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	burkitt lymphoma

Disease ID	297
Disease	burkitt lymphoma
Definition	A form of undifferentiated malignant LYMPHOMA usually found in central Africa, but also reported in other parts of the world. It is commonly manifested as a large osteolytic lesion in the jaw or as an abdominal mass. B-cell antigens are expressed on the immature cells that make up the tumor in virtually all cases of Burkitt lymphoma. The Epstein-Barr virus (HERPESVIRUS 4, HUMAN) has been isolated from Burkitt lymphoma cases in Africa and it is implicated as the causative agent in these cases; however, most non-African cases are EBV-negative.
Synonym	[m]burkitt's tumor [m]burkitt's tumor nos [m]burkitt's tumor nos (morphologic abnormality) [m]burkitt's tumors [m]burkitt's tumors (morphologic abnormality) [m]burkitt's tumour [m]burkitt's tumour nos [m]burkitt's tumours acute lymphoblastic leukaemia, burkitt's type acute lymphoblastic leukaemia, mature b-cell type acute lymphoblastic leukemia, burkitt's type acute lymphoblastic leukemia, mature b-cell type b all b-all b-cell acute lymphoblastic leukaemia bl - burkitt's lymphoma burkitt cell leukaemia burkitt cell leukemia burkitt cell leukemia (morphologic abnormality) burkitt leukemia burkitt lymphoma (morphologic abnormality) burkitt lymphoma [disease/finding] burkitt lymphoma, nos burkitt lymphoma/leukaemia burkitt lymphoma/leukemia burkitt lymphoma/leukemia (morphologic abnormality) burkitt lymphomas burkitt tumor burkitt tumor [obs] burkitt tumour [obs] burkitt's cell leukaemia burkitt's cell leukemia burkitt's leukaemia burkitt's leukemia burkitt's lymphoma burkitt's lymphoma (clinical) burkitt's lymphoma (disorder) burkitt's lymphoma - disorder burkitt's lymphoma nos burkitt's lymphoma nos (disorder) burkitt's lymphoma of unspecified site burkitt's lymphoma of unspecified site (disorder) burkitt's lymphoma, nos burkitt's non-hodgkin's lymphoma burkitt's tumor burkitt's tumor [obs] burkitt's tumor or lymphoma burkitt's tumour burkitt's tumour [obs] burkitt's type malignant lymphoma - small non-cleaved burkitt's type malignant lymphoma - undifferentiated burkitts leukemia burkitts lymphoma burkitts tumor cell leukemia, burkitt fab l3 fab l3 [obs] l3 acute lymphoblastic leukemia l3 acute lymphocytic leukemia l3 acute lymphogenous leukemia l3 acute lymphoid leukemia l3 lymphocytic leukemia l3 lymphocytic leukemias leukemia, burkitt leukemia, burkitt cell leukemia, burkitt's leukemia, l3 lymphocytic leukemia, lymphoblastic, burkitt-type leukemia, lymphocytic, l3 leukemias, l3 lymphocytic lymphocytic leukemia, l3 lymphocytic leukemias, l3 lymphoma, burkitt lymphoma, burkitt's malignant lymphoma, burkitt's type malignant lymphoma, small noncleaved, burkitt's, diffuse malignant lymphoma, undifferentiated, burkitt type [obs] malignant lymphoma, undifferentiated, burkitt's type nhl, burkitt's non-hodgkin's lymphoma, burkitt's small non-cleaved cell lymphoma, burkitt's type tumor, burkitt tumor, burkitt's
