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	malaria

Disease ID	180
Disease	malaria
Definition	A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia.
Synonym	[x]unspecified malaria [x]unspecified malaria (disorder) disease caused by plasmodiidae disease caused by plasmodiidae (disorder) disease due to plasmodiidae disease due to plasmodiidae (disorder) fever malaria fever, marsh fever, remittent infect plasmodium infection, plasmodium infections, plasmodium malaria (disorder) malaria [disease/finding] malaria fever malaria fever nos malaria nos malaria, nos malaria, unspecified malarial fever malarial fever (finding) malarias marsh fever paludism plasmodiosis plasmodium infect plasmodium infection plasmodium infections remittent fever unspecified malaria unspecified malaria (disorder)
Orphanet	ORPHANET:673
DOID	DOID:12365
ICD10	ICD10CM:B54
UMLS	C0024530
MeSH	D008288
SNOMED-CT	SNOMEDCT_US_2016_09_01:105649009;SNOMEDCT_US_2016_09_01:61462000;SNOMEDCT_US_2016_09_01:248437004
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:124) C0002871 \| anaemia \| 49 C0002871 \| anemia \| 46 C0040034 \| thrombocytopenia \| 14 C0041296 \| tuberculosis \| 11 C0024534 \| cerebral malaria \| 9 C0035078 \| renal failure \| 9 C0017920 \| g6pd deficiency \| 8 C1704437 \| respiratory distress syndrome \| 7 C0035309 \| retinopathy \| 7 C0035222 \| acute respiratory distress syndrome \| 6 C0022660 \| acute renal failure \| 6 C0024535 \| falciparum malaria \| 5 C0037998 \| splenic infarction \| 5 C0004623 \| bacterial infection \| 4 C0001339 \| acute pancreatitis \| 4 C0025289 \| meningitis \| 4 C0019045 \| haemoglobinopathies \| 4 C0024530 \| malaria \| 3 C0037054 \| sickle cell trait \| 3 C0039730 \| thalassemia \| 3 C0747256 \| parasitic infection \| 3 C0024530 \| plasmodium infection \| 3 C0162429 \| malnutrition \| 3 C0002878 \| hemolytic anemia \| 3 C0011603 \| dermatitis \| 2 C0010674 \| cystic fibrosis \| 2 C0012739 \| disseminated intravascular coagulation \| 2 C0004623 \| bacterial infections \| 2 C0022672 \| acute tubular necrosis \| 2 C0030499 \| parasitic diseases \| 2 C0040188 \| tic disorders \| 2 C0034063 \| pulmonary oedema \| 2 C0024537 \| vivax malaria \| 2 C0000786 \| miscarriage \| 2 C0011615 \| atopic dermatitis \| 2 C0030499 \| parasitic disease \| 2 C0036323 \| schistosomiasis \| 2 C0014544 \| epilepsy \| 2 C0035222 \| adult respiratory distress syndrome \| 2 C0011991 \| diarrhoea \| 2 C0002878 \| haemolytic anaemia \| 2 C0162316 \| iron deficiency anemia \| 2 C0039128 \| syphilis \| 2 C0019061 \| hemolytic uremic syndrome \| 2 C0035222 \| adult respiratory distress syndrome (ards) \| 2 C0030305 \| pancreatitis \| 2 C0019163 \| hepatitis b infection \| 1 C0151740 \| raised intracranial pressure \| 1 C0042769 \| viral infection \| 1 C0016629 \| fowlpox \| 1 C0162429 \| undernourished \| 1 C0000786 \| spontaneous abortion \| 1 C0019158 \| hepatitis \| 1 C0011847 \| diabetes \| 1 C0012739 \| disseminated intravascular coagulation (dic) \| 1 C0019163 \| hepatitis b \| 1 C0014057 \| japanese encephalitis \| 1 C0079731 \| b-cell lymphoma \| 1 C1565662 \| acute renal insufficiency \| 1 C0022658 \| nephropathy \| 1 C0025637 \| methemoglobinemia \| 1 C0004623 \| bacterial disease \| 1 C0403416 \| crescentic glomerulonephritis \| 1 C0005681 \| blackwater fever \| 1 C0006413 \| burkitt's lymphoma \| 1 C0020598 \| hypoglycemia \| 1 C0002895 \| sickle cell anemia \| 1 C0022354 \| cholestatic jaundice \| 1 C0036472 \| tsutsugamushi \| 1 C0011127 \| decubitus \| 1 C0032371 \| polio \| 1 C0035309 \| retinopathies \| 1 C0042769 \| virus infection \| 1 C0026769 \| multiple sclerosis \| 1 C0020456 \| hyperglycaemia \| 1 C0037280 \| infestation \| 1 C0039730 \| thalassaemia \| 1 C0040053 \| thrombosis \| 1 C0024535 \| plasmodium falciparum malaria \| 1 C0021053 \| immune disease \| 1 C0015230 \| rash \| 1 C0149931 \| migraines \| 1 C0155765 \| microangiopathy \| 1 C0019045 \| hemoglobin disorders \| 1 C0034063 \| pulmonary edema \| 1 C0041466 \| typhoid \| 1 C0014038 \| encephalitis \| 1 C0024299 \| lymphoma \| 1 C0019204 \| hepatocellular carcinoma \| 1 C0013395 \| indigestion \| 1 C0032285 \| lung inflammation \| 1 C0008370 \| cholestasis \| 1 C0036319 \| schistosoma mansoni \| 1 C0013537 \| eclampsia \| 1 C0039614 \| tetanus \| 1 C0020598 \| hypoglycaemia \| 1 C0042109 \| urticaria \| 1 C0019045 \| hemoglobinopathy \| 1 C0162429 \| undernutrition \| 1 C0026975 \| myelitis \| 1 C0026946 \| fungal infection \| 1 C0015464 \| facial nerve palsy \| 1 C0036117 \| salmonella infect \| 1 C0000786 \| spontaneous abortions \| 1 C1527311 \| brain edema \| 1 C0042769 \| viral infections \| 1 C0019100 \| dengue hemorrhagic fever \| 1 C0020455 \| hypergammaglobulinemia \| 1 C0002438 \| amoebiasis \| 1 C0001125 \| lactic acidosis \| 1 C0037198 \| sinus thrombosis \| 1 C0026896 \| myasthenia gravis \| 1 C0017920 \| glucose-6-phosphate dehydrogenase deficiency \| 1 C0013884 \| lymphatic filariasis \| 1 C0036117 \| salmonella infection \| 1 C0243010 \| viral encephalitis \| 1 C0011991 \| diarrhea \| 1 C1565489 \| renal insufficiency \| 1 C0036117 \| salmonella infections \| 1 C0023530 \| leukopenia \| 1 C0456909 \| blindness \| 1 C0019048 \| hemoglobinuria \| 1 C0162429 \| poor nutrition \| 1 C0034065 \| pulmonary embolism \| 1
Curated Gene	Entrez_id \| Symbol \| Resource(Total Genes:21) 7124 \| TNF \| CTD_human 6521 \| SLC4A1 \| CTD_human 4843 \| NOS2 \| CTD_human 1401 \| CRP \| CTD_human 1378 \| CR1 \| CTD_human 3383 \| ICAM1 \| CTD_human 1012 \| CDH13 \| GWASCAT 948 \| CD36 \| CTD_human 2213 \| FCGR2B \| CTD_human 256892 \| OR51F1 \| GWASCAT 114609 \| TIRAP \| CTD_human 91752 \| ZNF804A \| GWASCAT 1154 \| CISH \| CTD_human 3240 \| HP \| CTD_human 2995 \| GYPC \| CTD_human 2532 \| ACKR1 \| CTD_human 28 \| ABO \| GWASCAT 259197 \| NCR3 \| CTD_human 2993 \| GYPA \| CTD_human 4055 \| LTBR \| CTD_human 493 \| ATP2B4 \| GWASCAT
Inferring Gene	Entrez_id \| Symbol \| Resource(Total Genes:67) 5243 \| ABCB1 \| CIPHER 28 \| ABO \| CIPHER 199 \| AIF1 \| CIPHER 534 \| ATP6V1G2 \| CIPHER 948 \| CD36 \| CIPHER;CTD_human 959 \| CD40LG \| CIPHER 1378 \| CR1 \| CIPHER;CTD_human 1555 \| CYP2B6 \| CIPHER 1558 \| CYP2C8 \| CIPHER 1576 \| CYP3A4 \| CIPHER 1577 \| CYP3A5 \| CIPHER 1644 \| DDC \| CIPHER 2212 \| FCGR2A \| CIPHER 2214 \| FCGR3A \| CIPHER 2215 \| FCGR3B \| CIPHER 2539 \| G6PD \| CIPHER 2778 \| GNAS \| CIPHER 2995 \| GYPC \| CIPHER;CTD_human 3043 \| HBB \| CIPHER 3077 \| HFE \| CIPHER 3105 \| HLA-A \| CIPHER 3106 \| HLA-B \| CIPHER 3119 \| HLA-DQB1 \| CIPHER 3123 \| HLA-DRB1 \| CIPHER 3383 \| ICAM1 \| CIPHER;CTD_human 3439 \| IFNA1 \| CIPHER 3440 \| IFNA2 \| CIPHER 3454 \| IFNAR1 \| CIPHER 3456 \| IFNB1 \| CIPHER 3458 \| IFNG \| CIPHER 3586 \| IL10 \| CIPHER 3557 \| IL1RN \| CIPHER 3565 \| IL4 \| CIPHER 3659 \| IRF1 \| CIPHER 3809 \| KIR2DS4 \| CIPHER 3811 \| KIR3DL1 \| CIPHER 3813 \| KIR3DS1 \| CIPHER 7940 \| LST1 \| CIPHER 4049 \| LTA \| CIPHER 4050 \| LTB \| CIPHER 4153 \| MBL2 \| CIPHER 4277 \| MICB \| CIPHER 4282 \| MIF \| CIPHER 4621 \| MYH3 \| CIPHER 259197 \| NCR3 \| CIPHER;CTD_human 4795 \| NFKBIL1 \| CIPHER 4842 \| NOS1 \| CIPHER 4843 \| NOS2 \| CIPHER;CTD_human 283111 \| OR51V1 \| CIPHER 5175 \| PECAM1 \| CIPHER 6006 \| RHCE \| CIPHER 6341 \| SCO1 \| CIPHER 6401 \| SELE \| CIPHER 7097 \| TLR2 \| CIPHER 7099 \| TLR4 \| CIPHER 54106 \| TLR9 \| CIPHER 7124 \| TNF \| CIPHER;CTD_human 7167 \| TPI1 \| CIPHER 1401 \| CRP \| CTD_human 6521 \| SLC4A1 \| CTD_human 114609 \| TIRAP \| CTD_human 1154 \| CISH \| CTD_human 2532 \| ACKR1 \| CTD_human 2993 \| GYPA \| CTD_human 4055 \| LTBR \| CTD_human 3240 \| HP \| CTD_human 2213 \| FCGR2B \| CTD_human
