eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| bronchopulmonary dysplasia | ||||
| Disease ID | 411 |
|---|---|
| Disease | bronchopulmonary dysplasia |
| Definition | A chronic lung disease developed after OXYGEN INHALATION THERAPY or mechanical ventilation (VENTILATION, MECHANICAL) usually occurring in certain premature infants (INFANT, PREMATURE) or newborn infants with respiratory distress syndrome (RESPIRATORY DISTRESS SYNDROME, NEWBORN). Histologically, it is characterized by the unusual abnormalities of the bronchioles, such as METAPLASIA, decrease in alveolar number, and formation of CYSTS. |
| Synonym | bpd - bronchopulmonary dysplasia bronchopulm dysplasia bronchopulmonary dysplasia (bpd) bronchopulmonary dysplasia [disease/finding] bronchopulmonary dysplasia of newborn bronchopulmonary dysplasia of newborn (disorder) chronic lung disease of babies chronic lung disease of prematurity dysplasia, bronchopulmonary perinatal bronchopulmonary dysplasia ventilator lung in newborn |
| Orphanet | |
| DOID | |
| UMLS | C0006287 |
| MeSH | |
| SNOMED-CT | |
| Comorbidity | UMLS | Disease | Sentences' Count(Total Sentences:23) C0020538 | hypertension | 11 C0020542 | pulmonary hypertension | 9 C0035309 | retinopathy | 2 C1619734 | pulmonary arterial hypertension | 2 C0032326 | pneumothorax | 2 C0042373 | vascular disease | 2 C1704437 | respiratory distress syndrome | 2 C0008495 | chorioamnionitis | 2 C0023529 | periventricular leukomalacia | 2 C0520459 | necrotizing enterocolitis | 1 C0019114 | hemosiderosis | 1 C0032285 | pneumonia | 1 C0022116 | ischemia | 1 C0158940 | transient tachypnea of the newborn | 1 C0004096 | asthma | 1 C0018799 | heart disease | 1 C0032285 | pneumonitis | 1 C0032914 | preeclampsia | 1 C0013990 | emphysema | 1 C0152021 | congenital heart disease | 1 C0024115 | lung disease | 1 C0020807 | pulmonary hemosiderosis | 1 C0019284 | diaphragmatic hernia | 1 |
| Curated Gene | Entrez_id | Symbol | Resource(Total Genes:5) |
| Inferring Gene | Entrez_id | Symbol | Resource(Total Genes:19) 1636 | ACE | CIPHER 1605 | DAG1 | CIPHER 3586 | IL10 | CIPHER 3565 | IL4 | CIPHER 4323 | MMP14 | CIPHER 4325 | MMP16 | CIPHER 4313 | MMP2 | CIPHER 5328 | PLAU | CIPHER 5054 | SERPINE1 | CIPHER 653509 | SFTPA1 | CIPHER 729238 | SFTPA2 | CIPHER 6439 | SFTPB | CIPHER 6440 | SFTPC | CIPHER 6441 | SFTPD | CIPHER 6890 | TAP1 | CIPHER 7124 | TNF | CIPHER 3553 | IL1B | CTD_human 7295 | TXN | CTD_human 10631 | POSTN | CTD_human |
| Text Mined Gene | (Waiting for update.) |
| Locus | (Waiting for update.) |
| Disease ID | 411 |
|---|---|
| Disease | bronchopulmonary dysplasia |
| Manually Symptom | UMLS | Name(Total Manually Symptoms:19) C2707258 | infections C2364133 | infection C2240374 | eosinophilia C1963220 | pulmonary hypertension C1963158 | left ventricular diastolic dysfunction C1370824 | interstitial emphysema C1145670 | respiratory failure C1000483 | anemia C0878787 | growth failure C0746102 | chronic lung disease C0425045 | sudden infant death C0276447 | rhinovirus infection C0242706 | hyperoxia C0232305 | right ventricular hypertrophy C0085680 | hypochloremia C0032285 | lung inflammation C0024899 | mast cell hyperplasia C0020440 | hypercarbia C0008677 | chronic bronchitis |
| Text Mined Symptom | UMLS | Name | Sentences' Count(Total Symptoms:5) C0020542 | pulmonary hypertension | 9 C0009450 | infection | 3 C0746102 | chronic lung disease | 1 C1370824 | interstitial emphysema | 1 C0242706 | hyperoxia | 1 |
Manually Genotype(Total Text Mining Genotypes:0) |
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| (Waiting for update.) |
Text Mining Genotype(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
All Snps(Total Genotypes:21) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| snpId | pubmedId | geneId | geneSymbol | diseaseId | sourceId | sentence | score | Year | geneSymbol_dbSNP | CHROMOSOME | POS | REF | ALT |
