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	neutropenia

Disease ID	588
Disease	neutropenia
Definition	A decrease in the number of LEUKOCYTES in a blood sample below the normal range (LEUKOCYTE COUNT less than 4000).
Synonym	decreased blood leukocyte number leucocytopenia leucopenia leucopenia (disorder) leucopenia (finding) leucopenia, nos leukocytopenia leukocytopenia nos leukocytopenia, unspecified leukocytopenias leukopenia leukopenia (disorder) leukopenia [disease/finding] leukopenia nos leukopenia, nos leukopenias
DOID	DOID:615 DOID:1227
UMLS	C0023530
MeSH	D007970 D009503
SNOMED-CT	SNOMEDCT_US_2016_09_01:84828003
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:176) C0002871 \| anemia \| 21 C0040034 \| thrombocytopenia \| 20 C0023530 \| leukopenia \| 16 C0006142 \| breast cancer \| 16 C0024312 \| lymphopenia \| 12 C0027947 \| neutropenia \| 10 C0032285 \| pneumonia \| 10 C0023418 \| leukemia \| 10 C0026946 \| fungal infection \| 10 C0024299 \| lymphoma \| 9 C0004623 \| bacterial infection \| 9 C0026946 \| fungal infections \| 8 C0376545 \| hematological malignancies \| 8 C0242379 \| lung cancer \| 8 C0019158 \| hepatitis \| 7 C0023530 \| leucopenia \| 7 C0376545 \| hematologic malignancies \| 7 C0020532 \| hypersplenism \| 7 C0004030 \| aspergillosis \| 6 C0085669 \| acute leukemia \| 6 C0004623 \| bacterial infections \| 5 C0009402 \| colorectal cancer \| 5 C0002878 \| hemolytic anemia \| 5 C0023470 \| myeloid leukemia \| 5 C0023467 \| acute myeloid leukemia \| 5 C0019196 \| hepatitis c \| 5 C0007113 \| rectal cancer \| 5 C0020538 \| hypertension \| 5 C0015230 \| rash \| 4 C0026764 \| multiple myeloma \| 4 C0003873 \| rheumatoid arthritis \| 4 C0376545 \| hematologic malignancy \| 4 C0376545 \| hematological malignancy \| 4 C0024141 \| systemic lupus erythematosus \| 4 C0409974 \| lupus erythematosus \| 4 C0026848 \| myopathy \| 4 C0003864 \| arthritis \| 4 C0007131 \| non-small cell lung cancer \| 3 C0011991 \| diarrhoea \| 3 C0024305 \| non-hodgkin's lymphoma \| 3 C0024305 \| non-hodgkin lymphoma \| 3 C0019829 \| hodgkin lymphoma \| 3 C0019829 \| hodgkin's lymphoma \| 3 C0030312 \| pancytopenia \| 3 C0149925 \| small cell lung cancer \| 3 C0026764 \| myeloma \| 3 C0026718 \| mucormycosis \| 3 C0001824 \| granulocytopenia \| 3 C0007642 \| cellulitis \| 3 C0002871 \| anaemia \| 3 C0442874 \| neuropathy \| 2 C0021400 \| influenza \| 2 C1140680 \| ovarian cancer \| 2 C0011847 \| diabetes \| 2 C0020455 \| hypergammaglobulinemia \| 2 C0175709 \| centronuclear myopathy \| 2 C1261473 \| soft tissue sarcoma \| 2 C0021390 \| inflammatory bowel disease \| 2 C0038362 \| stomatitis \| 2 C0085110 \| severe combined immunodeficiency \| 2 C0270612 \| leukoencephalopathy \| 2 C0235974 \| pancreatic cancer \| 2 C0002726 \| amyloidosis \| 2 C0023890 \| cirrhosis \| 2 C0751651 \| mitochondrial disease \| 2 C0878544 \| cardiomyopathy \| 2 C0272170 \| shwachman-diamond syndrome \| 2 C0574083 \| barth syndrome \| 2 C1522378 \| large granular lymphocytosis \| 2 C1140680 \| ovarian ca \| 2 C0042384 \| vasculitis \| 2 C0021831 \| bowel disease \| 2 C0085110 \| severe combined immunodefic \| 2 C0006840 \| candidiasis \| 2 C0023418 \| leukaemia \| 2 C0026986 \| myelodysplastic syndrome \| 2 C0031069 \| familial mediterranean fever \| 2 C0011991 \| diarrhea \| 2 C0007134 \| renal cell carcinoma \| 1 C0879615 \| stromal tumor \| 1 C0600327 \| toxic shock syndrome \| 1 C0002874 \| aplastic anemia \| 1 C0023890 \| liver cirrhosis \| 1 C0339962 \| pulmonary mucormycosis \| 1 C0020542 \| pulmonary hypertension \| 1 C0030305 \| pancreatitis \| 1 C1257843 \| pseudomembranous colitis \| 1 C0282193 \| iron overload \| 1 C0002170 \| alopecia \| 1 C0003615 \| appendicitis \| 1 C0035435 \| rheumatic diseases \| 1 C0155862 \| pneumococcal pneumonia \| 1 C0007193 \| dilated cardiomyopathy \| 1 C0024623 \| stomach cancer \| 1 C0007102 \| colon cancer \| 1 C0948303 \| peritoneal carcinoma \| 1 C0014742 \| erythema multiforme \| 1 C0017574 \| gingivitis \| 1 C0011849 \| diabetes mellitus \| 1 C0836924 \| thrombocytosis \| 1 C0001824 \| agranulocytosis \| 1 C0014761 \| hemolytic disease of the newborn \| 1 C0015773 \| felty syndrome \| 1 C0014121 \| infective endocarditis \| 1 C0010692 \| cystitis \| 1 C0024530 \| malaria \| 1 C0033975 \| psychosis \| 1 C0002886 \| macrocytic anemia \| 1 C0241910 \| autoimmune hepatitis \| 1 C0029443 \| osteomyelitis \| 1 C0034150 \| purpura \| 1 C0042164 \| uveitis \| 1 C0023467 \| acute myeloid leukaemia \| 1 C0023448 \| lymphocytic leukemia \| 1 C0751651 \| mitochondrial diseases \| 1 C0031347 \| pharyngeal cancer \| 1 C0021053 \| immune disease \| 1 C0023443 \| hairy-cell leukemia \| 1 C0031099 \| periodontitis \| 1 C0023530 \| leukocytopenia \| 1 C0751606 \| adult acute lymphoblastic leukemia \| 1 C0004626 \| bacterial pneumonia \| 1 C1522378 \| large granular lymphocytic leukemia \| 1 C0019655 \| histoplasmosis \| 1 C0085652 \| pyoderma gangrenosum \| 1 C0026691 \| kawasaki syndrome \| 1 C0019204 \| hepatocellular carcinoma \| 1 C0024312 \| lymphocytopenia \| 1 C0020541 \| portal hypertension \| 1 C0023449 \| acute lymphoblastic leukaemia \| 1 C0085669 \| acute leukaemia \| 1 C0268132 \| dpd deficiency \| 1 C0032285 \| pneumoniae \| 1 C1955861 \| t-lgl leukemia \| 1 C0041466 \| typhoid fever \| 1 C0032914 \| preeclampsia \| 1 C0023470 \| myeloid leukaemia \| 1 C0268124 \| ada deficiency \| 1 C1136085 \| monoclonal gammopathy \| 1 C0023467 \| acute myelogenous leukemia \| 1 C0023075 \| laryngeal stenosis \| 1 C0238198 \| gastrointestinal stromal tumor \| 1 C0026985 \| myelodysplasia \| 1 C0011570 \| depression \| 1 C0023895 \| liver disease \| 1 C0007131 \| nsclc \| 1 C0011854 \| type 1 diabetes mellitus \| 1 C0020456 \| hyperglycemia \| 1 C0153392 \| nasopharyngeal cancer \| 1 C0023448 \| lymphoblastic leukemia \| 1 C0011854 \| type 1 diabetes \| 1 C0023524 \| progressive multifocal leukoencephalopathy \| 1 C0276758 \| fusarium infection \| 1 C0035309 \| retinopathy \| 1 C0034212 \| pyoderma \| 1 C0041228 \| african trypanosomiasis \| 1 C0014868 \| esophagitis \| 1 C0014236 \| endophthalmitis \| 1 C0006060 \| boutonneuse fever \| 1 C0007570 \| celiac disease \| 1 C0023449 \| acute lymphoblastic leukemia \| 1 C0036341 \| schizophrenia \| 1 C0041466 \| typhoid \| 1 C0405580 \| hypoadrenocorticism \| 1 C0023467 \| acute myeloblastic leukemia \| 1 C0278689 \| recurrent ovarian cancer \| 1 C0024291 \| hemophagocytic syndrome \| 1 C0162670 \| mitochondrial myopathy \| 1 C0023452 \| childhood acute lymphoblastic leukemia \| 1 C0015773 \| felty's syndrome \| 1 C0031154 \| peritonitis \| 1 C0009319 \| colitis \| 1 C0002896 \| sideroblastic anemia \| 1 C0032310 \| viral pneumonia \| 1 C0023467 \| acute myelogenous leukemia (aml) \| 1 C0035435 \| rheumatic disease \| 1
Curated Gene	Entrez_id \| Symbol \| Resource(Total Genes:21) 5243 \| ABCB1 \| CTD_human 3553 \| IL1B \| CTD_human 1440 \| CSF3 \| CTD_human 4524 \| MTHFR \| CTD_human 3440 \| IFNA2 \| CTD_human 3558 \| IL2 \| CTD_human 7454 \| WAS \| GHR 1806 \| DPYD \| CTD_human 54658 \| UGT1A1 \| CTD_human 1437 \| CSF2 \| CTD_human 3562 \| IL3 \| CTD_human 10456 \| HAX1 \| GHR 2213 \| FCGR2B \| CTD_human 10 \| NAT2 \| CTD_human 84522 \| JAGN1 \| CTD_human 2672 \| GFI1 \| GHR 1991 \| ELANE \| CTD_human;GHR 8797 \| TNFRSF10A \| CTD_human 7172 \| TPMT \| CTD_human 92579 \| G6PC3 \| GHR 374569 \| ASPG \| CTD_human
Inferring Gene	Entrez_id \| Symbol \| Resource(Total Genes:36) 80216 \| ALPK1 \| CIPHER 79648 \| MCPH1 \| CIPHER 5243 \| ABCB1 \| CIPHER;CTD_human 9429 \| ABCG2 \| CIPHER 1441 \| CSF3R \| CIPHER 1576 \| CYP3A4 \| CIPHER 1577 \| CYP3A5 \| CIPHER 2067 \| ERCC1 \| CIPHER 2068 \| ERCC2 \| CIPHER 2944 \| GSTM1 \| CIPHER 2950 \| GSTP1 \| CIPHER 2952 \| GSTT1 \| CIPHER 3553 \| IL1B \| CIPHER;CTD_human 3557 \| IL1RN \| CIPHER 3569 \| IL6 \| CIPHER 4524 \| MTHFR \| CIPHER;CTD_human 4548 \| MTR \| CIPHER 7124 \| TNF \| CIPHER 7298 \| TYMS \| CIPHER 54658 \| UGT1A1 \| CIPHER;CTD_human 7372 \| UMPS \| CIPHER 7507 \| XPA \| CIPHER 7515 \| XRCC1 \| CIPHER 3440 \| IFNA2 \| CTD_human 1806 \| DPYD \| CTD_human 84522 \| JAGN1 \| CTD_human 3562 \| IL3 \| CTD_human 3558 \| IL2 \| CTD_human 7172 \| TPMT \| CTD_human 8797 \| TNFRSF10A \| CTD_human 374569 \| ASPG \| CTD_human 1437 \| CSF2 \| CTD_human 1991 \| ELANE \| CTD_human 10 \| NAT2 \| CTD_human 1440 \| CSF3 \| CTD_human 2213 \| FCGR2B \| CTD_human
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:569) 4363 \| ABCC1 \| 2.414 \| DISEASES 4363 \| ABCC1 \| 2.268 \| DISEASES 85320 \| ABCC11 \| 1.258 \| DISEASES 1244 \| ABCC2 \| 3.418 \| DISEASES 1244 \| ABCC2 \| 3.312 \| DISEASES 10257 \| ABCC4 \| 2.189 \| DISEASES 10257 \| ABCC4 \| 1.973 \| DISEASES 10057 \| ABCC5 \| 1.493 \| DISEASES 10057 \| ABCC5 \| 1.232 \| DISEASES 25 \| ABL1 \| 1.828 \| DISEASES 25 \| ABL1 \| 1.226 \| DISEASES 65057 \| ACD \| 2.02 \| DISEASES 65057 \| ACD \| 1.99 \| DISEASES 100 \| ADA \| 2.696 \| DISEASES 100 \| ADA \| 1.015 \| DISEASES 199800 \| ADM5 \| 1.019 \| DISEASES 64782 \| AEN \| 1.403 \| DISEASES 4299 \| AFF1 \| 1.073 \| DISEASES 4299 \| AFF1 \| 1.03 \| DISEASES 2334 \| AFF2 \| 1.07 \| DISEASES 174 \| AFP \| 1.806 \| DISEASES 204 \| AK2 \| 2.836 \| DISEASES 204 \| AK2 \| 2.575 \| DISEASES 1645 \| AKR1C1 \| 1.77 \| DISEASES 1645 \| AKR1C1 \| 1.694 \| DISEASES 238 \| ALK \| 2.318 \| DISEASES 238 \| ALK \| 2.157 \| DISEASES 257 \| ALX3 \| 2.69 \| DISEASES 257 \| ALX3 \| 2.558 \| DISEASES 23294 \| ANKS1A \| 1.573 \| DISEASES 23294 \| ANKS1A \| 1.312 \| DISEASES 316 \| AOX1 \| 1.931 \| DISEASES 316 \| AOX1 \| 1.671 \| DISEASES 84071 \| ARMC2 \| 1.483 \| DISEASES 84071 \| ARMC2 \| 1.222 \| DISEASES 171023 \| ASXL1 \| 1.486 \| DISEASES 171023 \| ASXL1 \| 1.287 \| DISEASES 155066 \| ATP6V0E2 \| 1.934 \| DISEASES 9212 \| AURKB \| 2.956 \| DISEASES 9212 \| AURKB \| 2.839 \| DISEASES 158835 \| AWAT2 \| 1.041 \| DISEASES 567 \| B2M \| 3.441 \| DISEASES 567 \| B2M \| 2.76 \| DISEASES 2683 \| B4GALT1 \| 2.341 \| DISEASES 2683 \| B4GALT1 \| 2.08 \| DISEASES 9334 \| B4GALT5 \| 1.071 \| DISEASES 10018 \| BCL2L11 \| 1.487 \| DISEASES 631 \| BFSP1 \| 1.181 \| DISEASES 672 \| BRCA1 \| 1.506 \| DISEASES 672 \| BRCA1 \| 1.312 \| DISEASES 685 \| BTC \| 2.074 \| DISEASES 685 \| BTC \| 1.813 \| DISEASES 28970 \| C11orf54 \| 1.503 \| DISEASES 51161 \| C3orf18 \| 1.034 \| DISEASES 720 \| C4A \| 1.576 \| DISEASES 728 \| C5AR1 \| 1.525 \| DISEASES 728 \| C5AR1 \| 1.233 \| DISEASES 65250 \| C5orf42 \| 3.641 \| DISEASES 65250 \| C5orf42 \| 3.571 \| DISEASES 116328 \| C8orf34 \| 2.216 \| DISEASES 116328 \| C8orf34 \| 1.955 \| DISEASES 778 \| CACNA1F \| 1.024 \| DISEASES 93589 \| CACNA2D4 \| 1.883 \| DISEASES 285782 \| CAGE1 \| 2.401 \| DISEASES 285782 \| CAGE1 \| 2.233 \| DISEASES 799 \| CALCR \| 1.145 \| DISEASES 820 \| CAMP \| 1.787 \| DISEASES 820 \| CAMP \| 1.687 \| DISEASES 64170 \| CARD9 \| 2.259 \| DISEASES 64170 \| CARD9 \| 2.207 \| DISEASES 841 \| CASP8 \| 1.663 \| DISEASES 57126 \| CD177 \| 4.582 \| DISEASES 57126 \| CD177 \| 4.406 \| DISEASES 653579 \| CD177P1 \| 2.643 \| DISEASES 653579 \| CD177P1 \| 2.382 \| DISEASES 930 \| CD19 \| 4.401 \| DISEASES 930 \| CD19 \| 2.879 \| DISEASES 911 \| CD1C \| 1.303 \| DISEASES 914 \| CD2 \| 3.608 \| DISEASES 914 \| CD2 \| 2.693 \| DISEASES 951 \| CD37 \| 1.24 \| DISEASES 917 \| CD3G \| 2.01 \| DISEASES 958 \| CD40 \| 2.109 \| DISEASES 958 \| CD40 \| 1.646 \| DISEASES 959 \| CD40LG \| 5.121 \| DISEASES 959 \| CD40LG \| 3.886 \| DISEASES 960 \| CD44 \| 2.675 \| DISEASES 962 \| CD48 \| 1.181 \| DISEASES 921 \| CD5 \| 3.315 \| DISEASES 921 \| CD5 \| 2.391 \| DISEASES 1043 \| CD52 \| 4.143 \| DISEASES 1043 \| CD52 \| 2.997 \| DISEASES 966 \| CD59 \| 1.902 \| DISEASES 966 \| CD59 \| 1.408 \| DISEASES 923 \| CD6 \| 1.345 \| DISEASES 923 \| CD6 \| 1.046 \| DISEASES 942 \| CD86 \| 1.328 \| DISEASES 926 \| CD8B \| 1.08 \| DISEASES 978 \| CDA \| 2.682 \| DISEASES 978 \| CDA \| 2.464 \| DISEASES 988 \| CDC5L \| 1.148 \| DISEASES 1025 \| CDK9 \| 1.962 \| DISEASES 1025 \| CDK9 \| 1.953 \| DISEASES 1029 \| CDKN2A \| 1.365 \| DISEASES 1029 \| CDKN2A \| 1.15 \| DISEASES 1041 \| CDSN \| 2.602 \| DISEASES 1050 \| CEBPA \| 2.333 \| DISEASES 1050 \| CEBPA \| 2.249 \| DISEASES 3075 \| CFH \| 1.851 \| DISEASES 3075 \| CFH \| 1.462 \| DISEASES 55636 \| CHD7 \| 1.629 \| DISEASES 1111 \| CHEK1 \| 2.146 \| DISEASES 1111 \| CHEK1 \| 1.886 \| DISEASES 1154 \| CISH \| 1.036 \| DISEASES 1154 \| CISH \| 1.024 \| DISEASES 1192 \| CLIC1 \| 3.328 \| DISEASES 1192 \| CLIC1 \| 3.068 \| DISEASES 51287 \| COA4 \| 2.195 \| DISEASES 51287 \| COA4 \| 1.934 \| DISEASES 80781 \| COL18A1 \| 1.664 \| DISEASES 80781 \| COL18A1 \| 1.365 \| DISEASES 1369 \| CPN1 \| 1.301 \| DISEASES 1369 \| CPN1 \| 1.04 \| DISEASES 1378 \| CR1 \| 2.593 \| DISEASES 1378 \| CR1 \| 2.39 \| DISEASES 1380 \| CR2 \| 3.025 \| DISEASES 1380 \| CR2 \| 2.127 \| DISEASES 1435 \| CSF1 \| 2.869 \| DISEASES 1435 \| CSF1 \| 2.796 \| DISEASES 1438 \| CSF2RA \| 1.64 \| DISEASES 1438 \| CSF2RA \| 1.379 \| DISEASES 1441 \| CSF3R \| 5.709 \| DISEASES 1441 \| CSF3R \| 5.461 \| DISEASES 728090 \| CT47A2 \| 1.192 \| DISEASES 10106 \| CTDSP2 \| 1.23 \| DISEASES 11330 \| CTRC \| 1.49 \| DISEASES 11330 \| CTRC \| 1.23 \| DISEASES 6387 \| CXCL12 \| 2.457 \| DISEASES 6387 \| CXCL12 \| 2.058 \| DISEASES 7852 \| CXCR4 \| 2.978 \| DISEASES 7852 \| CXCR4 \| 2.735 \| DISEASES 1544 \| CYP1A2 \| 1.84 \| DISEASES 1544 \| CYP1A2 \| 1.041 \| DISEASES 1555 \| CYP2B6 \| 1.082 \| DISEASES 1557 \| CYP2C19 \| 2.278 \| DISEASES 1557 \| CYP2C19 \| 2.142 \| DISEASES 1558 \| CYP2C8 \| 2.837 \| DISEASES 1558 \| CYP2C8 \| 2.217 \| DISEASES 1565 \| CYP2D6 \| 1.145 \| DISEASES 1576 \| CYP3A4 \| 3.929 \| DISEASES 1576 \| CYP3A4 \| 3.813 \| DISEASES 199699 \| DAND5 \| 1.59 \| DISEASES 199699 \| DAND5 \| 1.564 \| DISEASES 8816 \| DCAF5 \| 1.533 \| DISEASES 8816 \| DCAF5 \| 1.273 \| DISEASES 64421 \| DCLRE1C \| 1.834 \| DISEASES 1635 \| DCTD \| 2.336 \| DISEASES 1635 \| DCTD \| 2.076 \| DISEASES 51428 \| DDX41 \| 1.819 \| DISEASES 1719 \| DHFR \| 2.078 \| DISEASES 1719 \| DHFR \| 1.711 \| DISEASES 28514 \| DLL1 \| 3.99 \| DISEASES 28514 \| DLL1 \| 3.817 \| DISEASES 3301 \| DNAJA1 \| 2.487 \| DISEASES 3301 \| DNAJA1 \| 2.226 \| DISEASES 55735 \| DNAJC11 \| 1.274 \| DISEASES 1785 \| DNM2 \| 1.152 \| DISEASES 1785 \| DNM2 \| 1.111 \| DISEASES 1791 \| DNTT \| 1.733 \| DISEASES 81704 \| DOCK8 \| 2.877 \| DISEASES 1806 \| DPYD \| 3.799 \| DISEASES 1806 \| DPYD \| 3.797 \| DISEASES 1825 \| DSC3 \| 1.374 \| DISEASES 1825 \| DSC3 \| 1.114 \| DISEASES 5169 \| ENPP3 \| 1.409 \| DISEASES 5169 \| ENPP3 \| 1.398 \| DISEASES 57634 \| EP400 \| 1.395 \| DISEASES 57634 \| EP400 \| 1.134 \| DISEASES 2068 \| ERCC2 \| 1.406 \| DISEASES 2068 \| ERCC2 \| 1.359 \| DISEASES 30816 \| ERVW-1 \| 1.537 \| DISEASES 51466 \| EVL \| 1.369 \| DISEASES 51466 \| EVL \| 1.247 \| DISEASES 2152 \| F3 \| 3.328 \| DISEASES 2152 \| F3 \| 1.882 \| DISEASES 54942 \| FAM206A \| 1.131 \| DISEASES 56975 \| FAM20C \| 1.701 \| DISEASES 55120 \| FANCL \| 1.493 \| DISEASES 55120 \| FANCL \| 1.233 \| DISEASES 2193 \| FARSA \| 1.219 \| DISEASES 355 \| FAS \| 3.275 \| DISEASES 356 \| FASLG \| 3.04 \| DISEASES 356 \| FASLG \| 1.867 \| DISEASES 2209 \| FCGR1A \| 2.537 \| DISEASES 2209 \| FCGR1A \| 2.282 \| DISEASES 2213 \| FCGR2B \| 1.465 \| DISEASES 2213 \| FCGR2B \| 1.328 \| DISEASES 2214 \| FCGR3A \| 4.63 \| DISEASES 2214 \| FCGR3A \| 4.217 \| DISEASES 2219 \| FCN1 \| 1.235 \| DISEASES 2323 \| FLT3LG \| 1.827 \| DISEASES 2323 \| FLT3LG \| 1.289 \| DISEASES 2329 \| FMO4 \| 1.153 \| DISEASES 50943 \| FOXP3 \| 3.21 \| DISEASES 2526 \| FUT4 \| 2.828 \| DISEASES 2526 \| FUT4 \| 2.588 \| DISEASES 53827 \| FXYD5 \| 1.974 \| DISEASES 53827 \| FXYD5 \| 1.908 \| DISEASES 2534 \| FYN \| 1.422 \| DISEASES 2624 \| GATA2 \| 2.752 \| DISEASES 2624 \| GATA2 \| 1.515 \| DISEASES 2628 \| GATM \| 2.408 \| DISEASES 2628 \| GATM \| 2.31 \| DISEASES 8328 \| GFI1B \| 2.715 \| DISEASES 8328 \| GFI1B \| 2.667 \| DISEASES 728441 \| GGT2 \| 2.054 \| DISEASES 728441 \| GGT2 \| 1.207 \| DISEASES 55340 \| GIMAP5 \| 4.415 \| DISEASES 474344 \| GIMAP6 \| 1.217 \| DISEASES 2804 \| GOLGB1 \| 2.629 \| DISEASES 2804 \| GOLGB1 \| 2.51 \| DISEASES 2805 \| GOT1 \| 1.422 \| DISEASES 2805 \| GOT1 \| 1.137 \| DISEASES 2885 \| GRB2 \| 2.347 \| DISEASES 2885 \| GRB2 \| 2.033 \| DISEASES 2938 \| GSTA1 \| 1.135 \| DISEASES 2938 \| GSTA1 \| 1.006 \| DISEASES 2950 \| GSTP1 \| 2.437 \| DISEASES 2950 \| GSTP1 \| 2.423 \| DISEASES 2994 \| GYPB \| 2.207 \| DISEASES 2994 \| GYPB \| 1.947 \| DISEASES 3014 \| H2AFX \| 1.01 \| DISEASES 3035 \| HARS \| 1.16 \| DISEASES 10456 \| HAX1 \| 5.496 \| DISEASES 10456 \| HAX1 \| 5.235 \| DISEASES 3039 \| HBA1 \| 1.508 \| DISEASES 3043 \| HBB \| 2.255 \| DISEASES 3043 \| HBB \| 1.941 \| DISEASES 3055 \| HCK \| 2.588 \| DISEASES 3055 \| HCK \| 2.361 \| DISEASES 9734 \| HDAC9 \| 1.39 \| DISEASES 284004 \| HEXDC \| 2.019 \| DISEASES 284004 \| HEXDC \| 1.758 \| DISEASES 51155 \| HN1 \| 4.282 \| DISEASES 51155 \| HN1 \| 4.219 \| DISEASES 3205 \| HOXA9 \| 1.011 \| DISEASES 3240 \| HP \| 2.503 \| DISEASES 3240 \| HP \| 1.448 \| DISEASES 3274 \| HRH2 \| 1.846 \| DISEASES 3274 \| HRH2 \| 1.621 \| DISEASES 3359 \| HTR3A \| 2.736 \| DISEASES 3359 \| HTR3A \| 2.72 \| DISEASES 3363 \| HTR7 \| 1.225 \| DISEASES 3451 \| IFNA17 \| 1.898 \| DISEASES 3451 \| IFNA17 \| 1.554 \| DISEASES 3440 \| IFNA2 \| 4.423 \| DISEASES 3440 \| IFNA2 \| 3.59 \| DISEASES 3456 \| IFNB1 \| 3.38 \| DISEASES 3456 \| IFNB1 \| 1.067 \| DISEASES 3481 \| IGF2 \| 1.027 \| DISEASES 3486 \| IGFBP3 \| 1.235 \| DISEASES 3486 \| IGFBP3 \| 1.204 \| DISEASES 3586 \| IL10 \| 3.299 \| DISEASES 3586 \| IL10 \| 1.83 \| DISEASES 3605 \| IL17A \| 2.221 \| DISEASES 3605 \| IL17A \| 1.479 \| DISEASES 23765 \| IL17RA \| 1.036 \| DISEASES 3559 \| IL2RA \| 2.41 \| DISEASES 3561 \| IL2RG \| 2.993 \| DISEASES 3563 \| IL3RA \| 1.806 \| DISEASES 3614 \| IMPDH1 \| 1.953 \| DISEASES 3614 \| IMPDH1 \| 1.484 \| DISEASES 3615 \| IMPDH2 \| 2.344 \| DISEASES 3615 \| IMPDH2 \| 1.662 \| DISEASES 54556 \| ING3 \| 3.373 \| DISEASES 54556 \| ING3 \| 2.966 \| DISEASES 3676 \| ITGA4 \| 1.182 \| DISEASES 3683 \| ITGAL \| 3.354 \| DISEASES 3683 \| ITGAL \| 2.765 \| DISEASES 3684 \| ITGAM \| 4.311 \| DISEASES 3684 \| ITGAM \| 3.819 \| DISEASES 3704 \| ITPA \| 3.206 \| DISEASES 3704 \| ITPA \| 2.423 \| DISEASES 3712 \| IVD \| 1.208 \| DISEASES 3712 \| IVD \| 1.2 \| DISEASES 3716 \| JAK1 \| 1.185 \| DISEASES 3716 \| JAK1 \| 1.052 \| DISEASES 3717 \| JAK2 \| 2.55 \| DISEASES 3717 \| JAK2 \| 2.393 \| DISEASES 3718 \| JAK3 \| 2.327 \| DISEASES 3725 \| JUN \| 1.426 \| DISEASES 9920 \| KBTBD11 \| 3.195 \| DISEASES 9920 \| KBTBD11 \| 2.935 \| DISEASES 3767 \| KCNJ11 \| 2.202 \| DISEASES 3767 \| KCNJ11 \| 2.046 \| DISEASES 55614 \| KIF16B \| 1.887 \| DISEASES 55614 \| KIF16B \| 1.19 \| DISEASES 5650 \| KLK7 \| 2.235 \| DISEASES 5650 \| KLK7 \| 1.974 \| DISEASES 3824 \| KLRD1 \| 1.182 \| DISEASES 28956 \| LAMTOR2 \| 2.62 \| DISEASES 28956 \| LAMTOR2 \| 2.359 \| DISEASES 27040 \| LAT \| 1.444 \| DISEASES 3932 \| LCK \| 2.956 \| DISEASES 3981 \| LIG4 \| 1.37 \| DISEASES 3996 \| LLGL1 \| 1.204 \| DISEASES 25802 \| LMOD1 \| 1.645 \| DISEASES 25802 \| LMOD1 \| 1.384 \| DISEASES 9361 \| LONP1 \| 1.404 \| DISEASES 9361 \| LONP1 \| 1.143 \| DISEASES 1130 \| LYST \| 1.812 \| DISEASES 1130 \| LYST \| 1.552 \| DISEASES 84061 \| MAGT1 \| 2.18 \| DISEASES 5609 \| MAP2K7 \| 1.574 \| DISEASES 5609 \| MAP2K7 \| 1.43 \| DISEASES 23542 \| MAPK8IP2 \| 3.863 \| DISEASES 23542 \| MAPK8IP2 \| 3.809 \| DISEASES 65108 \| MARCKSL1 \| 1.4 \| DISEASES 10747 \| MASP2 \| 2.02 \| DISEASES 10747 \| MASP2 \| 1.759 \| DISEASES 4145 \| MATK \| 1.569 \| DISEASES 4145 \| MATK \| 1.526 \| DISEASES 4153 \| MBL2 \| 2.446 \| DISEASES 4153 \| MBL2 \| 2.246 \| DISEASES 4170 \| MCL1 \| 1.5 \| DISEASES 4170 \| MCL1 \| 1.201 \| DISEASES 79104 \| MEG8 \| 1.025 \| DISEASES 8972 \| MGAM \| 1.382 \| DISEASES 50488 \| MINK1 \| 1.659 \| DISEASES 114614 \| MIR155HG \| 1.315 \| DISEASES 114614 \| MIR155HG \| 1.055 \| DISEASES 4311 \| MME \| 2.211 \| DISEASES 4311 \| MME \| 1.279 \| DISEASES 4318 \| MMP9 \| 1.17 \| DISEASES 4352 \| MPL \| 2.506 \| DISEASES 4352 \| MPL \| 2.419 \| DISEASES 4524 \| MTHFR \| 2.585 \| DISEASES 4524 \| MTHFR \| 2.366 \| DISEASES 2475 \| MTOR \| 3.439 \| DISEASES 2475 \| MTOR \| 2.956 \| DISEASES 345778 \| MTX3 \| 2.514 \| DISEASES 345778 \| MTX3 \| 2.253 \| DISEASES 4582 \| MUC1 \| 1.163 \| DISEASES 4600 \| MX2 \| 1.788 \| DISEASES 4609 \| MYC \| 1.272 \| DISEASES 4615 \| MYD88 \| 1.027 \| DISEASES 29116 \| MYLIP \| 1.81 \| DISEASES 29116 \| MYLIP \| 1.55 \| DISEASES 114803 \| MYSM1 \| 2.927 \| DISEASES 10443 \| N4BP2L2 \| 1.867 \| DISEASES 10443 \| N4BP2L2 \| 1.606 \| DISEASES 4685 \| NCAM2 \| 1.25 \| DISEASES 4720 \| NDUFS2 \| 1.949 \| DISEASES 4720 \| NDUFS2 \| 1.901 \| DISEASES 79840 \| NHEJ1 \| 1.731 \| DISEASES 84504 \| NKX6-2 \| 3.755 \| DISEASES 84504 \| NKX6-2 \| 3.61 \| DISEASES 4868 \| NPHS1 \| 1.149 \| DISEASES 4835 \| NQO2 \| 2.499 \| DISEASES 131870 \| NUDT16 \| 3.323 \| DISEASES 131870 \| NUDT16 \| 3.28 \| DISEASES 4942 \| OAT \| 1.976 \| DISEASES 93377 \| OPALIN \| 1.284 \| DISEASES 93377 \| OPALIN \| 1.024 \| DISEASES 142 \| PARP1 \| 2.226 \| DISEASES 142 \| PARP1 \| 1.953 \| DISEASES 5091 \| PC \| 2.174 \| DISEASES 5091 \| PC \| 1.914 \| DISEASES 57060 \| PCBP4 \| 1.398 \| DISEASES 57060 \| PCBP4 \| 1.137 \| DISEASES 23590 \| PDSS1 \| 1.514 \| DISEASES 23590 \| PDSS1 \| 1.253 \| DISEASES 64065 \| PERP \| 1.481 \| DISEASES 64065 \| PERP \| 1.221 \| DISEASES 5228 \| PGF \| 1.132 \| DISEASES 5238 \| PGM3 \| 1.332 \| DISEASES 5238 \| PGM3 \| 1.048 \| DISEASES 5241 \| PGR \| 2.458 \| DISEASES 5241 \| PGR \| 2.444 \| DISEASES 80012 \| PHC3 \| 1.074 \| DISEASES 51230 \| PHF20 \| 1.481 \| DISEASES 51230 \| PHF20 \| 1.167 \| DISEASES 23612 \| PHLDA3 \| 1.076 \| DISEASES 5293 \| PIK3CD \| 1.589 \| DISEASES 5586 \| PKN2 \| 2.932 \| DISEASES 5586 \| PKN2 \| 2.885 \| DISEASES 200150 \| PLD5 \| 1.088 \| DISEASES 5350 \| PLN \| 1.281 \| DISEASES 57088 \| PLSCR4 \| 1.512 \| DISEASES 6490 \| PMEL \| 1.578 \| DISEASES 4860 \| PNP \| 2.06 \| DISEASES 9533 \| POLR1C \| 1.397 \| DISEASES 9533 \| POLR1C \| 1.136 \| DISEASES 5447 \| POR \| 1.792 \| DISEASES 5447 \| POR \| 1.532 \| DISEASES 28227 \| PPP2R3B \| 2.163 \| DISEASES 28227 \| PPP2R3B \| 1.902 \| DISEASES 9374 \| PPT2 \| 1.013 \| DISEASES 9588 \| PRDX6 \| 1.189 \| DISEASES 5562 \| PRKAA1 \| 1.07 \| DISEASES 5663 \| PSEN1 \| 3.608 \| DISEASES 5663 \| PSEN1 \| 3.525 \| DISEASES 5688 \| PSMA7 \| 1.623 \| DISEASES 5688 \| PSMA7 \| 1.621 \| DISEASES 56984 \| PSMG2 \| 3.143 \| DISEASES 56984 \| PSMG2 \| 2.882 \| DISEASES 5728 \| PTEN \| 1.826 \| DISEASES 5728 \| PTEN \| 1.514 \| DISEASES 5743 \| PTGS2 \| 1.719 \| DISEASES 5743 \| PTGS2 \| 1.478 \| DISEASES 5788 \| PTPRC \| 3.007 \| DISEASES 5788 \| PTPRC \| 1.438 \| DISEASES 9230 \| RAB11B \| 1.34 \| DISEASES 9230 \| RAB11B \| 1.079 \| DISEASES 5873 \| RAB27A \| 2.075 \| DISEASES 5873 \| RAB27A \| 1.815 \| DISEASES 9939 \| RBM8A \| 1.572 \| DISEASES 9939 \| RBM8A \| 1.312 \| DISEASES 51109 \| RDH11 \| 1.47 \| DISEASES 51109 \| RDH11 \| 1.037 \| DISEASES 5979 \| RET \| 2.095 \| DISEASES 5979 \| RET \| 1.949 \| DISEASES 56963 \| RGMA \| 2.439 \| DISEASES 56963 \| RGMA \| 2.379 \| DISEASES 83695 \| RHNO1 \| 1.738 \| DISEASES 83695 \| RHNO1 \| 1.686 \| DISEASES 6016 \| RIT1 \| 1.603 \| DISEASES 6016 \| RIT1 \| 1.273 \| DISEASES 6023 \| RMRP \| 1.19 \| DISEASES 6085 \| RNY3 \| 1.934 \| DISEASES 23322 \| RPGRIP1L \| 1.717 \| DISEASES 23322 \| RPGRIP1L \| 1.457 \| DISEASES 6223 \| RPS19 \| 1.08 \| DISEASES 6230 \| RPS25 \| 1.581 \| DISEASES 6230 \| RPS25 \| 1.321 \| DISEASES 84816 \| RTN4IP1 \| 1.017 \| DISEASES 1903 \| S1PR3 \| 1.048 \| DISEASES 53637 \| S1PR5 \| 2.109 \| DISEASES 83482 \| SCRT1 \| 1.094 \| DISEASES 6401 \| SELE \| 1.628 \| DISEASES 6401 \| SELE \| 1.069 \| DISEASES 256987 \| SERINC5 \| 1.024 \| DISEASES 5265 \| SERPINA1 \| 1.454 \| DISEASES 462 \| SERPINC1 \| 2.289 \| DISEASES 8879 \| SGPL1 \| 1.953 \| DISEASES 4990 \| SIX6 \| 1.08 \| DISEASES 57823 \| SLAMF7 \| 1.674 \| DISEASES 9058 \| SLC13A2 \| 3.54 \| DISEASES 9058 \| SLC13A2 \| 3.467 \| DISEASES 284111 \| SLC13A5 \| 3.546 \| DISEASES 284111 \| SLC13A5 \| 3.473 \| DISEASES 91137 \| SLC25A46 \| 1.24 \| DISEASES 64078 \| SLC28A3 \| 1.721 \| DISEASES 64078 \| SLC28A3 \| 1.461 \| DISEASES 2030 \| SLC29A1 \| 2.235 \| DISEASES 2030 \| SLC29A1 \| 2.116 \| DISEASES 10559 \| SLC35A1 \| 1.434 \| DISEASES 10559 \| SLC35A1 \| 1.174 \| DISEASES 347734 \| SLC35B2 \| 1.184 \| DISEASES 83650 \| SLC35G5 \| 2.453 \| DISEASES 83650 \| SLC35G5 \| 2.446 \| DISEASES 54020 \| SLC37A1 \| 1.68 \| DISEASES 54020 \| SLC37A1 \| 1.419 \| DISEASES 84255 \| SLC37A3 \| 1.477 \| DISEASES 84255 \| SLC37A3 \| 1.216 \| DISEASES 57153 \| SLC44A2 \| 1.734 \| DISEASES 57153 \| SLC44A2 \| 1.473 \| DISEASES 338821 \| SLCO1B7 \| 2.094 \| DISEASES 338821 \| SLCO1B7 \| 1.834 \| DISEASES 6603 \| SMARCD2 \| 1.441 \| DISEASES 6603 \| SMARCD2 \| 1.181 \| DISEASES 23583 \| SMUG1 \| 2.269 \| DISEASES 23583 \| SMUG1 \| 2.098 \| DISEASES 26770 \| SNORD79 \| 1.045 \| DISEASES 6625 \| SNRNP70 \| 1.083 \| DISEASES 6693 \| SPN \| 2.038 \| DISEASES 124976 \| SPNS2 \| 2.568 \| DISEASES 10011 \| SRA1 \| 1.509 \| DISEASES 10011 \| SRA1 \| 1.461 \| DISEASES 6714 \| SRC \| 1.935 \| DISEASES 6714 \| SRC \| 1.852 \| DISEASES 6772 \| STAT1 \| 1.893 \| DISEASES 6772 \| STAT1 \| 1.323 \| DISEASES 6776 \| STAT5A \| 2.69 \| DISEASES 6776 \| STAT5A \| 2.355 \| DISEASES 6789 \| STK4 \| 1.325 \| DISEASES 6789 \| STK4 \| 1.065 \| DISEASES 25870 \| SUMF2 \| 1.671 \| DISEASES 25870 \| SUMF2 \| 1.411 \| DISEASES 6850 \| SYK \| 2.51 \| DISEASES 6850 \| SYK \| 2.394 \| DISEASES 6863 \| TAC1 \| 1.084 \| DISEASES 4070 \| TACSTD2 \| 1.328 \| DISEASES 4070 \| TACSTD2 \| 1.067 \| DISEASES 138474 \| TAF1L \| 1.742 \| DISEASES 138474 \| TAF1L \| 1.481 \| DISEASES 55775 \| TDP1 \| 1.006 \| DISEASES 7010 \| TEK \| 1.139 \| DISEASES 54790 \| TET2 \| 4.028 \| DISEASES 54790 \| TET2 \| 3.697 \| DISEASES 7018 \| TF \| 2.36 \| DISEASES 7018 \| TF \| 1.599 \| DISEASES 7037 \| TFRC \| 2.4 \| DISEASES 51337 \| THEM6 \| 1.72 \| DISEASES 51337 \| THEM6 \| 1.023 \| DISEASES 353376 \| TICAM2 \| 1.108 \| DISEASES 1678 \| TIMM8A \| 2.158 \| DISEASES 1678 \| TIMM8A \| 2.11 \| DISEASES 7086 \| TKT \| 2.208 \| DISEASES 7086 \| TKT \| 2.11 \| DISEASES 7099 \| TLR4 \| 1.876 \| DISEASES 51284 \| TLR7 \| 1.866 \| DISEASES 54106 \| TLR9 \| 2.045 \| DISEASES 54106 \| TLR9 \| 1.837 \| DISEASES 7124 \| TNF \| 4.489 \| DISEASES 7124 \| TNF \| 3.472 \| DISEASES 7133 \| TNFRSF1B \| 2.534 \| DISEASES 7133 \| TNFRSF1B \| 1.935 \| DISEASES 8718 \| TNFRSF25 \| 2.119 \| DISEASES 3604 \| TNFRSF9 \| 1.292 \| DISEASES 10673 \| TNFSF13B \| 2.321 \| DISEASES 10673 \| TNFSF13B \| 1.541 \| DISEASES 7150 \| TOP1 \| 5.431 \| DISEASES 7150 \| TOP1 \| 5.376 \| DISEASES 7153 \| TOP2A \| 1.313 \| DISEASES 7153 \| TOP2A \| 1.052 \| DISEASES 7155 \| TOP2B \| 1.642 \| DISEASES 7155 \| TOP2B \| 1.381 \| DISEASES 9760 \| TOX \| 1.841 \| DISEASES 7174 \| TPP2 \| 1.281 \| DISEASES 127262 \| TPRG1L \| 2.656 \| DISEASES 127262 \| TPRG1L \| 2.395 \| DISEASES 6738 \| TROVE2 \| 1.101 \| DISEASES 51393 \| TRPV2 \| 3.421 \| DISEASES 51393 \| TRPV2 \| 3.331 \| DISEASES 54970 \| TTC12 \| 2.674 \| DISEASES 54970 \| TTC12 \| 2.413 \| DISEASES 7272 \| TTK \| 1.646 \| DISEASES 7272 \| TTK \| 1.386 \| DISEASES 55833 \| UBAP2 \| 1.531 \| DISEASES 55833 \| UBAP2 \| 1.271 \| DISEASES 54577 \| UGT1A7 \| 2.519 \| DISEASES 54577 \| UGT1A7 \| 2.389 \| DISEASES 54600 \| UGT1A9 \| 2.419 \| DISEASES 54600 \| UGT1A9 \| 2.052 \| DISEASES 9094 \| UNC119 \| 4.119 \| DISEASES 9218 \| VAPA \| 1.1 \| DISEASES 7409 \| VAV1 \| 1.273 \| DISEASES 7422 \| VEGFA \| 3.371 \| DISEASES 7422 \| VEGFA \| 3.252 \| DISEASES 27287 \| VENTX \| 1.281 \| DISEASES 27287 \| VENTX \| 1.021 \| DISEASES 157680 \| VPS13B \| 4.422 \| DISEASES 157680 \| VPS13B \| 4.269 \| DISEASES 11311 \| VPS45 \| 3.452 \| DISEASES 11311 \| VPS45 \| 3.191 \| DISEASES 7454 \| WAS \| 3.506 \| DISEASES 7454 \| WAS \| 3.468 \| DISEASES 23038 \| WDTC1 \| 1.491 \| DISEASES 23038 \| WDTC1 \| 1.004 \| DISEASES 51741 \| WWOX \| 3.702 \| DISEASES 51741 \| WWOX \| 3.409 \| DISEASES 7517 \| XRCC3 \| 2.288 \| DISEASES 7517 \| XRCC3 \| 2.027 \| DISEASES 340152 \| ZC3H12D \| 2.66 \| DISEASES 340152 \| ZC3H12D \| 2.399 \| DISEASES 79670 \| ZCCHC6 \| 1.747 \| DISEASES 79670 \| ZCCHC6 \| 1.051 \| DISEASES 161882 \| ZFPM1 \| 1.014 \| DISEASES
Locus	(Waiting for update.)

