-12.81] | 21 Afro-Caribbean cases; 1,010 Afro-Caribbean controls; 50 European ancestry cases; 1,202 European ancestry controls; 62 Hispanic cases; 658 Hispanic controls | Afro-Caribbean(1031) | European(1252) | Hispanic(720) | ALL(3003) | HIS(720) | AFR(1031) | EUR(1252) | ALL(3003) | Preeclampsia | HPOID:0100602 | Preeclampsia | DOID:10591 | pre-eclampsia | D011225 | Pre-Eclampsia | NA | NA | Pre-Eclampsia |
8 | 20263408 | rs1016646 | G | A | rs1016646 | 23551011 | 9.45E-06 | Hispanic | 5.68 | [2.63-12.25] | 21 Afro-Caribbean cases; 1,010 Afro-Caribbean controls; 50 European ancestry cases; 1,202 European ancestry controls; 62 Hispanic cases; 658 Hispanic controls | Afro-Caribbean(1031) | European(1252) | Hispanic(720) | ALL(3003) | HIS(720) | AFR(1031) | EUR(1252) | ALL(3003) | Preeclampsia | HPOID:0100602 | Preeclampsia | DOID:10591 | pre-eclampsia | D011225 | Pre-Eclampsia | NA | NA | Pre-Eclampsia |
9 | 102808685 | rs7028939 | A | G | rs7028939 | 23551011 | 3.00E-06 | EA | 3.17 | [1.95-5.15] | 21 Afro-Caribbean cases; 1,010 Afro-Caribbean controls; 50 European ancestry cases; 1,202 European ancestry controls; 62 Hispanic cases; 658 Hispanic controls | Afro-Caribbean(1031) | European(1252) | Hispanic(720) | ALL(3003) | HIS(720) | AFR(1031) | EUR(1252) | ALL(3003) | Preeclampsia | HPOID:0100602 | Preeclampsia | DOID:10591 | pre-eclampsia | D011225 | Pre-Eclampsia | NA | NA | Pre-Eclampsia |
9 | 102854188 | rs7849323 | T | C | rs7849323 | 23551011 | 3.42E-06 | EA | 3.15 | [1.94-5.11] | 21 Afro-Caribbean cases; 1,010 Afro-Caribbean controls; 50 European ancestry cases; 1,202 European ancestry controls; 62 Hispanic cases; 658 Hispanic controls | Afro-Caribbean(1031) | European(1252) | Hispanic(720) | ALL(3003) | HIS(720) | AFR(1031) | EUR(1252) | ALL(3003) | Preeclampsia | HPOID:0100602 | Preeclampsia | DOID:10591 | pre-eclampsia | D011225 | Pre-Eclampsia | NA | NA | Pre-Eclampsia |
9 | 102911706 | rs1415927 | T | C | rs1415927 | 23551011 | 3.48E-06 | EA | 3.15 | [1.94-5.11] | 21 Afro-Caribbean cases; 1,010 Afro-Caribbean controls; 50 European ancestry cases; 1,202 European ancestry controls; 62 Hispanic cases; 658 Hispanic controls | Afro-Caribbean(1031) | European(1252) | Hispanic(720) | ALL(3003) | HIS(720) | AFR(1031) | EUR(1252) | ALL(3003) | Preeclampsia | HPOID:0100602 | Preeclampsia | DOID:10591 | pre-eclampsia | D011225 | Pre-Eclampsia | NA | NA | Pre-Eclampsia |
9 | 102918306 | rs7047693 | T | C | rs7047693 | 23551011 | 3.31E-06 | EA | 3.16 | [1.94-5.12] | 21 Afro-Caribbean cases; 1,010 Afro-Caribbean controls; 50 European ancestry cases; 1,202 European ancestry controls; 62 Hispanic cases; 658 Hispanic controls | Afro-Caribbean(1031) | European(1252) | Hispanic(720) | ALL(3003) | HIS(720) | AFR(1031) | EUR(1252) | ALL(3003) | Preeclampsia | HPOID:0100602 | Preeclampsia | DOID:10591 | pre-eclampsia | D011225 | Pre-Eclampsia | NA | NA | Pre-Eclampsia |
9 | 102922307 | rs10988989 | T | C | rs10988989 | 23551011 | 3.31E-06 | EA | 3.16 | [1.94-5.12] | 21 Afro-Caribbean cases; 1,010 Afro-Caribbean controls; 50 European ancestry cases; 1,202 European ancestry controls; 62 Hispanic cases; 658 Hispanic controls | Afro-Caribbean(1031) | European(1252) | Hispanic(720) | ALL(3003) | HIS(720) | AFR(1031) | EUR(1252) | ALL(3003) | Preeclampsia | HPOID:0100602 | Preeclampsia | DOID:10591 | pre-eclampsia | D011225 | Pre-Eclampsia | NA | NA | Pre-Eclampsia |
