eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| hepatorenal syndrome | ||||
| Disease ID | 695 |
|---|---|
| Disease | hepatorenal syndrome |
| Definition | Functional KIDNEY FAILURE in patients with liver disease, usually LIVER CIRRHOSIS or portal hypertension (HYPERTENSION, PORTAL), and in the absence of intrinsic renal disease or kidney abnormality. It is characterized by intense renal vasculature constriction, reduced renal blood flow, OLIGURIA, and sodium retention. |
| Synonym | failure hepatorenal hepatorenal failure hepatorenal syndrome (disorder) hepatorenal syndrome [disease/finding] heyd syndrome hrf - hepatorenal failure renal failure secondary to liver disease renal failure secondary to liver disease hepatorenal syndrome syndrome hepatorenal syndrome, hepatorenal urohepatic syndrome |
| DOID | |
| ICD10 | |
| UMLS | C0019212 |
| MeSH | |
| SNOMED-CT | |
| Comorbidity | UMLS | Disease | Sentences' Count(Total Sentences:14) C0023890 | cirrhosis | 18 C0023890 | liver cirrhosis | 7 C0035078 | renal failure | 3 C0019158 | hepatitis | 3 C0023891 | alcoholic liver cirrhosis | 3 C0023895 | liver disease | 2 C0019196 | hepatitis c | 2 C0040558 | toxoplasmosis | 1 C0031154 | peritonitis | 1 C0020541 | portal hypertension | 1 C0020538 | hypertension | 1 C0002726 | amyloidosis | 1 C0021390 | inflammatory bowel disease | 1 C0021831 | bowel disease | 1 |
| Curated Gene | Entrez_id | Symbol | Resource(Total Genes:2) |
| Inferring Gene | Entrez_id | Symbol | Resource(Total Genes:3) |
| Text Mined Gene | Entrez_id | Symbol | Score | Resource(Total Genes:27) 25820 | ARIH1 | 1.991 | DISEASES 444 | ASPH | 1.175 | DISEASES 551 | AVP | 3.818 | DISEASES 554 | AVPR2 | 1.76 | DISEASES 567 | B2M | 1.684 | DISEASES 1029 | CDKN2A | 1.085 | DISEASES 1471 | CST3 | 3.608 | DISEASES 1759 | DNM1 | 1.201 | DISEASES 1906 | EDN1 | 3.305 | DISEASES 27022 | FOXD3 | 1.245 | DISEASES 2641 | GCG | 1.885 | DISEASES 8443 | GNPAT | 2.731 | DISEASES 26762 | HAVCR1 | 3 | DISEASES 3710 | ITPR3 | 1.207 | DISEASES 10724 | MGEA5 | 1.422 | DISEASES 4881 | NPR1 | 1.281 | DISEASES 8504 | PEX3 | 2.303 | DISEASES 5830 | PEX5 | 4.718 | DISEASES 6019 | RLN2 | 1.77 | DISEASES 80196 | RNF34 | 2.767 | DISEASES 10478 | SLC25A17 | 1.423 | DISEASES 55974 | SLC50A1 | 1.535 | DISEASES 6905 | TBCE | 1.73 | DISEASES 7053 | TGM3 | 1.116 | DISEASES 7124 | TNF | 1.362 | DISEASES 51366 | UBR5 | 1.071 | DISEASES 124220 | ZG16B | 2.982 | DISEASES |
| Locus | (Waiting for update.) |
| Disease ID | 695 |
|---|---|
| Disease | hepatorenal syndrome |
| Integrated Phenotype | (Waiting for update.) |
| Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:15) HP:0001394 | Hepatic cirrhosis | 19 HP:0001541 | Ascites | 5 HP:0001399 | Liver failure | 4 HP:0000083 | Renal insufficiency | 4 HP:0001919 | Acute renal failure | 3 HP:0012115 | Liver inflammation | 3 HP:0100626 | Chronic hepatic failure | 2 HP:0100598 | Pulmonary oedema | 1 HP:0000822 | Hypertension | 1 HP:0002586 | Peritonitis | 1 HP:0011034 | Amyloid disease | 1 HP:0001409 | Portal hypertension | 1 HP:0012280 | Hepatic amyloidosis | 1 HP:0001945 | Fever | 1 HP:0100806 | Sepsis | 1 |
| Disease ID | 695 |
|---|---|
| Disease | hepatorenal syndrome |
| Manually Symptom | UMLS | Name(Total Manually Symptoms:4) |
| Text Mined Symptom | UMLS | Name | Sentences' Count(Total Symptoms:2) |
Manually Genotype(Total Text Mining Genotypes:0) |
|---|
| (Waiting for update.) |
Text Mining Genotype(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
All Snps(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Annotation(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
Mapped by lexical matching(Total Items:0) |
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| (Waiting for update.) |
Mapped by homologous gene(Total Items:0) |
|---|
| (Waiting for update.) |
| Disease ID | 695 |
|---|---|
| Disease | hepatorenal syndrome |
| Case | (Waiting for update.) |