Orphanet	ORPHANET:543 ORPHANET:99860
OMIM	OMIM:113970
DOID	DOID:8584
UMLS	C0006413
MeSH	D002051
SNOMED-CT	SNOMEDCT_US_2016_09_01:118617000
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:55) C0024299 \| lymphoma \| 5 C0079731 \| b-cell lymphoma \| 3 C0023418 \| leukemia \| 2 C0024530 \| malaria \| 2 C0024299 \| lymphomas \| 2 C0079731 \| b-cell lymphomas \| 2 C0006142 \| breast cancer \| 2 C0021933 \| intussusception \| 2 C0011334 \| caries \| 1 C0011334 \| dental caries \| 1 C0023470 \| myeloid leukemia \| 1 C0027051 \| myocardial infarct \| 1 C0151740 \| raised intracranial pressure \| 1 C0442874 \| neuropathy \| 1 C0007847 \| cervical cancer \| 1 C0019829 \| hodgkin lymphoma \| 1 C0085669 \| acute leukemia \| 1 C0020502 \| hyperparathyroidism \| 1 C0334634 \| mantle cell lymphoma \| 1 C0035078 \| renal failure \| 1 C0024437 \| age-related macular degeneration \| 1 C0037054 \| sickle cell trait \| 1 C0007113 \| rectal cancer \| 1 C0035455 \| rhinitis \| 1 C0242379 \| lung cancer \| 1 C0028326 \| noonan syndrome \| 1 C2607914 \| allergic rhinitis \| 1 C0175702 \| williams syndrome \| 1 C0020503 \| secondary hyperparathyroidism \| 1 C0013182 \| drug hypersensitivity \| 1 C0021359 \| infertility \| 1 C0162429 \| malnutrition \| 1 C0026946 \| fungal infection \| 1 C0302592 \| cervical ca \| 1 C0023467 \| acute myeloid leukemia \| 1 C0376358 \| prostate cancer \| 1 C0948201 \| alloimmunization \| 1 C0042769 \| virus infection \| 1 C0019196 \| hepatitis c \| 1 C0025149 \| medulloblastoma \| 1 C0021364 \| male infertility \| 1 C0023890 \| cirrhosis \| 1 C0024302 \| large cell lymphoma \| 1 C0009402 \| colorectal cancer \| 1 C0022660 \| acute renal failure \| 1 C0027051 \| myocardial infarction \| 1 C0242647 \| malt lymphoma \| 1 C0019158 \| hepatitis \| 1 C0001339 \| acute pancreatitis \| 1 C0024305 \| non-hodgkin lymphoma \| 1 C0040997 \| trigeminal neuralgia \| 1 C2700641 \| lymphoplasmacytic lymphoma \| 1 C0686377 \| cns metastasis \| 1 C0023418 \| leukaemia \| 1 C0019069 \| hemophilia \| 1
Curated Gene	Entrez_id \| Symbol \| Resource(Total Genes:16) 6929 \| TCF3 \| CTD_human 5979 \| RET \| CTD_human 4609 \| MYC \| CLINVAR;CTD_human;ORPHANET;UNIPROT 53947 \| A4GALT \| CTD_human 5091 \| PC \| CTD_human 8289 \| ARID1A \| CTD_human 5087 \| PBX1 \| CTD_human 3399 \| ID3 \| CTD_human 6597 \| SMARCA4 \| CTD_human 83416 \| FCRL5 \| UNIPROT 10693 \| CCT6B \| CTD_human 5295 \| PIK3R1 \| CTD_human 27164 \| SALL3 \| CTD_human 10841 \| FTCD \| CTD_human 27113 \| BBC3 \| CTD_human 10672 \| GNA13 \| CTD_human
Inferring Gene	(Waiting for update.)
