eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| hydatidiform mole | ||||
| Disease ID | 422 |
|---|---|
| Disease | hydatidiform mole |
| Definition | Trophoblastic hyperplasia associated with normal gestation, or molar pregnancy. It is characterized by the swelling of the CHORIONIC VILLI and elevated human CHORIONIC GONADOTROPIN. Hydatidiform moles or molar pregnancy may be categorized as complete or partial based on their gross morphology, histopathology, and karyotype. |
| Synonym | [m]hydatidiform mole nos [m]hydatidiform mole nos (morphologic abnormality) chorionic tumor classical hydatidiform mole gestational trophoblastic tumor, hydatidiform mole gtt, hydatidiform mole hydatid mole hydatid moles hydatidiform mole (disorder) hydatidiform mole (morphologic abnormality) hydatidiform mole [ambiguous] hydatidiform mole [disease/finding] hydatidiform mole gtt hydatidiform mole, no icd-o subtype hydatidiform mole, no icd-o subtype (morphologic abnormality) hydatidiform mole, no international classification of diseases for oncology subtype hydatidiform mole, no international classification of diseases for oncology subtype (morphologic abnormality) hydatidiform mole, nos hydatidiform moles molar pregn molar pregnancies molar pregnancy molar pregnancy (disorder) molar pregnancy with hydatid mole molar pregnancy with hydatidiform mole molar pregnancy with hydatidiform mole (disorder) molar pregnancy with hydatidiform mole (disorder) [ambiguous] molar pregnancy with vesicular mole molar pregnancy with vesicular mole (disorder) molar pregnancy, nos molars pregnancy mole mole (disorder) mole -retired- mole hydatidiform mole of pregnancy mole of pregnancy, nos mole pregnancy mole, hydatid mole, hydatidiform mole, nos moles pregnancy moles, hydatid moles, hydatidiform pregn molar pregnancies, molar pregnancy mole pregnancy, molar vesicular mole |
| Orphanet | |
| OMIM | |
| DOID | |
| ICD10 | |
| UMLS | C0020217 |
| MeSH | |
| SNOMED-CT | |
| Comorbidity | UMLS | Disease | Sentences' Count(Total Sentences:30) C0008497 | choriocarcinoma | 4 C0020550 | hyperthyroidism | 3 C0032987 | ectopic pregnancy | 3 C0025202 | melanoma | 2 C1135868 | gestational trophoblastic disease | 2 C0019343 | pemphigoid gestationis | 2 C0085083 | ovarian hyperstimulation syndrome | 2 C0152095 | trisomy 13 | 1 C0027706 | hereditary nephritis | 1 C0022658 | nephropathy | 1 C0013537 | eclampsia | 1 C0019114 | hemosiderosis | 1 C0018802 | congestive heart failure | 1 C0027726 | nephrotic syndrome | 1 C0022408 | arthropathy | 1 C0017105 | gas gangrene | 1 C0027697 | nephritis | 1 C0040127 | thyroid storm | 1 C0020538 | hypertension | 1 C0677608 | chorioangioma | 1 C0018801 | heart failure | 1 C0034150 | purpura | 1 C0034155 | thrombotic thrombocytopenic purpura | 1 C0030805 | pemphigoid | 1 C0878544 | cardiomyopathy | 1 C0745140 | hyperthyroid | 1 C0003857 | arteriovenous malformation | 1 C1135868 | gestational trophoblastic neoplasia | 1 C0040053 | thrombus | 1 C0032914 | preeclampsia | 1 |
| Curated Gene | Entrez_id | Symbol | Resource(Total Genes:1) |
| Inferring Gene | (Waiting for update.) |
| Text Mined Gene | (Waiting for update.) |
| Locus | (Waiting for update.) |
| Disease ID | 422 |
|---|---|
| Disease | hydatidiform mole |
| Manually Symptom | UMLS | Name(Total Manually Symptoms:13) C1608408 | malignant transformation C1135868 | trophoblastic disease C1135868 | gestational trophoblastic disease C1000483 | anemia C0553681 | hypofibrinogenemia C0040156 | thyrotoxicosis C0034065 | pulmonary embolism C0034063 | pulmonary edema C0032914 | pre-eclampsia C0030584 | parovarian cyst C0020550 | hyperthyroidism C0013537 | eclampsia C0000727 | acute abdomen |
| Text Mined Symptom | UMLS | Name | Sentences' Count(Total Symptoms:5) C1135868 | trophoblastic disease | 2 C0020550 | hyperthyroidism | 2 C0032914 | preeclampsia | 1 C1608408 | malignant transformation | 1 C0013537 | eclampsia | 1 |
Manually Genotype(Total Text Mining Genotypes:0) |
|---|
| (Waiting for update.) |
Text Mining Genotype(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
All Snps(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Annotation(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
Mapped by lexical matching(Total Items:2) | ||||
|---|---|---|---|---|
| HP ID | HP Name | MP ID | MP Name | Annotation |
| HP:0000119 | Abnormality of the genitourinary system | MP:0004251 | failure of heart looping | failure of the primitive heart tube to loop asymmetrically during early development |
| HP:0002017 | Nausea and vomiting | MP:0010426 | abnormal heart and great artery attachment | any anomaly in the in the position or pattern of the connection site of the heart to any of the great arteries, including the pulmonary artery and aorta |
Mapped by homologous gene(Total Items:6) | ||||
|---|---|---|---|---|
| HP ID | HP Name | MP ID | MP Name | Annotation |
| HP:0000836 | Hyperthyroidism | MP:0020169 | increased thyroid gland weight | higher than average weight of the thyroid gland |
| HP:0005268 | Spontaneous abortion | MP:0020040 | decreased bone ossification | decrease in the formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance |
| HP:0002017 | Nausea and vomiting | MP:0020220 | decreased tear production | decreased production of the amount of fluid produced in the eye |
| HP:0100602 | Preeclampsia | MP:0014169 | decreased brown adipose tissue mass | decreased physical bulk or volume of brown adipose tissue |
| HP:0001903 | Anemia | MP:0020316 | decreased vascular endothelial cell proliferation | decrease in the expansion rate of any vascular endothelial cell population by cell division |
| HP:0000119 | Abnormality of the genitourinary system | MP:0013348 | adenohypophysis hyperplasia | overdevelopment or increased size of the anterior lobe of the pituitary gland, usually due to increased cell number |
| Disease ID | 422 |
|---|---|
| Disease | hydatidiform mole |
| Case | (Waiting for update.) |