Disease ID	588
Disease	neutropenia
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:131) HP:0001945 \| Fever \| 53 HP:0100806 \| Sepsis \| 33 HP:0001903 \| Anemia \| 27 HP:0002664 \| Neoplasia \| 21 HP:0001873 \| Low platelet count \| 21 HP:0001029 \| Poikiloderma \| 18 HP:0003002 \| Breast carcinoma \| 16 HP:0001882 \| Decreased blood leukocyte number \| 16 HP:0001888 \| Lymphocytopenia \| 15 HP:0001909 \| Leukemia \| 11 HP:0002090 \| Pneumonia \| 11 HP:0001875 \| Neutropenia \| 10 HP:0002719 \| infections, recurrent \| 9 HP:0002665 \| Lymphoma \| 9 HP:0004808 \| Acute myelogenous leukemia \| 8 HP:0012115 \| Liver inflammation \| 7 HP:0100827 \| Lymphocytosis \| 7 HP:0001971 \| Hypersplenism \| 7 HP:0002721 \| Immunodeficiency \| 6 HP:0002488 \| Acute leukemias \| 6 HP:0012189 \| Hodgkin disease \| 6 HP:0012324 \| Myeloid leukemia \| 5 HP:0000822 \| Hypertension \| 5 HP:0001878 \| Haemolytic anaemia \| 5 HP:0001369 \| Arthritis \| 4 HP:0002718 \| Recurrent pyogenic infections \| 4 HP:0006775 \| Multiple myeloma \| 4 HP:0002725 \| Systemic lupus erythematosus \| 4 HP:0002863 \| Myelodysplastic syndrome \| 4 HP:0001370 \| Rheumatoid arthritis \| 4 HP:0200123 \| Chronic liver inflammation \| 4 HP:0003198 \| Myopathic changes \| 4 HP:0001876 \| Low blood cell count \| 4 HP:0002018 \| Nausea \| 4 HP:0012378 \| Fatigue \| 4 HP:0001744 \| Splenomegaly \| 3 HP:0040187 \| Neonatal sepsis \| 3 HP:0012311 \| High blood monocyte number \| 3 HP:0001913 \| Granulocytopenia \| 3 HP:0100658 \| Bacterial infection of skin \| 3 HP:0030358 \| Non-small cell lung carcinoma \| 3 HP:0011947 \| Respiratory infection \| 3 HP:0030357 \| Small cell lung carcinoma \| 3 HP:0012539 \| Non-Hodgkin lymphoma \| 3 HP:0005528 \| Bone marrow hypoplasia \| 2 HP:0010783 \| Erythema \| 2 HP:0010280 \| Stomatitis \| 2 HP:0001638 \| Cardiomyopathy \| 2 HP:0012234 \| Agranulocytosis \| 2 HP:0011967 \| Hypocupremia \| 2 HP:0005387 \| Combined immunodeficiency \| 2 HP:0002633 \| Vasculitis \| 2 HP:0010702 \| Hypergammaglobulinaemia \| 2 HP:0001394 \| Hepatic cirrhosis \| 2 HP:0002014 \| Diarrhea \| 2 HP:0030448 \| Soft tissue sarcoma \| 2 HP:0012312 \| Low blood monocyte number \| 2 HP:0004430 \| Severe combined immunodeficiency \| 2 HP:0002894 \| Neoplasia of the pancreas \| 2 HP:0002352 \| Leukoencephalopathy \| 2 HP:0003074 \| High blood glucose \| 1 HP:0000819 \| Diabetes mellitus \| 1 HP:0001733 \| Pancreatic inflammation \| 1 HP:0005584 \| Renal cell carcinoma \| 1 HP:0012126 \| Gastric cancer \| 1 HP:0000999 \| Pyoderma \| 1 HP:0001279 \| Syncope \| 1 HP:0001941 \| acidemia \| 1 HP:0002027 \| Abdominal pain \| 1 HP:0001972 \| Macrocytic anemia \| 1 HP:0001915 \| Aplastic anemia \| 1 HP:0001824 \| Weight loss \| 1 HP:0000554 \| Uveitis \| 1 HP:0002878 \| Respiratory failure \| 1 HP:0000159 \| Lip abnormality \| 1 HP:0001924 \| Hypersideremic anemia \| 1 HP:0100819 \| Intestinal fistula \| 1 HP:0001894 \| Thrombocytosis \| 1 HP:0003470 \| Inability to move \| 1 HP:0100633 \| Inflammation of the esophagus \| 1 HP:0001978 \| Extramedullary hematopoiesis \| 1 HP:0001897 \| Normocytic anemia \| 1 HP:0002094 \| Dyspnea \| 1 HP:0000488 \| Noninflammatory retina disease \| 1 HP:0006721 \| Acute lymphocytic leukemia \| 1 HP:0000155 \| Oral ulcer \| 1 HP:0000709 \| Psychosis \| 1 HP:0009733 \| Glioma \| 1 HP:0000010 \| Frequent urinary tract infections \| 1 HP:0200029 \| Cutaneous vasculitis \| 1 HP:0001596 \| Hair loss \| 1 HP:0001402 \| Hepatocellular carcinoma \| 1 HP:0001409 \| Portal hypertension \| 1 HP:0002113 \| Pulmonary infiltrates \| 1 HP:0005508 \| Waldenstrom macroglobulinemia \| 1 HP:0004387 \| Enterocolitis \| 1 HP:0000969 \| Dropsy \| 1 HP:0000491 \| Corneal inflammation \| 1 HP:0008151 \| Prolonged prothrombin time \| 1 HP:0001287 \| Meningitis \| 1 HP:0000704 \| Pyorrhea \| 1 HP:0003003 \| Colon cancer \| 1 HP:0002092 \| Pulmonary artery hypertension \| 1 HP:0030731 \| Carcinoma \| 1 HP:0003737 \| Mitochondrial myopathy \| 1 HP:0003453 \| Antineutrophil antibodies \| 1 HP:0001404 \| Hepatocellular necrosis \| 1 HP:0100723 \| Gastrointestinal stroma tumor \| 1 HP:0011034 \| Amyloid disease \| 1 HP:0100753 \| Schizophrenia \| 1 HP:0001942 \| Metabolic acidosis \| 1 HP:0012735 \| Coughing \| 1 HP:0006689 \| Bacterial endocarditis \| 1 HP:0002202 \| Pleural effusion \| 1 HP:0001602 \| Laryngeal stenosis \| 1 HP:0002754 \| Bone infection \| 1 HP:0002586 \| Peritonitis \| 1 HP:0100602 \| Pre-eclampsia \| 1 HP:0002608 \| Celiac disease \| 1 HP:0002615 \| Low blood pressure \| 1 HP:0012531 \| Pain \| 1 HP:0000716 \| Depression \| 1 HP:0002583 \| Colitis \| 1 HP:0002205 \| Frequent respiratory infections \| 1 HP:0008326 \| Vitamin B6 deficiency \| 1 HP:0000230 \| Inflamed gums \| 1 HP:0001644 \| Congestive cardiomyopathy \| 1 HP:0001880 \| Eosinophilia \| 1 HP:0008071 \| Maternal hypertension \| 1 HP:0002960 \| Autoimmune condition \| 1 HP:0000988 \| Exanthem \| 1

Disease ID	588
Disease	neutropenia
Manually Symptom	UMLS \| Name(Total Manually Symptoms:48) C2707258 \| infections C2364133 \| infection C1963091 \| diarrhea C1844383 \| recurrent bacterial infections C1719672 \| severe sepsis C1609535 \| invasive candidiasis C1142423 \| staphylococcus aureus bacteremia C1096584 \| chlamydia pneumoniae infection C1090821 \| sepsis C0752179 \| herpes zoster meningoencephalitis C0744471 \| gram-negative bacteraemia C0684256 \| bacterial septicemia C0520459 \| necrotizing enterocolitis C0424755 \| fever C0343386 \| clostridium difficile infection C0343039 \| subcutaneous zygomycosis C0276653 \| invasive pulmonary aspergillosis C0272278 \| congenital thrombocytopenia C0178829 \| genital disorder C0175683 \| citrullinemia C0152964 \| streptococcal bacteraemia C0151465 \| kidney abscess C0149925 \| small cell lung cancer C0085394 \| serratia infections C0042769 \| viral infections C0041296 \| tuberculosis C0038395 \| streptococcal infections C0036690 \| septicemia C0036685 \| gram-negative septicemia C0033817 \| pseudomonas infection C0032285 \| pneumonia C0028992 \| omphalitis C0026946 \| mycoses C0026946 \| fungal infections C0026946 \| fungal infection C0025289 \| meningitis C0024305 \| non-hodgkin's lymphoma C0024291 \| hemophagocytic syndrome C0023530 \| leukopenia C0023439 \| acute eosinophilic leukemia C0015970 \| fever of unknown origin C0014733 \| erysipelas C0009324 \| ulcerative colitis C0006840 \| candidiasis C0004623 \| bacterial infections C0004623 \| bacterial infection C0004610 \| bacteremia C0004030 \| aspergillosis
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:24) C0009450 \| infection \| 59 C0021311 \| infections \| 58 C0015967 \| fever \| 50 C0036690 \| sepsis \| 31 C0023530 \| leukopenia \| 16 C0026946 \| fungal infection \| 7 C0032285 \| pneumonia \| 7 C0004610 \| bacteremia \| 6 C0027947 \| neutropenia \| 6 C0004623 \| bacterial infections \| 5 C0004030 \| aspergillosis \| 4 C1844383 \| recurrent bacterial infections \| 4 C0004623 \| bacterial infection \| 4 C0149925 \| small cell lung cancer \| 3 C0024305 \| non-hodgkin's lymphoma \| 3 C0276653 \| invasive pulmonary aspergillosis \| 3 C1719672 \| severe sepsis \| 3 C0006840 \| candidiasis \| 2 C0011991 \| diarrhea \| 2 C0743841 \| febrile illness \| 2 C0026946 \| fungal infections \| 2 C0036690 \| septicemia \| 1 C0024291 \| hemophagocytic syndrome \| 1 C0025289 \| meningitis \| 1

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

Text Mining Genotype(Total Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:96)
snpId	pubmedId	geneId	geneSymbol	diseaseId	sourceId	sentence	score	Year	geneSymbol_dbSNP	CHROMOSOME	POS	REF	ALT
rs1042522	24732641	7157	TP53	umls:C0023530	BeFree	MDM2 rs2279744 and TP53 rs1042522 polymorphisms associated with etoposide- and cisplatin-induced grade III/IV neutropenia in Chinese extensive-stage small-cell lung cancer patients.	0.000814326	2014	TP53	17	7676154	G	T,C
rs1042522	24732641	4193	MDM2	umls:C0023530	BeFree	MDM2 rs2279744 and TP53 rs1042522 polymorphisms associated with etoposide- and cisplatin-induced grade III/IV neutropenia in Chinese extensive-stage small-cell lung cancer patients.	0.000542884	2014	TP53	17	7676154	G	T,C
rs1042522	21706156	4193	MDM2	umls:C0023530	BeFree	MDM2 SNP309 and TP53 R72P are significantly associated with severe neutropenia and FN, respectively, in breast cancer patients treated with FEC100, and especially their combination may be a useful predictor of severe neutropenia and FN.	0.000542884	2012	TP53	17	7676154	G	T,C
rs1042522	21706156	4193	MDM2	umls:C0027947	BeFree	MDM2 SNP309 and TP53 R72P are significantly associated with severe neutropenia and FN, respectively, in breast cancer patients treated with FEC100, and especially their combination may be a useful predictor of severe neutropenia and FN.	0.000542884	2012	TP53	17	7676154	G	T,C
rs1042522	21706156	7157	TP53	umls:C0027947	BeFree	MDM2 SNP309 and TP53 R72P are significantly associated with severe neutropenia and FN, respectively, in breast cancer patients treated with FEC100, and especially their combination may be a useful predictor of severe neutropenia and FN.	0.000814326	2012	TP53	17	7676154	G	T,C
rs1042522	21706156	7157	TP53	umls:C0023530	BeFree	MDM2 SNP309 and TP53 R72P are significantly associated with severe neutropenia and FN, respectively, in breast cancer patients treated with FEC100, and especially their combination may be a useful predictor of severe neutropenia and FN.	0.000814326	2012	TP53	17	7676154	G	T,C
rs1042522	24732641	4193	MDM2	umls:C0027947	BeFree	MDM2 rs2279744 and TP53 rs1042522 polymorphisms associated with etoposide- and cisplatin-induced grade III/IV neutropenia in Chinese extensive-stage small-cell lung cancer patients.	0.000542884	2014	TP53	17	7676154	G	T,C
rs1042522	24732641	7157	TP53	umls:C0027947	BeFree	MDM2 rs2279744 and TP53 rs1042522 polymorphisms associated with etoposide- and cisplatin-induced grade III/IV neutropenia in Chinese extensive-stage small-cell lung cancer patients.	0.000814326	2014	TP53	17	7676154	G	T,C
rs1045642	19349543	54658	UGT1A1	umls:C0027947	BeFree	PG analysis showed that ABCB1 (C3435T)T/T (membrane transport) was associated with IP-related diarrhea; UGT1A1 (G-3156A)A/A (drug metabolism) was associated with IP-related neutropenia.	0.14695996	2009	ABCB1	7	87509329	A	T,G
rs1045642	19349543	5243	ABCB1	umls:C0027947	BeFree	PG analysis showed that ABCB1 (C3435T)T/T (membrane transport) was associated with IP-related diarrhea; UGT1A1 (G-3156A)A/A (drug metabolism) was associated with IP-related neutropenia.	0.129815515	2009	ABCB1	7	87509329	A	T,G
rs1045642	19349543	5243	ABCB1	umls:C0023530	BeFree	PG analysis showed that ABCB1 (C3435T)T/T (membrane transport) was associated with IP-related diarrhea; UGT1A1 (G-3156A)A/A (drug metabolism) was associated with IP-related neutropenia.	0.005895776	2009	ABCB1	7	87509329	A	T,G
rs1045642	21327421	5243	ABCB1	umls:C0023530	BeFree	CYP2C8*3 and the ABCB1 SNPs C1236T, G2677T/A, and C3435T were not statistically significantly correlated to overall survival, sensoric neuropathy, and neutropenia in 119 patients treated for ovarian cancer with paclitaxel/carboplatin.	0.005895776	2011	ABCB1	7	87509329	A	T,G
rs1045642	21327421	1558	CYP2C8	umls:C0023530	BeFree	CYP2C8*3 and the ABCB1 SNPs C1236T, G2677T/A, and C3435T were not statistically significantly correlated to overall survival, sensoric neuropathy, and neutropenia in 119 patients treated for ovarian cancer with paclitaxel/carboplatin.	0.000271442	2011	ABCB1	7	87509329	A	T,G
rs1045642	21327421	5243	ABCB1	umls:C0027947	BeFree	CYP2C8*3 and the ABCB1 SNPs C1236T, G2677T/A, and C3435T were not statistically significantly correlated to overall survival, sensoric neuropathy, and neutropenia in 119 patients treated for ovarian cancer with paclitaxel/carboplatin.	0.129815515	2011	ABCB1	7	87509329	A	T,G
rs1045642	25007187	5243	ABCB1	umls:C0023530	BeFree	In addition, a statistically significant association was found among neutropenia (absolute neutrophil count<500) and variant allele carriers of ABCB1 rs1045642 (OR=5.174; 95% CI: 1.674; 15.989) and ABCB1 rs1128503 (OR=3.364; 95% CI: 1.257; 9.004), respectively.	0.005895776	2014	ABCB1	7	87509329	A	T,G
rs1045642	21327421	1558	CYP2C8	umls:C0027947	BeFree	CYP2C8*3 and the ABCB1 SNPs C1236T, G2677T/A, and C3435T were not statistically significantly correlated to overall survival, sensoric neuropathy, and neutropenia in 119 patients treated for ovarian cancer with paclitaxel/carboplatin.	0.000271442	2011	ABCB1	7	87509329	A	T,G
rs1045642	21706123	5243	ABCB1	umls:C0023530	BeFree	Serum LDH may be a promising predictor of prognosis, and the ABCB1 C3435T polymorphism may be a genetic predictor of the severity of leukocytopenia in patients with CRPC treated with DEC.	0.005895776	2012	ABCB1	7	87509329	A	T,G
rs1045642	25007187	5243	ABCB1	umls:C0027947	BeFree	In addition, a statistically significant association was found among neutropenia (absolute neutrophil count<500) and variant allele carriers of ABCB1 rs1045642 (OR=5.174; 95% CI: 1.674; 15.989) and ABCB1 rs1128503 (OR=3.364; 95% CI: 1.257; 9.004), respectively.	0.129815515	2014	ABCB1	7	87509329	A	T,G
rs1045642	19349543	54658	UGT1A1	umls:C0023530	BeFree	PG analysis showed that ABCB1 (C3435T)T/T (membrane transport) was associated with IP-related diarrhea; UGT1A1 (G-3156A)A/A (drug metabolism) was associated with IP-related neutropenia.	0.01302921	2009	ABCB1	7	87509329	A	T,G
rs11045585	18294295	1244	ABCC2	umls:C0027947	BeFree	The combined analysis indicated a significant association of rs12762549 in ABCC2 (P = 0.00022) and rs11045585 in SLCO1B3 (P = 0.00017) with docetaxel-induced leukopenia/neutropenia.	0.008544182	2008	SLCO1B3	12	20892760	A	G
rs11141915	22293537	1612	DAPK1	umls:C0027947	BeFree	We identified four loci possibly associated with gemcitabine-induced leukopenia/neutropenia [rs11141915 in DAPK1 on chromosome 9q21, combined P=1.27×10, odds ratio (OR)=4.10; rs1901440 on chromosome 2q12, combined P=3.11×10, OR=34.00; rs12046844 in PDE4B on chromosome 1p31, combined P=4.56×10, OR=4.13; rs11719165 on chromosome 3q29, combined P=5.98×10, OR=2.60].	0.000271442	2012	DAPK1	9	87620879	A	C
rs11141915	22293537	1612	DAPK1	umls:C0023530	BeFree	We identified four loci possibly associated with gemcitabine-induced leukopenia/neutropenia [rs11141915 in DAPK1 on chromosome 9q21, combined P=1.27×10, odds ratio (OR)=4.10; rs1901440 on chromosome 2q12, combined P=3.11×10, OR=34.00; rs12046844 in PDE4B on chromosome 1p31, combined P=4.56×10, OR=4.13; rs11719165 on chromosome 3q29, combined P=5.98×10, OR=2.60].	0.000271442	2012	DAPK1	9	87620879	A	C
rs11141915	22293537	5142	PDE4B	umls:C0023530	BeFree	We identified four loci possibly associated with gemcitabine-induced leukopenia/neutropenia [rs11141915 in DAPK1 on chromosome 9q21, combined P=1.27×10, odds ratio (OR)=4.10; rs1901440 on chromosome 2q12, combined P=3.11×10, OR=34.00; rs12046844 in PDE4B on chromosome 1p31, combined P=4.56×10, OR=4.13; rs11719165 on chromosome 3q29, combined P=5.98×10, OR=2.60].	0.000271442	2012	DAPK1	9	87620879	A	C
rs11141915	22293537	5142	PDE4B	umls:C0027947	BeFree	We identified four loci possibly associated with gemcitabine-induced leukopenia/neutropenia [rs11141915 in DAPK1 on chromosome 9q21, combined P=1.27×10, odds ratio (OR)=4.10; rs1901440 on chromosome 2q12, combined P=3.11×10, OR=34.00; rs12046844 in PDE4B on chromosome 1p31, combined P=4.56×10, OR=4.13; rs11719165 on chromosome 3q29, combined P=5.98×10, OR=2.60].	0.000271442	2012	DAPK1	9	87620879	A	C
rs1128503	25007187	5243	ABCB1	umls:C0023530	BeFree	In addition, a statistically significant association was found among neutropenia (absolute neutrophil count<500) and variant allele carriers of ABCB1 rs1045642 (OR=5.174; 95% CI: 1.674; 15.989) and ABCB1 rs1128503 (OR=3.364; 95% CI: 1.257; 9.004), respectively.	0.005895776	2014	ABCB1	7	87550285	A	G
rs1128503	21327421	5243	ABCB1	umls:C0027947	BeFree	CYP2C8*3 and the ABCB1 SNPs C1236T, G2677T/A, and C3435T were not statistically significantly correlated to overall survival, sensoric neuropathy, and neutropenia in 119 patients treated for ovarian cancer with paclitaxel/carboplatin.	0.129815515	2011	ABCB1	7	87550285	A	G
rs1128503	21327421	5243	ABCB1	umls:C0023530	BeFree	CYP2C8*3 and the ABCB1 SNPs C1236T, G2677T/A, and C3435T were not statistically significantly correlated to overall survival, sensoric neuropathy, and neutropenia in 119 patients treated for ovarian cancer with paclitaxel/carboplatin.	0.005895776	2011	ABCB1	7	87550285	A	G
rs1128503	21327421	1558	CYP2C8	umls:C0027947	BeFree	CYP2C8*3 and the ABCB1 SNPs C1236T, G2677T/A, and C3435T were not statistically significantly correlated to overall survival, sensoric neuropathy, and neutropenia in 119 patients treated for ovarian cancer with paclitaxel/carboplatin.	0.000271442	2011	ABCB1	7	87550285	A	G
rs1128503	25007187	5243	ABCB1	umls:C0027947	BeFree	In addition, a statistically significant association was found among neutropenia (absolute neutrophil count<500) and variant allele carriers of ABCB1 rs1045642 (OR=5.174; 95% CI: 1.674; 15.989) and ABCB1 rs1128503 (OR=3.364; 95% CI: 1.257; 9.004), respectively.	0.129815515	2014	ABCB1	7	87550285	A	G
rs1128503	21327421	1558	CYP2C8	umls:C0023530	BeFree	CYP2C8*3 and the ABCB1 SNPs C1236T, G2677T/A, and C3435T were not statistically significantly correlated to overall survival, sensoric neuropathy, and neutropenia in 119 patients treated for ovarian cancer with paclitaxel/carboplatin.	0.000271442	2011	ABCB1	7	87550285	A	G
rs11540654	21706156	4193	MDM2	umls:C0023530	BeFree	MDM2 SNP309 and TP53 R72P are significantly associated with severe neutropenia and FN, respectively, in breast cancer patients treated with FEC100, and especially their combination may be a useful predictor of severe neutropenia and FN.	0.000542884	2012	TP53	17	7676040	C	T,G,A
rs11540654	21706156	4193	MDM2	umls:C0027947	BeFree	MDM2 SNP309 and TP53 R72P are significantly associated with severe neutropenia and FN, respectively, in breast cancer patients treated with FEC100, and especially their combination may be a useful predictor of severe neutropenia and FN.	0.000542884	2012	TP53	17	7676040	C	T,G,A
rs11540654	21706156	7157	TP53	umls:C0023530	BeFree	MDM2 SNP309 and TP53 R72P are significantly associated with severe neutropenia and FN, respectively, in breast cancer patients treated with FEC100, and especially their combination may be a useful predictor of severe neutropenia and FN.	0.000814326	2012	TP53	17	7676040	C	T,G,A
rs11540654	21706156	7157	TP53	umls:C0027947	BeFree	MDM2 SNP309 and TP53 R72P are significantly associated with severe neutropenia and FN, respectively, in breast cancer patients treated with FEC100, and especially their combination may be a useful predictor of severe neutropenia and FN.	0.000814326	2012	TP53	17	7676040	C	T,G,A
rs11706052	20061166	3615	IMPDH2	umls:C0027947	BeFree	The IMPDH2 rs11706052 G variant was associated with more frequent neutropenia requiring dose-holding (p = 0.046).	0.000271442	2010	IMPDH2	3	49026677	A	G
rs11706052	20061166	3615	IMPDH2	umls:C0023530	BeFree	The IMPDH2 rs11706052 G variant was associated with more frequent neutropenia requiring dose-holding (p = 0.046).	0.000271442	2010	IMPDH2	3	49026677	A	G
rs11719165	22293537	5142	PDE4B	umls:C0023530	BeFree	We identified four loci possibly associated with gemcitabine-induced leukopenia/neutropenia [rs11141915 in DAPK1 on chromosome 9q21, combined P=1.27×10, odds ratio (OR)=4.10; rs1901440 on chromosome 2q12, combined P=3.11×10, OR=34.00; rs12046844 in PDE4B on chromosome 1p31, combined P=4.56×10, OR=4.13; rs11719165 on chromosome 3q29, combined P=5.98×10, OR=2.60].	0.000271442	2012	NA	3	194865359	T	C
rs11719165	22293537	1612	DAPK1	umls:C0027947	BeFree	We identified four loci possibly associated with gemcitabine-induced leukopenia/neutropenia [rs11141915 in DAPK1 on chromosome 9q21, combined P=1.27×10, odds ratio (OR)=4.10; rs1901440 on chromosome 2q12, combined P=3.11×10, OR=34.00; rs12046844 in PDE4B on chromosome 1p31, combined P=4.56×10, OR=4.13; rs11719165 on chromosome 3q29, combined P=5.98×10, OR=2.60].	0.000271442	2012	NA	3	194865359	T	C
rs11719165	22293537	5142	PDE4B	umls:C0027947	BeFree	We identified four loci possibly associated with gemcitabine-induced leukopenia/neutropenia [rs11141915 in DAPK1 on chromosome 9q21, combined P=1.27×10, odds ratio (OR)=4.10; rs1901440 on chromosome 2q12, combined P=3.11×10, OR=34.00; rs12046844 in PDE4B on chromosome 1p31, combined P=4.56×10, OR=4.13; rs11719165 on chromosome 3q29, combined P=5.98×10, OR=2.60].	0.000271442	2012	NA	3	194865359	T	C
rs11719165	22293537	1612	DAPK1	umls:C0023530	BeFree	We identified four loci possibly associated with gemcitabine-induced leukopenia/neutropenia [rs11141915 in DAPK1 on chromosome 9q21, combined P=1.27×10, odds ratio (OR)=4.10; rs1901440 on chromosome 2q12, combined P=3.11×10, OR=34.00; rs12046844 in PDE4B on chromosome 1p31, combined P=4.56×10, OR=4.13; rs11719165 on chromosome 3q29, combined P=5.98×10, OR=2.60].	0.000271442	2012	NA	3	194865359	T	C
rs12046844	22293537	1612	DAPK1	umls:C0023530	BeFree	We identified four loci possibly associated with gemcitabine-induced leukopenia/neutropenia [rs11141915 in DAPK1 on chromosome 9q21, combined P=1.27×10, odds ratio (OR)=4.10; rs1901440 on chromosome 2q12, combined P=3.11×10, OR=34.00; rs12046844 in PDE4B on chromosome 1p31, combined P=4.56×10, OR=4.13; rs11719165 on chromosome 3q29, combined P=5.98×10, OR=2.60].	0.000271442	2012	NA	1	65772696	G	A
rs12046844	22293537	5142	PDE4B	umls:C0027947	BeFree	We identified four loci possibly associated with gemcitabine-induced leukopenia/neutropenia [rs11141915 in DAPK1 on chromosome 9q21, combined P=1.27×10, odds ratio (OR)=4.10; rs1901440 on chromosome 2q12, combined P=3.11×10, OR=34.00; rs12046844 in PDE4B on chromosome 1p31, combined P=4.56×10, OR=4.13; rs11719165 on chromosome 3q29, combined P=5.98×10, OR=2.60].	0.000271442	2012	NA	1	65772696	G	A
rs12046844	22293537	5142	PDE4B	umls:C0023530	BeFree	We identified four loci possibly associated with gemcitabine-induced leukopenia/neutropenia [rs11141915 in DAPK1 on chromosome 9q21, combined P=1.27×10, odds ratio (OR)=4.10; rs1901440 on chromosome 2q12, combined P=3.11×10, OR=34.00; rs12046844 in PDE4B on chromosome 1p31, combined P=4.56×10, OR=4.13; rs11719165 on chromosome 3q29, combined P=5.98×10, OR=2.60].	0.000271442	2012	NA	1	65772696	G	A
rs12046844	22293537	1612	DAPK1	umls:C0027947	BeFree	We identified four loci possibly associated with gemcitabine-induced leukopenia/neutropenia [rs11141915 in DAPK1 on chromosome 9q21, combined P=1.27×10, odds ratio (OR)=4.10; rs1901440 on chromosome 2q12, combined P=3.11×10, OR=34.00; rs12046844 in PDE4B on chromosome 1p31, combined P=4.56×10, OR=4.13; rs11719165 on chromosome 3q29, combined P=5.98×10, OR=2.60].	0.000271442	2012	NA	1	65772696	G	A
rs12762549	18294295	1244	ABCC2	umls:C0027947	BeFree	The combined analysis indicated a significant association of rs12762549 in ABCC2 (P = 0.00022) and rs11045585 in SLCO1B3 (P = 0.00017) with docetaxel-induced leukopenia/neutropenia.	0.008544182	2008	NA	10	99861014	C	G
rs1695	23812950	2950	GSTP1	umls:C0023530	BeFree	On evaluating higher order gene-gene interaction models by MDR analysis, GSTM1 and GSTP1 Ile105Val; GSTM1 and GSTT1; and GSTT1 and GSTP1 Ile105Val showed significant association with treatment response, grade 2-4 anemia, and dose delay/reduction due to neutropenia (P=0.046, P=0.027, P=0.026), respectively.	0.002909916	2014	GSTP1	11	67585218	A	G
rs1695	23812950	2944	GSTM1	umls:C0023530	BeFree	On evaluating higher order gene-gene interaction models by MDR analysis, GSTM1 and GSTP1 Ile105Val; GSTM1 and GSTT1; and GSTT1 and GSTP1 Ile105Val showed significant association with treatment response, grade 2-4 anemia, and dose delay/reduction due to neutropenia (P=0.046, P=0.027, P=0.026), respectively.	0.000814326	2014	GSTP1	11	67585218	A	G
rs1695	23812950	2950	GSTP1	umls:C0027947	BeFree	On evaluating higher order gene-gene interaction models by MDR analysis, GSTM1 and GSTP1 Ile105Val; GSTM1 and GSTT1; and GSTT1 and GSTP1 Ile105Val showed significant association with treatment response, grade 2-4 anemia, and dose delay/reduction due to neutropenia (P=0.046, P=0.027, P=0.026), respectively.	0.002909916	2014	GSTP1	11	67585218	A	G
rs1695	23812950	2952	GSTT1	umls:C0023530	BeFree	On evaluating higher order gene-gene interaction models by MDR analysis, GSTM1 and GSTP1 Ile105Val; GSTM1 and GSTT1; and GSTT1 and GSTP1 Ile105Val showed significant association with treatment response, grade 2-4 anemia, and dose delay/reduction due to neutropenia (P=0.046, P=0.027, P=0.026), respectively.	0.000814326	2014	GSTP1	11	67585218	A	G
rs1695	23812950	2952	GSTT1	umls:C0027947	BeFree	On evaluating higher order gene-gene interaction models by MDR analysis, GSTM1 and GSTP1 Ile105Val; GSTM1 and GSTT1; and GSTT1 and GSTP1 Ile105Val showed significant association with treatment response, grade 2-4 anemia, and dose delay/reduction due to neutropenia (P=0.046, P=0.027, P=0.026), respectively.	0.002909916	2014	GSTP1	11	67585218	A	G
rs1695	23812950	2944	GSTM1	umls:C0027947	BeFree	On evaluating higher order gene-gene interaction models by MDR analysis, GSTM1 and GSTP1 Ile105Val; GSTM1 and GSTT1; and GSTT1 and GSTP1 Ile105Val showed significant association with treatment response, grade 2-4 anemia, and dose delay/reduction due to neutropenia (P=0.046, P=0.027, P=0.026), respectively.	0.003181358	2014	GSTP1	11	67585218	A	G
rs1901440	22293537	1612	DAPK1	umls:C0023530	BeFree	We identified four loci possibly associated with gemcitabine-induced leukopenia/neutropenia [rs11141915 in DAPK1 on chromosome 9q21, combined P=1.27×10, odds ratio (OR)=4.10; rs1901440 on chromosome 2q12, combined P=3.11×10, OR=34.00; rs12046844 in PDE4B on chromosome 1p31, combined P=4.56×10, OR=4.13; rs11719165 on chromosome 3q29, combined P=5.98×10, OR=2.60].	0.000271442	2012	NA	2	133680388	C	A
rs1901440	22293537	5142	PDE4B	umls:C0023530	BeFree	We identified four loci possibly associated with gemcitabine-induced leukopenia/neutropenia [rs11141915 in DAPK1 on chromosome 9q21, combined P=1.27×10, odds ratio (OR)=4.10; rs1901440 on chromosome 2q12, combined P=3.11×10, OR=34.00; rs12046844 in PDE4B on chromosome 1p31, combined P=4.56×10, OR=4.13; rs11719165 on chromosome 3q29, combined P=5.98×10, OR=2.60].	0.000271442	2012	NA	2	133680388	C	A
rs1901440	22293537	5142	PDE4B	umls:C0027947	BeFree	We identified four loci possibly associated with gemcitabine-induced leukopenia/neutropenia [rs11141915 in DAPK1 on chromosome 9q21, combined P=1.27×10, odds ratio (OR)=4.10; rs1901440 on chromosome 2q12, combined P=3.11×10, OR=34.00; rs12046844 in PDE4B on chromosome 1p31, combined P=4.56×10, OR=4.13; rs11719165 on chromosome 3q29, combined P=5.98×10, OR=2.60].	0.000271442	2012	NA	2	133680388	C	A
rs1901440	22293537	1612	DAPK1	umls:C0027947	BeFree	We identified four loci possibly associated with gemcitabine-induced leukopenia/neutropenia [rs11141915 in DAPK1 on chromosome 9q21, combined P=1.27×10, odds ratio (OR)=4.10; rs1901440 on chromosome 2q12, combined P=3.11×10, OR=34.00; rs12046844 in PDE4B on chromosome 1p31, combined P=4.56×10, OR=4.13; rs11719165 on chromosome 3q29, combined P=5.98×10, OR=2.60].	0.000271442	2012	NA	2	133680388	C	A
rs2032582	21327421	1558	CYP2C8	umls:C0023530	BeFree	CYP2C8*3 and the ABCB1 SNPs C1236T, G2677T/A, and C3435T were not statistically significantly correlated to overall survival, sensoric neuropathy, and neutropenia in 119 patients treated for ovarian cancer with paclitaxel/carboplatin.	0.000271442	2011	ABCB1	7	87531302	A	T,C
rs2032582	21327421	5243	ABCB1	umls:C0023530	BeFree	CYP2C8*3 and the ABCB1 SNPs C1236T, G2677T/A, and C3435T were not statistically significantly correlated to overall survival, sensoric neuropathy, and neutropenia in 119 patients treated for ovarian cancer with paclitaxel/carboplatin.	0.005895776	2011	ABCB1	7	87531302	A	T,C
rs2032582	21327421	1558	CYP2C8	umls:C0027947	BeFree	CYP2C8*3 and the ABCB1 SNPs C1236T, G2677T/A, and C3435T were not statistically significantly correlated to overall survival, sensoric neuropathy, and neutropenia in 119 patients treated for ovarian cancer with paclitaxel/carboplatin.	0.000271442	2011	ABCB1	7	87531302	A	T,C
rs2032582	21327421	5243	ABCB1	umls:C0027947	BeFree	CYP2C8*3 and the ABCB1 SNPs C1236T, G2677T/A, and C3435T were not statistically significantly correlated to overall survival, sensoric neuropathy, and neutropenia in 119 patients treated for ovarian cancer with paclitaxel/carboplatin.	0.129815515	2011	ABCB1	7	87531302	A	T,C
rs2244613	25611302	1244	ABCC2	umls:C0027947	BeFree	Reduced risk of neutropenia and diarrhoea was associated with ABCC2-24C/T (odds ratio (OR)=0.22, 0.06-0.85) and CES1 (rs2244613; OR=0.29, 0.09-0.89), respectively.	0.008544182	2014	CES1	16	55810697	G	T
rs2244613	25611302	1244	ABCC2	umls:C0023530	BeFree	Reduced risk of neutropenia and diarrhoea was associated with ABCC2-24C/T (odds ratio (OR)=0.22, 0.06-0.85) and CES1 (rs2244613; OR=0.29, 0.09-0.89), respectively.	0.003724241	2014	CES1	16	55810697	G	T
rs2244613	25611302	1066	CES1	umls:C0023530	BeFree	Reduced risk of neutropenia and diarrhoea was associated with ABCC2-24C/T (odds ratio (OR)=0.22, 0.06-0.85) and CES1 (rs2244613; OR=0.29, 0.09-0.89), respectively.	0.000271442	2014	CES1	16	55810697	G	T
rs2244613	25611302	1066	CES1	umls:C0027947	BeFree	Reduced risk of neutropenia and diarrhoea was associated with ABCC2-24C/T (odds ratio (OR)=0.22, 0.06-0.85) and CES1 (rs2244613; OR=0.29, 0.09-0.89), respectively.	0.000271442	2014	CES1	16	55810697	G	T
rs2279744	24732641	4193	MDM2	umls:C0023530	BeFree	MDM2 rs2279744 and TP53 rs1042522 polymorphisms associated with etoposide- and cisplatin-induced grade III/IV neutropenia in Chinese extensive-stage small-cell lung cancer patients.	0.000542884	2014	MDM2	12	68808800	T	G
rs2279744	24732641	7157	TP53	umls:C0027947	BeFree	MDM2 rs2279744 and TP53 rs1042522 polymorphisms associated with etoposide- and cisplatin-induced grade III/IV neutropenia in Chinese extensive-stage small-cell lung cancer patients.	0.000814326	2014	MDM2	12	68808800	T	G
rs2279744	24732641	4193	MDM2	umls:C0027947	BeFree	MDM2 rs2279744 and TP53 rs1042522 polymorphisms associated with etoposide- and cisplatin-induced grade III/IV neutropenia in Chinese extensive-stage small-cell lung cancer patients.	0.000542884	2014	MDM2	12	68808800	T	G
rs2279744	24732641	7157	TP53	umls:C0023530	BeFree	MDM2 rs2279744 and TP53 rs1042522 polymorphisms associated with etoposide- and cisplatin-induced grade III/IV neutropenia in Chinese extensive-stage small-cell lung cancer patients.	0.000814326	2014	MDM2	12	68808800	T	G
rs2305482	25515861	3447	IFNA13	umls:C0023530	BeFree	Logistic regression analysis showed that rs2305482 CC and neutrophil count at baseline were independent predictive factors for IFN-induced neutropenia (OR = 2.497, P = 0.0072 and OR = 0.998, P < 0.0001, respectively).	0.000542884	2014	PSMD3	17	39984674	A	C
rs2305482	25515861	3447	IFNA13	umls:C0027947	BeFree	Logistic regression analysis showed that rs2305482 CC and neutrophil count at baseline were independent predictive factors for IFN-induced neutropenia (OR = 2.497, P = 0.0072 and OR = 0.998, P < 0.0001, respectively).	0.000542884	2014	PSMD3	17	39984674	A	C
rs2916733	21799462	79648	MCPH1	umls:C0027947	BeFree	The combined analysis indicated that rs2916733 in microcephalin 1 [combined PFisher min=2.27×10, odds ratio (OR)=2.74 with 95% confidence interval (CI)=1.96-3.83; the nonrisk genotype as reference] was significantly associated with epirubicin-induced leukopenia/neutropenia.	0.000271442	2011	MCPH1	8	6465757	G	A
rs2916733	21799462	79648	MCPH1	umls:C0023530	BeFree	The combined analysis indicated that rs2916733 in microcephalin 1 [combined PFisher min=2.27×10, odds ratio (OR)=2.74 with 95% confidence interval (CI)=1.96-3.83; the nonrisk genotype as reference] was significantly associated with epirubicin-induced leukopenia/neutropenia.	0.000271442	2011	MCPH1	8	6465757	G	A
rs3087403	24956248	51455	REV1	umls:C0027947	BeFree	Polymorphic REV1 rs3087403 allele and REV1 TGT haplotype were associated with increased risk for leukopenia (p = 0.013 and p = 0.047, respectively) and neutropenia (p = 0.048 and p = 0.024, respectively).	0.000271442	2015	REV1	2	99442408	C	T
rs3087403	24956248	51455	REV1	umls:C0023530	BeFree	Polymorphic REV1 rs3087403 allele and REV1 TGT haplotype were associated with increased risk for leukopenia (p = 0.013 and p = 0.047, respectively) and neutropenia (p = 0.048 and p = 0.024, respectively).	0.000271442	2015	REV1	2	99442408	C	T
rs3087403	24956248	81890	QTRT1	umls:C0027947	BeFree	Polymorphic REV1 rs3087403 allele and REV1 TGT haplotype were associated with increased risk for leukopenia (p = 0.013 and p = 0.047, respectively) and neutropenia (p = 0.048 and p = 0.024, respectively).	0.000271442	2015	REV1	2	99442408	C	T
rs3087403	24956248	81890	QTRT1	umls:C0023530	BeFree	Polymorphic REV1 rs3087403 allele and REV1 TGT haplotype were associated with increased risk for leukopenia (p = 0.013 and p = 0.047, respectively) and neutropenia (p = 0.048 and p = 0.024, respectively).	0.000271442	2015	REV1	2	99442408	C	T
rs3136228	22868256	2956	MSH6	umls:C0023530	BeFree	hMSH6-rs3136228 was associated with grade 3-4 neutropenia (3.23(1.38-7.57), q-value=0.0937).	0.000271442	2012	MSH6	2	47782677	T	G
rs3136228	22868256	2956	MSH6	umls:C0027947	BeFree	hMSH6-rs3136228 was associated with grade 3-4 neutropenia (3.23(1.38-7.57), q-value=0.0937).	0.000271442	2012	MSH6	2	47782677	T	G
rs386467430	25381393	1806	DPYD	umls:C0023530	BeFree	The DPYD*2A variant statistically significantly associated with the specific AEs nausea/vomiting (P = .007) and neutropenia (P < .001), whereas D949V statistically significantly associated with dehydration (P = .02), diarrhea (P = .003), leukopenia (P = .002), neutropenia (P < .001), and thrombocytopenia (P < .001).	0.003452799	2015	NA	NA	NA	NA	NA
rs386467430	25381393	1806	DPYD	umls:C0027947	BeFree	The DPYD*2A variant statistically significantly associated with the specific AEs nausea/vomiting (P = .007) and neutropenia (P < .001), whereas D949V statistically significantly associated with dehydration (P = .02), diarrhea (P = .003), leukopenia (P = .002), neutropenia (P < .001), and thrombocytopenia (P < .001).	0.120814326	2015	NA	NA	NA	NA	NA
rs387906717	19006568	7454	WAS	umls:C0023530	BeFree	A large kindred with X-linked neutropenia with an I294T mutation of the Wiskott-Aldrich syndrome gene.	0.001357209	2009	WAS	X	48688403	T	C
rs387906717	19006568	7454	WAS	umls:C0027947	BeFree	A large kindred with X-linked neutropenia with an I294T mutation of the Wiskott-Aldrich syndrome gene.	0.00408156	2009	WAS	X	48688403	T	C
rs4969170	23133602	9021	SOCS3	umls:C0027947	BeFree	HCV treatment-induced neutropenia and thrombocytopenia are associated with SOCS3 rs4969170 polymorphism.	0.000271442	2012	LOC101928674	17	78364457	A	G
rs4969170	23133602	9021	SOCS3	umls:C0023530	BeFree	HCV treatment-induced neutropenia and thrombocytopenia are associated with SOCS3 rs4969170 polymorphism.	0.000271442	2012	LOC101928674	17	78364457	A	G
rs67376798	25381393	1806	DPYD	umls:C0027947	BeFree	The DPYD*2A variant statistically significantly associated with the specific AEs nausea/vomiting (P = .007) and neutropenia (P < .001), whereas D949V statistically significantly associated with dehydration (P = .02), diarrhea (P = .003), leukopenia (P = .002), neutropenia (P < .001), and thrombocytopenia (P < .001).	0.120814326	2015	DPYD	1	97082391	T	A
rs67376798	25381393	1806	DPYD	umls:C0023530	BeFree	The DPYD*2A variant statistically significantly associated with the specific AEs nausea/vomiting (P = .007) and neutropenia (P < .001), whereas D949V statistically significantly associated with dehydration (P = .02), diarrhea (P = .003), leukopenia (P = .002), neutropenia (P < .001), and thrombocytopenia (P < .001).	0.003452799	2015	DPYD	1	97082391	T	A
rs6838440	21799462	80216	ALPK1	umls:C0023530	GAD	[Our findings show that genetic variants in the microcephalin 1 locus are suggestively associated with the risk of epirubicin-induced ADRs and might be applicable in development of diagnostic system for predicting the risk of the ADRs, leading to better pr]	0.002367032	2011	ALPK1	4	112406922	C	T
rs693955	25735499	1635	DCTD	umls:C0027947	BeFree	The DCTD rs9990999 AG/GG and SLC29A1 rs693955 CC genotypes were also significantly associated with shorter duration of neutropenia.	0.000271442	2015	SLC29A1	6	44224183	A	C
rs693955	25735499	2030	SLC29A1	umls:C0027947	BeFree	The DCTD rs9990999 AG/GG and SLC29A1 rs693955 CC genotypes were also significantly associated with shorter duration of neutropenia.	0.000271442	2015	SLC29A1	6	44224183	A	C
rs693955	25735499	1635	DCTD	umls:C0023530	BeFree	The DCTD rs9990999 AG/GG and SLC29A1 rs693955 CC genotypes were also significantly associated with shorter duration of neutropenia.	0.000271442	2015	SLC29A1	6	44224183	A	C
rs693955	25735499	2030	SLC29A1	umls:C0023530	BeFree	The DCTD rs9990999 AG/GG and SLC29A1 rs693955 CC genotypes were also significantly associated with shorter duration of neutropenia.	0.000271442	2015	SLC29A1	6	44224183	A	C
rs9561778	19696793	231	AKR1B1	umls:C0027947	BeFree	Subgroup analysis also indicated that the SNP rs9561778 was significantly associated with two major ADR subgroups; gastrointestinal toxicity and leukopenia/neutropenia (Cochran-Armitage trend's P-value=0.00019 and 0.014; OR=2.31 and 1.83).	0.000271442	2009	ABCC4	13	95061461	G	A,T
rs9561778	19696793	231	AKR1B1	umls:C0023530	BeFree	Subgroup analysis also indicated that the SNP rs9561778 was significantly associated with two major ADR subgroups; gastrointestinal toxicity and leukopenia/neutropenia (Cochran-Armitage trend's P-value=0.00019 and 0.014; OR=2.31 and 1.83).	0.000271442	2009	ABCC4	13	95061461	G	A,T
rs9990999	25735499	1635	DCTD	umls:C0027947	BeFree	The DCTD rs9990999 AG/GG and SLC29A1 rs693955 CC genotypes were also significantly associated with shorter duration of neutropenia.	0.000271442	2015	DCTD	4	182902820	G	A
rs9990999	25735499	2030	SLC29A1	umls:C0023530	BeFree	The DCTD rs9990999 AG/GG and SLC29A1 rs693955 CC genotypes were also significantly associated with shorter duration of neutropenia.	0.000271442	2015	DCTD	4	182902820	G	A
rs9990999	25735499	1635	DCTD	umls:C0023530	BeFree	The DCTD rs9990999 AG/GG and SLC29A1 rs693955 CC genotypes were also significantly associated with shorter duration of neutropenia.	0.000271442	2015	DCTD	4	182902820	G	A
rs9990999	25735499	2030	SLC29A1	umls:C0027947	BeFree	The DCTD rs9990999 AG/GG and SLC29A1 rs693955 CC genotypes were also significantly associated with shorter duration of neutropenia.	0.000271442	2015	DCTD	4	182902820	G	A

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:1458)
CHR	POS	SNPID	REF	ALT	ORI_SNPID	PMID	P_VALUE	P_VALUE_TEXT	OR/BETA	CI95_TEXT	GWAS_INITIAL_SAMPLE_SIZE	SUB_POPULATION	SUPER_POPULATION	GWAS_TRAIT	HPO_ID	HPO_TERM	DO_ID	DO_TERM	MESH_ID	MESH_TERM	EFO_ID	EFO_TERM	DOLITE_TERM	RISK_ALLELE	PUBLICATION_TYPE	AA	GENE_SYMBOL	TYPE	REFGENE
1	1138913	rs3819001	T	C	rs3819001	23648065	5.45E-05	Allelic model	2.78	[1.70-4.53]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs3819001-C	Research Support, Non-U.S. Gov't
1	2068906	rs3128296	G	T	rs3128296	23648065	2.45E-05	Dominant model	10.94	[2.55-46.90]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs3128296-G	Research Support, Non-U.S. Gov't
1	2281726	rs7527871	A	C	rs7527871	23648065	8.70E-05	Recessive model	1.37	[1.15-1.64]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7527871-A	Research Support, Non-U.S. Gov't
1	5142784	rs12047111	A	G	rs12047111	23648065	6.69E-05	Allelic model	2.37	[1.53-3.69]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12047111-G	Research Support, Non-U.S. Gov't
1	5142818	rs2334263	T	C	rs2334263	23648065	4.87E-05	Dominant model	2.06	[1.36-3.12]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2334263-G	Research Support, Non-U.S. Gov't
1	5689702	rs770683	A	G	rs770683	23648065	7.54E-05	Dominant model	2.25	[1.48-3.43]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs770683-T	Research Support, Non-U.S. Gov't
1	9533238	rs6679380	C	T	rs6679380	23648065	8.33E-05	Allelic model	2.58	[1.60-4.15]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6679380-G	Research Support, Non-U.S. Gov't
1	15339960	rs6429703	T	C	rs6429703	23648065	8.00E-06	Allelic model	2.94	[1.80-4.80]	150 Japanese ancestry cases; 166 Japanese ancestry controls	Japanese(316)	ALL(316)	ASN(316)	ALL(316)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6429703-T	Research Support, Non-U.S. Gov't
1	20061456	rs3850533	T	C	rs3850533	23648065	2.40E-05	Dominant model	2.69	[1.34-5.40]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs3850533-C	Research Support, Non-U.S. Gov't
1	20279405	rs818968	C	T	rs818968	23648065	4.76E-05	Allelic model	2.38	[1.51-3.75]	150 Japanese ancestry cases; 166 Japanese ancestry controls	Japanese(316)	ALL(316)	ASN(316)	ALL(316)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs818968-G	Research Support, Non-U.S. Gov't
1	21826566	rs6667242	A	G	rs6667242	23648065	1.11E-05	Dominant model	1.42	[1.19-1.69]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6667242-A	Research Support, Non-U.S. Gov't
1	21837755	rs16825455	A	G	rs16825455	23648065	9.00E-06	Dominant model	1.43	[1.19-1.70]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs16825455-T	Research Support, Non-U.S. Gov't
1	22493672	rs2807356	T	C	rs2807356	23648065	3.59E-05	Allelic model	3.68	[2.04-6.67]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2807356-T	Research Support, Non-U.S. Gov't
1	30278550	rs10914475	C	T	rs10914475	23648065	4.98E-05	Dominant model	6.79	[2.28-20.25]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10914475-A	Research Support, Non-U.S. Gov't
1	30660403	rs7523165	A	G	rs7523165	23648065	7.83E-05	Allelic model	1.81	[1.36-2.42]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7523165-G	Research Support, Non-U.S. Gov't
1	30660839	rs12072928	T	G	rs12072928	23648065	3.99E-05	Allelic model	1.93	[1.42-2.63]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12072928-G	Research Support, Non-U.S. Gov't
1	30663554	rs10915040	A	G	rs10915040	23648065	4.71E-05	Allelic model	1.9	[1.40-2.59]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10915040-G	Research Support, Non-U.S. Gov't
1	31022237	rs904257	A	G	rs904257	23648065	2.71E-05	Recessive model	1.58	[1.13-2.22]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs904257-G	Research Support, Non-U.S. Gov't
1	31034663	rs3104425	C	T	rs3104425	23648065	2.71E-05	Recessive model	1.58	[1.13-2.22]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs3104425-A	Research Support, Non-U.S. Gov't
1	34418942	rs504471	A	G	rs504471	23648065	2.93E-05	Dominant model	2.06	[1.45-2.93]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs504471-G	Research Support, Non-U.S. Gov't
1	38117562	rs4653314	T	C	rs4653314	23648065	1.31E-05	Allelic model	2.88	[1.79-4.62]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4653314-T	Research Support, Non-U.S. Gov't
1	38117562	rs573381957	TC	T	rs4653314	23648065	1.31E-05	Allelic model	2.88	[1.79-4.62]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4653314-T	Research Support, Non-U.S. Gov't
1	41053260	rs6677621	C	T	rs6677621	23648065	9.68E-05	Dominant model	1.73	[1.25-2.40]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6677621-A	Research Support, Non-U.S. Gov't
1	42738366	rs12402117	G	A	rs12402117	23648065	2.71E-05	Dominant model	2.26	[1.45-3.54]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12402117-C	Research Support, Non-U.S. Gov't
1	42738366	rs12402117	G	A	rs12402117	23648065	2.98E-05	Dominant model	4.21	[1.82-9.78]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12402117-C	Research Support, Non-U.S. Gov't
1	44972309	rs781775	G	A	rs781775	23648065	3.82E-05	Allelic model	1.74	[1.34-2.26]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs781775-A	Research Support, Non-U.S. Gov't
1	44974119	rs781770	C	T	rs781770	23648065	2.71E-05	Allelic model	1.77	[1.36-2.29]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs781770-T	Research Support, Non-U.S. Gov't
1	44976806	rs781790	A	G	rs781790	23648065	2.85E-05	Allelic model	1.75	[1.35-2.27]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs781790-C	Research Support, Non-U.S. Gov't
1	46503217	rs1768808	C	T	rs1768808	23648065	1.18E-05	Recessive model	1.44	[1.13-1.84]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1768808-T	Research Support, Non-U.S. Gov't