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:429) 19 \| ABCA1 \| 1.089 \| DISEASES 100 \| ADA \| 1.057 \| DISEASES 11093 \| ADAMTS13 \| 2.279 \| DISEASES 130 \| ADH6 \| 1.524 \| DISEASES 55256 \| ADI1 \| 2.912 \| DISEASES 9447 \| AIM2 \| 1.03 \| DISEASES 204 \| AK2 \| 1.569 \| DISEASES 8165 \| AKAP1 \| 1.3 \| DISEASES 8852 \| AKAP4 \| 1.373 \| DISEASES 9465 \| AKAP7 \| 1.392 \| DISEASES 1646 \| AKR1C2 \| 5.764 \| DISEASES 210 \| ALAD \| 1.873 \| DISEASES 5832 \| ALDH18A1 \| 2.771 \| DISEASES 240 \| ALOX5 \| 1.119 \| DISEASES 250 \| ALPP \| 2.888 \| DISEASES 262 \| AMD1 \| 2.367 \| DISEASES 284 \| ANGPT1 \| 2.593 \| DISEASES 307 \| ANXA4 \| 2.785 \| DISEASES 310 \| ANXA7 \| 1.315 \| DISEASES 80830 \| APOL6 \| 1.74 \| DISEASES 10425 \| ARIH2 \| 1.109 \| DISEASES 415 \| ARSE \| 1.344 \| DISEASES 340075 \| ARSI \| 2.464 \| DISEASES 220202 \| ATOH7 \| 1.725 \| DISEASES 493 \| ATP2B4 \| 2.894 \| DISEASES 522 \| ATP5J \| 1.373 \| DISEASES 545 \| ATR \| 1.9 \| DISEASES 551 \| AVP \| 1.22 \| DISEASES 158835 \| AWAT2 \| 2.535 \| DISEASES 567 \| B2M \| 1.61 \| DISEASES 682 \| BSG \| 2.961 \| DISEASES 55727 \| BTBD7 \| 2.583 \| DISEASES 9184 \| BUB3 \| 1.814 \| DISEASES 64115 \| C10orf54 \| 2.542 \| DISEASES 720 \| C4A \| 2.006 \| DISEASES 721 \| C4B \| 1.063 \| DISEASES 728 \| C5AR1 \| 2.021 \| DISEASES 765 \| CA6 \| 2.391 \| DISEASES 766 \| CA7 \| 2.364 \| DISEASES 785 \| CACNB4 \| 1.326 \| DISEASES 23705 \| CADM1 \| 1.516 \| DISEASES 801 \| CALM1 \| 2.849 \| DISEASES 811 \| CALR \| 1.126 \| DISEASES 834 \| CASP1 \| 1.663 \| DISEASES 55871 \| CBWD1 \| 1.334 \| DISEASES 283234 \| CCDC88B \| 1.599 \| DISEASES 6364 \| CCL20 \| 1.912 \| DISEASES 6349 \| CCL3L1 \| 1.287 \| DISEASES 414062 \| CCL3L3 \| 1.615 \| DISEASES 388372 \| CCL4L1 \| 2.891 \| DISEASES 6354 \| CCL7 \| 2.689 \| DISEASES 9236 \| CCPG1 \| 1.58 \| DISEASES 9332 \| CD163 \| 1.711 \| DISEASES 930 \| CD19 \| 1.656 \| DISEASES 912 \| CD1D \| 3.189 \| DISEASES 914 \| CD2 \| 3.644 \| DISEASES 29126 \| CD274 \| 1.584 \| DISEASES 958 \| CD40 \| 2.541 \| DISEASES 959 \| CD40LG \| 5.165 \| DISEASES 960 \| CD44 \| 2.101 \| DISEASES 961 \| CD47 \| 1.041 \| DISEASES 966 \| CD59 \| 1.242 \| DISEASES 9308 \| CD83 \| 1.351 \| DISEASES 942 \| CD86 \| 3.101 \| DISEASES 4267 \| CD99 \| 1.361 \| DISEASES 752014 \| CEMP1 \| 1.077 \| DISEASES 1058 \| CENPA \| 1.751 \| DISEASES 1118 \| CHIT1 \| 2.506 \| DISEASES 7122 \| CLDN5 \| 1.257 \| DISEASES 283420 \| CLEC9A \| 2.399 \| DISEASES 1192 \| CLIC1 \| 1.598 \| DISEASES 8418 \| CMAHP \| 2.487 \| DISEASES 51004 \| COQ6 \| 1.712 \| DISEASES 8532 \| CPZ \| 1.953 \| DISEASES 1378 \| CR1 \| 4.173 \| DISEASES 1380 \| CR2 \| 1.33 \| DISEASES 1429 \| CRYZ \| 2.29 \| DISEASES 1506 \| CTRL \| 1.287 \| DISEASES 1508 \| CTSB \| 1.475 \| DISEASES 57703 \| CWC22 \| 2.794 \| DISEASES 2919 \| CXCL1 \| 1.388 \| DISEASES 2920 \| CXCL2 \| 1.205 \| DISEASES 4283 \| CXCL9 \| 3.355 \| DISEASES 2833 \| CXCR3 \| 2.889 \| DISEASES 1544 \| CYP1A2 \| 2.056 \| DISEASES 1555 \| CYP2B6 \| 3.012 \| DISEASES 1557 \| CYP2C19 \| 2.562 \| DISEASES 1558 \| CYP2C8 \| 3.393 \| DISEASES 1565 \| CYP2D6 \| 2.768 \| DISEASES 1576 \| CYP3A4 \| 2.979 \| DISEASES 9267 \| CYTH1 \| 1.793 \| DISEASES 7919 \| DDX39B \| 1.914 \| DISEASES 51428 \| DDX41 \| 4.269 \| DISEASES 245910 \| DEFB107A \| 2.024 \| DISEASES 503614 \| DEFB107B \| 2.024 \| DISEASES 1719 \| DHFR \| 4.984 \| DISEASES 1660 \| DHX9 \| 1.756 \| DISEASES 28514 \| DLL1 \| 1.424 \| DISEASES 7266 \| DNAJC7 \| 1.524 \| DISEASES 728489 \| DNLZ \| 1.811 \| DISEASES 1785 \| DNM2 \| 1.128 \| DISEASES 1805 \| DPT \| 2.15 \| DISEASES 1826 \| DSCAM \| 1.226 \| DISEASES 10969 \| EBNA1BP2 \| 1.215 \| DISEASES 1906 \| EDN1 \| 1.198 \| DISEASES 1915 \| EEF1A1 \| 1.142 \| DISEASES 8663 \| EIF3C \| 1.194 \| DISEASES 1974 \| EIF4A2 \| 1.942 \| DISEASES 1981 \| EIF4G1 \| 1.072 \| DISEASES 1984 \| EIF5A \| 1.701 \| DISEASES 2013 \| EMP2 \| 1.29 \| DISEASES 5167 \| ENPP1 \| 2.642 \| DISEASES 2035 \| EPB41 \| 3.922 \| DISEASES 255324 \| EPGN \| 2.557 \| DISEASES 711 \| ERC2-IT1 \| 2.236 \| DISEASES 114625 \| ERMAP \| 2.525 \| DISEASES 2098 \| ESD \| 1.972 \| DISEASES 132884 \| EVC2 \| 2.918 \| DISEASES 2152 \| F3 \| 2.192 \| DISEASES 9679 \| FAM53B \| 1.088 \| DISEASES 84188 \| FAR1 \| 1.029 \| DISEASES 355 \| FAS \| 1.975 \| DISEASES 356 \| FASLG \| 1.592 \| DISEASES 2209 \| FCGR1A \| 1.925 \| DISEASES 2213 \| FCGR2B \| 2.336 \| DISEASES 2214 \| FCGR3A \| 1.946 \| DISEASES 2219 \| FCN1 \| 1.24 \| DISEASES 2224 \| FDPS \| 2.309 \| DISEASES 2232 \| FDXR \| 2.647 \| DISEASES 11153 \| FICD \| 1.891 \| DISEASES 2280 \| FKBP1A \| 1.809 \| DISEASES 642489 \| FKBP1C \| 1.904 \| DISEASES 2316 \| FLNA \| 2.565 \| DISEASES 342184 \| FMN1 \| 1.219 \| DISEASES 2309 \| FOXO3 \| 1.048 \| DISEASES 50943 \| FOXP3 \| 3.402 \| DISEASES 166752 \| FREM3 \| 1.097 \| DISEASES 23732 \| FRRS1L \| 1.78 \| DISEASES 5348 \| FXYD1 \| 3.385 \| DISEASES 2533 \| FYB \| 3.63 \| DISEASES 2539 \| G6PD \| 1.2 \| DISEASES 645073 \| GAGE12G \| 2.366 \| DISEASES 8833 \| GMPS \| 1.857 \| DISEASES 29889 \| GNL2 \| 1.17 \| DISEASES 2804 \| GOLGB1 \| 1.837 \| DISEASES 2805 \| GOT1 \| 1.098 \| DISEASES 29933 \| GPR132 \| 2.363 \| DISEASES 2876 \| GPX1 \| 1.027 \| DISEASES 56850 \| GRIPAP1 \| 1.565 \| DISEASES 2934 \| GSN \| 1.31 \| DISEASES 2950 \| GSTP1 \| 1.043 \| DISEASES 2971 \| GTF3A \| 1.038 \| DISEASES 23560 \| GTPBP4 \| 1.369 \| DISEASES 2993 \| GYPA \| 5.058 \| DISEASES 2994 \| GYPB \| 3.272 \| DISEASES 3029 \| HAGH \| 1.268 \| DISEASES 3039 \| HBA1 \| 1.858 \| DISEASES 3043 \| HBB \| 3.368 \| DISEASES 3045 \| HBD \| 1.731 \| DISEASES 3047 \| HBG1 \| 1.065 \| DISEASES 8359 \| HIST1H4A \| 1.611 \| DISEASES 8366 \| HIST1H4B \| 1.611 \| DISEASES 8364 \| HIST1H4C \| 1.611 \| DISEASES 8360 \| HIST1H4D \| 1.61 \| DISEASES 8367 \| HIST1H4E \| 1.611 \| DISEASES 8361 \| HIST1H4F \| 1.611 \| DISEASES 8294 \| HIST1H4I \| 1.611 \| DISEASES 8363 \| HIST1H4J \| 1.611 \| DISEASES 8362 \| HIST1H4K \| 1.611 \| DISEASES 8368 \| HIST1H4L \| 1.611 \| DISEASES 8337 \| HIST2H2AA3 \| 2.339 \| DISEASES 8338 \| HIST2H2AC \| 2.339 \| DISEASES 8349 \| HIST2H2BE \| 3.316 \| DISEASES 8370 \| HIST2H4A \| 1.611 \| DISEASES 554313 \| HIST2H4B \| 1.611 \| DISEASES 121504 \| HIST4H4 \| 1.611 \| DISEASES 3105 \| HLA-A \| 2.01 \| DISEASES 3106 \| HLA-B \| 2.101 \| DISEASES 3119 \| HLA-DQB1 \| 1.633 \| DISEASES 3120 \| HLA-DQB2 \| 1.746 \| DISEASES 3123 \| HLA-DRB1 \| 2.163 \| DISEASES 3133 \| HLA-E \| 1.741 \| DISEASES 3135 \| HLA-G \| 1.497 \| DISEASES 3141 \| HLCS \| 3.134 \| DISEASES 51155 \| HN1 \| 1.673 \| DISEASES 3240 \| HP \| 4.403 \| DISEASES 3250 \| HPR \| 1.529 \| DISEASES 3269 \| HRH1 \| 2.629 \| DISEASES 3274 \| HRH2 \| 1.173 \| DISEASES 9953 \| HS3ST3B1 \| 2.159 \| DISEASES 7923 \| HSD17B8 \| 1.551 \| DISEASES 3320 \| HSP90AA1 \| 2.962 \| DISEASES 3303 \| HSPA1A \| 1.368 \| DISEASES 3329 \| HSPD1 \| 1.545 \| DISEASES 3347 \| HTN3 \| 1.335 \| DISEASES 3376 \| IARS \| 1.369 \| DISEASES 3397 \| ID1 \| 1.712 \| DISEASES 3418 \| IDH2 \| 1.639 \| DISEASES 169355 \| IDO2 \| 1.156 \| DISEASES 3445 \| IFNA8 \| 1.819 \| DISEASES 3459 \| IFNGR1 \| 2.166 \| DISEASES 3586 \| IL10 \| 5.173 \| DISEASES 3594 \| IL12RB1 \| 1.811 \| DISEASES 3605 \| IL17A \| 2.565 \| DISEASES 3559 \| IL2RA \| 1.605 \| DISEASES 133396 \| IL31RA \| 1.502 \| DISEASES 90865 \| IL33 \| 1.331 \| DISEASES 3652 \| IPP \| 2.986 \| DISEASES 51135 \| IRAK4 \| 1.17 \| DISEASES 3665 \| IRF7 \| 1.311 \| DISEASES 122961 \| ISCA2 \| 1.581 \| DISEASES 729920 \| ISPD \| 2.842 \| DISEASES 51477 \| ISYNA1 \| 1.821 \| DISEASES 3683 \| ITGAL \| 1.35 \| DISEASES 3684 \| ITGAM \| 2.562 \| DISEASES 3725 \| JUN \| 1.199 \| DISEASES 55683 \| KANSL3 \| 1.343 \| DISEASES 3767 \| KCNJ11 \| 1.173 \| DISEASES 10945 \| KDELR1 \| 3.262 \| DISEASES 3802 \| KIR2DL1 \| 1.188 \| DISEASES 3803 \| KIR2DL2 \| 1.83 \| DISEASES 3804 \| KIR2DL3 \| 1.863 \| DISEASES 3811 \| KIR3DL1 \| 1.592 \| DISEASES 11275 \| KLHL2 \| 4.549 \| DISEASES 3824 \| KLRD1 \| 1.467 \| DISEASES 10219 \| KLRG1 \| 1.732 \| DISEASES 390792 \| KRT39 \| 1.414 \| DISEASES 3903 \| LAIR1 \| 1.372 \| DISEASES 3916 \| LAMP1 \| 1.042 \| DISEASES 138307 \| LCN8 \| 2.588 \| DISEASES 11155 \| LDB3 \| 1.214 \| DISEASES 3980 \| LIG3 \| 1.345 \| DISEASES 8825 \| LIN7A \| 1.315 \| DISEASES 142910 \| LIPJ \| 3.555 \| DISEASES 643414 \| LIPK \| 2.745 \| DISEASES 3996 \| LLGL1 \| 2.577 \| DISEASES 4049 \| LTA \| 2.851 \| DISEASES 4065 \| LY75 \| 1.206 \| DISEASES 347541 \| MAGEB5 \| 2.059 \| DISEASES 93487 \| MAPK1IP1L \| 2.424 \| DISEASES 5599 \| MAPK8 \| 1.226 \| DISEASES 116511 \| MAS1L \| 1.82 \| DISEASES 4151 \| MB \| 1.807 \| DISEASES 4153 \| MBL2 \| 1.748 \| DISEASES 4168 \| MCF2 \| 5.135 \| DISEASES 4190 \| MDH1 \| 2.538 \| DISEASES 56955 \| MEPE \| 1.586 \| DISEASES 25840 \| METTL7A \| 1.717 \| DISEASES 8972 \| MGAM \| 2.861 \| DISEASES 142678 \| MIB2 \| 2.7 \| DISEASES 284889 \| MIF-AS1 \| 3.185 \| DISEASES 284424 \| MIR7-3HG \| 1.197 \| DISEASES 283078 \| MKX \| 1.255 \| DISEASES 4318 \| MMP9 \| 1.747 \| DISEASES 4508 \| MT-ATP6 \| 2.687 \| DISEASES 4512 \| MT-CO1 \| 4.889 \| DISEASES 4513 \| MT-CO2 \| 4.089 \| DISEASES 4514 \| MT-CO3 \| 2.476 \| DISEASES 4519 \| MT-CYB \| 6.156 \| DISEASES 4534 \| MTM1 \| 2.046 \| DISEASES 4536 \| MT-ND2 \| 1.048 \| DISEASES 4538 \| MT-ND4 \| 1.511 \| DISEASES 4540 \| MT-ND5 \| 3.441 \| DISEASES 4569 \| MT-TM \| 1.599 \| DISEASES 4576 \| MT-TT \| 1.264 \| DISEASES 4609 \| MYC \| 2.229 \| DISEASES 4615 \| MYD88 \| 3.578 \| DISEASES 259197 \| NCR3 \| 1.375 \| DISEASES 4694 \| NDUFA1 \| 1.931 \| DISEASES 4720 \| NDUFS2 \| 1.985 \| DISEASES 7080 \| NKX2-1 \| 1.519 \| DISEASES 58484 \| NLRC4 \| 2.479 \| DISEASES 22861 \| NLRP1 \| 1.05 \| DISEASES 114548 \| NLRP3 \| 2.251 \| DISEASES 654364 \| NME1-NME2 \| 2.347 \| DISEASES 4843 \| NOS2 \| 2.722 \| DISEASES 246734 \| NPCDR1 \| 3.432 \| DISEASES 79716 \| NPEPL1 \| 2.339 \| DISEASES 594857 \| NPS \| 1.364 \| DISEASES 8856 \| NR1I2 \| 1.17 \| DISEASES 25936 \| NSL1 \| 4.356 \| DISEASES 4521 \| NUDT1 \| 2.078 \| DISEASES 64359 \| NXN \| 1.314 \| DISEASES 51686 \| OAZ3 \| 1.189 \| DISEASES 170392 \| OIT3 \| 1.829 \| DISEASES 4998 \| ORC1 \| 3.09 \| DISEASES 142 \| PARP1 \| 1.01 \| DISEASES 25973 \| PARS2 \| 3.028 \| DISEASES 5833 \| PCYT2 \| 1.255 \| DISEASES 5133 \| PDCD1 \| 1.13 \| DISEASES 80380 \| PDCD1LG2 \| 1.406 \| DISEASES 149420 \| PDIK1L \| 1.863 \| DISEASES 5178 \| PEG3 \| 1.469 \| DISEASES 64065 \| PERP \| 1.428 \| DISEASES 23481 \| PES1 \| 2.873 \| DISEASES 100131801 \| PET100 \| 1.47 \| DISEASES 5236 \| PGM1 \| 1.891 \| DISEASES 55276 \| PGM2 \| 1.133 \| DISEASES 57649 \| PHF12 \| 2.081 \| DISEASES 55361 \| PI4K2A \| 1.455 \| DISEASES 10026 \| PIGK \| 1.533 \| DISEASES 93183 \| PIGM \| 1.216 \| DISEASES 23533 \| PIK3R5 \| 1.461 \| DISEASES 5313 \| PKLR \| 3.711 \| DISEASES 5329 \| PLAUR \| 1.225 \| DISEASES 5447 \| POR \| 1.378 \| DISEASES 5464 \| PPA1 \| 2.169 \| DISEASES 27068 \| PPA2 \| 1.116 \| DISEASES 60490 \| PPCDC \| 1.055 \| DISEASES 5475 \| PPEF1 \| 1.379 \| DISEASES 5501 \| PPP1CC \| 1.145 \| DISEASES 56980 \| PRDM10 \| 1.838 \| DISEASES 9588 \| PRDX6 \| 1.897 \| DISEASES 5575 \| PRKAR1B \| 2.56 \| DISEASES 58531 \| PRM3 \| 1.387 \| DISEASES 5625 \| PRODH \| 1.028 \| DISEASES 11212 \| PROSC \| 1.45 \| DISEASES 51334 \| PRR16 \| 1.074 \| DISEASES 23215 \| PRRC2C \| 1.721 \| DISEASES 5738 \| PTGFRN \| 2.065 \| DISEASES 5742 \| PTGS1 \| 1.164 \| DISEASES 5788 \| PTPRC \| 1.714 \| DISEASES 10411 \| RAPGEF3 \| 1.001 \| DISEASES 11069 \| RAPGEF4 \| 1.05 \| DISEASES 25898 \| RCHY1 \| 1.943 \| DISEASES 5955 \| RCN2 \| 1.045 \| DISEASES 6007 \| RHD \| 1.419 \| DISEASES 23221 \| RHOBTB2 \| 2.063 \| DISEASES 8780 \| RIOK3 \| 2.161 \| DISEASES 23212 \| RRS1 \| 2.056 \| DISEASES 10313 \| RTN3 \| 1.999 \| DISEASES 344892 \| RTP2 \| 1.435 \| DISEASES 862 \| RUNX1T1 \| 1.254 \| DISEASES 54938 \| SARS2 \| 1.779 \| DISEASES 404552 \| SCGB1D4 \| 2.435 \| DISEASES 6401 \| SELE \| 3.474 \| DISEASES 6406 \| SEMG1 \| 1.521 \| DISEASES 57337 \| SENP7 \| 2.947 \| DISEASES 12 \| SERPINA3 \| 1.416 \| DISEASES 5269 \| SERPINB6 \| 1.423 \| DISEASES 462 \| SERPINC1 \| 2.172 \| DISEASES 10019 \| SH2B3 \| 1.231 \| DISEASES 6472 \| SHMT2 \| 2.968 \| DISEASES 6614 \| SIGLEC1 \| 1.717 \| DISEASES 140885 \| SIRPA \| 1.299 \| DISEASES 23408 \| SIRT5 \| 1.248 \| DISEASES 51548 \| SIRT6 \| 1.065 \| DISEASES 51547 \| SIRT7 \| 1.214 \| DISEASES 1811 \| SLC26A3 \| 1.193 \| DISEASES 2030 \| SLC29A1 \| 1.866 \| DISEASES 6533 \| SLC6A6 \| 1.489 \| DISEASES 9300 \| SNORD28 \| 1.996 \| DISEASES 26812 \| SNORD37 \| 1.237 \| DISEASES 26810 \| SNORD41 \| 1.505 \| DISEASES 8835 \| SOCS2 \| 1.284 \| DISEASES 6648 \| SOD2 \| 1.319 \| DISEASES 6668 \| SP2 \| 1.511 \| DISEASES 221833 \| SP8 \| 1.454 \| DISEASES 200162 \| SPAG17 \| 1.948 \| DISEASES 54558 \| SPATA6 \| 1.02 \| DISEASES 11005 \| SPINK5 \| 5.843 \| DISEASES 6708 \| SPTA1 \| 1.311 \| DISEASES 6723 \| SRM \| 1.939 \| DISEASES 27286 \| SRPX2 \| 1.36 \| DISEASES 246744 \| STH \| 2.681 \| DISEASES 140901 \| STK35 \| 2.08 \| DISEASES 8802 \| SUCLG1 \| 1.714 \| DISEASES 6818 \| SULT1A3 \| 1.076 \| DISEASES 445329 \| SULT1A4 \| 1.1 \| DISEASES 6836 \| SURF4 \| 1.587 \| DISEASES 23224 \| SYNE2 \| 1.327 \| DISEASES 6873 \| TAF2 \| 1.579 \| DISEASES 51347 \| TAOK3 \| 2.056 \| DISEASES 6892 \| TAPBP \| 1.527 \| DISEASES 80222 \| TARS2 \| 2.465 \| DISEASES 123283 \| TARSL2 \| 1.567 \| DISEASES 6942 \| TCF20 \| 1.528 \| DISEASES 7062 \| TCHH \| 2.059 \| DISEASES 6949 \| TCOF1 \| 1.155 \| DISEASES 81550 \| TDRD3 \| 1.741 \| DISEASES 7010 \| TEK \| 1.886 \| DISEASES 26136 \| TES \| 1.667 \| DISEASES 728447 \| TEX28P1 \| 5.255 \| DISEASES 653363 \| TEX28P2 \| 5.238 \| DISEASES 7018 \| TF \| 3.344 \| DISEASES 7037 \| TFRC \| 3.543 \| DISEASES 7056 \| THBD \| 2.49 \| DISEASES 353376 \| TICAM2 \| 1.463 \| DISEASES 8914 \| TIMELESS \| 2.036 \| DISEASES 114609 \| TIRAP \| 3.519 \| DISEASES 7096 \| TLR1 \| 2.564 \| DISEASES 7099 \| TLR4 \| 3.692 \| DISEASES 7100 \| TLR5 \| 1.987 \| DISEASES 10333 \| TLR6 \| 2.341 \| DISEASES 51284 \| TLR7 \| 2.651 \| DISEASES 54106 \| TLR9 \| 4.194 \| DISEASES 79022 \| TMEM106C \| 2.239 \| DISEASES 7110 \| TMF1 \| 1.046 \| DISEASES 7124 \| TNF \| 5.341 \| DISEASES 8764 \| TNFRSF14 \| 1.029 \| DISEASES 8784 \| TNFRSF18 \| 1.196 \| DISEASES 7133 \| TNFRSF1B \| 1.929 \| DISEASES 10673 \| TNFSF13B \| 1.941 \| DISEASES 7150 \| TOP1 \| 1.426 \| DISEASES 112858 \| TP53RK \| 1.177 \| DISEASES 11076 \| TPPP \| 1.105 \| DISEASES 7178 \| TPT1 \| 3.002 \| DISEASES 27095 \| TRAPPC3 \| 1.722 \| DISEASES 340205 \| TREML1 \| 1.393 \| DISEASES 85363 \| TRIM5 \| 1.628 \| DISEASES 7295 \| TXN \| 2.233 \| DISEASES 91544 \| UBXN11 \| 1.407 \| DISEASES 54600 \| UGT1A9 \| 1.293 \| DISEASES 127933 \| UHMK1 \| 1.661 \| DISEASES 8725 \| URI1 \| 3.086 \| DISEASES 81605 \| URM1 \| 2.012 \| DISEASES 7419 \| VDAC3 \| 1.807 \| DISEASES 7422 \| VEGFA \| 1.806 \| DISEASES 8876 \| VNN1 \| 3.024 \| DISEASES 8875 \| VNN2 \| 2.845 \| DISEASES 55350 \| VNN3 \| 2.264 \| DISEASES 64856 \| VWA1 \| 2.596 \| DISEASES 23038 \| WDTC1 \| 2.94 \| DISEASES 79971 \| WLS \| 1.426 \| DISEASES 7485 \| WRB \| 2.084 \| DISEASES 7504 \| XK \| 1.106 \| DISEASES 7514 \| XPO1 \| 3.396 \| DISEASES 9278 \| ZBTB22 \| 1.052 \| DISEASES 84671 \| ZNF347 \| 1.013 \| DISEASES
Locus	(Waiting for update.)

