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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine



   pertussis
  

Disease ID 1869
Disease pertussis
Definition
A suspension of killed Bordetella pertussis organisms, used for immunization against pertussis (WHOOPING COUGH). It is generally used in a mixture with diphtheria and tetanus toxoids (DTP). There is an acellular pertussis vaccine prepared from the purified antigenic components of Bordetella pertussis, which causes fewer adverse reactions than whole-cell vaccine and, like the whole-cell vaccine, is generally used in a mixture with diphtheria and tetanus toxoids. (From Dorland, 28th ed)
Synonym
pertussis vaccine
pertussis vaccine (product)
pertussis vaccine (substance)
pertussis vaccine [chemical/ingredient]
pertussis vaccines
vaccine, pertussis
whooping-cough vaccine
Orphanet
DOID
UMLS
C0031237
MeSH
Comorbidity
UMLS | Disease | Sentences' Count(Total Sentences:25)
C0039614  |  tetanus  |  10
C0043167  |  whooping cough  |  8
C0012546  |  diphtheria  |  6
C0006017  |  pertussis  |  3
C0032285  |  pneumonia  |  3
C0019061  |  hemolytic uremic syndrome  |  2
C0020542  |  pulmonary hypertension  |  2
C0021400  |  influenza  |  2
C0025007  |  measles  |  2
C0020538  |  hypertension  |  2
C0278883  |  metastatic melanoma  |  1
C0025202  |  melanoma  |  1
C0013990  |  emphysema  |  1
C0041296  |  tuberculosis  |  1
C0004096  |  asthma  |  1
C0032371  |  poliomyelitis  |  1
C0004626  |  bacterial pneumonia  |  1
C0019158  |  hepatitis  |  1
C0010674  |  cystic fibrosis  |  1
C0019163  |  hepatitis b  |  1
C0009443  |  coryza  |  1
C0079840  |  milk allergy  |  1
C0162429  |  undernutrition  |  1
C0004623  |  bacterial infection  |  1
C0006017  |  bordetella pertussis  |  1
Curated Gene(Waiting for update.)
Inferring Gene(Waiting for update.)
Text Mined Gene
Entrez_id | Symbol | Score | Resource(Total Genes:92)
2  |  A2M  |  1.148  |  DISEASES
65057  |  ACD  |  1.042  |  DISEASES
111  |  ADCY5  |  1.738  |  DISEASES
54936  |  ADPRHL2  |  2.957  |  DISEASES
10189  |  ALYREF  |  1.119  |  DISEASES
340075  |  ARSI  |  1.6  |  DISEASES
617  |  BCS1L  |  2.931  |  DISEASES
8911  |  CACNA1I  |  1.72  |  DISEASES
801  |  CALM1  |  4.259  |  DISEASES
930  |  CD19  |  1.589  |  DISEASES
959  |  CD40LG  |  4.032  |  DISEASES
961  |  CD47  |  1.089  |  DISEASES
974  |  CD79B  |  1.294  |  DISEASES
942  |  CD86  |  1.29  |  DISEASES
146059  |  CDAN1  |  1.074  |  DISEASES
9793  |  CKAP5  |  1.492  |  DISEASES
10202  |  DHRS2  |  1.869  |  DISEASES
1805  |  DPT  |  7.489  |  DISEASES
1850  |  DUSP8  |  1.178  |  DISEASES
23741  |  EID1  |  1.304  |  DISEASES
2029  |  ENSA  |  1.437  |  DISEASES
3266  |  ERAS  |  1.986  |  DISEASES
2079  |  ERH  |  1.362  |  DISEASES
2204  |  FCAR  |  1.039  |  DISEASES
2214  |  FCGR3A  |  1.747  |  DISEASES
2305  |  FOXM1  |  1.127  |  DISEASES
2813  |  GP2  |  1.488  |  DISEASES
29933  |  GPR132  |  1.41  |  DISEASES
23560  |  GTPBP4  |  4.872  |  DISEASES
3005  |  H1F0  |  1.052  |  DISEASES
3032  |  HADHB  |  1.027  |  DISEASES
3055  |  HCK  |  1.11  |  DISEASES
8349  |  HIST2H2BE  |  1.236  |  DISEASES
8091  |  HMGA2  |  1.515  |  DISEASES
3240  |  HP  |  1.298  |  DISEASES
3329  |  HSPD1  |  1.471  |  DISEASES
3363  |  HTR7  |  1.422  |  DISEASES
3376  |  IARS  |  1.552  |  DISEASES
3586  |  IL10  |  2.634  |  DISEASES
3605  |  IL17A  |  2.099  |  DISEASES
83737  |  ITCH  |  1.136  |  DISEASES
3684  |  ITGAM  |  2.29  |  DISEASES
3770  |  KCNJ14  |  2.258  |  DISEASES
3822  |  KLRC2  |  1.028  |  DISEASES
3980  |  LIG3  |  1.157  |  DISEASES
497634  |  LINC00293  |  3.356  |  DISEASES
4050  |  LTB  |  1.108  |  DISEASES
23542  |  MAPK8IP2  |  2.168  |  DISEASES
4155  |  MBP  |  2.786  |  DISEASES
22921  |  MSRB2  |  1.743  |  DISEASES