9 | 102958736 | rs7020780 | G | A | rs7020780 | 23551011 | 2.66E-06 | EA | 3.19 | [1.96-5.17] | 21 Afro-Caribbean cases; 1,010 Afro-Caribbean controls; 50 European ancestry cases; 1,202 European ancestry controls; 62 Hispanic cases; 658 Hispanic controls | Afro-Caribbean(1031) | European(1252) | Hispanic(720) | ALL(3003) | HIS(720) | AFR(1031) | EUR(1252) | ALL(3003) | Preeclampsia | HPOID:0100602 | Preeclampsia | DOID:10591 | pre-eclampsia | D011225 | Pre-Eclampsia | NA | NA | Pre-Eclampsia |
9 | 102976541 | rs10989019 | T | C | rs10989019 | 23551011 | 2.00E-06 | EA | 3.21 | [1.98-5.20] | 21 Afro-Caribbean cases; 1,010 Afro-Caribbean controls; 50 European ancestry cases; 1,202 European ancestry controls; 62 Hispanic cases; 658 Hispanic controls | Afro-Caribbean(1031) | European(1252) | Hispanic(720) | ALL(3003) | HIS(720) | AFR(1031) | EUR(1252) | ALL(3003) | Preeclampsia | HPOID:0100602 | Preeclampsia | DOID:10591 | pre-eclampsia | D011225 | Pre-Eclampsia | NA | NA | Pre-Eclampsia |
10 | 29027223 | rs1248993 | A | G | rs1248993 | 23551011 | 6.00E-06 | Afro-Caribbean | 4.27 | [2.28-8.01] | 21 Afro-Caribbean cases; 1,010 Afro-Caribbean controls; 50 European ancestry cases; 1,202 European ancestry controls; 62 Hispanic cases; 658 Hispanic controls | Afro-Caribbean(1031) | European(1252) | Hispanic(720) | ALL(3003) | HIS(720) | AFR(1031) | EUR(1252) | ALL(3003) | Preeclampsia | HPOID:0100602 | Preeclampsia | DOID:10591 | pre-eclampsia | D011225 | Pre-Eclampsia | NA | NA | Pre-Eclampsia |
10 | 105884116 | rs10883969 | C | T | rs10883969 | 23551011 | 3.00E-06 | EA | 2.97 | [1.88-4.69] | 21 Afro-Caribbean cases; 1,010 Afro-Caribbean controls; 50 European ancestry cases; 1,202 European ancestry controls; 62 Hispanic cases; 658 Hispanic controls | Afro-Caribbean(1031) | European(1252) | Hispanic(720) | ALL(3003) | HIS(720) | AFR(1031) | EUR(1252) | ALL(3003) | Preeclampsia | HPOID:0100602 | Preeclampsia | DOID:10591 | pre-eclampsia | D011225 | Pre-Eclampsia | NA | NA | Pre-Eclampsia |
11 | 118031986 | rs11600901 | G | A | rs11600901 | 23551011 | 9.00E-06 | Afro-Caribbean | 9.83 | [3.58-27.00] | 21 Afro-Caribbean cases; 1,010 Afro-Caribbean controls; 50 European ancestry cases; 1,202 European ancestry controls; 62 Hispanic cases; 658 Hispanic controls | Afro-Caribbean(1031) | European(1252) | Hispanic(720) | ALL(3003) | HIS(720) | AFR(1031) | EUR(1252) | ALL(3003) | Preeclampsia | HPOID:0100602 | Preeclampsia | DOID:10591 | pre-eclampsia | D011225 | Pre-Eclampsia | NA | NA | Pre-Eclampsia |
12 | 25660579 | rs10743565 | A | G | rs10743565 | 22748001 | 0.0000164 | NA | NA | NA | 293 Caucasian females | Caucasian(293) | ALL(293) | EUR(293) | ALL(293) | Preeclampsia | HPOID:0100602 | Preeclampsia | DOID:10591 | pre-eclampsia | D011225 | Pre-Eclampsia | NA | NA | Pre-Eclampsia | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A |
12 | 25660579 | rs10743565 | A | G | rs10743565 | 23551011 | 6.77E-06 | Caucasian | 2.44 | [1.67-3.70] | 21 Afro-Caribbean cases; 1,010 Afro-Caribbean controls; 50 European ancestry cases; 1,202 European ancestry controls; 62 Hispanic cases; 658 Hispanic controls | Afro-Caribbean(1031) | European(1252) | Hispanic(720) | ALL(3003) | HIS(720) | AFR(1031) | EUR(1252) | ALL(3003) | Preeclampsia | HPOID:0100602 | Preeclampsia | DOID:10591 | pre-eclampsia | D011225 | Pre-Eclampsia | NA | NA | Pre-Eclampsia |