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:224) 25 \| ABL1 \| 1.916 \| DISEASES 55966 \| AJAP1 \| 1.073 \| DISEASES 238 \| ALK \| 1.824 \| DISEASES 84334 \| APOPT1 \| 1.253 \| DISEASES 10564 \| ARFGEF2 \| 1.202 \| DISEASES 8289 \| ARID1A \| 1.45 \| DISEASES 64225 \| ATL2 \| 1.159 \| DISEASES 545 \| ATR \| 1.18 \| DISEASES 9212 \| AURKB \| 1.073 \| DISEASES 567 \| B2M \| 2.259 \| DISEASES 586 \| BCAT1 \| 1.623 \| DISEASES 10018 \| BCL2L11 \| 3.382 \| DISEASES 605 \| BCL7A \| 2.288 \| DISEASES 641 \| BLM \| 1.975 \| DISEASES 55589 \| BMP2K \| 1.142 \| DISEASES 79866 \| BORA \| 1.173 \| DISEASES 79680 \| C22orf29 \| 2.88 \| DISEASES 23705 \| CADM1 \| 1.051 \| DISEASES 841 \| CASP8 \| 2.19 \| DISEASES 842 \| CASP9 \| 2.015 \| DISEASES 153733 \| CCDC112 \| 2.864 \| DISEASES 896 \| CCND3 \| 3.239 \| DISEASES 899 \| CCNF \| 1.102 \| DISEASES 10693 \| CCT6B \| 2.308 \| DISEASES 930 \| CD19 \| 4.216 \| DISEASES 914 \| CD2 \| 1.771 \| DISEASES 951 \| CD37 \| 2.515 \| DISEASES 958 \| CD40 \| 4.317 \| DISEASES 959 \| CD40LG \| 4.174 \| DISEASES 960 \| CD44 \| 2.533 \| DISEASES 962 \| CD48 \| 1.035 \| DISEASES 921 \| CD5 \| 3.133 \| DISEASES 1043 \| CD52 \| 2.572 \| DISEASES 965 \| CD58 \| 4.257 \| DISEASES 966 \| CD59 \| 1.915 \| DISEASES 974 \| CD79B \| 1.832 \| DISEASES 983 \| CDK1 \| 1.672 \| DISEASES 1029 \| CDKN2A \| 2.488 \| DISEASES 1122 \| CHML \| 1.094 \| DISEASES 26586 \| CKAP2 \| 1.569 \| DISEASES 1378 \| CR1 \| 1.979 \| DISEASES 1380 \| CR2 \| 3.698 \| DISEASES 1385 \| CREB1 \| 1.06 \| DISEASES 5476 \| CTSA \| 1.1 \| DISEASES 7852 \| CXCR4 \| 1.688 \| DISEASES 80319 \| CXXC4 \| 1.389 \| DISEASES 51428 \| DDX41 \| 1.08 \| DISEASES 23586 \| DDX58 \| 2.091 \| DISEASES 55070 \| DET1 \| 2.119 \| DISEASES 10301 \| DLEU1 \| 1.008 \| DISEASES 1755 \| DMBT1 \| 1.118 \| DISEASES 1785 \| DNM2 \| 1.098 \| DISEASES 1791 \| DNTT \| 2.952 \| DISEASES 1847 \| DUSP5 \| 3.018 \| DISEASES 1946 \| EFNA5 \| 2.19 \| DISEASES 1978 \| EIF4EBP1 \| 1.35 \| DISEASES 129080 \| EMID1 \| 2.516 \| DISEASES 953 \| ENTPD1 \| 3.378 \| DISEASES 3266 \| ERAS \| 1.124 \| DISEASES 51513 \| ETV7 \| 1.389 \| DISEASES 355 \| FAS \| 3.219 \| DISEASES 356 \| FASLG \| 1.936 \| DISEASES 83416 \| FCRL5 \| 1.125 \| DISEASES 8823 \| FGF16 \| 1.225 \| DISEASES 2268 \| FGR \| 3.356 \| DISEASES 2272 \| FHIT \| 1.148 \| DISEASES 752 \| FMNL1 \| 1.161 \| DISEASES 91010 \| FMNL3 \| 1.57 \| DISEASES 2526 \| FUT4 \| 1.485 \| DISEASES 2534 \| FYN \| 1.265 \| DISEASES 257144 \| GCSAM \| 2.787 \| DISEASES 2737 \| GLI3 \| 1.12 \| DISEASES 10672 \| GNA13 \| 3.546 \| DISEASES 1880 \| GPR183 \| 1.196 \| DISEASES 3005 \| H1F0 \| 1.107 \| DISEASES 9709 \| HERPUD1 \| 1.946 \| DISEASES 3006 \| HIST1H1C \| 1.659 \| DISEASES 3010 \| HIST1H1T \| 1.727 \| DISEASES 8359 \| HIST1H4A \| 1.11 \| DISEASES 8366 \| HIST1H4B \| 1.11 \| DISEASES 8364 \| HIST1H4C \| 1.11 \| DISEASES 8360 \| HIST1H4D \| 1.109 \| DISEASES 8367 \| HIST1H4E \| 1.11 \| DISEASES 8361 \| HIST1H4F \| 1.11 \| DISEASES 8294 \| HIST1H4I \| 1.11 \| DISEASES 8363 \| HIST1H4J \| 1.11 \| DISEASES 8362 \| HIST1H4K \| 1.11 \| DISEASES 8368 \| HIST1H4L \| 1.11 \| DISEASES 8370 \| HIST2H4A \| 1.11 \| DISEASES 554313 \| HIST2H4B \| 1.11 \| DISEASES 121504 \| HIST4H4 \| 1.11 \| DISEASES 3105 \| HLA-A \| 2.149 \| DISEASES 3106 \| HLA-B \| 1.095 \| DISEASES 3108 \| HLA-DMA \| 1.257 \| DISEASES 3150 \| HMGN1 \| 1.891 \| DISEASES 3151 \| HMGN2 \| 1.265 \| DISEASES 57594 \| HOMEZ \| 2.341 \| DISEASES 9653 \| HS2ST1 \| 1.556 \| DISEASES 219844 \| HYLS1 \| 2.8 \| DISEASES 3384 \| ICAM2 \| 1.64 \| DISEASES 3399 \| ID3 \| 3.957 \| DISEASES 3456 \| IFNB1 \| 2.14 \| DISEASES 100423062 \| IGLL5 \| 2.945 \| DISEASES 10320 \| IKZF1 \| 1.045 \| DISEASES 3586 \| IL10 \| 2.717 \| DISEASES 3559 \| IL2RA \| 1.035 \| DISEASES 3570 \| IL6R \| 1.584 \| DISEASES 10989 \| IMMT \| 1.095 \| DISEASES 3660 \| IRF2 \| 1.818 \| DISEASES 3662 \| IRF4 \| 3.097 \| DISEASES 3665 \| IRF7 \| 1.749 \| DISEASES 3683 \| ITGAL \| 2.668 \| DISEASES 3716 \| JAK1 \| 1.618 \| DISEASES 3725 \| JUN \| 1.202 \| DISEASES 3963 \| LGALS7 \| 1.645 \| DISEASES 4033 \| LRMP \| 1.382 \| DISEASES 4049 \| LTA \| 1.384 \| DISEASES 4067 \| LYN \| 2.763 \| DISEASES 7786 \| MAP3K12 \| 1.018 \| DISEASES 5599 \| MAPK8 \| 1.227 \| DISEASES 4153 \| MBL2 \| 1.128 \| DISEASES 4170 \| MCL1 \| 2.318 \| DISEASES 4193 \| MDM2 \| 2.233 \| DISEASES 4194 \| MDM4 \| 1.382 \| DISEASES 114614 \| MIR155HG \| 2.223 \| DISEASES 407975 \| MIR17HG \| 2.503 \| DISEASES 83881 \| MIXL1 \| 1.126 \| DISEASES 4311 \| MME \| 4.996 \| DISEASES 4332 \| MNDA \| 1.816 \| DISEASES 9242 \| MSC \| 1.87 \| DISEASES 4519 \| MT-CYB \| 1.04 \| DISEASES 10797 \| MTHFD2 \| 1.157 \| DISEASES 10903 \| MTMR11 \| 1.739 \| DISEASES 4602 \| MYB \| 1.733 \| DISEASES 4603 \| MYBL1 \| 2.825 \| DISEASES 4609 \| MYC \| 7.097 \| DISEASES 4615 \| MYD88 \| 1.284 \| DISEASES 4675 \| NAP1L3 \| 2.086 \| DISEASES 25915 \| NDUFAF3 \| 1.217 \| DISEASES 4753 \| NELL2 \| 1.322 \| DISEASES 4773 \| NFATC2 \| 1.056 \| DISEASES 11188 \| NISCH \| 1.498 \| DISEASES 10528 \| NOP56 \| 1.149 \| DISEASES 8131 \| NPRL3 \| 1.595 \| DISEASES 8650 \| NUMB \| 1.601 \| DISEASES 120406 \| NXPE2 \| 2.885 \| DISEASES 54827 \| NXPE4 \| 2.502 \| DISEASES 56957 \| OTUD7B \| 1.543 \| DISEASES 286530 \| P2RY8 \| 1.062 \| DISEASES 283208 \| P4HA3 \| 2.027 \| DISEASES 5049 \| PAFAH1B2 \| 1.727 \| DISEASES 142 \| PARP1 \| 2.504 \| DISEASES 5079 \| PAX5 \| 3.312 \| DISEASES 56146 \| PCDHA2 \| 2.688 \| DISEASES 5155 \| PDGFB \| 1.158 \| DISEASES 9260 \| PDLIM7 \| 3.964 \| DISEASES 57162 \| PELI1 \| 1.502 \| DISEASES 84992 \| PIGY \| 1.039 \| DISEASES 118788 \| PIK3AP1 \| 1.909 \| DISEASES 5292 \| PIM1 \| 1.368 \| DISEASES 11040 \| PIM2 \| 1.147 \| DISEASES 84812 \| PLCD4 \| 1.956 \| DISEASES 5336 \| PLCG2 \| 1.521 \| DISEASES 5366 \| PMAIP1 \| 1.607 \| DISEASES 5452 \| POU2F2 \| 1.203 \| DISEASES 639 \| PRDM1 \| 3.136 \| DISEASES 55660 \| PRPF40A \| 1.196 \| DISEASES 25766 \| PRPF40B \| 1.888 \| DISEASES 23215 \| PRRC2C \| 2.267 \| DISEASES 5699 \| PSMB10 \| 2.128 \| DISEASES 5696 \| PSMB8 \| 1.884 \| DISEASES 5698 \| PSMB9 \| 2.667 \| DISEASES 5788 \| PTPRC \| 2.645 \| DISEASES 5820 \| PVT1 \| 3.113 \| DISEASES 5866 \| RAB3IL1 \| 1.829 \| DISEASES 5902 \| RANBP1 \| 1.059 \| DISEASES 5905 \| RANGAP1 \| 1.141 \| DISEASES 5933 \| RBL1 \| 1.823 \| DISEASES 3516 \| RBPJ \| 3.421 \| DISEASES 5970 \| RELA \| 1.142 \| DISEASES 58480 \| RHOU \| 1.155 \| DISEASES 27246 \| RNF115 \| 1.241 \| DISEASES 6135 \| RPL11 \| 1.587 \| DISEASES 6146 \| RPL22 \| 1.761 \| DISEASES 6158 \| RPL28 \| 1.256 \| DISEASES 6194 \| RPS6 \| 1.242 \| DISEASES 27164 \| SALL3 \| 1.556 \| DISEASES 29843 \| SENP1 \| 1.449 \| DISEASES 327657 \| SERPINA9 \| 2.768 \| DISEASES 4068 \| SH2D1A \| 4.393 \| DISEASES 8631 \| SKAP1 \| 1.537 \| DISEASES 9123 \| SLC16A3 \| 1.208 \| DISEASES 347734 \| SLC35B2 \| 3.055 \| DISEASES 51000 \| SLC35B3 \| 1.987 \| DISEASES 6597 \| SMARCA4 \| 1.928 \| DISEASES 23583 \| SMUG1 \| 2.187 \| DISEASES 6622 \| SNCA \| 1.562 \| DISEASES 22986 \| SORCS3 \| 1.53 \| DISEASES 6664 \| SOX11 \| 2.914 \| DISEASES 6693 \| SPN \| 3.413 \| DISEASES 6714 \| SRC \| 1.19 \| DISEASES 6772 \| STAT1 \| 1.207 \| DISEASES 65975 \| STK33 \| 1.514 \| DISEASES 6850 \| SYK \| 1.965 \| DISEASES 84897 \| TBRG1 \| 1.519 \| DISEASES 7062 \| TCHH \| 1.465 \| DISEASES 7037 \| TFRC \| 1.966 \| DISEASES 55623 \| THUMPD1 \| 1.193 \| DISEASES 54106 \| TLR9 \| 1.551 \| DISEASES 121256 \| TMEM132D \| 1.629 \| DISEASES 7124 \| TNF \| 1.951 \| DISEASES 10673 \| TNFSF13B \| 2.101 \| DISEASES 7174 \| TPP2 \| 3.117 \| DISEASES 8717 \| TRADD \| 1.729 \| DISEASES 7185 \| TRAF1 \| 1.469 \| DISEASES 7106 \| TSPAN4 \| 1.534 \| DISEASES 10383 \| TUBB4B \| 1.27 \| DISEASES 7441 \| VPREB1 \| 1.199 \| DISEASES 331 \| XIAP \| 1.661 \| DISEASES 10773 \| ZBTB6 \| 2.075 \| DISEASES 340152 \| ZC3H12D \| 2.792 \| DISEASES 84186 \| ZCCHC7 \| 1.379 \| DISEASES 653082 \| ZDHHC11B \| 2.612 \| DISEASES 151126 \| ZNF385B \| 1.779 \| DISEASES
Locus	Symbol \| Locus(Total Locus:1) MYC \| 8q24.21

Disease ID	297
Disease	burkitt lymphoma
Integrated Phenotype	HPO \| Name(Total Integrated Phenotypes:13) HP:0000137 \| Abnormality of the ovary HP:0002239 \| Gastrointestinal hemorrhage HP:0100649 \| Neoplasm of the oral cavity HP:0005561 \| Abnormality of bone marrow cell morphology HP:0045040 \| Abnormal lactate dehydrogenase activity HP:0002027 \| Abdominal pain HP:0002017 \| Nausea and vomiting HP:0001732 \| Abnormality of the pancreas HP:0001392 \| Abnormality of the liver HP:0002733 \| Abnormality of the lymph nodes HP:0002149 \| Hyperuricemia HP:0001743 \| Abnormality of the spleen HP:0005214 \| Intestinal obstruction
