eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| myopathy | ||||
| Disease ID | 285 |
|---|---|
| Disease | myopathy |
| Manually Symptom | UMLS | Name(Total Manually Symptoms:24) C2364118 | weakness C1868690 | adrenal hypoplasia C1145670 | respiratory failure C0796110 | w syndrome C0796095 | c syndrome C0426768 | o sign C0311284 | multicentric reticulohistiocytosis C0271270 | ocular motor apraxia C0265213 | distal arthrogryposis C0263390 | scleromyxedema C0263390 | papular mucinosis C0235169 | excitability C0079734 | lymphosarcoma C0038522 | subacute inclusion body encephalitis C0033377 | ptosis C0032827 | k deficiency C0025362 | mental retardation C0024591 | malignant hyperthermia C0023241 | legionnaires' disease C0018801 | cardiac failure C0013295 | duodenal ulcer C0011603 | dermatitis C0009782 | connective tissue diseases C0004936 | mental disorders |
| Text Mined Symptom | UMLS | Name | Sentences' Count(Total Symptoms:11) C0004093 | weakness | 47 C1145670 | respiratory failure | 25 C0426768 | o sign | 7 C0005745 | ptosis | 4 C0024591 | malignant hyperthermia | 3 C0038454 | stroke | 2 C0026846 | muscle wasting | 2 C0015672 | fatigue | 1 C0025362 | mental retardation | 1 C0796095 | c syndrome | 1 C0030193 | pain | 1 |
Manually Genotype(Total Text Mining Genotypes:0) |
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| (Waiting for update.) |
Text Mining Genotype(Total Genotypes:0) | |
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| (Waiting for update.) | |
All Snps(Total Genotypes:44) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| snpId | pubmedId | geneId | geneSymbol | diseaseId | sourceId | sentence | score | Year | geneSymbol_dbSNP | CHROMOSOME | POS | REF | ALT |
| rs104894201 | 16129694 | 1410 | CRYAB | umls:C0026848 | BeFree | Nuclear import of {alpha}B-crystallin is phosphorylation-dependent and hampered by hyperphosphorylation of the myopathy-related mutant R120G. | 0.006253095 | 2005 | CRYAB | 11 | 111908934 | T | C |
| rs104894201 | 25449278 | 1410 | CRYAB | umls:C0026848 | BeFree | Expression of the myopathy-causing R120G mutant of αBC, harboring an arginine-to-glycine mutation at position 120, results in aggregate formation. | 0.006253095 | 2014 | CRYAB | 11 | 111908934 | T | C |
| rs104894201 | 21445271 | 1410 | CRYAB | umls:C0026848 | BeFree | A knock-in mouse model for the R120G mutation of αB-crystallin recapitulates human hereditary myopathy and cataracts. | 0.006253095 | 2011 | CRYAB | 11 | 111908934 | T | C |
| rs121434589 | 17005402 | 4620 | MYH2 | umls:C0026848 | BeFree | Our results provide evidence that the pathogenesis of the MyHC IIa E706K myopathy involves defective function of the mutated myosin as well as alterations in the structural integrity of all muscle cells irrespective of MyHC isoform expression. | 0.002985861 | 2006 | MYH2;MYHAS | 17 | 10535137 | C | T |
| rs121908192 | 25269795 | 2671 | GFER | umls:C0026848 | BeFree | The results of the present study allow us to provide a model for the functional defect in Erv1 R182H, which could potentially be extended to human ALR R194H and provides insights into the molecular basis of autosomal recessive myopathy. | 0.000542884 | 2015 | GFER | 16 | 1985991 | G | A |
| rs121909329 | 23349634 | 7415 | VCP | umls:C0026848 | BeFree | This stimulatory effect was lost when we used VCP mutants (R155H, R159G, and R191Q) known to cause Inclusion Body Myopathy with Paget's disease of bone and Fronto-temporal Dementia (IBMPFD) and/or familial Amyotrophic Lateral Sclerosis (ALS). | 0.026922403 | 2013 | VCP | 9 | 35065363 | C | T,G |
| rs121909330 | 17763460 | 7415 | VCP | umls:C0026848 | BeFree | We identified the p.R155C missense mutation in the VCP gene segregating in an Italian family with three affected siblings, two of whom had a progressive myopathy associated with dementia, whereas one exhibited a progressive myopathy and preclinical signs of Paget's disease of bone. | 0.026922403 | 2008 | VCP | 9 | 35065364 | G | A |
