eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| post polio syndrome | ||||
| Disease ID | 563 |
|---|---|
| Disease | post polio syndrome |
| Definition | A syndrome characterized by new neuromuscular symptoms that occur at least 15 years after clinical stability has been attained in patients with a prior history of symptomatic poliomyelitis. Clinical features include new muscular weakness and atrophy of the limbs, bulbar innervated musculature, and muscles of respiration, combined with excessive fatigue, joint pain, and reduced stamina. The process is marked by slow progression and periods of stabilization. (From Ann NY Acad Sci 1995 May 25;753:68-80) |
| Synonym | muscular atrophies, post-poliomyelitis muscular atrophies, postpoliomyelitis muscular atrophy postpolio muscular atrophy, post-poliomyelitis muscular atrophy, postpoliomyelitis polio post syndrome post polio muscular atrophy post poliomyelitis muscular atrophy post poliomyelitis syndrome post poliomyelitis syndrome (disorder) post-polio progressive muscular atrophy post-polio syndrome post-polio syndromes post-poliomyelitis muscular atrophies post-poliomyelitis muscular atrophy post-poliomyelitis syndrome postpolio muscular atrophy postpolio syndrome postpolio syndrome (disorder) postpoliomyelitis muscular atrophies postpoliomyelitis muscular atrophy postpoliomyelitis syndrome postpoliomyelitis syndrome [disease/finding] ppma progressive muscular atrophy following poliomyelitis |
| Orphanet | |
| DOID | |
| ICD10 | |
| UMLS | C0080040 |
| MeSH | |
| SNOMED-CT | |
| Comorbidity | UMLS | Disease | Sentences' Count(Total Sentences:5) C0035078 | renal failure | 1 C0037317 | sleep disturbance | 1 C0037317 | sleep disturbances | 1 C0035258 | restless legs syndrome | 1 C0002736 | amyotrophic lateral sclerosis | 1 |
| Curated Gene | (Waiting for update.) |
| Inferring Gene | (Waiting for update.) |
| Text Mined Gene | Entrez_id | Symbol | Score | Resource(Total Genes:11) 55028 | C17orf80 | 5.194 | DISEASES 820 | CAMP | 2.413 | DISEASES 959 | CD40LG | 2.375 | DISEASES 2934 | GSN | 1.71 | DISEASES 23008 | KLHDC10 | 5.155 | DISEASES 4637 | MYL6 | 3.453 | DISEASES 5817 | PVR | 1.35 | DISEASES 6005 | RHAG | 2.333 | DISEASES 7124 | TNF | 2.014 | DISEASES 7415 | VCP | 2.683 | DISEASES 79971 | WLS | 2.753 | DISEASES |
| Locus | (Waiting for update.) |
| Disease ID | 563 |
|---|---|
| Disease | post polio syndrome |
| Integrated Phenotype | (Waiting for update.) |
| Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:8) HP:0012378 | Fatigue | 6 HP:0012531 | Pain | 5 HP:0007354 | Amyotrophic lateral sclerosis | 1 HP:0002015 | Swallowing difficulty | 1 HP:0000083 | Renal insufficiency | 1 HP:0001618 | Dysphonia | 1 HP:0040078 | Axonal degeneration | 1 HP:0002360 | Sleep disturbance | 1 |
| Disease ID | 563 |
|---|---|
| Disease | post polio syndrome |
| Manually Symptom | UMLS | Name(Total Manually Symptoms:1) C0026846 | muscular atrophy |
| Text Mined Symptom | UMLS | Name | Sentences' Count(Total Symptoms:4) |
Manually Genotype(Total Text Mining Genotypes:0) |
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| (Waiting for update.) |
Text Mining Genotype(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
All Snps(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Annotation(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
Mapped by lexical matching(Total Items:0) |
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| (Waiting for update.) |
Mapped by homologous gene(Total Items:0) |
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| (Waiting for update.) |
| Disease ID | 563 |
|---|---|
| Disease | post polio syndrome |
| Case | (Waiting for update.) |