Disease ID	180
Disease	malaria
Integrated Phenotype	HPO \| Name(Total Integrated Phenotypes:16) HP:0001871 \| Abnormality of blood and blood-forming tissues HP:0001919 \| Acute kidney injury HP:0003326 \| Myalgia HP:0001873 \| Thrombocytopenia HP:0100543 \| Cognitive impairment HP:0000488 \| Retinopathy HP:0002141 \| Gait imbalance HP:0002904 \| Hyperbilirubinemia HP:0002017 \| Nausea and vomiting HP:0011227 \| Elevated C-reactive protein level HP:0001945 \| Fever HP:0002315 \| Headache HP:0004372 \| Reduced consciousness/confusion HP:0002011 \| Morphological abnormality of the central nervous system HP:0002098 \| Respiratory distress HP:0001903 \| Anemia
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:116) HP:0001903 \| Anemia \| 108 HP:0001945 \| Fever \| 104 HP:0001259 \| Coma \| 19 HP:0001873 \| Low platelet count \| 17 HP:0001250 \| Seizures \| 14 HP:0000083 \| Renal insufficiency \| 11 HP:0002098 \| Respiratory distress \| 10 HP:0000488 \| Noninflammatory retina disease \| 9 HP:0000969 \| Dropsy \| 8 HP:0001511 \| Prenatal onset growth retardation \| 7 HP:0100806 \| Sepsis \| 7 HP:0001919 \| Acute renal failure \| 7 HP:0002013 \| Emesis \| 7 HP:0000952 \| Yellow skin \| 7 HP:0001878 \| Haemolytic anaemia \| 6 HP:0001941 \| acidemia \| 6 HP:0001518 \| Small for gestational age \| 4 HP:0001622 \| Premature delivery \| 4 HP:0002721 \| Immunodeficiency \| 4 HP:0001943 \| Hypoglycemia \| 4 HP:0004395 \| Malnutrition \| 4 HP:0001287 \| Meningitis \| 4 HP:0001744 \| Splenomegaly \| 4 HP:0100033 \| Tic disorder \| 3 HP:0001289 \| Confusion \| 3 HP:0001735 \| Acute pancreatitis \| 3 HP:0100598 \| Pulmonary oedema \| 3 HP:0012531 \| Pain \| 3 HP:0002027 \| Abdominal pain \| 3 HP:0002240 \| Enlarged liver \| 3 HP:0001298 \| Encephalopathy \| 3 HP:0002315 \| Headaches \| 3 HP:0002615 \| Low blood pressure \| 3 HP:0100543 \| Cognitive deficits \| 3 HP:0001942 \| Metabolic acidosis \| 2 HP:0001891 \| Iron-deficiency anemia \| 2 HP:0005961 \| Low blood arginine levels \| 2 HP:0002018 \| Nausea \| 2 HP:0005575 \| Hemolytic-uremic syndrome \| 2 HP:0008682 \| Renal tubular necrosis \| 2 HP:0002904 \| High blood bilirubin levels \| 2 HP:0001025 \| Hives \| 2 HP:0001047 \| Atopic dermatitis \| 2 HP:0000365 \| Hearing impairment \| 2 HP:0001733 \| Pancreatic inflammation \| 2 HP:0001510 \| Growth deficiency \| 2 HP:0011947 \| Respiratory infection \| 2 HP:0000010 \| Frequent urinary tract infections \| 2 HP:0005521 \| Disseminated intravascular coagulation \| 2 HP:0012223 \| Ruptured spleen \| 2 HP:0000573 \| Retinal hemorrhage \| 1 HP:0002045 \| Abnormally low body temperature \| 1 HP:0002017 \| Nausea and vomiting \| 1 HP:0001882 \| Decreased blood leukocyte number \| 1 HP:0000855 \| Insulin resistance \| 1 HP:0003212 \| Elevated serum IgE \| 1 HP:0002039 \| Anorexia \| 1 HP:0005268 \| Spontaneous abortion \| 1 HP:0000112 \| Nephropathy \| 1 HP:0001974 \| Leukocytosis \| 1 HP:0008653 \| Crescentic glomerulonephritis \| 1 HP:0002014 \| Diarrhea \| 1 HP:0002204 \| Pulmonary embolism \| 1 HP:0001900 \| Increased hemoglobin \| 1 HP:0012119 \| Methemoglobinemia \| 1 HP:0012224 \| Circulating immune complexes \| 1 HP:0003326 \| Muscle pain \| 1 HP:0002373 \| Febrile convulsions \| 1 HP:0002913 \| Myoglobinuria \| 1 HP:0012156 \| Hemophagocytosis \| 1 HP:0001954 \| Increased body temperature, episodic \| 1 HP:0001824 \| Weight loss \| 1 HP:0003473 \| Fatigable weakness \| 1 HP:0003270 \| Distended abdomen \| 1 HP:0002960 \| Autoimmune condition \| 1 HP:0003146 \| Decreased circulating cholesterol level \| 1 HP:0012486 \| Inflammation of spinal cord \| 1 HP:0002090 \| Pneumonia \| 1 HP:0003074 \| High blood glucose \| 1 HP:0010628 \| Facial palsy, unilateral or bilateral \| 1 HP:0001396 \| Cholestasis \| 1 HP:0003470 \| Inability to move \| 1 HP:0001402 \| Hepatocellular carcinoma \| 1 HP:0002665 \| Lymphoma \| 1 HP:0002063 \| Muscle rigidity \| 1 HP:0012191 \| B-cell lymphoma \| 1 HP:0002099 \| Asthma \| 1 HP:0100601 \| Eclampsia \| 1 HP:0100758 \| Gangrene \| 1 HP:0001254 \| Lethargy \| 1 HP:0002354 \| Memory loss \| 1 HP:0002383 \| Encephalitis \| 1 HP:0001685 \| Myocardial fibrosis \| 1 HP:0100665 \| Angiooedema \| 1 HP:0000745 \| Lack of motivation \| 1 HP:0011145 \| Symptomatic seizures \| 1 HP:0002527 \| Falls \| 1 HP:0001695 \| Cardiac arrest \| 1 HP:0003256 \| Coagulopathy \| 1 HP:0002181 \| Cerebral edema \| 1 HP:0012399 \| Bedsore \| 1 HP:0011675 \| Arrhythmias \| 1 HP:0001875 \| Neutropenia \| 1 HP:0012378 \| Fatigue \| 1 HP:0030731 \| Carcinoma \| 1 HP:0004445 \| Elliptocytosis \| 1 HP:0012735 \| Coughing \| 1 HP:0012115 \| Liver inflammation \| 1 HP:0001433 \| Enlarged liver and spleen \| 1 HP:0010702 \| Hypergammaglobulinaemia \| 1 HP:0000988 \| Exanthem \| 1 HP:0001050 \| Plethora \| 1 HP:0000554 \| Uveitis \| 1 HP:0002197 \| Generalized seizures \| 1 HP:0003641 \| Hemoglobin in urine \| 1 HP:0003128 \| Lactic acidosis \| 1

Disease ID	180
Disease	malaria
Manually Symptom	UMLS \| Name(Total Manually Symptoms:107) C2712323 \| hypoglycaemia C2711227 \| hepatic steatosis C2707258 \| infections C2364133 \| infection C2364072 \| depression C2203646 \| jaundice C2186740 \| urticaria C2096315 \| headache C1963164 \| lymphopenia C1963154 \| renal failure C1963091 \| diarrhea C1962966 \| retinopathy C1839611 \| n syndrome C1801950 \| g syndrome C1548477 \| dengue fever C1393529 \| vascular complications C1384353 \| infestation C1373218 \| immunosuppression C1264047 \| abdominal lymphadenopathy C1263988 \| hemolytic disease C1096155 \| macrophage activation syndrome C1000483 \| anemia C0876991 \| hemophagocytosis C0856169 \| endothelial dysfunction C0752303 \| urological manifestations C0748159 \| pulmonary involvement C0745153 \| hypoglycemic episodes C0743841 \| febrile illness C0702094 \| agranulocytosis C0687720 \| central diabetes insipidus C0679466 \| cognitive deficits C0679225 \| multiple pathologies C0424755 \| fever C0422833 \| ent symptoms C0341697 \| renal impairment C0275524 \| mixed infection C0271930 \| anemia in pregnancy C0271711 \| spontaneous hypoglycaemia C0267373 \| intestinal bleeding C0262471 \| ent problem C0242723 \| parasitemia C0242584 \| autoimmune thrombocytopenia C0242567 \| opsoclonus C0240066 \| iron deficiency C0235031 \| neurologic symptoms C0221505 \| cerebral lesions C0162429 \| malnutrition C0162316 \| iron deficiency anemia C0155305 \| optic nerve ischemia C0151740 \| intracranial hypertension C0085650 \| purpura fulminans C0041349 \| tubulointerstitial nephritis C0041296 \| tuberculosis C0040188 \| tic disorders C0040034 \| thrombocytopenia C0039730 \| thalassemia C0039730 \| thalassaemias C0039128 \| syphilis C0038826 \| superinfection C0036572 \| seizures C0036396 \| sciatica C0035222 \| adult respiratory distress syndrome C0035222 \| acute respiratory distress syndrome C0035021 \| recurrent fever C0034063 \| pulmonary edema C0033774 \| pruritus C0033117 \| priapism C0031069 \| periodic fever C0027873 \| neuromyelitis optica C0027726 \| nephrotic syndrome C0027697 \| nephritides C0024530 \| plasmodium infection C0024291 \| hemophagocytic syndrome C0023501 \| leukemoid reaction C0022660 \| acute renal failure C0022658 \| renal disorders C0022658 \| renal disease C0022658 \| nephropathy C0022658 \| nephropathies C0022658 \| kidney disorders C0021051 \| immunodeficiency C0020649 \| hypotension C0020615 \| hypoglycemia C0020598 \| hypocalcemia C0020532 \| hypersplenism C0020455 \| hypergammaglobulinaemia C0019209 \| hepatomegaly C0019080 \| hemorrhage C0017920 \| glucose-6-phosphate dehydrogenase deficiency C0016085 \| filariasis C0014544 \| epilepsy C0014038 \| encephalitis C0013395 \| indigestion C0013369 \| dysentery C0011991 \| diarrhoea C0007760 \| cerebellar syndrome C0007758 \| cerebellar ataxia C0007222 \| cardiovascular diseases C0006625 \| cachexia C0006413 \| burkitt's lymphoma C0006035 \| borreliosis C0005779 \| coagulopathy C0004610 \| bacteremia C0002878 \| haemolytic anaemia C0002871 \| anemias C0002871 \| anaemia C0001125 \| lactic acidosis
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:52) C0009450 \| infection \| 260 C0015967 \| fever \| 103 C0021311 \| infections \| 79 C0002871 \| anemia \| 55 C0002871 \| anaemia \| 54 C0242723 \| parasitemia \| 32 C0743841 \| febrile illness \| 28 C0040034 \| thrombocytopenia \| 17 C0275524 \| mixed infection \| 14 C0036572 \| seizures \| 13 C0041296 \| tuberculosis \| 11 C0035078 \| renal failure \| 10 C0035309 \| retinopathy \| 9 C0021079 \| immunosuppression \| 7 C0022346 \| jaundice \| 7 C0162316 \| iron deficiency \| 6 C0022660 \| acute renal failure \| 6 C0004610 \| bacteremia \| 6 C0752303 \| urological manifestations \| 5 C0021051 \| immunodeficiency \| 4 C0162429 \| malnutrition \| 4 C0020649 \| hypotension \| 3 C0024530 \| plasmodium infection \| 3 C0039730 \| thalassemia \| 3 C0018681 \| headache \| 3 C0035222 \| acute respiratory distress syndrome \| 3 C0019080 \| hemorrhage \| 2 C0019209 \| hepatomegaly \| 2 C0039128 \| syphilis \| 2 C0002878 \| haemolytic anaemia \| 2 C0020598 \| hypoglycemia \| 2 C0020598 \| hypoglycaemia \| 2 C0040188 \| tic disorders \| 2 C0011991 \| diarrhoea \| 2 C0038826 \| superinfection \| 2 C0042109 \| urticaria \| 2 C0422833 \| ent symptoms \| 2 C0014544 \| epilepsy \| 2 C0022658 \| nephropathy \| 1 C0876991 \| hemophagocytosis \| 1 C1839611 \| n syndrome \| 1 C0856169 \| endothelial dysfunction \| 1 C0034063 \| pulmonary edema \| 1 C0037280 \| infestation \| 1 C0017920 \| glucose-6-phosphate dehydrogenase deficiency \| 1 C0001125 \| lactic acidosis \| 1 C0013395 \| indigestion \| 1 C0005779 \| coagulopathy \| 1 C0011991 \| diarrhea \| 1 C0162316 \| iron deficiency anemia \| 1 C0341697 \| renal impairment \| 1 C0006413 \| burkitt's lymphoma \| 1

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

Text Mining Genotype(Total Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:90)
snpId	pubmedId	geneId	geneSymbol	diseaseId	sourceId	sentence	score	Year	geneSymbol_dbSNP	CHROMOSOME	POS	REF	ALT
rs10900585	22895189	493	ATP2B4	umls:C0024530	GWASCAT	One of the loci was identified on chromosome 1q32 within the ATP2B4 gene, which encodes the main calcium pump of erythrocytes, the host cells of the pathogenic stage of malaria parasites.	0.120542884	2012	ATP2B4	1	203684896	G	T
rs11036238	19465909	283111	OR51V1	umls:C0024530	GAD	[Genome-wide and fine-resolution association analysis of malaria in West Africa.]	0.002367032	2009	NA	11	5204405	G	C
rs11036238	19465909	3043	HBB	umls:C0024530	GAD	[Genome-wide and fine-resolution association analysis of malaria in West Africa.]	0.019912403	2009	NA	11	5204405	G	C
rs11091253	23297791	6778	STAT6	umls:C0024530	BeFree	The study indicated that the STAT6 promoter polymorphism rs3024944 was associated with uncomplicated malaria, whereas the FOXP3 promoter variant rs11091253 was associated with significant P. falciparum parasitaemia levels.	0.000271442	2013	FOXP3	X	49265564	G	A
rs1126535	26448013	3552	IL1A	umls:C0024530	BeFree	A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324).	0.001085767	2016	CD40LG	X	136648396	T	C
rs1126535	26448013	959	CD40LG	umls:C0024530	BeFree	A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324).	0.004810009	2016	CD40LG	X	136648396	T	C
rs1126535	26448013	7124	TNF	umls:C0024530	BeFree	A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324).	0.157314477	2016	CD40LG	X	136648396	T	C
rs1126535	26448013	3565	IL4	umls:C0024530	BeFree	A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324).	0.009977336	2016	CD40LG	X	136648396	T	C
rs1126535	26448013	55692	LUC7L	umls:C0024530	BeFree	A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324).	0.000271442	2016	CD40LG	X	136648396	T	C
rs1126535	26448013	4843	NOS2	umls:C0024530	BeFree	A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324).	0.139445464	2016	CD40LG	X	136648396	T	C
rs1211375	26448013	7124	TNF	umls:C0024530	BeFree	A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324).	0.157314477	2016	LUC7L	16	190281	A	C