| rs10994336 | 24914473 | 288 | ANK3 | umls:C0006287 | BeFree | Following stratification by ethnicity, variants of the ANK3 gene (rs1938516 and rs10994336) were found to be associated with BPD in Malays (P-value=0.001 and 0.006, respectively). | 0.001085767 | 2014 | ANK3 | 10 | 60420054 | C | T |
| rs165599 | 17547583 | 1312 | COMT | umls:C0006287 | BeFree | These data suggest that COMT genetic variation at SNP rs165599 is associated with BPD I and influences prefrontal aspects of verbal memory in bipolar patients and healthy controls. | 0.001628651 | 2007 | ARVCF;COMT | 22 | 19969258 | G | A |
| rs1938516 | 24914473 | 288 | ANK3 | umls:C0006287 | BeFree | Following stratification by ethnicity, variants of the ANK3 gene (rs1938516 and rs10994336) were found to be associated with BPD in Malays (P-value=0.001 and 0.006, respectively). | 0.001085767 | 2014 | NA | 1 | 187433789 | T | A |
| rs2070744 | 25320160 | 342977 | NANOS3 | umls:C0006287 | BeFree | We could replicate and extend previous findings showing altered NOx (-) levels in BPD and an influence of NOS3 rs2070744 on NOS3 expression and NOx (-) concentration. | 0.000271442 | 2015 | NOS3 | 7 | 150992991 | C | T |
| rs2229569 | 17726703 | 6402 | SELL | umls:C0006287 | BeFree | Indeed, carrier states of genetic variants of cytokines (IFNgamma T+874A), adhesion molecules (L-selectin-Pro213Ser), elements of renin-angiotensin system (ACE-I/D), antioxidant enzymes (GST-P1 Val105Ile), and surfactant proteins (SPA1, SPB intron 4) has been identified as risk factors to BPD. | 0.000542884 | 2007 | SELL | 1 | 169704697 | G | T,A |
| rs2229569 | 17726703 | 653509 | SFTPA1 | umls:C0006287 | BeFree | Indeed, carrier states of genetic variants of cytokines (IFNgamma T+874A), adhesion molecules (L-selectin-Pro213Ser), elements of renin-angiotensin system (ACE-I/D), antioxidant enzymes (GST-P1 Val105Ile), and surfactant proteins (SPA1, SPB intron 4) has been identified as risk factors to BPD. | 0.001085767 | 2007 | SELL | 1 | 169704697 | G | T,A |
| rs2229569 | 17726703 | 1636 | ACE | umls:C0006287 | BeFree | Indeed, carrier states of genetic variants of cytokines (IFNgamma T+874A), adhesion molecules (L-selectin-Pro213Ser), elements of renin-angiotensin system (ACE-I/D), antioxidant enzymes (GST-P1 Val105Ile), and surfactant proteins (SPA1, SPB intron 4) has been identified as risk factors to BPD. | 0.009358507 | 2007 | SELL | 1 | 169704697 | G | T,A |
| rs2230912 | 23602648 | 11201 | POLI | umls:C0006287 | BeFree | After correction for multiple testing, the association between rs2230912 and HADS-depression score remained significant in the BPD group (p<0.006); this genetic effect explained 9% of the variance (partial η(2)=0.09). | 0.000542884 | 2013 | P2RX7;LOC105370032 | 12 | 121184393 | A | G |
| rs28364997 | 25331903 | 6531 | SLC6A3 | umls:C0006287 | BeFree | Recently, we identified a rare, nonsynonymous Slc6a3 variant that produces the DAT substitution Ala559Val in two male siblings who share a diagnosis of attention-deficit hyperactivity disorder (ADHD), with other studies identifying the variant in subjects with bipolar disorder (BPD) and autism spectrum disorder (ASD). | 0.000542884 | 2015 | SLC6A3 | 5 | 1403013 | G | A |
| rs34957318 | 23775869 | 6440 | SFTPC | umls:C0006287 | BeFree | We present an infant who was born premature at 23 weeks gestation with bronchopulmonary dysplasia and a SFTPC gene mutation, p.R167Q, who had a complicated neonatal course requiring 4 months of mechanical ventilation. | 0.007915422 | 2013 | BMP1;SFTPC | 8 | 22163947 | G | A |
| rs371131106 | 17726703 | 6402 | SELL | umls:C0006287 | BeFree | Indeed, carrier states of genetic variants of cytokines (IFNgamma T+874A), adhesion molecules (L-selectin-Pro213Ser), elements of renin-angiotensin system (ACE-I/D), antioxidant enzymes (GST-P1 Val105Ile), and surfactant proteins (SPA1, SPB intron 4) has been identified as risk factors to BPD. | 0.000542884 | 2007 | ACE | 17 | 63485346 | A | G |
