eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| pemphigus foliaceus | ||||
| Disease ID | 965 |
|---|---|
| Disease | pemphigus foliaceus |
| Definition | Pemphigus foliaceus is an autoimmune blistering disease of the skin with characteristic lesions that are scaly, crusted erosions, often on an erythematous base.[1] Mucosal involvement is absent even with widespread disease.[2] - Wikipedia Reference: https://en.wikipedia.org/wiki/pemphigus foliaceus |
| Synonym | foliaceus, pemphigus pemphigus foliaceous pemphigus foliaceus (disorder) pemphigus, foliaceus pf - pemphigus foliaceous |
| Orphanet | |
| ICD10 | |
| UMLS | C0263313 |
| SNOMED-CT | |
| Comorbidity | UMLS | Disease | Sentences' Count(Total Sentences:19) C0030807 | pemphigus | 3 C0033860 | psoriasis | 2 C0040100 | thymoma | 2 C0030805 | pemphigoid | 1 C0684249 | lung carcinoma | 1 C0600139 | carcinoma of prostate | 1 C0001418 | adenocarcinoma | 1 C0007112 | adenocarcinoma of prostate | 1 C0032285 | pneumonia | 1 C0027873 | neuromyelitis optica | 1 C0037274 | dermatosis | 1 C0023418 | leukemia | 1 C0005586 | bipolar disorder | 1 C1527407 | eosinophilic pneumonia | 1 C0030805 | bullous pemphigoid | 1 C0023470 | myeloid leukemia | 1 C0030809 | pemphigus vulgaris | 1 C0023473 | chronic myeloid leukemia | 1 C0409974 | lupus erythematosus | 1 |
| Curated Gene | (Waiting for update.) |
| Inferring Gene | Entrez_id | Symbol | Resource(Total Genes:5) |
| Text Mined Gene | (Waiting for update.) |
| Locus | (Waiting for update.) |
| Disease ID | 965 |
|---|---|
| Disease | pemphigus foliaceus |
| Integrated Phenotype | HPO | Name(Total Integrated Phenotypes:6) HP:0010783 | Erythema HP:0100792 | Acantholysis HP:0200037 | Skin vesicle HP:0200041 | Skin erosion HP:0008066 | Abnormal blistering of the skin HP:0007473 | Crusting erythematous dermatitis |
| Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:10) HP:0003765 | Psoriasis | 2 HP:0100522 | Thymoma | 2 HP:0001909 | Leukemia | 1 HP:0007302 | Bipolar disorder | 1 HP:0002090 | Pneumonia | 1 HP:0012324 | Myeloid leukemia | 1 HP:0005506 | Chronic myeloid leukemia | 1 HP:0001019 | Exfoliative dermititis | 1 HP:0100792 | Acantholysis | 1 HP:0030731 | Carcinoma | 1 |
| Disease ID | 965 |
|---|---|
| Disease | pemphigus foliaceus |
| Manually Symptom | UMLS | Name(Total Manually Symptoms:11) C2697391 | rheumatoid arthritis C0302424 | generalized vaccinia C0265970 | disseminated superficial actinic porokeratosis C0263325 | transient acantholytic dermatosis C0235025 | motor peripheral neuropathy C0038463 | strongyloidiasis C0037284 | skin lesions C0030809 | pemphigus vulgaris C0022504 | kaposi's varicelliform eruption C0020676 | thyroid insufficiency C0013595 | eczema |
| Text Mined Symptom | UMLS | Name | Sentences' Count(Total Symptoms:2) |
Manually Genotype(Total Text Mining Genotypes:0) |
|---|
| (Waiting for update.) |
Text Mining Genotype(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
All Snps(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Annotation(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
Mapped by lexical matching(Total Items:1) | ||||
|---|---|---|---|---|
| HP ID | HP Name | MP ID | MP Name | Annotation |
| HP:0008066 | Abnormal blistering of the skin | MP:0009536 | abnormal interstitial cell of Cajal morphology | any structural anomaly in the type of cell found in the gastrointestinal tract and serving as a pacemaker that triggers gut contraction; ICCs mediate inputs from the enteric nervous system to smooth muscle cells and are thought to be the cells from which |
Mapped by homologous gene(Total Items:6) | ||||
|---|---|---|---|---|
| HP ID | HP Name | MP ID | MP Name | Annotation |
| HP:0007473 | Crusting erythematous dermatitis | MP:0020254 | decreased collagen level | decreased level of the main structural protein of the various connective tissues in animals |
| HP:0100792 | Acantholysis | MP:0013278 | decreased fasted circulating glucose level | reduction in the amount of glucose in the blood at some defined time point after eating compared to controls |
| HP:0010783 | Erythema | MP:0013781 | abnormal mammary gland luminal epithelium morphology | any structural anomaly of the inner cell layer of the mammary epithelium bilayer that lines the luminal surface of mammary gland ducts and alveoli; luminal cells have only limited contact with the underlying basement membrane and surrounding connective ti |
| HP:0200041 | Skin erosion | MP:0020137 | decreased bone mineralization | decrease in the rate at which minerals are deposited into bone |
| HP:0008066 | Abnormal blistering of the skin | MP:0020039 | increased bone ossification | increase in the formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance |
| HP:0200037 | Skin vesicle | MP:0011094 | embryonic lethality before implantation, complete penetrance | death of all organisms of a given genotype in a population between fertilization and implantation (Mus: E0 to less than E4.5) |
| Disease ID | 965 |
|---|---|
| Disease | pemphigus foliaceus |
| Case | (Waiting for update.) |