rs1211375	26448013	4843	NOS2	umls:C0024530	BeFree	A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324).	0.139445464	2016	LUC7L	16	190281	A	C
rs1211375	26448013	3565	IL4	umls:C0024530	BeFree	A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324).	0.009977336	2016	LUC7L	16	190281	A	C
rs1211375	26448013	3552	IL1A	umls:C0024530	BeFree	A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324).	0.001085767	2016	LUC7L	16	190281	A	C
rs1211375	26448013	959	CD40LG	umls:C0024530	BeFree	A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324).	0.004810009	2016	LUC7L	16	190281	A	C
rs1211375	26448013	55692	LUC7L	umls:C0024530	BeFree	A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324).	0.000271442	2016	LUC7L	16	190281	A	C
rs12212067	24035192	2309	FOXO3	umls:C0024530	BeFree	We identify a noncoding polymorphism in FOXO3A (rs12212067: T > G) at which the minor (G) allele, despite not being associated with disease susceptibility, is associated with a milder course of Crohn's disease and rheumatoid arthritis and with increased risk of severe malaria.	0.000814326	2013	FOXO3	6	108659993	T	G
rs12788102	23717212	256892	OR51F1	umls:C0024530	GWASCAT	Imputation-based meta-analysis of severe malaria in three African populations.	0.12	2013	OR51F1	11	4769345	A	G
rs1451375	19465909	1644	DDC	umls:C0024530	GAD	[Genome-wide and fine-resolution association analysis of malaria in West Africa.]	0.002638474	2009	DDC	7	50555014	C	A
rs1695	19635899	2950	GSTP1	umls:C0024530	BeFree	However, a significant association of GSTP1 I105V genotype with severe malarial anemia was discovered (26.0% against 10.3% mild malaria, P = 0.004).	0.000814326	2009	GSTP1	11	67585218	A	G
rs17561	26448013	3552	IL1A	umls:C0024530	BeFree	A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324).	0.001085767	2016	IL1A	2	112779646	C	A
rs17561	26448013	3565	IL4	umls:C0024530	BeFree	A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324).	0.009977336	2016	IL1A	2	112779646	C	A
rs17561	26448013	7124	TNF	umls:C0024530	BeFree	A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324).	0.157314477	2016	IL1A	2	112779646	C	A
rs17561	26448013	55692	LUC7L	umls:C0024530	BeFree	A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324).	0.000271442	2016	IL1A	2	112779646	C	A
rs17561	26448013	959	CD40LG	umls:C0024530	BeFree	A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324).	0.004810009	2016	IL1A	2	112779646	C	A
rs17561	26448013	4843	NOS2	umls:C0024530	BeFree	A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324).	0.139445464	2016	IL1A	2	112779646	C	A
rs1800750	26448013	4843	NOS2	umls:C0024530	BeFree	A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324).	0.139445464	2016	TNF	6	31575186	G	A
rs1800750	26448013	55692	LUC7L	umls:C0024530	BeFree	A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324).	0.000271442	2016	TNF	6	31575186	G	A
rs1800750	26448013	3552	IL1A	umls:C0024530	BeFree	A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324).	0.001085767	2016	TNF	6	31575186	G	A
rs1800750	26448013	7124	TNF	umls:C0024530	BeFree	A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324).	0.157314477	2016	TNF	6	31575186	G	A
rs1800750	26448013	959	CD40LG	umls:C0024530	BeFree	A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324).	0.004810009	2016	TNF	6	31575186	G	A
rs1800750	26448013	3565	IL4	umls:C0024530	BeFree	A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324).	0.009977336	2016	TNF	6	31575186	G	A
rs1800925	19840389	3596	IL13	umls:C0024530	BeFree	Only rs1881457 located in the promoter region of IL13, which is in linkage disequilibrium with rs1800925 (r2 = 0.73), showed a significant association with severe malaria after adjusting for multiple testing (P = 0.046 by permutation test).	0.001357209	2009	IL13;LOC101927761	5	132657117	C	T
rs1805015	26448013	959	CD40LG	umls:C0024530	BeFree	A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324).	0.004810009	2016	IL4R	16	27362859	T	C
rs1805015	26448013	3565	IL4	umls:C0024530	BeFree	A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324).	0.009977336	2016	IL4R	16	27362859	T	C
rs1805015	26448013	3552	IL1A	umls:C0024530	BeFree	A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324).	0.001085767	2016	IL4R	16	27362859	T	C
rs1805015	26448013	4843	NOS2	umls:C0024530	BeFree	A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324).	0.139445464	2016	IL4R	16	27362859	T	C
rs1805015	26448013	7124	TNF	umls:C0024530	BeFree	A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324).	0.157314477	2016	IL4R	16	27362859	T	C
rs1805015	26448013	55692	LUC7L	umls:C0024530	BeFree	A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324).	0.000271442	2016	IL4R	16	27362859	T	C
rs1881457	19840389	3596	IL13	umls:C0024530	BeFree	Only rs1881457 located in the promoter region of IL13, which is in linkage disequilibrium with rs1800925 (r2 = 0.73), showed a significant association with severe malaria after adjusting for multiple testing (P = 0.046 by permutation test).	0.001357209	2009	IL13;LOC101927761	5	132656717	A	C
rs2069705	25445652	770	CA11	umls:C0024530	BeFree	The TA11CAG haplotype (rs2069705 T/C, rs2430561 A/T, rs3138557 (CA)n, rs2069718 T/C, rs2069727 A/G, rs2069728 G/A) carrying a short CA11 repeat also exhibited very strong association with severe malaria, particularly in the endemic region (severe vs. control, OR=14.56, 95% CI=3.39-85.81, P=3 × 10(-5)).	0.000271442	2014	IFNG	12	68161231	G	A
rs2069718	25445652	770	CA11	umls:C0024530	BeFree	The TA11CAG haplotype (rs2069705 T/C, rs2430561 A/T, rs3138557 (CA)n, rs2069718 T/C, rs2069727 A/G, rs2069728 G/A) carrying a short CA11 repeat also exhibited very strong association with severe malaria, particularly in the endemic region (severe vs. control, OR=14.56, 95% CI=3.39-85.81, P=3 × 10(-5)).	0.000271442	2014	IFNG	12	68156382	A	G
rs2069727	25445652	770	CA11	umls:C0024530	BeFree	The TA11CAG haplotype (rs2069705 T/C, rs2430561 A/T, rs3138557 (CA)n, rs2069718 T/C, rs2069727 A/G, rs2069728 G/A) carrying a short CA11 repeat also exhibited very strong association with severe malaria, particularly in the endemic region (severe vs. control, OR=14.56, 95% CI=3.39-85.81, P=3 × 10(-5)).	0.000271442	2014	IFNG	12	68154443	T	C
rs2069728	25445652	770	CA11	umls:C0024530	BeFree	The TA11CAG haplotype (rs2069705 T/C, rs2430561 A/T, rs3138557 (CA)n, rs2069718 T/C, rs2069727 A/G, rs2069728 G/A) carrying a short CA11 repeat also exhibited very strong association with severe malaria, particularly in the endemic region (severe vs. control, OR=14.56, 95% CI=3.39-85.81, P=3 × 10(-5)).	0.000271442	2014	NA	12	68154004	C	T
rs2243250	26448013	3552	IL1A	umls:C0024530	BeFree	A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324).	0.001085767	2016	IL4	5	132673462	C	T
rs2243250	26448013	7124	TNF	umls:C0024530	BeFree	A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324).	0.157314477	2016	IL4	5	132673462	C	T
rs2243250	26448013	3565	IL4	umls:C0024530	BeFree	A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324).	0.009977336	2016	IL4	5	132673462	C	T
rs2243250	26448013	4843	NOS2	umls:C0024530	BeFree	A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324).	0.139445464	2016	IL4	5	132673462	C	T
rs2243250	26448013	959	CD40LG	umls:C0024530	BeFree	A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324).	0.004810009	2016	IL4	5	132673462	C	T
rs2243250	26448013	55692	LUC7L	umls:C0024530	BeFree	A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324).	0.000271442	2016	IL4	5	132673462	C	T
rs2274567	25683978	1378	CR1	umls:C0024530	BeFree	These findings suggest that CR1 gene rs2274567 G/A, rs4844600 G/A, and rs2296160 C/T polymorphisms may not be involved in susceptibility to malaria in Chinese population.	0.124267125	2015	CR1	1	207580276	A	G
rs2296160	25683978	1378	CR1	umls:C0024530	BeFree	These findings suggest that CR1 gene rs2274567 G/A, rs4844600 G/A, and rs2296160 C/T polymorphisms may not be involved in susceptibility to malaria in Chinese population.	0.124267125	2015	CR1	1	207621975	A	G
rs2430561	25445652	770	CA11	umls:C0024530	BeFree	The TA11CAG haplotype (rs2069705 T/C, rs2430561 A/T, rs3138557 (CA)n, rs2069718 T/C, rs2069727 A/G, rs2069728 G/A) carrying a short CA11 repeat also exhibited very strong association with severe malaria, particularly in the endemic region (severe vs. control, OR=14.56, 95% CI=3.39-85.81, P=3 × 10(-5)).	0.000271442	2014	IFNG	12	68158742	T	A
rs3024944	23297791	6778	STAT6	umls:C0024530	BeFree	The study indicated that the STAT6 promoter polymorphism rs3024944 was associated with uncomplicated malaria, whereas the FOXP3 promoter variant rs11091253 was associated with significant P. falciparum parasitaemia levels.	0.000271442	2013	STAT6	12	57111665	C	G
rs3138557	25445652	770	CA11	umls:C0024530	BeFree	The TA11CAG haplotype (rs2069705 T/C, rs2430561 A/T, rs3138557 (CA)n, rs2069718 T/C, rs2069727 A/G, rs2069728 G/A) carrying a short CA11 repeat also exhibited very strong association with severe malaria, particularly in the endemic region (severe vs. control, OR=14.56, 95% CI=3.39-85.81, P=3 × 10(-5)).	0.000271442	2014	NA	NA	NA	NA	NA
rs334	24312262	132014	IL17RE	umls:C0024530	BeFree	Furthermore, IL17RE rs708567 GA and hHbS rs334 AT individuals were associated with protection from uncomplicated malaria and anaemia respectively in this study.	0.000271442	2013	HBB	11	5227002	T	G,C,A
rs386502799	19602285	114609	TIRAP	umls:C0024530	BeFree	Low frequency of the TIRAP S180L polymorphism in Africa, and its potential role in malaria, sepsis, and leprosy.	0.120814326	2009	NA	NA	NA	NA	NA
rs386547285	21457584	54106	TLR9	umls:C0024530	BeFree	The tlr-4 (D299G and T399I), tlr-9 (T-1486C and T-1237C) and tirap (S180L) genes were assessed in 640 Baluchi individuals (320 Plasmodium falciparum-infected and 320 non-infected, median age of 28 years) from malaria-endemic regions using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) methods.	0.012539865	2011	NA	NA	NA	NA	NA
rs386547285	21457584	7099	TLR4	umls:C0024530	BeFree	The tlr-4 (D299G and T399I), tlr-9 (T-1486C and T-1237C) and tirap (S180L) genes were assessed in 640 Baluchi individuals (320 Plasmodium falciparum-infected and 320 non-infected, median age of 28 years) from malaria-endemic regions using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) methods.	0.015892975	2011	NA	NA	NA	NA	NA
rs3918242	26013370	4318	MMP9	umls:C0024530	BeFree	Matrix metalloproteinase-9 polymorphism 1562 C > T (rs3918242) associated with protection against placental malaria.	0.000542884	2015	MMP9	20	46007337	C	T
rs414171	20484391	1154	CISH	umls:C0024530	GAD	[When all five single-nucleotide polymorphisms (SNPs) (at positions -639, -292, -163, +1320, and +3415 all relative to CISH) within the CISH-associated locus were considered together in a multiple-SNP score, we found an association between CISH genetic variants and susceptibility to bacteremia, malaria, and tuberculosis (P=3.8x10(-11) for all comparisons), with -292 accounting for most of the association signal (P=4.58x10(-7)).]	0.122367032	2010	CISH;MAPKAPK3	3	50612068	A	T
rs4833095	20478407	7096	TLR1	umls:C0024530	BeFree	The toll-like receptor 1 variant S248N influences placental malaria.	0.002909916	2010	TLR1	4	38798089	T	C
rs4844600	25683978	1378	CR1	umls:C0024530	BeFree	These findings suggest that CR1 gene rs2274567 G/A, rs4844600 G/A, and rs2296160 C/T polymorphisms may not be involved in susceptibility to malaria in Chinese population.	0.124267125	2015	CR1	1	207505962	A	C,G
rs4986790	21457584	7099	TLR4	umls:C0024530	BeFree	The tlr-4 (D299G and T399I), tlr-9 (T-1486C and T-1237C) and tirap (S180L) genes were assessed in 640 Baluchi individuals (320 Plasmodium falciparum-infected and 320 non-infected, median age of 28 years) from malaria-endemic regions using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) methods.	0.015892975	2011	TLR4	9	117713024	A	G
