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	hypokalemia

Disease ID	1507
Disease	hypokalemia
Definition	Abnormally low potassium concentration in the blood. It may result from potassium loss by renal secretion or by the gastrointestinal route, as by vomiting or diarrhea. It may be manifested clinically by neuromuscular disorders ranging from weakness to paralysis, by electrocardiographic abnormalities (depression of the T wave and elevation of the U wave), by renal disease, and by gastrointestinal disorders. (Dorland, 27th ed)
Synonym	deficiency k deficiency potassium hypokalaemia hypokalaemia (disorder) hypokalaemic syndrome hypokalemia (disorder) hypokalemia [disease/finding] hypokalemias hypokalemic syndrome hypopotassaemia hypopotassaemia syndrome hypopotassemia hypopotassemia syndrome hypopotassemias k deficiency low blood potassium levels low potassium syndrome low serum potassium level low serum potassium level (finding) low serum potassium level - finding potassium deficiency potassium depletion syndrome hypokalemic
DOID	DOID:4500 DOID:13582
ICD10	ICD10CM:E87.6
UMLS	C0020621
MeSH	D007008 D011191
SNOMED-CT	SNOMEDCT_US_2016_09_01:43339004
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:87) C0020538 \| hypertension \| 18 C0011991 \| diarrhea \| 6 C0001126 \| renal tubular acidosis \| 6 C0020428 \| aldosteronism \| 5 C0024523 \| malabsorption \| 4 C0268450 \| gitelman's syndrome \| 4 C0004775 \| bartter syndrome \| 4 C1384514 \| primary aldosteronism \| 4 C0020456 \| hyperglycemia \| 3 C0018801 \| heart failure \| 3 C0020428 \| hyperaldosteronism \| 3 C0030443 \| periodic paralysis \| 3 C0011880 \| diabetic ketoacidosis \| 3 C0162429 \| malnutrition \| 3 C0268450 \| gitelman syndrome \| 2 C0007222 \| cardiovascular disease \| 2 C0003125 \| anorexia nervosa \| 2 C0042373 \| vascular disease \| 2 C0036992 \| short bowel syndrome \| 2 C0011860 \| type 2 diabetes \| 2 C0040156 \| thyrotoxicosis \| 2 C1527336 \| sjogren's syndrome \| 2 C0024523 \| intestinal malabsorption \| 2 C0745140 \| hyperthyroid \| 2 C0019151 \| hepatic encephalopathy \| 2 C0035078 \| renal failure \| 2 C0155616 \| secondary hypertension \| 2 C1565489 \| renal insufficiency \| 1 C0014038 \| encephalitis \| 1 C0013473 \| eating disorder \| 1 C0022681 \| sponge kidney \| 1 C0033687 \| proteinuria \| 1 C0004775 \| bartter's syndrome \| 1 C0020550 \| hyperthyroidism \| 1 C0011847 \| diabetes \| 1 C0242363 \| pancreatic endocrine tumor \| 1 C0029456 \| osteoporosis \| 1 C0037274 \| dermatoses \| 1 C0040100 \| thymoma \| 1 C0238402 \| pycnodysostosis \| 1 C0010481 \| cushing syndrome \| 1 C0037998 \| splenic infarction \| 1 C0013395 \| indigestion \| 1 C0019202 \| wilson's disease \| 1 C0001430 \| adenoma \| 1 C0015974 \| periodic fever \| 1 C0017160 \| gastroenteritis \| 1 C0022660 \| acute renal failure \| 1 C0022658 \| kidney disease \| 1 C0022658 \| renal disease \| 1 C1384514 \| conn's syndrome \| 1 C0221043 \| pseudohyperaldosteronism \| 1 C0004096 \| asthma \| 1 C0018799 \| heart disease \| 1 C0021400 \| influenza \| 1 C0009377 \| colonic pseudo-obstruction \| 1 C0013473 \| eating disorders \| 1 C0022681 \| medullary sponge kidney \| 1 C0162429 \| undernutrition \| 1 C0001623 \| adrenal insufficiency \| 1 C0018799 \| heart diseases \| 1 C0011860 \| type 2 diabetes mellitus \| 1 C0023895 \| liver disease \| 1 C0020540 \| malignant hypertension \| 1 C0022661 \| end-stage kidney disease \| 1 C0238358 \| hypokalemic periodic paralysis \| 1 C0020502 \| hyperparathyroidism \| 1 C0334684 \| renal adenoma \| 1 C0206686 \| adrenocortical carcinoma \| 1 C0011570 \| depression \| 1 C1621895 \| adrenal hyperplasia \| 1 C0264716 \| chronic heart failure \| 1 C0020450 \| hyperemesis gravidarum \| 1 C0010481 \| cushing's syndrome \| 1 C0342494 \| adrenal cortical hyperplasia \| 1 C0020437 \| hypercalcemia \| 1 C0018802 \| congestive heart failure \| 1 C0020456 \| hyperglycaemia \| 1 C0011991 \| diarrhoea \| 1 C0948265 \| metabolic syndrome \| 1 C0020598 \| hypoglycemia \| 1 C0235250 \| hyperemesis \| 1 C0206667 \| adrenal adenoma \| 1 C0010674 \| cystic fibrosis \| 1 C0021831 \| bowel disease \| 1 C0002871 \| anemia \| 1 C0021390 \| inflammatory bowel disease \| 1
Curated Gene	Entrez_id \| Symbol \| Resource(Total Genes:7) 3630 \| INS \| CTD_human 5443 \| POMC \| CTD_human 183 \| AGT \| CTD_human 4879 \| NPPB \| CTD_human 6750 \| SST \| CTD_human 154 \| ADRB2 \| CTD_human 2908 \| NR3C1 \| CTD_human
Inferring Gene	(Waiting for update.)
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:74) 270 \| AMPD1 \| 1.612 \| DISEASES 27063 \| ANKRD1 \| 1.074 \| DISEASES 480 \| ATP1A4 \| 1.606 \| DISEASES 481 \| ATP1B1 \| 1.339 \| DISEASES 551 \| AVP \| 3.711 \| DISEASES 554 \| AVPR2 \| 1.008 \| DISEASES 567 \| B2M \| 2.389 \| DISEASES 7809 \| BSND \| 4.08 \| DISEASES 779 \| CACNA1S \| 4.258 \| DISEASES 796 \| CALCA \| 2.395 \| DISEASES 797 \| CALCB \| 1.352 \| DISEASES 846 \| CASR \| 2.171 \| DISEASES 1041 \| CDSN \| 1.8 \| DISEASES 1184 \| CLCN5 \| 2.312 \| DISEASES 1187 \| CLCNKA \| 1.337 \| DISEASES 1188 \| CLCNKB \| 5.42 \| DISEASES 56259 \| CTNNBL1 \| 2.269 \| DISEASES 1528 \| CYB5A \| 1.866 \| DISEASES 1585 \| CYP11B2 \| 4.396 \| DISEASES 1586 \| CYP17A1 \| 4.932 \| DISEASES 1589 \| CYP21A2 \| 1.116 \| DISEASES 1576 \| CYP3A4 \| 1.541 \| DISEASES 57222 \| ERGIC1 \| 2.314 \| DISEASES 2556 \| GABRA3 \| 1.344 \| DISEASES 2520 \| GAST \| 2.469 \| DISEASES 2641 \| GCG \| 2.416 \| DISEASES 2695 \| GIP \| 1.324 \| DISEASES 23426 \| GRIP1 \| 2.109 \| DISEASES 8971 \| H1FX \| 1.612 \| DISEASES 3283 \| HSD3B1 \| 1.172 \| DISEASES 3284 \| HSD3B2 \| 1.581 \| DISEASES 54617 \| INO80 \| 1.498 \| DISEASES 102723508 \| KANTR \| 2.285 \| DISEASES 3753 \| KCNE1 \| 3.37 \| DISEASES 3758 \| KCNJ1 \| 5.246 \| DISEASES 3766 \| KCNJ10 \| 3.114 \| DISEASES 3768 \| KCNJ12 \| 2.283 \| DISEASES 3770 \| KCNJ14 \| 2.026 \| DISEASES 3772 \| KCNJ15 \| 1.714 \| DISEASES 3762 \| KCNJ5 \| 3.349 \| DISEASES 3775 \| KCNK1 \| 2.902 \| DISEASES 8645 \| KCNK5 \| 1.214 \| DISEASES 3778 \| KCNMA1 \| 2.761 \| DISEASES 56479 \| KCNQ5 \| 1.01 \| DISEASES 9622 \| KLK4 \| 2.162 \| DISEASES 4151 \| MB \| 2.42 \| DISEASES 4221 \| MEN1 \| 1.145 \| DISEASES 8972 \| MGAM \| 4.652 \| DISEASES 4514 \| MT-CO3 \| 2.578 \| DISEASES 23327 \| NEDD4L \| 1.414 \| DISEASES 4878 \| NPPA \| 1.038 \| DISEASES 4306 \| NR3C2 \| 4.613 \| DISEASES 56341 \| PRMT8 \| 1.925 \| DISEASES 57127 \| RHBG \| 2.856 \| DISEASES 6230 \| RPS25 \| 1.449 \| DISEASES 6329 \| SCN4A \| 3.556 \| DISEASES 6331 \| SCN5A \| 1.808 \| DISEASES 6338 \| SCNN1B \| 3.5 \| DISEASES 6446 \| SGK1 \| 1.878 \| DISEASES 6557 \| SLC12A1 \| 4.919 \| DISEASES 6559 \| SLC12A3 \| 6.363 \| DISEASES 51312 \| SLC25A37 \| 1.395 \| DISEASES 10861 \| SLC26A1 \| 1.701 \| DISEASES 1811 \| SLC26A3 \| 3.661 \| DISEASES 9498 \| SLC4A8 \| 1.996 \| DISEASES 6524 \| SLC5A2 \| 1.705 \| DISEASES 9576 \| SPAG6 \| 1.491 \| DISEASES 8428 \| STK24 \| 3.3 \| DISEASES 27347 \| STK39 \| 3.379 \| DISEASES 6888 \| TALDO1 \| 1.589 \| DISEASES 140803 \| TRPM6 \| 2.195 \| DISEASES 55503 \| TRPV6 \| 1.51 \| DISEASES 7422 \| VEGFA \| 1.153 \| DISEASES 7432 \| VIP \| 4.342 \| DISEASES
Locus	(Waiting for update.)