1	48098406	rs2506991	A	G	rs2506991	23648065	2.00E-06	Recessive model	3.95	[2.10-7.42]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2506991-G	Research Support, Non-U.S. Gov't
1	48100829	rs2506987	A	G	rs2506987	23648065	3.94E-05	Recessive model	3.35	[1.80-6.22]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2506987-C	Research Support, Non-U.S. Gov't
1	48965583	rs12032082	C	T	rs12032082	23648065	6.64E-05	Dominant model	2.69	[1.54-4.69]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12032082-T	Research Support, Non-U.S. Gov't
1	49664304	rs11591141	C	T	rs11591141	23648065	2.26E-05	Recessive model	1.5	[1.12-2.00]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11591141-G	Research Support, Non-U.S. Gov't
1	49762418	rs1431638	C	T	rs1431638	23648065	2.26E-05	Recessive model	1.51	[1.13-2.02]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1431638-G	Research Support, Non-U.S. Gov't
1	49949006	rs1933271	C	T	rs1933271	23648065	2.26E-05	Recessive model	1.56	[1.17-2.10]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1933271-C	Research Support, Non-U.S. Gov't
1	50128198	rs4408195	G	A	rs4408195	23648065	2.26E-05	Recessive model	1.54	[1.15-2.06]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4408195-C	Research Support, Non-U.S. Gov't
1	52293570	rs2077725	G	A	rs2077725	23648065	8.92E-05	Allelic model	2.16	[1.45-3.23]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2077725-A	Research Support, Non-U.S. Gov't
1	52316785	rs6676789	T	C	rs6676789	23648065	8.92E-05	Allelic model	2.16	[1.45-3.23]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6676789-G	Research Support, Non-U.S. Gov't
1	52343297	rs6663305	A	G	rs6663305	23648065	8.98E-05	Allelic model	2.15	[1.44-3.22]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6663305-A	Research Support, Non-U.S. Gov't
1	56429031	rs2192102	C	A	rs2192102	23648065	4.66E-05	Recessive model	1.53	[1.11-2.09]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2192102-A	Research Support, Non-U.S. Gov't
1	56432184	rs12409063	G	A	rs12409063	23648065	4.66E-05	Recessive model	1.53	[1.11-2.09]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12409063-A	Research Support, Non-U.S. Gov't
1	56798308	rs2994565	A	G	rs2994565	23648065	2.25E-05	Recessive model	1.44	[1.04-1.99]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2994565-A	Research Support, Non-U.S. Gov't
1	58857598	rs849492	C	A	rs849492	23648065	9.44E-05	Recessive model	1.33	[1.09-1.63]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs849492-G	Research Support, Non-U.S. Gov't
1	58857666	rs338934	A	G	rs338934	23648065	3.32E-05	Recessive model	1.35	[1.10-1.65]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs338934-T	Research Support, Non-U.S. Gov't
1	66238379	rs12046844	G	A	rs12046844	23648065	5.84E-04	Dominant model	2.53	[1.45-4.43]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12046844-C	Research Support, Non-U.S. Gov't
1	68604773	rs1864570	G	A	rs1864570	23648065	7.32E-05	Dominant model	3.49	[1.61-7.55]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1864570-A	Research Support, Non-U.S. Gov't
1	68633924	rs1367448	G	A	rs1367448	23648065	5.00E-06	Dominant model	1.55	[1.21-1.99]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1367448-C	Research Support, Non-U.S. Gov't
1	69975660	rs10889833	G	A	rs10889833	23648065	2.54E-05	Allelic model	2.15	[1.50-3.08]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10889833-C	Research Support, Non-U.S. Gov't
1	79110518	rs4650590	A	G	rs4650590	23648065	5.21E-05	Dominant model	1.58	[1.19-2.09]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4650590-C	Research Support, Non-U.S. Gov't
1	81996353	rs17454592	G	A	rs17454592	23648065	5.60E-05	Dominant model	3.81	[1.78-8.13]	150 Japanese ancestry cases; 166 Japanese ancestry controls	Japanese(316)	ALL(316)	ASN(316)	ALL(316)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs17454592-C	Research Support, Non-U.S. Gov't
1	82848122	rs11163467	C	T	rs11163467	23648065	5.77E-05	Recessive model	1.35	[1.06-1.71]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11163467-A	Research Support, Non-U.S. Gov't
1	83171994	rs10493722	C	T	rs10493722	23648065	7.46E-05	Allelic model	4.32	[2.10-8.87]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10493722-T	Research Support, Non-U.S. Gov't
1	83204106	rs2060361	C	T	rs2060361	23648065	7.46E-05	Allelic model	4.32	[2.10-8.87]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2060361-A	Research Support, Non-U.S. Gov't
1	85400114	rs1325277	C	A	rs1325277	23648065	5.63E-05	Recessive model	1.23	[1.02-1.49]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1325277-G	Research Support, Non-U.S. Gov't
1	86008398	rs17099679	A	G	rs17099679	23648065	6.63E-05	Allelic model	2.31	[1.51-3.52]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs17099679-A	Research Support, Non-U.S. Gov't
1	86008536	rs12734233	G	A	rs12734233	23648065	6.63E-05	Allelic model	2.31	[1.51-3.52]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12734233-G	Research Support, Non-U.S. Gov't
1	88083782	rs923545	G	A	rs923545	23648065	4.11E-05	Allelic model	2	[1.44-2.77]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs923545-T	Research Support, Non-U.S. Gov't
1	88287371	rs2491281	C	T	rs2491281	23648065	8.45E-05	Dominant model	1.62	[1.27-2.06]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2491281-T	Research Support, Non-U.S. Gov't
1	90005132	rs9428043	T	C	rs9428043	23648065	4.26E-05	Recessive model	1.79	[1.24-2.59]	150 Japanese ancestry cases; 166 Japanese ancestry controls	Japanese(316)	ALL(316)	ASN(316)	ALL(316)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9428043-G	Research Support, Non-U.S. Gov't
1	90005132	rs9428043	T	C	rs9428043	23648065	9.25E-05	Recessive model	1.51	[1.15-1.98]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9428043-G	Research Support, Non-U.S. Gov't
1	90022796	rs922107	A	G	rs922107	23648065	3.00E-06	Recessive model	1.79	[1.25-2.56]	150 Japanese ancestry cases; 166 Japanese ancestry controls	Japanese(316)	ALL(316)	ASN(316)	ALL(316)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs922107-G	Research Support, Non-U.S. Gov't
1	90023768	rs6699344	G	A	rs6699344	23648065	2.02E-05	Recessive model	1.34	[1.01-1.77]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6699344-A	Research Support, Non-U.S. Gov't
1	90023768	rs6699344	G	A	rs6699344	23648065	2.73E-06	Recessive model	1.83	[1.26-2.64]	150 Japanese ancestry cases; 166 Japanese ancestry controls	Japanese(316)	ALL(316)	ASN(316)	ALL(316)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6699344-A	Research Support, Non-U.S. Gov't
1	90023768	rs6699344	G	A	rs6699344	23648065	4.13E-06	Recessive model	1.58	[1.20-2.06]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6699344-A	Research Support, Non-U.S. Gov't
1	90025519	rs922106	C	A	rs922106	23648065	9.00E-07	Recessive model	1.68	[1.28-2.21]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs922106-T	Research Support, Non-U.S. Gov't
1	90032940	rs10922664	A	G	rs10922664	23648065	3.70E-05	Recessive model	1.39	[1.04-1.84]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10922664-G	Research Support, Non-U.S. Gov't
1	90032940	rs10922664	A	G	rs10922664	23648065	5.80E-06	Recessive model	1.87	[1.28-2.71]	150 Japanese ancestry cases; 166 Japanese ancestry controls	Japanese(316)	ALL(316)	ASN(316)	ALL(316)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10922664-G	Research Support, Non-U.S. Gov't
1	90032940	rs10922664	A	G	rs10922664	23648065	9.28E-07	Recessive model	1.68	[1.28-2.21]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10922664-G	Research Support, Non-U.S. Gov't
1	90050831	rs7516314	A	G	rs7516314	23648065	3.70E-05	Recessive model	1.37	[1.03-1.82]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7516314-C	Research Support, Non-U.S. Gov't
1	90050831	rs7516314	A	G	rs7516314	23648065	3.77E-06	Recessive model	1.66	[1.26-2.17]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7516314-C	Research Support, Non-U.S. Gov't
1	90050831	rs7516314	A	G	rs7516314	23648065	5.80E-06	Recessive model	1.87	[1.29-2.72]	150 Japanese ancestry cases; 166 Japanese ancestry controls	Japanese(316)	ALL(316)	ASN(316)	ALL(316)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7516314-C	Research Support, Non-U.S. Gov't
1	90053245	rs12135419	C	T	rs12135419	23648065	3.70E-05	Recessive model	1.37	[1.03-1.82]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12135419-T	Research Support, Non-U.S. Gov't
1	90053245	rs12135419	C	T	rs12135419	23648065	3.77E-06	Recessive model	1.66	[1.26-2.17]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12135419-T	Research Support, Non-U.S. Gov't
1	90053245	rs12135419	C	T	rs12135419	23648065	5.80E-06	Recessive model	1.87	[1.29-2.72]	150 Japanese ancestry cases; 166 Japanese ancestry controls	Japanese(316)	ALL(316)	ASN(316)	ALL(316)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12135419-T	Research Support, Non-U.S. Gov't
1	97992257	rs2811173	C	T	rs2811173	23648065	9.01E-05	Dominant model	2.95	[1.59-5.49]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2811173-G	Research Support, Non-U.S. Gov't
1	99184798	rs12725220	G	A	rs12725220	23648065	3.08E-05	Allelic model	1.72	[1.33-2.22]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12725220-C	Research Support, Non-U.S. Gov't
1	99515902	rs7530449	T	G	rs7530449	23648065	7.66E-05	Dominant model	2.23	[1.44-3.48]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7530449-G	Research Support, Non-U.S. Gov't
1	99533944	rs17119481	A	C	rs17119481	23648065	7.66E-05	Dominant model	2.18	[1.40-3.38]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs17119481-C	Research Support, Non-U.S. Gov't
1	99589379	rs303386	C	T	rs303386	23648065	4.00E-06	Dominant	1.77	[1.26-2.48]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs303386-A	Research Support, Non-U.S. Gov't
1	99589379	rs303386	C	T	rs303386	23648065	4.00E-06	Dominant model	2.24	[1.45-3.46]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs303386-A	Research Support, Non-U.S. Gov't
1	105688179	rs11184448	A	G	rs11184448	23648065	7.78E-05	Dominant model	1.4	[1.15-1.69]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11184448-A	Research Support, Non-U.S. Gov't
1	105688537	rs17015466	G	A	rs17015466	23648065	7.78E-05	Dominant model	1.4	[1.15-1.69]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs17015466-G	Research Support, Non-U.S. Gov't
1	105725458	rs6667576	C	T	rs6667576	23648065	7.86E-05	Allelic model	1.88	[1.36-2.60]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6667576-G	Research Support, Non-U.S. Gov't
1	108302922	rs12142335	G	A	rs12142335	23648065	8.00E-06	Dominant model	9.71	[3.17-29.71]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12142335-A	Research Support, Non-U.S. Gov't
1	108315137	rs4462178	C	T	rs4462178	23648065	8.45E-06	Dominant model	9.71	[3.17-29.71]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4462178-T	Research Support, Non-U.S. Gov't
1	109392837	rs1277203	C	T	rs1277203	23648065	9.00E-06	Recessive model	1.62	[1.24-2.10]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1277203-A	Research Support, Non-U.S. Gov't
1	109783555	rs4246519	A	G	rs4246519	23648065	1.60E-05	Allelic model	1.7	[1.34-2.15]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4246519-A	Research Support, Non-U.S. Gov't
1	109784781	rs586254	A	G	rs586254	23648065	4.76E-05	Allelic model	1.65	[1.30-2.10]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs586254-C	Research Support, Non-U.S. Gov't
1	111087124	rs2790372	C	A	rs2790372	23648065	7.52E-05	Dominant model	3.06	[1.60-5.88]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2790372-C	Research Support, Non-U.S. Gov't
1	111089405	rs1625029	C	T	rs1625029	23648065	7.52E-05	Dominant model	3.06	[1.60-5.88]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1625029-G	Research Support, Non-U.S. Gov't
1	111100562	rs6537668	T	C	rs6537668	23648065	4.12E-05	Allelic model	1.79	[1.35-2.39]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6537668-A	Research Support, Non-U.S. Gov't
1	115774074	rs971723	A	C	rs971723	23648065	9.08E-05	Recessive model	1.54	[1.10-2.16]	150 Japanese ancestry cases; 166 Japanese ancestry controls	Japanese(316)	ALL(316)	ASN(316)	ALL(316)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs971723-A	Research Support, Non-U.S. Gov't
1	115782754	rs7542599	T	C	rs7542599	23648065	8.83E-05	Recessive model	1.51	[1.08-2.12]	150 Japanese ancestry cases; 166 Japanese ancestry controls	Japanese(316)	ALL(316)	ASN(316)	ALL(316)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7542599-T	Research Support, Non-U.S. Gov't
1	117367190	rs6428670	T	C	rs6428670	23648065	2.76E-05	Recessive model	1.39	[1.07-1.81]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6428670-G	Research Support, Non-U.S. Gov't
1	151673350	rs1308145	T	C	rs1308145	23648065	9.31E-05	Recessive model	1.57	[1.22-2.02]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1308145-G	Research Support, Non-U.S. Gov't
1	151679441	rs1308152	T	C	rs1308152	23648065	1.83E-05	Recessive model	2.05	[1.42-2.97]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1308152-C	Research Support, Non-U.S. Gov't
1	151679441	rs1308152	T	C	rs1308152	23648065	3.79E-05	Recessive model	1.66	[1.28-2.15]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1308152-C	Research Support, Non-U.S. Gov't
1	151684262	rs3762302	T	C	rs3762302	23648065	3.34E-05	Dominant model	1.7	[1.20-2.41]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs3762302-C	Research Support, Non-U.S. Gov't
1	151778683	rs9017	C	T	rs9017	23648065	7.80E-05	Recessive model	1.5	[1.16-1.94]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9017-G	Research Support, Non-U.S. Gov't
1	154340789	rs12025518	A	C	rs12025518	23648065	6.26E-05	Allelic model	7.23	[2.41-21.73]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12025518-T	Research Support, Non-U.S. Gov't
1	159582103	rs10494331	C	T	rs10494331	23648065	2.52E-05	Allelic model	2.76	[1.72-4.44]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10494331-G	Research Support, Non-U.S. Gov't
1	159582218	rs4233355	G	A	rs4233355	23648065	3.53E-05	Allelic model	2.77	[1.71-4.47]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4233355-T	Research Support, Non-U.S. Gov't
1	167803823	rs3752608	G	T	rs3752608	23648065	7.27E-05	Allelic model	3.7	[1.98-6.92]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs3752608-T	Research Support, Non-U.S. Gov't
1	170856852	rs10489239	C	T	rs10489239	23648065	3.83E-05	Dominant model	1.51	[1.18-1.92]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10489239-G	Research Support, Non-U.S. Gov't
1	170858095	rs10489241	T	C	rs10489241	23648065	3.83E-05	Dominant model	1.5	[1.17-1.91]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10489241-A	Research Support, Non-U.S. Gov't
1	170860531	rs12038181	C	T	rs12038181	23648065	3.83E-05	Dominant model	1.5	[1.17-1.91]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12038181-G	Research Support, Non-U.S. Gov't
1	174246712	rs6670617	C	A	rs6670617	23648065	8.65E-05	Recessive model	1.54	[1.22-1.94]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6670617-T	Research Support, Non-U.S. Gov't
1	174258877	rs4650989	G	A	rs4650989	23648065	3.68E-05	Recessive model	1.55	[1.23-1.96]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4650989-T	Research Support, Non-U.S. Gov't
1	174266642	rs7555067	C	T	rs7555067	23648065	8.61E-05	Recessive model	1.55	[1.23-1.96]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7555067-T	Research Support, Non-U.S. Gov't
1	174312813	rs17301013	C	T	rs17301013	23648065	5.19E-05	Recessive model	1.59	[1.26-2.01]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs17301013-A	Research Support, Non-U.S. Gov't
1	174497642	rs12088073	A	C	rs12088073	23648065	5.18E-05	Recessive model	1.47	[1.17-1.86]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12088073-G	Research Support, Non-U.S. Gov't
1	174499977	rs6425284	G	A	rs6425284	23648065	3.62E-05	Recessive model	1.49	[1.18-1.88]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6425284-T	Research Support, Non-U.S. Gov't
1	174499977	rs6425284	G	A	rs6425284	23648065	7.79E-05	Recessive model	1.62	[1.24-2.12]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6425284-T	Research Support, Non-U.S. Gov't
1	174592050	rs6664864	A	G	rs6664864	23648065	2.56E-05	Recessive model	1.52	[1.20-1.91]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6664864-C	Research Support, Non-U.S. Gov't
1	174818547	rs3018410	A	G	rs3018410	23648065	3.61E-05	Recessive model	1.52	[1.20-1.92]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs3018410-T	Research Support, Non-U.S. Gov't
1	175391741	rs6666777	C	T	rs6666777	23648065	7.53E-05	Recessive model	1.67	[1.17-2.40]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6666777-G	Research Support, Non-U.S. Gov't
1	177271313	rs16851037	G	A	rs16851037	23648065	7.63E-05	Recessive model	1.21	[0.92-1.60]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs16851037-T	Research Support, Non-U.S. Gov't
1	182420448	rs267866	G	A	rs267866	23648065	6.03E-05	Allelic model	3.18	[1.73-5.85]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs267866-T	Research Support, Non-U.S. Gov't
1	185341597	rs4651254	T	C	rs4651254	23648065	6.18E-05	Allelic model	1.43	[1.20-1.71]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4651254-G	Research Support, Non-U.S. Gov't
1	185347488	rs10911713	C	T	rs10911713	23648065	8.31E-05	Allelic model	1.45	[1.21-1.75]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10911713-T	Research Support, Non-U.S. Gov't
1	186163076	rs1322375	T	C	rs1322375	23648065	3.78E-05	Allelic model	2.42	[1.61-3.66]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1322375-C	Research Support, Non-U.S. Gov't
1	186172443	rs1885522	C	A	rs1885522	23648065	4.02E-05	Allelic model	2.38	[1.60-3.54]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1885522-A	Research Support, Non-U.S. Gov't
1	192940642	rs12025826	G	A	rs12025826	23648065	7.57E-05	Dominant model	1.75	[1.23-2.47]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12025826-G	Research Support, Non-U.S. Gov't
1	194591753	rs13376197	T	C	rs13376197	23648065	6.69E-05	Dominant model	5.69	[2.36-13.70]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs13376197-C	Research Support, Non-U.S. Gov't
1	194910364	rs6695766	G	A	rs6695766	23648065	4.20E-05	Allelic model	2.92	[1.68-5.08]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6695766-C	Research Support, Non-U.S. Gov't
1	194965856	rs11583374	T	C	rs11583374	23648065	9.68E-05	Allelic model	2.64	[1.56-4.46]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11583374-T	Research Support, Non-U.S. Gov't
1	195367222	rs1987929	T	C	rs1987929	23648065	9.62E-05	Allelic model	2.4	[1.53-3.74]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1987929-G	Research Support, Non-U.S. Gov't
1	198469162	rs10922438	G	A	rs10922438	23648065	6.00E-06	Allelic model	2.3	[1.61-3.29]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10922438-T	Research Support, Non-U.S. Gov't
1	198481371	rs12058080	C	T	rs12058080	23648065	6.01E-06	Allelic model	2.3	[1.61-3.29]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12058080-T	Research Support, Non-U.S. Gov't
1	198484209	rs2359847	C	T	rs2359847	23648065	6.01E-06	Allelic model	2.3	[1.61-3.29]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2359847-T	Research Support, Non-U.S. Gov't
1	198484784	rs16843226	A	G	rs16843226	23648065	6.01E-06	Allelic model	2.3	[1.61-3.29]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs16843226-C	Research Support, Non-U.S. Gov't
1	198485706	rs12083381	T	C	rs12083381	23648065	6.01E-06	Allelic model	2.3	[1.61-3.29]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12083381-C	Research Support, Non-U.S. Gov't
1	198489457	rs10494777	T	C	rs10494777	23648065	6.01E-06	Allelic model	2.3	[1.61-3.29]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10494777-C	Research Support, Non-U.S. Gov't
1	198494473	rs10922446	C	T	rs10922446	23648065	6.01E-06	Allelic model	2.3	[1.61-3.29]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10922446-A	Research Support, Non-U.S. Gov't
1	201101413	rs6697303	C	T	rs6697303	23648065	3.81E-05	Dominant model	2.54	[1.54-4.20]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6697303-T	Research Support, Non-U.S. Gov't
1	201429381	rs12090950	G	A	rs12090950	23648065	1.76E-05	Allelic model	2.18	[1.54-3.08]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12090950-T	Research Support, Non-U.S. Gov't
1	201429381	rs12090950	G	A	rs12090950	23648065	4.64E-05	Allelic model	2.45	[1.62-3.70]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12090950-T	Research Support, Non-U.S. Gov't
1	201775746	rs4379719	G	A	rs4379719	23648065	2.45E-05	Dominant model	2.44	[1.57-3.78]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4379719-C	Research Support, Non-U.S. Gov't
1	204006104	rs4951290	T	G	rs4951290	23648065	8.52E-05	Dominant model	2.82	[1.64-4.85]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4951290-C	Research Support, Non-U.S. Gov't
1	206714818	rs9661909	C	T	rs9661909	23648065	2.07E-05	Recessive model	1.7	[1.15-2.51]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9661909-C	Research Support, Non-U.S. Gov't
1	207143422	rs1856746	A	G	rs1856746	23648065	8.46E-05	Allelic model	1.67	[1.29-2.16]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1856746-T	Research Support, Non-U.S. Gov't
1	207162433	rs2791708	T	C	rs2791708	23648065	7.67E-05	Allelic model	1.69	[1.30-2.19]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2791708-T	Research Support, Non-U.S. Gov't
1	208578200	rs710417	G	A	rs710417	23648065	7.72E-05	Recessive model	1.64	[1.17-2.31]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs710417-T	Research Support, Non-U.S. Gov't
1	209581483	rs1988163	C	A	rs1988163	23648065	3.12E-05	Dominant model	1.88	[1.29-2.73]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1988163-G	Research Support, Non-U.S. Gov't
1	211666218	rs10863899	A	G	rs10863899	23648065	2.50E-05	Recessive model	1.22	[0.91-1.66]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10863899-A	Research Support, Non-U.S. Gov't
1	211672506	rs755448	G	A	rs755448	23648065	2.37E-05	Recessive model	1.24	[0.90-1.71]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs755448-G	Research Support, Non-U.S. Gov't
1	212757658	rs4543871	T	C	rs4543871	23648065	2.54E-05	Allelic model	2.48	[1.63-3.78]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4543871-G	Research Support, Non-U.S. Gov't
1	212757658	rs4543871	T	C	rs4543871	23648065	5.17E-05	Allelic model	2.19	[1.51-3.17]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4543871-G	Research Support, Non-U.S. Gov't
1	213120103	rs6656706	C	T	rs6656706	23648065	9.07E-05	Allelic model	1.74	[1.31-2.30]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6656706-C	Research Support, Non-U.S. Gov't
1	216705965	rs6696225	T	C	rs6696225	23648065	1.34E-05	Recessive model	1.28	[1.07-1.54]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6696225-C	Research Support, Non-U.S. Gov't
1	216707012	rs1833036	G	T	rs1833036	23648065	1.46E-05	Recessive model	1.28	[1.06-1.54]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1833036-A	Research Support, Non-U.S. Gov't
1	216715514	rs2377098	G	T	rs2377098	23648065	3.33E-06	Recessive model	1.33	[1.10-1.61]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2377098-T	Research Support, Non-U.S. Gov't
1	216716320	rs12145418	G	T	rs12145418	23648065	2.00E-06	Recessive model	1.33	[1.10-1.60]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12145418-T	Research Support, Non-U.S. Gov't
1	216726333	rs10442688	T	C	rs10442688	23648065	6.60E-06	Recessive model	1.3	[1.08-1.57]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10442688-G	Research Support, Non-U.S. Gov't
1	216727323	rs4846528	C	T	rs4846528	23648065	3.43E-05	Recessive model	1.28	[1.06-1.54]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4846528-A	Research Support, Non-U.S. Gov't
1	216966601	rs7355008	T	C	rs7355008	23648065	9.82E-05	Allelic model	1.46	[1.21-1.77]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7355008-C	Research Support, Non-U.S. Gov't
1	218128141	rs17691163	G	A	rs17691163	23648065	3.88E-05	Allelic model	4.21	[2.13-8.35]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs17691163-T	Research Support, Non-U.S. Gov't
1	218439928	rs1338445	T	C	rs1338445	23648065	2.81E-05	Recessive model	1.91	[1.24-2.94]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1338445-G	Research Support, Non-U.S. Gov't
1	219176608	rs7540160	A	G	rs7540160	23648065	9.91E-05	Recessive model	1.55	[1.19-2.02]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7540160-T	Research Support, Non-U.S. Gov't
1	225508712	rs648011	C	T	rs648011	23648065	8.52E-05	Recessive model	1.58	[1.13-2.21]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs648011-A	Research Support, Non-U.S. Gov't
1	231922845	rs11590192	T	C	rs11590192	23648065	8.22E-05	Dominant model	1.9	[1.36-2.67]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11590192-G	Research Support, Non-U.S. Gov't
1	234701910	rs9970996	G	A	rs9970996	23648065	9.51E-05	Recessive model	1.25	[0.94-1.66]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9970996-C	Research Support, Non-U.S. Gov't
1	234769793	rs9803801	C	T	rs9803801	23648065	5.14E-05	Dominant model	4.63	[1.97-10.87]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9803801-G	Research Support, Non-U.S. Gov't
1	240091765	rs6666471	G	A	rs6666471	23648065	5.15E-05	Recessive model	1.36	[1.15-1.61]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6666471-C	Research Support, Non-U.S. Gov't
1	244508697	rs4658624	A	G	rs4658624	23648065	4.97E-05	Allelic model	1.68	[1.31-2.16]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4658624-A	Research Support, Non-U.S. Gov't
1	248519821	rs1538703	T	G	rs1538703	23648065	2.98E-05	Dominant model	2.44	[1.42-4.22]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1538703-G	Research Support, Non-U.S. Gov't
1	248521032	rs946761	T	C	rs946761	23648065	6.73E-05	Dominant model	2.4	[1.41-4.11]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs946761-C	Research Support, Non-U.S. Gov't
2	773278	rs4380275	C	T	rs4380275	23648065	5.00E-06	Recessive model	3.6	[2.04-6.37]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4380275-G	Research Support, Non-U.S. Gov't
2	2764201	rs1031348	C	A	rs1031348	23648065	2.42E-05	Dominant model	1.7	[1.29-2.23]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1031348-G	Research Support, Non-U.S. Gov't
2	2978905	rs17437842	C	T	rs17437842	23648065	8.24E-05	Dominant model	1.82	[1.32-2.50]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs17437842-G	Research Support, Non-U.S. Gov't
2	5891097	rs13391560	A	G	rs13391560	23648065	6.64E-05	Allelic model	3.51	[1.89-6.52]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs13391560-A	Research Support, Non-U.S. Gov't
2	9988348	rs1469544	T	G	rs1469544	23648065	5.98E-05	Dominant model	1.6	[1.23-2.08]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1469544-T	Research Support, Non-U.S. Gov't
2	9989442	rs16867195	A	G	rs16867195	23648065	6.07E-05	Dominant model	1.6	[1.23-2.08]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs16867195-A	Research Support, Non-U.S. Gov't
2	9996156	rs1014509	T	C	rs1014509	23648065	5.87E-05	Dominant model	1.61	[1.24-2.09]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1014509-A	Research Support, Non-U.S. Gov't
2	14881995	rs7607607	A	C	rs7607607	23648065	8.96E-05	Recessive model	1.31	[0.90-1.90]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7607607-A	Research Support, Non-U.S. Gov't
2	18314546	rs12471785	G	A	rs12471785	23648065	7.04E-05	Dominant model	1.53	[1.20-1.96]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12471785-G	Research Support, Non-U.S. Gov't
2	20335709	rs4666360	G	A	rs4666360	23648065	3.00E-06	Dominant model	2.14	[1.55-2.95]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4666360-C	Research Support, Non-U.S. Gov't
2	20346651	rs981396	G	A	rs981396	23648065	4.72E-05	Allelic model	2.02	[1.44-2.83]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs981396-T	Research Support, Non-U.S. Gov't
2	23300822	rs1446875	T	C	rs1446875	23648065	2.85E-05	Recessive model	1.59	[1.13-2.23]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1446875-C	Research Support, Non-U.S. Gov't
2	25038268	rs2082881	G	A	rs2082881	23648065	3.72E-05	Dominant model	2.54	[1.57-4.13]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2082881-C	Research Support, Non-U.S. Gov't
2	25041620	rs1550115	C	T	rs1550115	23648065	3.72E-05	Dominant model	2.54	[1.57-4.13]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1550115-C	Research Support, Non-U.S. Gov't
2	25482970	rs11694842	A	G	rs11694842	23648065	4.19E-05	Dominant model	2.12	[1.49-3.03]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11694842-C	Research Support, Non-U.S. Gov't
2	32444054	rs212701	T	C	rs212701	23648065	2.43E-05	Recessive model	1.54	[1.20-1.96]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs212701-G	Research Support, Non-U.S. Gov't
2	32447718	rs177083	C	T	rs177083	23648065	2.43E-05	Recessive model	1.56	[1.22-1.99]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs177083-T	Research Support, Non-U.S. Gov't
2	32450348	rs212704	C	T	rs212704	23648065	3.20E-05	Recessive model	1.58	[1.23-2.02]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs212704-A	Research Support, Non-U.S. Gov't
2	32475109	rs455060	G	A	rs455060	23648065	2.43E-05	Recessive model	1.58	[1.24-2.02]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs455060-A	Research Support, Non-U.S. Gov't
2	34499749	rs6719309	A	C	rs6719309	23648065	2.08E-05	Allelic model	1.8	[1.37-2.37]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6719309-T	Research Support, Non-U.S. Gov't
2	34542730	rs6721933	G	T	rs6721933	23648065	9.65E-05	Recessive model	1.59	[1.21-2.08]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6721933-T	Research Support, Non-U.S. Gov't
2	36625388	rs3770935	C	T	rs3770935	23648065	4.67E-05	Recessive model	1.69	[1.26-2.28]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs3770935-A	Research Support, Non-U.S. Gov't
2	36627725	rs4670145	A	G	rs4670145	23648065	8.74E-05	Recessive model	1.62	[1.20-2.18]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4670145-C	Research Support, Non-U.S. Gov't
2	38178362	rs2197561	T	C	rs2197561	23648065	9.89E-05	Dominant model	1.28	[1.08-1.52]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2197561-G	Research Support, Non-U.S. Gov't
2	40354688	rs2110927	C	T	rs2110927	23648065	5.34E-05	Allelic model	2.75	[1.65-4.61]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2110927-T	Research Support, Non-U.S. Gov't
2	40357323	rs2160364	T	C	rs2160364	23648065	9.64E-05	Allelic model	2.61	[1.58-4.34]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2160364-A	Research Support, Non-U.S. Gov't
2	40358175	rs765554	G	A	rs765554	23648065	2.87E-05	Allelic model	1.96	[1.43-2.68]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs765554-C	Research Support, Non-U.S. Gov't
2	40363644	rs2110922	C	A	rs2110922	23648065	9.03E-05	Allelic model	1.82	[1.35-2.47]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2110922-T	Research Support, Non-U.S. Gov't
2	40376453	rs2058693	T	G	rs2058693	23648065	8.81E-05	Allelic model	1.87	[1.37-2.55]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2058693-G	Research Support, Non-U.S. Gov't
2	40381369	rs13425134	A	G	rs13425134	23648065	9.20E-05	Allelic model	2.47	[1.54-3.96]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs13425134-G	Research Support, Non-U.S. Gov't
2	40384733	rs452369	C	T	rs452369	23648065	9.20E-05	Allelic model	2.47	[1.54-3.96]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs452369-G	Research Support, Non-U.S. Gov't
2	41036518	rs6722048	G	A	rs6722048	23648065	7.99E-05	Recessive model	1.48	[1.08-2.03]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6722048-A	Research Support, Non-U.S. Gov't
2	41273631	rs17027130	T	C	rs17027130	23648065	3.00E-06	Allelic model	2.87	[1.84-4.45]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs17027130-C	Research Support, Non-U.S. Gov't
2	42015775	rs6704827	T	G	rs6704827	23648065	7.74E-05	Dominant model	1.56	[1.20-2.04]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6704827-A	Research Support, Non-U.S. Gov't
2	44554724	rs4953085	A	G	rs4953085	23648065	8.42E-05	Allelic model	1.72	[1.32-2.25]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4953085-G	Research Support, Non-U.S. Gov't
2	45506771	rs12476712	C	T	rs12476712	23648065	3.83E-05	Allelic model	4.01	[2.06-7.81]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12476712-G	Research Support, Non-U.S. Gov't
2	47372425	rs726117	G	A	rs726117	23648065	7.41E-05	Allelic model	1.76	[1.33-2.33]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs726117-A	Research Support, Non-U.S. Gov't
2	49715021	rs12987465	G	A	rs12987465	23648065	7.00E-06	Recessive model	2.6	[1.42-4.74]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12987465-A	Research Support, Non-U.S. Gov't
2	49732935	rs1553127	T	C	rs1553127	23648065	1.85E-05	Dominant model	1.88	[1.40-2.52]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1553127-T	Research Support, Non-U.S. Gov't
2	49732935	rs1553127	T	C	rs1553127	23648065	5.80E-05	Dominant model	1.93	[1.40-2.67]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1553127-T	Research Support, Non-U.S. Gov't
2	49737819	rs1405965	A	G	rs1405965	23648065	2.27E-05	Dominant model	1.95	[1.42-2.67]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1405965-T	Research Support, Non-U.S. Gov't
2	49737819	rs1405965	A	G	rs1405965	23648065	3.87E-05	Dominant model	1.78	[1.34-2.37]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1405965-T	Research Support, Non-U.S. Gov't
2	49749038	rs6709183	C	T	rs6709183	23648065	7.52E-05	Dominant model	1.7	[1.27-2.27]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6709183-A	Research Support, Non-U.S. Gov't
2	49752589	rs4971621	T	C	rs4971621	23648065	6.76E-05	Recessive model	2.6	[1.42-4.74]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4971621-A	Research Support, Non-U.S. Gov't
2	49852392	rs1391749	A	C	rs1391749	23648065	2.26E-05	Allelic model	2.27	[1.56-3.30]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1391749-C	Research Support, Non-U.S. Gov't
2	56656894	rs1861776	A	G	rs1861776	23648065	1.84E-05	Allelic model	2.3	[1.56-3.39]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1861776-G	Research Support, Non-U.S. Gov't
2	56682547	rs13397156	C	A	rs13397156	23648065	2.64E-05	Allelic model	2.29	[1.55-3.38]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs13397156-A	Research Support, Non-U.S. Gov't
2	57147590	rs7589657	C	T	rs7589657	23648065	4.24E-05	Dominant model	1.52	[1.21-1.90]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7589657-A	Research Support, Non-U.S. Gov't
2	57174489	rs7578236	C	T	rs7578236	23648065	8.15E-05	Allelic model	1.42	[1.19-1.68]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7578236-T	Research Support, Non-U.S. Gov't
2	57174489	rs7578236	C	T	rs7578236	23648065	8.58E-05	Allelic model	1.59	[1.26-1.99]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7578236-T	Research Support, Non-U.S. Gov't
2	57436631	rs7604249	T	C	rs7604249	23648065	9.01E-05	Allelic model	1.43	[1.19-1.71]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7604249-G	Research Support, Non-U.S. Gov't
2	57696957	rs17048844	T	C	rs17048844	23648065	4.53E-05	Recessive model	1.79	[1.24-2.58]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs17048844-G	Research Support, Non-U.S. Gov't
2	57696957	rs17048844	T	C	rs17048844	23648065	7.02E-05	Allelic model	1.43	[1.20-1.70]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs17048844-G	Research Support, Non-U.S. Gov't
2	63815801	rs2278718	A	C	rs2278718	23648065	7.51E-05	Recessive model	1.37	[1.11-1.69]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2278718-C	Research Support, Non-U.S. Gov't
2	75186337	rs2287102	A	G	rs2287102	23648065	1.93E-05	Dominant model	1.53	[1.23-1.90]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2287102-A	Research Support, Non-U.S. Gov't
2	75290700	rs13404785	A	G	rs13404785	23648065	5.86E-05	Dominant model	1.41	[1.17-1.69]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs13404785-T	Research Support, Non-U.S. Gov't
2	75291510	rs3755457	G	A	rs3755457	23648065	9.76E-05	Dominant model	1.4	[1.17-1.69]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs3755457-G	Research Support, Non-U.S. Gov't
2	80185885	rs747921	A	G	rs747921	23648065	6.38E-05	Dominant model	2.59	[1.42-4.72]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs747921-A	Research Support, Non-U.S. Gov't
2	80228740	rs1368909	T	C	rs1368909	23648065	1.26E-05	Dominant model	1.85	[1.34-2.53]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1368909-G	Research Support, Non-U.S. Gov't
2	106310212	rs11884955	T	C	rs11884955	23648065	5.96E-05	Recessive model	1.21	[0.92-1.60]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11884955-G	Research Support, Non-U.S. Gov't
2	111740221	rs11123271	A	G	rs11123271	23648065	6.82E-05	Allelic model	1.66	[1.30-2.13]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11123271-G	Research Support, Non-U.S. Gov't
2	111753228	rs6542248	C	A	rs6542248	23648065	2.32E-05	Allelic model	1.74	[1.35-2.25]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6542248-G	Research Support, Non-U.S. Gov't
2	111787027	rs1561476	C	T	rs1561476	23648065	3.95E-05	Allelic model	1.72	[1.33-2.23]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1561476-G	Research Support, Non-U.S. Gov't
2	114637231	rs6720853	C	T	rs6720853	23648065	5.31E-05	Dominant model	2.36	[1.47-3.80]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6720853-T	Research Support, Non-U.S. Gov't
2	114672304	rs12618683	A	G	rs12618683	23648065	5.31E-05	Dominant model	2.28	[1.42-3.66]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12618683-G	Research Support, Non-U.S. Gov't
2	122936737	rs1432312	T	C	rs1432312	23648065	7.82E-05	Allelic model	1.78	[1.33-2.39]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1432312-T	Research Support, Non-U.S. Gov't
2	125061838	rs733112	C	A	rs733112	23648065	1.09E-05	Dominant model	2.06	[1.43-2.98]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs733112-T	Research Support, Non-U.S. Gov't
2	129457798	rs10928827	A	G	rs10928827	23648065	8.59E-05	Dominant model	1.67	[1.21-2.28]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10928827-A	Research Support, Non-U.S. Gov't
2	130024589	rs837898	A	G	rs837898	23648065	9.33E-06	Recessive model	1.28	[0.93-1.76]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs837898-G	Research Support, Non-U.S. Gov't
2	130034012	rs837841	C	A	rs837841	23648065	8.00E-06	Recessive model	1.28	[0.93-1.76]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs837841-T	Research Support, Non-U.S. Gov't
2	133471789	rs10166009	C	T	rs10166009	23648065	3.46E-05	Dominant model	1.99	[1.35-2.93]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10166009-G	Research Support, Non-U.S. Gov't
2	134442532	rs6430443	A	G	rs6430443	23648065	8.61E-04	Recessive model	6.33	[1.90-22.22]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6430443-G	Research Support, Non-U.S. Gov't
2	143746849	rs1050950	C	A	rs1050950	23648065	7.18E-05	Dominant model	1.22	[1.03-1.45]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1050950-T	Research Support, Non-U.S. Gov't
2	143749073	rs1371514	G	A	rs1371514	23648065	7.18E-05	Dominant model	1.22	[1.03-1.45]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1371514-T	Research Support, Non-U.S. Gov't
2	143751071	rs12466715	A	G	rs12466715	23648065	9.24E-05	Dominant model	1.22	[1.03-1.44]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12466715-G	Research Support, Non-U.S. Gov't
2	143931505	rs354696	G	A	rs354696	23648065	4.29E-05	Allelic model	3.74	[1.97-7.10]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs354696-C	Research Support, Non-U.S. Gov't
2	148305357	rs16827511	C	A	rs16827511	23648065	1.36E-05	Dominant model	3.94	[1.97-7.86]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs16827511-C	Research Support, Non-U.S. Gov't
2	148318521	rs12464146	T	C	rs12464146	23648065	1.36E-05	Dominant model	3.94	[1.97-7.86]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12464146-T	Research Support, Non-U.S. Gov't
2	148318521	rs12464146	T	C	rs12464146	23648065	2.44E-05	Dominant model	6.01	[2.13-17.00]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12464146-T	Research Support, Non-U.S. Gov't
2	151345113	rs2222760	G	A	rs2222760	23648065	5.37E-05	Recessive model	1.29	[0.92-1.80]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2222760-T	Research Support, Non-U.S. Gov't
2	155652357	rs1037091	C	T	rs1037091	23648065	9.76E-05	Dominant model	1.49	[1.19-1.87]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1037091-T	Research Support, Non-U.S. Gov't
2	161118687	rs10170600	T	C	rs10170600	23648065	8.38E-05	Dominant model	2.15	[1.38-3.34]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10170600-T	Research Support, Non-U.S. Gov't
2	161133471	rs3772070	T	C	rs3772070	23648065	3.20E-05	Dominant model	2.31	[1.47-3.64]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs3772070-T	Research Support, Non-U.S. Gov't
2	161166234	rs4077463	A	G	rs4077463	23648065	6.55E-05	Dominant model	2.53	[1.57-4.07]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4077463-A	Research Support, Non-U.S. Gov't
2	161192070	rs4410242	A	G	rs4410242	23648065	6.55E-05	Dominant model	2.53	[1.57-4.07]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4410242-A	Research Support, Non-U.S. Gov't
2	161214175	rs6718526	T	C	rs6718526	23648065	2.02E-05	Dominant model	2.81	[1.71-4.63]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6718526-A	Research Support, Non-U.S. Gov't
2	168772522	rs836664	A	G	rs836664	23648065	1.51E-05	Allelic model	2.15	[1.50-3.08]	150 Japanese ancestry cases; 166 Japanese ancestry controls	Japanese(316)	ALL(316)	ASN(316)	ALL(316)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs836664-A	Research Support, Non-U.S. Gov't
2	168775061	rs7576460	C	A	rs7576460	23648065	1.51E-05	Allelic model	2.15	[1.50-3.08]	150 Japanese ancestry cases; 166 Japanese ancestry controls	Japanese(316)	ALL(316)	ASN(316)	ALL(316)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7576460-C	Research Support, Non-U.S. Gov't
2	175893333	rs1150186	T	C	rs1150186	23648065	3.08E-05	Recessive model	1.3	[1.05-1.60]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1150186-T	Research Support, Non-U.S. Gov't
2	188482933	rs7561970	A	G	rs7561970	23648065	2.74E-05	Allelic model	1.54	[1.26-1.89]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7561970-C	Research Support, Non-U.S. Gov't
2	188684507	rs4471853	A	G	rs4471853	23648065	7.21E-05	Dominant model	1.85	[1.33-2.57]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4471853-C	Research Support, Non-U.S. Gov't
2	192465598	rs6706693	C	T	rs6706693	23648065	9.00E-06	Recessive model	1.74	[1.36-2.23]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6706693-A	Research Support, Non-U.S. Gov't
2	192469816	rs4134381	G	A	rs4134381	23648065	2.13E-05	Allelic model	1.73	[1.35-2.22]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4134381-T	Research Support, Non-U.S. Gov't
2	192470385	rs4318338	C	T	rs4318338	23648065	2.86E-05	Allelic model	1.73	[1.35-2.21]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4318338-G	Research Support, Non-U.S. Gov't
2	192473543	rs4853629	C	T	rs4853629	23648065	4.92E-05	Allelic model	1.68	[1.31-2.15]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4853629-A	Research Support, Non-U.S. Gov't
2	192479007	rs3935827	A	G	rs3935827	23648065	4.35E-05	Allelic model	1.7	[1.33-2.18]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs3935827-T	Research Support, Non-U.S. Gov't
2	192479674	rs4401164	A	G	rs4401164	23648065	4.37E-05	Allelic model	1.7	[1.33-2.17]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4401164-T	Research Support, Non-U.S. Gov't
2	192490640	rs11899661	A	G	rs11899661	23648065	4.36E-05	Allelic model	1.7	[1.33-2.17]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11899661-T	Research Support, Non-U.S. Gov't
2	192491453	rs6434494	A	G	rs6434494	23648065	4.51E-05	Allelic model	1.69	[1.32-2.16]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6434494-A	Research Support, Non-U.S. Gov't
2	192506225	rs6434497	G	T	rs6434497	23648065	9.31E-05	Recessive model	1.58	[1.24-2.02]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6434497-G	Research Support, Non-U.S. Gov't
2	192510265	rs5008133	T	C	rs5008133	23648065	3.28E-05	Recessive model	1.6	[1.25-2.05]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs5008133-A	Research Support, Non-U.S. Gov't