| rs371131106 | 17726703 | 1636 | ACE | umls:C0006287 | BeFree | Indeed, carrier states of genetic variants of cytokines (IFNgamma T+874A), adhesion molecules (L-selectin-Pro213Ser), elements of renin-angiotensin system (ACE-I/D), antioxidant enzymes (GST-P1 Val105Ile), and surfactant proteins (SPA1, SPB intron 4) has been identified as risk factors to BPD. | 0.009358507 | 2007 | ACE | 17 | 63485346 | A | G |
| rs371131106 | 17726703 | 653509 | SFTPA1 | umls:C0006287 | BeFree | Indeed, carrier states of genetic variants of cytokines (IFNgamma T+874A), adhesion molecules (L-selectin-Pro213Ser), elements of renin-angiotensin system (ACE-I/D), antioxidant enzymes (GST-P1 Val105Ile), and surfactant proteins (SPA1, SPB intron 4) has been identified as risk factors to BPD. | 0.001085767 | 2007 | ACE | 17 | 63485346 | A | G |
| rs386602118 | 18242852 | 627 | BDNF | umls:C0006287 | BeFree | The study demonstrates that the BDNF C-270T and Val66Met polymorphisms are unlikely to contribute to the genetic predisposition to BPD as a whole. | 0.002442977 | 2008 | NA | NA | NA | NA | NA |
| rs386602276 | 24962835 | 3356 | HTR2A | umls:C0006287 | BeFree | A number of studies have assessed a relationship between the T102C polymorphism in the HTR2A gene with an increased risk of major depressive disorder (MDD), bipolar disorder (BPD), and schizophrenia (SCZ). | 0.000542884 | 2014 | NA | NA | NA | NA | NA |
| rs41084 | 19264272 | 497258 | BDNF-AS | umls:C0006287 | BeFree | Positive associations with pediatric BPD and the BDNF gene (Vall66), the GAD1 gene (4s2241165), and the dopamine transporter gene (rs41084) have been reported but none of these associations have been replicated in independent samples. | 0.000271442 | 2009 | SGCD | 5 | 156118554 | A | T |
| rs4500567 | 20052686 | 7103 | TSPAN8 | umls:C0006287 | BeFree | In the TSPAN8 upstream transcriptional control region however, we found rs4500567 to be associated with BPD. | 0.000271442 | 2010 | NA | 12 | 71166082 | G | C |
| rs556493 | 23897914 | 134957 | STXBP5 | umls:C0006287 | GWASCAT | A genome-wide association study (GWAS) for bronchopulmonary dysplasia. | 0.12 | 2013 | STXBP5 | 6 | 147228161 | A | G |
| rs6313 | 24962835 | 3356 | HTR2A | umls:C0006287 | BeFree | A number of studies have assessed a relationship between the T102C polymorphism in the HTR2A gene with an increased risk of major depressive disorder (MDD), bipolar disorder (BPD), and schizophrenia (SCZ). | 0.000542884 | 2014 | HTR2A | 13 | 46895805 | G | A |
| rs72791417 | 23897914 | 29119 | CTNNA3 | umls:C0006287 | GWASCAT | A genome-wide association study (GWAS) for bronchopulmonary dysplasia. | 0.12 | 2013 | CTNNA3 | 10 | 65983896 | A | T |
| rs956572 | 21167476 | 596 | BCL2 | umls:C0006287 | BeFree | Here, we examined the effects of the Bcl-2 gene single nucleotide polymorphism (SNP) rs956572 on intracellular Ca(2+) dynamics in patients with BPD. | 0.000271442 | 2011 | BCL2 | 18 | 63153338 | A | G |
GWASdb Annotation(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:73) | |||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CHR | POS | SNPID | REF | ALT | ORI_SNPID | PMID | P_VALUE | P_VALUE_TEXT | OR/BETA | CI95_TEXT | GWAS_INITIAL_SAMPLE_SIZE | SUB_POPULATION | SUPER_POPULATION | GWAS_TRAIT | HPO_ID | HPO_TERM | DO_ID | DO_TERM | MESH_ID | MESH_TERM | EFO_ID | EFO_TERM | DOLITE_TERM | RISK_ALLELE | PUBLICATION_TYPE | AA | GENE_SYMBOL | TYPE | REFGENE |