| rs121909330 | 21320982 | 7415 | VCP | umls:C0026848 | BeFree | Inclusion body myopathy with Paget disease of bone and frontotemporal dementia linked to VCP p.Arg155Cys in a Korean family. | 0.026922403 | 2011 | VCP | 9 | 35065364 | G | A |
| rs121909334 | 23349634 | 7415 | VCP | umls:C0026848 | BeFree | This stimulatory effect was lost when we used VCP mutants (R155H, R159G, and R191Q) known to cause Inclusion Body Myopathy with Paget's disease of bone and Fronto-temporal Dementia (IBMPFD) and/or familial Amyotrophic Lateral Sclerosis (ALS). | 0.026922403 | 2013 | VCP | 9 | 35065255 | C | T |
| rs122458140 | 25274776 | 10611 | PDLIM5 | umls:C0026848 | BeFree | In 2008, we identified a missense mutation in the second LIM domain of FHL1 (c.365 G>C, p.W122S) in a family with SP myopathy. | 0.000814326 | 2015 | FHL1 | X | 136207825 | G | C |
| rs122458140 | 25274776 | 2273 | FHL1 | umls:C0026848 | BeFree | Fhl1 W122S causes loss of protein function and late-onset mild myopathy. | 0.010334654 | 2015 | FHL1 | X | 136207825 | G | C |
| rs137852642 | 17276737 | 4854 | NOTCH3 | umls:C0026848 | BeFree | We have previously described a patient with cerebral autosomal-dominant arteriopathy with subcortical infarcts and leucoencephalopathy (CADASIL) caused by R133C mutation in NOTCH3 and with a concomitant myopathy caused by a G to A point mutation at base pair 5650 (5650G>A) in the gene encoding tRNA(Ala) in mitochondrial DNA (mtDNA). | 0.001085767 | 2007 | NOTCH3 | 19 | 15192242 | G | T,A |
| rs137852642 | 16807713 | 4854 | NOTCH3 | umls:C0026848 | BeFree | We have previously described a patient with CADASIL caused by a R133C mutation in the NOTCH3 gene and with a concomitant myopathy caused by a 5650G>A mutation in the MTTA gene in mitochondrial DNA (mtDNA). | 0.001085767 | 2006 | NOTCH3 | 19 | 15192242 | G | T,A |
| rs137854429 | 12493767 | 7084 | TK2 | umls:C0026848 | BeFree | Two mutations in the human TK2 gene, His-121 to Asn and Ile-212 to Asn, were recently described in patients with severe mtDNA depletion myopathy (Saada, A., Shaag, A., Mandel, H., Nevo, Y., Eriksson, S., and Elpeleg, O. | 0.005991584 | 2003 | TK2 | 16 | 66531394 | G | T |
| rs199474699 | NA | 4571 | TRNP | umls:C0026848 | CLINVAR | NA | 0.12 | NA | NA | MT | 15990 | C | T |
| rs199476140 | NA | 4572 | TRNQ | umls:C0026848 | CLINVAR | NA | 0.12 | NA | NA | MT | 4366 | - | A |
| rs267606673 | 22210628 | 7415 | VCP | umls:C0026848 | BeFree | Immunoprecipitation assays revealed an abnormal interaction between ATP7A(T994I) and p97/VCP, an ubiquitin-selective chaperone which is mutated in two autosomal dominant forms of motor neuron disease: amyotrophic lateral sclerosis and inclusion body myopathy with early-onset Paget disease and fronto-temporal dementia. | 0.026922403 | 2012 | ATP7A | X | 78029314 | C | T |
| rs267607190 | 24573684 | 23479 | ISCU | umls:C0026848 | BeFree | In this report, we uncover mechanistic insights concerning how the G50E ISCU mutation in humans leads to the development of severe ISCU myopathy, using a human cell line and yeast as the model systems. | 0.005438769 | 2014 | ISCU | 12 | 108564313 | G | A |
| rs267607486 | 19005210 | 4703 | NEB | umls:C0026848 | BeFree | Expression of the desmin-E245D mutant in myocytes displaces endogenous desmin and C-terminal nebulin from the Z-discs with a concomitant increase in the formation of intracellular aggregates, reminiscent of a major histological hallmark of desmin-related myopathies. | 0.002171535 | 2009 | DES | 2 | 219420346 | G | C |