2	196365890	rs4591358	T	C	rs4591358	23648065	7.00E-06	Allelic model	1.58	[1.30-1.92]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4591358-C	Research Support, Non-U.S. Gov't
2	200638509	rs12615435	T	G	rs12615435	23648065	4.00E-06	Allelic model	2.21	[1.56-3.15]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12615435-T	Research Support, Non-U.S. Gov't
2	207418899	rs3770977	C	T	rs3770977	23648065	1.28E-05	Allelic model	2.97	[1.75-5.04]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs3770977-C	Research Support, Non-U.S. Gov't
2	214940734	rs6715771	T	C	rs6715771	23648065	2.02E-05	Dominant model	3.49	[1.94-6.26]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6715771-C	Research Support, Non-U.S. Gov't
2	215179277	rs6731110	C	A	rs6731110	23648065	9.24E-05	Dominant model	2.51	[1.44-4.38]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6731110-C	Research Support, Non-U.S. Gov't
2	217827849	rs2372928	A	G	rs2372928	23648065	5.70E-05	Recessive model	1.46	[1.16-1.84]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2372928-A	Research Support, Non-U.S. Gov't
2	217971141	rs2372972	T	C	rs2372972	23648065	8.94E-05	Allelic model	2.43	[1.55-3.83]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2372972-C	Research Support, Non-U.S. Gov't
2	217974444	rs13015994	A	C	rs13015994	23648065	2.08E-05	Allelic model	2.59	[1.68-4.00]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs13015994-G	Research Support, Non-U.S. Gov't
2	217980433	rs12466929	G	A	rs12466929	23648065	1.97E-05	Allelic model	2.68	[1.69-4.24]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12466929-C	Research Support, Non-U.S. Gov't
2	218512598	rs6733585	A	G	rs6733585	23648065	5.48E-05	Dominant model	8.66	[2.73-27.43]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6733585-A	Research Support, Non-U.S. Gov't
2	218754326	rs10174633	T	C	rs10174633	23648065	1.57E-05	Dominant model	1.39	[1.18-1.65]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10174633-A	Research Support, Non-U.S. Gov't
2	220926429	rs4674493	C	T	rs4674493	23648065	9.28E-05	Dominant model	2.09	[1.43-3.06]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4674493-G	Research Support, Non-U.S. Gov't
2	221000018	rs12614221	G	T	rs12614221	23648065	3.51E-05	Recessive model	2.02	[1.43-2.84]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12614221-A	Research Support, Non-U.S. Gov't
2	221762952	rs830747	G	A	rs830747	23648065	1.59E-05	Allelic model	3.83	[2.06-7.11]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs830747-G	Research Support, Non-U.S. Gov't
2	221927852	rs9808155	G	T	rs9808155	23648065	3.45E-05	Recessive model	1.5	[1.19-1.89]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9808155-A	Research Support, Non-U.S. Gov't
2	222330970	rs1430216	T	C	rs1430216	23648065	6.26E-05	Allelic model	2.59	[1.56-4.30]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1430216-T	Research Support, Non-U.S. Gov't
2	224943685	rs6740660	G	A	rs6740660	23648065	4.00E-06	Allelic model	3.39	[1.87-6.13]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6740660-G	Research Support, Non-U.S. Gov't
2	232077075	rs5018532	A	G	rs5018532	23648065	1.72E-05	Recessive model	1.46	[1.07-1.97]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs5018532-G	Research Support, Non-U.S. Gov't
2	232077075	rs5018532	A	G	rs5018532	23648065	6.74E-05	Recessive model	1.13	[0.92-1.39]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs5018532-G	Research Support, Non-U.S. Gov't
2	232077670	rs16827863	T	C	rs16827863	23648065	1.72E-05	Recessive model	1.46	[1.07-1.97]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs16827863-C	Research Support, Non-U.S. Gov't
2	232077670	rs16827863	T	C	rs16827863	23648065	6.89E-05	Recessive model	1.13	[0.92-1.39]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs16827863-C	Research Support, Non-U.S. Gov't
2	234669144	rs4148323	G	A	rs4148323	23648065	9.68E-05	Recessive model	1.64	[1.09-2.46]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4148323-A	Research Support, Non-U.S. Gov't
2	234888161	rs10207672	T	C	rs10207672	23648065	7.09E-05	Allelic model	2.33	[1.53-3.53]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10207672-C	Research Support, Non-U.S. Gov't
2	236589977	rs6750322	A	G	rs6750322	23648065	3.51E-05	Recessive model	1.43	[1.09-1.87]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6750322-C	Research Support, Non-U.S. Gov't
2	236813557	rs6747286	T	C	rs6747286	23648065	9.91E-05	Recessive model	1.34	[1.05-1.69]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6747286-C	Research Support, Non-U.S. Gov't
2	236832573	rs7571708	A	G	rs7571708	23648065	2.45E-05	Recessive model	1.41	[1.11-1.79]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7571708-T	Research Support, Non-U.S. Gov't
2	236834160	rs1962299	A	G	rs1962299	23648065	2.45E-05	Recessive model	1.4	[1.10-1.78]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1962299-T	Research Support, Non-U.S. Gov't
2	238806370	rs4663269	T	C	rs4663269	23648065	7.48E-05	Dominant model	1.34	[1.05-1.71]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4663269-T	Research Support, Non-U.S. Gov't
2	240399614	rs6726998	A	G	rs6726998	23648065	3.31E-05	Allelic model	2.21	[1.54-3.15]	150 Japanese ancestry cases; 166 Japanese ancestry controls	Japanese(316)	ALL(316)	ASN(316)	ALL(316)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6726998-C	Research Support, Non-U.S. Gov't
2	240871893	rs4853981	T	C	rs4853981	23648065	7.54E-05	Dominant model	1.56	[1.19-2.04]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4853981-G	Research Support, Non-U.S. Gov't
2	241819526	rs4675792	C	T	rs4675792	23648065	3.45E-05	Allelic model	1.68	[1.31-2.14]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4675792-C	Research Support, Non-U.S. Gov't
3	3101065	rs163579	C	T	rs163579	23648065	3.07E-05	Dominant model	4.48	[2.10-9.56]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs163579-G	Research Support, Non-U.S. Gov't
3	3193676	rs1669342	A	G	rs1669342	23648065	8.14E-05	Recessive model	1.6	[1.21-2.12]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1669342-G	Research Support, Non-U.S. Gov't
3	5938105	rs12233495	C	T	rs12233495	23648065	1.19E-05	Dominant model	3.32	[1.78-6.21]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12233495-G	Research Support, Non-U.S. Gov't
3	6002693	rs6767324	G	A	rs6767324	23648065	1.89E-05	Dominant model	3.01	[1.62-5.58]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6767324-G	Research Support, Non-U.S. Gov't
3	6002768	rs6807385	T	C	rs6807385	23648065	1.89E-05	Dominant model	3.01	[1.62-5.58]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6807385-A	Research Support, Non-U.S. Gov't
3	6005401	rs6768819	T	C	rs6768819	23648065	2.31E-05	Dominant model	2.87	[1.55-5.30]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6768819-A	Research Support, Non-U.S. Gov't
3	7010081	rs480409	C	T	rs480409	23648065	9.00E-06	Recessive model	1.84	[1.31-2.60]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs480409-G	Research Support, Non-U.S. Gov't
3	7012842	rs6796324	G	A	rs6796324	23648065	2.86E-05	Dominant model	2.54	[1.62-3.98]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6796324-A	Research Support, Non-U.S. Gov't
3	7083814	rs1353832	C	T	rs1353832	23648065	3.99E-05	Allelic model	2.22	[1.53-3.21]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1353832-C	Research Support, Non-U.S. Gov't
3	7152640	rs9876724	G	A	rs9876724	23648065	4.97E-05	Dominant model	1.35	[1.14-1.60]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9876724-G	Research Support, Non-U.S. Gov't
3	7170011	rs6766686	A	G	rs6766686	23648065	6.90E-05	Recessive model	1.36	[1.02-1.81]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6766686-T	Research Support, Non-U.S. Gov't
3	7505487	rs1868616	A	G	rs1868616	23648065	7.77E-05	Dominant model	2.09	[1.35-3.23]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1868616-A	Research Support, Non-U.S. Gov't
3	7898720	rs13323237	C	T	rs13323237	23648065	9.94E-05	Dominant model	1.61	[1.22-2.13]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs13323237-G	Research Support, Non-U.S. Gov't
3	10258493	rs2302862	T	C	rs2302862	23648065	3.42E-05	Dominant model	4.91	[2.23-10.80]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2302862-A	Research Support, Non-U.S. Gov't
3	13866499	rs4685039	G	A	rs4685039	23648065	6.97E-05	Dominant model	1.76	[1.22-2.54]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4685039-T	Research Support, Non-U.S. Gov't
3	14345707	rs9883639	C	T	rs9883639	23648065	6.96E-05	Allelic model	1.73	[1.32-2.25]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9883639-C	Research Support, Non-U.S. Gov't
3	16169491	rs7624406	A	G	rs7624406	23648065	2.74E-05	Dominant model	1.95	[1.39-2.72]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7624406-G	Research Support, Non-U.S. Gov't
3	16196224	rs6775152	G	A	rs6775152	23648065	2.21E-05	Allelic model	1.66	[1.31-2.09]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6775152-T	Research Support, Non-U.S. Gov't
3	16196224	rs6775152	G	A	rs6775152	23648065	4.36E-05	Allelic model	1.44	[1.21-1.72]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6775152-T	Research Support, Non-U.S. Gov't
3	21361784	rs13059346	T	C	rs13059346	23648065	2.59E-05	Dominant model	4.22	[2.06-8.63]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs13059346-G	Research Support, Non-U.S. Gov't
3	24173744	rs1705734	A	G	rs1705734	23648065	8.66E-05	Allelic model	2.12	[1.47-3.06]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1705734-T	Research Support, Non-U.S. Gov't
3	24267140	rs826223	A	G	rs826223	23648065	4.76E-05	Dominant model	1.31	[1.10-1.57]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs826223-T	Research Support, Non-U.S. Gov't
3	25383258	rs4681047	A	G	rs4681047	23648065	5.06E-05	Allelic model	2.29	[1.54-3.38]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4681047-G	Research Support, Non-U.S. Gov't
3	32125010	rs7643045	G	A	rs7643045	23648065	1.98E-05	Recessive model	1.32	[1.10-1.57]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7643045-G	Research Support, Non-U.S. Gov't
3	40174858	rs9878321	A	G	rs9878321	23648065	7.15E-05	Allelic model	1.84	[1.36-2.48]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9878321-A	Research Support, Non-U.S. Gov't
3	55231799	rs1381389	G	A	rs1381389	23648065	8.45E-05	Recessive model	3.5	[1.87-6.54]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1381389-T	Research Support, Non-U.S. Gov't
3	55236699	rs12491607	C	A,G,T	rs12491607	23648065	5.10E-05	Allelic model	3.52	[1.91-6.49]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12491607-A	Research Support, Non-U.S. Gov't
3	55237738	rs10510777	C	T	rs10510777	23648065	3.06E-05	Recessive model	3.69	[1.98-6.88]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10510777-A	Research Support, Non-U.S. Gov't
3	55241137	rs6802697	T	C	rs6802697	23648065	5.14E-05	Allelic model	3.68	[1.97-6.89]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6802697-A	Research Support, Non-U.S. Gov't
3	55256432	rs374563	C	A	rs374563	23648065	4.97E-05	Allelic model	3.63	[1.92-6.84]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs374563-A	Research Support, Non-U.S. Gov't
3	55263442	rs535157	A	C	rs535157	23648065	2.73E-05	Allelic model	3.76	[2.02-7.00]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs535157-T	Research Support, Non-U.S. Gov't
3	55265674	rs393836	A	C	rs393836	23648065	8.87E-05	Allelic model	3.52	[1.88-6.61]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs393836-C	Research Support, Non-U.S. Gov't
3	58025903	rs1718481	C	T	rs1718481	23648065	1.67E-05	Recessive model	1.67	[1.29-2.14]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1718481-T	Research Support, Non-U.S. Gov't
3	58025903	rs1718481	C	T	rs1718481	23648065	7.53E-05	Allelic model	2.02	[1.43-2.84]	150 Japanese ancestry cases; 166 Japanese ancestry controls	Japanese(316)	ALL(316)	ASN(316)	ALL(316)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1718481-T	Research Support, Non-U.S. Gov't
3	58027197	rs1623879	A	G	rs1623879	23648065	4.00E-06	Recessive model	1.67	[1.30-2.15]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1623879-G	Research Support, Non-U.S. Gov't
3	58036792	rs839230	C	T	rs839230	23648065	2.60E-05	Recessive model	1.66	[1.29-2.13]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs839230-T	Research Support, Non-U.S. Gov't
3	58036792	rs839230	C	T	rs839230	23648065	5.97E-05	Allelic model	2	[1.42-2.81]	150 Japanese ancestry cases; 166 Japanese ancestry controls	Japanese(316)	ALL(316)	ASN(316)	ALL(316)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs839230-T	Research Support, Non-U.S. Gov't
3	58045538	rs1249968	C	T	rs1249968	23648065	2.37E-05	Recessive model	1.55	[1.21-1.98]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1249968-T	Research Support, Non-U.S. Gov't
3	58045538	rs1249968	C	T	rs1249968	23648065	6.52E-05	Allelic model	2.02	[1.43-2.84]	150 Japanese ancestry cases; 166 Japanese ancestry controls	Japanese(316)	ALL(316)	ASN(316)	ALL(316)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1249968-T	Research Support, Non-U.S. Gov't
3	64009102	rs35836	G	T	rs35836	23648065	9.56E-05	Dominant model	3.71	[1.86-7.42]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs35836-A	Research Support, Non-U.S. Gov't
3	66525963	rs3845905	T	C	rs3845905	23648065	4.00E-06	Allelic model	1.89	[1.43-2.50]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs3845905-G	Research Support, Non-U.S. Gov't
3	66525963	rs3845905	T	C	rs3845905	23648065	6.00E-06	Allelic model	2.43	[1.65-3.60]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs3845905-G	Research Support, Non-U.S. Gov't
3	69034385	rs2033773	G	T	rs2033773	23648065	7.42E-05	Dominant model	2.01	[1.39-2.91]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2033773-C	Research Support, Non-U.S. Gov't
3	69694906	rs17006293	C	T	rs17006293	23648065	9.38E-05	Allelic model	1.76	[1.33-2.34]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs17006293-C	Research Support, Non-U.S. Gov't
3	71737107	rs3796226	A	G	rs3796226	23648065	4.64E-05	Allelic model	1.81	[1.36-2.41]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs3796226-C	Research Support, Non-U.S. Gov't
3	76806018	rs7609557	A	G	rs7609557	23648065	8.15E-05	Recessive model	2	[1.28-3.12]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7609557-C	Research Support, Non-U.S. Gov't
3	76850916	rs1167035	C	T	rs1167035	23648065	4.48E-05	Recessive model	1.95	[1.25-3.04]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1167035-T	Research Support, Non-U.S. Gov't
3	77643174	rs775723	G	T	rs775723	23648065	6.94E-05	Allelic model	2.42	[1.57-3.73]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs775723-T	Research Support, Non-U.S. Gov't
3	77675638	rs876675	C	T	rs876675	23648065	3.96E-05	Allelic model	2.53	[1.64-3.91]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs876675-A	Research Support, Non-U.S. Gov't
3	77675638	rs876675	C	T	rs876675	23648065	4.86E-05	Allelic model	2.09	[1.47-2.97]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs876675-A	Research Support, Non-U.S. Gov't
3	87274437	rs904115	T	G	rs904115	23648065	5.93E-05	Allelic model	2.53	[1.62-3.96]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs904115-A	Research Support, Non-U.S. Gov't
3	87373894	rs4859055	C	T	rs4859055	23648065	4.91E-05	Allelic model	4.66	[2.24-9.72]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4859055-G	Research Support, Non-U.S. Gov't
3	87373894	rs4859055	C	T	rs4859055	23648065	7.24E-05	Allelic model	3.39	[1.85-6.22]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4859055-G	Research Support, Non-U.S. Gov't
3	95617191	rs980856	A	G	rs980856	23648065	3.85E-05	Allelic model	1.84	[1.36-2.49]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs980856-C	Research Support, Non-U.S. Gov't
3	106089227	rs9831569	C	T	rs9831569	23648065	5.35E-05	Recessive model	1.63	[1.28-2.09]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9831569-A	Research Support, Non-U.S. Gov't
3	107003691	rs16853338	G	A	rs16853338	23648065	3.90E-05	Dominant model	1.35	[1.14-1.60]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs16853338-T	Research Support, Non-U.S. Gov't
3	107019713	rs809421	A	G	rs809421	23648065	8.71E-05	Dominant model	1.31	[1.10-1.56]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs809421-C	Research Support, Non-U.S. Gov't
3	122128394	rs1127343	G	A	rs1127343	23648065	5.48E-05	Allelic model	2.17	[1.47-3.23]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1127343-A	Research Support, Non-U.S. Gov't
3	124499685	rs3772827	C	T	rs3772827	23648065	4.05E-05	Allelic model	2.82	[1.75-4.54]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs3772827-A	Research Support, Non-U.S. Gov't
3	124515395	rs2291086	G	A	rs2291086	23648065	6.71E-05	Allelic model	2.65	[1.66-4.23]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2291086-T	Research Support, Non-U.S. Gov't
3	124515636	rs2291089	C	T	rs2291089	23648065	3.18E-05	Allelic model	2.78	[1.73-4.45]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2291089-A	Research Support, Non-U.S. Gov't
3	124545750	rs6771896	G	A	rs6771896	23648065	4.21E-05	Allelic model	2.53	[1.59-4.03]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6771896-C	Research Support, Non-U.S. Gov't
3	124546047	rs4677946	A	G	rs4677946	23648065	6.17E-05	Allelic model	2.59	[1.60-4.21]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4677946-A	Research Support, Non-U.S. Gov't
3	124550364	rs3772840	C	T	rs3772840	23648065	8.52E-05	Allelic model	2.32	[1.51-3.56]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs3772840-A	Research Support, Non-U.S. Gov't
3	124610238	rs7373878	G	T	rs7373878	23648065	1.50E-05	Allelic model	2.7	[1.68-4.36]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7373878-A	Research Support, Non-U.S. Gov't
3	145921954	rs9839874	T	C	rs9839874	23648065	9.58E-05	Allelic model	1.58	[1.26-1.99]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9839874-T	Research Support, Non-U.S. Gov't
3	146394094	rs10935638	C	T	rs10935638	23648065	1.75E-05	Recessive model	2.12	[1.36-3.30]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10935638-A	Research Support, Non-U.S. Gov't
3	156821808	rs6441111	C	T	rs6441111	23648065	5.58E-05	Dominant model	1.21	[1.01-1.45]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6441111-T	Research Support, Non-U.S. Gov't
3	157054271	rs988587	T	G	rs988587	23648065	1.79E-05	Allelic model	1.76	[1.35-2.29]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs988587-C	Research Support, Non-U.S. Gov't
3	157054271	rs988587	T	G	rs988587	23648065	6.74E-05	Allelic model	2.11	[1.46-3.05]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs988587-C	Research Support, Non-U.S. Gov't
3	157088982	rs9883103	C	T	rs9883103	23648065	8.25E-05	Allelic model	1.58	NA	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9883103-A	Research Support, Non-U.S. Gov't
3	157094479	rs4680360	T	C	rs4680360	23648065	4.26E-05	Allelic model	1.71	[1.32-2.22]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4680360-C	Research Support, Non-U.S. Gov't
3	157113276	rs12486427	A	C	rs12486427	23648065	2.64E-05	Allelic model	1.73	[1.33-2.24]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12486427-G	Research Support, Non-U.S. Gov't
3	157125584	rs6803628	G	A	rs6803628	23648065	2.85E-05	Allelic model	1.69	[1.32-2.18]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6803628-A	Research Support, Non-U.S. Gov't
3	157166123	rs4680367	G	A	rs4680367	23648065	1.68E-05	Allelic model	1.77	[1.36-2.31]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4680367-T	Research Support, Non-U.S. Gov't
3	159714802	rs2243143	G	A	rs2243143	23648065	6.19E-05	Recessive model	1.22	[0.96-1.55]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2243143-C	Research Support, Non-U.S. Gov't
3	159718268	rs6441284	A	G	rs6441284	23648065	6.19E-05	Recessive model	1.19	[0.94-1.51]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6441284-A	Research Support, Non-U.S. Gov't
3	161460016	rs16833312	C	T	rs16833312	23648065	2.00E-05	Dominant model	5.18	[2.23-12.02]	150 Japanese ancestry cases; 166 Japanese ancestry controls	Japanese(316)	ALL(316)	ASN(316)	ALL(316)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs16833312-G	Research Support, Non-U.S. Gov't
3	161490079	rs1515730	G	A	rs1515730	23648065	3.57E-05	Allelic model	3.69	[1.89-7.21]	150 Japanese ancestry cases; 166 Japanese ancestry controls	Japanese(316)	ALL(316)	ASN(316)	ALL(316)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1515730-G	Research Support, Non-U.S. Gov't
3	168644514	rs6768780	C	A	rs6768780	23648065	5.68E-05	Dominant model	3.04	[1.77-5.22]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6768780-T	Research Support, Non-U.S. Gov't
3	174038312	rs13098004	C	A	rs13098004	23648065	2.90E-05	Allelic model	1.99	[1.44-2.75]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs13098004-C	Research Support, Non-U.S. Gov't
3	178357197	rs9847335	A	G	rs9847335	23648065	1.86E-05	Dominant model	3.11	[1.73-5.60]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9847335-T	Research Support, Non-U.S. Gov't
3	178365840	rs7615444	A	C	rs7615444	23648065	5.83E-05	Allelic model	2.82	[1.71-4.65]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7615444-T	Research Support, Non-U.S. Gov't
3	178449906	rs6443571	G	A	rs6443571	23648065	1.89E-05	Allelic model	2.9	[1.78-4.71]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6443571-G	Research Support, Non-U.S. Gov't
3	181340141	rs13086529	A	G	rs13086529	23648065	6.31E-05	Recessive model	1.34	[1.00-1.79]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs13086529-C	Research Support, Non-U.S. Gov't
3	187710426	rs9860469	A	G	rs9860469	23648065	5.70E-05	Recessive model	1.51	[1.07-2.13]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9860469-C	Research Support, Non-U.S. Gov't
3	187716886	rs1553091	A	G	rs1553091	23648065	7.00E-06	Recessive model	1.48	[1.05-2.08]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1553091-G	Research Support, Non-U.S. Gov't
3	187719473	rs9843063	G	A	rs9843063	23648065	5.70E-05	Recessive model	1.49	[1.05-2.11]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9843063-A	Research Support, Non-U.S. Gov't
3	187727515	rs11924318	G	A	rs11924318	23648065	7.12E-05	Recessive model	1.46	[1.04-2.07]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11924318-T	Research Support, Non-U.S. Gov't
3	192562429	rs9870609	A	G	rs9870609	23648065	3.83E-05	Recessive model	1.33	[1.11-1.59]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9870609-G	Research Support, Non-U.S. Gov't
3	194000979	rs9862745	C	T	rs9862745	23648065	5.74E-05	Allelic model	1.6	[1.27-2.01]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9862745-T	Research Support, Non-U.S. Gov't
3	196369163	rs76036994	GA	G	rs843522	23648065	5.04E-05	Dominant model	1.58	[1.22-2.03]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs843522-G	Research Support, Non-U.S. Gov't
3	196369163	rs843522	G	A	rs843522	23648065	5.04E-05	Dominant model	1.58	[1.22-2.03]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs843522-G	Research Support, Non-U.S. Gov't
4	4333387	rs6855893	T	C	rs6855893	23648065	6.13E-05	Recessive model	1.58	[1.19-2.10]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6855893-G	Research Support, Non-U.S. Gov't
4	6065298	rs17766228	T	C	rs17766228	23648065	8.44E-05	Recessive model	1.63	[1.16-2.30]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs17766228-A	Research Support, Non-U.S. Gov't
4	6367467	rs6831971	T	C	rs6831971	23648065	7.66E-05	Recessive model	1.28	[1.07-1.53]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6831971-G	Research Support, Non-U.S. Gov't
4	7262170	rs904989	C	T	rs904989	23648065	8.39E-05	Recessive model	1.27	[1.07-1.52]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs904989-G	Research Support, Non-U.S. Gov't
4	10883658	rs1483660	T	C	rs1483660	23648065	1.31E-05	Recessive model	1.35	[1.13-1.61]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1483660-G	Research Support, Non-U.S. Gov't
4	31718284	rs10489008	A	C	rs10489008	23648065	4.30E-05	Recessive model	2.14	[1.33-3.45]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10489008-A	Research Support, Non-U.S. Gov't
4	36021619	rs872322	G	A	rs872322	23648065	1.40E-05	Allelic model	2.63	[1.63-4.26]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs872322-A	Research Support, Non-U.S. Gov't
4	36021619	rs872322	G	A	rs872322	23648065	2.12E-05	Allelic model	1.96	[1.41-2.73]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs872322-A	Research Support, Non-U.S. Gov't
4	36026747	rs1567482	T	C	rs1567482	23648065	6.00E-06	Allelic model	2.85	[1.72-4.72]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1567482-G	Research Support, Non-U.S. Gov't
4	46898265	rs7683552	T	C	rs7683552	23648065	5.82E-05	Allelic model	2.01	[1.43-2.82]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7683552-C	Research Support, Non-U.S. Gov't
4	46941018	rs1028005	A	G	rs1028005	23648065	8.56E-05	Allelic model	1.98	[1.41-2.78]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1028005-G	Research Support, Non-U.S. Gov't
4	52798624	rs1996617	T	C	rs1996617	23648065	8.87E-05	Allelic model	3.52	[1.88-6.61]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1996617-A	Research Support, Non-U.S. Gov't
4	52810307	rs6829655	T	C	rs6829655	23648065	8.87E-05	Allelic model	3.52	[1.88-6.61]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6829655-T	Research Support, Non-U.S. Gov't
4	52830444	rs11735705	T	G	rs11735705	23648065	8.87E-05	Allelic model	3.52	[1.88-6.61]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11735705-T	Research Support, Non-U.S. Gov't
4	52860156	rs1519588	C	T	rs1519588	23648065	4.82E-05	Allelic model	3.66	[1.95-6.86]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1519588-G	Research Support, Non-U.S. Gov't
4	52867437	rs7695726	A	C	rs7695726	23648065	8.87E-05	Allelic model	3.52	[1.88-6.61]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7695726-A	Research Support, Non-U.S. Gov't
4	52871894	rs4610396	G	T	rs4610396	23648065	8.87E-05	Allelic model	3.52	[1.88-6.61]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4610396-C	Research Support, Non-U.S. Gov't
4	52888026	rs170424	A	C	rs170424	23648065	8.87E-05	Allelic model	3.52	[1.88-6.61]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs170424-C	Research Support, Non-U.S. Gov't
4	55913934	rs7441352	A	G	rs7441352	23648065	5.78E-05	Allelic model	1.67	[1.30-2.13]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7441352-A	Research Support, Non-U.S. Gov't
4	57300557	rs1520026	C	T	rs1520026	23648065	5.21E-05	Allelic model	1.43	[1.21-1.71]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1520026-T	Research Support, Non-U.S. Gov't
4	62240526	rs6858223	A	G	rs6858223	23648065	1.39E-05	Allelic model	1.65	[1.32-2.06]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6858223-G	Research Support, Non-U.S. Gov't
4	63407579	rs2168267	C	T	rs2168267	23648065	5.48E-05	Allelic model	1.8	[1.35-2.40]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2168267-A	Research Support, Non-U.S. Gov't
4	63424089	rs11944965	C	T	rs11944965	23648065	2.00E-06	Dominant model	1.99	[1.48-2.68]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11944965-T	Research Support, Non-U.S. Gov't
4	82133264	rs989445	C	A	rs989445	23648065	3.88E-05	Dominant model	3.84	[1.93-7.63]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs989445-C	Research Support, Non-U.S. Gov't
4	82616045	rs6535273	T	C	rs6535273	23648065	2.80E-05	Recessive model	1.29	[1.08-1.54]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6535273-A	Research Support, Non-U.S. Gov't
4	85205214	rs1495151	G	A	rs1495151	23648065	9.46E-05	Allelic model	1.69	[1.30-2.19]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1495151-A	Research Support, Non-U.S. Gov't
4	87473776	rs4478147	G	A	rs4478147	23648065	4.00E-05	Dominant model	1.51	[1.18-1.93]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4478147-G	Research Support, Non-U.S. Gov't
4	91253355	rs10015182	C	T	rs10015182	23648065	1.75E-05	Recessive model	1.3	[1.09-1.55]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10015182-T	Research Support, Non-U.S. Gov't
4	99459528	rs2037832	C	T	rs2037832	23648065	9.50E-05	Recessive model	1.68	[1.16-2.42]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2037832-G	Research Support, Non-U.S. Gov't
4	104545224	rs3796974	T	C	rs3796974	23648065	1.73E-05	Allelic model	1.76	[1.36-2.28]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs3796974-A	Research Support, Non-U.S. Gov't
4	104552687	rs12641703	G	A	rs12641703	23648065	3.02E-05	Allelic model	1.74	[1.35-2.25]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12641703-C	Research Support, Non-U.S. Gov't
4	105921314	rs12500787	G	T	rs12500787	23648065	3.28E-05	Allelic model	3.64	[1.89-7.00]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12500787-T	Research Support, Non-U.S. Gov't
4	112557798	rs983966	G	A	rs983966	23648065	5.34E-05	Dominant model	1.92	[1.30-2.83]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs983966-T	Research Support, Non-U.S. Gov't
4	112588951	rs1450781	T	C	rs1450781	23648065	1.93E-05	Dominant model	2	[1.35-2.95]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1450781-G	Research Support, Non-U.S. Gov't
4	113328078	rs6838440	C	T	rs6838440	21799462	3.00E-06	NA	2.1	[1.49-2.96]	67 Japanese ancestry cases; 203 Japanese ancestry controls	Japanese(270)	ALL(270)	ASN(270)	ALL(270)	Epirubicin-induced leukopenia	HPOID:0001882	Leukopenia	DOID:615	leukopenia	D007970	Leukopenia	EFOID:0004233	leukopenia	Leukopenia	rs6838440-C	Research Support, Non-U.S. Gov't	C	ALPK1
4	120756608	rs17363983	T	G	rs17363983	23648065	2.56E-05	Recessive model	1.5	[1.19-1.91]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs17363983-C	Research Support, Non-U.S. Gov't
4	120760872	rs7688177	T	C	rs7688177	23648065	2.72E-05	Allelic model	1.86	[1.40-2.48]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7688177-C	Research Support, Non-U.S. Gov't
4	125298963	rs1159819	G	A	rs1159819	23648065	9.20E-05	Allelic model	1.52	[1.23-1.89]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1159819-T	Research Support, Non-U.S. Gov't
4	125320611	rs17008117	C	T	rs17008117	23648065	9.20E-05	Allelic model	1.52	[1.23-1.89]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs17008117-G	Research Support, Non-U.S. Gov't
4	130185974	rs9994767	C	T	rs9994767	23648065	4.62E-05	Recessive model	1.38	[1.09-1.75]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9994767-C	Research Support, Non-U.S. Gov't
4	130375150	rs1433384	T	C	rs1433384	23648065	1.33E-05	Allelic model	1.52	[1.26-1.83]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1433384-C	Research Support, Non-U.S. Gov't
4	130731072	rs2391504	A	G	rs2391504	23648065	5.68E-05	Dominant model	1.91	[1.40-2.61]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2391504-T	Research Support, Non-U.S. Gov't
4	130767230	rs10028795	G	A	rs10028795	23648065	6.09E-05	Recessive model	1.31	[1.10-1.56]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10028795-G	Research Support, Non-U.S. Gov't
4	130767899	rs17050689	T	C	rs17050689	23648065	6.09E-05	Recessive model	1.31	[1.10-1.56]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs17050689-T	Research Support, Non-U.S. Gov't
4	131238094	rs1022079	C	A	rs1022079	23648065	6.10E-05	Allelic model	1.88	[1.39-2.55]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1022079-A	Research Support, Non-U.S. Gov't
4	133858930	rs11099230	A	G	rs11099230	23648065	2.05E-05	Dominant model	1.79	[1.30-2.47]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11099230-G	Research Support, Non-U.S. Gov't
4	133862954	rs12641896	A	G	rs12641896	23648065	3.23E-05	Dominant model	1.67	[1.25-2.25]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12641896-C	Research Support, Non-U.S. Gov't
4	137953807	rs515800	T	C	rs515800	23648065	7.32E-05	Dominant model	1.51	[1.16-1.98]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs515800-T	Research Support, Non-U.S. Gov't
4	138161364	rs4561979	T	C	rs4561979	23648065	5.08E-05	Dominant model	1.65	[1.27-2.14]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4561979-T	Research Support, Non-U.S. Gov't
4	138367052	rs7698992	T	C	rs7698992	23648065	3.39E-05	Dominant model	1.99	[1.36-2.90]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7698992-T	Research Support, Non-U.S. Gov't
4	138369786	rs10519425	G	A	rs10519425	23648065	3.39E-05	Dominant model	1.99	[1.36-2.90]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10519425-G	Research Support, Non-U.S. Gov't
4	139336708	rs2976499	C	T	rs2976499	23648065	8.38E-05	Dominant model	1.59	[1.12-2.25]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2976499-G	Research Support, Non-U.S. Gov't
4	139336851	rs11732157	C	T	rs11732157	23648065	8.88E-05	Dominant model	1.79	[1.22-2.63]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11732157-G	Research Support, Non-U.S. Gov't
4	139494811	rs1376086	A	G	rs1376086	23648065	7.91E-05	Dominant model	1.52	[1.19-1.93]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1376086-C	Research Support, Non-U.S. Gov't
4	140497312	rs11726931	T	C	rs11726931	23648065	9.06E-05	Allelic model	2.54	[1.56-4.12]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11726931-A	Research Support, Non-U.S. Gov't
4	142792211	rs17015119	G	A	rs17015119	23648065	8.53E-05	Dominant model	1.33	[1.06-1.67]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs17015119-T	Research Support, Non-U.S. Gov't
4	146867376	rs6537382	C	A	rs6537382	23648065	2.37E-05	Allelic model	2.28	[1.56-3.32]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6537382-C	Research Support, Non-U.S. Gov't
4	153879878	rs11737767	C	T	rs11737767	23648065	3.33E-05	Recessive model	1.61	[1.28-2.03]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11737767-T	Research Support, Non-U.S. Gov't
4	154369706	rs13105829	C	T	rs13105829	23648065	3.62E-05	Allelic model	1.48	[1.23-1.78]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs13105829-T	Research Support, Non-U.S. Gov't
4	154369706	rs13105829	C	T	rs13105829	23648065	8.34E-05	Allelic model	1.46	[1.21-1.76]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs13105829-T	Research Support, Non-U.S. Gov't
4	154371229	rs11941933	C	T	rs11941933	23648065	3.03E-05	Allelic model	1.48	[1.23-1.79]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11941933-A	Research Support, Non-U.S. Gov't
4	154371229	rs11941933	C	T	rs11941933	23648065	6.86E-05	Allelic model	1.47	[1.22-1.77]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11941933-A	Research Support, Non-U.S. Gov't
4	154373196	rs11728644	G	A	rs11728644	23648065	2.06E-05	Allelic model	1.5	[1.25-1.80]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11728644-A	Research Support, Non-U.S. Gov't
4	154373196	rs11728644	G	A	rs11728644	23648065	2.55E-05	Allelic model	1.5	[1.24-1.80]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11728644-A	Research Support, Non-U.S. Gov't
4	154374984	rs6817170	T	C	rs6817170	23648065	9.00E-06	Allelic model	1.52	[1.26-1.82]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6817170-G	Research Support, Non-U.S. Gov't
4	154376222	rs11732163	G	A	rs11732163	23648065	1.35E-05	Allelic model	1.51	[1.26-1.81]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11732163-T	Research Support, Non-U.S. Gov't
4	154376222	rs11732163	G	A	rs11732163	23648065	2.66E-05	Allelic model	1.48	[1.24-1.78]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11732163-T	Research Support, Non-U.S. Gov't
4	154378572	rs1560940	A	G	rs1560940	23648065	2.67E-05	Allelic model	1.49	[1.24-1.79]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1560940-C	Research Support, Non-U.S. Gov't
4	154389653	rs1836401	A	G	rs1836401	23648065	2.36E-05	Allelic model	1.49	[1.24-1.79]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1836401-C	Research Support, Non-U.S. Gov't
4	154389653	rs1836401	A	G	rs1836401	23648065	3.87E-05	Allelic model	1.47	[1.23-1.77]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1836401-C	Research Support, Non-U.S. Gov't
4	154408454	rs713248	A	G	rs713248	23648065	1.63E-05	Allelic model	1.5	[1.25-1.79]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs713248-C	Research Support, Non-U.S. Gov't
4	154408454	rs713248	A	G	rs713248	23648065	1.92E-05	Allelic model	1.49	[1.25-1.79]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs713248-C	Research Support, Non-U.S. Gov't
4	156311510	rs7663620	G	A	rs7663620	23648065	7.77E-05	Dominant model	1.81	[1.31-2.49]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7663620-A	Research Support, Non-U.S. Gov't
4	156322989	rs11100000	C	T	rs11100000	23648065	4.59E-05	Dominant model	1.85	[1.33-2.58]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11100000-A	Research Support, Non-U.S. Gov't
4	157683685	rs1425486	C	T	rs1425486	23648065	7.87E-05	Recessive model	3.77	[1.95-7.29]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1425486-C	Research Support, Non-U.S. Gov't
4	162953565	rs1471693	G	A	rs1471693	23648065	3.64E-05	Allelic model	1.85	[1.38-2.49]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1471693-G	Research Support, Non-U.S. Gov't
4	162985367	rs1492457	G	A	rs1492457	23648065	3.68E-05	Dominant model	1.66	[1.30-2.11]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1492457-T	Research Support, Non-U.S. Gov't
4	162992246	rs2086754	A	C	rs2086754	23648065	5.58E-05	Dominant model	1.62	[1.28-2.05]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2086754-C	Research Support, Non-U.S. Gov't
4	163243053	rs4440177	G	A	rs4440177	23648065	4.16E-05	Allelic model	1.75	[1.34-2.28]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4440177-T	Research Support, Non-U.S. Gov't
4	170975204	rs12650424	T	C	rs12650424	23648065	2.35E-05	Recessive model	1.23	[1.03-1.48]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12650424-C	Research Support, Non-U.S. Gov't
4	174751009	rs6833126	T	C	rs6833126	23648065	9.06E-05	Dominant model	2	[1.36-2.96]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6833126-A	Research Support, Non-U.S. Gov't
4	175674144	rs13113891	A	G	rs13113891	23648065	9.39E-05	Dominant model	1.88	[1.30-2.71]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs13113891-A	Research Support, Non-U.S. Gov't
4	178201257	rs4690504	C	T	rs4690504	23648065	5.07E-05	Dominant model	1.81	[1.28-2.55]	150 Japanese ancestry cases; 166 Japanese ancestry controls	Japanese(316)	ALL(316)	ASN(316)	ALL(316)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4690504-G	Research Support, Non-U.S. Gov't
4	180537212	rs17067866	T	C	rs17067866	23648065	6.23E-05	Allelic model	2.48	[1.56-3.95]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs17067866-T	Research Support, Non-U.S. Gov't
4	181907769	rs10016729	A	G	rs10016729	23648065	1.40E-05	Recessive model	1.39	[1.14-1.70]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10016729-T	Research Support, Non-U.S. Gov't
4	185946538	rs6851788	T	C	rs6851788	23648065	7.39E-05	Dominant model	1.84	[1.15-2.94]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6851788-C	Research Support, Non-U.S. Gov't
4	186695208	rs4487396	C	T	rs4487396	23648065	2.76E-05	Recessive model	1.44	[1.00-2.07]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4487396-C	Research Support, Non-U.S. Gov't
4	187382294	rs12506228	C	A	rs12506228	23648065	2.67E-05	Allelic model	1.89	[1.41-2.53]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12506228-A	Research Support, Non-U.S. Gov't
4	187851352	rs7657521	C	T	rs7657521	23648065	1.49E-05	Recessive model	1.35	[1.09-1.67]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7657521-C	Research Support, Non-U.S. Gov't
4	188114879	rs7692743	G	A	rs7692743	23648065	2.95E-05	Allelic model	2.87	[1.76-4.69]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7692743-C	Research Support, Non-U.S. Gov't
5	1468287	rs4975648	C	A	rs4975648	23648065	9.76E-05	Recessive model	2.52	[1.57-4.03]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4975648-G	Research Support, Non-U.S. Gov't
5	1936443	rs2129470	C	A	rs2129470	23648065	4.56E-05	Recessive model	1.13	[0.83-1.53]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2129470-C	Research Support, Non-U.S. Gov't
5	3132559	rs469508	C	T	rs469508	23648065	4.22E-05	Allelic model	1.87	[1.39-2.52]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs469508-T	Research Support, Non-U.S. Gov't
5	3174785	rs12657403	G	A	rs12657403	23648065	9.91E-05	Allelic model	1.83	[1.35-2.48]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12657403-A	Research Support, Non-U.S. Gov't
5	5407814	rs2964475	T	G	rs2964475	23648065	4.00E-06	Allelic model	2.25	[1.59-3.17]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2964475-C	Research Support, Non-U.S. Gov't
5	5415012	rs2913356	T	C	rs2913356	23648065	4.94E-05	Allelic model	2.04	[1.44-2.87]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2913356-G	Research Support, Non-U.S. Gov't
5	13816740	rs16902777	G	A	rs16902777	23648065	8.38E-05	Allelic model	3.41	[1.85-6.29]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs16902777-G	Research Support, Non-U.S. Gov't
5	14989823	rs2402022	T	C	rs2402022	23648065	6.36E-05	Dominant model	1.69	[1.10-2.60]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2402022-T	Research Support, Non-U.S. Gov't
5	27343904	rs2329426	T	C	rs2329426	23648065	5.72E-05	Allelic model	1.62	[1.27-2.06]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2329426-T	Research Support, Non-U.S. Gov't
5	27987104	rs4537065	G	A	rs4537065	23648065	6.50E-05	Recessive model	2.01	[1.43-2.83]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4537065-A	Research Support, Non-U.S. Gov't
5	27992491	rs2876936	C	T	rs2876936	23648065	6.50E-05	Recessive model	2.01	[1.43-2.83]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2876936-A	Research Support, Non-U.S. Gov't
5	28006650	rs4398645	T	C	rs4398645	23648065	6.50E-05	Recessive model	2.01	[1.43-2.83]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4398645-G	Research Support, Non-U.S. Gov't
5	28017229	rs1494617	T	C	rs1494617	23648065	6.50E-05	Recessive model	2.01	[1.43-2.83]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1494617-C	Research Support, Non-U.S. Gov't
5	31838491	rs6874198	A	G	rs6874198	23648065	2.81E-05	Allelic model	1.59	[1.27-1.98]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6874198-A	Research Support, Non-U.S. Gov't
5	35799994	rs3822735	A	G	rs3822735	23648065	2.00E-06	Dominant model	2.06	[1.50-2.83]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs3822735-G	Research Support, Non-U.S. Gov't
5	38203031	rs6451374	G	T	rs6451374	23648065	4.22E-05	Allelic model	1.75	[1.34-2.28]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6451374-T	Research Support, Non-U.S. Gov't
5	50391229	rs17820197	C	T	rs17820197	23648065	7.17E-05	Recessive model	1.3	[1.04-1.62]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs17820197-A	Research Support, Non-U.S. Gov't
5	51124949	rs7713485	C	T	rs7713485	23648065	8.20E-05	Recessive model	1.43	[0.93-2.20]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7713485-A	Research Support, Non-U.S. Gov't
5	52003387	rs351929	A	C	rs351929	23648065	7.69E-05	Allelic model	1.59	[1.26-1.99]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs351929-C	Research Support, Non-U.S. Gov't
5	54184663	rs2075401	A	C	rs2075401	23648065	8.83E-05	Allelic model	2.46	[1.59-3.80]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2075401-G	Research Support, Non-U.S. Gov't
5	58713680	rs2547917	G	A	rs2547917	23648065	3.00E-06	Recessive model	2	[1.35-2.96]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2547917-A	Research Support, Non-U.S. Gov't
5	58721609	rs2607347	T	C	rs2607347	23648065	9.97E-06	Recessive model	1.87	[1.26-2.77]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2607347-G	Research Support, Non-U.S. Gov't
5	68038077	rs12516844	T	G	rs12516844	23648065	3.51E-05	Dominant model	2.47	[1.47-4.17]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12516844-T	Research Support, Non-U.S. Gov't
5	72995398	rs17552357	C	T	rs17552357	23648065	9.89E-05	Allelic model	2.23	[1.47-3.37]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs17552357-T	Research Support, Non-U.S. Gov't
5	73016810	rs16870743	A	G	rs16870743	23648065	1.51E-05	Dominant model	9.52	[2.31-39.17]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs16870743-T	Research Support, Non-U.S. Gov't
5	75623689	rs2913251	A	G	rs2913251	23648065	5.19E-05	Allelic model	1.77	[1.34-2.34]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2913251-T	Research Support, Non-U.S. Gov't
5	75632745	rs2913248	G	A	rs2913248	23648065	2.61E-05	Allelic model	1.85	[1.39-2.46]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2913248-G	Research Support, Non-U.S. Gov't
