eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| mercury poisoning | ||||
| Disease ID | 1913 |
|---|---|
| Disease | mercury poisoning |
| Definition | Poisoning that results from chronic or acute ingestion, injection, inhalation, or skin absorption of MERCURY or MERCURY COMPOUNDS. |
| Synonym | hydrargyria hydrargyrism hydrargyrosis mercurialism mercury causing toxic effect mercury compound poisoning mercury compound poisoning (disorder) mercury or mercury compound causing toxic effect mercury pois mercury poison mercury poisoning [disease/finding] mercury poisonings mercury poisons pois mercury poisoning by compounds of mercury poisoning mercury poisoning, mercury poisonings, mercury toxic effect mercury toxic effect of mercury and its compounds toxic effect of mercury and its compounds, nos toxic effect of mercury and/or its compounds toxic effect of mercury and/or its compounds (disorder) |
| Orphanet | |
| UMLS | C0025427 |
| MeSH | |
| SNOMED-CT | |
| Comorbidity | UMLS | Disease | Sentences' Count(Total Sentences:1) |
| Curated Gene | Entrez_id | Symbol | Resource(Total Genes:1) |
| Inferring Gene | (Waiting for update.) |
| Text Mined Gene | (Waiting for update.) |
| Locus | (Waiting for update.) |
| Disease ID | 1913 |
|---|---|
| Disease | mercury poisoning |
| Integrated Phenotype | HPO | Name(Total Integrated Phenotypes:21) HP:0001919 | Acute kidney injury HP:0001250 | Seizures HP:0002572 | Episodic vomiting HP:0002094 | Dyspnea HP:0002018 | Nausea HP:0001289 | Confusion HP:0001337 | Tremor HP:0002878 | Respiratory failure HP:0002900 | Hypokalemia HP:0006515 | Interstitial pneumonitis HP:0002615 | Hypotension HP:0000822 | Hypertension HP:0001332 | Dystonia HP:0002500 | Abnormality of the cerebral white matter HP:0007185 | Loss of consciousness HP:0100785 | Insomnia HP:0002574 | Episodic abdominal pain HP:0001649 | Tachycardia HP:0003324 | Generalized muscle weakness HP:0002098 | Respiratory distress HP:0002039 | Anorexia |
| Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:3) HP:0012531 | Pain | 1 HP:0002516 | Intracranial pressure elevation | 1 HP:0001298 | Encephalopathy | 1 |
| Disease ID | 1913 |
|---|---|
| Disease | mercury poisoning |
| Manually Symptom | (Waiting for update.) |
| Text Mined Symptom | (Waiting for update.) |
Manually Genotype(Total Text Mining Genotypes:0) |
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| (Waiting for update.) |
Text Mining Genotype(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
All Snps(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Annotation(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
Mapped by lexical matching(Total Items:5) | ||||
|---|---|---|---|---|
| HP ID | HP Name | MP ID | MP Name | Annotation |
| HP:0003324 | Generalized muscle weakness | MP:0000747 | muscle weakness | loss of muscle strength |
| HP:0002500 | Abnormality of the cerebral white matter | MP:0012129 | failure of blastocyst formation | inability to form a blastocyst from a solid ball of cells known as a morula |
| HP:0001919 | Acute kidney injury | MP:0011423 | kidney cortex atrophy | acquired diminution of the size of the outer portion of the kidney located between the renal capsule and the renal medulla, associated with wasting as from death and reabsorbtion of cells, diminished cellular proliferation, decreased cellular volume, pres |
| HP:0002878 | Respiratory failure | MP:0012129 | failure of blastocyst formation | inability to form a blastocyst from a solid ball of cells known as a morula |
| HP:0002098 | Respiratory distress | MP:0001954 | respiratory distress | physical difficulty or inability to breathe; shortness of breath |
Mapped by homologous gene(Total Items:21) | ||||
|---|---|---|---|---|
| HP ID | HP Name | MP ID | MP Name | Annotation |
| HP:0002878 | Respiratory failure | MP:0020309 | increased creatine kinase activity | increased ability of to catalyze the reaction: ATP + creatine = N-phosphocreatine + ADP + 2 H(+). |
| HP:0002572 | Episodic vomiting | MP:0013600 | testis degeneration | a retrogressive impairment of function or destruction of either or both of the male reproductive glands |