Disease ID	1507
Disease	hypokalemia
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:110) HP:0000822 \| Hypertension \| 22 HP:0001948 \| Alkalosis \| 21 HP:0200114 \| Metabolic alkalosis \| 19 HP:0003470 \| Inability to move \| 18 HP:0011675 \| Arrhythmias \| 16 HP:0001941 \| acidemia \| 12 HP:0003201 \| Rhabdomyolysis \| 11 HP:0001324 \| Muscular weakness \| 11 HP:0001942 \| Metabolic acidosis \| 10 HP:0002014 \| Diarrhea \| 7 HP:0002917 \| Low blood magnesium levels \| 6 HP:0002024 \| Intestinal malabsorption \| 6 HP:0001947 \| Renal tubular acidosis \| 6 HP:0004308 \| Ventricular arrhythmia \| 5 HP:0000859 \| Mineralocorticoid excess \| 5 HP:0002013 \| Emesis \| 5 HP:0004395 \| Malnutrition \| 4 HP:0003768 \| Periodic paralysis \| 4 HP:0001695 \| Cardiac arrest \| 4 HP:0001953 \| Diabetic ketosis \| 4 HP:0003074 \| High blood glucose \| 3 HP:0000083 \| Renal insufficiency \| 3 HP:0002273 \| Tetraparesis \| 3 HP:0003127 \| Low urine calcium levels \| 3 HP:0004756 \| Ventricular tachycardia \| 3 HP:0001635 \| Congestive heart failure \| 3 HP:0001649 \| Tachycardia \| 3 HP:0000103 \| Polyuria \| 3 HP:0002902 \| Hyponatremia \| 3 HP:0012531 \| Pain \| 3 HP:0001945 \| Fever \| 2 HP:0002480 \| Hepatic encephalopathy \| 2 HP:0001281 \| Tetany \| 2 HP:0001944 \| Dehydration \| 2 HP:0001664 \| Torsade de pointes \| 2 HP:0002170 \| Intracranial hemorrhage \| 2 HP:0002039 \| Anorexia \| 2 HP:0008341 \| Renal tubular acidosis, type I \| 2 HP:0002153 \| Elevated serum potassium levels \| 2 HP:0003072 \| Hypercalcemia \| 2 HP:0002664 \| Neoplasia \| 2 HP:0003256 \| Coagulopathy \| 2 HP:0001974 \| Leukocytosis \| 2 HP:0000127 \| Salt wasting \| 2 HP:0004934 \| Vascular calcification \| 2 HP:0005943 \| Respiratory arrest \| 1 HP:0002659 \| Increased tendency to fractures \| 1 HP:0000843 \| Hyperparathyroidism \| 1 HP:0000716 \| Depression \| 1 HP:0001919 \| Acute renal failure \| 1 HP:0000093 \| Proteinuria \| 1 HP:0030731 \| Carcinoma \| 1 HP:0001712 \| Left ventricular hypertrophy \| 1 HP:0030252 \| Absence of mature B cells \| 1 HP:0012233 \| Intramuscular haematoma \| 1 HP:0001508 \| Weight faltering \| 1 HP:0012188 \| Hyperemesis gravidarum \| 1 HP:0000969 \| Dropsy \| 1 HP:0030405 \| Pancreatic endocrine tumor \| 1 HP:0000815 \| Primary hypogonadism \| 1 HP:0011145 \| Symptomatic seizures \| 1 HP:0001993 \| Ketoacidosis \| 1 HP:0002315 \| Headaches \| 1 HP:0002045 \| Abnormally low body temperature \| 1 HP:0001892 \| Bleeding diathesis \| 1 HP:0000713 \| Agitation \| 1 HP:0001397 \| Hepatic steatosis \| 1 HP:0000975 \| Increased sweating \| 1 HP:0001578 \| Hypercortisolism \| 1 HP:0012735 \| Coughing \| 1 HP:0005977 \| Hypochloremic metabolic alkalosis \| 1 HP:0000846 \| Hypoadrenalism \| 1 HP:0006682 \| Premature ventricular contractions \| 1 HP:0002383 \| Encephalitis \| 1 HP:0002099 \| Asthma \| 1 HP:0001950 \| Respiratory alkalosis \| 1 HP:0006744 \| Adrenal carcinoma \| 1 HP:0004918 \| Hyperchloremic metabolic acidosis \| 1 HP:0007340 \| Lower limb weakness \| 1 HP:0003394 \| Muscle cramps \| 1 HP:0001714 \| Ventricular hypertrophy \| 1 HP:0002098 \| Respiratory distress \| 1 HP:0002150 \| Hypercalcinuria \| 1 HP:0002630 \| Fat malabsorption \| 1 HP:0000836 \| Overactive thyroid \| 1 HP:0000939 \| Osteoporosis \| 1 HP:0000848 \| Hyperreninemia \| 1 HP:0005115 \| arrhythmias, Supraventricular \| 1 HP:0001399 \| Liver failure \| 1 HP:0000017 \| Nocturia \| 1 HP:0003196 \| Short nose \| 1 HP:0002028 \| Chronic diarrhea \| 1 HP:0011741 \| Secondary hyperaldosteronism \| 1 HP:0003113 \| Low blood chloride levels \| 1 HP:0012272 \| Osborne waves \| 1 HP:0001903 \| Anemia \| 1 HP:0000738 \| Sensory hallucination \| 1 HP:0100522 \| Thymoma \| 1 HP:0001943 \| Hypoglycemia \| 1 HP:0002901 \| Hypocalcemia \| 1 HP:0005086 \| Knee osteoarthritis \| 1 HP:0007185 \| Loss of consciousness \| 1 HP:0003351 \| Decreased plasma renin activity \| 1 HP:0002900 \| Hypokalemia \| 1 HP:0008221 \| Enlarged adrenal glands \| 1 HP:0001663 \| Ventricular fibrillation \| 1 HP:0000124 \| Renal tubular defect \| 1 HP:0005110 \| Atrial fibrillation \| 1 HP:0002138 \| Subarachnoid hemorrhage \| 1 HP:0001250 \| Seizures \| 1

Disease ID	1507
Disease	hypokalemia
Manually Symptom	(Waiting for update.)
Text Mined Symptom	(Waiting for update.)

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

Text Mining Genotype(Total Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:0)
(Waiting for update.)

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Disease ID	1507
Disease	hypokalemia
Case	(Waiting for update.)

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