5	75871279	rs3756514	G	T	rs3756514	23648065	3.68E-05	Allelic model	1.68	[1.31-2.14]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs3756514-T	Research Support, Non-U.S. Gov't
5	75874655	rs17680811	T	C	rs17680811	23648065	4.56E-05	Recessive model	1.63	[1.28-2.08]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs17680811-G	Research Support, Non-U.S. Gov't
5	75875629	rs17748322	T	C	rs17748322	23648065	8.46E-05	Allelic model	1.64	[1.28-2.10]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs17748322-C	Research Support, Non-U.S. Gov't
5	75890020	rs1501788	C	T	rs1501788	23648065	5.78E-05	Recessive model	1.57	[1.23-2.00]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1501788-A	Research Support, Non-U.S. Gov't
5	79401417	rs421837	T	C	rs421837	23648065	2.28E-05	Dominant model	1.98	[1.41-2.80]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs421837-T	Research Support, Non-U.S. Gov't
5	79888450	rs2405867	G	A	rs2405867	23648065	2.22E-05	Dominant model	1.7	[1.21-2.38]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2405867-G	Research Support, Non-U.S. Gov't
5	79952034	rs380691	A	G	rs380691	23648065	5.52E-05	Dominant model	1.57	[1.12-2.21]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs380691-T	Research Support, Non-U.S. Gov't
5	79966029	rs1805355	G	A	rs1805355	23648065	3.04E-05	Recessive model	1.72	[1.20-2.46]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1805355-G	Research Support, Non-U.S. Gov't
5	80008704	rs1428030	T	C	rs1428030	23648065	4.94E-05	Recessive model	1.73	[1.20-2.49]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1428030-T	Research Support, Non-U.S. Gov't
5	80080681	rs6151826	A	G	rs6151826	23648065	2.47E-05	Recessive model	1.66	[1.15-2.40]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6151826-T	Research Support, Non-U.S. Gov't
5	80168005	rs16878204	T	C	rs16878204	23648065	2.57E-05	Recessive model	1.75	[1.22-2.53]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs16878204-T	Research Support, Non-U.S. Gov't
5	80187929	rs12522063	T	G	rs12522063	23648065	4.22E-05	Recessive model	1.74	[1.20-2.51]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12522063-T	Research Support, Non-U.S. Gov't
5	80201284	rs6864713	G	A	rs6864713	23648065	7.11E-05	Recessive model	1.72	[1.19-2.48]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6864713-C	Research Support, Non-U.S. Gov't
5	85687037	rs10059045	A	C	rs10059045	23648065	7.35E-05	Dominant model	1.39	[1.11-1.75]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10059045-A	Research Support, Non-U.S. Gov't
5	85746871	rs1500258	A	G	rs1500258	23648065	2.85E-05	Recessive model	1.38	[1.10-1.74]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1500258-C	Research Support, Non-U.S. Gov't
5	85764555	rs1553241	A	C	rs1553241	23648065	5.35E-05	Dominant model	1.43	[1.14-1.79]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1553241-C	Research Support, Non-U.S. Gov't
5	86727027	rs7702514	C	T	rs7702514	23648065	2.16E-05	Allelic model	3.46	[1.92-6.26]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7702514-A	Research Support, Non-U.S. Gov't
5	92110386	rs258959	C	T	rs258959	23648065	9.17E-05	Recessive model	1.35	NA	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs258959-A	Research Support, Non-U.S. Gov't
5	92149000	rs1429056	T	C	rs1429056	23648065	9.20E-05	Recessive model	1.44	[1.06-1.94]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1429056-G	Research Support, Non-U.S. Gov't
5	92980916	rs12186878	C	A	rs12186878	23648065	2.07E-05	Dominant model	1.81	[1.32-2.47]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12186878-G	Research Support, Non-U.S. Gov't
5	98273862	rs161937	A	G	rs161937	23648065	4.05E-05	Allelic model	2.27	[1.51-3.40]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs161937-A	Research Support, Non-U.S. Gov't
5	98644175	rs4702966	C	T	rs4702966	23648065	5.78E-05	Recessive model	2.01	[1.37-2.95]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4702966-A	Research Support, Non-U.S. Gov't
5	98802762	rs6885370	C	T	rs6885370	23648065	7.86E-05	Dominant model	4.78	[2.23-10.22]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6885370-A	Research Support, Non-U.S. Gov't
5	99959205	rs247932	C	T	rs247932	23648065	9.67E-05	Allelic model	1.44	[1.20-1.73]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs247932-G	Research Support, Non-U.S. Gov't
5	104199060	rs1632744	T	C	rs1632744	23648065	5.00E-06	Recessive model	1.39	[0.96-2.01]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1632744-T	Research Support, Non-U.S. Gov't
5	104208013	rs10074959	G	A	rs10074959	23648065	1.00E-06	Recessive model	1.52	[1.05-2.22]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10074959-T	Research Support, Non-U.S. Gov't
5	107721366	rs11240962	C	A	rs11240962	23648065	1.81E-05	Dominant model	4.47	[2.20-9.08]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11240962-T	Research Support, Non-U.S. Gov't
5	107724017	rs10035966	T	G	rs10035966	23648065	1.81E-05	Dominant model	4.47	[2.20-9.08]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10035966-G	Research Support, Non-U.S. Gov't
5	107731684	rs4634342	G	T	rs4634342	23648065	1.12E-05	Dominant model	2.48	[1.63-3.75]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4634342-C	Research Support, Non-U.S. Gov't
5	107732317	rs1122826	G	A	rs1122826	23648065	1.81E-05	Dominant model	4.47	[2.20-9.08]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1122826-A	Research Support, Non-U.S. Gov't
5	107742569	rs10455007	A	C	rs10455007	23648065	4.10E-05	Allelic model	2.21	[1.50-3.25]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10455007-A	Research Support, Non-U.S. Gov't
5	107768782	rs12187433	T	C	rs12187433	23648065	2.44E-05	Dominant model	4.57	[2.20-9.50]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12187433-G	Research Support, Non-U.S. Gov't
5	120049065	rs9285894	A	G	rs9285894	23648065	1.10E-05	Recessive model	1.27	[0.97-1.67]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9285894-G	Research Support, Non-U.S. Gov't
5	121826721	rs1000590	G	A	rs1000590	23648065	6.89E-05	Dominant model	1.68	[1.20-2.36]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1000590-A	Research Support, Non-U.S. Gov't
5	121826941	rs2407209	G	A	rs2407209	23648065	6.89E-05	Dominant model	1.68	[1.20-2.36]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2407209-T	Research Support, Non-U.S. Gov't
5	124006906	rs6895878	T	C	rs6895878	23648065	9.06E-05	Allelic model	1.85	[1.33-2.57]	150 Japanese ancestry cases; 166 Japanese ancestry controls	Japanese(316)	ALL(316)	ASN(316)	ALL(316)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6895878-C	Research Support, Non-U.S. Gov't
5	124038251	rs12513661	G	A	rs12513661	23648065	7.21E-05	Allelic model	2.52	[1.57-4.05]	150 Japanese ancestry cases; 166 Japanese ancestry controls	Japanese(316)	ALL(316)	ASN(316)	ALL(316)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12513661-T	Research Support, Non-U.S. Gov't
5	134846824	rs12374511	A	C	rs12374511	23648065	4.61E-05	Dominant model	1.38	[1.13-1.68]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12374511-C	Research Support, Non-U.S. Gov't
5	134876123	rs13356152	T	C	rs13356152	23648065	7.95E-05	Dominant model	1.42	[1.18-1.70]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs13356152-G	Research Support, Non-U.S. Gov't
5	140519166	rs246723	A	G	rs246723	23648065	9.85E-05	Allelic model	1.64	[1.28-2.09]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs246723-C	Research Support, Non-U.S. Gov't
5	140606802	rs2907320	C	T	rs2907320	23648065	2.56E-05	Allelic model	2.55	[1.66-3.92]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2907320-A	Research Support, Non-U.S. Gov't
5	140614038	rs2907309	G	A	rs2907309	23648065	2.56E-05	Allelic model	2.55	[1.66-3.92]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2907309-A	Research Support, Non-U.S. Gov't
5	140614830	rs2907308	G	A	rs2907308	23648065	2.56E-05	Allelic model	2.55	[1.66-3.92]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2907308-T	Research Support, Non-U.S. Gov't
5	140615269	rs2907307	A	G	rs2907307	23648065	2.56E-05	Allelic model	2.55	[1.66-3.92]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2907307-C	Research Support, Non-U.S. Gov't
5	140631925	rs2910337	T	G	rs2910337	23648065	2.56E-05	Allelic model	2.55	[1.66-3.92]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2910337-G	Research Support, Non-U.S. Gov't
5	142020380	rs10070885	C	T	rs10070885	23648065	6.34E-05	Allelic model	1.71	[1.31-2.23]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10070885-C	Research Support, Non-U.S. Gov't
5	146126245	rs7715375	G	A	rs7715375	23648065	4.06E-05	Dominant model	1.5	[1.21-1.87]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7715375-G	Research Support, Non-U.S. Gov't
5	149443298	rs216140	C	T	rs216140	23648065	7.00E-05	Recessive model	1.77	[1.12-2.81]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs216140-A	Research Support, Non-U.S. Gov't
5	150967836	rs766206	C	T	rs766206	23648065	4.17E-05	Dominant model	2.15	[1.45-3.19]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs766206-A	Research Support, Non-U.S. Gov't
5	158418490	rs10447210	C	T	rs10447210	23648065	7.75E-06	Recessive model	1.45	[1.11-1.89]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10447210-G	Research Support, Non-U.S. Gov't
5	158424391	rs10040979	G	A	rs10040979	23648065	5.00E-07	Recessive model	1.45	[1.12-1.88]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10040979-G	Research Support, Non-U.S. Gov't
5	158459721	rs7720283	T	C	rs7720283	23648065	4.15E-06	Recessive model	1.43	[1.08-1.90]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7720283-C	Research Support, Non-U.S. Gov't
5	158658012	rs10515778	A	G	rs10515778	23648065	8.07E-05	Allelic model	3.95	[1.74-8.96]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10515778-T	Research Support, Non-U.S. Gov't
5	159001299	rs4315909	A	G	rs4315909	23648065	2.81E-05	Recessive model	2	[1.30-3.08]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4315909-G	Research Support, Non-U.S. Gov't
5	159870611	rs4921283	G	A	rs4921283	23648065	3.73E-05	Allelic model	2.52	[1.62-3.94]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4921283-G	Research Support, Non-U.S. Gov't
5	160689448	rs173564	T	C	rs173564	23648065	5.31E-05	Allelic model	2.21	[1.49-3.27]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs173564-C	Research Support, Non-U.S. Gov't
5	166268258	rs12656909	C	A	rs12656909	23648065	2.73E-05	Dominant model	2.41	[1.55-3.76]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12656909-C	Research Support, Non-U.S. Gov't
5	167051620	rs17068860	A	G	rs17068860	23648065	6.69E-05	Allelic model	1.82	[1.36-2.45]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs17068860-T	Research Support, Non-U.S. Gov't
5	167147874	rs10057680	A	G	rs10057680	23648065	7.95E-05	Allelic model	2.19	[1.48-3.26]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10057680-T	Research Support, Non-U.S. Gov't
5	168170445	rs10462978	T	C	rs10462978	23648065	1.80E-05	Dominant model	2.19	[1.51-3.17]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10462978-A	Research Support, Non-U.S. Gov't
5	168847968	rs13177680	A	C	rs13177680	23648065	7.87E-05	Allelic model	6.82	[2.09-22.23]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs13177680-T	Research Support, Non-U.S. Gov't
5	169538372	rs4867918	G	A	rs4867918	23648065	3.78E-05	Recessive model	1.29	[1.09-1.52]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4867918-C	Research Support, Non-U.S. Gov't
5	169540547	rs12653012	G	A	rs12653012	23648065	4.22E-05	Recessive model	1.29	[1.09-1.53]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12653012-G	Research Support, Non-U.S. Gov't
5	169542600	rs1895302	C	T	rs1895302	23648065	7.00E-06	Dominant model	1.34	[1.13-1.59]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1895302-C	Research Support, Non-U.S. Gov't
5	169551625	rs4867922	C	T	rs4867922	23648065	1.36E-05	Dominant model	1.31	[1.10-1.55]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4867922-C	Research Support, Non-U.S. Gov't
5	172269595	rs792978	C	T	rs792978	23648065	1.69E-05	Allelic model	1.69	[1.33-2.15]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs792978-G	Research Support, Non-U.S. Gov't
5	172271007	rs792975	A	G	rs792975	23648065	8.00E-06	Allelic model	1.75	[1.37-2.23]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs792975-T	Research Support, Non-U.S. Gov't
5	172272207	rs792969	T	C	rs792969	23648065	9.94E-06	Allelic model	1.74	[1.36-2.22]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs792969-G	Research Support, Non-U.S. Gov't
5	172272571	rs710109	G	A	rs710109	23648065	1.74E-05	Allelic model	1.72	[1.34-2.19]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs710109-C	Research Support, Non-U.S. Gov't
5	172272571	rs710109	G	A	rs710109	23648065	6.66E-05	Dominant model	1.4	[1.17-1.67]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs710109-C	Research Support, Non-U.S. Gov't
5	173625154	rs6863418	T	C	rs6863418	23648065	7.00E-06	Dominant model	3.62	[2.04-6.43]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6863418-A	Research Support, Non-U.S. Gov't
5	175980113	rs4868648	T	C	rs4868648	23648065	3.62E-05	Dominant model	1.53	[1.19-1.97]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4868648-T	Research Support, Non-U.S. Gov't
5	176011264	rs752139	T	C	rs752139	23648065	7.65E-05	Dominant model	1.5	[1.15-1.94]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs752139-A	Research Support, Non-U.S. Gov't
6	477738	rs7750350	C	T	rs7750350	23648065	7.45E-05	Dominant model	1.56	[1.22-1.99]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7750350-G	Research Support, Non-U.S. Gov't
6	3837198	rs17318866	G	A	rs17318866	23648065	1.00E-06	Allelic model	7.56	[2.69-21.26]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs17318866-G	Research Support, Non-U.S. Gov't
6	8945690	rs9406226	G	A	rs9406226	23648065	5.69E-05	Dominant model	1.84	[1.30-2.61]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9406226-C	Research Support, Non-U.S. Gov't
6	15215150	rs12664987	C	T	rs12664987	23648065	5.95E-05	Allelic model	1.9	[1.39-2.59]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12664987-C	Research Support, Non-U.S. Gov't
6	21259328	rs6935795	G	T	rs6935795	23648065	5.97E-05	Recessive model	1.43	[1.12-1.83]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6935795-G	Research Support, Non-U.S. Gov't
6	22046317	rs1736512	A	G	rs1736512	23648065	1.10E-05	Recessive model	1.88	[1.22-2.91]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1736512-T	Research Support, Non-U.S. Gov't
6	22046317	rs1736512	A	G	rs1736512	23648065	2.95E-05	Recessive model	1.49	[1.08-2.06]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1736512-T	Research Support, Non-U.S. Gov't
6	28466442	rs12661782	A	G	rs12661782	23648065	3.07E-05	Allelic model	2.53	[1.64-3.90]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12661782-C	Research Support, Non-U.S. Gov't
6	28473325	rs2071966	T	G	rs2071966	23648065	3.07E-05	Allelic model	2.53	[1.64-3.90]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2071966-C	Research Support, Non-U.S. Gov't
6	28500235	rs769189	T	C	rs769189	23648065	5.21E-05	Allelic model	2.44	[1.58-3.76]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs769189-C	Research Support, Non-U.S. Gov't
6	32914613	rs194682	C	T	rs194682	23648065	7.58E-05	Recessive model	1.46	[1.14-1.87]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs194682-T	Research Support, Non-U.S. Gov't
6	32932150	rs206783	C	A	rs206783	23648065	5.94E-05	Recessive model	1.48	[1.15-1.89]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs206783-T	Research Support, Non-U.S. Gov't
6	32935179	rs206786	A	C	rs206786	23648065	5.94E-05	Recessive model	1.48	[1.15-1.89]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs206786-C	Research Support, Non-U.S. Gov't
6	41296090	rs9471566	C	A	rs9471566	23648065	2.45E-05	Dominant model	1.68	[1.30-2.16]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9471566-T	Research Support, Non-U.S. Gov't
6	42025318	rs12208813	G	A	rs12208813	23648065	7.37E-05	Allelic model	3.25	[1.74-6.09]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12208813-C	Research Support, Non-U.S. Gov't
6	42037167	rs12194513	C	T	rs12194513	23648065	7.37E-05	Allelic model	3.25	[1.74-6.09]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12194513-C	Research Support, Non-U.S. Gov't
6	43882612	rs9472153	G	A	rs9472153	23648065	1.28E-05	Dominant model	1.62	[1.23-2.12]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9472153-C	Research Support, Non-U.S. Gov't
6	44051221	rs6458368	T	C	rs6458368	23648065	8.63E-05	Allelic model	1.88	[1.38-2.57]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6458368-A	Research Support, Non-U.S. Gov't
6	44081718	rs6883	G	A	rs6883	23648065	7.33E-05	Dominant model	1.79	[1.34-2.41]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6883-G	Research Support, Non-U.S. Gov't
6	44191920	rs693955	A	C	rs693955	23648065	5.65E-05	Dominant model	2.85	[1.64-4.95]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs693955-C	Research Support, Non-U.S. Gov't
6	47187915	rs4629675	T	C	rs4629675	23648065	6.52E-05	Recessive model	1.42	[1.11-1.83]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4629675-T	Research Support, Non-U.S. Gov't
6	50522228	rs984329	C	T	rs984329	23648065	1.27E-05	Allelic model	1.74	[1.36-2.22]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs984329-T	Research Support, Non-U.S. Gov't
6	50522228	rs984329	C	T	rs984329	23648065	3.42E-05	Allelic model	1.43	[1.21-1.69]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs984329-T	Research Support, Non-U.S. Gov't
6	50528436	rs280344	T	C	rs280344	23648065	3.40E-05	Allelic model	1.68	[1.32-2.15]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs280344-G	Research Support, Non-U.S. Gov't
6	50548918	rs9367402	C	T	rs9367402	23648065	1.25E-05	Allelic model	1.74	[1.36-2.23]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9367402-A	Research Support, Non-U.S. Gov't
6	50548918	rs9367402	C	T	rs9367402	23648065	2.88E-05	Allelic model	1.44	[1.21-1.70]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9367402-A	Research Support, Non-U.S. Gov't
6	50576468	rs1161444	C	T	rs1161444	23648065	4.36E-05	Allelic model	1.68	[1.31-2.15]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1161444-A	Research Support, Non-U.S. Gov't
6	51572515	rs9395707	G	A	rs9395707	23648065	6.10E-05	Allelic model	2.05	[1.44-2.93]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9395707-A	Research Support, Non-U.S. Gov't
6	54310853	rs243799	C	T	rs243799	23648065	1.87E-05	Dominant model	2.11	[1.48-3.00]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs243799-C	Research Support, Non-U.S. Gov't
6	54424937	rs6459009	T	G	rs6459009	23648065	3.32E-05	Dominant model	1.9	[1.36-2.68]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6459009-G	Research Support, Non-U.S. Gov't
6	54441359	rs1853335	G	A	rs1853335	23648065	5.86E-05	Dominant model	1.96	[1.39-2.76]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1853335-A	Research Support, Non-U.S. Gov't
6	66106319	rs9453294	T	C	rs9453294	23648065	3.46E-05	Recessive model	1.69	[1.08-2.65]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9453294-A	Research Support, Non-U.S. Gov't
6	66112409	rs974110	A	G	rs974110	23648065	3.46E-05	Recessive model	1.69	[1.08-2.65]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs974110-T	Research Support, Non-U.S. Gov't
6	73740864	rs10498887	G	A,C	rs10498887	23648065	5.09E-05	Dominant model	2.17	[1.41-3.35]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10498887-G	Research Support, Non-U.S. Gov't
6	77266188	rs4235898	G	A	rs4235898	23648065	1.00E-06	Allelic model	1.72	[1.38-2.14]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4235898-A	Research Support, Non-U.S. Gov't
6	78531689	rs9359294	A	G	rs9359294	23648065	8.61E-05	Allelic model	2.1	[1.45-3.04]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9359294-T	Research Support, Non-U.S. Gov't
6	80512765	rs9448824	G	T	rs9448824	23648065	4.25E-05	Dominant model	2.27	[1.42-3.62]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9448824-C	Research Support, Non-U.S. Gov't
6	82496434	rs194615	T	C	rs194615	23648065	8.76E-05	Dominant model	2.51	[1.54-4.08]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs194615-C	Research Support, Non-U.S. Gov't
6	90465626	rs6942026	T	G	rs6942026	23648065	4.39E-05	Dominant model	2.9	[1.57-5.34]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6942026-C	Research Support, Non-U.S. Gov't
6	95202197	rs1022787	G	A	rs1022787	23648065	9.44E-05	Allelic model	1.64	[1.28-2.10]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1022787-G	Research Support, Non-U.S. Gov't
6	96008082	rs7748108	T	C	rs7748108	23648065	7.66E-05	Dominant model	3.47	[1.59-7.54]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7748108-C	Research Support, Non-U.S. Gov't
6	98361795	rs6934784	A	C	rs6934784	23648065	3.31E-05	Allelic model	1.68	[1.32-2.14]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6934784-C	Research Support, Non-U.S. Gov't
6	98379027	rs6940021	G	A	rs6940021	23648065	3.40E-05	Allelic model	1.67	[1.31-2.13]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6940021-A	Research Support, Non-U.S. Gov't
6	98470233	rs17813462	T	C	rs17813462	23648065	4.49E-05	Allelic model	1.83	[1.38-2.44]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs17813462-C	Research Support, Non-U.S. Gov't
6	98489654	rs4839936	C	T	rs4839936	23648065	1.03E-05	Allelic model	1.75	[1.37-2.23]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4839936-T	Research Support, Non-U.S. Gov't
6	98495952	rs2505059	A	G	rs2505059	23648065	5.00E-06	Allelic model	1.77	[1.38-2.25]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2505059-G	Research Support, Non-U.S. Gov't
6	98560826	rs1906251	C	A	rs1906251	23648065	9.48E-06	Allelic model	1.74	[1.37-2.22]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1906251-C	Research Support, Non-U.S. Gov't
6	98597689	rs1487452	C	T	rs1487452	23648065	7.61E-06	Allelic model	1.75	[1.37-2.23]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1487452-T	Research Support, Non-U.S. Gov't
6	98626561	rs9372752	G	A	rs9372752	23648065	1.68E-05	Allelic model	1.72	[1.34-2.19]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9372752-G	Research Support, Non-U.S. Gov't
6	98634277	rs2505081	C	T	rs2505081	23648065	6.95E-05	Allelic model	1.64	[1.29-2.10]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2505081-G	Research Support, Non-U.S. Gov't
6	98652595	rs1376499	C	A	rs1376499	23648065	2.25E-05	Allelic model	1.7	[1.33-2.17]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1376499-C	Research Support, Non-U.S. Gov't
6	101976291	rs2518251	T	G	rs2518251	23648065	6.92E-05	Recessive model	1.63	[1.15-2.29]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2518251-G	Research Support, Non-U.S. Gov't
6	105757070	rs1617445	C	T	rs1617445	23648065	6.33E-05	Allelic model	2.29	[1.50-3.48]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1617445-G	Research Support, Non-U.S. Gov't
6	106329055	rs9386485	C	T	rs9386485	23648065	1.00E-06	Allelic model	1.82	[1.43-2.32]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9386485-T	Research Support, Non-U.S. Gov't
6	106329055	rs9386485	C	T	rs9386485	23648065	3.00E-06	Allelic model	1.52	[1.28-1.82]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9386485-T	Research Support, Non-U.S. Gov't
6	118117246	rs11755280	T	C	rs11755280	23648065	9.09E-05	Dominant model	1.35	[1.12-1.63]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11755280-A	Research Support, Non-U.S. Gov't
6	120284989	rs9401193	A	C	rs9401193	23648065	3.23E-05	Dominant model	2.89	[1.68-4.97]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9401193-C	Research Support, Non-U.S. Gov't
6	124681503	rs12204812	C	A	rs12204812	23648065	4.16E-05	Dominant model	5.51	[2.18-13.93]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12204812-T	Research Support, Non-U.S. Gov't
6	124681503	rs12204812	C	A	rs12204812	23648065	5.69E-05	Dominant model	2.33	[1.52-3.56]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12204812-T	Research Support, Non-U.S. Gov't
6	124688755	rs911959	T	C	rs911959	23648065	3.97E-05	Allelic model	8.75	[2.55-29.98]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs911959-G	Research Support, Non-U.S. Gov't
6	129673689	rs9385488	T	C	rs9385488	23648065	5.47E-05	Allelic model	3.83	[1.94-7.60]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9385488-C	Research Support, Non-U.S. Gov't
6	129674757	rs3813367	G	T	rs3813367	23648065	5.09E-05	Allelic model	4.13	[1.98-8.61]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs3813367-A	Research Support, Non-U.S. Gov't
6	129700998	rs17057200	C	T	rs17057200	23648065	5.09E-05	Allelic model	4.13	[1.98-8.61]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs17057200-T	Research Support, Non-U.S. Gov't
6	130005667	rs6920979	G	T	rs6920979	23648065	8.50E-06	Dominant model	2.34	[1.59-3.44]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6920979-C	Research Support, Non-U.S. Gov't
6	130008445	rs12660691	A	C	rs12660691	23648065	4.00E-06	Allelic model	3.2	[1.90-5.39]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12660691-A	Research Support, Non-U.S. Gov't
6	130021128	rs2157460	A	G	rs2157460	23648065	7.07E-06	Allelic model	3.01	[1.81-5.03]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2157460-T	Research Support, Non-U.S. Gov't
6	130029839	rs2068685	G	A	rs2068685	23648065	8.90E-06	Allelic model	2.94	[1.78-4.85]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2068685-G	Research Support, Non-U.S. Gov't
6	141428255	rs9389870	T	C	rs9389870	23648065	7.81E-05	Allelic model	1.95	[1.40-2.71]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9389870-T	Research Support, Non-U.S. Gov't
6	142093922	rs9496139	A	G	rs9496139	23648065	7.02E-05	Allelic model	2.44	[1.59-3.75]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9496139-C	Research Support, Non-U.S. Gov't
6	147326634	rs1406537	C	T	rs1406537	23648065	7.45E-05	Dominant model	1.61	[1.20-2.17]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1406537-A	Research Support, Non-U.S. Gov't
6	147366538	rs11969474	T	C	rs11969474	23648065	8.24E-05	Allelic model	2.72	[1.64-4.53]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11969474-A	Research Support, Non-U.S. Gov't
6	147368934	rs6907758	C	T	rs6907758	23648065	8.24E-05	Allelic model	2.72	[1.64-4.53]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6907758-C	Research Support, Non-U.S. Gov't
6	147409180	rs12664682	G	A	rs12664682	23648065	3.88E-05	Allelic model	3.13	[1.78-5.51]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12664682-C	Research Support, Non-U.S. Gov't
6	147409235	rs12661753	A	G	rs12661753	23648065	3.88E-05	Allelic model	3.13	[1.78-5.51]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12661753-A	Research Support, Non-U.S. Gov't
6	147414032	rs7771711	G	A	rs7771711	23648065	3.88E-05	Allelic model	3.13	[1.78-5.51]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7771711-G	Research Support, Non-U.S. Gov't
6	147635547	rs1039085	C	T	rs1039085	23648065	5.39E-05	Allelic model	2	[1.42-2.82]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1039085-G	Research Support, Non-U.S. Gov't
6	152229850	rs2347867	G	A	rs2347867	23648065	3.14E-05	Allelic model	1.79	[1.37-2.34]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2347867-A	Research Support, Non-U.S. Gov't
6	156582195	rs12661043	T	C	rs12661043	23648065	5.09E-05	Allelic model	1.89	[1.36-2.60]	150 Japanese ancestry cases; 166 Japanese ancestry controls	Japanese(316)	ALL(316)	ASN(316)	ALL(316)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12661043-T	Research Support, Non-U.S. Gov't
6	157265752	rs10485203	T	C	rs10485203	23648065	7.94E-05	Dominant model	1.48	[1.20-1.84]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10485203-T	Research Support, Non-U.S. Gov't
6	158689753	rs9355613	T	C	rs9355613	23648065	9.89E-05	Allelic model	1.64	[1.28-2.10]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9355613-G	Research Support, Non-U.S. Gov't
6	161988513	rs9456684	G	A	rs9456684	23648065	3.79E-05	Allelic model	2.21	[1.52-3.20]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9456684-G	Research Support, Non-U.S. Gov't
6	161988767	rs9355351	A	G	rs9355351	23648065	5.53E-05	Allelic model	2.18	[1.50-3.16]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9355351-T	Research Support, Non-U.S. Gov't
6	161989903	rs885782	A	C	rs885782	23648065	1.07E-05	Recessive model	2.17	[1.51-3.14]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs885782-T	Research Support, Non-U.S. Gov't
6	162006836	rs9364605	C	T	rs9364605	23648065	2.16E-05	Allelic model	2.24	[1.54-3.26]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9364605-C	Research Support, Non-U.S. Gov't
6	162575299	rs869298	C	T	rs869298	23648065	5.27E-05	Dominant model	2.06	[1.46-2.90]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs869298-G	Research Support, Non-U.S. Gov't
6	162577258	rs2849609	C	T	rs2849609	23648065	1.92E-05	Dominant model	1.71	[1.34-2.18]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2849609-C	Research Support, Non-U.S. Gov't
6	162577258	rs2849609	C	T	rs2849609	23648065	3.08E-05	Dominant model	2	[1.46-2.75]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2849609-C	Research Support, Non-U.S. Gov't
6	167398071	rs394522	A	C	rs394522	23648065	5.81E-05	Recessive model	1.38	[1.10-1.74]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs394522-C	Research Support, Non-U.S. Gov't
6	167398071	rs394522	A	C	rs394522	23648065	8.97E-05	Recessive model	1.28	[1.08-1.52]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs394522-C	Research Support, Non-U.S. Gov't
6	170347127	rs1466749	G	A	rs1466749	23648065	7.57E-05	Allelic model	1.99	[1.41-2.80]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1466749-A	Research Support, Non-U.S. Gov't
7	5396955	rs7805732	A	G	rs7805732	23648065	5.93E-05	Dominant model	1.61	[1.23-2.11]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7805732-G	Research Support, Non-U.S. Gov't
7	9247266	rs4720829	T	C	rs4720829	23648065	2.70E-05	Dominant model	1.6	[1.24-2.06]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4720829-A	Research Support, Non-U.S. Gov't
7	11677126	rs12154996	A	G	rs12154996	23648065	4.45E-05	Allelic model	2.51	[1.62-3.87]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12154996-G	Research Support, Non-U.S. Gov't
7	12094966	rs1035147	A	C	rs1035147	23648065	4.00E-06	Allelic model	7.29	[2.59-20.56]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1035147-T	Research Support, Non-U.S. Gov't
7	12708504	rs13226473	A	G	rs13226473	23648065	3.36E-05	Allelic model	2.03	[1.47-2.79]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs13226473-G	Research Support, Non-U.S. Gov't
7	12713070	rs10488226	G	T	rs10488226	23648065	3.00E-06	Dominant model	2.03	[1.50-2.74]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10488226-A	Research Support, Non-U.S. Gov't
7	13238496	rs16877717	G	A	rs16877717	23648065	1.85E-05	Recessive model	1.85	[1.17-2.91]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs16877717-T	Research Support, Non-U.S. Gov't
7	16861849	rs10253216	G	A	rs10253216	23648065	2.00E-07	Dominant model	1.48	[1.16-1.89]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10253216-T	Research Support, Non-U.S. Gov't
7	16862235	rs7797977	G	T	rs7797977	23648065	2.17E-06	Recessive model	1.46	[1.13-1.88]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7797977-C	Research Support, Non-U.S. Gov't
7	16863727	rs11768848	C	A	rs11768848	23648065	2.16E-06	Recessive model	1.46	[1.13-1.89]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11768848-C	Research Support, Non-U.S. Gov't
7	16878113	rs10232481	T	G	rs10232481	23648065	3.47E-07	Dominant model	1.49	[1.16-1.90]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10232481-C	Research Support, Non-U.S. Gov't
7	16882053	rs1404966	A	G	rs1404966	23648065	5.58E-06	Dominant model	1.45	[1.13-1.85]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1404966-G	Research Support, Non-U.S. Gov't
7	16884241	rs17136737	T	G	rs17136737	23648065	4.90E-06	Dominant model	1.46	[1.15-1.87]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs17136737-C	Research Support, Non-U.S. Gov't
7	16884241	rs17136737	T	G	rs17136737	23648065	8.73E-05	Dominant model	1.3	[1.10-1.54]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs17136737-C	Research Support, Non-U.S. Gov't
7	17085321	rs6961860	C	T	rs6961860	23648065	5.00E-06	Recessive model	1.28	[1.08-1.53]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6961860-G	Research Support, Non-U.S. Gov't
7	17277084	rs1476079	C	A	rs1476079	23648065	7.43E-05	Recessive model	1.48	[1.17-1.86]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1476079-A	Research Support, Non-U.S. Gov't
7	19371245	rs9654950	A	G	rs9654950	23648065	2.42E-05	Recessive model	1.99	[1.28-3.08]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9654950-G	Research Support, Non-U.S. Gov't
7	20255705	rs3095008	G	A	rs3095008	23648065	9.00E-06	Dominant model	NA	NA	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs3095008-T	Research Support, Non-U.S. Gov't
7	21980773	rs6946675	A	C	rs6946675	23648065	5.81E-05	Allelic model	1.73	[1.32-2.25]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6946675-T	Research Support, Non-U.S. Gov't
7	26191698	rs2073536	T	C	rs2073536	23648065	9.86E-05	Recessive model	1.54	[1.14-2.07]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2073536-C	Research Support, Non-U.S. Gov't
7	32255322	rs4723134	C	T	rs4723134	23648065	9.09E-05	Allelic model	1.97	[1.41-2.74]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4723134-A	Research Support, Non-U.S. Gov't
7	34178283	rs12673452	G	A	rs12673452	23648065	1.61E-05	Allelic model	4.27	[2.16-8.42]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12673452-A	Research Support, Non-U.S. Gov't
7	34405042	rs17169771	A	G	rs17169771	23648065	4.68E-05	Recessive model	1.38	[1.09-1.74]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs17169771-A	Research Support, Non-U.S. Gov't
7	34407843	rs10280909	A	G	rs10280909	23648065	4.71E-05	Recessive model	1.37	[1.08-1.74]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10280909-A	Research Support, Non-U.S. Gov't
7	37562368	rs1425132	A	G	rs1425132	23648065	5.00E-06	Recessive model	1.43	[1.01-2.02]	150 Japanese ancestry cases; 166 Japanese ancestry controls	Japanese(316)	ALL(316)	ASN(316)	ALL(316)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1425132-T	Research Support, Non-U.S. Gov't
7	39304125	rs4302750	A	G	rs4302750	23648065	9.89E-05	Dominant model	1.64	[1.27-2.11]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4302750-G	Research Support, Non-U.S. Gov't
7	43506158	rs2304328	T	C	rs2304328	23648065	8.17E-05	Recessive model	1.38	[1.09-1.75]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2304328-G	Research Support, Non-U.S. Gov't
7	45554986	rs7793106	A	G	rs7793106	23648065	5.27E-05	Dominant model	2.4	[1.54-3.73]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7793106-C	Research Support, Non-U.S. Gov't
7	47432669	rs2470996	A	C	rs2470996	23648065	2.45E-05	Recessive model	1.75	[1.23-2.48]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2470996-T	Research Support, Non-U.S. Gov't
7	50243488	rs1037676	A	C	rs1037676	23648065	5.76E-05	Allelic model	4.89	[1.95-12.26]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1037676-A	Research Support, Non-U.S. Gov't
7	50249013	rs11761913	C	T	rs11761913	23648065	1.26E-05	Allelic model	2.06	[1.48-2.86]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11761913-A	Research Support, Non-U.S. Gov't
7	50249013	rs11761913	C	T	rs11761913	23648065	5.57E-05	Allelic model	2.42	[1.56-3.77]	150 Japanese ancestry cases; 166 Japanese ancestry controls	Japanese(316)	ALL(316)	ASN(316)	ALL(316)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11761913-A	Research Support, Non-U.S. Gov't
7	50460096	rs6964823	G	A	rs6964823	23648065	2.45E-05	Recessive model	1.25	[1.00-1.56]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6964823-A	Research Support, Non-U.S. Gov't
7	50476139	rs12719019	C	T	rs12719019	23648065	5.19E-05	Recessive model	1.18	[0.94-1.47]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12719019-T	Research Support, Non-U.S. Gov't
7	54976715	rs10277377	C	T	rs10277377	23648065	2.38E-05	Allelic model	2.5	[1.64-3.81]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10277377-T	Research Support, Non-U.S. Gov't
7	55169291	rs4947491	A	G	rs4947491	23648065	9.76E-05	Dominant model	2.35	[1.41-3.94]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4947491-C	Research Support, Non-U.S. Gov't
7	81225029	rs2098560	C	T	rs2098560	23648065	8.14E-05	Dominant model	3.99	[1.99-8.00]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2098560-G	Research Support, Non-U.S. Gov't
7	89635741	rs10259230	T	C	rs10259230	23648065	8.74E-05	Recessive model	1.56	[1.04-2.34]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10259230-C	Research Support, Non-U.S. Gov't
7	91680974	rs10275125	G	A	rs10275125	23648065	9.15E-05	Allelic model	4.2	[2.04-8.65]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10275125-T	Research Support, Non-U.S. Gov't
7	91691070	rs2961024	G	T	rs2961024	23648065	9.15E-05	Allelic model	4.2	[2.04-8.65]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2961024-T	Research Support, Non-U.S. Gov't
7	91736464	rs12538678	T	G	rs12538678	23648065	4.78E-05	Allelic model	4.43	[2.15-9.12]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12538678-G	Research Support, Non-U.S. Gov't
7	91892459	rs17164470	A	G	rs17164470	23648065	3.91E-05	Allelic model	4.94	[2.27-10.73]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs17164470-T	Research Support, Non-U.S. Gov't
7	92031948	rs38795	G	A	rs38795	23648065	4.55E-05	Allelic model	4.38	[2.12-9.05]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs38795-G	Research Support, Non-U.S. Gov't
7	93787413	rs7357193	C	A	rs7357193	23648065	3.01E-05	Recessive model	1.34	[1.12-1.62]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7357193-T	Research Support, Non-U.S. Gov't
7	93930713	rs12704714	C	T	rs12704714	23648065	7.88E-05	Dominant model	1.66	[1.27-2.17]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12704714-G	Research Support, Non-U.S. Gov't
7	97425721	rs1229568	C	T	rs1229568	23648065	9.68E-05	Recessive model	1.5	[1.00-2.25]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1229568-A	Research Support, Non-U.S. Gov't
7	97432533	rs1229553	T	C	rs1229553	23648065	9.68E-05	Recessive model	1.5	[1.00-2.25]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1229553-C	Research Support, Non-U.S. Gov't
7	97854393	rs2291745	G	A	rs2291745	23648065	2.16E-05	Allelic model	2.24	[1.54-3.26]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2291745-A	Research Support, Non-U.S. Gov't
7	97863145	rs2291750	G	A	rs2291750	23648065	2.16E-05	Allelic model	2.24	[1.54-3.26]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2291750-A	Research Support, Non-U.S. Gov't
7	106398153	rs10953517	G	A	rs10953517	23648065	7.73E-05	Dominant model	2.2	[1.43-3.40]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10953517-C	Research Support, Non-U.S. Gov't
7	107968803	rs2267887	G	A	rs2267887	23648065	9.09E-05	Dominant model	1.43	[1.05-1.94]	150 Japanese ancestry cases; 166 Japanese ancestry controls	Japanese(316)	ALL(316)	ASN(316)	ALL(316)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2267887-T	Research Support, Non-U.S. Gov't
7	122696223	rs1404838	T	C	rs1404838	23648065	7.69E-06	Dominant model	2.07	[1.49-2.88]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1404838-A	Research Support, Non-U.S. Gov't
7	122759980	rs4727963	C	T	rs4727963	23648065	1.00E-06	Dominant model	2.09	[1.50-2.91]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4727963-C	Research Support, Non-U.S. Gov't
7	122766907	rs2204292	C	T	rs2204292	23648065	1.04E-06	Dominant model	2.09	[1.50-2.91]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2204292-T	Research Support, Non-U.S. Gov't
7	122785428	rs2470975	A	G	rs2470975	23648065	5.29E-06	Dominant model	2	[1.44-2.79]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2470975-G	Research Support, Non-U.S. Gov't
7	122790213	rs2462150	C	G	rs2462150	23648065	3.27E-06	Dominant model	2.02	[1.45-2.81]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2462150-G	Research Support, Non-U.S. Gov't
7	130696720	rs1588769	C	T	rs1588769	23648065	8.07E-05	Recessive model	1.18	[0.89-1.57]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1588769-A	Research Support, Non-U.S. Gov't
7	131334612	rs199973478	T	TC	rs2909679	23648065	5.74E-05	Recessive model	1.4	[1.16-1.68]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2909679-C	Research Support, Non-U.S. Gov't
7	131334612	rs2909679	T	C	rs2909679	23648065	5.74E-05	Recessive model	1.4	[1.16-1.68]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2909679-C	Research Support, Non-U.S. Gov't
7	136339058	rs10435421	C	T	rs10435421	23648065	7.57E-05	Allelic model	4.53	[2.03-10.09]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10435421-C	Research Support, Non-U.S. Gov't
7	146751635	rs10266239	G	A	rs10266239	23648065	1.08E-05	Allelic model	2.34	[1.59-3.44]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10266239-G	Research Support, Non-U.S. Gov't
7	146751635	rs10266239	G	A	rs10266239	23648065	6.76E-05	Allelic model	2.68	[1.62-4.43]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10266239-G	Research Support, Non-U.S. Gov't
7	154934501	rs4146256	C	A	rs4146256	23648065	6.66E-05	Allelic model	15.24	[2.08-111.82]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4146256-A	Research Support, Non-U.S. Gov't
7	155057997	rs4506162	A	G	rs4506162	23648065	1.27E-05	Allelic model	5.76	[2.26-14.72]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4506162-G	Research Support, Non-U.S. Gov't
7	158038989	rs10235911	C	T	rs10235911	23648065	5.91E-05	Recessive model	1.35	[1.06-1.71]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10235911-C	Research Support, Non-U.S. Gov't
8	1033625	rs2336695	A	G	rs2336695	23648065	8.16E-05	Allelic model	1.71	[1.31-2.23]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2336695-T	Research Support, Non-U.S. Gov't
8	1842729	rs3758004	C	T	rs3758004	23648065	3.28E-05	Allelic model	3.36	[1.87-6.06]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs3758004-A	Research Support, Non-U.S. Gov't
8	2064121	rs12548396	C	T	rs12548396	23648065	9.11E-05	Allelic model	1.63	[1.28-2.08]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12548396-G	Research Support, Non-U.S. Gov't
8	4060604	rs4875308	G	A	rs4875308	23648065	9.39E-05	Allelic model	1.65	[1.29-2.11]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4875308-A	Research Support, Non-U.S. Gov't
8	4105147	rs1714746	G	A	rs1714746	23648065	7.00E-06	Recessive model	1.61	[1.26-2.06]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1714746-G	Research Support, Non-U.S. Gov't
8	6323278	rs2916733	G	A	rs2916733	21799462	2.00E-09	NA	2.74	[1.96-3.83]	67 Japanese ancestry cases; 203 Japanese ancestry controls	Japanese(270)	ALL(270)	ASN(270)	ALL(270)	Epirubicin-induced leukopenia	HPOID:0001882	Leukopenia	DOID:615	leukopenia	D007970	Leukopenia	EFOID:0004233	leukopenia	Leukopenia	rs2916733-C	Research Support, Non-U.S. Gov't	T,C	MCPH1
8	6352358	rs1031309	A	C	rs1031309	23648065	4.69E-05	Dominant model	1.93	[1.35-2.76]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1031309-C	Research Support, Non-U.S. Gov't
8	9313017	rs6995907	T	C	rs6995907	23648065	6.88E-05	Dominant model	2	[1.41-2.85]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6995907-T	Research Support, Non-U.S. Gov't
8	9323515	rs10105543	C	T	rs10105543	23648065	6.56E-05	Allelic model	1.87	[1.38-2.54]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10105543-C	Research Support, Non-U.S. Gov't
8	10331754	rs9329223	A	G	rs9329223	23648065	7.02E-05	Dominant model	1.81	[1.35-2.42]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9329223-A	Research Support, Non-U.S. Gov't
8	11404514	rs7820492	G	A	rs7820492	23648065	9.01E-05	Dominant model	6.01	[2.21-16.38]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7820492-T	Research Support, Non-U.S. Gov't
8	14450366	rs1510424	A	G	rs1510424	23648065	6.75E-05	Recessive model	1.37	[1.03-1.82]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1510424-A	Research Support, Non-U.S. Gov't
8	16406371	rs12681937	G	T	rs12681937	23648065	8.67E-05	Dominant model	1.33	[1.11-1.58]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12681937-T	Research Support, Non-U.S. Gov't
8	17056651	rs2904671	G	A	rs2904671	23648065	3.26E-05	Allelic model	1.94	[1.41-2.67]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2904671-A	Research Support, Non-U.S. Gov't