rs4986790	21457584	54106	TLR9	umls:C0024530	BeFree	The tlr-4 (D299G and T399I), tlr-9 (T-1486C and T-1237C) and tirap (S180L) genes were assessed in 640 Baluchi individuals (320 Plasmodium falciparum-infected and 320 non-infected, median age of 28 years) from malaria-endemic regions using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) methods.	0.012539865	2011	TLR4	9	117713024	A	G
rs4986791	21457584	54106	TLR9	umls:C0024530	BeFree	The tlr-4 (D299G and T399I), tlr-9 (T-1486C and T-1237C) and tirap (S180L) genes were assessed in 640 Baluchi individuals (320 Plasmodium falciparum-infected and 320 non-infected, median age of 28 years) from malaria-endemic regions using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) methods.	0.012539865	2011	TLR4	9	117713324	C	T
rs4986791	21457584	7099	TLR4	umls:C0024530	BeFree	The tlr-4 (D299G and T399I), tlr-9 (T-1486C and T-1237C) and tirap (S180L) genes were assessed in 640 Baluchi individuals (320 Plasmodium falciparum-infected and 320 non-infected, median age of 28 years) from malaria-endemic regions using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) methods.	0.015892975	2011	TLR4	9	117713324	C	T
rs5030738	23935200	2209	FCGR1A	umls:C0024530	BeFree	Fc gamma receptor 3B (FCGR3B-c.233C>A-rs5030738) polymorphism modifies the protective effect of malaria specific antibodies in Ghanaian children.	0.001628651	2014	FCGR3B	1	161629864	G	T
rs5030738	23935200	2215	FCGR3B	umls:C0024530	BeFree	Fc gamma receptor 3B (FCGR3B-c.233C>A-rs5030738) polymorphism modifies the protective effect of malaria specific antibodies in Ghanaian children.	0.007915422	2014	FCGR3B	1	161629864	G	T
rs5498	19055786	3383	ICAM1	umls:C0024530	BeFree	Association of the ICAM1 rs5498 (exon 6) G allele and the CD36 exon 1a A allele with increased risk of severe malaria was observed (severe versus control, OR = 1.91 and 2.66, P = 0.02 and 0.0012, respectively).	0.134525834	2008	ICAM1;ICAM4;LOC105372272	19	10285007	A	G
rs5498	19055786	948	CD36	umls:C0024530	BeFree	Association of the ICAM1 rs5498 (exon 6) G allele and the CD36 exon 1a A allele with increased risk of severe malaria was observed (severe versus control, OR = 1.91 and 2.66, P = 0.02 and 0.0012, respectively).	0.133973019	2008	ICAM1;ICAM4;LOC105372272	19	10285007	A	G
rs5743836	21457584	54106	TLR9	umls:C0024530	BeFree	The tlr-4 (D299G and T399I), tlr-9 (T-1486C and T-1237C) and tirap (S180L) genes were assessed in 640 Baluchi individuals (320 Plasmodium falciparum-infected and 320 non-infected, median age of 28 years) from malaria-endemic regions using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) methods.	0.012539865	2011	TLR9	3	52226766	A	G
rs5743836	21457584	7099	TLR4	umls:C0024530	BeFree	The tlr-4 (D299G and T399I), tlr-9 (T-1486C and T-1237C) and tirap (S180L) genes were assessed in 640 Baluchi individuals (320 Plasmodium falciparum-infected and 320 non-infected, median age of 28 years) from malaria-endemic regions using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) methods.	0.015892975	2011	TLR9	3	52226766	A	G
rs6503319	19465909	4621	MYH3	umls:C0024530	GAD	[Genome-wide and fine-resolution association analysis of malaria in West Africa.]	0.002367032	2009	MYH3	17	10670842	C	T
rs6503319	19465909	6341	SCO1	umls:C0024530	GAD	[Genome-wide and fine-resolution association analysis of malaria in West Africa.]	0.002367032	2009	MYH3	17	10670842	C	T
rs668	19055786	5175	PECAM1	umls:C0024530	BeFree	Interestingly, a SNP of the PECAM1 gene (rs668, exon 3, C/G) with low minor allele frequency in populations of the endemic region compared to the non-endemic region exhibited differential association with disease in these regions; the G allele was a risk factor for malaria in the endemic region, but exhibited significant association with protection from disease in the non-endemic region.	0.003181358	2008	NA	NA	NA	NA	NA
rs6755404	23717212	91752	ZNF804A	umls:C0024530	GWASCAT	Imputation-based meta-analysis of severe malaria in three African populations.	0.12	2013	ZNF804A	2	184932501	A	C
rs708567	24312262	132014	IL17RE	umls:C0024530	BeFree	Furthermore, IL17RE rs708567 GA and hHbS rs334 AT individuals were associated with protection from uncomplicated malaria and anaemia respectively in this study.	0.000271442	2013	IL17RC	3	9918386	C	T
rs8078340	26448013	3552	IL1A	umls:C0024530	BeFree	A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324).	0.001085767	2016	NOS2	17	27802186	G	A
rs8078340	26448013	7124	TNF	umls:C0024530	BeFree	A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324).	0.157314477	2016	NOS2	17	27802186	G	A
rs8078340	26448013	959	CD40LG	umls:C0024530	BeFree	A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324).	0.004810009	2016	NOS2	17	27802186	G	A
rs8078340	26448013	3565	IL4	umls:C0024530	BeFree	A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324).	0.009977336	2016	NOS2	17	27802186	G	A
rs8078340	26448013	4843	NOS2	umls:C0024530	BeFree	A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324).	0.139445464	2016	NOS2	17	27802186	G	A
rs8078340	26448013	55692	LUC7L	umls:C0024530	BeFree	A GTGTGTC haplotype consisting of IL-1A (rs17561), IL-4 (rs2243250), TNF (rs1800750), IL-4R (rs1805015), NOS (rs8078340), CD40LG (rs1126535), and LUC7L (rs1211375) was significantly associated with the prevalence of malaria (POR: 1.822, 95% CI: 0.998-3.324).	0.000271442	2016	NOS2	17	27802186	G	A
rs8176719	22895189	28	ABO	umls:C0024530	GWASCAT	Genome-wide association study indicates two novel resistance loci for severe malaria.	0.130358398	2012	NA	9	133257521	-	C
rs8176722	23717212	28	ABO	umls:C0024530	GWASCAT	Imputation-based meta-analysis of severe malaria in three African populations.	0.130358398	2013	ABO	9	133257367	C	A
rs8177374	19602285	114609	TIRAP	umls:C0024530	BeFree	Low frequency of the TIRAP S180L polymorphism in Africa, and its potential role in malaria, sepsis, and leprosy.	0.120814326	2009	TIRAP	11	126292948	C	T
rs9429942	18954261	1378	CR1	umls:C0024530	BeFree	The T allele of the reference single-nucleotide polymorphism rs9429942 in the CR1 promoter region was strongly associated with protection against cerebral malaria (2.2% of patients with mild malaria vs. 7.8% of patients with cerebral malaria; P = .0009; Bonferroni-adjusted Pc = .0306.	0.124267125	2008	CR1	1	207495285	C	T
rs9658676	21625619	2194	FASN	umls:C0024530	BeFree	We found the A allele of c.-436C>A (rs9658676) located in the promoter region of FAS to be significantly associated with protection from severe childhood malaria (odds ratio 0.71, 95% confidence interval 0.58-0.88, p(empirical) = 0.02) and confirmed this finding in a replication group of 1,412 additional severe malaria cases and 2,659 community controls from the same geographic area.	0.000542884	2011	ACTA2;FAS	10	88990441	C	A
rs9940464	23717212	1012	CDH13	umls:C0024530	GWASCAT	Imputation-based meta-analysis of severe malaria in three African populations.	0.12	2013	CDH13	16	83327170	T	C

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:179)
CHR	POS	SNPID	REF	ALT	ORI_SNPID	PMID	P_VALUE	P_VALUE_TEXT	OR/BETA	CI95_TEXT	GWAS_INITIAL_SAMPLE_SIZE	SUB_POPULATION	SUPER_POPULATION	GWAS_TRAIT	HPO_ID	HPO_TERM	DO_ID	DO_TERM	MESH_ID	MESH_TERM	EFO_ID	EFO_TERM	DOLITE_TERM	RISK_ALLELE	PUBLICATION_TYPE	AA	GENE_SYMBOL	TYPE	REFGENE
1	6829582	rs448886	C	A	rs448886	19465909	2.50E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
1	26475521	rs868551	A	G	rs868551	19465909	6.90E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
1	30923203	rs454774	G	T	rs454774	19465909	2.10E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
1	42026023	rs10789394	G	A	rs10789394	19465909	8.10E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
1	46321843	rs6429582	T	C	rs6429582	19465909	6.00E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
1	46346234	rs10890361	T	A	rs10890361	19465909	9.40E-06	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
1	46356148	rs10890363	A	G	rs10890363	19465909	9.10E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
1	46363880	rs7556436	A	G	rs7556436	19465909	5.20E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
1	69520596	rs1507860	G	A	rs1507860	19465909	4.80E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
1	73245168	rs10889990	G	A	rs10889990	19465909	5.10E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
1	73245256	rs10889991	G	A	rs10889991	19465909	7.70E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
1	76435420	rs12405994	A	T	rs12405994	19465909	3.80E-07	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
1	76437196	rs1417402	G	A	rs1417402	19465909	5.00E-07	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
1	80538189	rs1414411	T	C	rs1414411	19465909	5.20E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
1	95554294	rs7512953	T	G	rs7512953	19465909	2.30E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
1	152780139	rs7411365	C	T	rs7411365	19465909	1.80E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
1	168560132	rs7556321	G	A	rs7556321	19465909	3.80E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
1	169712597	rs10489181	T	C	rs10489181	19465909	7.70E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
1	192763948	rs10801153	G	A	rs10801153	19465909	2.10E-06	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
1	203654024	rs10900585	G	T	rs10900585	22895189	2.00E-10	NA	1.64	NA	1,325 African ancestry; 828 African ancestry controls	African(2153)	ALL(2153)	AFR(2153)	ALL(2153)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
1	203660781	rs4951074	A	G	rs4951074	22895189	1.80E-08	NA	NA	NA	1,325 African ancestry; 828 African ancestry controls	African(2153)	ALL(2153)	AFR(2153)	ALL(2153)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
1	204283624	rs4245727	C	G	rs4245727	19465909	1.40E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
1	237605491	rs12087410	C	G	rs12087410	19465909	7.80E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
2	66792109	rs12614369	A	G	rs12614369	19465909	3.60E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
2	77494953	rs7563141	G	T	rs7563141	19465909	7.20E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
2	107243678	rs13025573	G	A	rs13025573	19465909	2.90E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
2	138732281	rs3113205	C	G	rs3113205	19465909	3.80E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
2	185766912	rs7590852	T	C	rs7590852	23717212	4.16E-06	NA	1.17	[1.09-1.25]	5,425 African cases; 6,891 African controls	African(12316)	ALL(12316)	AFR(12316)	ALL(12316)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
2	185778262	rs725617	G	A	rs725617	23717212	4.60E-06	NA	1.17	[1.09-1.25]	5,425 African cases; 6,891 African controls	African(12316)	ALL(12316)	AFR(12316)	ALL(12316)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
2	185797228	rs6755404	A	C	rs6755404	23717212	1.00E-06	NA	1.26	[1.15-1.38]	5,425 African cases; 6,891 African controls	African(12316)	ALL(12316)	AFR(12316)	ALL(12316)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
2	231877319	rs2136477	G	A	rs2136477	19465909	5.20E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
2	231878496	rs1543061	C	T	rs1543061	19465909	9.60E-07	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
2	231878740	rs10192428	G	A	rs10192428	19465909	5.10E-07	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
2	231880112	rs6750230	G	A	rs6750230	19465909	1.60E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
2	231880308	rs6750277	C	T	rs6750277	19465909	6.60E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
2	233067832	rs4973508	T	A	rs4973508	19465909	1.00E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
3	36516326	rs1350146	G	A	rs1350146	19465909	4.30E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
3	43132444	rs488069	C	T	rs488069	19465909	7.60E-07	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
3	73869793	rs9848344	G	A	rs9848344	19465909	8.00E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
3	119504140	rs11712211	T	C	rs11712211	19465909	6.80E-06	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
3	135282024	rs9833932	C	T	rs9833932	19465909	4.70E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