| 1 | 42297124 | rs349423 | C | T | rs349423 | 23897914 | 9.00E-06 | NA | 2.52 | [1.67-3.79] | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 1 | 243290642 | rs2105146 | G | A | rs55716084 | 23897914 | 3.00E-06 | Dominant model | 1.59 | NA | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 1 | 243290642 | rs2105146 | G | A | rs55716084 | 23897914 | 3.20E-06 | Dominant model | 1.59 | NA | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 1 | 243290642 | rs55716084 | G | A | rs55716084 | 23897914 | 3.00E-06 | Dominant model | 1.59 | NA | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 1 | 243290642 | rs55716084 | G | A | rs55716084 | 23897914 | 3.20E-06 | Dominant model | 1.59 | NA | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 1 | 243304012 | rs3753542 | T | C | rs3753542 | 23897914 | 9.70E-06 | Dominant model | 1.58 | NA | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 1 | 243309191 | rs4658538 | A | G | rs4658538 | 23897914 | 9.50E-06 | Dominant model | 1.58 | NA | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 2 | 12252350 | rs17551536 | A | G | rs17551536 | 23897914 | 5.00E-06 | NA | 1.47 | [0.58-0.80] | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 3 | 61127205 | rs9877396 | T | C | rs9877396 | 23897914 | 3.00E-06 | EA | 2 | NA | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 3 | 195596907 | rs2278034 | T | C | rs2278034 | 23897914 | 5.00E-06 | EA | 1.83 | NA | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 4 | 117875261 | rs1440306 | T | G | rs1440306 | 23897914 | 1.00E-06 | Dominant model | 1.37 | NA | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 4 | 117875261 | rs1440306 | T | G | rs1440306 | 23897914 | 1.30E-06 | Dominant model | 1.52 | NA | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 5 | 62384699 | rs71627250 | C | T | rs71627250 | 23897914 | 6.00E-06 | NA | 1.65 | [1.33-2.04] | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 5 | 120216037 | rs78975256 | T | C | rs78975256 | 23897914 | 4.00E-06 | NA | 2.44 | [0.28-0.60] | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 5 | 136902696 | rs1541364 | G | A | rs1541364 | 23897914 | 8.50E-06 | Dominant model | 1.51 | NA | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 5 | 136902696 | rs1541364 | G | A | rs1541364 | 23897914 | 9.00E-06 | Dominant model | 1.24 | NA | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 5 | 177922198 | rs118078182 | G | A | rs118078182 | 23897914 | 1.82E-04 | NA | 1.76 | [1.31-2.36] | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 5 | 179395326 | rs6884272 | C | A | rs74647022 | 23897914 | 7.07E-05 | NA | 1.27 | [1.13-1.43] | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 6 | 54054686 | rs6934690 | T | A | rs6934690 | 23897914 | 7.68E-06 | NA | 1.89 | [1.43-2.50] | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 6 | 147531081 | rs2786189 | G | T | rs2786189 | 23897914 | 5.00E-06 | Hispanic | 1.47 | NA | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 6 | 147535305 | rs1221638 | G | A | rs1221638 | 23897914 | 7.80E-06 | Hispanic | 1.46 | NA | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 6 | 147549297 | rs556493 | A | G | rs556493 | 23897914 | 1.00E-06 | NA | 1.35 | [0.66-0.84] | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 6 | 147639534 | rs9373522 | C | T | rs9373522 | 23897914 | 7.40E-06 | NA | 1.32 | NA | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 6 | 147670086 | rs12191720 | T | C | rs12191720 | 23897914 | 4.10E-06 | NA | 1.33 | NA | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 6 | 147713764 | rs7765526 | A | G | rs7765526 | 23897914 | 2.11E-06 | NA | 1.33 | [1.19-1.52] | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 7 | 1022728 | rs12701220 | T | C | rs12701220 | 23897914 | 3.00E-06 | Hispanic | 1.54 | NA | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 7 | 78152672 | rs62468577 | C | T | rs62468577 | 23897914 | 5.80E-06 | Dominant model | 1.61 | NA | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 7 | 78152672 | rs62468577 | C | T | rs62468577 | 23897914 | 6.00E-06 | Dominant model | 1.54 | NA | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 8 | 102596210 | rs6988306 | C | T | rs6988306 | 23897914 | 3.00E-06 | EA | 2.78 | NA | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 8 | 114873380 | rs1912816 | A | G | rs1912816 | 23897914 | 5.90E-06 | Dominant model | 1.47 | NA | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 8 | 114873380 | rs1912816 | A | G | rs1912816 | 23897914 | 6.00E-06 | Dominant model | 1.28 | NA | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 10 | 20368998 | rs4336923 | A | G | rs4336923 | 23897914 | 6.40E-06 | Hispanic | 1.48 | NA | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 10 | 20434780 | rs4634985 | T | C | rs4634985 | 23897914 | 3.00E-06 | Hispanic | 1.54 | NA | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 10 | 60285619 | rs12571250 | G | A | rs12571250 | 23897914 | 3.31E-05 | NA | 2.03 | [1.45-2.84] | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 10 | 67679568 | rs1941996 | G | T | rs1941996 | 23897914 | 3.30E-06 | Dominant model | 1.52 | NA | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 10 | 67706852 | rs10996785 | T | G | rs10996785 | 23897914 | 7.60E-06 | NA | 1.35 | NA | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 10 | 67707663 | rs1786933 | C | T | rs1786933 | 23897914 | 4.40E-06 | NA | 1.43 | NA | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 10 | 67721021 | rs1941988 | T | C | rs1941988 | 23897914 | 1.80E-06 | NA | 1.47 | NA | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 10 | 67727223 | rs1670137 | T | C | rs1670137 | 23897914 | 1.90E-06 | NA | 1.41 | NA | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 10 | 67729575 | rs3017064 | G | A | rs3017064 | 23897914 | 1.70E-06 | NA | 1.41 | NA | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 10 | 67743654 | rs72791417 | A | T | rs72791417 | 23897914 | 1.00E-06 | NA | 1.45 | [0.59-0.80] | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 10 | 67743819 | rs2212719 | A | G | rs2212719 | 23897914 | 7.90E-06 | NA | 1.35 | NA | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 10 | 67747744 | rs6480123 | G | A,C,T | rs6480123 | 23897914 | 4.70E-06 | NA | 1.41 | NA | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 10 | 67761720 | rs12356475 | T | C | rs12356475 | 23897914 | 1.54E-06 | NA | 1.43 | [1.23-1.64] | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 10 | 73729752 | rs4148913 | A | G | rs4148913 | 23897914 | 6.82E-05 | NA | 1.27 | [1.14-1.43] | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 10 | 73820001 | rs1049269 | A | G | rs1049269 | 21836138 | 4.40E-09 | Bronchopulmonary dysplasia | NA | NA | 21 European ancestry neonate cases; 75 European ancestry neonate controls; 21 African neonate cases; 86 African neonate controls | African(107) | European(96) | ALL(203) | AFR(107) | EUR(96) | ALL(203) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA | NA | NA | NA | Bronchopulmonary dysplasia | NA | Research Support, Non-U.S. Gov't |
| 10 | 73837420 | rs1245560 | A | C | rs1245560 | 21836138 | 1.66E-07 | Bronchopulmonary dysplasia | NA | NA | 21 European ancestry neonate cases; 75 European ancestry neonate controls; 21 African neonate cases; 86 African neonate controls | African(107) | European(96) | ALL(203) | AFR(107) | EUR(96) | ALL(203) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA | NA | NA | NA | Bronchopulmonary dysplasia | NA | Research Support, Non-U.S. Gov't |