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:40) HP:0002664 \| Neoplasia \| 10 HP:0002665 \| Lymphoma \| 5 HP:0002721 \| Immunodeficiency \| 4 HP:0012191 \| B-cell lymphoma \| 3 HP:0003002 \| Breast carcinoma \| 2 HP:0001909 \| Leukemia \| 2 HP:0002576 \| Intussusception \| 2 HP:0002885 \| Medulloblastoma \| 1 HP:0001919 \| Acute renal failure \| 1 HP:0001824 \| Weight loss \| 1 HP:0000789 \| Infertility \| 1 HP:0001658 \| Myocardial infarction \| 1 HP:0012125 \| Prostate cancer \| 1 HP:0003401 \| Paresthesia \| 1 HP:0012115 \| Liver inflammation \| 1 HP:0000867 \| Secondary hyperparathyroidism \| 1 HP:0001410 \| Decreased liver function \| 1 HP:0012539 \| Non-Hodgkin lymphoma \| 1 HP:0001394 \| Hepatic cirrhosis \| 1 HP:0001399 \| Liver failure \| 1 HP:0006554 \| Acute hepatic failure \| 1 HP:0004395 \| Malnutrition \| 1 HP:0007868 \| ARMD \| 1 HP:0005387 \| Combined immunodeficiency \| 1 HP:0100661 \| Trigeminal neuralgia \| 1 HP:0000670 \| Dental caries \| 1 HP:0012189 \| Hodgkin disease \| 1 HP:0001061 \| Acne \| 1 HP:0003193 \| Allergic rhinitis \| 1 HP:0012324 \| Myeloid leukemia \| 1 HP:0003251 \| Male infertility \| 1 HP:0002653 \| Bone pain \| 1 HP:0000083 \| Renal insufficiency \| 1 HP:0004808 \| Acute myelogenous leukemia \| 1 HP:0002027 \| Abdominal pain \| 1 HP:0002488 \| Acute leukemias \| 1 HP:0012531 \| Pain \| 1 HP:0012384 \| Nasal inflammation \| 1 HP:0000843 \| Hyperparathyroidism \| 1 HP:0001735 \| Acute pancreatitis \| 1

Disease ID	297
Disease	burkitt lymphoma
Manually Symptom	UMLS \| Name(Total Manually Symptoms:8) C2707258 \| infections C1997158 \| acute renal failure due to obstruction C1608408 \| malignant transformation C0598766 \| lymphomagenesis C0311284 \| multicentric reticulohistiocytosis C0085669 \| acute leukemia C0033626 \| protein deficiency C0022660 \| acute renal failure
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:6) C0009450 \| infection \| 2 C0149678 \| epstein-barr virus infection \| 1 C0022660 \| acute renal failure \| 1 C0024530 \| malaria \| 1 C1608408 \| malignant transformation \| 1 C0041364 \| tumor lysis syndrome \| 1

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

Text Mining Genotype(Total Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:4)
snpId	pubmedId	geneId	geneSymbol	diseaseId	sourceId	sentence	score	Year	geneSymbol_dbSNP	CHROMOSOME	POS	REF	ALT
rs121918683	NA	4609	MYC	umls:C0006413	CLINVAR	NA	0.495996478	NA	MYC	8	127738519	A	C
rs121918684	NA	4609	MYC	umls:C0006413	CLINVAR	NA	0.495996478	NA	MYC	8	127738379	G	C
rs121918685	NA	4609	MYC	umls:C0006413	CLINVAR	NA	0.495996478	NA	MYC	8	127738437	C	G
rs28933407	NA	4609	MYC	umls:C0006413	CLINVAR	NA	0.495996478	NA	MYC	8	127738431	C	T

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)

Mapped by lexical matching(Total Items:8)
HP ID	HP Name	MP ID	MP Name	Annotation
HP:0001743	Abnormality of the spleen	MP:0004485	increased response of heart to induced stress	increase in severity of the physiological response of the heart to induced stress such as cardiac hypertrophy due to mechanical pressure overload from aortic banding
HP:0002239	Gastrointestinal hemorrhage	MP:0012305	umbilical cord hemorrhage	bleeding into or from the umbilical cord
HP:0001732	Abnormality of the pancreas	MP:0014230	dilated crypts of Lieberkuhn
HP:0001392	Abnormality of the liver	MP:0020010	decreased bone mineral density of femur	reduction in the quatitative measurment value of mineral content of bone in the long bone of the thigh
