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	meningitis, tuberculous

Disease ID	1644
Disease	meningitis, tuberculous
Definition	A form of bacterial meningitis caused by MYCOBACTERIUM TUBERCULOSIS or rarely MYCOBACTERIUM BOVIS. The organism seeds the meninges and forms microtuberculomas which subsequently rupture. The clinical course tends to be subacute, with progressions occurring over a period of several days or longer. Headache and meningeal irritation may be followed by SEIZURES, cranial neuropathies, focal neurologic deficits, somnolence, and eventually COMA. The illness may occur in immunocompetent individuals or as an OPPORTUNISTIC INFECTION in the ACQUIRED IMMUNODEFICIENCY SYNDROME and other immunodeficiency syndromes. (From Adams et al., Principles of Neurology, 6th ed, pp717-9)
Synonym	meningeal tuberculoses meningeal tuberculosis meninges--tuberculosis meningitides, tubercular meningitides, tuberculosis meningitides, tuberculous meningitis tb meningitis tuberculosis meningitis tuberculous meningitis, tubercular meningitis, tuberculosis tb - tuberculous meningitis tb meningitides tb meningitis tb meningitis-unspec tbm - tuberculous meningitis tubercular meningitides tubercular meningitis tuberculoses, meningeal tuberculosis meningeal tuberculosis meninges tuberculosis meningitides tuberculosis meningitis tuberculosis of meninges tuberculosis of meninges (disorder) tuberculosis, meningeal tuberculosis, meningeal [disease/finding] tuberculous meningitides tuberculous meningitis tuberculous meningitis (disorder) tuberculous meningitis nos tuberculous meningitis nos (disorder) tuberculous meningitis, unspecified
DOID	DOID:9795
ICD10	ICD10CM:A17.0
UMLS	C0041318
MeSH	D014390
SNOMED-CT	SNOMEDCT_US_2016_09_01:58437007
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:36) C0020255 \| hydrocephalus \| 17 C0151740 \| raised intracranial pressure \| 2 C0040053 \| thrombosis \| 2 C0025309 \| meningoencephalitis \| 1 C0001623 \| adrenal insufficiency \| 1 C0078981 \| arachnoid cyst \| 1 C0085437 \| bacterial meningitis \| 1 C0751955 \| brain infarct \| 1 C0037198 \| sinus thrombosis \| 1 C0003864 \| arthritis \| 1 C0013182 \| drug hypersensitivity \| 1 C0013421 \| dystonia \| 1 C0011849 \| diabetes mellitus \| 1 C0025297 \| viral meningitis \| 1 C1527311 \| brain edema \| 1 C0151740 \| elevated intracranial pressure \| 1 C0151311 \| cranial nerve palsy \| 1 C0011847 \| diabetes \| 1 C0151740 \| intracranial hypertension \| 1 C0041321 \| miliary tb \| 1 C0409974 \| lupus erythematosus \| 1 C0038220 \| status epilepticus \| 1 C0011854 \| type 1 diabetes mellitus \| 1 C0456909 \| vision loss \| 1 C0003873 \| rheumatoid arthritis \| 1 C0026769 \| multiple sclerosis \| 1 C0041327 \| pulmonary tb \| 1 C0003708 \| arachnoiditis \| 1 C0011880 \| diabetic ketoacidosis \| 1 C0011854 \| type 1 diabetes \| 1 C0039144 \| syringomyelia \| 1 C0020538 \| hypertension \| 1 C1565489 \| renal insufficiency \| 1 C0041296 \| tuberculosis \| 1 C0042384 \| angiitis \| 1 C0024141 \| systemic lupus erythematosus \| 1
Curated Gene	(Waiting for update.)
Inferring Gene	Entrez_id \| Symbol \| Resource(Total Genes:1) 7097 \| TLR2 \| CIPHER
Text Mined Gene	(Waiting for update.)
Locus	(Waiting for update.)

Disease ID	1644
Disease	meningitis, tuberculous
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:40) HP:0000238 \| Nonsyndromal hydrocephalus \| 18 HP:0001297 \| Cerebral vascular events \| 7 HP:0001945 \| Fever \| 3 HP:0001259 \| Coma \| 3 HP:0006824 \| Cranial nerve palsy \| 2 HP:0001250 \| Seizures \| 2 HP:0002721 \| Immunodeficiency \| 2 HP:0002138 \| Subarachnoid hemorrhage \| 1 HP:0100543 \| Cognitive deficits \| 1 HP:0000846 \| Hypoadrenalism \| 1 HP:0100702 \| Arachnoid cyst \| 1 HP:0002725 \| Systemic lupus erythematosus \| 1 HP:0001332 \| Dystonia \| 1 HP:0000822 \| Hypertension \| 1 HP:0002410 \| Aqueductal stenosis \| 1 HP:0011986 \| Ectopic bone formation \| 1 HP:0001953 \| Diabetic ketosis \| 1 HP:0000083 \| Renal insufficiency \| 1 HP:0005305 \| Cerebral vein thrombosis \| 1 HP:0002716 \| Lymph node hyperplasia \| 1 HP:0100661 \| Trigeminal neuralgia \| 1 HP:0000234 \| Head abnormality \| 1 HP:0000505 \| Poor vision \| 1 HP:0002315 \| Headaches \| 1 HP:0001269 \| Hemiparesis \| 1 HP:0000819 \| Diabetes mellitus \| 1 HP:0001370 \| Rheumatoid arthritis \| 1 HP:0004936 \| Blood clot in vein \| 1 HP:0000572 \| Visual loss \| 1 HP:0012089 \| Arteritis \| 1 HP:0001289 \| Confusion \| 1 HP:0002181 \| Cerebral edema \| 1 HP:0002516 \| Intracranial pressure elevation \| 1 HP:0000969 \| Dropsy \| 1 HP:0001291 \| Cranial nerve disease \| 1 HP:0002633 \| Vasculitis \| 1 HP:0002133 \| Status epilepticus \| 1 HP:0001369 \| Arthritis \| 1 HP:0004326 \| Cachexia \| 1 HP:0003396 \| Syringomyelia \| 1

Disease ID	1644
Disease	meningitis, tuberculous
Manually Symptom	(Waiting for update.)
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:9) C0020255 \| hydrocephalus \| 13 C0038454 \| stroke \| 6 C0041295 \| tuberculoma \| 4 C0151740 \| raised intracranial pressure \| 2 C0041296 \| tuberculosis \| 2 C0043046 \| wasting syndrome \| 1 C0151740 \| intracranial hypertension \| 1 C0549423 \| obstructive hydrocephalus \| 1 C0021308 \| infarction \| 1

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

Text Mining Genotype(Total Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:0)
(Waiting for update.)

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Disease ID	1644
Disease	meningitis, tuberculous
Case	(Waiting for update.)

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