| rs267607486 | 19005210 | 1674 | DES | umls:C0026848 | BeFree | Expression of the desmin-E245D mutant in myocytes displaces endogenous desmin and C-terminal nebulin from the Z-discs with a concomitant increase in the formation of intracellular aggregates, reminiscent of a major histological hallmark of desmin-related myopathies. | 0.022830912 | 2009 | DES | 2 | 219420346 | G | C |
| rs267607490 | 25557463 | 1674 | DES | umls:C0026848 | BeFree | We performed whole exome sequencing on two families with autosomal dominantly inherited myopathies with autophagic vacuolar pathology and surprisingly identified a p.R454W tail domain mutation and a novel p.S6W head domain mutation in desmin, DES. | 0.022830912 | 2014 | DES | 2 | 219425734 | C | T |
| rs281865507 | 12493767 | 7084 | TK2 | umls:C0026848 | BeFree | Two mutations in the human TK2 gene, His-121 to Asn and Ile-212 to Asn, were recently described in patients with severe mtDNA depletion myopathy (Saada, A., Shaag, A., Mandel, H., Nevo, Y., Eriksson, S., and Elpeleg, O. | 0.005991584 | 2003 | NA | NA | NA | NA | NA |
| rs28937594 | 24264357 | 10020 | GNE | umls:C0026848 | BeFree | Correction of the Middle Eastern M712T mutation causing GNE myopathy by trans-splicing. | 0.023946474 | 2013 | GNE | 9 | 36217399 | A | G |
| rs28937594 | 23238814 | 10020 | GNE | umls:C0026848 | BeFree | The most frequent mutation in GNE myopathy patients is the Middle Eastern founder mutation M712T. | 0.023946474 | 2013 | GNE | 9 | 36217399 | A | G |
| rs387906789 | 23349634 | 7415 | VCP | umls:C0026848 | BeFree | This stimulatory effect was lost when we used VCP mutants (R155H, R159G, and R191Q) known to cause Inclusion Body Myopathy with Paget's disease of bone and Fronto-temporal Dementia (IBMPFD) and/or familial Amyotrophic Lateral Sclerosis (ALS). | 0.026922403 | 2013 | VCP | 9 | 35065352 | G | C,A |
| rs387907074 | 22371254 | 84466 | MEGF10 | umls:C0026848 | BeFree | Screening the MEGF10 open reading frame in 190 patients with genetically unexplained myopathies revealed a heterozygous mutation, c.211C > T (p.R71W), in one additional subject with a similar clinical and histological presentation as the discovery family. | 0.120814326 | 2012 | MEGF10 | 5 | 127339214 | C | T |
| rs4149056 | 21992719 | 10599 | SLCO1B1 | umls:C0026848 | BeFree | SLCO1B1 rs4149056 polymorphism associated with statin-induced myopathy is differently distributed according to ethnicity in the Brazilian general population: Amerindians as a high risk ethnic group. | 0.136340051 | 2011 | SLCO1B1 | 12 | 21178615 | T | C |
| rs4149056 | 21243006 | 10599 | SLCO1B1 | umls:C0026848 | BeFree | Differential effect of the rs4149056 variant in SLCO1B1 on myopathy associated with simvastatin and atorvastatin. | 0.136340051 | 2012 | SLCO1B1 | 12 | 21178615 | T | C |
| rs4149056 | 21992719 | 1917 | EEF1A2 | umls:C0026848 | BeFree | SLCO1B1 rs4149056 polymorphism associated with statin-induced myopathy is differently distributed according to ethnicity in the Brazilian general population: Amerindians as a high risk ethnic group. | 0.017100838 | 2011 | SLCO1B1 | 12 | 21178615 | T | C |
| rs4149056 | 21243006 | 1917 | EEF1A2 | umls:C0026848 | BeFree | However, when subjects were stratified by statin type, the SLCO1B1 rs4149056 genotype was significantly associated with myopathy in patients who received simvastatin, but not in patients who received atorvastatin. | 0.017100838 | 2012 | SLCO1B1 | 12 | 21178615 | T | C |
| rs4149056 | 26376374 | 10599 | SLCO1B1 | umls:C0026848 | BeFree | The available evidence suggests that SLCO1B1 gene T521C polymorphism is associated with an increased risk of statin-related myopathy, especially in individuals receiving simvastatin. | 0.136340051 | 2015 | SLCO1B1 | 12 | 21178615 | T | C |
| rs4149056 | 18650507 | 10599 | SLCO1B1 | umls:C0026848 | GAD | [SLCO1B1 variants and statin-induced myopathy--a genomewide study.] | 0.136340051 | 2008 | SLCO1B1 | 12 | 21178615 | T | C |
