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	eosinophilia

Disease ID	873
Disease	eosinophilia
Definition	Abnormal increase of EOSINOPHILS in the blood, tissues or organs.
Synonym	eosinophilia (disorder) eosinophilia (disorder) [ambiguous] eosinophilia [disease/finding] eosinophilia nos eosinophilia nos (disorder) eosinophilia, nos eosinophilias eosinophilic leucocytosis eosinophilic leukocytosis eosinophils increased high blood eosinophil count high eosinophil count increased eosinophils
DOID	DOID:999
ICD10	ICD10CM:D72.1
UMLS	C0014457
MeSH	D004802
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:178) C0015230 \| rash \| 131 C0002989 \| angiolymphoid hyperplasia \| 93 C0002989 \| angiolymphoid hyperplasia with eosinophilia \| 21 C0004096 \| asthma \| 20 C2607914 \| allergic rhinitis \| 14 C0023418 \| leukemia \| 13 C0035455 \| rhinitis \| 11 C0042384 \| vasculitis \| 8 C0007137 \| epidermoid carcinoma \| 6 C0206694 \| mucoepidermoid carcinoma \| 6 C0023470 \| myeloid leukemia \| 5 C0023467 \| acute myeloid leukemia \| 5 C0023418 \| leukaemia \| 4 C0023449 \| acute lymphoblastic leukemia \| 4 C0002871 \| anemia \| 4 C0018916 \| hemangioma \| 4 C0024299 \| lymphoma \| 4 C0023448 \| lymphoblastic leukemia \| 4 C0205788 \| epithelioid hemangioma \| 4 C0155877 \| allergic asthma \| 4 C0014868 \| esophagitis \| 3 C0040553 \| toxocariasis \| 3 C0376545 \| hematologic malignancies \| 2 C0007570 \| celiac disease \| 2 C0004096 \| bronchial asthma \| 2 C0040053 \| thrombosis \| 2 C0341106 \| eosinophilic esophagitis \| 2 C0041296 \| tuberculosis \| 2 C0035078 \| renal failure \| 2 C0009319 \| colitis \| 2 C0023470 \| myelogenous leukaemia \| 2 C0025289 \| meningitis \| 2 C0036323 \| schistosomiasis \| 2 C0032285 \| pneumonitis \| 2 C0024899 \| mastocytosis \| 2 C0032285 \| pulmonary inflammation \| 2 C0013395 \| dyspepsia \| 2 C0031039 \| pericardial effusion \| 2 C0276688 \| pulmonary cryptococcosis \| 2 C0010414 \| cryptococcosis \| 2 C0442874 \| neuropathy \| 2 C0003864 \| arthritis \| 2 C0017178 \| gastrointestinal disorders \| 2 C0206141 \| hypereosinophilic syndrome \| 2 C0011847 \| diabetes \| 2 C0020455 \| hypergammaglobulinemia \| 2 C0022660 \| acute renal failure \| 2 C0221013 \| systemic mastocytosis \| 2 C0023449 \| acute lymphoblastic leukaemia \| 2 C0017178 \| gastrointestinal disorder \| 2 C0005684 \| bladder cancer \| 2 C0037753 \| sparganosis \| 1 C1261473 \| sarcoma \| 1 C0018799 \| cardiac disease \| 1 C0006277 \| bronchitis \| 1 C0027022 \| myeloproliferative neoplasms \| 1 C0039128 \| syphilis \| 1 C0001418 \| adenocarcinoma \| 1 C0021053 \| immune disorder \| 1 C0026986 \| myelodysplastic syndrome \| 1 C0154652 \| eosinophilic meningitis \| 1 C0747256 \| parasitic infection \| 1 C0023449 \| acute lymphatic leukaemia \| 1 C0015645 \| fasciitis \| 1 C0155877 \| atopic asthma \| 1 C0023530 \| leucopenia \| 1 C0003873 \| rheumatoid arthritis \| 1 C0025309 \| meningoencephalitis \| 1 C0038325 \| stevens johnson syndrome \| 1 C0598894 \| monocytic leukemia \| 1 C0035460 \| vasomotor rhinitis \| 1 C0011854 \| type 1 diabetes \| 1 C0242379 \| lung cancer \| 1 C0023470 \| myelogenous leukemia \| 1 C0027022 \| myeloproliferative disorders \| 1 C0042109 \| urticaria \| 1 C0024301 \| follicular lymphoma \| 1 C0036262 \| scabies \| 1 C0040896 \| trichinellosis \| 1 C0085642 \| livedo reticularis \| 1 C0027051 \| myocardial infarction \| 1 C0011603 \| dermatitis \| 1 C0030499 \| parasitic disease \| 1 C0037274 \| skin disease \| 1 C0036202 \| sarcoidosis \| 1 C0037199 \| sinusitis \| 1 C0026718 \| mucormycosis \| 1 C0014070 \| encephalomyelitis \| 1 C0041327 \| pulmonary tuberculosis \| 1 C0020538 \| hypertension \| 1 C0031117 \| peripheral neuropathy \| 1 C0013502 \| hydatidosis \| 1 C0022398 \| hyper-ige syndrome \| 1 C0041188 \| tropical pyomyositis \| 1 C0879615 \| stromal tumor \| 1 C1704275 \| pyomyositis \| 1 C0836924 \| thrombocytosis \| 1 C0036421 \| systemic sclerosis \| 1 C1527383 \| morphea \| 1 C0014869 \| reflux esophagitis \| 1 C0007177 \| cardiac tamponade \| 1 C0013182 \| drug hypersensitivity \| 1 C0007196 \| restrictive cardiomyopathy \| 1 C0021053 \| immune disorders \| 1 C0017168 \| esophageal reflux \| 1 C0033838 \| kimura's disease \| 1 C1956391 \| temporal arteritis \| 1 C1266042 \| chromophobe renal cell carcinoma \| 1 C0398689 \| x-linked hyper-igm syndrome \| 1 C0026975 \| myelitis \| 1 C0031154 \| peritonitis \| 1 C0017155 \| menetrier's disease \| 1 C1527407 \| eosinophilic pneumonia \| 1 C0026948 \| mycosis fungoides \| 1 C0042769 \| virus infection \| 1 C0205945 \| spindle cell sarcoma \| 1 C0027051 \| myocardial infarct \| 1 C0152013 \| lung adenocarcinoma \| 1 C0023448 \| lymphatic leukaemia \| 1 C0017168 \| gastro-oesophageal reflux \| 1 C0238106 \| clostridium difficile colitis \| 1 C0010073 \| coronary vasospasm \| 1 C0021053 \| immune disease \| 1 C0023467 \| acute myelogenous leukemia \| 1 C0024115 \| pulmonary disease \| 1 C0014848 \| achalasia \| 1 C0023473 \| chronic myelogenous leukaemia \| 1 C0017168 \| oesophageal reflux \| 1 C0017536 \| giardiasis \| 1 C0376545 \| hematological malignancies \| 1 C0272236 \| hyper-igm syndrome \| 1 C0010692 \| cystitis \| 1 C0026764 \| multiple myeloma \| 1 C0026946 \| mycosis \| 1 C0376545 \| hematologic cancer \| 1 C0008680 \| chronic eosinophilic pneumonia \| 1 C0037274 \| dermatosis \| 1 C0004352 \| autism \| 1 C0023467 \| acute myelogenous leukaemia \| 1 C0011991 \| diarrhoea \| 1 C0033860 \| psoriasis \| 1 C0006271 \| bronchiolitis \| 1 C0079748 \| lymphoblastic lymphoma \| 1 C0030499 \| parasitosis \| 1 C0027059 \| myocarditis \| 1 C0028738 \| nystagmus \| 1 C0037280 \| infestation \| 1 C0037998 \| splenic infarction \| 1 C0162316 \| iron deficiency anemia \| 1 C0038463 \| strongyloidiasis \| 1 C0149985 \| secondary syphilis \| 1 C0040053 \| thrombus \| 1 C1261473 \| sarcomas \| 1 C0878544 \| cardiomyopathy \| 1 C0014742 \| erythema multiforme \| 1 C0206698 \| cholangiocellular carcinoma \| 1 C0024894 \| mastitis \| 1 C0008325 \| cholecystitis \| 1 C0027022 \| myeloproliferative disorder \| 1 C0021831 \| enteropathy \| 1 C0027121 \| myositis \| 1 C0376358 \| prostate cancer \| 1 C0032231 \| pleuritis \| 1 C0007137 \| squamous cell carcinoma \| 1 C0030805 \| bullous pemphigoid \| 1 C0238198 \| gastrointestinal stromal tumor \| 1 C0079731 \| b cell lymphoma \| 1 C0030326 \| panniculitis \| 1 C0018552 \| hamartoma \| 1 C0019158 \| hepatitis \| 1 C0030499 \| parasitic diseases \| 1 C0007134 \| renal cell carcinoma \| 1 C0022573 \| keratoconjunctivitis \| 1 C0015652 \| fascioliasis \| 1 C0021845 \| bowel perforation \| 1 C0004763 \| barrett's esophagus \| 1 C0023418 \| leukaemias \| 1 C0026764 \| myeloma \| 1
Curated Gene	Entrez_id \| Symbol \| Resource(Total Genes:2) 3567 \| IL5 \| CTD_human 81858 \| SHARPIN \| CTD_human
Inferring Gene	Entrez_id \| Symbol \| Resource(Total Genes:5) 3586 \| IL10 \| CIPHER 3562 \| IL3 \| CIPHER 3567 \| IL5 \| CIPHER;CTD_human 6778 \| STAT6 \| CIPHER 81858 \| SHARPIN \| CTD_human
Text Mined Gene	(Waiting for update.)
Locus	(Waiting for update.)

Disease ID	873
Disease	eosinophilia
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:113) HP:0001974 \| Leukocytosis \| 27 HP:0002099 \| Asthma \| 25 HP:0003193 \| Allergic rhinitis \| 15 HP:0002664 \| Neoplasia \| 14 HP:0001909 \| Leukemia \| 13 HP:0100665 \| Angiooedema \| 13 HP:0012384 \| Nasal inflammation \| 13 HP:0002113 \| Pulmonary infiltrates \| 9 HP:0002633 \| Vasculitis \| 8 HP:0001945 \| Fever \| 8 HP:0030731 \| Carcinoma \| 7 HP:0012531 \| Pain \| 6 HP:0004808 \| Acute myelogenous leukemia \| 6 HP:0012324 \| Myeloid leukemia \| 5 HP:0002665 \| Lymphoma \| 5 HP:0002027 \| Abdominal pain \| 4 HP:0100633 \| Inflammation of the esophagus \| 4 HP:0001028 \| Strawberry mark \| 4 HP:0001903 \| Anemia \| 4 HP:0006721 \| Acute lymphocytic leukemia \| 4 HP:0012393 \| Allergy \| 3 HP:0002015 \| Swallowing difficulty \| 3 HP:0001019 \| Exfoliative dermititis \| 3 HP:0001541 \| Ascites \| 2 HP:0012735 \| Coughing \| 2 HP:0001369 \| Arthritis \| 2 HP:0002583 \| Colitis \| 2 HP:0002960 \| Autoimmune condition \| 2 HP:0002721 \| Immunodeficiency \| 2 HP:0003326 \| Muscle pain \| 2 HP:0009725 \| Bladder neoplasm \| 2 HP:0002020 \| Heartburn \| 2 HP:0002716 \| Lymph node hyperplasia \| 2 HP:0030828 \| Wheezing \| 2 HP:0010783 \| Erythema \| 2 HP:0011950 \| Bronchiolitis \| 2 HP:0000988 \| Exanthem \| 2 HP:0001919 \| Acute renal failure \| 2 HP:0010702 \| Hypergammaglobulinaemia \| 2 HP:0001287 \| Meningitis \| 2 HP:0100495 \| Mastocytosis \| 2 HP:0002608 \| Celiac disease \| 2 HP:0001698 \| Pericardial effusions \| 2 HP:0100582 \| Nasal polyps \| 2 HP:0000083 \| Renal insufficiency \| 2 HP:0001894 \| Thrombocytosis \| 1 HP:0002152 \| Hyperproteinemia \| 1 HP:0012190 \| T cell lymphoma \| 1 HP:0000969 \| Dropsy \| 1 HP:0001025 \| Hives \| 1 HP:0002863 \| Myelodysplastic syndrome \| 1 HP:0004820 \| Acute myelomonocytic leukemia \| 1 HP:0002242 \| Enteropathy \| 1 HP:0005584 \| Renal cell carcinoma \| 1 HP:0010566 \| Hamartoma \| 1 HP:0200119 \| Acute liver inflammation \| 1 HP:0002240 \| Enlarged liver \| 1 HP:0000965 \| Livedo reticularis \| 1 HP:0011947 \| Respiratory infection \| 1 HP:0012819 \| Myocarditis \| 1 HP:0006515 \| Interstitial pneumonitis \| 1 HP:0002571 \| Achalasia \| 1 HP:0012191 \| B-cell lymphoma \| 1 HP:0100723 \| Gastrointestinal stroma tumor \| 1 HP:0008066 \| Skin bullae \| 1 HP:0002860 \| Squamous cell carcinoma \| 1 HP:0000978 \| Bruisability \| 1 HP:0012089 \| Arteritis \| 1 HP:0100614 \| Muscle inflammation \| 1 HP:0001096 \| Keratoconjunctivitis \| 1 HP:0001370 \| Rheumatoid arthritis \| 1 HP:0012387 \| Bronchitis \| 1 HP:0100242 \| Sarcoma \| 1 HP:0011134 \| Mild fever \| 1 HP:0001631 \| Atria septal defect \| 1 HP:0001658 \| Myocardial infarction \| 1 HP:0012115 \| Liver inflammation \| 1 HP:0003270 \| Distended abdomen \| 1 HP:0001824 \| Weight loss \| 1 HP:0100580 \| Barrett's esophagus \| 1 HP:0100780 \| Conjunctival hamartoma \| 1 HP:0100749 \| Thoracic pain \| 1 HP:0003765 \| Psoriasis \| 1 HP:0012344 \| Morphea \| 1 HP:0005547 \| Myeloproliferative disorder \| 1 HP:0002097 \| Pulmonary emphysema \| 1 HP:0001482 \| Subcutaneous nodule \| 1 HP:0001723 \| Restrictive cardiomyopathy \| 1 HP:0100806 \| Sepsis \| 1 HP:0001297 \| Cerebral vascular events \| 1 HP:0000989 \| pruritis \| 1 HP:0003212 \| Elevated serum IgE \| 1 HP:0002102 \| Pleuritis \| 1 HP:0000822 \| Hypertension \| 1 HP:0002586 \| Peritonitis \| 1 HP:0000246 \| Sinus inflammation \| 1 HP:0000639 \| Nystagmus \| 1 HP:0001082 \| Cholecystitis \| 1 HP:0030078 \| Lung adenocarcinoma \| 1 HP:0012490 \| Inflammation of fat tissue \| 1 HP:0100537 \| Inflammation of the fascia \| 1 HP:0002013 \| Emesis \| 1 HP:0011227 \| Elevated C-reactive protein level \| 1 HP:0009830 \| Peripheral neuritis \| 1 HP:0000717 \| Autism \| 1 HP:0012378 \| Fatigue \| 1 HP:0001891 \| Iron-deficiency anemia \| 1 HP:0006775 \| Multiple myeloma \| 1 HP:0012486 \| Inflammation of spinal cord \| 1 HP:0004387 \| Enterocolitis \| 1 HP:0002094 \| Dyspnea \| 1 HP:0001638 \| Cardiomyopathy \| 1 HP:0012125 \| Prostate cancer \| 1

Disease ID	873
Disease	eosinophilia
Manually Symptom	UMLS \| Name(Total Manually Symptoms:57) C2697391 \| rheumatoid arthritis C2364118 \| weakness C1963274 \| vasculitis C1963178 \| myelitis C1963084 \| colitis C1961102 \| lymphoblastic lymphoma C1961102 \| acute lymphoblastic leukemia C1801950 \| g syndrome C1546654 \| granuloma C0947961 \| atopic disorders C0796110 \| w syndrome C0752303 \| urological manifestations C0699791 \| gastric carcinoma C0684249 \| lung cancer C0520463 \| chronic active hepatitis C0497156 \| lymphadenopathy C0334463 \| malignant fibrous histiocytoma C0264666 \| endomyocardial disease C0262988 \| cutaneous vasculitis C0238462 \| medullary thyroid carcinoma C0235896 \| pulmonary infiltration C0235896 \| pulmonary infiltrates C0221013 \| systemic mastocytosis C0221013 \| systemic mast