3	184875106	rs6797705	G	C	rs6797705	19465909	3.20E-06	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
4	5527249	rs2267654	A	G	rs2267654	19465909	8.50E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
4	26503983	rs2046784	G	A	rs2046784	19465909	2.50E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
4	26504157	rs2130250	G	T	rs2130250	19465909	3.80E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
4	107305565	rs2949632	G	A	rs2949632	19465909	6.50E-06	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
4	107310444	rs2949641	A	G	rs2949641	19465909	1.30E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
4	160684694	rs4690956	A	G	rs4690956	19465909	3.80E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
5	1300025	rs2853668	G	T	rs2853668	19465909	2.20E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
5	43004280	rs316414	A	G	rs316414	19465909	4.50E-07	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
5	43016650	rs222060	C	T	rs222060	19465909	7.40E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
5	43094029	rs316413	T	C	rs316413	19465909	7.90E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
5	79100717	rs259065	A	G	rs259065	19465909	9.40E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
5	90725887	rs4432929	C	T	rs4432929	19465909	1.30E-04	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
5	104335746	rs2403256	A	T	rs2403256	19465909	5.00E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
5	113227270	rs4449520	G	C	rs4449520	19465909	4.90E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
5	131370712	rs10074987	G	A	rs10074987	19465909	7.00E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
5	142289541	rs830532	C	T	rs830532	20657648	3.70E-05	P. falciparum infection intensity and mild malaria attack (Intensity of plasmodial infection)	NA	NA	626 African ancestry samples	African(626)	ALL(626)	AFR(626)	ALL(626)	Malarial infection	HPOID:0002718	Recurrent bacterial infections	DOID:12365	malaria	NA	NA	NA	NA	Malaria	NA	Research Support, Non-U.S. Gov't	A	ARHGAP26
5	149014418	rs1056189	A	G	rs1056189	20657648	8.50E-04	P. falciparum infection intensity and mild malaria attack (Mean level of P. falciparum density)	NA	NA	626 African ancestry samples	African(626)	ALL(626)	AFR(626)	ALL(626)	Malarial infection	HPOID:0002718	Recurrent bacterial infections	DOID:12365	malaria	NA	NA	NA	NA	Malaria	NA	Research Support, Non-U.S. Gov't	A	ARHGEF37
6	64058565	rs1741797	T	C	rs1741797	19465909	5.20E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
6	68475531	rs4541731	T	C	rs4541731	19465909	5.20E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
6	81332877	rs2444796	A	G	rs2444796	19465909	7.20E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
6	87739154	rs17822183	C	T	rs17822183	19465909	3.90E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
6	106207093	rs6568402	A	G	rs6568402	19465909	8.60E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
6	141096809	rs647706	A	T	rs647706	19465909	6.90E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
6	151228071	rs712209	T	C	rs712209	19465909	1.10E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
6	162344712	rs9458419	C	T	rs9458419	19465909	1.40E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
7	45250348	rs1294878	T	C	rs1294878	19465909	8.20E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
7	50622712	rs1451375	C	A	rs1451375	19465909	6.00E-06	NA	1.33	[1.18-1.52]	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
7	50623451	rs10249420	C	G	rs10249420	19465909	6.80E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
7	50625898	rs7803788	C	T	rs7803788	19465909	7.90E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
7	132064886	rs10269601	C	A	rs10269601	19465909	1.10E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
7	132069727	rs4731867	T	G	rs4731867	19465909	9.00E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
7	153399165	rs1558301	A	G	rs1558301	19465909	5.80E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
8	13557493	rs2410094	C	T	rs2410094	19465909	6.00E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
8	13560003	rs1384057	G	A	rs1384057	19465909	2.40E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
8	58789168	rs10504248	T	C	rs10504248	19465909	7.80E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
8	91440226	rs2205156	T	C	rs2205156	19465909	5.70E-06	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
8	103574663	rs2436893	G	A	rs2436893	19465909	5.10E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
8	120941528	rs4871793	C	T	rs4871793	19465909	1.10E-04	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
8	128204216	rs1473581	C	T	rs1473581	19465909	4.50E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
9	107457275	rs10820709	A	C	rs10820709	19465909	5.90E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
9	132008768	rs7023548	C	T	rs7023548	23717212	1.34E-07	NA	1.28	[1.17-1.40]	5,425 African cases; 6,891 African controls	African(12316)	ALL(12316)	AFR(12316)	ALL(12316)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
9	136121303	rs7855466	C	T	rs7855466	23717212	5.51E-07	NA	1.16	[1.10-1.24]	5,425 African cases; 6,891 African controls	African(12316)	ALL(12316)	AFR(12316)	ALL(12316)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
9	136131022	rs8176751	C	T	rs8176751	23717212	1.06E-09	NA	1.26	[1.17-1.36]	5,425 African cases; 6,891 African controls	African(12316)	ALL(12316)	AFR(12316)	ALL(12316)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
9	136131188	rs8176749	C	T	rs8176749	23717212	1.20E-07	NA	1.23	[1.14-1.33]	5,425 African cases; 6,891 African controls	African(12316)	ALL(12316)	AFR(12316)	ALL(12316)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
9	136131322	rs8176746	G	T	rs8176746	23717212	1.14E-07	NA	1.23	[1.14-1.33]	5,425 African cases; 6,891 African controls	African(12316)	ALL(12316)	AFR(12316)	ALL(12316)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
9	136131415	rs8176743	C	T	rs8176743	23717212	8.29E-08	NA	1.23	[1.14-1.33]	5,425 African cases; 6,891 African controls	African(12316)	ALL(12316)	AFR(12316)	ALL(12316)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
9	136132754	rs8176722	C	A	rs8176722	23717212	9.00E-10	NA	1.28	[1.19-1.39]	5,425 African cases; 6,891 African controls	African(12316)	ALL(12316)	AFR(12316)	ALL(12316)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
9	136132908	rs77641731	T	C	rs8176719	22895189	4.00E-21	NA	1.48	NA	1,325 African ancestry; 828 African ancestry controls	African(2153)	ALL(2153)	AFR(2153)	ALL(2153)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
9	136132908	rs8176719	T	TC	rs8176719	22895189	4.00E-21	NA	1.48	NA	1,325 African ancestry; 828 African ancestry controls	African(2153)	ALL(2153)	AFR(2153)	ALL(2153)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
9	136135863	rs8176703	G	T	rs8176703	22895189	2.10E-12	NA	NA	NA	1,325 African ancestry; 828 African ancestry controls	African(2153)	ALL(2153)	AFR(2153)	ALL(2153)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
9	136137657	rs8176693	C	T	rs8176693	23717212	3.73E-08	NA	1.26	[1.16-1.36]	5,425 African cases; 6,891 African controls	African(12316)	ALL(12316)	AFR(12316)	ALL(12316)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
9	136142185	rs8176672	C	T	rs8176672	23717212	4.85E-08	NA	1.26	[1.16-1.37]	5,425 African cases; 6,891 African controls	African(12316)	ALL(12316)	AFR(12316)	ALL(12316)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
9	136149229	rs505922	T	C	rs505922	23717212	2.32E-08	NA	1.18	[1.11-1.25]	5,425 African cases; 6,891 African controls	African(12316)	ALL(12316)	AFR(12316)	ALL(12316)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
10	4564553	rs1904667	A	G	rs1904667	19465909	1.00E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
10	5652237	rs7924096	G	C	rs7924096	19465909	4.40E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
10	23094828	rs946961	G	C	rs946961	19465909	6.90E-06	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
10	23098092	rs11013140	T	C	rs11013140	19465909	5.60E-06	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
10	69547057	rs4746711	A	G	rs4746711	19465909	9.20E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
10	101104712	rs10786538	G	A	rs10786538	19465909	2.50E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
10	101105002	rs11190062	A	G	rs11190062	19465909	1.30E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
10	126338444	rs7076268	C	T	rs7076268	19465909	1.60E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
10	126399566	rs4962686	T	C	rs4962686	19465909	7.30E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
10	128213658	rs1370108	C	T	rs1370108	19465909	1.50E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
11	4592277	rs1505209	A	G	rs1505209	23717212	2.01E-08	NA	1.62	[1.37-1.91]	5,425 African cases; 6,891 African controls	African(12316)	ALL(12316)	AFR(12316)	ALL(12316)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
11	4715946	rs7105156	A	G	rs7105156	19465909	7.10E-06	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
11	4790575	rs12788102	A	G	rs12788102	23717212	2.00E-16	NA	2.15	[1.79-2.59]	5,425 African cases; 6,891 African controls	African(12316)	ALL(12316)	AFR(12316)	ALL(12316)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
11	4794119	rs12789492	C	T	rs12789492	23717212	3.89E-16	NA	2.11	[1.76-2.52]	5,425 African cases; 6,891 African controls	African(12316)	ALL(12316)	AFR(12316)	ALL(12316)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
11	4799209	rs1594812	T	G	rs1594812	23717212	1.32E-15	NA	2.09	[1.74-2.50]	5,425 African cases; 6,891 African controls	African(12316)	ALL(12316)	AFR(12316)	ALL(12316)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
11	4806872	rs12806476	T	G	rs12806476	23717212	4.40E-16	NA	2.1	[1.76-2.51]	5,425 African cases; 6,891 African controls	African(12316)	ALL(12316)	AFR(12316)	ALL(12316)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
11	4807054	rs12801757	A	G	rs12801757	23717212	2.11E-15	NA	2.06	[1.73-2.47]	5,425 African cases; 6,891 African controls	African(12316)	ALL(12316)	AFR(12316)	ALL(12316)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
11	4807972	rs12808215	A	G	rs12808215	23717212	9.20E-15	NA	2.01	[1.69-2.40]	5,425 African cases; 6,891 African controls	African(12316)	ALL(12316)	AFR(12316)	ALL(12316)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
11	4808133	rs17325567	T	C	rs17325567	23717212	4.06E-16	NA	2.1	[1.75-2.50]	5,425 African cases; 6,891 African controls	African(12316)	ALL(12316)	AFR(12316)	ALL(12316)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
11	4808425	rs17227978	G	A	rs17227978	23717212	4.26E-16	NA	2.09	[1.75-2.50]	5,425 African cases; 6,891 African controls	African(12316)	ALL(12316)	AFR(12316)	ALL(12316)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
11	4810364	rs17228092	T	C	rs17228092	23717212	4.51E-16	NA	2.1	[1.76-2.51]	5,425 African cases; 6,891 African controls	African(12316)	ALL(12316)	AFR(12316)	ALL(12316)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
11	4811800	rs17228176	A	G	rs17228176	23717212	7.03E-16	NA	2.09	[1.75-2.50]	5,425 African cases; 6,891 African controls	African(12316)	ALL(12316)	AFR(12316)	ALL(12316)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
11	4811883	rs17228183	G	A	rs17228183	23717212	7.05E-16	NA	2.09	[1.75-2.50]	5,425 African cases; 6,891 African controls	African(12316)	ALL(12316)	AFR(12316)	ALL(12316)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
11	5019985	rs16908208	T	C	rs16908208	19465909	1.40E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
11	5060941	rs2034839	G	A	rs2034839	19465909	4.30E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
11	5061541	rs2499984	A	G	rs2499984	19465909	7.70E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
11	5067358	rs2500012	C	T	rs2500012	19465909	4.40E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
11	5067389	rs2500013	G	T	rs2500013	19465909	8.30E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