| rs4149056 | 19642078 | 10599 | SLCO1B1 | umls:C0026848 | BeFree | Several factors increase the risk of developing statin-induced myopathy, including the single nucleotide polymorphism (SNP) rs4149056, located within the gene encoding solute carrier organic anion transporter (SLCO1B1). | 0.136340051 | 2010 | SLCO1B1 | 12 | 21178615 | T | C |
| rs57639980 | 12410397 | 1674 | DES | umls:C0026848 | BeFree | Cytoskeletal derangements in hereditary myopathy with a desmin L345P mutation. | 0.022830912 | 2002 | DES | 2 | 219421350 | T | C |
| rs57639980 | 10545598 | 1674 | DES | umls:C0026848 | BeFree | We conclude that the L345P desmin missense mutation causes myopathy by interfering in a dominant-negative manner with the dimerization-polymerization process of intermediate filament assembly. | 0.022830912 | 1999 | DES | 2 | 219421350 | T | C |
| rs57965306 | 17439987 | 1674 | DES | umls:C0026848 | BeFree | Scapuloperoneal syndrome type Kaeser and a wide phenotypic spectrum of adult-onset, dominant myopathies are associated with the desmin mutation R350P. | 0.022830912 | 2007 | DES | 2 | 219421365 | G | A,C |
| rs58912633 | 15622532 | 4000 | LMNA | umls:C0026848 | BeFree | p.S143F mutation in lamin A/C: a new phenotype combining myopathy and progeria. | 0.018497773 | 2005 | LMNA | 1 | 156130688 | C | T |
| rs58912633 | 17881656 | 4000 | LMNA | umls:C0026848 | BeFree | The S143F lamin A/C point mutation causes a phenotype combining features of myopathy and progeria. | 0.018497773 | 2007 | LMNA | 1 | 156130688 | C | T |
| rs58912633 | 18339564 | 4000 | LMNA | umls:C0026848 | BeFree | Progeria caused by a rare LMNA mutation p.S143F associated with mild myopathy and atrial fibrillation. | 0.018497773 | 2008 | LMNA | 1 | 156130688 | C | T |
| rs59026483 | 15539782 | 4000 | LMNA | umls:C0026848 | BeFree | The p.R190W mutation has been reported in different populations and may therefore be useful for analyzing the impact of a specific LMNA mutation on the phenotype of muscle disease. | 0.018497773 | 2005 | LMNA | 1 | 156134457 | C | T |
| rs62636495 | 18061454 | 1674 | DES | umls:C0026848 | BeFree | Characterization of a novel S13F desmin mutation associated with desmin myopathy and heart block in a Chinese family. | 0.022830912 | 2008 | DES | 2 | 219418500 | C | T |
| rs74315296 | 10873395 | 1376 | CPT2 | umls:C0026848 | BeFree | A variable myopathy associated with heterozygosity for the R503C mutation in the carnitine palmitoyltransferase II gene. | 0.123181358 | 2000 | CPT2 | 1 | 53211181 | C | T |
| rs74315401 | 8698234 | 5621 | PRNP | umls:C0026848 | BeFree | Besides occasional PrP plaques and modest spongiform degeneration, Tg(MoPrP-P101L) mice suffered from a myopathy and a peripheral neuropathy. | 0.001085767 | 1996 | PRNP | 20 | 4699525 | C | T |
| rs80338962 | 19290024 | 6329 | SCN4A | umls:C0026848 | BeFree | The present study is to observe in vitro the proliferation ability of the muscle cells from permanent myopathy (PM) patients of nomokalaemic periodic paralysis (normKPP), which is caused by mutations of Met1592Val in the skeletal muscle voltage gated sodium channel (SCN4A) gene on chromosome 17q23.1. | 0.001357209 | 2009 | SCN4A | 17 | 63941508 | T | C |
GWASdb Annotation(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:115) | |||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CHR | POS | SNPID | REF | ALT | ORI_SNPID | PMID | P_VALUE | P_VALUE_TEXT | OR/BETA | CI95_TEXT | GWAS_INITIAL_SAMPLE_SIZE | SUB_POPULATION | SUPER_POPULATION | GWAS_TRAIT | HPO_ID | HPO_TERM | DO_ID | DO_TERM | MESH_ID | MESH_TERM | EFO_ID | EFO_TERM | DOLITE_TERM | RISK_ALLELE | PUBLICATION_TYPE | AA | GENE_SYMBOL | TYPE | REFGENE |
| 1 | 26554096 | rs2050473 | C | G | rs2050473 | 21826682 | 5.01E-06 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G |