| HP:0002094 | Dyspnea | MP:0014185 | cerebellum atrophy | acquired diminution of the size of the cerebellum associated with wasting as from death and reabsorption of cells, diminished cellular proliferation, decreased cellular volume, pressure, ischemia, malnutrition, reduced function or malfunction, or hormonal |
| HP:0002900 | Hypokalemia | MP:0014206 | decreased intestinal epithelial sodium ion transmembrane transport | |
| HP:0002018 | Nausea | MP:0014185 | cerebellum atrophy | acquired diminution of the size of the cerebellum associated with wasting as from death and reabsorption of cells, diminished cellular proliferation, decreased cellular volume, pressure, ischemia, malnutrition, reduced function or malfunction, or hormonal |
| HP:0100785 | Insomnia | MP:0020187 | altered susceptibility to prion infection | altered likelihood that an organism will develop ill effects from the small proteinaceous infectious particles which are resistant to inactivation by procedures that modify nucleic acids and which contain an abnormal isoform of a cellular protein that is |
| HP:0001289 | Confusion | MP:0020187 | altered susceptibility to prion infection | altered likelihood that an organism will develop ill effects from the small proteinaceous infectious particles which are resistant to inactivation by procedures that modify nucleic acids and which contain an abnormal isoform of a cellular protein that is |
| HP:0002615 | Hypotension | MP:0020214 | susceptible to malignant hyperthermia | increased susceptibility to hyperthermia triggered by exposure to certain drugs used for general anesthesia, specifically the volatile anesthetic agents and the neuromuscular blocking agent, succinylcholine |
| HP:0002098 | Respiratory distress | MP:0014198 | absent pituitary infundibular stalk | absence of the apical portion of the tubular structure extending from the hypothalamus to the posterior lobe of the pituitary gland |
| HP:0001919 | Acute kidney injury | MP:0020216 | decreased circulating complement protein level | less than normal levels of the serum proteins that act sequentially to allow for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes |
| HP:0001250 | Seizures | MP:3000003 | abnormal Ebner's gland morphology | any structural anomaly of the serous salivary glands which reside adjacent to the moats surrounding the circumvallate and foliate papillae just anterior to the posterior third of the tongue, anterior to the terminal sulcus; these exocrine glands secrete l |
| HP:0001337 | Tremor | MP:0020329 | decreased capillary density | reduction in the number of capillaries in a given cross-sectional area of a tissue |
| HP:0002574 | Episodic abdominal pain | MP:0012504 | increased forebrain apoptosis | increase in the number of cells of the forebrain undergoing programmed cell death |
| HP:0001649 | Tachycardia | MP:0020214 | susceptible to malignant hyperthermia | increased susceptibility to hyperthermia triggered by exposure to certain drugs used for general anesthesia, specifically the volatile anesthetic agents and the neuromuscular blocking agent, succinylcholine |
| HP:0003324 | Generalized muscle weakness | MP:0020234 | decreased basal metabolism | decrease in heat production of an organism at the lowest level of cell chemistry in an inactive, awake, and fasting state |
| HP:0006515 | Interstitial pneumonitis | MP:0013501 | increased fibroblast apoptosis | increase in the timing or the number of fibroblast cells undergoing programmed cell death |
| HP:0002500 | Abnormality of the cerebral white matter | MP:0020137 | decreased bone mineralization | decrease in the rate at which minerals are deposited into bone |
| HP:0001332 | Dystonia | MP:0020329 | decreased capillary density | reduction in the number of capillaries in a given cross-sectional area of a tissue |
| HP:0000822 | Hypertension | MP:0020216 | decreased circulating complement protein level | less than normal levels of the serum proteins that act sequentially to allow for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes |
| HP:0002039 | Anorexia | MP:0020137 | decreased bone mineralization | decrease in the rate at which minerals are deposited into bone |
| HP:0007185 | Loss of consciousness | MP:0011110 | preweaning lethality, incomplete penetrance | the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age) |
| Disease ID | 1913 |
|---|---|
| Disease | mercury poisoning |
| Case | (Waiting for update.) |