25821  |  MTO1  |  1.271  |  DISEASES
4625  |  MYH7  |  2.102  |  DISEASES
344022  |  NOTO  |  1.209  |  DISEASES
283869  |  NPW  |  3.219  |  DISEASES
116448  |  OLIG1  |  1.231  |  DISEASES
142  |  PARP1  |  3.719  |  DISEASES
5325  |  PLAGL1  |  2.315  |  DISEASES
5406  |  PNLIP  |  1.739  |  DISEASES
7916  |  PRRC2A  |  2.271  |  DISEASES
5888  |  RAD51  |  1.743  |  DISEASES
10411  |  RAPGEF3  |  1.461  |  DISEASES
11069  |  RAPGEF4  |  1.51  |  DISEASES
9939  |  RBM8A  |  1.081  |  DISEASES
343035  |  RD3  |  1.039  |  DISEASES
8786  |  RGS11  |  1.788  |  DISEASES
84236  |  RHBDD1  |  3.778  |  DISEASES
8780  |  RIOK3  |  2.254  |  DISEASES
6230  |  RPS25  |  2.637  |  DISEASES
29901  |  SAC3D1  |  2.959  |  DISEASES
6295  |  SAG  |  1.363  |  DISEASES
25813  |  SAMM50  |  1.685  |  DISEASES
677768  |  SCARNA13  |  2.701  |  DISEASES
404552  |  SCGB1D4  |  1.56  |  DISEASES
55315  |  SLC29A3  |  4.238  |  DISEASES
26793  |  SNORD56  |  2.505  |  DISEASES
692199  |  SNORD84  |  2.726  |  DISEASES
27286  |  SRPX2  |  2.455  |  DISEASES
6752  |  SSTR2  |  1.114  |  DISEASES
400410  |  ST20  |  2.023  |  DISEASES
8801  |  SUCLG2  |  1.644  |  DISEASES
25870  |  SUMF2  |  2.966  |  DISEASES
6863  |  TAC1  |  1.568  |  DISEASES
6892  |  TAPBP  |  2.18  |  DISEASES
7099  |  TLR4  |  3.339  |  DISEASES
7124  |  TNF  |  2.662  |  DISEASES
9760  |  TOX  |  2.579  |  DISEASES
9652  |  TTC37  |  1.167  |  DISEASES
8725  |  URI1  |  1.092  |  DISEASES
7432  |  VIP  |  1.869  |  DISEASES
23038  |  WDTC1  |  5.523  |  DISEASES
9189  |  ZBED1  |  1.476  |  DISEASES
100287226  |  ZNF729  |  3.923  |  DISEASES
Locus(Waiting for update.)
Disease ID 1869
Disease pertussis
Integrated Phenotype(Waiting for update.)
Text Mined Phenotype
HPO | Name | Sentences' Count(Total Phenotypes:20)
HP:0012735  |  Coughing  |  29
HP:0002090  |  Pneumonia  |  2
HP:0002099  |  Asthma  |  2
HP:0005575  |  Hemolytic-uremic syndrome  |  2
HP:0011947  |  Respiratory infection  |  2
HP:0002104  |  Absence of spontaneous respiration  |  2
HP:0001250  |  Seizures  |  1
HP:0002861  |  Melanoma  |  1
HP:0000961  |  Cyanosis  |  1
HP:0030828  |  Wheezing  |  1
HP:0000822  |  Hypertension  |  1
HP:0011096  |  Demyelination  |  1
HP:0001974  |  Leukocytosis  |  1
HP:0100327  |  Cow milk allergy  |  1
HP:0002013  |  Emesis  |  1
HP:0012115  |  Liver inflammation  |  1
HP:0009733  |  Glioma  |  1
HP:0002097  |  Pulmonary emphysema  |  1
HP:0002092  |  Pulmonary artery hypertension  |  1
HP:0100845  |  Anaphylactic shock  |  1
Disease ID 1869
Disease pertussis
Manually Symptom
UMLS  | Name(Total Manually Symptoms:19)
C2712323  |  hypoglycaemia
C2712322  |  tachycardia
C2707258  |  infections
C1963220  |  pulmonary hypertension
C1963101  |  encephalopathy
C1961131  |  cough
C0851887  |  adenoviral infection
C0850803  |  anaphylaxis
C0796095  |  c syndrome
C0038826  |  superinfection
C0036572  |  seizures
C0032319  |  pneumopericardium
C0027765  |  neurological disorders
C0024282  |  lymphocytosis
C0020456  |  hyperglycemia
C0019080  |  hemorrhage
C0018991  |  hemiplegia
C0014038  |  encephalitis
C0006267  |  bronchiectasis
Text Mined Symptom
UMLS | Name | Sentences' Count(Total Symptoms:5)
C0010200  |  cough  |  29
C0021311  |  infections  |  6
C0796095  |  c syndrome  |  2
C0020542  |  pulmonary hypertension  |  1
C0036572  |  seizures  |  1
Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)
Text Mining Genotype(Total Genotypes:0)
(Waiting for update.)
All Snps(Total Genotypes:0)
(Waiting for update.)
GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)
GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)
Mapped by lexical matching(Total Items:0)
(Waiting for update.)
Mapped by homologous gene(Total Items:0)
(Waiting for update.)
Disease ID 1869
Disease pertussis
Case(Waiting for update.)