| 1 | 68884722 | rs10493443 | T | C | rs10493443 | 21826682 | 1.62E-04 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | T |
| 1 | 164328387 | rs9287061 | T | C | rs9287061 | 21826682 | 2.03E-06 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | C |
| 1 | 165831649 | rs4657482 | A | G | rs4657482 | 21826682 | 4.67E-06 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G |
| 1 | 167199180 | rs10494474 | C | G | rs10494474 | 21826682 | 2.60E-04 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | C |
| 1 | 214527252 | rs1472441 | G | A | rs1472441 | 21826682 | 3.42E-06 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | T |
| 1 | 214544632 | rs3002309 | A | C | rs3002309 | 21826682 | 4.29E-05 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G |
| 1 | 216722090 | rs6658528 | C | T | rs6658528 | 21826682 | 4.65E-06 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | T |
| 1 | 237990122 | rs2819742 | A | G | rs2819742 | 21386754 | 2.00E-07 | NA | 2.08 | [1.59-2.78] | 185 European ancestry cases; 732 European ancestry controls | European(917) | ALL(917) | EUR(917) | ALL(917) | Response to cerivastatin | HPOID:0003201 | Rhabdomyolysis | DOID:0080000 | muscular disease | D012206 | Rhabdomyolysis | NA | NA | Myopathy | rs2819742-G | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G |
| 1 | 238439308 | rs10495407 | G | A | rs10495407 | 21826682 | 2.10E-04 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G |
| 1 | 245654625 | rs2363902 | C | T | rs2363902 | 21826682 | 1.60E-04 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | C |
| 2 | 132095028 | rs1852556 | T | C | rs1852556 | 21826682 | 3.36E-05 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | T |
| 2 | 143795681 | rs2043931 | C | A | rs2043931 | 21826682 | 1.04E-05 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A |
| 2 | 152872455 | rs1519708 | A | G | rs1519708 | 21826682 | 2.45E-05 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A |
| 2 | 155190478 | rs2348924 | G | T | rs2348924 | 21826682 | 1.10E-04 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G |
| 2 | 175836843 | rs3771917 | T | C | rs3771917 | 21826682 | 5.25E-05 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | T |
| 2 | 182792984 | rs2303554 | T | A | rs2303554 | 21826682 | 7.48E-09 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A |
| 2 | 219537224 | rs2241527 | G | A | rs2241527 | 21826682 | 1.27E-06 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G |
| 2 | 221187549 | rs1454552 | C | T | rs1454552 | 21826682 | 3.15E-05 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A |
| 3 | 5410364 | rs4143244 | C | T | rs4143244 | 21826682 | 1.40E-04 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | C |
| 3 | 41374621 | rs9311269 | T | C | rs9311269 | 21826682 | 2.62E-05 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | C |
| 3 | 44284584 | rs9284879 | G | A | rs9284879 | 21826682 | 1.10E-04 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G |
| 3 | 106063694 | rs6777583 | C | T | rs6777583 | 21826682 | 4.06E-06 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | C |
| 3 | 176411271 | rs6779279 | T | G | rs6779279 | 21826682 | 2.00E-04 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G |
| 4 | 3066932 | rs9291159 | T | C | rs9291159 | 21826682 | 1.55E-06 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | T |
| 4 | 108584371 | rs3805343 | C | T | rs3805343 | 21826682 | 4.19E-04 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | C |
| 4 | 114505498 | rs7665102 | G | A | rs7665102 | 21826682 | 8.23E-05 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G |
| 4 | 124698977 | rs3113384 | A | G | rs3113384 | 21826682 | 3.95E-07 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A |
| 4 | 162097832 | rs1255832 | A | T | rs1255832 | 21826682 | 4.32E-05 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | T |