13 | 39903243 | rs6563695 | G | T | rs6563695 | 23551011 | 5.00E-06 | EA | 3.65 | [2.09-6.36] | 21 Afro-Caribbean cases; 1,010 Afro-Caribbean controls; 50 European ancestry cases; 1,202 European ancestry controls; 62 Hispanic cases; 658 Hispanic controls | Afro-Caribbean(1031) | European(1252) | Hispanic(720) | ALL(3003) | HIS(720) | AFR(1031) | EUR(1252) | ALL(3003) | Preeclampsia | HPOID:0100602 | Preeclampsia | DOID:10591 | pre-eclampsia | D011225 | Pre-Eclampsia | NA | NA | Pre-Eclampsia |
13 | 77488736 | rs12431203 | G | A | rs12431203 | 22432041 | 0.00000245 | NA | NA | NA | 538 European ancestry cases; 540 European ancestry controls | European(1078) | ALL(1078) | EUR(1078) | ALL(1078) | Preeclampsia | HPOID:0100602 | Preeclampsia | DOID:10591 | pre-eclampsia | D011225 | Pre-Eclampsia | NA | NA | Pre-Eclampsia | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G |
13 | 77622818 | rs624575 | C | T | rs624575 | 23551011 | 1.50E-06 | EA | 2.9 | [1.88-4.48] | 21 Afro-Caribbean cases; 1,010 Afro-Caribbean controls; 50 European ancestry cases; 1,202 European ancestry controls; 62 Hispanic cases; 658 Hispanic controls | Afro-Caribbean(1031) | European(1252) | Hispanic(720) | ALL(3003) | HIS(720) | AFR(1031) | EUR(1252) | ALL(3003) | Preeclampsia | HPOID:0100602 | Preeclampsia | DOID:10591 | pre-eclampsia | D011225 | Pre-Eclampsia | NA | NA | Pre-Eclampsia |
13 | 77723410 | rs7337686 | G | A | rs7337686 | 23551011 | 6.60E-06 | EA | 2.68 | [1.74-4.11] | 21 Afro-Caribbean cases; 1,010 Afro-Caribbean controls; 50 European ancestry cases; 1,202 European ancestry controls; 62 Hispanic cases; 658 Hispanic controls | Afro-Caribbean(1031) | European(1252) | Hispanic(720) | ALL(3003) | HIS(720) | AFR(1031) | EUR(1252) | ALL(3003) | Preeclampsia | HPOID:0100602 | Preeclampsia | DOID:10591 | pre-eclampsia | D011225 | Pre-Eclampsia | NA | NA | Pre-Eclampsia |
13 | 77862984 | rs9530631 | G | A | rs9530631 | 23551011 | 5.91E-06 | EA | 2.69 | [1.75-4.12] | 21 Afro-Caribbean cases; 1,010 Afro-Caribbean controls; 50 European ancestry cases; 1,202 European ancestry controls; 62 Hispanic cases; 658 Hispanic controls | Afro-Caribbean(1031) | European(1252) | Hispanic(720) | ALL(3003) | HIS(720) | AFR(1031) | EUR(1252) | ALL(3003) | Preeclampsia | HPOID:0100602 | Preeclampsia | DOID:10591 | pre-eclampsia | D011225 | Pre-Eclampsia | NA | NA | Pre-Eclampsia |
13 | 77879376 | rs7322722 | G | A | rs7322722 | 23551011 | 1.00E-06 | EA | 2.93 | [1.90-4.52] | 21 Afro-Caribbean cases; 1,010 Afro-Caribbean controls; 50 European ancestry cases; 1,202 European ancestry controls; 62 Hispanic cases; 658 Hispanic controls | Afro-Caribbean(1031) | European(1252) | Hispanic(720) | ALL(3003) | HIS(720) | AFR(1031) | EUR(1252) | ALL(3003) | Preeclampsia | HPOID:0100602 | Preeclampsia | DOID:10591 | pre-eclampsia | D011225 | Pre-Eclampsia | NA | NA | Pre-Eclampsia |