8	18233582	rs7006687	C	T	rs7006687	23648065	6.63E-05	Allelic model	1.67	[1.30-2.14]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7006687-T	Research Support, Non-U.S. Gov't
8	18243603	rs10109286	T	C	rs10109286	23648065	3.33E-05	Allelic model	1.69	[1.32-2.16]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10109286-C	Research Support, Non-U.S. Gov't
8	18839091	rs1426919	A	C	rs1426919	23648065	9.51E-05	Dominant model	1.52	[1.17-1.98]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1426919-C	Research Support, Non-U.S. Gov't
8	18844382	rs10216388	C	A	rs10216388	23648065	9.87E-05	Dominant model	1.51	[1.16-1.96]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10216388-G	Research Support, Non-U.S. Gov't
8	21615817	rs11786696	C	T	rs11786696	23648065	8.26E-05	Allelic model	2.67	[1.60-4.46]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11786696-G	Research Support, Non-U.S. Gov't
8	22608029	rs11781835	A	G	rs11781835	23648065	9.16E-05	Allelic model	2.06	[1.43-2.96]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11781835-T	Research Support, Non-U.S. Gov't
8	26298209	rs11781866	T	C	rs11781866	23648065	1.11E-05	Allelic model	1.87	[1.41-2.49]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11781866-T	Research Support, Non-U.S. Gov't
8	26298209	rs11781866	T	C	rs11781866	23648065	8.16E-05	Allelic model	2.15	[1.47-3.16]	150 Japanese ancestry cases; 166 Japanese ancestry controls	Japanese(316)	ALL(316)	ASN(316)	ALL(316)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11781866-T	Research Support, Non-U.S. Gov't
8	27539370	rs559251	T	C	rs559251	23648065	1.17E-05	Dominant model	1.83	[1.35-2.49]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs559251-T	Research Support, Non-U.S. Gov't
8	27740066	rs6999359	G	A	rs6999359	23648065	1.68E-05	Dominant model	1.62	[1.26-2.10]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6999359-T	Research Support, Non-U.S. Gov't
8	27740417	rs11774576	C	T	rs11774576	23648065	3.00E-06	Dominant model	1.7	[1.31-2.21]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11774576-A	Research Support, Non-U.S. Gov't
8	27740693	rs10103507	A	G	rs10103507	23648065	4.45E-06	Dominant model	1.68	[1.29-2.19]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10103507-G	Research Support, Non-U.S. Gov't
8	29838800	rs16876298	G	A	rs16876298	23648065	1.96E-05	Dominant model	1.68	[1.24-2.27]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs16876298-C	Research Support, Non-U.S. Gov't
8	37118078	rs6468400	T	G	rs6468400	23648065	9.85E-05	Dominant model	1.5	[1.18-1.91]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6468400-A	Research Support, Non-U.S. Gov't
8	37660948	rs4976893	G	A	rs4976893	23648065	6.46E-05	Recessive model	1.35	[1.14-1.61]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4976893-C	Research Support, Non-U.S. Gov't
8	55779565	rs1396895	T	C	rs1396895	23648065	2.26E-05	Recessive model	1.49	[0.99-2.25]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1396895-T	Research Support, Non-U.S. Gov't
8	63915482	rs16930073	G	A	rs16930073	23648065	9.67E-05	Allelic model	1.46	[1.21-1.77]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs16930073-A	Research Support, Non-U.S. Gov't
8	68527890	rs900114	G	T	rs900114	23648065	6.72E-05	Dominant model	1.78	[1.29-2.45]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs900114-T	Research Support, Non-U.S. Gov't
8	69119721	rs9792403	T	C	rs9792403	23648065	4.34E-05	Recessive model	1.31	[0.92-1.87]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9792403-G	Research Support, Non-U.S. Gov't
8	69119721	rs9792403	T	C	rs9792403	23648065	6.71E-05	Recessive model	1.31	[0.84-2.06]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9792403-G	Research Support, Non-U.S. Gov't
8	71449445	rs10106858	T	C	rs10106858	23648065	9.80E-05	Recessive model	1.37	[0.92-2.05]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10106858-T	Research Support, Non-U.S. Gov't
8	71454529	rs4556114	G	A	rs4556114	23648065	9.80E-05	Recessive model	1.35	[0.90-2.02]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4556114-G	Research Support, Non-U.S. Gov't
8	73702832	rs1866739	G	A	rs1866739	23648065	6.95E-05	Allelic model	2.54	[1.59-4.07]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1866739-G	Research Support, Non-U.S. Gov't
8	74230223	rs6989495	G	T	rs6989495	23648065	1.65E-05	Recessive model	1.69	[1.31-2.19]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6989495-A	Research Support, Non-U.S. Gov't
8	74230223	rs6989495	G	T	rs6989495	23648065	6.08E-05	Recessive model	1.57	[1.22-2.01]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6989495-A	Research Support, Non-U.S. Gov't
8	98080225	rs2513399	A	C	rs2513399	23648065	5.66E-05	Allelic model	2.49	[1.59-3.89]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2513399-C	Research Support, Non-U.S. Gov't
8	98963817	rs897189	C	T	rs897189	23648065	5.58E-05	Allelic model	1.48	[1.22-1.79]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs897189-A	Research Support, Non-U.S. Gov't
8	98969239	rs2512032	T	G	rs2512032	23648065	4.78E-05	Allelic model	1.49	[1.23-1.81]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2512032-C	Research Support, Non-U.S. Gov't
8	98969239	rs2512032	T	G	rs2512032	23648065	7.93E-05	Dominant model	1.72	[1.31-2.27]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2512032-C	Research Support, Non-U.S. Gov't
8	99022009	rs2444896	C	A	rs2444896	23648065	2.00E-06	Dominant model	1.75	[1.36-2.27]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2444896-T	Research Support, Non-U.S. Gov't
8	101024505	rs7006527	A	C	rs7006527	23648065	4.57E-05	Allelic model	3.81	[2.04-7.11]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7006527-G	Research Support, Non-U.S. Gov't
8	101043237	rs11779445	T	C	rs11779445	23648065	6.11E-05	Recessive model	2.09	[1.45-3.01]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11779445-C	Research Support, Non-U.S. Gov't
8	101671221	rs7002825	T	C	rs7002825	23648065	2.95E-05	Recessive model	1.23	[1.02-1.48]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7002825-A	Research Support, Non-U.S. Gov't
8	101671221	rs7002825	T	C	rs7002825	23648065	7.44E-05	Recessive model	1.27	[0.98-1.66]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7002825-A	Research Support, Non-U.S. Gov't
8	109924310	rs12681052	C	A	rs12681052	23648065	3.66E-05	Allelic model	2.41	[1.56-3.71]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12681052-C	Research Support, Non-U.S. Gov't
8	117462506	rs13263375	T	C	rs13263375	23648065	1.81E-05	Allelic model	1.53	[1.26-1.87]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs13263375-T	Research Support, Non-U.S. Gov't
8	117462992	rs13270180	G	A	rs13270180	23648065	2.21E-05	Allelic model	1.53	[1.25-1.86]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs13270180-G	Research Support, Non-U.S. Gov't
8	121377780	rs7821312	C	T	rs7821312	23648065	3.83E-05	Allelic model	1.58	[1.27-1.95]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7821312-A	Research Support, Non-U.S. Gov't
8	121377780	rs7821312	C	T	rs7821312	23648065	4.26E-05	Allelic model	2.38	[1.56-3.63]	150 Japanese ancestry cases; 166 Japanese ancestry controls	Japanese(316)	ALL(316)	ASN(316)	ALL(316)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7821312-A	Research Support, Non-U.S. Gov't
8	121386925	rs4870728	C	T	rs4870728	23648065	5.20E-05	Allelic model	1.56	[1.26-1.92]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4870728-T	Research Support, Non-U.S. Gov't
8	126380443	rs4871589	T	C	rs4871589	23648065	5.77E-05	Dominant model	1.63	[1.23-2.15]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4871589-G	Research Support, Non-U.S. Gov't
8	135870334	rs1000394	T	C	rs1000394	23648065	8.48E-05	Recessive model	1.37	[0.92-2.04]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1000394-A	Research Support, Non-U.S. Gov't
8	135870334	rs1000394	T	C	rs1000394	23648065	9.24E-05	Recessive model	1.98	[1.23-3.19]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1000394-A	Research Support, Non-U.S. Gov't
8	136522558	rs11779943	G	A	rs11779943	23648065	6.61E-05	Recessive model	1.43	[1.00-2.06]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11779943-C	Research Support, Non-U.S. Gov't
8	136526248	rs10092358	A	G	rs10092358	23648065	6.61E-05	Recessive model	1.43	[1.00-2.06]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10092358-T	Research Support, Non-U.S. Gov't
8	136539132	rs16905387	T	G	rs16905387	23648065	4.23E-05	Recessive model	1.47	[1.03-2.09]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs16905387-A	Research Support, Non-U.S. Gov't
8	136624184	rs11166605	A	G	rs11166605	23648065	4.23E-05	Recessive model	1.47	[1.02-2.09]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11166605-A	Research Support, Non-U.S. Gov't
8	145677011	rs2721195	T	C	rs2721195	23648065	8.99E-05	Dominant model	1.95	[1.38-2.75]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2721195-G	Research Support, Non-U.S. Gov't
8	145701453	rs750472	A	C	rs750472	23648065	8.99E-05	Dominant model	1.93	[1.37-2.73]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs750472-G	Research Support, Non-U.S. Gov't
9	8737316	rs6477333	A	G	rs6477333	23648065	2.98E-05	Dominant model	2.52	[1.57-4.03]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6477333-A	Research Support, Non-U.S. Gov't
9	10270339	rs2475357	T	G	rs2475357	23648065	6.10E-05	Recessive model	1.33	[1.12-1.58]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2475357-C	Research Support, Non-U.S. Gov't
9	10546257	rs2181158	G	T	rs2181158	23648065	7.13E-05	Allelic model	1.78	[1.34-2.36]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2181158-A	Research Support, Non-U.S. Gov't
9	10561180	rs10756061	T	C	rs10756061	23648065	7.97E-05	Allelic model	1.75	[1.33-2.30]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10756061-G	Research Support, Non-U.S. Gov't
9	10586527	rs13298283	A	C	rs13298283	23648065	2.55E-05	Dominant model	1.89	[1.41-2.54]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs13298283-G	Research Support, Non-U.S. Gov't
9	11101956	rs7044787	G	A	rs7044787	23648065	8.45E-05	Allelic model	1.97	[1.38-2.82]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7044787-C	Research Support, Non-U.S. Gov't
9	11606348	rs10511567	T	C	rs10511567	23648065	1.30E-05	Dominant model	1.72	[1.30-2.29]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10511567-C	Research Support, Non-U.S. Gov't
9	15059821	rs7040444	G	T	rs7040444	23648065	4.77E-05	Recessive model	1.54	[1.11-2.15]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7040444-A	Research Support, Non-U.S. Gov't
9	16349953	rs4961706	G	T	rs4961706	23648065	2.63E-05	Allelic model	2.07	[1.47-2.91]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4961706-G	Research Support, Non-U.S. Gov't
9	18127068	rs10810904	A	G	rs10810904	23648065	6.29E-05	Dominant model	2.25	[1.53-3.32]	150 Japanese ancestry cases; 166 Japanese ancestry controls	Japanese(316)	ALL(316)	ASN(316)	ALL(316)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10810904-C	Research Support, Non-U.S. Gov't
9	19033058	rs10963922	C	A	rs10963922	23648065	8.43E-05	Dominant model	1.24	[1.04-1.48]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10963922-A	Research Support, Non-U.S. Gov't
9	26205694	rs2217796	A	G	rs2217796	23648065	3.65E-05	Allelic model	2.24	[1.55-3.25]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2217796-G	Research Support, Non-U.S. Gov't
9	27546890	rs13691	G	A	rs13691	23648065	6.33E-05	Recessive model	1.8	[1.15-2.81]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs13691-A	Research Support, Non-U.S. Gov't
9	30413575	rs12351836	G	A	rs12351836	23648065	2.66E-05	Allelic model	2.08	[1.48-2.93]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12351836-A	Research Support, Non-U.S. Gov't
9	30467137	rs10813259	A	G	rs10813259	23648065	5.24E-05	Dominant model	1.71	[1.29-2.27]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10813259-T	Research Support, Non-U.S. Gov't
9	30591737	rs1104787	G	A	rs1104787	23648065	6.92E-05	Dominant model	2.22	[1.47-3.34]	150 Japanese ancestry cases; 166 Japanese ancestry controls	Japanese(316)	ALL(316)	ASN(316)	ALL(316)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1104787-G	Research Support, Non-U.S. Gov't
9	31977623	rs1038268	A	G	rs1038268	23648065	4.73E-05	Allelic model	2.33	[1.53-3.54]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1038268-C	Research Support, Non-U.S. Gov't
9	31989998	rs2375811	A	G	rs2375811	23648065	3.17E-05	Allelic model	2.38	[1.57-3.63]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2375811-G	Research Support, Non-U.S. Gov't
9	32007381	rs201642778	T	TG,TT	rs2375814	23648065	8.30E-05	Dominant model	2.32	[1.51-3.56]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2375814-C	Research Support, Non-U.S. Gov't
9	32007381	rs2375814	T	G	rs2375814	23648065	8.30E-05	Dominant model	2.32	[1.51-3.56]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2375814-C	Research Support, Non-U.S. Gov't
9	34978431	rs3739873	G	A	rs3739873	23648065	8.19E-05	Recessive model	1.52	[1.20-1.94]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs3739873-C	Research Support, Non-U.S. Gov't
9	35648950	rs3138083	A	G	rs3138083	23648065	4.00E-06	Allelic model	2.14	[1.55-2.94]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs3138083-A	Research Support, Non-U.S. Gov't
9	38380350	rs4878797	C	A	rs4878797	23648065	8.84E-05	Allelic model	2.1	[1.44-3.06]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4878797-G	Research Support, Non-U.S. Gov't
9	79236165	rs786320	G	A	rs786320	23648065	6.83E-05	Recessive model	1.83	[1.16-2.89]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs786320-C	Research Support, Non-U.S. Gov't
9	80181751	rs7849646	C	T	rs7849646	23648065	7.92E-05	Recessive model	1.39	[1.16-1.66]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7849646-A	Research Support, Non-U.S. Gov't
9	87844016	rs11140900	C	T	rs11140900	23648065	2.95E-05	Recessive model	1.42	[1.05-1.92]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11140900-T	Research Support, Non-U.S. Gov't
9	87845035	rs11140902	C	T	rs11140902	23648065	9.50E-05	Recessive model	1.43	[1.06-1.92]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11140902-A	Research Support, Non-U.S. Gov't
9	88847477	rs942284	C	T	rs942284	23648065	2.42E-05	Dominant model	1.91	[1.24-2.96]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs942284-G	Research Support, Non-U.S. Gov't
9	89191784	rs10780771	A	G	rs10780771	23648065	6.04E-05	Recessive model	1.35	[1.10-1.65]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10780771-A	Research Support, Non-U.S. Gov't
9	94414784	rs2076773	G	A	rs2076773	23648065	6.11E-05	Dominant model	2.26	[1.55-3.29]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2076773-A	Research Support, Non-U.S. Gov't
9	94414784	rs2076773	G	A	rs2076773	23648065	9.85E-05	Dominant model	4.91	[2.18-11.06]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2076773-A	Research Support, Non-U.S. Gov't
9	94420140	rs7032274	T	C	rs7032274	23648065	6.40E-05	Dominant model	1.42	[1.13-1.78]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7032274-C	Research Support, Non-U.S. Gov't
9	94420140	rs7032274	T	C	rs7032274	23648065	7.08E-05	Dominant model	1.29	[1.09-1.53]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7032274-C	Research Support, Non-U.S. Gov't
9	114780290	rs10981210	T	C	rs10981210	23648065	4.87E-05	Dominant model	1.88	[1.28-2.76]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10981210-G	Research Support, Non-U.S. Gov't
9	114981378	rs14255	T	G	rs14255	23648065	3.07E-05	Allelic model	1.54	[1.26-1.88]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs14255-T	Research Support, Non-U.S. Gov't
9	114989616	rs6477900	A	G	rs6477900	23648065	1.46E-05	Allelic model	1.56	[1.28-1.90]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6477900-A	Research Support, Non-U.S. Gov't
9	115039845	rs7875779	T	C	rs7875779	23648065	1.86E-05	Allelic model	1.55	[1.27-1.89]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7875779-T	Research Support, Non-U.S. Gov't
9	115088669	rs4542000	T	C	rs4542000	23648065	1.38E-05	Allelic model	1.56	[1.28-1.90]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4542000-T	Research Support, Non-U.S. Gov't
9	115095743	rs7040447	T	C	rs7040447	23648065	1.37E-05	Allelic model	1.56	[1.28-1.90]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7040447-A	Research Support, Non-U.S. Gov't
9	116125789	rs10981769	T	C	rs10981769	23648065	3.50E-05	Allelic model	4.31	[2.13-8.76]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10981769-A	Research Support, Non-U.S. Gov't
9	118433442	rs10817809	T	C	rs10817809	23648065	2.25E-05	Allelic model	2.1	[1.49-2.96]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10817809-T	Research Support, Non-U.S. Gov't
9	118451241	rs10817817	A	G	rs10817817	23648065	3.18E-05	Allelic model	2.08	[1.48-2.93]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10817817-T	Research Support, Non-U.S. Gov't
9	118475932	rs12380012	C	T	rs12380012	23648065	2.40E-05	Allelic model	2.09	[1.48-2.94]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12380012-G	Research Support, Non-U.S. Gov't
9	120035769	rs6478300	C	A	rs6478300	23648065	1.32E-05	Dominant model	1.54	[1.20-1.96]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6478300-C	Research Support, Non-U.S. Gov't
9	120054021	rs7862566	C	T	rs7862566	23648065	3.15E-05	Recessive model	1.65	[1.25-2.18]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7862566-C	Research Support, Non-U.S. Gov't
9	120054021	rs7862566	C	T	rs7862566	23648065	5.72E-05	Recessive model	1.44	[1.12-1.86]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7862566-C	Research Support, Non-U.S. Gov't
9	121452706	rs10984174	G	A	rs10984174	23648065	6.30E-05	Dominant model	1.38	[1.12-1.70]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10984174-T	Research Support, Non-U.S. Gov't
9	124521260	rs3747851	G	A	rs3747851	23648065	6.00E-07	Allelic model	2.38	[1.69-3.34]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs3747851-T	Research Support, Non-U.S. Gov't
9	126304553	rs10513428	C	T	rs10513428	23648065	8.87E-05	Dominant model	3.13	[1.79-5.47]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10513428-T	Research Support, Non-U.S. Gov't
9	126855342	rs7858299	G	T	rs7858299	23648065	5.69E-05	Allelic model	1.91	[1.38-2.64]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7858299-C	Research Support, Non-U.S. Gov't
9	126860775	rs7860363	C	T	rs7860363	23648065	6.73E-05	Allelic model	1.91	[1.38-2.65]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7860363-G	Research Support, Non-U.S. Gov't
9	126862478	rs7868364	G	T	rs7868364	23648065	7.47E-05	Allelic model	1.88	[1.36-2.61]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7868364-G	Research Support, Non-U.S. Gov't
9	131960870	rs2417135	C	T	rs2417135	23648065	4.08E-05	Allelic model	9.92	[2.31-42.53]	150 Japanese ancestry cases; 166 Japanese ancestry controls	Japanese(316)	ALL(316)	ASN(316)	ALL(316)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2417135-G	Research Support, Non-U.S. Gov't
9	135139826	rs3739927	T	C	rs3739927	23648065	8.25E-05	Dominant model	1.58	[1.24-2.02]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs3739927-C	Research Support, Non-U.S. Gov't
9	136454105	rs28666751	C	T	rs28666751	23648065	8.49E-05	Dominant model	1.78	[1.26-2.51]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs28666751-T	Research Support, Non-U.S. Gov't
9	137098042	rs7872110	T	C	rs7872110	23648065	8.70E-05	Allelic model	2.23	[1.48-3.37]	150 Japanese ancestry cases; 166 Japanese ancestry controls	Japanese(316)	ALL(316)	ASN(316)	ALL(316)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7872110-G	Research Support, Non-U.S. Gov't
9	137120661	rs7848481	T	C	rs7848481	23648065	8.60E-05	Allelic model	2.18	[1.47-3.24]	150 Japanese ancestry cases; 166 Japanese ancestry controls	Japanese(316)	ALL(316)	ASN(316)	ALL(316)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7848481-C	Research Support, Non-U.S. Gov't
9	137125501	rs10785877	G	A	rs10785877	23648065	7.00E-07	Allelic model	2.58	[1.77-3.77]	150 Japanese ancestry cases; 166 Japanese ancestry controls	Japanese(316)	ALL(316)	ASN(316)	ALL(316)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10785877-T	Research Support, Non-U.S. Gov't
9	139535714	rs10735657	G	T	rs10735657	23648065	1.92E-05	Recessive model	1.53	[1.21-1.93]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10735657-C	Research Support, Non-U.S. Gov't
9	139544437	rs7871194	A	C	rs7871194	23648065	3.83E-05	Recessive model	1.41	[1.18-1.69]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7871194-A	Research Support, Non-U.S. Gov't
10	2027751	rs7915592	C	T	rs7915592	23648065	6.38E-05	Dominant model	2.62	[1.44-4.77]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7915592-G	Research Support, Non-U.S. Gov't
10	2291522	rs11817443	T	C	rs11817443	23648065	2.66E-05	Allelic model	4.35	[2.13-8.89]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11817443-G	Research Support, Non-U.S. Gov't
10	2351833	rs768628	T	C	rs768628	23648065	6.52E-05	Dominant model	3.34	[1.82-6.11]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs768628-C	Research Support, Non-U.S. Gov't
10	3949166	rs9651513	G	A	rs9651513	23648065	9.90E-05	Dominant model	1.36	[1.14-1.63]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9651513-G	Research Support, Non-U.S. Gov't
10	4380623	rs4261192	G	T	rs4261192	23648065	5.97E-05	Recessive model	1.55	[1.04-2.32]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4261192-C	Research Support, Non-U.S. Gov't
10	4382152	rs10795158	T	C	rs10795158	23648065	5.97E-05	Recessive model	1.55	[1.04-2.32]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10795158-T	Research Support, Non-U.S. Gov't
10	4384056	rs9633757	C	T	rs9633757	23648065	5.88E-05	Recessive model	1.59	[1.06-2.37]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9633757-A	Research Support, Non-U.S. Gov't
10	4390097	rs11252477	A	G	rs11252477	23648065	5.88E-05	Recessive model	1.79	[1.19-2.70]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11252477-G	Research Support, Non-U.S. Gov't
10	7259446	rs2692840	C	T	rs2692840	23648065	3.98E-05	Dominant model	18.59	[2.44-141.40]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2692840-C	Research Support, Non-U.S. Gov't
10	7265468	rs2692812	T	C	rs2692812	23648065	3.98E-05	Dominant model	18.59	[2.44-141.40]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2692812-A	Research Support, Non-U.S. Gov't
10	7276215	rs10905124	G	A	rs10905124	23648065	3.41E-05	Dominant model	19.02	[2.50-144.80]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10905124-C	Research Support, Non-U.S. Gov't
10	7280550	rs10905129	T	C	rs10905129	23648065	3.98E-05	Dominant model	18.59	[2.44-141.40]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10905129-T	Research Support, Non-U.S. Gov't
10	8545524	rs10795650	A	G	rs10795650	23648065	4.54E-05	Dominant model	1.63	[1.27-2.09]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10795650-C	Research Support, Non-U.S. Gov't
10	11394809	rs3847424	A	G	rs3847424	23648065	6.17E-05	Allelic model	2.21	[1.50-3.27]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs3847424-A	Research Support, Non-U.S. Gov't
10	11396152	rs12245515	G	A	rs12245515	23648065	6.17E-05	Allelic model	2.21	[1.50-3.27]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12245515-G	Research Support, Non-U.S. Gov't
10	11491077	rs1530375	C	T	rs1530375	23648065	1.50E-05	Allelic model	1.8	[1.37-2.36]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1530375-A	Research Support, Non-U.S. Gov't
10	11671268	rs7094839	T	G	rs7094839	23648065	6.75E-05	Allelic model	1.92	[1.38-2.66]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7094839-T	Research Support, Non-U.S. Gov't
10	12959026	rs281849	G	T	rs281849	23648065	3.24E-05	Dominant model	17.95	[2.38-135.60]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs281849-T	Research Support, Non-U.S. Gov't
10	13000495	rs13377047	G	A	rs13377047	23648065	4.10E-05	Recessive model	1.37	[1.07-1.74]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs13377047-A	Research Support, Non-U.S. Gov't
10	25144730	rs10741068	C	T	rs10741068	23648065	9.09E-05	Dominant model	2.11	[1.44-3.08]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10741068-G	Research Support, Non-U.S. Gov't
10	25459750	rs11014431	A	G	rs11014431	23648065	5.19E-05	Recessive model	1.43	[1.20-1.71]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11014431-T	Research Support, Non-U.S. Gov't
10	25459750	rs11014431	A	G	rs11014431	23648065	7.34E-05	Recessive model	1.64	[1.26-2.15]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11014431-T	Research Support, Non-U.S. Gov't
10	25531636	rs915028	A	C	rs915028	23648065	8.64E-05	Allelic model	1.69	[1.30-2.20]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs915028-A	Research Support, Non-U.S. Gov't
10	25532099	rs1339999	C	T	rs1339999	23648065	1.70E-05	Allelic model	1.79	[1.37-2.35]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1339999-C	Research Support, Non-U.S. Gov't
10	25532099	rs1339999	C	T	rs1339999	23648065	7.82E-05	Allelic model	1.43	[1.20-1.72]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1339999-C	Research Support, Non-U.S. Gov't
10	25533536	rs1416995	T	C	rs1416995	23648065	5.31E-05	Allelic model	1.71	[1.31-2.22]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1416995-T	Research Support, Non-U.S. Gov't
10	25576492	rs7902135	G	A	rs7902135	23648065	5.56E-05	Allelic model	1.7	[1.31-2.21]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7902135-G	Research Support, Non-U.S. Gov't
10	28734355	rs7085106	C	T	rs7085106	23648065	5.94E-05	Dominant model	3.15	[1.74-5.69]	150 Japanese ancestry cases; 166 Japanese ancestry controls	Japanese(316)	ALL(316)	ASN(316)	ALL(316)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7085106-T	Research Support, Non-U.S. Gov't
10	29056628	rs787111	C	A	rs787111	23648065	3.26E-05	Dominant model	4.32	[2.10-8.87]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs787111-A	Research Support, Non-U.S. Gov't
10	30099778	rs2986974	A	G	rs2986974	23648065	9.51E-05	Dominant model	1.58	[1.20-2.08]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2986974-G	Research Support, Non-U.S. Gov't
10	30639220	rs11008005	A	G	rs11008005	23648065	7.19E-05	Recessive model	1.62	[1.21-2.17]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11008005-A	Research Support, Non-U.S. Gov't
10	32044641	rs2778646	A	C	rs2778646	23648065	3.73E-05	Allelic model	2.37	[1.56-3.61]	150 Japanese ancestry cases; 166 Japanese ancestry controls	Japanese(316)	ALL(316)	ASN(316)	ALL(316)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2778646-G	Research Support, Non-U.S. Gov't
10	44911999	rs11239035	C	T	rs11239035	23648065	7.13E-05	Dominant model	3.94	[1.93-8.03]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11239035-G	Research Support, Non-U.S. Gov't
10	48471020	rs12414155	T	C	rs12414155	23648065	6.59E-05	Recessive model	1.25	[1.06-1.49]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12414155-G	Research Support, Non-U.S. Gov't
10	49930541	rs17781278	G	A	rs17781278	23648065	6.32E-05	Dominant model	4.62	[1.81-11.74]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs17781278-A	Research Support, Non-U.S. Gov't
10	51570152	rs10740051	G	A	rs10740051	23648065	9.45E-05	Dominant model	1.61	[1.26-2.05]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10740051-A	Research Support, Non-U.S. Gov't
10	54715100	rs10824843	A	G	rs10824843	23648065	2.44E-05	Allelic model	2.1	[1.48-2.97]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10824843-A	Research Support, Non-U.S. Gov't
10	55955444	rs4935502	T	G	rs4935502	23648065	3.62E-05	Dominant model	2.69	[1.64-4.39]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4935502-T	Research Support, Non-U.S. Gov't
10	61113993	rs284609	G	A	rs284609	23648065	8.68E-05	Recessive model	1.26	[0.90-1.78]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs284609-A	Research Support, Non-U.S. Gov't
10	61820631	rs7893313	T	C	rs7893313	23648065	1.01E-05	Recessive model	1.36	[1.15-1.61]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7893313-T	Research Support, Non-U.S. Gov't
10	61902023	rs2288359	T	C	rs2288359	23648065	3.64E-05	Dominant model	1.89	[1.39-2.58]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2288359-T	Research Support, Non-U.S. Gov't
10	64260847	rs12245332	T	C	rs12245332	23648065	2.03E-05	Dominant model	1.9	[1.35-2.67]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12245332-G	Research Support, Non-U.S. Gov't
10	71052508	rs10762277	G	A	rs10762277	23648065	8.23E-05	Dominant model	1.91	[1.31-2.80]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10762277-G	Research Support, Non-U.S. Gov't
10	72331540	rs10762393	A	G	rs10762393	23648065	2.43E-05	Dominant model	4	[1.85-8.64]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10762393-A	Research Support, Non-U.S. Gov't
10	74182400	rs11000295	G	A	rs11000295	23648065	4.38E-05	Allelic model	2.47	[1.62-3.78]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11000295-A	Research Support, Non-U.S. Gov't
10	74183251	rs7069357	G	A	rs7069357	23648065	4.46E-05	Allelic model	2.46	[1.61-3.77]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7069357-A	Research Support, Non-U.S. Gov't
10	74204929	rs1004256	G	A	rs1004256	23648065	4.38E-05	Allelic model	2.47	[1.62-3.78]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1004256-A	Research Support, Non-U.S. Gov't
10	74224647	rs4561121	C	T	rs4561121	23648065	4.38E-05	Allelic model	2.47	[1.62-3.78]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4561121-T	Research Support, Non-U.S. Gov't
10	74482123	rs3009547	T	C	rs3009547	23648065	9.08E-05	Allelic model	2.36	[1.55-3.59]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs3009547-G	Research Support, Non-U.S. Gov't
10	76540987	rs3862556	C	T	rs3862556	23648065	8.47E-05	Allelic model	1.83	[1.36-2.46]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs3862556-A	Research Support, Non-U.S. Gov't
10	76643827	rs11001192	G	A	rs11001192	23648065	8.58E-05	Allelic model	3.02	[1.73-5.26]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11001192-A	Research Support, Non-U.S. Gov't
10	76685101	rs11001204	A	G	rs11001204	23648065	6.41E-05	Allelic model	3.16	[1.80-5.56]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11001204-C	Research Support, Non-U.S. Gov't
10	79525505	rs11002284	C	T	rs11002284	23648065	8.33E-05	Recessive model	1.37	[1.07-1.75]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11002284-T	Research Support, Non-U.S. Gov't
10	83602560	rs2207657	T	C	rs2207657	23648065	8.22E-05	Allelic model	1.42	[1.19-1.69]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2207657-T	Research Support, Non-U.S. Gov't
10	83608508	rs10883825	T	C	rs10883825	23648065	3.43E-05	Allelic model	1.43	[1.21-1.70]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10883825-A	Research Support, Non-U.S. Gov't
10	92688298	rs1539479	A	G	rs1539479	23648065	1.72E-05	Dominant model	2.9	[1.71-4.92]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1539479-T	Research Support, Non-U.S. Gov't
10	92719584	rs7099299	C	T	rs7099299	23648065	8.76E-05	Allelic model	2.73	[1.64-4.54]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7099299-G	Research Support, Non-U.S. Gov't
10	92720630	rs1334583	A	G	rs1334583	23648065	8.75E-05	Allelic model	2.73	[1.64-4.55]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1334583-A	Research Support, Non-U.S. Gov't
10	92770051	rs4933637	A	C	rs4933637	23648065	2.97E-05	Allelic model	2.08	[1.48-2.92]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4933637-C	Research Support, Non-U.S. Gov't
10	92779580	rs4933203	T	C	rs4933203	23648065	6.94E-05	Allelic model	3.46	[1.84-6.50]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4933203-T	Research Support, Non-U.S. Gov't
10	103111057	rs7916830	T	C	rs7916830	23648065	8.13E-05	Recessive model	2.22	[1.44-3.41]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7916830-A	Research Support, Non-U.S. Gov't
10	103124457	rs7090670	A	C	rs7090670	23648065	8.64E-05	Recessive model	2.12	[1.38-3.26]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7090670-A	Research Support, Non-U.S. Gov't
10	103133249	rs10450405	T	C	rs10450405	23648065	8.13E-05	Recessive model	2.14	[1.39-3.29]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10450405-A	Research Support, Non-U.S. Gov't
10	103186838	rs7901883	G	A	rs7901883	23648065	8.13E-05	Recessive model	2.14	[1.39-3.29]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7901883-G	Research Support, Non-U.S. Gov't
10	107460228	rs10509794	T	C	rs10509794	23648065	8.48E-05	Allelic model	16.13	[2.13-122.07]	150 Japanese ancestry cases; 166 Japanese ancestry controls	Japanese(316)	ALL(316)	ASN(316)	ALL(316)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10509794-A	Research Support, Non-U.S. Gov't
10	107523565	rs17119496	T	C	rs17119496	23648065	7.67E-05	Dominant model	1.68	[1.29-2.18]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs17119496-C	Research Support, Non-U.S. Gov't
10	117842360	rs4751949	C	T	rs4751949	23648065	5.27E-05	Allelic model	3.6	[1.95-6.67]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4751949-G	Research Support, Non-U.S. Gov't
10	121186001	rs1889432	A	G	rs1889432	23648065	7.69E-05	Dominant model	1.5	[1.23-1.84]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1889432-G	Research Support, Non-U.S. Gov't
10	121202677	rs11198927	G	A	rs11198927	23648065	9.67E-05	Recessive model	1.36	[0.98-1.87]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11198927-A	Research Support, Non-U.S. Gov't
10	124692586	rs4980169	A	G	rs4980169	23648065	9.56E-05	Allelic model	1.83	[1.33-2.52]	150 Japanese ancestry cases; 166 Japanese ancestry controls	Japanese(316)	ALL(316)	ASN(316)	ALL(316)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4980169-G	Research Support, Non-U.S. Gov't
10	126144839	rs908366	C	T	rs908366	23648065	7.00E-06	Allelic model	2.2	[1.56-3.09]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs908366-A	Research Support, Non-U.S. Gov't
10	126275914	rs12773846	G	A	rs12773846	23648065	1.30E-05	Dominant model	1.68	[1.27-2.22]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12773846-C	Research Support, Non-U.S. Gov't
10	128141955	rs4962558	T	C	rs4962558	23648065	6.04E-05	Allelic model	2.44	[1.54-3.87]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4962558-A	Research Support, Non-U.S. Gov't
10	129713541	rs11018401	G	T	rs11018401	23648065	2.43E-05	Dominant model	2.79	[1.71-4.56]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11018401-T	Research Support, Non-U.S. Gov't
11	710139	rs7942569	G	A	rs7942569	23648065	6.07E-05	Allelic model	2.46	[1.59-3.83]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7942569-A	Research Support, Non-U.S. Gov't
11	1941946	rs909116	T	C	rs909116	23648065	9.63E-05	Allelic model	3.43	[1.86-6.30]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs909116-G	Research Support, Non-U.S. Gov't
11	4406483	rs2269330	A	G	rs2269330	23648065	9.05E-05	Recessive model	1.46	[1.07-1.99]	150 Japanese ancestry cases; 166 Japanese ancestry controls	Japanese(316)	ALL(316)	ASN(316)	ALL(316)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2269330-A	Research Support, Non-U.S. Gov't
11	5904497	rs10500657	T	C	rs10500657	23648065	3.56E-05	Dominant model	1.54	[1.26-1.88]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10500657-T	Research Support, Non-U.S. Gov't
11	5906048	rs4758168	G	A	rs4758168	23648065	3.57E-05	Dominant model	1.54	[1.26-1.88]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4758168-G	Research Support, Non-U.S. Gov't
11	5906073	rs4757986	G	T	rs4757986	23648065	3.58E-05	Dominant model	1.54	[1.26-1.88]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4757986-G	Research Support, Non-U.S. Gov't
11	5906192	rs1453435	A	C	rs1453435	23648065	3.58E-05	Dominant model	1.54	[1.26-1.88]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1453435-T	Research Support, Non-U.S. Gov't
11	7696338	rs12292013	G	T	rs12292013	23648065	7.73E-05	Dominant model	5.88	[2.08-16.63]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12292013-G	Research Support, Non-U.S. Gov't
11	9389875	rs4910048	C	T	rs4910048	23648065	7.33E-05	Dominant model	1.54	[1.19-1.99]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4910048-C	Research Support, Non-U.S. Gov't
11	9825447	rs6483726	C	T	rs6483726	23648065	9.84E-05	Recessive model	1.32	[0.91-1.93]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6483726-G	Research Support, Non-U.S. Gov't
11	13625439	rs1502243	G	A	rs1502243	23648065	5.62E-05	Allelic model	1.8	[1.35-2.40]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1502243-C	Research Support, Non-U.S. Gov't
11	13625439	rs1502243	G	A	rs1502243	23648065	7.18E-05	Allelic model	2.07	[1.42-3.03]	150 Japanese ancestry cases; 166 Japanese ancestry controls	Japanese(316)	ALL(316)	ASN(316)	ALL(316)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1502243-C	Research Support, Non-U.S. Gov't
11	15166201	rs12226609	C	T	rs12226609	23648065	2.74E-05	Allelic model	1.75	[1.34-2.27]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12226609-G	Research Support, Non-U.S. Gov't
11	18822037	rs4627050	A	G	rs4627050	23648065	4.00E-06	Allelic model	1.93	[1.45-2.57]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4627050-G	Research Support, Non-U.S. Gov't
11	18903604	rs7946938	C	T	rs7946938	23648065	9.86E-05	Allelic model	1.84	[1.36-2.51]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7946938-T	Research Support, Non-U.S. Gov't
11	19532506	rs1055543	T	C	rs1055543	23648065	8.47E-05	Recessive model	1.5	[1.06-2.13]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1055543-A	Research Support, Non-U.S. Gov't
11	19668438	rs714585	A	G	rs714585	23648065	5.52E-05	Dominant model	11.31	[2.55-50.15]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs714585-A	Research Support, Non-U.S. Gov't
11	22717120	rs1628924	T	C	rs1628924	23648065	2.25E-05	Dominant model	1.34	[1.11-1.61]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1628924-T	Research Support, Non-U.S. Gov't
11	22729464	rs337454	A	G	rs337454	23648065	2.81E-05	Dominant model	1.35	[1.13-1.63]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs337454-T	Research Support, Non-U.S. Gov't
11	22730694	rs440991	A	G	rs440991	23648065	2.82E-05	Dominant model	1.35	[1.13-1.63]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs440991-T	Research Support, Non-U.S. Gov't
11	23581968	rs11027318	G	A	rs11027318	23648065	7.05E-05	Recessive model	1.49	[1.06-2.10]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11027318-T	Research Support, Non-U.S. Gov't
11	28581430	rs1596300	T	C	rs1596300	23648065	9.37E-05	Dominant model	1.9	[1.33-2.71]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1596300-G	Research Support, Non-U.S. Gov't
11	35074000	rs737503	C	T	rs737503	23648065	5.59E-05	Allelic model	3.55	[1.76-7.13]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs737503-G	Research Support, Non-U.S. Gov't
11	36134670	rs4756281	T	C	rs4756281	23648065	3.07E-05	Allelic model	1.74	[1.35-2.24]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4756281-C	Research Support, Non-U.S. Gov't
11	36202307	rs4755440	G	A	rs4755440	23648065	9.52E-05	Dominant model	3.78	[1.78-8.03]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4755440-A	Research Support, Non-U.S. Gov't
11	36215938	rs12574525	G	T	rs12574525	23648065	4.85E-05	Dominant model	4.54	[1.93-10.69]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12574525-C	Research Support, Non-U.S. Gov't
11	36221890	rs11601619	C	T	rs11601619	23648065	2.81E-05	Dominant model	4.7	[2.00-11.05]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11601619-C	Research Support, Non-U.S. Gov't
11	36233751	rs1374376	G	A	rs1374376	23648065	1.36E-05	Dominant model	4.56	[2.06-10.10]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1374376-G	Research Support, Non-U.S. Gov't
11	36235024	rs12420852	C	T	rs12420852	23648065	4.86E-05	Dominant model	4.62	[1.97-10.87]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12420852-G	Research Support, Non-U.S. Gov't
11	40320791	rs16934689	A	G	rs16934689	23648065	3.58E-05	Dominant model	2.85	[1.73-4.69]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs16934689-C	Research Support, Non-U.S. Gov't
11	40904848	rs11036136	A	G	rs11036136	23648065	7.81E-05	Dominant model	3.65	[1.73-7.71]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11036136-A	Research Support, Non-U.S. Gov't
11	43105620	rs9645617	G	A	rs9645617	23648065	9.84E-05	Dominant model	4.48	[1.88-10.68]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9645617-C	Research Support, Non-U.S. Gov't
11	44784540	rs7104896	G	A	rs7104896	23648065	4.44E-05	Recessive model	1.21	[0.82-1.79]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7104896-C	Research Support, Non-U.S. Gov't
11	69078912	rs10896464	T	C	rs10896464	23648065	5.69E-05	Dominant model	1.72	[1.31-2.27]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10896464-A	Research Support, Non-U.S. Gov't
11	69256899	rs4980627	G	A	rs4980627	23648065	9.03E-05	Recessive model	1.47	[1.15-1.89]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4980627-G	Research Support, Non-U.S. Gov't
11	79941934	rs1628460	G	T	rs1628460	23648065	1.62E-05	Dominant model	1.7	[1.26-2.29]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1628460-G	Research Support, Non-U.S. Gov't
11	80790181	rs1916054	G	A	rs1916054	23648065	9.84E-05	Allelic model	1.44	[1.20-1.73]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1916054-G	Research Support, Non-U.S. Gov't
11	83503404	rs7479949	T	C	rs7479949	23648065	3.40E-05	Dominant model	2.19	[1.42-3.37]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7479949-G	Research Support, Non-U.S. Gov't
11	83512154	rs10898155	C	T	rs10898155	23648065	6.31E-05	Dominant model	2.06	[1.34-3.18]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10898155-T	Research Support, Non-U.S. Gov't
11	84298844	rs7119459	T	C	rs7119459	23648065	9.77E-05	Allelic model	2.49	[1.53-4.04]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7119459-T	Research Support, Non-U.S. Gov't
11	86376739	rs507211	G	A	rs507211	23648065	2.35E-05	Allelic model	2.79	[1.74-4.47]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs507211-G	Research Support, Non-U.S. Gov't
11	86383994	rs682915	T	C	rs682915	23648065	1.57E-05	Allelic model	2.81	[1.75-4.50]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs682915-T	Research Support, Non-U.S. Gov't
11	86386784	rs594361	A	G	rs594361	23648065	1.57E-05	Allelic model	2.81	[1.75-4.50]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs594361-T	Research Support, Non-U.S. Gov't
11	86389000	rs1938936	C	A	rs1938936	23648065	1.98E-05	Allelic model	2.84	[1.77-4.57]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1938936-A	Research Support, Non-U.S. Gov't
11	86389536	rs642245	G	A	rs642245	23648065	2.10E-05	Allelic model	2.81	[1.75-4.52]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs642245-C	Research Support, Non-U.S. Gov't
11	86414027	rs2512988	A	G	rs2512988	23648065	7.58E-06	Allelic model	2.94	[1.83-4.74]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2512988-T	Research Support, Non-U.S. Gov't
11	86414282	rs2512987	A	G	rs2512987	23648065	7.00E-06	Allelic model	2.99	[1.86-4.80]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2512987-T	Research Support, Non-U.S. Gov't
11	87819271	rs2220304	G	A	rs2220304	23648065	3.65E-05	Allelic model	1.69	[1.31-2.19]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2220304-C	Research Support, Non-U.S. Gov't
11	88982718	rs10741305	T	C	rs10741305	23648065	5.32E-05	Allelic model	1.69	[1.31-2.18]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10741305-C	Research Support, Non-U.S. Gov't
11	95854094	rs10765791	C	T	rs10765791	23648065	6.60E-05	Dominant model	1.47	[1.15-1.86]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10765791-G	Research Support, Non-U.S. Gov't
11	98302817	rs10790062	C	T	rs10790062	23648065	6.28E-05	Dominant model	2.73	[1.56-4.77]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10790062-A	Research Support, Non-U.S. Gov't
11	99041999	rs12789966	A	G	rs12789966	23648065	9.74E-05	Dominant model	1.33	[1.12-1.58]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12789966-C	Research Support, Non-U.S. Gov't
11	99044554	rs7114546	C	A	rs7114546	23648065	9.74E-05	Dominant model	1.32	[1.11-1.57]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7114546-C	Research Support, Non-U.S. Gov't
11	110162430	rs1676536	T	C	rs1676536	23648065	7.72E-05	Dominant model	2.06	[1.40-3.03]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1676536-G	Research Support, Non-U.S. Gov't