cell disease C0155686 \| acute myocarditis C0152013 \| adenocarcinoma of the lung C0085669 \| acute leukemia C0079731 \| b-cell lymphoma C0040053 \| thrombosis C0039070 \| syncope C0037284 \| skin lesions C0037274 \| skin disease C0034150 \| purpura C0030499 \| parasitic diseases C0027022 \| myeloproliferative disorder C0027022 \| myeloid neoplasm C0026986 \| myelodysplastic syndrome C0026848 \| muscle disorders C0026764 \| plasma cell myeloma C0024305 \| non-hodgkin's lymphoma C0024115 \| lung diseases C0023493 \| adult t cell leukemia C0023467 \| acute myeloid leukemia C0023467 \| acute myelogenous leukaemia C0023449 \| acute lymphocytic leukemia (all) C0022660 \| acute renal failure C0019618 \| histiocytosis C0019214 \| hepatosplenomegaly C0018916 \| hemangioma C0015230 \| skin rash C0013604 \| oedema C0010073 \| coronary vasospasm C0010073 \| coronary artery spasm C0009324 \| ulcerative colitis C0005424 \| biliary tract disease C0002963 \| variant angina C0002940 \| aneurysms
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:24) C0027022 \| myeloid neoplasm \| 15 C0018188 \| granuloma \| 11 C0042384 \| vasculitis \| 8 C0235896 \| pulmonary infiltrates \| 8 C0023467 \| acute myeloid leukemia \| 5 C0018916 \| hemangioma \| 4 C0023449 \| acute lymphoblastic leukemia \| 4 C0040053 \| thrombosis \| 2 C0235896 \| pulmonary infiltration \| 2 C0037284 \| skin lesions \| 2 C0015230 \| skin rash \| 2 C0022660 \| acute renal failure \| 2 C0221013 \| systemic mastocytosis \| 2 C0009319 \| colitis \| 2 C0010073 \| coronary vasospasm \| 1 C0030499 \| parasitic diseases \| 1 C0242379 \| lung cancer \| 1 C0079748 \| lymphoblastic lymphoma \| 1 C0024228 \| lymphadenopathy \| 1 C0023467 \| acute myelogenous leukaemia \| 1 C0003873 \| rheumatoid arthritis \| 1 C0026986 \| myelodysplastic syndrome \| 1 C0026975 \| myelitis \| 1 C0027022 \| myeloproliferative disorder \| 1

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

Text Mining Genotype(Total Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:19)
snpId	pubmedId	geneId	geneSymbol	diseaseId	sourceId	sentence	score	Year	geneSymbol_dbSNP	CHROMOSOME	POS	REF	ALT
rs121913507	26017288	3717	JAK2	umls:C0014457	BeFree	Thus, there is a clear prognostic and therapeutic rationale for detection of KIT D816V and JAK2 V617F in the diagnostic work up of eosinophilia.	0.001085767	2015	KIT	4	54733155	A	T
rs121913507	26017288	3815	KIT	umls:C0014457	BeFree	Thus, there is a clear prognostic and therapeutic rationale for detection of KIT D816V and JAK2 V617F in the diagnostic work up of eosinophilia.	0.001085767	2015	KIT	4	54733155	A	T
rs121913507	17628645	3815	KIT	umls:C0014457	BeFree	KIT D816V-associated systemic mastocytosis with eosinophilia and FIP1L1/PDGFRA-associated chronic eosinophilic leukemia are distinct entities.	0.001085767	2007	KIT	4	54733155	A	T
rs121917894	17476358	5897	RAG2	umls:C0014457	BeFree	These Rag2(R229Q/R229Q) mice showed oligoclonal T cells, absence of circulating B cells, and peripheral eosinophilia.	0.000271442	2007	RAG2;C11orf74	11	36593483	C	T,A