| 5 | 36057228 | rs1287262 | C | G | rs1287262 | 21826682 | 1.50E-04 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | C |
| 5 | 37025871 | rs300064 | C | A | rs300064 | 21826682 | 1.90E-04 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | T |
| 5 | 107482854 | rs286797 | C | T | rs286797 | 21826682 | 4.70E-04 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A |
| 5 | 107531302 | rs286763 | T | C | rs286763 | 21826682 | 2.68E-06 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G |
| 5 | 107534886 | rs2966821 | A | C | rs2966821 | 21826682 | 2.64E-04 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G |
| 5 | 110568458 | rs9285875 | T | C | rs9285875 | 21826682 | 1.55E-04 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | C |
| 5 | 147785158 | rs9325095 | T | G | rs9325095 | 21826682 | 2.78E-04 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | T |
| 5 | 148098003 | rs9325113 | C | T | rs9325113 | 21826682 | 2.50E-04 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | C |
| 5 | 151388677 | rs707165 | G | C | rs707165 | 21826682 | 3.65E-06 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | C |
| 5 | 151423814 | rs255481 | A | G | rs255481 | 21826682 | 4.14E-06 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A |
| 5 | 154843554 | rs6881846 | A | G | rs6881846 | 21826682 | 4.36E-07 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A |
| 5 | 158709277 | rs10515782 | C | T | rs10515782 | 21826682 | 1.47E-04 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | T |
| 5 | 158754195 | rs3212220 | C | A | rs3212220 | 21826682 | 1.64E-06 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G |
| 5 | 171350313 | rs839273 | A | G | rs839273 | 21826682 | 2.30E-04 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | T |
| 5 | 171969348 | rs1347155 | C | T | rs1347155 | 21826682 | 1.98E-07 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | C |
| 6 | 48942707 | rs7766357 | A | G | rs7766357 | 21826682 | 2.70E-04 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A |
| 6 | 54309237 | rs631269 | T | C | rs631269 | 21826682 | 5.05E-06 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | T |
| 6 | 65065008 | rs1922945 | A | G | rs1922945 | 21826682 | 1.50E-04 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G |
| 6 | 65187046 | rs9342288 | G | A | rs9342288 | 21826682 | 8.00E-04 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A |
| 6 | 65193820 | rs1337512 | T | G | rs1337512 | 21826682 | 8.00E-04 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G |
| 6 | 65233665 | rs3857532 | G | A | rs3857532 | 21826682 | 3.00E-04 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A |
| 6 | 65238937 | rs1337518 | C | A | rs1337518 | 21826682 | 1.22E-04 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A |
| 6 | 108095250 | rs1850654 | T | C | rs1850654 | 21826682 | 5.51E-06 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | T |
| 6 | 108382401 | rs916395 | G | A | rs916395 | 21826682 | 1.36E-04 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | C,T |
| 6 | 145164253 | rs4143179 | T | C | rs4143179 | 21826682 | 3.10E-07 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | T |
| 6 | 148217181 | rs636023 | A | G | rs636023 | 21826682 | 7.60E-07 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G |
| 7 | 7560833 | rs10486179 | G | A | rs10486179 | 21826682 | 3.00E-06 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G |
| 7 | 7659745 | rs1476647 | T | G | rs1476647 | 21826682 | 1.63E-05 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G |
| 7 | 106720167 | rs2251838 | G | A | rs2251838 | 21826682 | 2.25E-05 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A |
| 7 | 117135025 | rs4148688 | G | C | rs4148688 | 21826682 | 1.90E-04 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G |