11	113696653	rs7111825	C	T	rs7111825	23648065	9.01E-05	Recessive model	1.29	[1.08-1.53]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7111825-C	Research Support, Non-U.S. Gov't
11	116559002	rs1145210	C	T	rs1145210	23648065	9.42E-05	Recessive model	1.33	[1.07-1.65]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1145210-A	Research Support, Non-U.S. Gov't
11	117963766	rs11216740	G	A	rs11216740	23648065	6.93E-05	Dominant model	1.86	[1.22-2.86]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11216740-A	Research Support, Non-U.S. Gov't
11	121985367	rs630852	A	G	rs630852	23648065	1.12E-05	Allelic model	2	[1.44-2.79]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs630852-T	Research Support, Non-U.S. Gov't
11	128231995	rs1557477	T	C	rs1557477	23648065	5.34E-05	Recessive model	1.16	[0.95-1.42]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1557477-T	Research Support, Non-U.S. Gov't
11	134503242	rs3019643	A	G	rs3019643	23648065	3.75E-05	Allelic model	1.99	[1.42-2.78]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs3019643-G	Research Support, Non-U.S. Gov't
11	134508438	rs3017963	A	G	rs3017963	23648065	2.83E-05	Allelic model	2	[1.43-2.80]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs3017963-C	Research Support, Non-U.S. Gov't
11	134510309	rs3018015	T	C	rs3018015	23648065	2.83E-05	Allelic model	2	[1.43-2.80]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs3018015-G	Research Support, Non-U.S. Gov't
12	1416592	rs16928347	C	T	rs16928347	23648065	2.42E-05	Dominant model	1.94	[1.37-2.74]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs16928347-A	Research Support, Non-U.S. Gov't
12	3556350	rs6489469	G	A	rs6489469	23648065	5.35E-05	Dominant model	3.01	[1.71-5.30]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6489469-T	Research Support, Non-U.S. Gov't
12	4325316	rs7307707	G	A,C,T	rs7307707	23648065	1.50E-05	Dominant model	1.82	[1.38-2.41]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7307707-T	Research Support, Non-U.S. Gov't
12	5712164	rs4930766	T	C	rs4930766	23648065	7.78E-05	Allelic model	2.9	[1.69-4.97]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4930766-A	Research Support, Non-U.S. Gov't
12	6062853	rs3759320	C	T	rs3759320	23648065	5.26E-05	Dominant model	3.79	[1.75-8.18]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs3759320-A	Research Support, Non-U.S. Gov't
12	6062878	rs3759321	G	A	rs3759321	23648065	9.96E-05	Dominant model	3.65	[1.69-7.91]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs3759321-T	Research Support, Non-U.S. Gov't
12	6442001	rs4149639	T	C	rs4149639	23648065	3.00E-07	Allelic model	4.44	[2.57-7.68]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4149639-C	Research Support, Non-U.S. Gov't
12	6442001	rs4149639	T	C	rs4149639	23648065	7.00E-06	Allelic model	2.76	[1.78-4.29]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4149639-C	Research Support, Non-U.S. Gov't
12	6451561	rs4149621	T	C	rs4149621	23648065	6.59E-06	Allelic model	3.03	[1.91-4.81]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4149621-C	Research Support, Non-U.S. Gov't
12	6451590	rs4149570	A	C	rs4149570	23648065	6.82E-05	Allelic model	1.68	[1.30-2.17]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4149570-G	Research Support, Non-U.S. Gov't
12	14263954	rs17399790	C	T	rs17399790	23648065	4.85E-05	Dominant model	1.94	[1.36-2.77]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs17399790-G	Research Support, Non-U.S. Gov't
12	14266144	rs10845883	T	G	rs10845883	23648065	3.50E-05	Allelic model	4.31	[2.13-8.76]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10845883-C	Research Support, Non-U.S. Gov't
12	14919862	rs10846059	T	C	rs10846059	23648065	6.43E-05	Allelic model	7.15	[2.17-23.57]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10846059-A	Research Support, Non-U.S. Gov't
12	23091991	rs4964061	C	T	rs4964061	23648065	9.29E-05	Recessive model	1.35	[1.08-1.69]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4964061-C	Research Support, Non-U.S. Gov't
12	25834871	rs10771232	A	G	rs10771232	23648065	1.58E-05	Dominant model	1.43	[1.19-1.73]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10771232-A	Research Support, Non-U.S. Gov't
12	31957496	rs4931558	T	C	rs4931558	23648065	6.65E-05	Recessive model	1.36	[1.11-1.66]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4931558-T	Research Support, Non-U.S. Gov't
12	32657276	rs10844223	G	A	rs10844223	23648065	6.61E-05	Allelic model	2.67	[1.62-4.40]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10844223-T	Research Support, Non-U.S. Gov't
12	39130885	rs1352122	G	A	rs1352122	23648065	9.70E-05	Dominant model	2.17	[1.46-3.23]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1352122-G	Research Support, Non-U.S. Gov't
12	45543754	rs9787988	A	G	rs9787988	23648065	6.10E-05	Recessive model	1.36	[1.14-1.63]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9787988-G	Research Support, Non-U.S. Gov't
12	45573620	rs1025090	T	G	rs1025090	23648065	8.93E-05	Recessive model	1.34	[1.13-1.60]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1025090-G	Research Support, Non-U.S. Gov't
12	54319727	rs894734	A	G	rs894734	23648065	4.00E-06	Dominant model	1.62	[1.28-2.05]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs894734-G	Research Support, Non-U.S. Gov't
12	54320805	rs979013	C	A	rs979013	23648065	8.22E-05	Dominant model	1.53	[1.21-1.94]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs979013-A	Research Support, Non-U.S. Gov't
12	54324069	rs2366144	C	A	rs2366144	23648065	6.05E-05	Dominant model	1.55	[1.22-1.97]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2366144-A	Research Support, Non-U.S. Gov't
12	54737701	rs2141587	A	G	rs2141587	23648065	6.50E-05	Dominant model	1.77	[1.33-2.35]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2141587-T	Research Support, Non-U.S. Gov't
12	54737701	rs2141587	A	G	rs2141587	23648065	7.87E-05	Allelic model	1.49	[1.22-1.82]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2141587-T	Research Support, Non-U.S. Gov't
12	54748626	rs4758960	G	A	rs4758960	23648065	1.97E-05	Dominant model	1.48	[1.22-1.80]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4758960-C	Research Support, Non-U.S. Gov't
12	54748626	rs4758960	G	A	rs4758960	23648065	2.28E-05	Dominant model	1.78	[1.35-2.36]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4758960-C	Research Support, Non-U.S. Gov't
12	64209976	rs10506464	C	T	rs10506464	23648065	1.46E-05	Allelic model	2.86	[1.78-4.59]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10506464-G	Research Support, Non-U.S. Gov't
12	64210746	rs12578452	G	A	rs12578452	23648065	2.06E-05	Recessive model	2.45	[1.53-3.92]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12578452-G	Research Support, Non-U.S. Gov't
12	64213103	rs4497499	T	C	rs4497499	23648065	5.02E-05	Recessive model	2.41	[1.51-3.84]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4497499-A	Research Support, Non-U.S. Gov't
12	65280719	rs1144424	C	T	rs1144424	23648065	6.38E-05	Allelic model	2.28	[1.50-3.46]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1144424-G	Research Support, Non-U.S. Gov't
12	68658270	rs4913287	C	T	rs4913287	23648065	1.84E-05	Recessive model	1.5	[1.07-2.10]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4913287-A	Research Support, Non-U.S. Gov't
12	68667462	rs10506557	A	C	rs10506557	23648065	3.34E-05	Recessive model	1.66	[1.18-2.33]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10506557-C	Research Support, Non-U.S. Gov't
12	69567211	rs10878930	G	A	rs10878930	23648065	7.73E-05	Recessive model	1.61	[1.17-2.22]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10878930-A	Research Support, Non-U.S. Gov't
12	70024023	rs710745	T	C	rs710745	23648065	4.80E-05	Recessive model	1.47	[1.15-1.89]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs710745-C	Research Support, Non-U.S. Gov't
12	70067766	rs710722	G	A	rs710722	23648065	7.49E-05	Recessive model	1.51	[1.18-1.93]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs710722-A	Research Support, Non-U.S. Gov't
12	70072916	rs775490	G	T	rs775490	23648065	1.78E-05	Recessive model	1.6	[1.25-2.04]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs775490-T	Research Support, Non-U.S. Gov't
12	70074492	rs775484	A	G	rs775484	23648065	4.99E-05	Recessive model	1.55	[1.21-1.98]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs775484-G	Research Support, Non-U.S. Gov't
12	72903301	rs954147	G	A	rs954147	23648065	2.04E-05	Dominant model	1.43	[1.14-1.80]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs954147-T	Research Support, Non-U.S. Gov't
12	72914831	rs7295506	C	T	rs7295506	23648065	7.68E-05	Dominant model	1.5	[1.19-1.88]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7295506-T	Research Support, Non-U.S. Gov't
12	74429110	rs1829127	G	A	rs1829127	23648065	4.79E-05	Dominant model	1.64	[1.25-2.16]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1829127-C	Research Support, Non-U.S. Gov't
12	75422205	rs10506678	G	T	rs10506678	23648065	6.69E-05	Recessive model	1.35	[1.02-1.78]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10506678-G	Research Support, Non-U.S. Gov't
12	81918056	rs7306960	C	T	rs7306960	23648065	9.19E-05	Dominant model	2.27	[1.47-3.50]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7306960-T	Research Support, Non-U.S. Gov't
12	84465510	rs12426820	T	C	rs12426820	23648065	3.24E-05	Dominant model	2.81	[1.67-4.73]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12426820-A	Research Support, Non-U.S. Gov't
12	84477383	rs10746307	A	C	rs10746307	23648065	4.88E-05	Allelic model	2.77	[1.65-4.67]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10746307-G	Research Support, Non-U.S. Gov't
12	90705400	rs17836993	G	A	rs17836993	23648065	3.81E-05	Dominant model	3.57	[1.74-7.31]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs17836993-G	Research Support, Non-U.S. Gov't
12	95490248	rs12310399	T	C	rs12310399	23648065	2.00E-07	Recessive model	1.85	[1.33-2.58]	150 Japanese ancestry cases; 166 Japanese ancestry controls	Japanese(316)	ALL(316)	ASN(316)	ALL(316)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12310399-A	Research Support, Non-U.S. Gov't
12	95493336	rs4762311	T	C	rs4762311	23648065	2.65E-07	Recessive model	1.96	[1.39-2.76]	150 Japanese ancestry cases; 166 Japanese ancestry controls	Japanese(316)	ALL(316)	ASN(316)	ALL(316)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4762311-A	Research Support, Non-U.S. Gov't
12	95502747	rs6538592	G	A	rs6538592	23648065	5.05E-07	Recessive model	1.94	[1.38-2.74]	150 Japanese ancestry cases; 166 Japanese ancestry controls	Japanese(316)	ALL(316)	ASN(316)	ALL(316)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6538592-A	Research Support, Non-U.S. Gov't
12	103813706	rs10467022	C	T	rs10467022	23648065	3.60E-05	Dominant model	2.46	[1.58-3.81]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10467022-C	Research Support, Non-U.S. Gov't
12	103813706	rs10467022	C	T	rs10467022	23648065	5.40E-05	Dominant model	1.88	[1.34-2.65]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10467022-C	Research Support, Non-U.S. Gov't
12	103817326	rs10745966	C	T	rs10745966	23648065	1.61E-05	Dominant model	1.8	[1.35-2.41]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10745966-G	Research Support, Non-U.S. Gov't
12	103849908	rs2374076	A	C	rs2374076	23648065	3.63E-05	Dominant model	1.78	[1.33-2.38]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2374076-T	Research Support, Non-U.S. Gov't
12	103864665	rs4506750	A	G	rs4506750	23648065	1.49E-05	Dominant model	1.86	[1.39-2.48]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4506750-T	Research Support, Non-U.S. Gov't
12	103866354	rs2888731	T	G	rs2888731	23648065	1.61E-05	Dominant model	1.84	[1.38-2.46]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2888731-A	Research Support, Non-U.S. Gov't
12	110227965	rs10735104	C	T	rs10735104	23648065	2.06E-05	Allelic model	4.44	[2.22-8.90]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10735104-A	Research Support, Non-U.S. Gov't
12	122630909	rs1043763	G	A	rs1043763	23648065	7.00E-06	Dominant model	1.5	[1.25-1.79]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1043763-T	Research Support, Non-U.S. Gov't
12	124894184	rs12582168	T	C	rs12582168	23648065	9.00E-06	Dominant model	1.45	[1.21-1.75]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12582168-C	Research Support, Non-U.S. Gov't
12	126944404	rs4765391	T	C	rs4765391	23648065	7.17E-05	Dominant model	4.91	[2.18-11.06]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4765391-A	Research Support, Non-U.S. Gov't
12	127846842	rs1684227	T	G	rs1684227	23648065	6.22E-05	Recessive model	1.28	[1.08-1.52]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1684227-G	Research Support, Non-U.S. Gov't
12	128762741	rs12302898	G	A	rs12302898	23648065	4.75E-05	Allelic model	5.55	[2.09-14.74]	150 Japanese ancestry cases; 166 Japanese ancestry controls	Japanese(316)	ALL(316)	ASN(316)	ALL(316)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12302898-A	Research Support, Non-U.S. Gov't
12	128916550	rs10773542	G	T	rs10773542	23648065	5.62E-05	Allelic model	2.14	[1.48-3.08]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10773542-A	Research Support, Non-U.S. Gov't
12	130770170	rs7960284	C	T	rs7960284	23648065	4.58E-05	Recessive model	1.99	[1.23-3.21]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7960284-C	Research Support, Non-U.S. Gov't
12	130893588	rs7304899	A	G	rs7304899	23648065	8.85E-05	Dominant model	1.8	[1.31-2.46]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7304899-A	Research Support, Non-U.S. Gov't
13	21043086	rs4573790	G	A	rs4573790	23648065	6.76E-05	Dominant model	5.86	[2.23-15.43]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4573790-T	Research Support, Non-U.S. Gov't
13	21047858	rs9506494	C	T	rs9506494	23648065	7.17E-05	Dominant model	1.3	[1.08-1.56]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9506494-A	Research Support, Non-U.S. Gov't
13	21048924	rs9552195	G	A	rs9552195	23648065	4.41E-05	Dominant model	1.31	[1.09-1.58]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9552195-T	Research Support, Non-U.S. Gov't
13	21050575	rs7989332	A	C	rs7989332	23648065	5.00E-06	Allelic model	2.06	[1.51-2.81]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7989332-G	Research Support, Non-U.S. Gov't
13	21057250	rs9552196	C	T	rs9552196	23648065	6.12E-05	Dominant model	1.3	[1.07-1.57]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9552196-C	Research Support, Non-U.S. Gov't
13	22753687	rs9510015	T	C	rs9510015	23648065	9.29E-06	Dominant model	1.33	[1.12-1.58]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9510015-C	Research Support, Non-U.S. Gov't
13	22754093	rs9580312	A	G	rs9580312	23648065	8.00E-06	Dominant model	1.33	[1.12-1.58]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9580312-G	Research Support, Non-U.S. Gov't
13	22762222	rs9510029	A	G	rs9510029	23648065	6.47E-05	Dominant model	1.34	[1.13-1.59]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9510029-G	Research Support, Non-U.S. Gov't
13	22770518	rs10781825	A	C	rs10781825	23648065	2.33E-05	Dominant model	1.33	[1.12-1.58]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10781825-G	Research Support, Non-U.S. Gov't
13	24525604	rs2147995	A	C	rs2147995	23648065	3.63E-05	Recessive model	1.25	[1.03-1.53]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2147995-C	Research Support, Non-U.S. Gov't
13	24525604	rs35747503	A	AG	rs2147995	23648065	3.63E-05	Recessive model	1.25	[1.03-1.53]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2147995-C	Research Support, Non-U.S. Gov't
13	24878466	rs3803218	A	G	rs3803218	23648065	2.11E-05	Allelic model	2.25	[1.54-3.29]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs3803218-C	Research Support, Non-U.S. Gov't
13	25331027	rs3803217	A	C	rs3803217	23648065	8.52E-05	Dominant model	2.61	[1.53-4.46]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs3803217-C	Research Support, Non-U.S. Gov't
13	28360487	rs1923834	C	T	rs1923834	23648065	5.00E-06	Dominant model	3.24	[1.82-5.74]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1923834-G	Research Support, Non-U.S. Gov't
13	33561520	rs527337	G	A	rs527337	23648065	3.20E-05	Recessive model	1.52	[1.19-1.94]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs527337-A	Research Support, Non-U.S. Gov't
13	39786449	rs9532354	G	A	rs9532354	23648065	9.93E-05	Dominant model	1.77	[1.25-2.49]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9532354-C	Research Support, Non-U.S. Gov't
13	46288145	rs7317245	A	G	rs7317245	23648065	7.89E-05	Allelic model	1.59	NA	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7317245-T	Research Support, Non-U.S. Gov't
13	46290082	rs9316155	T	C	rs9316155	23648065	1.51E-05	Allelic model	1.66	[1.32-2.08]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9316155-A	Research Support, Non-U.S. Gov't
13	46291526	rs9534199	T	C	rs9534199	23648065	1.69E-05	Allelic model	1.67	[1.33-2.10]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9534199-A	Research Support, Non-U.S. Gov't
13	46750002	rs2209090	A	G	rs2209090	23648065	2.67E-05	Recessive model	1.76	[1.19-2.58]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2209090-G	Research Support, Non-U.S. Gov't
13	51701547	rs1340544	T	C	rs1340544	23648065	1.78E-05	Allelic model	2.14	[1.52-3.02]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1340544-C	Research Support, Non-U.S. Gov't
13	51709017	rs9563028	C	A	rs9563028	23648065	1.66E-05	Recessive model	1.99	[1.41-2.79]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9563028-A	Research Support, Non-U.S. Gov't
13	51709017	rs9563028	C	A	rs9563028	23648065	8.13E-05	Recessive model	2.14	[1.39-3.29]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9563028-A	Research Support, Non-U.S. Gov't
13	59477851	rs9597893	T	C	rs9597893	23648065	7.87E-05	Recessive model	2.12	[1.15-3.91]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9597893-T	Research Support, Non-U.S. Gov't
13	60250843	rs1350361	G	A	rs1350361	23648065	5.14E-05	Dominant model	2.4	[1.52-3.77]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1350361-G	Research Support, Non-U.S. Gov't
13	60273298	rs7336489	C	T	rs7336489	23648065	4.82E-05	Dominant model	2.42	[1.53-3.83]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7336489-G	Research Support, Non-U.S. Gov't
13	60818288	rs9570280	C	A	rs9570280	23648065	5.58E-05	Allelic model	2.22	[1.50-3.28]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9570280-C	Research Support, Non-U.S. Gov't
13	61729112	rs7994213	T	C	rs7994213	23648065	4.47E-05	Recessive model	1.37	[1.04-1.80]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7994213-G	Research Support, Non-U.S. Gov't
13	61738208	rs993877	C	T	rs993877	23648065	3.54E-05	Recessive model	1.3	[0.99-1.69]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs993877-A	Research Support, Non-U.S. Gov't
13	61867517	rs9539095	C	T	rs9539095	23648065	1.82E-05	Recessive model	1.53	[1.13-2.06]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9539095-A	Research Support, Non-U.S. Gov't
13	67267982	rs7322694	A	G	rs7322694	23648065	7.49E-05	Dominant model	2.46	[1.48-4.09]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7322694-A	Research Support, Non-U.S. Gov't
13	67379709	rs956277	C	T	rs956277	23648065	4.46E-05	Dominant model	1.79	[1.33-2.40]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs956277-C	Research Support, Non-U.S. Gov't
13	71983341	rs1999603	A	G	rs1999603	23648065	1.47E-05	Recessive model	1.37	[1.00-1.86]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1999603-G	Research Support, Non-U.S. Gov't
13	71999805	rs8000025	A	C	rs8000025	23648065	2.38E-05	Recessive model	1.37	[1.01-1.87]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs8000025-G	Research Support, Non-U.S. Gov't
13	72031460	rs9529897	C	T	rs9529897	23648065	1.49E-05	Recessive model	1.47	[1.07-2.01]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9529897-T	Research Support, Non-U.S. Gov't
13	77540631	rs592425	C	T	rs592425	23648065	6.93E-05	Allelic model	2.11	[1.47-3.02]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs592425-C	Research Support, Non-U.S. Gov't
13	93088651	rs4771859	T	C	rs4771859	23648065	1.00E-06	Recessive model	1.33	[1.09-1.62]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4771859-G	Research Support, Non-U.S. Gov't
13	94861913	rs7984149	T	C	rs7984149	23648065	7.39E-05	Allelic model	2.14	[1.48-3.10]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7984149-C	Research Support, Non-U.S. Gov't
13	95853870	rs1751027	A	G	rs1751027	23648065	9.40E-05	Allelic model	1.63	[1.29-2.06]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1751027-C	Research Support, Non-U.S. Gov't
13	96128857	rs7984974	G	A	rs7984974	23648065	3.74E-05	Dominant model	1.64	[1.28-2.10]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7984974-C	Research Support, Non-U.S. Gov't
13	96129510	rs946232	A	G	rs946232	23648065	3.74E-05	Dominant model	1.64	[1.28-2.10]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs946232-T	Research Support, Non-U.S. Gov't
13	96852913	rs4771929	G	A	rs4771929	23648065	9.95E-05	Dominant model	2	[1.32-3.02]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4771929-C	Research Support, Non-U.S. Gov't
13	96965955	rs7331682	T	C	rs7331682	23648065	6.88E-05	Dominant model	1.83	[1.30-2.56]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7331682-G	Research Support, Non-U.S. Gov't
13	106596719	rs488248	C	T	rs488248	23648065	3.00E-06	Allelic model	2.9	[1.80-4.67]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs488248-T	Research Support, Non-U.S. Gov't
13	106614005	rs7317081	G	T	rs7317081	23648065	9.21E-06	Allelic model	2.82	[1.74-4.58]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7317081-A	Research Support, Non-U.S. Gov't
13	106862224	rs7338679	G	A	rs7338679	23648065	2.54E-05	Allelic model	1.85	[1.38-2.48]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7338679-C	Research Support, Non-U.S. Gov't
13	108129963	rs1323679	T	C	rs1323679	23648065	9.84E-05	Allelic model	2.07	[1.45-2.96]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1323679-G	Research Support, Non-U.S. Gov't
13	108151476	rs1555637	C	A	rs1555637	23648065	7.18E-05	Allelic model	2.04	[1.44-2.90]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1555637-A	Research Support, Non-U.S. Gov't
13	110653926	rs9559702	T	C	rs9559702	23648065	7.79E-05	Allelic model	2.14	[1.47-3.11]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9559702-G	Research Support, Non-U.S. Gov't
13	111049623	rs9515203	T	C	rs9515203	23648065	1.78E-05	Dominant model	1.95	[1.43-2.67]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9515203-C	Research Support, Non-U.S. Gov't
13	112865110	rs928195	T	C	rs928195	23648065	5.49E-05	Recessive model	1.59	[1.24-2.03]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs928195-G	Research Support, Non-U.S. Gov't
13	112870029	rs7321489	A	G	rs7321489	23648065	9.89E-05	Dominant model	1.57	[1.22-2.02]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7321489-G	Research Support, Non-U.S. Gov't
14	21770681	rs17792599	A	G	rs17792599	23648065	8.45E-05	Dominant model	19.45	[2.47-153.09]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs17792599-T	Research Support, Non-U.S. Gov't
14	22886319	rs3811236	C	A,G,T	rs3811236	23648065	9.63E-05	Allelic model	2	[1.41-2.85]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs3811236-A	Research Support, Non-U.S. Gov't
14	22915816	rs12147516	G	T	rs12147516	23648065	7.05E-05	Recessive model	1.4	[1.19-1.66]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12147516-A	Research Support, Non-U.S. Gov't
14	22937656	rs12589282	A	C	rs12589282	23648065	4.00E-06	Recessive model	1.48	[1.25-1.75]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12589282-G	Research Support, Non-U.S. Gov't
14	23311480	rs17243048	G	A	rs17243048	23648065	7.27E-05	Recessive model	1.63	[1.16-2.28]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs17243048-A	Research Support, Non-U.S. Gov't
14	26654291	rs4349058	C	T	rs4349058	23648065	5.23E-05	Recessive model	1.29	[1.06-1.56]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4349058-T	Research Support, Non-U.S. Gov't
14	29198059	rs968045	G	A	rs968045	23648065	9.63E-05	Recessive model	1.66	[1.19-2.32]	150 Japanese ancestry cases; 166 Japanese ancestry controls	Japanese(316)	ALL(316)	ASN(316)	ALL(316)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs968045-T	Research Support, Non-U.S. Gov't
14	29243242	rs17114266	G	T	rs17114266	23648065	3.50E-05	Recessive model	1.28	[1.07-1.52]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs17114266-A	Research Support, Non-U.S. Gov't
14	30003238	rs1191545	G	T	rs1191545	23648065	9.47E-05	Dominant model	1.78	[1.32-2.41]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1191545-A	Research Support, Non-U.S. Gov't
14	33011647	rs1998242	G	A	rs1998242	23648065	7.09E-05	Allelic model	1.69	[1.31-2.19]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1998242-A	Research Support, Non-U.S. Gov't
14	36402546	rs1168978	T	C	rs1168978	23648065	8.11E-05	Dominant model	1.3	[1.10-1.55]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1168978-C	Research Support, Non-U.S. Gov't
14	41194262	rs11157160	G	A	rs11157160	23648065	3.29E-05	Recessive model	1.84	[1.27-2.67]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11157160-G	Research Support, Non-U.S. Gov't
14	42547320	rs4451874	A	G	rs4451874	23648065	8.20E-05	Recessive model	1.41	[1.10-1.81]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4451874-G	Research Support, Non-U.S. Gov't
14	44623260	rs10147827	A	G	rs10147827	23648065	7.37E-05	Allelic model	14.26	[3.08-66.11]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10147827-C	Research Support, Non-U.S. Gov't
14	56231800	rs7494275	A	C	rs7494275	23648065	9.00E-06	Recessive model	1.73	[1.23-2.43]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7494275-C	Research Support, Non-U.S. Gov't
14	56238629	rs10150228	T	G	rs10150228	23648065	5.40E-05	Allelic model	2.44	[1.58-3.78]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10150228-C	Research Support, Non-U.S. Gov't
14	67949074	rs17249111	A	G	rs17249111	23648065	9.26E-05	Dominant model	2.54	[1.57-4.13]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs17249111-G	Research Support, Non-U.S. Gov't
14	69984560	rs2756966	G	A	rs2756966	23648065	6.24E-05	Recessive model	1.37	[0.97-1.94]	150 Japanese ancestry cases; 166 Japanese ancestry controls	Japanese(316)	ALL(316)	ASN(316)	ALL(316)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2756966-G	Research Support, Non-U.S. Gov't
14	71649124	rs11623881	C	T	rs11623881	23648065	1.17E-05	Recessive model	1.47	[1.07-2.00]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11623881-C	Research Support, Non-U.S. Gov't
14	75795136	rs12895755	C	T	rs12895755	23648065	7.43E-05	Recessive model	1.49	[1.22-1.83]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12895755-A	Research Support, Non-U.S. Gov't
14	84438074	rs1015277	A	C	rs1015277	23648065	3.63E-05	Dominant model	2.1	[1.46-3.01]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1015277-C	Research Support, Non-U.S. Gov't
14	84463633	rs7140245	T	G	rs7140245	23648065	2.57E-05	Dominant model	2.13	[1.51-3.02]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7140245-C	Research Support, Non-U.S. Gov't
14	84485390	rs17119456	A	G	rs17119456	23648065	7.57E-05	Dominant model	1.96	[1.41-2.75]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs17119456-C	Research Support, Non-U.S. Gov't
14	84509670	rs17119553	A	G	rs17119553	23648065	4.02E-05	Dominant model	1.79	[1.36-2.36]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs17119553-G	Research Support, Non-U.S. Gov't
14	86850928	rs804930	C	T	rs804930	23648065	1.09E-05	Dominant model	1.5	[1.24-1.82]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs804930-C	Research Support, Non-U.S. Gov't
14	86898200	rs10484102	G	A	rs10484102	23648065	1.11E-05	Allelic model	1.62	[1.30-2.02]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10484102-G	Research Support, Non-U.S. Gov't
14	86902054	rs12882718	C	T	rs12882718	23648065	6.00E-06	Dominant model	1.56	[1.28-1.88]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12882718-T	Research Support, Non-U.S. Gov't
14	86923368	rs10132264	T	C	rs10132264	23648065	4.28E-05	Allelic model	1.56	[1.26-1.94]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10132264-A	Research Support, Non-U.S. Gov't
14	87672957	rs1484981	C	A	rs1484981	23648065	9.67E-05	Recessive model	1.17	[0.81-1.69]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1484981-T	Research Support, Non-U.S. Gov't
14	87740087	rs17123224	C	T	rs17123224	23648065	4.32E-05	Recessive model	1.26	[0.87-1.83]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs17123224-A	Research Support, Non-U.S. Gov't
14	87741025	rs1756650	C	T	rs1756650	23648065	2.00E-06	Recessive model	1.39	[0.95-2.01]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1756650-G	Research Support, Non-U.S. Gov't
14	87752261	rs7142552	A	G	rs7142552	23648065	3.18E-05	Recessive model	1.44	[1.07-1.94]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7142552-C	Research Support, Non-U.S. Gov't
14	87770671	rs1365524	T	G	rs1365524	23648065	6.54E-05	Recessive model	1.61	[1.20-2.15]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1365524-C	Research Support, Non-U.S. Gov't
14	87795892	rs1430561	G	A	rs1430561	23648065	8.02E-05	Recessive model	1.6	[1.19-2.14]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1430561-A	Research Support, Non-U.S. Gov't
14	88355122	rs10133218	G	T	rs10133218	23648065	6.16E-05	Dominant model	1.38	[1.16-1.65]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10133218-T	Research Support, Non-U.S. Gov't
14	90031107	rs243183	G	A	rs243183	23648065	3.41E-05	Allelic model	1.68	[1.32-2.15]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs243183-T	Research Support, Non-U.S. Gov't
14	92534915	rs8004149	C	T	rs8004149	23648065	9.63E-05	Recessive model	1.31	[1.10-1.57]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs8004149-G	Research Support, Non-U.S. Gov't
14	92548785	rs1048755	C	T	rs1048755	23648065	7.45E-05	Recessive model	1.31	[1.10-1.56]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1048755-C	Research Support, Non-U.S. Gov't
14	92559862	rs1997919	C	T	rs1997919	23648065	7.38E-05	Recessive model	1.31	[1.10-1.56]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1997919-C	Research Support, Non-U.S. Gov't
14	94422192	rs12882974	C	T	rs12882974	23648065	4.88E-05	Allelic model	1.7	[1.32-2.19]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12882974-T	Research Support, Non-U.S. Gov't
14	94422346	rs730959	A	G	rs730959	23648065	7.93E-05	Allelic model	1.7	[1.31-2.21]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs730959-T	Research Support, Non-U.S. Gov't
14	97983221	rs1001504	C	A	rs1001504	23648065	3.99E-05	Recessive model	1.27	[1.04-1.53]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1001504-G	Research Support, Non-U.S. Gov't
14	97987857	rs8022296	G	A	rs8022296	23648065	7.00E-06	Recessive model	1.27	[1.06-1.52]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs8022296-G	Research Support, Non-U.S. Gov't
14	98000813	rs17095542	G	A	rs17095542	23648065	3.75E-05	Recessive model	1.25	[1.03-1.50]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs17095542-C	Research Support, Non-U.S. Gov't
14	99782579	rs8018158	C	T	rs8018158	23648065	8.33E-05	Recessive model	1.57	[1.11-2.21]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs8018158-G	Research Support, Non-U.S. Gov't
15	26990651	rs8038471	G	A	rs8038471	23648065	7.57E-05	Allelic model	1.99	[1.42-2.79]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs8038471-G	Research Support, Non-U.S. Gov't
15	31463378	rs7169523	G	A	rs7169523	23648065	7.99E-05	Recessive model	1.39	[0.97-1.98]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7169523-A	Research Support, Non-U.S. Gov't
15	35537031	rs318339	G	T	rs318339	23648065	6.97E-05	Allelic model	1.75	[1.32-2.33]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs318339-G	Research Support, Non-U.S. Gov't
15	35548468	rs2622756	A	G	rs2622756	23648065	6.86E-05	Allelic model	1.76	[1.33-2.34]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2622756-A	Research Support, Non-U.S. Gov't
15	38739298	rs12905733	T	G	rs12905733	23648065	7.40E-05	Dominant model	1.57	[1.21-2.04]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12905733-G	Research Support, Non-U.S. Gov't
15	38779626	rs12591633	A	G	rs12591633	23648065	7.05E-05	Dominant model	1.59	[1.22-2.08]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12591633-G	Research Support, Non-U.S. Gov't
15	38783682	rs7181389	G	A	rs7181389	23648065	7.40E-05	Dominant model	1.61	[1.23-2.09]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7181389-T	Research Support, Non-U.S. Gov't
15	38791826	rs4334257	A	C	rs4334257	23648065	7.70E-05	Dominant model	1.59	[1.22-2.08]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4334257-G	Research Support, Non-U.S. Gov't
15	40728036	rs12368	C	T	rs12368	23648065	5.82E-05	Recessive model	1.42	[1.02-1.97]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12368-T	Research Support, Non-U.S. Gov't
15	41249871	rs3887640	T	G	rs3887640	23648065	3.69E-05	Dominant model	2.29	[1.50-3.47]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs3887640-T	Research Support, Non-U.S. Gov't
15	46640863	rs1564781	T	C	rs1564781	23648065	5.18E-05	Allelic model	2.25	[1.52-3.31]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1564781-T	Research Support, Non-U.S. Gov't
15	51471700	rs12441919	A	C	rs12441919	23648065	9.97E-05	Allelic model	1.62	[1.27-2.06]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12441919-C	Research Support, Non-U.S. Gov't
15	53702840	rs12911817	T	G	rs12911817	23648065	4.41E-05	Dominant model	1.52	[1.18-1.95]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12911817-G	Research Support, Non-U.S. Gov't
15	53709744	rs4776147	T	C	rs4776147	23648065	4.20E-05	Dominant model	1.52	[1.19-1.95]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4776147-C	Research Support, Non-U.S. Gov't
15	53758922	rs671948	A	C	rs671948	23648065	4.37E-05	Allelic model	1.69	[1.31-2.18]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs671948-G	Research Support, Non-U.S. Gov't
15	55946732	rs9920546	C	T	rs9920546	23648065	5.06E-06	Dominant model	3.69	[2.01-6.78]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9920546-T	Research Support, Non-U.S. Gov't
15	55950082	rs11071200	C	A	rs11071200	23648065	9.00E-07	Dominant model	8.24	[2.89-23.52]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11071200-T	Research Support, Non-U.S. Gov't
15	56000063	rs2414424	C	T	rs2414424	23648065	4.30E-05	Allelic model	1.8	[1.36-2.39]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2414424-A	Research Support, Non-U.S. Gov't
15	58733512	rs166362	G	A	rs166362	23648065	7.74E-05	Recessive model	1.62	[1.26-2.09]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs166362-G	Research Support, Non-U.S. Gov't
15	60001060	rs11071474	T	C	rs11071474	23648065	4.29E-05	Recessive model	1.47	[1.03-2.10]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11071474-T	Research Support, Non-U.S. Gov't
15	61223718	rs1482050	A	C	rs1482050	23648065	9.76E-05	Allelic model	1.59	[1.26-2.00]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1482050-T	Research Support, Non-U.S. Gov't
15	62764680	rs370873	C	T	rs370873	23648065	4.25E-05	Recessive model	2.42	[1.52-3.87]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs370873-C	Research Support, Non-U.S. Gov't
15	63161831	rs625901	A	G	rs625901	23648065	6.53E-05	Allelic model	2.9	[1.72-4.89]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs625901-G	Research Support, Non-U.S. Gov't
15	63566702	rs1017546	A	C	rs1017546	23648065	2.48E-05	Recessive model	1.57	[1.19-2.07]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1017546-G	Research Support, Non-U.S. Gov't
15	63569017	rs3784672	G	T	rs3784672	23648065	8.39E-05	Recessive model	1.52	[1.08-2.15]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs3784672-T	Research Support, Non-U.S. Gov't
15	63569184	rs3784671	C	A	rs3784671	23648065	1.47E-05	Recessive model	1.59	[1.21-2.10]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs3784671-A	Research Support, Non-U.S. Gov't
15	67241653	rs266300	T	C	rs266300	23648065	6.25E-05	Allelic model	1.67	[1.30-2.15]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs266300-T	Research Support, Non-U.S. Gov't
15	71449398	rs5024066	A	G	rs5024066	23648065	7.43E-05	Allelic model	1.64	[1.29-2.09]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs5024066-T	Research Support, Non-U.S. Gov't
15	71904835	rs11858418	A	G	rs11858418	23648065	2.43E-05	Recessive model	1.41	[1.05-1.89]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11858418-T	Research Support, Non-U.S. Gov't
15	71904835	rs11858418	A	G	rs11858418	23648065	6.47E-05	Recessive model	1.16	[0.97-1.38]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11858418-T	Research Support, Non-U.S. Gov't
15	71905049	rs13329645	G	A	rs13329645	23648065	2.43E-05	Recessive model	1.41	[1.05-1.89]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs13329645-C	Research Support, Non-U.S. Gov't
15	71905049	rs13329645	G	A	rs13329645	23648065	6.47E-05	Recessive model	1.16	[0.97-1.38]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs13329645-C	Research Support, Non-U.S. Gov't
15	74770334	rs8027459	G	A	rs8027459	23648065	9.26E-05	Allelic model	3.38	[1.87-6.12]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs8027459-A	Research Support, Non-U.S. Gov't
15	75128501	rs9210	T	C	rs9210	23648065	1.18E-05	Dominant model	1.7	[1.30-2.22]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9210-G	Research Support, Non-U.S. Gov't
15	75131661	rs4886615	A	G	rs4886615	23648065	1.76E-05	Dominant model	1.68	[1.29-2.20]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4886615-G	Research Support, Non-U.S. Gov't
15	75132319	rs936229	A	G	rs936229	23648065	4.00E-06	Dominant model	1.69	[1.30-2.18]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs936229-G	Research Support, Non-U.S. Gov't
15	75140854	rs3765066	G	A	rs3765066	23648065	4.98E-05	Recessive model	1.28	[1.08-1.52]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs3765066-T	Research Support, Non-U.S. Gov't
15	75140854	rs3765066	G	A	rs3765066	23648065	8.90E-05	Recessive model	1.32	[1.03-1.69]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs3765066-T	Research Support, Non-U.S. Gov't
15	75159433	rs11072511	A	G	rs11072511	23648065	8.80E-05	Recessive model	1.41	[0.98-2.03]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11072511-C	Research Support, Non-U.S. Gov't
15	75189930	rs1130741	A	G	rs1130741	23648065	8.66E-05	Recessive model	1.4	[0.97-2.02]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1130741-G	Research Support, Non-U.S. Gov't
15	75196176	rs4886636	G	A	rs4886636	23648065	8.66E-05	Recessive model	1.4	[0.97-2.02]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4886636-T	Research Support, Non-U.S. Gov't
15	75255322	rs6495132	C	T	rs6495132	23648065	6.28E-05	Allelic model	1.42	[1.19-1.68]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6495132-C	Research Support, Non-U.S. Gov't
15	75344451	rs4886651	C	T	rs4886651	23648065	5.66E-05	Allelic model	3.31	[1.86-5.90]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4886651-G	Research Support, Non-U.S. Gov't
15	75385622	rs7162941	C	T	rs7162941	23648065	2.08E-05	Allelic model	1.45	[1.22-1.71]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7162941-G	Research Support, Non-U.S. Gov't
15	75449674	rs4886670	G	T	rs4886670	23648065	1.00E-06	Allelic model	1.61	[1.33-1.94]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4886670-A	Research Support, Non-U.S. Gov't
15	75449674	rs4886670	G	T	rs4886670	23648065	7.00E-06	Allelic model	1.84	[1.41-2.38]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4886670-A	Research Support, Non-U.S. Gov't
15	75472094	rs16966785	A	G	rs16966785	23648065	8.78E-05	Dominant model	1.37	[1.14-1.64]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs16966785-A	Research Support, Non-U.S. Gov't
15	78164706	rs11857176	T	C	rs11857176	23648065	8.00E-07	Recessive model	1.8	[1.13-2.87]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11857176-A	Research Support, Non-U.S. Gov't
15	83387752	rs7182320	G	A	rs7182320	23648065	9.24E-05	Recessive model	1.94	[1.17-3.25]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7182320-A	Research Support, Non-U.S. Gov't
15	85405369	rs306198	A	G	rs306198	23648065	6.83E-05	Recessive model	2.06	[1.26-3.35]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs306198-C	Research Support, Non-U.S. Gov't
15	85415386	rs12900463	T	C	rs12900463	23648065	4.00E-06	Recessive model	2.15	[1.34-3.46]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12900463-C	Research Support, Non-U.S. Gov't
15	85415799	rs4842994	C	T	rs4842994	23648065	4.03E-06	Recessive model	2.15	[1.34-3.46]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4842994-A	Research Support, Non-U.S. Gov't
15	86068022	rs12910789	C	T	rs12910789	23648065	7.46E-05	Recessive model	1.47	[1.10-1.95]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12910789-G	Research Support, Non-U.S. Gov't
15	88756201	rs4887212	T	C	rs4887212	23648065	8.17E-05	Dominant model	1.52	[1.09-2.13]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4887212-T	Research Support, Non-U.S. Gov't
15	89238255	rs6496520	A	C	rs6496520	23648065	4.72E-05	Recessive model	1.29	[1.08-1.54]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6496520-T	Research Support, Non-U.S. Gov't
15	94179432	rs4777936	T	C	rs4777936	23648065	8.80E-05	Dominant model	1.53	[1.10-2.11]	150 Japanese ancestry cases; 166 Japanese ancestry controls	Japanese(316)	ALL(316)	ASN(316)	ALL(316)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4777936-C	Research Support, Non-U.S. Gov't
15	94371122	rs7172139	C	T	rs7172139	23648065	8.38E-05	Recessive model	1.35	[1.12-1.64]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7172139-C	Research Support, Non-U.S. Gov't
15	94669167	rs7174567	G	A	rs7174567	23648065	2.75E-05	Recessive model	2.44	[1.29-4.59]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7174567-T	Research Support, Non-U.S. Gov't
15	96809782	rs1437588	A	G	rs1437588	23648065	4.77E-05	Dominant model	1.94	[1.39-2.70]	150 Japanese ancestry cases; 166 Japanese ancestry controls	Japanese(316)	ALL(316)	ASN(316)	ALL(316)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1437588-T	Research Support, Non-U.S. Gov't
15	96809782	rs1437588	A	G	rs1437588	23648065	7.82E-05	Dominant model	1.51	[1.19-1.92]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1437588-T	Research Support, Non-U.S. Gov't
15	101972931	rs8024621	G	A	rs8024621	23648065	1.22E-05	Dominant model	1.8	[1.35-2.40]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs8024621-T	Research Support, Non-U.S. Gov't
16	3550147	rs11077346	C	A	rs11077346	23648065	8.75E-05	Dominant model	1.39	[1.09-1.77]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11077346-C	Research Support, Non-U.S. Gov't
16	5409673	rs1358489	C	T	rs1358489	23648065	1.46E-05	Allelic model	2.14	[1.51-3.03]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1358489-A	Research Support, Non-U.S. Gov't
16	8044973	rs9933906	C	T	rs9933906	23648065	7.83E-05	Recessive model	1.81	[1.12-2.92]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9933906-G	Research Support, Non-U.S. Gov't
16	13043431	rs7189560	T	C	rs7189560	23648065	4.89E-05	Dominant model	2.28	[1.46-3.54]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7189560-C	Research Support, Non-U.S. Gov't
16	13046720	rs924546	A	G	rs924546	23648065	7.91E-05	Dominant model	2.23	[1.44-3.45]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs924546-C	Research Support, Non-U.S. Gov't
16	13467705	rs2051738	T	C	rs2051738	23648065	6.76E-05	Dominant model	2.42	[1.33-4.39]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2051738-C	Research Support, Non-U.S. Gov't
16	17271327	rs752482	T	C	rs752482	23648065	3.39E-05	Allelic model	1.8	[1.37-2.36]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs752482-G	Research Support, Non-U.S. Gov't
16	22885421	rs2238486	G	A	rs2238486	23648065	1.09E-05	Dominant model	1.63	[1.25-2.12]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2238486-T	Research Support, Non-U.S. Gov't
16	22889186	rs2519974	G	A	rs2519974	23648065	4.00E-06	Dominant model	1.65	[1.26-2.15]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2519974-T	Research Support, Non-U.S. Gov't
16	22891084	rs916670	C	T	rs916670	23648065	9.96E-05	Recessive model	1.48	[1.15-1.91]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs916670-G	Research Support, Non-U.S. Gov't
