eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| necrobiosis lipoidica | ||||
| Disease ID | 1892 |
|---|---|
| Disease | necrobiosis lipoidica |
| Definition | A degenerative disease of the dermal connective tissue characterized by the development of erythematous papules or nodules in the pretibial area. The papules form plaques covered with telangiectatic vessels. More than half of the affected patients have diabetes. |
| Synonym | lipoidica necrobiosis lipoidica necrobiosis nld necrobiosis lipoidica (disorder) necrobiosis lipoidica [disease/finding] necrobiosis lipoidica, nos nld - necrobiosis lipoidica |
| DOID | |
| UMLS | C0027538 |
| MeSH | |
| SNOMED-CT | |
| Comorbidity | UMLS | Disease | Sentences' Count(Total Sentences:9) C0011847 | diabetes | 1 C0003864 | arthritis | 1 C0152026 | retinal vasculitis | 1 C0011849 | diabetes mellitus | 1 C0003873 | rheumatoid arthritis | 1 C0040147 | thyroiditis | 1 C0677607 | hashimoto's thyroiditis | 1 C0011854 | diabetes mellitus type 1 | 1 C0042164 | uveitis | 1 |
| Curated Gene | (Waiting for update.) |
| Inferring Gene | (Waiting for update.) |
| Text Mined Gene | Entrez_id | Symbol | Score | Resource(Total Genes:16) 58 | ACTA1 | 2.006 | DISEASES 488 | ATP2A2 | 1.934 | DISEASES 9332 | CD163 | 2.33 | DISEASES 959 | CD40LG | 1.775 | DISEASES 64764 | CREB3L2 | 2.057 | DISEASES 2316 | FLNA | 1.316 | DISEASES 3105 | HLA-A | 1.015 | DISEASES 3605 | IL17A | 1.375 | DISEASES 4318 | MMP9 | 1.008 | DISEASES 5155 | PDGFB | 1.801 | DISEASES 51109 | RDH11 | 2.435 | DISEASES 6513 | SLC2A1 | 1.003 | DISEASES 4184 | SMCP | 2.527 | DISEASES 26136 | TES | 2.244 | DISEASES 7124 | TNF | 1.502 | DISEASES 7133 | TNFRSF1B | 2.687 | DISEASES |
| Locus | (Waiting for update.) |
| Disease ID | 1892 |
|---|---|
| Disease | necrobiosis lipoidica |
| Integrated Phenotype | (Waiting for update.) |
| Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:7) HP:0000819 | Diabetes mellitus | 1 HP:0000872 | Hashimoto's thyroiditis | 1 HP:0001369 | Arthritis | 1 HP:0000554 | Uveitis | 1 HP:0100646 | Thyroiditis | 1 HP:0001370 | Rheumatoid arthritis | 1 HP:0100847 | Pustulosis palmaris et plantaris | 1 |
| Disease ID | 1892 |
|---|---|
| Disease | necrobiosis lipoidica |
| Manually Symptom | UMLS | Name(Total Manually Symptoms:2) |
| Text Mined Symptom | (Waiting for update.) |
Manually Genotype(Total Text Mining Genotypes:0) |
|---|
| (Waiting for update.) |
Text Mining Genotype(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
All Snps(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Annotation(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
Mapped by lexical matching(Total Items:0) |
|---|
| (Waiting for update.) |
Mapped by homologous gene(Total Items:0) |
|---|
| (Waiting for update.) |
| Disease ID | 1892 |
|---|---|
| Disease | necrobiosis lipoidica |
| Case | (Waiting for update.) |