eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| neonatal lupus | ||||
| Disease ID | 1816 |
|---|---|
| Disease | neonatal lupus |
| Definition | A self-limited skin rash that appears in the neonatal period and usually resolves in four to six months after birth. It is caused by placental transfer of maternal autoantibodies, usually anti-Ro antibody. In a minority of cases, it is associated with congenital heart block, hepatitis, or thrombocytopenia. The mothers of the affected babies may be asymptomatic or suffer from systemic lupus erythematosus, Sjogren's syndrome, or rheumatoid arthritis. |
| Synonym | lupus erythematosus neonatal neonatal lupus erythematosus neonatal lupus erythematosus (disorder) neonatal lupus syndrome neonatal systemic lupus erythematosus |
| Orphanet | |
| UMLS | C0409979 |
| SNOMED-CT | |
| Comorbidity | UMLS | Disease | Sentences' Count(Total Sentences:6) C0149530 | congenital heart block | 2 C0040034 | thrombocytopenia | 2 C0008370 | cholestasis | 2 C0263401 | cutis marmorata | 1 C0011603 | dermatitis | 1 C1527336 | sjogren's syndrome | 1 |
| Curated Gene | (Waiting for update.) |
| Inferring Gene | (Waiting for update.) |
| Text Mined Gene | (Waiting for update.) |
| Locus | (Waiting for update.) |
| Disease ID | 1816 |
|---|---|
| Disease | neonatal lupus |
| Integrated Phenotype | (Waiting for update.) |
| Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:6) HP:0001873 | Low platelet count | 2 HP:0001396 | Cholestasis | 2 HP:0012722 | Heart block | 2 HP:0000965 | Livedo reticularis | 1 HP:0001297 | Cerebral vascular events | 1 HP:0100699 | Scarring | 1 |
| Disease ID | 1816 |
|---|---|
| Disease | neonatal lupus |
| Manually Symptom | UMLS | Name(Total Manually Symptoms:9) |
| Text Mined Symptom | UMLS | Name | Sentences' Count(Total Symptoms:4) C0018794 | heart block | 2 C0149530 | congenital heart block | 2 C0426768 | o sign | 1 C0037284 | skin lesions | 1 |
Manually Genotype(Total Text Mining Genotypes:0) |
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| (Waiting for update.) |
Text Mining Genotype(Total Genotypes:0) | |
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| (Waiting for update.) | |
All Snps(Total Genotypes:0) | |
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| (Waiting for update.) | |
GWASdb Annotation(Total Genotypes:0) | |
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| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:0) | |
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| (Waiting for update.) | |
Mapped by lexical matching(Total Items:0) |
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| (Waiting for update.) |
Mapped by homologous gene(Total Items:0) |
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| (Waiting for update.) |
| Disease ID | 1816 |
|---|---|
| Disease | neonatal lupus |
| Case | (Waiting for update.) |