16	25011619	rs8061484	C	T	rs8061484	23648065	8.92E-05	Allelic model	1.63	[1.28-2.08]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs8061484-G	Research Support, Non-U.S. Gov't
16	30500761	rs3087438	G	A	rs3087438	23648065	2.77E-05	Recessive model	1.3	[1.08-1.55]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs3087438-G	Research Support, Non-U.S. Gov't
16	46644903	rs35313904	G	A	rs35313904	23648065	3.40E-05	Dominant model	1.97	[1.28-3.03]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs35313904-G	Research Support, Non-U.S. Gov't
16	48602733	rs12443883	C	T	rs12443883	23648065	3.90E-05	Dominant model	1.61	[1.24-2.08]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12443883-A	Research Support, Non-U.S. Gov't
16	51658435	rs2647967	C	T	rs2647967	23648065	8.44E-05	Recessive model	1.24	[1.01-1.51]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2647967-G	Research Support, Non-U.S. Gov't
16	51666146	rs2647969	T	G	rs2647969	23648065	9.36E-05	Recessive model	1.22	[1.00-1.48]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2647969-A	Research Support, Non-U.S. Gov't
16	51666246	rs2647970	A	G	rs2647970	23648065	9.44E-05	Recessive model	1.22	[1.00-1.49]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2647970-A	Research Support, Non-U.S. Gov't
16	54514123	rs12929998	A	C	rs12929998	23648065	2.77E-05	Dominant model	2.1	[1.44-3.06]	150 Japanese ancestry cases; 166 Japanese ancestry controls	Japanese(316)	ALL(316)	ASN(316)	ALL(316)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12929998-C	Research Support, Non-U.S. Gov't
16	54527296	rs12051408	T	C	rs12051408	23648065	8.16E-05	Dominant model	1.41	[1.13-1.74]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12051408-T	Research Support, Non-U.S. Gov't
16	54733746	rs1420562	T	C	rs1420562	23648065	8.27E-05	Recessive model	1.33	[1.12-1.58]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1420562-T	Research Support, Non-U.S. Gov't
16	54851741	rs4410070	A	C	rs4410070	23648065	7.11E-05	Dominant model	1.35	[1.13-1.60]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4410070-C	Research Support, Non-U.S. Gov't
16	56812300	rs13329802	C	T	rs13329802	23648065	6.34E-05	Allelic model	1.6	[1.27-2.01]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs13329802-A	Research Support, Non-U.S. Gov't
16	60577200	rs1530795	T	C	rs1530795	23648065	6.37E-05	Recessive model	1.35	[1.06-1.72]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1530795-T	Research Support, Non-U.S. Gov't
16	62131626	rs9938191	T	C	rs9938191	23648065	1.40E-05	Allelic model	2.33	[1.61-3.37]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9938191-C	Research Support, Non-U.S. Gov't
16	62137472	rs9924310	G	A	rs9924310	23648065	5.16E-05	Allelic model	2.22	[1.53-3.23]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9924310-T	Research Support, Non-U.S. Gov't
16	74861095	rs6564173	A	G	rs6564173	23648065	5.41E-05	Recessive model	1.6	[1.25-2.05]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6564173-C	Research Support, Non-U.S. Gov't
16	77310808	rs7201773	A	G	rs7201773	23648065	7.87E-05	Recessive model	2.31	[1.22-4.36]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7201773-C	Research Support, Non-U.S. Gov't
16	77319899	rs12934894	A	G	rs12934894	23648065	8.33E-05	Recessive model	1.46	[1.19-1.79]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12934894-G	Research Support, Non-U.S. Gov't
16	77322254	rs17712956	A	G	rs17712956	23648065	3.14E-05	Recessive model	1.45	[1.18-1.79]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs17712956-C	Research Support, Non-U.S. Gov't
16	77328895	rs12935229	C	T	rs12935229	23648065	4.00E-06	Recessive model	1.5	[1.21-1.84]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12935229-A	Research Support, Non-U.S. Gov't
16	77328990	rs12935394	C	A	rs12935394	23648065	4.40E-06	Recessive model	1.5	[1.21-1.84]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12935394-T	Research Support, Non-U.S. Gov't
16	78872859	rs11649397	G	A	rs11649397	23648065	4.02E-05	Dominant model	2.11	[1.46-3.05]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11649397-A	Research Support, Non-U.S. Gov't
16	79063156	rs2550698	T	G	rs2550698	23648065	4.10E-05	Allelic model	3.46	[1.80-6.66]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2550698-A	Research Support, Non-U.S. Gov't
16	79067690	rs2656641	C	T	rs2656641	23648065	3.02E-05	Allelic model	3.68	[1.86-7.27]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2656641-G	Research Support, Non-U.S. Gov't
16	80032104	rs11645885	C	A	rs11645885	23648065	6.33E-05	Recessive model	1.85	[1.18-2.89]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11645885-G	Research Support, Non-U.S. Gov't
16	80050661	rs11642717	A	G	rs11642717	23648065	5.63E-05	Allelic model	2.47	[1.59-3.84]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11642717-T	Research Support, Non-U.S. Gov't
16	80568573	rs4577099	C	T	rs4577099	23648065	3.50E-05	Allelic model	1.94	[1.42-2.65]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4577099-A	Research Support, Non-U.S. Gov't
16	81774798	rs12446319	T	C	rs12446319	23648065	9.00E-06	Allelic model	2.03	[1.48-2.77]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12446319-A	Research Support, Non-U.S. Gov't
16	81984437	rs4888197	A	G	rs4888197	23648065	1.32E-05	Allelic model	2.45	[1.66-3.62]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4888197-G	Research Support, Non-U.S. Gov't
16	83412113	rs1013465	T	G	rs1013465	23648065	6.50E-05	Dominant model	1.46	[1.18-1.80]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1013465-C	Research Support, Non-U.S. Gov't
16	83417673	rs12050931	A	C	rs12050931	23648065	2.76E-05	Recessive model	1.34	[1.13-1.60]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12050931-C	Research Support, Non-U.S. Gov't
16	83626088	rs16960938	G	A	rs16960938	23648065	3.60E-05	Recessive model	1.61	[1.19-2.17]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs16960938-T	Research Support, Non-U.S. Gov't
16	83662293	rs16961072	C	T	rs16961072	23648065	6.94E-05	Allelic model	1.84	[1.37-2.49]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs16961072-G	Research Support, Non-U.S. Gov't
16	84654935	rs2925055	A	G	rs2925055	23648065	1.69E-05	Allelic model	1.45	[1.23-1.72]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2925055-C	Research Support, Non-U.S. Gov't
16	86093721	rs4843897	A	G	rs4843897	23648065	1.99E-05	Dominant model	1.41	[1.19-1.67]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4843897-T	Research Support, Non-U.S. Gov't
16	89703424	rs445537	A	G	rs445537	23648065	9.77E-05	Allelic model	2.56	[1.61-4.08]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs445537-C	Research Support, Non-U.S. Gov't
17	1866892	rs4525525	G	T	rs4525525	23648065	4.64E-05	Allelic model	1.69	[1.32-2.16]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4525525-T	Research Support, Non-U.S. Gov't
17	2589022	rs7216704	C	T	rs7216704	23648065	9.29E-05	Dominant model	1.94	NA	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7216704-T	Research Support, Non-U.S. Gov't
17	3313127	rs11656466	C	T	rs11656466	23648065	3.63E-05	Dominant model	1.57	[1.21-2.02]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11656466-C	Research Support, Non-U.S. Gov't
17	3342002	rs9303174	A	C	rs9303174	23648065	7.50E-05	Dominant model	1.57	[1.20-2.05]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9303174-T	Research Support, Non-U.S. Gov't
17	4955206	rs8072032	G	T	rs8072032	23648065	8.31E-05	Dominant model	3.51	[1.82-6.76]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs8072032-G	Research Support, Non-U.S. Gov't
17	4989326	rs4790741	A	G	rs4790741	23648065	3.34E-05	Allelic model	4.58	[2.24-9.35]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4790741-G	Research Support, Non-U.S. Gov't
17	5770670	rs7218232	C	T	rs7218232	23648065	5.03E-05	Recessive model	1.69	[1.22-2.35]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7218232-G	Research Support, Non-U.S. Gov't
17	9808571	rs2286531	T	G	rs2286531	23648065	9.67E-05	Recessive model	1.51	[1.16-1.97]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2286531-A	Research Support, Non-U.S. Gov't
17	9874145	rs3826529	G	A	rs3826529	23648065	8.01E-06	Recessive model	1.55	[1.22-1.97]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs3826529-A	Research Support, Non-U.S. Gov't
17	9875205	rs3786094	T	C	rs3786094	23648065	6.00E-06	Recessive model	1.53	[1.21-1.94]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs3786094-C	Research Support, Non-U.S. Gov't
17	10681423	rs8080671	A	G	rs8080671	23648065	7.90E-05	Recessive model	1.45	NA	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs8080671-G	Research Support, Non-U.S. Gov't
17	12777402	rs11651483	A	G	rs11651483	23648065	3.00E-07	Recessive model	1.36	[1.12-1.64]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11651483-C	Research Support, Non-U.S. Gov't
17	16315919	rs7217735	A	G	rs7217735	23648065	3.05E-05	Allelic model	2.08	[1.47-2.93]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7217735-T	Research Support, Non-U.S. Gov't
17	16318932	rs3813769	T	C	rs3813769	23648065	3.53E-05	Allelic model	2.09	[1.47-2.96]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs3813769-T	Research Support, Non-U.S. Gov't
17	30206059	rs11658318	T	C	rs11658318	23648065	1.94E-05	Recessive model	2.25	[1.52-3.32]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11658318-T	Research Support, Non-U.S. Gov't
17	30809455	rs4523973	G	A	rs4523973	23648065	5.32E-05	Allelic model	2.61	[1.58-4.30]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4523973-C	Research Support, Non-U.S. Gov't
17	30812845	rs756785	T	C	rs756785	23648065	5.41E-05	Allelic model	2.63	[1.60-4.34]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs756785-T	Research Support, Non-U.S. Gov't
17	30820176	rs2285428	T	C	rs2285428	23648065	5.41E-05	Allelic model	2.63	[1.60-4.34]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2285428-T	Research Support, Non-U.S. Gov't
17	31938138	rs12943567	T	C	rs12943567	23648065	5.62E-05	Dominant model	3.51	[1.82-6.78]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12943567-T	Research Support, Non-U.S. Gov't
17	36034423	rs3110647	A	G	rs3110647	23648065	6.44E-05	Allelic model	1.65	[1.29-2.11]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs3110647-G	Research Support, Non-U.S. Gov't
17	39444101	rs12451126	C	T	rs12451126	23648065	8.95E-05	Dominant model	1.38	[1.15-1.66]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12451126-T	Research Support, Non-U.S. Gov't
17	39453510	rs12449502	C	T	rs12449502	23648065	9.05E-05	Dominant model	1.38	[1.15-1.65]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12449502-A	Research Support, Non-U.S. Gov't
17	43733264	rs1706719	C	T	rs1706719	23648065	8.57E-05	Allelic model	1.98	[1.43-2.75]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1706719-G	Research Support, Non-U.S. Gov't
17	44868187	rs12452064	G	A	rs12452064	23648065	9.10E-05	Allelic model	2	[1.42-2.82]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12452064-C	Research Support, Non-U.S. Gov't
17	45406167	rs11867160	A	G	rs11867160	23648065	9.25E-05	Allelic model	3.5	[1.86-6.56]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11867160-A	Research Support, Non-U.S. Gov't
17	45490251	rs3883318	C	T	rs3883318	23648065	9.25E-05	Allelic model	3.5	[1.86-6.56]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs3883318-G	Research Support, Non-U.S. Gov't
17	48718531	rs4148409	T	C,G	rs4148409	23648065	4.27E-05	Allelic model	2.57	[1.61-4.11]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4148409-C	Research Support, Non-U.S. Gov't
17	49853021	rs2319453	T	C	rs2319453	23648065	4.18E-05	Recessive model	1.46	[1.14-1.87]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2319453-A	Research Support, Non-U.S. Gov't
17	54262845	rs9911043	G	A	rs9911043	23648065	7.90E-05	Allelic model	4	[1.99-8.03]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9911043-C	Research Support, Non-U.S. Gov't
17	54813751	rs227665	A	C	rs227665	23648065	3.24E-05	Recessive model	1.48	[1.17-1.87]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs227665-G	Research Support, Non-U.S. Gov't
17	58907917	rs9899338	T	G	rs9899338	23648065	4.68E-05	Dominant model	2.38	[1.51-3.73]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9899338-T	Research Support, Non-U.S. Gov't
17	58921974	rs4456565	T	C	rs4456565	23648065	4.92E-05	Dominant model	2.35	[1.50-3.69]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4456565-T	Research Support, Non-U.S. Gov't
17	58998658	rs6504006	C	T	rs6504006	23648065	5.14E-05	Dominant model	2.34	[1.49-3.67]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6504006-C	Research Support, Non-U.S. Gov't
17	59003189	rs7213603	T	C	rs7213603	23648065	9.79E-05	Dominant model	2.19	[1.45-3.29]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7213603-T	Research Support, Non-U.S. Gov't
17	59017025	rs8080784	T	C	rs8080784	23648065	9.79E-05	Dominant model	2.19	[1.45-3.29]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs8080784-A	Research Support, Non-U.S. Gov't
17	59022395	rs9914370	A	G	rs9914370	23648065	9.79E-05	Dominant model	2.19	[1.45-3.29]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9914370-A	Research Support, Non-U.S. Gov't
17	59087808	rs9652858	G	A	rs9652858	23648065	6.44E-05	Dominant model	2.21	[1.47-3.33]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9652858-G	Research Support, Non-U.S. Gov't
17	61616959	rs4968656	A	G	rs4968656	23648065	4.07E-05	Recessive model	1.31	[1.10-1.57]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4968656-G	Research Support, Non-U.S. Gov't
17	61619379	rs12949197	C	T	rs12949197	23648065	4.07E-05	Recessive model	1.32	[1.10-1.58]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12949197-T	Research Support, Non-U.S. Gov't
17	62259376	rs9896542	A	G	rs9896542	23648065	8.09E-05	Dominant model	2.26	[1.44-3.56]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9896542-A	Research Support, Non-U.S. Gov't
17	62266253	rs4968701	C	T	rs4968701	23648065	2.03E-05	Dominant model	2.47	[1.57-3.88]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4968701-C	Research Support, Non-U.S. Gov't
17	62268147	rs1010940	A	G	rs1010940	23648065	4.93E-05	Dominant model	2.34	[1.49-3.67]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1010940-T	Research Support, Non-U.S. Gov't
17	62268535	rs11079531	G	A	rs11079531	23648065	4.93E-05	Dominant model	2.34	[1.49-3.67]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11079531-G	Research Support, Non-U.S. Gov't
17	62317999	rs9915054	A	G	rs9915054	23648065	4.93E-05	Dominant model	2.34	[1.49-3.67]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9915054-T	Research Support, Non-U.S. Gov't
17	67215712	rs12941264	C	T	rs12941264	23648065	2.69E-05	Recessive model	1.41	[1.16-1.72]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12941264-C	Research Support, Non-U.S. Gov't
17	68666455	rs2367005	T	G	rs2367005	23648065	9.80E-05	Dominant model	1.61	[1.25-2.07]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2367005-A	Research Support, Non-U.S. Gov't
17	69980044	rs2190492	G	T	rs2190492	23648065	1.70E-05	Dominant model	4.09	[1.87-8.96]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2190492-T	Research Support, Non-U.S. Gov't
17	69986412	rs10512580	C	A	rs10512580	23648065	2.71E-05	Dominant model	4.05	[1.85-8.87]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10512580-A	Research Support, Non-U.S. Gov't
17	70091433	rs9903394	A	G	rs9903394	23648065	4.99E-05	Dominant model	1.38	[1.16-1.65]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9903394-T	Research Support, Non-U.S. Gov't
17	70721707	rs8071840	A	G	rs8071840	23648065	8.72E-05	Allelic model	3.45	[1.88-6.35]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs8071840-G	Research Support, Non-U.S. Gov't
17	70735225	rs9944510	G	T	rs9944510	23648065	8.72E-05	Allelic model	3.45	[1.88-6.35]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9944510-A	Research Support, Non-U.S. Gov't
17	71600245	rs790092	T	C	rs790092	23648065	8.40E-05	Allelic model	5.07	[2.12-12.15]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs790092-C	Research Support, Non-U.S. Gov't
17	72422081	rs16978038	T	C	rs16978038	23648065	8.90E-05	Allelic model	2.2	[1.49-3.25]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs16978038-C	Research Support, Non-U.S. Gov't
17	72751663	rs9904111	C	T	rs9904111	23648065	5.23E-05	Allelic model	2.35	[1.52-3.65]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9904111-C	Research Support, Non-U.S. Gov't
17	72769739	rs2305213	A	G	rs2305213	23648065	6.83E-05	Allelic model	2.8	[1.63-4.80]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2305213-T	Research Support, Non-U.S. Gov't
17	72769739	rs2305213	A	G	rs2305213	23648065	8.93E-05	Allelic model	2.11	[1.42-3.13]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2305213-T	Research Support, Non-U.S. Gov't
17	75608685	rs1077759	C	T	rs1077759	23648065	4.23E-05	Dominant model	2.1	[1.39-3.18]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1077759-G	Research Support, Non-U.S. Gov't
17	76613675	rs4796808	G	T	rs4796808	23648065	9.24E-05	Recessive model	1.85	[1.27-2.70]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4796808-G	Research Support, Non-U.S. Gov't
17	77268173	rs4274472	G	A	rs4274472	23648065	6.94E-05	Recessive model	1.62	[1.19-2.22]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4274472-G	Research Support, Non-U.S. Gov't
17	77909438	rs3169601	T	C	rs3169601	23648065	7.04E-05	Recessive model	1.42	[0.99-2.02]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs3169601-A	Research Support, Non-U.S. Gov't
18	954465	rs1610274	G	A	rs1610274	23648065	2.45E-05	Recessive model	1.55	[1.21-1.98]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1610274-C	Research Support, Non-U.S. Gov't
18	958056	rs8090931	G	A	rs8090931	23648065	1.09E-05	Recessive model	1.58	[1.24-2.03]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs8090931-C	Research Support, Non-U.S. Gov't
18	3670649	rs1675244	A	G	rs1675244	23648065	8.96E-05	Recessive model	1.7	[1.11-2.60]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1675244-T	Research Support, Non-U.S. Gov't
18	3671652	rs1116345	T	C	rs1116345	23648065	9.68E-05	Recessive model	1.68	[1.10-2.56]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1116345-A	Research Support, Non-U.S. Gov't
18	4074007	rs7240625	T	G	rs7240625	23648065	6.22E-05	Dominant model	2.65	[1.59-4.44]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7240625-C	Research Support, Non-U.S. Gov't
18	4539085	rs7228133	G	T	rs7228133	23648065	2.00E-06	Recessive model	1.26	[1.03-1.52]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7228133-C	Research Support, Non-U.S. Gov't
18	8711942	rs1249489	G	A	rs1249489	23648065	3.67E-05	Recessive model	2.07	[1.41-3.04]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1249489-C	Research Support, Non-U.S. Gov't
18	11259831	rs1566198	G	T	rs1566198	23648065	5.80E-05	Recessive model	1.42	[1.11-1.82]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1566198-G	Research Support, Non-U.S. Gov't
18	25507049	rs12709794	C	T	rs12709794	23648065	3.02E-05	Dominant model	2.33	[1.38-3.92]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12709794-C	Research Support, Non-U.S. Gov't
18	28110019	rs972697	G	A	rs972697	23648065	9.00E-05	Allelic model	1.81	[1.35-2.43]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs972697-C	Research Support, Non-U.S. Gov't
18	29407057	rs639595	G	A	rs639595	23648065	8.20E-05	Recessive model	1.27	[1.06-1.51]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs639595-C	Research Support, Non-U.S. Gov't
18	29424289	rs9966530	A	G	rs9966530	23648065	6.04E-05	Recessive model	1.27	[1.07-1.52]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9966530-T	Research Support, Non-U.S. Gov't
18	29561668	rs4799615	C	A	rs4799615	23648065	9.79E-05	Recessive model	1.38	[1.15-1.64]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4799615-A	Research Support, Non-U.S. Gov't
18	36884204	rs2032268	T	C	rs2032268	23648065	8.83E-05	Allelic model	1.83	[1.36-2.48]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2032268-C	Research Support, Non-U.S. Gov't
18	36886378	rs10502722	T	G	rs10502722	23648065	6.73E-05	Allelic model	1.84	[1.36-2.49]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10502722-C	Research Support, Non-U.S. Gov't
18	46283912	rs1542593	G	A	rs1542593	23648065	6.77E-05	Allelic model	2.18	[1.51-3.15]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1542593-A	Research Support, Non-U.S. Gov't
18	48243318	rs7240429	T	C	rs7240429	23648065	1.69E-05	Allelic model	2.32	[1.57-3.43]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7240429-T	Research Support, Non-U.S. Gov't
18	50903050	rs17504372	C	T	rs17504372	23648065	5.99E-05	Allelic model	3.02	[1.82-5.03]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs17504372-A	Research Support, Non-U.S. Gov't
18	53693949	rs1364417	C	A	rs1364417	23648065	5.91E-05	Recessive model	2.39	[1.29-4.43]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1364417-T	Research Support, Non-U.S. Gov't
18	56165164	rs2277720	G	A	rs2277720	23648065	4.41E-05	Allelic model	1.69	[1.31-2.19]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2277720-C	Research Support, Non-U.S. Gov't
18	58208260	rs12455135	C	T	rs12455135	23648065	5.17E-05	Dominant model	1.33	[1.12-1.57]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12455135-T	Research Support, Non-U.S. Gov't
18	58869249	rs1008632	C	T	rs1008632	23648065	8.30E-05	Recessive model	1.53	[1.18-1.98]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1008632-G	Research Support, Non-U.S. Gov't
18	62164462	rs9960678	T	C	rs9960678	23648065	2.17E-05	Recessive model	1.48	[1.05-2.08]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9960678-A	Research Support, Non-U.S. Gov't
18	62170726	rs4553720	T	C	rs4553720	23648065	7.00E-06	Recessive model	1.55	[1.13-2.12]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4553720-T	Research Support, Non-U.S. Gov't
18	67363227	rs4312402	T	C	rs4312402	23648065	1.73E-05	Recessive model	1.5	[1.10-2.05]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4312402-G	Research Support, Non-U.S. Gov't
18	74484734	rs4890871	G	A	rs4890871	23648065	6.14E-06	Dominant model	1.67	[1.30-2.14]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4890871-T	Research Support, Non-U.S. Gov't
18	74488280	rs2406342	G	T	rs2406342	23648065	2.00E-06	Dominant model	1.7	[1.32-2.18]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2406342-T	Research Support, Non-U.S. Gov't
18	75605399	rs9961113	T	C	rs9961113	23648065	1.00E-06	Allelic model	2.47	[1.71-3.58]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9961113-C	Research Support, Non-U.S. Gov't
19	5421962	rs11667049	A	G	rs11667049	23648065	9.16E-05	Dominant model	1.35	[1.14-1.60]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11667049-A	Research Support, Non-U.S. Gov't
19	5423643	rs1384936	C	T	rs1384936	23648065	1.56E-05	Allelic model	1.49	[1.25-1.78]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1384936-C	Research Support, Non-U.S. Gov't
19	5425795	rs4807760	T	C	rs4807760	23648065	4.48E-05	Allelic model	1.51	[1.24-1.84]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4807760-T	Research Support, Non-U.S. Gov't
19	6042059	rs2288846	C	T	rs2288846	23648065	9.76E-05	Allelic model	1.94	[1.38-2.72]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2288846-C	Research Support, Non-U.S. Gov't
19	6095431	rs17304450	G	A	rs17304450	23648065	8.34E-05	Allelic model	1.66	[1.28-2.15]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs17304450-C	Research Support, Non-U.S. Gov't
19	6475613	rs3745571	T	C	rs3745571	23648065	8.00E-06	Dominant model	1.73	[1.28-2.34]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs3745571-T	Research Support, Non-U.S. Gov't
19	7487313	rs4804602	G	A	rs4804602	23648065	5.12E-05	Dominant model	1.46	[1.14-1.86]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4804602-G	Research Support, Non-U.S. Gov't
19	7488671	rs11260076	A	G	rs11260076	23648065	8.67E-05	Dominant model	1.47	[1.15-1.87]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11260076-T	Research Support, Non-U.S. Gov't
19	10596780	rs9676881	G	A	rs9676881	23648065	9.12E-05	Recessive model	1.41	[1.05-1.89]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9676881-T	Research Support, Non-U.S. Gov't
19	14574252	rs4926214	A	G	rs4926214	23648065	8.55E-05	Allelic model	1.71	[1.30-2.24]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4926214-A	Research Support, Non-U.S. Gov't
19	15133787	rs10424547	C	A	rs10424547	23648065	2.64E-05	Dominant model	1.54	[1.21-1.97]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10424547-C	Research Support, Non-U.S. Gov't
19	15133926	rs8112667	C	A	rs8112667	23648065	3.60E-05	Dominant model	1.54	[1.21-1.96]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs8112667-C	Research Support, Non-U.S. Gov't
19	15133926	rs8112667	C	A	rs8112667	23648065	9.33E-05	Dominant model	1.73	[1.25-2.39]	150 Japanese ancestry cases; 166 Japanese ancestry controls	Japanese(316)	ALL(316)	ASN(316)	ALL(316)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs8112667-C	Research Support, Non-U.S. Gov't
19	17546710	rs7254837	T	C	rs7254837	23648065	3.93E-05	Allelic model	2.02	[1.41-2.89]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7254837-G	Research Support, Non-U.S. Gov't
19	20054823	rs6511061	G	A	rs6511061	23648065	7.51E-05	Recessive model	1.17	[0.97-1.41]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6511061-T	Research Support, Non-U.S. Gov't
19	20108062	rs8104863	T	C	rs8104863	23648065	5.27E-05	Allelic model	3.4	[1.84-6.30]	83 Japanese ancestry cases; 66 Japanese ancestry controls	Japanese(149)	ALL(149)	ASN(149)	ALL(149)	Adverse response to chemotherapy (neutropenia/leucopenia) (doxorubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs8104863-G	Research Support, Non-U.S. Gov't
19	20238148	rs1725939	A	C	rs1725939	23648065	2.00E-05	Allelic model	1.71	[1.33-2.18]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1725939-G	Research Support, Non-U.S. Gov't
19	20242274	rs1618723	G	A	rs1618723	23648065	1.52E-05	Allelic model	1.72	[1.34-2.20]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1618723-T	Research Support, Non-U.S. Gov't
19	20291263	rs836896	T	C	rs836896	23648065	1.40E-05	Recessive model	1.72	[1.35-2.21]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs836896-G	Research Support, Non-U.S. Gov't
19	20329111	rs1654260	G	A	rs1654260	23648065	8.00E-06	Allelic model	1.75	[1.37-2.24]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1654260-A	Research Support, Non-U.S. Gov't
19	20329637	rs1654261	G	A	rs1654261	23648065	8.49E-06	Allelic model	1.75	[1.37-2.24]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1654261-T	Research Support, Non-U.S. Gov't
19	20411543	rs7247148	A	G	rs7247148	23648065	8.87E-05	Allelic model	1.61	[1.27-2.04]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7247148-C	Research Support, Non-U.S. Gov't
19	20466055	rs7254670	T	C	rs7254670	23648065	5.99E-05	Recessive model	1.51	[1.20-1.90]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7254670-C	Research Support, Non-U.S. Gov't
19	22438069	rs283147	A	C	rs283147	23648065	4.25E-05	Recessive model	1.57	[1.11-2.21]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs283147-T	Research Support, Non-U.S. Gov't
19	23468966	rs431270	A	C	rs431270	23648065	3.17E-05	Allelic model	2.86	[1.76-4.64]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs431270-A	Research Support, Non-U.S. Gov't
19	23545250	rs1044095	A	G	rs1044095	23648065	3.17E-05	Allelic model	2.86	[1.76-4.64]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1044095-G	Research Support, Non-U.S. Gov't
19	23685823	rs2640203	T	C	rs2640203	23648065	7.01E-05	Allelic model	2.81	[1.71-4.60]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2640203-T	Research Support, Non-U.S. Gov't
19	28597809	rs2867823	C	A	rs2867823	23648065	9.94E-05	Dominant model	1.98	[1.36-2.89]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2867823-T	Research Support, Non-U.S. Gov't
19	28835571	rs2159327	G	A	rs2159327	23648065	2.66E-06	Dominant model	1.87	[1.35-2.60]	150 Japanese ancestry cases; 166 Japanese ancestry controls	Japanese(316)	ALL(316)	ASN(316)	ALL(316)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2159327-C	Research Support, Non-U.S. Gov't
19	28866596	rs995834	G	A	rs995834	23648065	1.00E-06	Dominant model	1.87	[1.36-2.57]	150 Japanese ancestry cases; 166 Japanese ancestry controls	Japanese(316)	ALL(316)	ASN(316)	ALL(316)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs995834-C	Research Support, Non-U.S. Gov't
19	29757697	rs2193516	G	A	rs2193516	23648065	3.29E-05	Allelic model	1.87	[1.39-2.50]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2193516-C	Research Support, Non-U.S. Gov't
19	29761748	rs888301	T	C	rs888301	23648065	6.06E-05	Allelic model	1.84	[1.38-2.47]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs888301-A	Research Support, Non-U.S. Gov't
19	29764587	rs12460869	T	C	rs12460869	23648065	3.58E-05	Recessive model	1.83	[1.37-2.46]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs12460869-T	Research Support, Non-U.S. Gov't
19	29784673	rs7408479	A	G	rs7408479	23648065	8.69E-05	Allelic model	1.83	[1.36-2.46]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7408479-T	Research Support, Non-U.S. Gov't
19	30920536	rs7247381	T	C	rs7247381	23648065	8.60E-05	Recessive model	1.5	[1.22-1.84]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7247381-G	Research Support, Non-U.S. Gov't
19	30937843	rs33428	A	G	rs33428	23648065	3.00E-06	Dominant model	1.38	[1.16-1.63]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs33428-G	Research Support, Non-U.S. Gov't
19	49610389	rs3795055	T	C	rs3795055	23648065	4.74E-05	Dominant model	1.56	[1.20-2.03]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs3795055-G	Research Support, Non-U.S. Gov't
19	50483541	rs16981612	C	T	rs16981612	23648065	6.03E-05	Dominant model	1.72	[1.29-2.31]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs16981612-C	Research Support, Non-U.S. Gov't
19	50540471	rs11883067	G	A	rs11883067	23648065	2.68E-05	Dominant model	1.76	[1.31-2.36]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11883067-G	Research Support, Non-U.S. Gov't
19	56900486	rs9636161	C	T	rs9636161	23648065	7.12E-05	Dominant model	2.65	[1.60-4.40]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9636161-G	Research Support, Non-U.S. Gov't
19	58830261	rs7359922	T	C	rs7359922	23648065	1.27E-05	Allelic model	2.96	[1.82-4.82]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7359922-G	Research Support, Non-U.S. Gov't
20	344079	rs6037430	T	C	rs6037430	23648065	9.74E-06	Allelic model	3.11	[1.81-5.36]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6037430-G	Research Support, Non-U.S. Gov't
20	934313	rs6140734	G	A	rs6140734	23648065	5.70E-05	Recessive model	1.6	[1.18-2.17]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6140734-T	Research Support, Non-U.S. Gov't
20	1175894	rs6078104	G	A	rs6078104	23648065	8.71E-05	Allelic model	3.44	[1.85-6.38]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6078104-T	Research Support, Non-U.S. Gov't
20	3630107	rs2595582	G	A	rs2595582	23648065	9.95E-05	Allelic model	1.83	[1.36-2.47]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2595582-T	Research Support, Non-U.S. Gov't
20	4731022	rs6037950	C	T	rs6037950	23648065	7.52E-05	Dominant model	1.43	[1.17-1.74]	428 Japanese ancestry cases; 743 Japanese ancestry controls	Japanese(1171)	ALL(1171)	ASN(1171)	ALL(1171)	Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6037950-C	Research Support, Non-U.S. Gov't
20	5813582	rs237084	C	T	rs237084	23648065	1.59E-05	Allelic model	1.89	[1.41-2.53]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs237084-G	Research Support, Non-U.S. Gov't
20	5821185	rs237091	G	A	rs237091	23648065	1.54E-05	Allelic model	1.89	[1.41-2.54]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs237091-C	Research Support, Non-U.S. Gov't
20	7624747	rs6086143	A	C	rs6086143	23648065	2.17E-05	Recessive model	1.3	[0.92-1.83]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6086143-A	Research Support, Non-U.S. Gov't
20	7654897	rs6055249	A	G	rs6055249	23648065	2.18E-05	Recessive model	1.32	[0.94-1.86]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6055249-G	Research Support, Non-U.S. Gov't
20	7752366	rs6077251	C	T	rs6077251	23648065	3.00E-06	Allelic model	2.07	[1.54-2.77]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6077251-T	Research Support, Non-U.S. Gov't
20	7756027	rs2092380	G	A	rs2092380	23648065	3.87E-06	Dominant model	2.01	[1.49-2.70]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2092380-T	Research Support, Non-U.S. Gov't
20	7836143	rs6077278	C	T	rs6077278	23648065	6.99E-06	Allelic model	2	[1.49-2.67]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6077278-T	Research Support, Non-U.S. Gov't
20	7838533	rs8116938	G	A	rs8116938	23648065	6.99E-06	Allelic model	2	[1.49-2.67]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs8116938-T	Research Support, Non-U.S. Gov't
20	7847156	rs16994091	C	T	rs16994091	23648065	6.99E-06	Allelic model	2	[1.49-2.67]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs16994091-A	Research Support, Non-U.S. Gov't
20	8639474	rs2076639	C	A	rs2076639	23648065	5.38E-05	Dominant model	2.42	[1.53-3.83]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2076639-C	Research Support, Non-U.S. Gov't
20	10165933	rs883382	A	G	rs883382	23648065	2.79E-05	Dominant model	5.62	[2.07-15.25]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs883382-T	Research Support, Non-U.S. Gov't
20	10183517	rs6039763	A	G	rs6039763	23648065	2.00E-06	Dominant model	5.97	[2.50-14.23]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6039763-A	Research Support, Non-U.S. Gov't
20	10197086	rs1889189	T	C	rs1889189	23648065	1.89E-05	Dominant model	5.51	[2.18-13.93]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1889189-A	Research Support, Non-U.S. Gov't
20	10198954	rs6039769	A	C	rs6039769	23648065	4.98E-05	Dominant model	6.17	[2.06-18.46]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6039769-T	Research Support, Non-U.S. Gov't
20	10975841	rs6108793	T	C	rs6108793	23648065	8.42E-05	Allelic model	1.53	[1.24-1.88]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6108793-C	Research Support, Non-U.S. Gov't
20	13134768	rs6078938	T	C	rs6078938	23648065	1.96E-05	Dominant model	2.06	[1.45-2.92]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6078938-C	Research Support, Non-U.S. Gov't
20	13143562	rs7264061	A	C	rs7264061	23648065	5.65E-05	Dominant model	1.97	[1.39-2.78]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs7264061-G	Research Support, Non-U.S. Gov't
20	16045679	rs775122	A	G	rs775122	23648065	9.03E-05	Allelic model	2.57	[1.61-4.09]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs775122-A	Research Support, Non-U.S. Gov't
20	22431290	rs11907086	A	G	rs11907086	23648065	5.38E-05	Recessive model	1.63	[1.12-2.39]	150 Japanese ancestry cases; 166 Japanese ancestry controls	Japanese(316)	ALL(316)	ASN(316)	ALL(316)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11907086-G	Research Support, Non-U.S. Gov't
20	23011468	rs11696134	A	G	rs11696134	23648065	7.50E-05	Dominant model	1.53	[1.17-2.00]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs11696134-T	Research Support, Non-U.S. Gov't
20	31366243	rs6141813	A	G	rs6141813	23648065	9.55E-05	Dominant model	1.42	[1.08-1.86]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6141813-T	Research Support, Non-U.S. Gov't
20	31402217	rs853858	G	A	rs853858	23648065	6.99E-05	Dominant model	1.45	[1.10-1.90]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs853858-A	Research Support, Non-U.S. Gov't
20	36997632	rs1780627	T	C	rs1780627	23648065	6.56E-05	Dominant model	1.55	[1.23-1.96]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1780627-T	Research Support, Non-U.S. Gov't
20	39611802	rs734532	G	A	rs734532	23648065	3.33E-05	Allelic model	2.38	[1.61-3.52]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs734532-C	Research Support, Non-U.S. Gov't
20	46566785	rs2426053	C	A	rs2426053	23648065	5.44E-05	Allelic model	1.68	[1.31-2.15]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2426053-G	Research Support, Non-U.S. Gov't
20	47110130	rs6012446	C	T	rs6012446	23648065	1.69E-05	Recessive model	1.88	[1.21-2.93]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6012446-G	Research Support, Non-U.S. Gov't
20	47110130	rs6012446	C	T	rs6012446	23648065	5.16E-05	Recessive model	1.48	[1.04-2.12]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6012446-G	Research Support, Non-U.S. Gov't
20	47144037	rs1321010	C	T	rs1321010	23648065	2.81E-05	Recessive model	1.84	[1.20-2.84]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1321010-C	Research Support, Non-U.S. Gov't
20	52551750	rs16998568	C	T	rs16998568	23648065	3.05E-05	Dominant model	2.2	[1.39-3.49]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs16998568-A	Research Support, Non-U.S. Gov't
20	54239617	rs1337245	A	G	rs1337245	23648065	6.74E-05	Allelic model	1.66	[1.30-2.12]	261 Japanese ancestry cases; 262 Japanese ancestry controls	Japanese(523)	ALL(523)	ASN(523)	ALL(523)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1337245-C	Research Support, Non-U.S. Gov't
20	55252119	rs4811724	C	T	rs4811724	23648065	4.79E-05	Recessive model	1.32	[1.01-1.72]	177 Japanese ancestry cases; 952 Japanese ancestry controls	Japanese(1129)	ALL(1129)	ASN(1129)	ALL(1129)	Adverse response to chemotherapy (neutropenia/leucopenia) (5-fluorouracil)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4811724-A	Research Support, Non-U.S. Gov't
20	59185488	rs6128870	G	A	rs6128870	23648065	2.48E-05	Recessive model	1.7	[1.27-2.29]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs6128870-A	Research Support, Non-U.S. Gov't
20	59315127	rs1202031	A	G	rs1202031	23648065	1.21E-05	Recessive model	1.53	[1.20-1.95]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1202031-C	Research Support, Non-U.S. Gov't
20	60097129	rs767725	A	G	rs767725	23648065	2.23E-05	Dominant model	1.45	[1.20-1.77]	371 Japanese ancestry cases; 825 Japanese ancestry controls	Japanese(1196)	ALL(1196)	ASN(1196)	ALL(1196)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs767725-A	Research Support, Non-U.S. Gov't
21	19481354	rs2055011	G	A	rs2055011	23648065	9.00E-06	Recessive model	1.35	[1.08-1.69]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2055011-C	Research Support, Non-U.S. Gov't
21	19481895	rs1491783	T	C	rs1491783	23648065	4.68E-05	Recessive model	1.37	[1.09-1.71]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1491783-T	Research Support, Non-U.S. Gov't
21	20740552	rs2825544	T	C	rs2825544	23648065	7.78E-05	Recessive model	1.59	[1.12-2.25]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2825544-T	Research Support, Non-U.S. Gov't
21	20773423	rs2825560	T	C	rs2825560	23648065	1.46E-05	Recessive model	1.64	[1.15-2.32]	106 Japanese ancestry cases; 187 Japanese ancestry controls	Japanese(293)	ALL(293)	ASN(293)	ALL(293)	Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2825560-T	Research Support, Non-U.S. Gov't
21	21804099	rs8133125	G	A	rs8133125	23648065	2.27E-05	Dominant model	1.61	[1.24-2.08]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs8133125-C	Research Support, Non-U.S. Gov't
21	26825565	rs2829750	G	A	rs2829750	23648065	2.58E-05	Dominant model	1.53	[1.23-1.91]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2829750-C	Research Support, Non-U.S. Gov't
21	26826514	rs8127977	T	C	rs8127977	23648065	2.00E-06	Dominant model	1.59	[1.28-1.97]	294 Japanese ancestry cases; 2,249 Japanese ancestry controls	Japanese(2543)	ALL(2543)	ASN(2543)	ALL(2543)	Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs8127977-A	Research Support, Non-U.S. Gov't
21	31460885	rs10432780	A	G	rs10432780	23648065	9.83E-05	Recessive model	1.47	[1.04-2.08]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs10432780-C	Research Support, Non-U.S. Gov't
21	33437648	rs4817450	T	C	rs4817450	23648065	2.22E-05	Recessive model	1.31	[0.95-1.81]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4817450-T	Research Support, Non-U.S. Gov't
21	37120781	rs2835123	A	G	rs2835123	23648065	9.19E-05	Dominant model	1.7	[1.23-2.33]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2835123-C	Research Support, Non-U.S. Gov't
21	40489027	rs2836891	C	T	rs2836891	23648065	4.51E-05	Recessive model	2.11	[1.36-3.28]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2836891-G	Research Support, Non-U.S. Gov't
21	41278302	rs2244189	C	T	rs2244189	23648065	4.69E-05	Allelic model	7.1	[2.53-19.92]	54 Japanese ancestry cases; 39 Japanese ancestry controls	Japanese(93)	ALL(93)	ASN(93)	ALL(93)	Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs2244189-G	Research Support, Non-U.S. Gov't
21	42105119	rs13049429	T	C	rs13049429	23648065	7.90E-05	Dominant model	2.61	[1.52-4.48]	176 Japanese ancestry cases; 471 Japanese ancestry controls	Japanese(647)	ALL(647)	ASN(647)	ALL(647)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs13049429-T	Research Support, Non-U.S. Gov't
21	42485808	rs13050861	A	G	rs13050861	23648065	5.16E-05	Allelic model	2.11	[1.48-3.03]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs13050861-G	Research Support, Non-U.S. Gov't
21	43674122	rs225376	G	C	rs225376	23648065	7.05E-05	Allelic model	2.01	[1.43-2.84]	83 Japanese ancestry cases; 370 Japanese ancestry controls	Japanese(453)	ALL(453)	ASN(453)	ALL(453)	Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs225376-C	Research Support, Non-U.S. Gov't
22	17318150	rs165611	T	C	rs165611	23648065	8.13E-05	Recessive model	2.27	[1.47-3.49]	59 Japanese ancestry cases; 155 Japanese ancestry controls	Japanese(214)	ALL(214)	ASN(214)	ALL(214)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs165611-T	Research Support, Non-U.S. Gov't
22	19692751	rs8142156	C	T	rs8142156	23648065	9.12E-05	Dominant model	2.53	[1.53-4.17]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs8142156-G	Research Support, Non-U.S. Gov't
22	19694333	rs9618670	C	T	rs9618670	23648065	9.12E-05	Dominant model	2.53	[1.53-4.17]	184 Japanese ancestry cases; 459 Japanese ancestry controls	Japanese(643)	ALL(643)	ASN(643)	ALL(643)	Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9618670-C	Research Support, Non-U.S. Gov't
22	21318433	rs756875	G	A	rs756875	23648065	6.65E-05	Dominant model	1.48	[1.13-1.92]	168 Japanese ancestry cases; 335 Japanese ancestry controls	Japanese(503)	ALL(503)	ASN(503)	ALL(503)	Adverse response to chemotherapy (neutropenia/leucopenia) (cyclophosphamide)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs756875-A	Research Support, Non-U.S. Gov't
22	31153276	rs9609078	G	A	rs9609078	23648065	4.00E-06	Allelic model	10.89	[3.53-33.61]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9609078-T	Research Support, Non-U.S. Gov't
22	33006503	rs5749471	A	C	rs5749471	23648065	1.50E-05	Dominant model	2.5	[1.63-3.85]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs5749471-A	Research Support, Non-U.S. Gov't
22	33013062	rs9621508	A	C	rs9621508	23648065	2.47E-05	Allelic model	2.46	[1.60-3.78]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs9621508-T	Research Support, Non-U.S. Gov't
22	34120608	rs239319	T	C	rs239319	23648065	1.89E-05	Dominant model	1.52	[1.20-1.93]	218 Japanese ancestry cases; 364 Japanese controls	Japanese(582)	ALL(582)	ASN(582)	ALL(582)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs239319-G	Research Support, Non-U.S. Gov't
22	35742524	rs129433	C	T	rs129433	23648065	1.03E-05	Dominant model	1.7	[1.26-2.29]	147 Japanese ancestry cases; 233 Japanese ancestry controls	Japanese(380)	ALL(380)	ASN(380)	ALL(380)	Adverse response to chemotherapy (neutropenia/leucopenia) (docetaxel)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs129433-C	Research Support, Non-U.S. Gov't
22	36517932	rs1476029	C	T	rs1476029	23648065	8.00E-06	Allelic model	6.43	[2.43-17.00]	150 Japanese ancestry cases; 166 Japanese ancestry controls	Japanese(316)	ALL(316)	ASN(316)	ALL(316)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs1476029-A	Research Support, Non-U.S. Gov't
22	47557638	rs4823603	G	A	rs4823603	23648065	6.43E-05	Recessive model	1.86	[1.26-2.76]	80 Japanese ancestry cases; 226 Japanese ancestry controls	Japanese(306)	ALL(306)	ASN(306)	ALL(306)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine)	HPOID:0001875	HPOID:0001882	Neutropenia	Leukopenia	DOID:1227	neutropenia	NA	NA	NA	NA	Neutropenia	rs4823603-C	Research Support, Non-U.S. Gov't

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Disease ID	588
Disease	neutropenia
Case	(Waiting for update.)