| 11 | 35536622 | rs635366 | G | T | rs635366 | 23897914 | 3.40E-06 | Hispanic | 1.53 | NA | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 11 | 35539269 | rs650950 | T | C | rs650950 | 23897914 | 2.00E-06 | Hispanic | 1.55 | NA | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 11 | 38285501 | rs10836945 | T | C | rs10836945 | 23897914 | 7.90E-06 | AA | 2.17 | NA | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 11 | 38285501 | rs10836945 | T | C | rs10836945 | 23897914 | 8.00E-06 | AA | 2.17 | NA | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 11 | 104972518 | rs11226613 | T | A | rs11226613 | 23897914 | 5.00E-06 | NA | 1.43 | [0.60-0.81] | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 13 | 74433807 | rs4883955 | T | G | rs4883955 | 23897914 | 3.00E-06 | EA | 2 | NA | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 15 | 23078384 | rs7174119 | A | G | rs7174119 | 23897914 | 2.29E-04 | NA | 1.32 | [1.14-1.52] | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 15 | 35346541 | rs10162694 | C | A | rs10162694 | 23897914 | 9.00E-06 | Dominant model | 1.55 | NA | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 15 | 35346541 | rs10162694 | C | A | rs10162694 | 23897914 | 9.20E-06 | Dominant model | 1.66 | NA | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 15 | 69936082 | rs4777168 | A | G | rs4777168 | 23897914 | 1.75E-04 | NA | 1.27 | [1.11-1.41] | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 15 | 79463847 | rs1474256 | C | T | rs1474256 | 23897914 | 6.00E-06 | Dominant model | 1.2 | NA | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 15 | 79463847 | rs1474256 | C | T | rs1474256 | 23897914 | 6.30E-06 | Dominant model | 1.56 | NA | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 15 | 86854359 | rs10152333 | T | C | rs10152333 | 21836138 | 1.90E-07 | Bronchopulmonary dysplasia | NA | NA | 21 European ancestry neonate cases; 75 European ancestry neonate controls; 21 African neonate cases; 86 African neonate controls | African(107) | European(96) | ALL(203) | AFR(107) | EUR(96) | ALL(203) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA | NA | NA | NA | Bronchopulmonary dysplasia | NA | Research Support, Non-U.S. Gov't |
| 15 | 87536101 | rs1010419 | A | G | rs1010419 | 21836138 | 7.70E-09 | Bronchopulmonary dysplasia | NA | NA | 21 European ancestry neonate cases; 75 European ancestry neonate controls; 21 African neonate cases; 86 African neonate controls | African(107) | European(96) | ALL(203) | AFR(107) | EUR(96) | ALL(203) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA | NA | NA | NA | Bronchopulmonary dysplasia | NA | Research Support, Non-U.S. Gov't |
| 15 | 87539918 | rs2701405 | C | A | rs2701405 | 21836138 | 2.50E-08 | Bronchopulmonary dysplasia | NA | NA | 21 European ancestry neonate cases; 75 European ancestry neonate controls; 21 African neonate cases; 86 African neonate controls | African(107) | European(96) | ALL(203) | AFR(107) | EUR(96) | ALL(203) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA | NA | NA | NA | Bronchopulmonary dysplasia | NA | Research Support, Non-U.S. Gov't |
| 15 | 98744548 | rs2620860 | A | G | rs2620860 | 23897914 | 6.54E-04 | NA | 1.24 | [1.09-1.40] | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 18 | 24687371 | rs9953270 | T | C | rs9953270 | 23897914 | 3.00E-06 | NA | 1.33 | [0.66-0.85] | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 18 | 28639548 | rs1126214 | T | C | rs1126214 | 23897914 | 6.50E-06 | Dominant model | 1.54 | NA | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 18 | 28639548 | rs1126214 | T | C | rs1126214 | 23897914 | 7.00E-06 | Dominant model | 1.25 | NA | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 18 | 71071196 | rs4508503 | G | T | rs4508503 | 23897914 | 4.60E-05 | NA | 1.28 | NA | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 18 | 71078224 | rs8089528 | A | G | rs8089528 | 23897914 | 4.28E-05 | NA | 1.28 | [1.14-1.44] | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| 19 | 23056346 | rs7246967 | T | G | rs7246967 | 23897914 | 4.00E-06 | Dominant model | 1.54 | NA | 117 African American newborn cases; 108 African American newborn controls; 448 Hispanic newborn cases; 460 Hispanic newborn controls; 74 Asian or Pacific Islander newborn cases; 93 Asian or Pacific Islander newborn control; 174 European ancestry newborn cases; 216 European ancestry newborn controls; 14 newborn cases; 22 newborn controls | NOPOP(36) | European(390) | Asia,Pacific Islander(167) | African American(225) | Hispanic(908) | ALL(1726) | NOPOP(36) | HIS(908) | AFR(225) | EUR(390) | ASN,OCN(167) | ALL(1726) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA |
| X | 29526520 | rs6526874 | T | C | rs6526874 | 21836138 | 5.70E-08 | Bronchopulmonary dysplasia | NA | NA | 21 European ancestry neonate cases; 75 European ancestry neonate controls; 21 African neonate cases; 86 African neonate controls | African(107) | European(96) | ALL(203) | AFR(107) | EUR(96) | ALL(203) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA | NA | NA | NA | Bronchopulmonary dysplasia | NA | Research Support, Non-U.S. Gov't |
| X | 29631530 | rs4829242 | C | T | rs4829242 | 21836138 | 8.10E-08 | Bronchopulmonary dysplasia | NA | NA | 21 European ancestry neonate cases; 75 European ancestry neonate controls; 21 African neonate cases; 86 African neonate controls | African(107) | European(96) | ALL(203) | AFR(107) | EUR(96) | ALL(203) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA | NA | NA | NA | Bronchopulmonary dysplasia | NA | Research Support, Non-U.S. Gov't |
| X | 32071504 | rs7887541 | T | C | rs7887541 | 21836138 | 6.50E-13 | Bronchopulmonary dysplasia | NA | NA | 21 European ancestry neonate cases; 75 European ancestry neonate controls; 21 African neonate cases; 86 African neonate controls | African(107) | European(96) | ALL(203) | AFR(107) | EUR(96) | ALL(203) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA | NA | NA | NA | Bronchopulmonary dysplasia | NA | Research Support, Non-U.S. Gov't |
| X | 32349435 | rs5927969 | T | G | rs5927969 | 21836138 | 5.80E-13 | Bronchopulmonary dysplasia | NA | NA | 21 European ancestry neonate cases; 75 European ancestry neonate controls; 21 African neonate cases; 86 African neonate controls | African(107) | European(96) | ALL(203) | AFR(107) | EUR(96) | ALL(203) | Bronchopulmonary dysplasia | HPOID:0010960 | Bronchopulmonary sequestration | DOID:11650 | bronchopulmonary dysplasia | NA | NA | NA | NA | Bronchopulmonary dysplasia | NA | Research Support, Non-U.S. Gov't |
Mapped by lexical matching(Total Items:7) | ||||
|---|---|---|---|---|
| HP ID | HP Name | MP ID | MP Name | Annotation |
| HP:0001667 | Right ventricular hypertrophy | MP:0010420 | muscular ventricular septal defect | abnormal communications between the two lower chambers of the heart, involving the muscular septum and often occurring as multiple communications, and includes central muscular or midmuscular, apical, or marginal communications when the defect is along th |
| HP:0006528 | Chronic lung disease | MP:0010895 | increased lung compliance | increased ability of the lung to distend in response to pressure without disruption, usually expressed as the unit volume of change in the lung per unit of pressure |
| HP:0001708 | Right ventricular failure | MP:0010420 | muscular ventricular septal defect | abnormal communications between the two lower chambers of the heart, involving the muscular septum and often occurring as multiple communications, and includes central muscular or midmuscular, apical, or marginal communications when the defect is along th |
| HP:0002098 | Respiratory distress | MP:0001954 | respiratory distress | physical difficulty or inability to breathe; shortness of breath |
| HP:0001622 | Premature birth | MP:0009703 | decreased birth body size | reduction in average body size at birth compared to controls |
| HP:0001518 | Small for gestational age | MP:0011967 | increased or absent threshold for auditory brainstem response | increase in the value at which one or more sound frequencies or broadband clicks first elicits a recordable response generated by electrical activity of neurons in the ascending auditory system, or complete lack of a recordable response at any frequency o |