| 7 | 117200481 | rs1896887 | G | C | rs1896887 | 21826682 | 8.91E-06 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G |
| 8 | 1008446 | rs7011999 | A | G | rs7011999 | 21826682 | 2.01E-07 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A |
| 8 | 3897678 | rs10503226 | A | T | rs10503226 | 21826682 | 1.37E-07 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | T |
| 8 | 13694367 | rs6989085 | G | A | rs6989085 | 21826682 | 3.11E-09 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A |
| 8 | 119964052 | rs2073618 | G | C | rs2073618 | 21826682 | 1.29E-05 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G |
| 8 | 127864941 | rs979965 | A | G | rs979965 | 21826682 | 1.52E-05 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | T |
| 8 | 127865119 | rs979963 | T | C | rs979963 | 21826682 | 1.32E-04 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A |
| 9 | 12224908 | rs1538514 | G | C | rs1538514 | 21826682 | 6.28E-07 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | C |
| 9 | 28911619 | rs7018863 | A | G | rs7018863 | 21826682 | 4.97E-06 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A |
| 9 | 84109865 | rs633096 | A | G | rs633096 | 21826682 | 6.40E-05 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G |
| 9 | 116519285 | rs10513213 | A | G | rs10513213 | 21826682 | 5.03E-06 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G |
| 10 | 59959530 | rs1630731 | T | G | rs1630731 | 21826682 | 2.35E-06 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A |
| 10 | 59977161 | rs2590307 | C | T | rs2590307 | 21826682 | 1.26E-07 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | T |
| 10 | 59997926 | rs2790216 | G | A | rs2790216 | 21826682 | 1.60E-04 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | C |
| 10 | 60025448 | rs2790168 | C | T | rs2790168 | 21826682 | 1.30E-04 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | T |
| 10 | 68150939 | rs2441725 | G | C | rs2441725 | 21826682 | 5.99E-06 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | C |
| 10 | 91140508 | rs2863759 | G | A | rs2863759 | 21826682 | 1.12E-06 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G |
| 10 | 97924440 | rs10509703 | G | T | rs10509703 | 21826682 | 1.26E-06 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G |
| 10 | 117531155 | rs10490918 | G | A | rs10490918 | 21826682 | 3.06E-04 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | C |
| 11 | 35286478 | rs7115246 | A | G | rs7115246 | 21826682 | 1.43E-06 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G |
| 11 | 116181859 | rs10502218 | G | A | rs10502218 | 21826682 | 4.94E-06 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | C |
| 12 | 17740910 | rs1163784 | A | G | rs1163784 | 21826682 | 1.70E-04 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G |
| 12 | 106625732 | rs1148417 | T | C | rs1148417 | 21826682 | 4.47E-11 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A |
| 12 | 106629105 | rs10507209 | A | C | rs10507209 | 21826682 | 1.65E-08 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | C,A |
| 12 | 106629105 | rs35227737 | A | ACC | rs10507209 | 21826682 | 1.65E-08 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | C,A |
| 12 | 106629989 | rs1237262 | A | G | rs1237262 | 21826682 | 2.13E-08 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | C |
| 13 | 51066623 | rs1262778 | C | T | rs1262778 | 21826682 | 3.69E-06 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G |
| 13 | 73031936 | rs10507805 | G | A | rs10507805 | 21826682 | 1.96E-07 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A |
| 13 | 89017647 | rs1074201 | G | A | rs1074201 | 21826682 | 3.84E-07 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A |
| 13 | 99607911 | rs8002389 | A | G | rs8002389 | 21826682 | 2.84E-06 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A |