HP:0005561	Abnormality of bone marrow cell morphology	MP:0013283	failure of ventral body wall closure	failure of the lateral body wall folds (a combination of mesoderm and ectoderm arising on each side of the embryo) to progress ventrally and meet in the midline and/or fuse to close the ventral body wall; normally, this closure is aided by growth of the h
HP:0005214	Intestinal obstruction	MP:0003587	ureter obstruction	a partial or total blockage in any part of the ureter causing obstruction of urine flow from the kidney to the urinary bladder; may be congenital, acquired, unilateral, bilateral, acute or chronic
HP:0002017	Nausea and vomiting	MP:0010426	abnormal heart and great artery attachment	any anomaly in the in the position or pattern of the connection site of the heart to any of the great arteries, including the pulmonary artery and aorta
HP:0002733	Abnormality of the lymph nodes	MP:0008024	absent lymph nodes	absence of the oval or bean shaped bodies located along the lymphatic system that consist of densely packed lymphocytes, lymph fluid and connective tissue; these are the sites where acquired immune responses are launched

Mapped by homologous gene(Total Items:10)
HP ID	HP Name	MP ID	MP Name	Annotation
HP:0005214	Intestinal obstruction	MP:0020321	increased vascular endothelial cell apoptosis	increase in the timing or the number of vascular endothelial cells undergoing programmed cell death
HP:0002149	Hyperuricemia	MP:0020316	decreased vascular endothelial cell proliferation	decrease in the expansion rate of any vascular endothelial cell population by cell division
HP:0001743	Abnormality of the spleen	MP:0013696	increased granulocyte monocyte progenitor cell number	increase in the number of a hematopoietic progenitor cell that is committed to the granulocyte and monocyte lineages; these cells are CD123-positive, and do not express Gata1 or Gata2 but do express C/EBPa, and Pu.1
HP:0002027	Abdominal pain	MP:0020220	decreased tear production	decreased production of the amount of fluid produced in the eye
HP:0001392	Abnormality of the liver	MP:0020169	increased thyroid gland weight	higher than average weight of the thyroid gland
HP:0002733	Abnormality of the lymph nodes	MP:0020154	impaired humoral immune response	impaired response of the immune system that mediates secreted antibodies produced in B cells
HP:0002239	Gastrointestinal hemorrhage	MP:0020215	impaired blood coagulation	impaired ability of the blood to clot
HP:0002017	Nausea and vomiting	MP:0020220	decreased tear production	decreased production of the amount of fluid produced in the eye
HP:0005561	Abnormality of bone marrow cell morphology	MP:0014071	increased cardiac muscle glycogen level	greater than the normal concentration of a readily converted carbohydrate reserve in heart muscle
HP:0001732	Abnormality of the pancreas	MP:0014233	bile duct epithelium hyperplasia

Disease ID	297
Disease	burkitt lymphoma
Case	(Waiting for update.)

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