| HP:0006597 | Diaphragmatic paralysis | MP:0000755 | hindlimb paralysis | loss of power of voluntary movement in the muscles of the hindlimb through injury or disease of it or its nerve supply |
Mapped by homologous gene(Total Items:17) | ||||
|---|---|---|---|---|
| HP ID | HP Name | MP ID | MP Name | Annotation |
| HP:0002097 | Emphysema | MP:0020321 | increased vascular endothelial cell apoptosis | increase in the timing or the number of vascular endothelial cells undergoing programmed cell death |
| HP:0100750 | Atelectasis | MP:0020321 | increased vascular endothelial cell apoptosis | increase in the timing or the number of vascular endothelial cells undergoing programmed cell death |
| HP:0012735 | Cough | MP:0014185 | cerebellum atrophy | acquired diminution of the size of the cerebellum associated with wasting as from death and reabsorption of cells, diminished cellular proliferation, decreased cellular volume, pressure, ischemia, malnutrition, reduced function or malfunction, or hormonal |
| HP:0002094 | Dyspnea | MP:0014185 | cerebellum atrophy | acquired diminution of the size of the cerebellum associated with wasting as from death and reabsorption of cells, diminished cellular proliferation, decreased cellular volume, pressure, ischemia, malnutrition, reduced function or malfunction, or hormonal |
| HP:0001708 | Right ventricular failure | MP:0012250 | absent heart valves | failure to form all of the membranous folds of the heart that prevent reflux of fluid |
| HP:0001667 | Right ventricular hypertrophy | MP:0013241 | embryo tissue necrosis | morphological changes resulting from pathological death of some or all embryo tissue; usually due to irreversible damage |
| HP:0001622 | Premature birth | MP:0020254 | decreased collagen level | decreased level of the main structural protein of the various connective tissues in animals |
| HP:0002098 | Respiratory distress | MP:0014198 | absent pituitary infundibular stalk | absence of the apical portion of the tubular structure extending from the hypothalamus to the posterior lobe of the pituitary gland |
| HP:0002795 | Functional respiratory abnormality | MP:0011098 | embryonic lethality during organogenesis, complete penetrance | death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9-9.5 to less than E14) |
| HP:0004887 | Respiratory failure requiring assisted ventilation | MP:0011090 | perinatal lethality, incomplete penetrance | the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the perinatal period (Mus: E18.5 through postnatal day 1) |
| HP:0003546 | Exercise intolerance | MP:0020234 | decreased basal metabolism | decrease in heat production of an organism at the lowest level of cell chemistry in an inactive, awake, and fasting state |
| HP:0002871 | Central apnea | MP:0020039 | increased bone ossification | increase in the formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance |
| HP:0001518 | Small for gestational age | MP:0020254 | decreased collagen level | decreased level of the main structural protein of the various connective tissues in animals |
| HP:0006597 | Diaphragmatic paralysis | MP:0014074 | increased brain glycogen level | greater than the normal concentration of a readily converted carbohydrate reserve in brain |
| HP:0002786 | Tracheobronchomalacia | MP:0013292 | embryonic lethality prior to organogenesis | death prior to the completion of embryo turning (Mus: E9-9.5) |
| HP:0006528 | Chronic lung disease | MP:0020254 | decreased collagen level | decreased level of the main structural protein of the various connective tissues in animals |
| HP:0002360 | Sleep disturbance | MP:0020169 | increased thyroid gland weight | higher than average weight of the thyroid gland |
| Disease ID | 411 |
|---|---|
| Disease | bronchopulmonary dysplasia |
| Case | (Waiting for update.) |