| 14 | 33682005 | rs10483432 | A | G | rs10483432 | 21826682 | 2.00E-04 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G |
| 14 | 33764568 | rs8007568 | G | C | rs8007568 | 21826682 | 4.50E-06 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G |
| 15 | 49134713 | rs1544877 | C | T | rs1544877 | 21826682 | 1.40E-04 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | C |
| 15 | 78288975 | rs10519181 | G | C | rs10519181 | 21826682 | 1.70E-04 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G |
| 15 | 88735310 | rs6496469 | A | G | rs6496469 | 21826682 | 7.55E-06 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A |
| 16 | 77488112 | rs1565781 | T | C | rs1565781 | 21826682 | 1.31E-07 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | T |
| 17 | 3320406 | rs10491216 | C | T | rs10491216 | 21826682 | 1.74E-06 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A |
| 17 | 76693551 | rs10512617 | C | G | rs10512617 | 21826682 | 1.65E-05 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | C |
| 18 | 45179883 | rs10502887 | A | G | rs10502887 | 21826682 | 5.02E-05 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A |
| 18 | 47416413 | rs1787613 | G | A | rs1787613 | 21826682 | 2.32E-05 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G |
| 20 | 15103600 | rs10485517 | G | A | rs10485517 | 21826682 | 7.04E-07 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G |
| 21 | 28870360 | rs242372 | A | G | rs242372 | 21826682 | 1.60E-04 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | C |
| X | 4150894 | rs5916542 | A | T | rs5916542 | 21826682 | 2.32E-06 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A |
| X | 8341868 | rs6640079 | G | A | rs6640079 | 21826682 | 2.02E-08 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A |
| X | 22319966 | rs4130326 | G | A | rs4130326 | 21826682 | 5.31E-06 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | T |
| X | 32111579 | rs10521986 | C | T | rs10521986 | 21826682 | 3.52E-05 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | C |
| X | 33913056 | rs10522025 | A | G | rs10522025 | 21826682 | 1.90E-04 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A |
| X | 42804453 | rs205869 | C | A | rs205869 | 21826682 | 8.76E-07 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A |
| X | 42804508 | rs205870 | A | G | rs205870 | 21826682 | 2.03E-06 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G |
| X | 43551321 | rs5906974 | C | T | rs5906974 | 21826682 | 4.84E-07 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | C |
| X | 92760182 | rs5940228 | A | G | rs5940228 | 21826682 | 3.51E-07 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A |
| X | 92957480 | rs2312033 | G | C | rs2312033 | 21826682 | 9.12E-07 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | C |
| X | 102735916 | rs5987533 | C | A | rs5987533 | 21826682 | 8.00E-08 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A |
| X | 114706218 | rs1883921 | G | C | rs1883921 | 21826682 | 1.96E-07 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | G |
| X | 138156505 | rs10521793 | C | T | rs10521793 | 21826682 | 8.95E-05 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | C |
| X | 152509755 | rs5925342 | G | A | rs5925342 | 21826682 | 1.46E-06 | Severe statin-induced myopathy | NA | NA | 39 European ancestry severe statin myopathy cases; 40 European ancestry controls | European(79) | ALL(79) | EUR(79) | ALL(79) | Statin-induced myopathy | HPOID:0001637 | Abnormality of the myocardium | DOID:0080000 | muscular disease | NA | NA | NA | NA | Myopathy | NA | Research Support, N.I.H., Extramural | Research Support, Non-U.S. Gov't | A |
Mapped by lexical matching(Total Items:0) |
|---|
| (Waiting for update.) |
Mapped by homologous gene(Total Items:0) |
|---|
| (Waiting for update.) |
| Disease ID | 285 |
|---|---|
| Disease | myopathy |
| Case | (Waiting for update.) |