13 | 102680126 | rs11617740 | G | A | rs11617740 | 23551011 | 7.00E-07 | Afro-Caribbean | 16.69 | [5.53-51.97] | 21 Afro-Caribbean cases; 1,010 Afro-Caribbean controls; 50 European ancestry cases; 1,202 European ancestry controls; 62 Hispanic cases; 658 Hispanic controls | Afro-Caribbean(1031) | European(1252) | Hispanic(720) | ALL(3003) | HIS(720) | AFR(1031) | EUR(1252) | ALL(3003) | Preeclampsia | HPOID:0100602 | Preeclampsia | DOID:10591 | pre-eclampsia | D011225 | Pre-Eclampsia | NA | NA | Pre-Eclampsia |
15 | 44774202 | rs2453274 | C | T | rs2453274 | 22432041 | 0.00000232 | NA | NA | NA | 538 European ancestry cases; 540 European ancestry controls | European(1078) | ALL(1078) | EUR(1078) | ALL(1078) | Preeclampsia | HPOID:0100602 | Preeclampsia | DOID:10591 | pre-eclampsia | D011225 | Pre-Eclampsia | NA | NA | Pre-Eclampsia | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | C |
16 | 76043201 | rs7199697 | A | G | rs7199697 | 23551011 | 9.59E-06 | Hispanic | 3.98 | [2.16-7.33] | 21 Afro-Caribbean cases; 1,010 Afro-Caribbean controls; 50 European ancestry cases; 1,202 European ancestry controls; 62 Hispanic cases; 658 Hispanic controls | Afro-Caribbean(1031) | European(1252) | Hispanic(720) | ALL(3003) | HIS(720) | AFR(1031) | EUR(1252) | ALL(3003) | Preeclampsia | HPOID:0100602 | Preeclampsia | DOID:10591 | pre-eclampsia | D011225 | Pre-Eclampsia | NA | NA | Pre-Eclampsia |
20 | 4215557 | rs1556832 | C | T | rs1556832 | 23551011 | 9.00E-06 | Afro-Caribbean | 4.33 | [2.27-8.27] | 21 Afro-Caribbean cases; 1,010 Afro-Caribbean controls; 50 European ancestry cases; 1,202 European ancestry controls; 62 Hispanic cases; 658 Hispanic controls | Afro-Caribbean(1031) | European(1252) | Hispanic(720) | ALL(3003) | HIS(720) | AFR(1031) | EUR(1252) | ALL(3003) | Preeclampsia | HPOID:0100602 | Preeclampsia | DOID:10591 | pre-eclampsia | D011225 | Pre-Eclampsia | NA | NA | Pre-Eclampsia |
20 | 5949534 | rs4815879 | G | A | rs4815879 | 23551011 | 2.00E-06 | Afro-Caribbean | 14.57 | [4.81-44.17] | 21 Afro-Caribbean cases; 1,010 Afro-Caribbean controls; 50 European ancestry cases; 1,202 European ancestry controls; 62 Hispanic cases; 658 Hispanic controls | Afro-Caribbean(1031) | European(1252) | Hispanic(720) | ALL(3003) | HIS(720) | AFR(1031) | EUR(1252) | ALL(3003) | Preeclampsia | HPOID:0100602 | Preeclampsia | DOID:10591 | pre-eclampsia | D011225 | Pre-Eclampsia | NA | NA | Pre-Eclampsia |
21 | 22188735 | rs2826538 | C | T | rs2826538 | 22432041 | 0.00000593 | NA | NA | NA | 538 European ancestry cases; 540 European ancestry controls | European(1078) | ALL(1078) | EUR(1078) | ALL(1078) | Preeclampsia | HPOID:0100602 | Preeclampsia | DOID:10591 | pre-eclampsia | D011225 | Pre-Eclampsia | NA | NA | Pre-Eclampsia | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | C |
21 | 36208062 | rs9976946 | C | T | rs9976946 | 23551011 | 5.00E-06 | EA | 5.5 | [2.65-11.39] | 21 Afro-Caribbean cases; 1,010 Afro-Caribbean controls; 50 European ancestry cases; 1,202 European ancestry controls; 62 Hispanic cases; 658 Hispanic controls | Afro-Caribbean(1031) | European(1252) | Hispanic(720) | ALL(3003) | HIS(720) | AFR(1031) | EUR(1252) | ALL(3003) | Preeclampsia | HPOID:0100602 | Preeclampsia | DOID:10591 | pre-eclampsia | D011225 | Pre-Eclampsia | NA | NA | Pre-Eclampsia |
