eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| autoimmune hemolytic anemia | ||||
| Disease ID | 544 |
|---|---|
| Disease | autoimmune hemolytic anemia |
| Manually Symptom | UMLS | Name(Total Manually Symptoms:43) C2697391 | rheumatoid arthritis C2697310 | sarcoidosis C1963220 | pulmonary hypertension C1962966 | retinopathy C1956158 | ventricular septal perforation C1744558 | t cell deficiency C1112746 | primary hepatic lymphoma C1096584 | chlamydia pneumoniae infection C1000587 | pemphigus C0919267 | ovarian neoplasm C0876998 | intracardiac thrombus C0751340 | ocular myasthenia gravis C0740302 | 5q- syndrome C0349632 | splenic marginal zone lymphoma C0271072 | retinal phlebitis C0268379 | cholinesterase deficiency C0241910 | autoimmune hepatitis C0152025 | polyneuropathy C0086438 | hypogammaglobulinemia C0079744 | diffuse large cell lymphoma C0079744 | diffuse large b-cell lymphoma C0037116 | silicosis C0030809 | pemphigus vulgaris C0030186 | extramammary paget's disease C0027765 | neurologic disorders C0027697 | nephritis C0026946 | mycoses C0026896 | myasthenia gravis C0026764 | multiple myeloma C0024314 | lymphoproliferative disorders C0024305 | non-hodgkin's lymphoma C0024299 | malignant lymphoma C0024141 | systemic lupus erythematosus C0023434 | b cell lymphocytic leukemia C0023418 | leukemia C0020981 | angioimmunoblastic lymphadenopathy with dysproteinemia C0020550 | hyperthyroidism C0019080 | hemorrhage C0014059 | acute disseminated encephalomyelitis C0009324 | ulcerative colitis C0008313 | sclerosing cholangitis C0008312 | primary biliary cirrhosis C0002892 | pernicious anemia |
| Text Mined Symptom | UMLS | Name | Sentences' Count(Total Symptoms:9) C0023418 | leukemia | 3 C0026764 | multiple myeloma | 3 C0009324 | ulcerative colitis | 2 C0008313 | sclerosing cholangitis | 2 C0024141 | systemic lupus erythematosus | 2 C0349632 | splenic marginal zone lymphoma | 1 C0241910 | autoimmune hepatitis | 1 C0017531 | castleman's disease | 1 C0024314 | lymphoproliferative disorders | 1 |
Manually Genotype(Total Text Mining Genotypes:0) |
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| (Waiting for update.) |
Text Mining Genotype(Total Genotypes:0) | |
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| (Waiting for update.) | |
All Snps(Total Genotypes:0) | |
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| (Waiting for update.) | |
GWASdb Annotation(Total Genotypes:0) | |
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| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:0) | |
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| (Waiting for update.) | |
Mapped by lexical matching(Total Items:5) | ||||
|---|---|---|---|---|
| HP ID | HP Name | MP ID | MP Name | Annotation |
| HP:0001324 | Muscle weakness | MP:0000746 | weakness | state of being infirm or less strong than normal |
| HP:0001878 | Hemolytic anemia | MP:0008388 | hypochromic microcytic anemia | hemoglobin deficiency resulting from a reduction in the concentration of hemoglobin in red cells, where the erythrocyte corpuscular volume is smaller than normal |
| HP:0001939 | Abnormality of metabolism/homeostasis | MP:0020010 | decreased bone mineral density of femur | reduction in the quatitative measurment value of mineral content of bone in the long bone of the thigh |
| HP:0001890 | Autoimmune hemolytic anemia | MP:0001577 | anemia | less than normal levels of red blood cells and/or hemoglobin within red blood cells, or volume of packed red blood cells in the bloodstream, resulting in insufficient oxygenation of tissues and organs |
| HP:0001635 | Congestive heart failure | MP:0011925 | abnormal heart echocardiography feature | any anomaly in echocardiographic representation of systolic and diastolic function, ventricular compliance, valvular function, or interventricular septum features |
Mapped by homologous gene(Total Items:16) | ||||
|---|---|---|---|---|
| HP ID | HP Name | MP ID | MP Name | Annotation |
| HP:0001635 | Congestive heart failure | MP:0020329 | decreased capillary density | reduction in the number of capillaries in a given cross-sectional area of a tissue |
| HP:0002094 | Dyspnea | MP:0014185 | cerebellum atrophy | acquired diminution of the size of the cerebellum associated with wasting as from death and reabsorption of cells, diminished cellular proliferation, decreased cellular volume, pressure, ischemia, malnutrition, reduced function or malfunction, or hormonal |
| HP:0001945 | Fever | MP:0020254 | decreased collagen level | decreased level of the main structural protein of the various connective tissues in animals |
| HP:0002721 | Immunodeficiency | MP:0020316 | decreased vascular endothelial cell proliferation | decrease in the expansion rate of any vascular endothelial cell population by cell division |
| HP:0011675 | Arrhythmia | MP:0020309 | increased creatine kinase activity | increased ability of to catalyze the reaction: ATP + creatine = N-phosphocreatine + ADP + 2 H(+). |
| HP:0002960 | Autoimmunity | MP:0020220 | decreased tear production | decreased production of the amount of fluid produced in the eye |
| HP:0002315 | Headache | MP:0020137 | decreased bone mineralization | decrease in the rate at which minerals are deposited into bone |
| HP:0002027 | Abdominal pain | MP:0020220 | decreased tear production | decreased production of the amount of fluid produced in the eye |
| HP:0001939 | Abnormality of metabolism/homeostasis | MP:0020254 | decreased collagen level | decreased level of the main structural protein of the various connective tissues in animals |
| HP:0001878 | Hemolytic anemia | MP:0020154 | impaired humoral immune response | impaired response of the immune system that mediates secreted antibodies produced in B cells |
| HP:0002665 | Lymphoma | MP:0020154 | impaired humoral immune response | impaired response of the immune system that mediates secreted antibodies produced in B cells |
| HP:0000980 | Pallor | MP:0020186 | altered susceptibility to bacterial infection | a change in the likelihood that an organism will develop ill effects from a bacterial infection or from components of or toxins produced by bacteria |
| HP:0012378 | Fatigue | MP:0013659 | abnormal erythroid lineage cell morphology | any structural anomaly of an immature or mature cell in the lineage leading to and including erythrocytes |
| HP:0001324 | Muscle weakness | MP:0020309 | increased creatine kinase activity | increased ability of to catalyze the reaction: ATP + creatine = N-phosphocreatine + ADP + 2 H(+). |
| HP:0001744 | Splenomegaly | MP:0020254 | decreased collagen level | decreased level of the main structural protein of the various connective tissues in animals |
| HP:0001890 | Autoimmune hemolytic anemia | MP:0020154 | impaired humoral immune response | impaired response of the immune system that mediates secreted antibodies produced in B cells |
| Disease ID | 544 |
|---|---|
| Disease | autoimmune hemolytic anemia |
| Case | (Waiting for update.) |