eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| foodborne botulism | ||||
| Disease ID | 1263 |
|---|---|
| Disease | foodborne botulism |
| Definition | Botulism that is caused by consuming food or beverage that contains the botulinum toxin. |
| Synonym | botulism food poisoning botulism, foodborne botulisms, foodborne food poisoning due to clostridium botulinum food poisoning due to clostridium botulinum toxin foodborne botulism (disorder) foodborne botulisms |
| Orphanet | |
| DOID | |
| ICD10 | |
| UMLS | C1739094 |
| SNOMED-CT | |
| Curated Gene | (Waiting for update.) |
| Inferring Gene | (Waiting for update.) |
| Text Mined Gene | Entrez_id | Symbol | Score | Resource(Total Genes:10) 262 | AMD1 | 2.618 | DISEASES 26190 | FBXW2 | 4.239 | DISEASES 2813 | GP2 | 2.929 | DISEASES 4905 | NSF | 2.949 | DISEASES 142 | PARP1 | 1.058 | DISEASES 5077 | PAX3 | 2.332 | DISEASES 56980 | PRDM10 | 2.347 | DISEASES 22987 | SV2C | 4.176 | DISEASES 127833 | SYT2 | 6.003 | DISEASES 10732 | TCFL5 | 3.027 | DISEASES |
| Locus | (Waiting for update.) |
| Disease ID | 1263 |
|---|---|
| Disease | foodborne botulism |
| Integrated Phenotype | HPO | Name(Total Integrated Phenotypes:19) HP:0003470 | Paralysis HP:0011499 | Mydriasis HP:0000016 | Urinary retention HP:0001324 | Muscle weakness HP:0002014 | Diarrhea HP:0002015 | Dysphagia HP:0011675 | Arrhythmia HP:0100021 | Cerebral palsy HP:0002019 | Constipation HP:0002027 | Abdominal pain HP:0002017 | Nausea and vomiting HP:0002747 | Respiratory insufficiency due to muscle weakness HP:0006597 | Diaphragmatic paralysis HP:0006543 | Cardiorespiratory arrest HP:0006824 | Cranial nerve paralysis HP:0000651 | Diplopia HP:0000217 | Xerostomia HP:0000508 | Ptosis HP:0001260 | Dysarthria |
| Text Mined Phenotype | (Waiting for update.) |
| Disease ID | 1263 |
|---|---|
| Disease | foodborne botulism |
| Manually Symptom | (Waiting for update.) |
| Text Mined Symptom | (Waiting for update.) |
Manually Genotype(Total Text Mining Genotypes:0) |
|---|
| (Waiting for update.) |
Text Mining Genotype(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
All Snps(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Annotation(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
Mapped by lexical matching(Total Items:5) | ||||
|---|---|---|---|---|
| HP ID | HP Name | MP ID | MP Name | Annotation |
| HP:0001324 | Muscle weakness | MP:0000746 | weakness | state of being infirm or less strong than normal |
| HP:0002017 | Nausea and vomiting | MP:0010426 | abnormal heart and great artery attachment | any anomaly in the in the position or pattern of the connection site of the heart to any of the great arteries, including the pulmonary artery and aorta |
| HP:0006824 | Cranial nerve paralysis | MP:0006303 | abnormal retinal nerve fiber layer morphology | any structural anomaly of the layer of the retina formed by expansion of the fibers of the optic nerve |
| HP:0006597 | Diaphragmatic paralysis | MP:0000755 | hindlimb paralysis | loss of power of voluntary movement in the muscles of the hindlimb through injury or disease of it or its nerve supply |
| HP:0002747 | Respiratory insufficiency due to muscle weakness | MP:0000748 | progressive muscle weakness | increasing loss of muscle strength over time |
Mapped by homologous gene(Total Items:19) | ||||
|---|---|---|---|---|
| HP ID | HP Name | MP ID | MP Name | Annotation |
| HP:0000217 | Xerostomia | MP:0020039 | increased bone ossification | increase in the formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance |
| HP:0000651 | Diplopia | MP:0020187 | altered susceptibility to prion infection | altered likelihood that an organism will develop ill effects from the small proteinaceous infectious particles which are resistant to inactivation by procedures that modify nucleic acids and which contain an abnormal isoform of a cellular protein that is |
| HP:0100021 | Cerebral palsy | MP:0013026 | decreased Ly6C low monocyte number | decrease in the number of monocytes that express low levels of Ly6C and low MHC class II that represent a subset of patrolling monocytes |
| HP:0011675 | Arrhythmia | MP:0020309 | increased creatine kinase activity | increased ability of to catalyze the reaction: ATP + creatine = N-phosphocreatine + ADP + 2 H(+). |
| HP:0000508 | Ptosis | MP:0020321 | increased vascular endothelial cell apoptosis | increase in the timing or the number of vascular endothelial cells undergoing programmed cell death |
| HP:0002027 | Abdominal pain | MP:0020220 | decreased tear production | decreased production of the amount of fluid produced in the eye |
| HP:0002747 | Respiratory insufficiency due to muscle weakness | MP:0020220 | decreased tear production | decreased production of the amount of fluid produced in the eye |
| HP:0002015 | Dysphagia | MP:0020329 | decreased capillary density | reduction in the number of capillaries in a given cross-sectional area of a tissue |
| HP:0002019 | Constipation | MP:0020234 | decreased basal metabolism | decrease in heat production of an organism at the lowest level of cell chemistry in an inactive, awake, and fasting state |
| HP:0003470 | Paralysis | MP:0013659 | abnormal erythroid lineage cell morphology | any structural anomaly of an immature or mature cell in the lineage leading to and including erythrocytes |
| HP:0011499 | Mydriasis | MP:0009862 | abnormal aorta elastic tissue morphology | any structural anomaly of the dense connective tissue which contains predominantly elastic fibers and is found in the aorta wall |
| HP:0006597 | Diaphragmatic paralysis | MP:0014074 | increased brain glycogen level | greater than the normal concentration of a readily converted carbohydrate reserve in brain |
| HP:0002014 | Diarrhea | MP:0020220 | decreased tear production | decreased production of the amount of fluid produced in the eye |
| HP:0002017 | Nausea and vomiting | MP:0020220 | decreased tear production | decreased production of the amount of fluid produced in the eye |
| HP:0001260 | Dysarthria | MP:0020329 | decreased capillary density | reduction in the number of capillaries in a given cross-sectional area of a tissue |
| HP:0001324 | Muscle weakness | MP:0020309 | increased creatine kinase activity | increased ability of to catalyze the reaction: ATP + creatine = N-phosphocreatine + ADP + 2 H(+). |
| HP:0006543 | Cardiorespiratory arrest | MP:0011100 | preweaning lethality, complete penetrance | death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age) |
| HP:0000016 | Urinary retention | MP:0020187 | altered susceptibility to prion infection | altered likelihood that an organism will develop ill effects from the small proteinaceous infectious particles which are resistant to inactivation by procedures that modify nucleic acids and which contain an abnormal isoform of a cellular protein that is |
| HP:0006824 | Cranial nerve paralysis | MP:0020137 | decreased bone mineralization | decrease in the rate at which minerals are deposited into bone |
| Disease ID | 1263 |
|---|---|
| Disease | foodborne botulism |
| Case | (Waiting for update.) |