21 | 43443498 | rs2839440 | C | T | rs2839440 | 23551011 | 1.00E-06 | Afro-Caribbean | 5.31 | [2.70-10.42] | 21 Afro-Caribbean cases; 1,010 Afro-Caribbean controls; 50 European ancestry cases; 1,202 European ancestry controls; 62 Hispanic cases; 658 Hispanic controls | Afro-Caribbean(1031) | European(1252) | Hispanic(720) | ALL(3003) | HIS(720) | AFR(1031) | EUR(1252) | ALL(3003) | Preeclampsia | HPOID:0100602 | Preeclampsia | DOID:10591 | pre-eclampsia | D011225 | Pre-Eclampsia | NA | NA | Pre-Eclampsia |
Mapped by lexical matching(Total Items:3) | ||||
---|---|---|---|---|
HP ID | HP Name | MP ID | MP Name | Annotation |
HP:0002910 | Elevated hepatic transaminases | MP:0002628 | hepatic steatosis | an accumulation of fat deposits in the liver |
HP:0008071 | Maternal hypertension | MP:0004217 | salt-sensitive hypertension | sustained high blood pressure that is maintained with a normal or increase in the amount of salt consumed in the diet; blood pressure may return to normotensive with a low salt diet |
HP:0001511 | Intrauterine growth retardation | MP:0011109 | lethality throughout fetal growth and development, incomplete penetrance | the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between the completion of organogenesis and birth (Mus: E14 to approximately E18.5) |
Mapped by homologous gene(Total Items:10) | ||||
---|---|---|---|---|
HP ID | HP Name | MP ID | MP Name | Annotation |
HP:0100601 | Eclampsia | MP:0006144 | increased systemic arterial systolic blood pressure | abnormal increase in the pressure in the arteries as the heart contracts and pumps blood into the arteries |
HP:0000969 | Edema | MP:0020154 | impaired humoral immune response | impaired response of the immune system that mediates secreted antibodies produced in B cells |
HP:0002910 | Elevated hepatic transaminases | MP:0020234 | decreased basal metabolism | decrease in heat production of an organism at the lowest level of cell chemistry in an inactive, awake, and fasting state |
HP:0100602 | Preeclampsia | MP:0014169 | decreased brown adipose tissue mass | decreased physical bulk or volume of brown adipose tissue |
HP:0008071 | Maternal hypertension | MP:0011442 | abnormal renal sodium ion transport | any anomaly in the directed movement of sodium ions (Na+) by the kidney |
HP:0000093 | Proteinuria | MP:0020216 | decreased circulating complement protein level | less than normal levels of the serum proteins that act sequentially to allow for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes |
HP:0001511 | Intrauterine growth retardation | MP:0020329 | decreased capillary density | reduction in the number of capillaries in a given cross-sectional area of a tissue |
HP:0001250 | Seizures | MP:3000003 | abnormal Ebner's gland morphology | any structural anomaly of the serous salivary glands which reside adjacent to the moats surrounding the circumvallate and foliate papillae just anterior to the posterior third of the tongue, anterior to the terminal sulcus; these exocrine glands secrete l |
HP:0001873 | Thrombocytopenia | MP:0020329 | decreased capillary density | reduction in the number of capillaries in a given cross-sectional area of a tissue |
HP:0000822 | Hypertension | MP:0020216 | decreased circulating complement protein level | less than normal levels of the serum proteins that act sequentially to allow for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes |
Disease ID | 182 |
---|---|
Disease | pre-eclampsia |
Case | (Waiting for update.) |