11	5072835	rs2959184	C	T	rs2959184	19465909	2.90E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
11	5096331	rs4144715	A	G	rs4144715	23717212	6.07E-06	NA	1.14	[1.08-1.21]	5,425 African cases; 6,891 African controls	African(12316)	ALL(12316)	AFR(12316)	ALL(12316)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
11	5225635	rs11036238	G	C	rs11036238	19465909	4.00E-11	NA	1.59	[1.39-1.82]	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
11	5248232	rs281864519	TCA	T	rs334	19465909	1.30E-28	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
11	5248232	rs281864519	TCA	T	rs334	22895189	1.40E-38	NA	NA	NA	1,325 African ancestry; 828 African ancestry controls	African(2153)	ALL(2153)	AFR(2153)	ALL(2153)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
11	5248232	rs334	T	A,C,G	rs334	19465909	1.30E-28	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
11	5248232	rs334	T	A,C,G	rs334	22895189	1.40E-38	NA	NA	NA	1,325 African ancestry; 828 African ancestry controls	African(2153)	ALL(2153)	AFR(2153)	ALL(2153)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
11	5308896	rs11036635	G	A	rs11036635	19465909	4.80E-06	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
11	5372690	rs4373970	A	G	rs4373970	19465909	6.70E-06	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
11	5406123	rs4910780	T	C	rs4910780	19465909	2.30E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
11	5442226	rs17359438	T	C	rs17359438	19465909	1.10E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
11	5463425	rs16931041	T	C	rs16931041	19465909	1.10E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
11	5518156	rs372091	A	G	rs372091	22895189	6.00E-14	NA	2.17	NA	1,325 African ancestry; 828 African ancestry controls	African(2153)	ALL(2153)	AFR(2153)	ALL(2153)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
11	5545822	rs2010794	A	T	rs2010794	19465909	4.80E-06	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
11	11766709	rs11022014	T	C	rs11022014	19465909	4.90E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
11	19297062	rs11025082	G	A	rs11025082	19465909	5.10E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
11	93691008	rs1518555	A	C	rs1518555	19465909	2.70E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
11	95953493	rs16923343	G	A	rs16923343	19465909	2.80E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
11	110739555	rs11213630	A	G	rs11213630	23717212	3.03E-07	NA	1.19	[1.12-1.28]	5,425 African cases; 6,891 African controls	African(12316)	ALL(12316)	AFR(12316)	ALL(12316)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
11	110741014	rs1469170	A	G	rs1469170	23717212	8.00E-08	NA	1.2	[1.12-1.29]	5,425 African cases; 6,891 African controls	African(12316)	ALL(12316)	AFR(12316)	ALL(12316)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
11	132911101	rs11223336	A	G	rs11223336	19465909	8.30E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
12	104902190	rs2141857	C	A	rs2141857	19465909	6.60E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
13	23346768	rs4770301	T	C	rs4770301	19465909	3.30E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
13	36615408	rs1750719	G	T	rs1750719	19465909	9.30E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
13	39779861	rs7330452	A	C	rs7330452	19465909	8.60E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
13	54296049	rs2806735	A	G	rs2806735	19465909	9.10E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
13	93699203	rs1444227	G	C	rs1444227	19465909	3.60E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
13	93712869	rs1158878	G	A	rs1158878	19465909	4.20E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
14	36854136	rs12590640	C	T	rs12590640	23717212	4.00E-06	NA	1.15	[1.09-1.23]	5,425 African cases; 6,891 African controls	African(12316)	ALL(12316)	AFR(12316)	ALL(12316)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
14	46366562	rs17726637	C	T	rs17726637	19465909	1.20E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
14	46434585	rs6572335	A	G	rs6572335	19465909	9.30E-07	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
14	46467831	rs17728971	A	G	rs17728971	19465909	6.50E-07	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
14	81853407	rs1569012	C	T	rs1569012	19465909	2.80E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
15	27773791	rs3097490	G	A	rs3097490	19465909	6.70E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
15	31234064	rs6493352	C	T	rs6493352	19465909	3.60E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
15	53545261	rs492391	G	A	rs492391	19465909	2.00E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
16	57468408	rs16957051	T	C	rs16957051	19465909	2.50E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
16	57503330	rs2161647	C	A	rs2161647	19465909	4.10E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
16	71653637	rs2334880	A	G	rs2334880	22895189	2.00E-06	NA	1.19	NA	1,325 African ancestry; 828 African ancestry controls	African(2153)	ALL(2153)	AFR(2153)	ALL(2153)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
16	78926616	rs11647676	T	A	rs11647676	19465909	9.30E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
16	78930216	rs2292124	G	C	rs2292124	19465909	3.10E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
16	83348824	rs1035569	A	G	rs1035569	23717212	2.20E-06	NA	1.17	[1.09-1.24]	5,425 African cases; 6,891 African controls	African(12316)	ALL(12316)	AFR(12316)	ALL(12316)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
16	83349398	rs7194029	T	C	rs7194029	23717212	3.67E-06	NA	1.16	[1.09-1.24]	5,425 African cases; 6,891 African controls	African(12316)	ALL(12316)	AFR(12316)	ALL(12316)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
16	83360775	rs9940464	T	C	rs9940464	23717212	5.00E-07	NA	1.17	[1.10-1.25]	5,425 African cases; 6,891 African controls	African(12316)	ALL(12316)	AFR(12316)	ALL(12316)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
16	83368400	rs10514577	G	C	rs10514577	23717212	1.06E-06	NA	1.17	[1.10-1.24]	5,425 African cases; 6,891 African controls	African(12316)	ALL(12316)	AFR(12316)	ALL(12316)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
17	10574159	rs6503319	C	T	rs6503319	19465909	7.00E-07	NA	1.21	[1.12-1.31]	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
18	24250211	rs12960395	G	A	rs12960395	19465909	5.80E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
19	6941161	rs460375	G	C	rs460375	19465909	1.20E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
19	6941867	rs465543	G	A	rs465543	19465909	6.10E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
19	41804976	rs11879562	G	C	rs11879562	19465909	5.00E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
19	58648359	rs159667	C	T	rs159667	19465909	7.80E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
20	19348676	rs6112327	A	T	rs6112327	19465909	1.00E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
20	51923969	rs6512879	T	G	rs6512879	19465909	4.30E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
21	16790213	rs2823263	T	C	rs2823263	19465909	1.80E-06	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
22	35242350	rs7286095	G	A	rs7286095	19465909	4.60E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache
22	38753956	rs6001102	C	G	rs6001102	19465909	8.40E-05	NA	NA	NA	958 African ancestry cases; 1,382 African ancestry controls; all children	African(2340)	ALL(2340)	AFR(2340)	ALL(2340)	Malaria	HPOID:0004386	HPOID:0002315	HPOID:0001945	HPOID:0002829	HPOID:0002013	HPOID:0002018	HPOID:0001878	HPOID:0000952	HPOID:0003641	HPOID:0000480	HPOID:0001279	Gastrointestinal inflammation	Headache

Mapped by lexical matching(Total Items:6)
HP ID	HP Name	MP ID	MP Name	Annotation
HP:0002011	Morphological abnormality of the central nervous system	MP:0009886	failure of palatal shelf elevation	the palatal shelves fail to move from a vertical position in the orofacial cavity to a horizontal apposition above the developing tongue
HP:0002098	Respiratory distress	MP:0001954	respiratory distress	physical difficulty or inability to breathe; shortness of breath
HP:0001871	Abnormality of blood and blood-forming tissues	MP:0004686	decreased length of long bones	reduced end-to-end length of the several elongated bones of the extremities
HP:0001919	Acute kidney injury	MP:0011423	kidney cortex atrophy	acquired diminution of the size of the outer portion of the kidney located between the renal capsule and the renal medulla, associated with wasting as from death and reabsorbtion of cells, diminished cellular proliferation, decreased cellular volume, pres
HP:0002017	Nausea and vomiting	MP:0010426	abnormal heart and great artery attachment	any anomaly in the in the position or pattern of the connection site of the heart to any of the great arteries, including the pulmonary artery and aorta
HP:0011227	Elevated C-reactive protein level	MP:0008721	abnormal chemokine level	deviation from the normal levels of any of the class of pro-inflammatory cytokines that attract and activate leukocytes

Mapped by homologous gene(Total Items:16)
HP ID	HP Name	MP ID	MP Name	Annotation
HP:0000488	Retinopathy	MP:0020137	decreased bone mineralization	decrease in the rate at which minerals are deposited into bone
HP:0100543	Cognitive impairment	MP:0020316	decreased vascular endothelial cell proliferation	decrease in the expansion rate of any vascular endothelial cell population by cell division
HP:0002904	Hyperbilirubinemia	MP:0020137	decreased bone mineralization	decrease in the rate at which minerals are deposited into bone
HP:0002141	Gait imbalance	MP:0013279	increased fasted circulating glucose level	increase in the amount of glucose in the blood at some defined time point after eating compared to controls
HP:0001945	Fever	MP:0020254	decreased collagen level	decreased level of the main structural protein of the various connective tissues in animals
HP:0002315	Headache	MP:0020137	decreased bone mineralization	decrease in the rate at which minerals are deposited into bone
HP:0002098	Respiratory distress	MP:0014198	absent pituitary infundibular stalk	absence of the apical portion of the tubular structure extending from the hypothalamus to the posterior lobe of the pituitary gland
HP:0001919	Acute kidney injury	MP:0020216	decreased circulating complement protein level	less than normal levels of the serum proteins that act sequentially to allow for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes
HP:0004372	Reduced consciousness/confusion	MP:0013405	increased circulating lactate level	greater amount of lactate in the blood which is produced from pyruvate by lactate dehydrogenase
HP:0002011	Morphological abnormality of the central nervous system	MP:0014185	cerebellum atrophy	acquired diminution of the size of the cerebellum associated with wasting as from death and reabsorption of cells, diminished cellular proliferation, decreased cellular volume, pressure, ischemia, malnutrition, reduced function or malfunction, or hormonal
HP:0001873	Thrombocytopenia	MP:0020329	decreased capillary density	reduction in the number of capillaries in a given cross-sectional area of a tissue
HP:0003326	Myalgia	MP:0020309	increased creatine kinase activity	increased ability of to catalyze the reaction: ATP + creatine = N-phosphocreatine + ADP + 2 H(+).
HP:0001871	Abnormality of blood and blood-forming tissues	MP:0013367	parotid gland inflammation	local accumulation of fluid, plasma proteins, and leukocytes in either of the largest of the major salivary glands situated below and in front of each ear
HP:0001903	Anemia	MP:0020316	decreased vascular endothelial cell proliferation	decrease in the expansion rate of any vascular endothelial cell population by cell division
HP:0002017	Nausea and vomiting	MP:0020220	decreased tear production	decreased production of the amount of fluid produced in the eye
HP:0011227	Elevated C-reactive protein level	MP:0008721	abnormal chemokine level	deviation from the normal levels of any of the class of pro-inflammatory cytokines that attract and activate leukocytes

Disease ID	180
Disease	malaria
Case	(Waiting for update.)