rs12619285	19860791	9173	IL1RL1	umls:C0014457	BeFree	We recruited 284 patients with NP in four participating hospitals in Belgium and 427 healthy controls, and genotyped 10 SNPs affecting eosinophilia (rs1420101 in IL1RL1, rs12619285 in IKZF2, rs4431128 in GATA2, rs4143832 in IL5, rs3184504 in SH2B3, rs2416257 in WDR36, rs2269426 in MHC, rs9494145 in MYB, rs748065 in GFRA2, and rs3939286 in IL33) using MALDI-TOF.	0.000814326	2010	LOC102725082	2	212959321	A	G
rs1420101	19860791	9173	IL1RL1	umls:C0014457	BeFree	We recruited 284 patients with NP in four participating hospitals in Belgium and 427 healthy controls, and genotyped 10 SNPs affecting eosinophilia (rs1420101 in IL1RL1, rs12619285 in IKZF2, rs4431128 in GATA2, rs4143832 in IL5, rs3184504 in SH2B3, rs2416257 in WDR36, rs2269426 in MHC, rs9494145 in MYB, rs748065 in GFRA2, and rs3939286 in IL33) using MALDI-TOF.	0.000814326	2010	IL1RL1	2	102341256	C	T
rs2269426	19860791	9173	IL1RL1	umls:C0014457	BeFree	We recruited 284 patients with NP in four participating hospitals in Belgium and 427 healthy controls, and genotyped 10 SNPs affecting eosinophilia (rs1420101 in IL1RL1, rs12619285 in IKZF2, rs4431128 in GATA2, rs4143832 in IL5, rs3184504 in SH2B3, rs2416257 in WDR36, rs2269426 in MHC, rs9494145 in MYB, rs748065 in GFRA2, and rs3939286 in IL33) using MALDI-TOF.	0.000814326	2010	TNXB	6	32108722	G	A
rs2416257	19860791	9173	IL1RL1	umls:C0014457	BeFree	We recruited 284 patients with NP in four participating hospitals in Belgium and 427 healthy controls, and genotyped 10 SNPs affecting eosinophilia (rs1420101 in IL1RL1, rs12619285 in IKZF2, rs4431128 in GATA2, rs4143832 in IL5, rs3184504 in SH2B3, rs2416257 in WDR36, rs2269426 in MHC, rs9494145 in MYB, rs748065 in GFRA2, and rs3939286 in IL33) using MALDI-TOF.	0.000814326	2010	WDR36	5	111099792	C	T
rs3184504	19860791	9173	IL1RL1	umls:C0014457	BeFree	We recruited 284 patients with NP in four participating hospitals in Belgium and 427 healthy controls, and genotyped 10 SNPs affecting eosinophilia (rs1420101 in IL1RL1, rs12619285 in IKZF2, rs4431128 in GATA2, rs4143832 in IL5, rs3184504 in SH2B3, rs2416257 in WDR36, rs2269426 in MHC, rs9494145 in MYB, rs748065 in GFRA2, and rs3939286 in IL33) using MALDI-TOF.	0.000814326	2010	SH2B3	12	111446804	T	C
rs376562815	23446743	4790	NFKB1	umls:C0014457	BeFree	Recombinant IL-33 isoform with the G171S substitution had approximately 50% of activity of normal isoform in NF-κB-dependent reporter assay, and reduced bioactivity (∼65% of normal) to provoke eosinophilia when injected into mice.	0.000271442	2013	NFKB1;LOC101929401	4	102576961	G	A
rs386626619	26017288	3717	JAK2	umls:C0014457	BeFree	Thus, there is a clear prognostic and therapeutic rationale for detection of KIT D816V and JAK2 V617F in the diagnostic work up of eosinophilia.	0.001085767	2015	NA	NA	NA	NA	NA
rs386626619	26017288	3815	KIT	umls:C0014457	BeFree	Thus, there is a clear prognostic and therapeutic rationale for detection of KIT D816V and JAK2 V617F in the diagnostic work up of eosinophilia.	0.001085767	2015	NA	NA	NA	NA	NA
rs3939286	19860791	9173	IL1RL1	umls:C0014457	BeFree	We recruited 284 patients with NP in four participating hospitals in Belgium and 427 healthy controls, and genotyped 10 SNPs affecting eosinophilia (rs1420101 in IL1RL1, rs12619285 in IKZF2, rs4431128 in GATA2, rs4143832 in IL5, rs3184504 in SH2B3, rs2416257 in WDR36, rs2269426 in MHC, rs9494145 in MYB, rs748065 in GFRA2, and rs3939286 in IL33) using MALDI-TOF.	0.000814326	2010	NA	9	6210099	T	C
rs4143832	19860791	9173	IL1RL1	umls:C0014457	BeFree	We recruited 284 patients with NP in four participating hospitals in Belgium and 427 healthy controls, and genotyped 10 SNPs affecting eosinophilia (rs1420101 in IL1RL1, rs12619285 in IKZF2, rs4431128 in GATA2, rs4143832 in IL5, rs3184504 in SH2B3, rs2416257 in WDR36, rs2269426 in MHC, rs9494145 in MYB, rs748065 in GFRA2, and rs3939286 in IL33) using MALDI-TOF.	0.000814326	2010	NA	5	132527285	T	G
rs4431128	19860791	9173	IL1RL1	umls:C0014457	BeFree	We recruited 284 patients with NP in four participating hospitals in Belgium and 427 healthy controls, and genotyped 10 SNPs affecting eosinophilia (rs1420101 in IL1RL1, rs12619285 in IKZF2, rs4431128 in GATA2, rs4143832 in IL5, rs3184504 in SH2B3, rs2416257 in WDR36, rs2269426 in MHC, rs9494145 in MYB, rs748065 in GFRA2, and rs3939286 in IL33) using MALDI-TOF.	0.000814326	2010	NA	3	128532835	C	T
rs748065	19860791	9173	IL1RL1	umls:C0014457	BeFree	We recruited 284 patients with NP in four participating hospitals in Belgium and 427 healthy controls, and genotyped 10 SNPs affecting eosinophilia (rs1420101 in IL1RL1, rs12619285 in IKZF2, rs4431128 in GATA2, rs4143832 in IL5, rs3184504 in SH2B3, rs2416257 in WDR36, rs2269426 in MHC, rs9494145 in MYB, rs748065 in GFRA2, and rs3939286 in IL33) using MALDI-TOF.	0.000814326	2010	NA	8	21820591	A	G
rs77375493	26017288	3815	KIT	umls:C0014457	BeFree	Thus, there is a clear prognostic and therapeutic rationale for detection of KIT D816V and JAK2 V617F in the diagnostic work up of eosinophilia.	0.001085767	2015	JAK2;INSL6	9	5073770	G	A,T
rs77375493	26017288	3717	JAK2	umls:C0014457	BeFree	Thus, there is a clear prognostic and therapeutic rationale for detection of KIT D816V and JAK2 V617F in the diagnostic work up of eosinophilia.	0.001085767	2015	JAK2;INSL6	9	5073770	G	A,T
rs9494145	19860791	9173	IL1RL1	umls:C0014457	BeFree	We recruited 284 patients with NP in four participating hospitals in Belgium and 427 healthy controls, and genotyped 10 SNPs affecting eosinophilia (rs1420101 in IL1RL1, rs12619285 in IKZF2, rs4431128 in GATA2, rs4143832 in IL5, rs3184504 in SH2B3, rs2416257 in WDR36, rs2269426 in MHC, rs9494145 in MYB, rs748065 in GFRA2, and rs3939286 in IL33) using MALDI-TOF.	0.000814326	2010	NA	6	135111414	T	C

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Disease ID	873
Disease	eosinophilia
Case	(Waiting for update.)