eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| antisocial personality disorder | ||||
| Disease ID | 333 |
|---|---|
| Disease | antisocial personality disorder |
| Definition | A personality disorder whose essential feature is a pervasive pattern of disregard for, and violation of, the rights of others that begins in childhood or early adolescence and continues into adulthood. The individual must be at least age 18 and must have a history of some symptoms of CONDUCT DISORDER before age 15. (From DSM-IV, 1994) |
| Synonym | antisocial or sociopathic personality disorder antisocial personalities antisocial personality antisocial personality dis antisocial personality disorder (disorder) antisocial personality disorder [disease/finding] antisocial personality disorders asocial personality asp disorder disorder, antisocial personality disorders, antisocial personality dissocial personality disorder dissocial personality disorder (disorder) dyssocial personality personalities, antisocial personalities, psychopathic personalities, sociopathic personality dis antisocial personality disorder, antisocial personality disorders, antisocial personality, antisocial personality, psychopathic personality, sociopathic psychopath psychopath.personality psychopathic constitution psychopathic personalities psychopathic personality psychopathic personality disorder psychopaths psychopathy sociopath sociopathic personalities sociopathic personality sociopathic personality disorder sociopaths sociopathy |
| DOID | |
| ICD10 | |
| UMLS | C0003431 |
| MeSH | |
| SNOMED-CT | |
| Comorbidity | UMLS | Disease | Sentences' Count(Total Sentences:13) C0003467 | anxiety | 5 C0003469 | anxiety disorder | 3 C0006012 | borderline personality disorder | 2 C0041696 | major depressive disorder | 1 C0003469 | anxiety disorders | 1 C0027932 | psychoneurosis | 1 C0038358 | stomach ulcer | 1 C0030662 | pathological gambling | 1 C0001973 | alcoholism | 1 C0149654 | conduct disorder | 1 C0003431 | antisocial personality disorder | 1 C0036341 | schizophrenia | 1 C0031212 | personality disorders | 1 |
| Curated Gene | Entrez_id | Symbol | Resource(Total Genes:1) |
| Inferring Gene | Entrez_id | Symbol | Resource(Total Genes:6) |
| Text Mined Gene | Entrez_id | Symbol | Score | Resource(Total Genes:47) 84938 | ATG4C | 2.259 | DISEASES 551 | AVP | 1.104 | DISEASES 64115 | C10orf54 | 1.568 | DISEASES 1012 | CDH13 | 1.501 | DISEASES 84570 | COL25A1 | 3.272 | DISEASES 1312 | COMT | 1.554 | DISEASES 1325 | CORT | 2.437 | DISEASES 9244 | CRLF1 | 1.614 | DISEASES 1813 | DRD2 | 4.241 | DISEASES 1814 | DRD3 | 1.96 | DISEASES 2232 | FDXR | 2.385 | DISEASES 2316 | FLNA | 2.69 | DISEASES 2550 | GABBR1 | 2.301 | DISEASES 2555 | GABRA2 | 3.46 | DISEASES 2566 | GABRG2 | 2.896 | DISEASES 2618 | GART | 2.009 | DISEASES 2621 | GAS6 | 1.492 | DISEASES 2899 | GRIK3 | 2.966 | DISEASES 3351 | HTR1B | 3.48 | DISEASES 3356 | HTR2A | 3.076 | DISEASES 3363 | HTR7 | 1.819 | DISEASES 401260 | LINC00951 | 4.608 | DISEASES 57497 | LRFN2 | 3.779 | DISEASES 4128 | MAOA | 5.326 | DISEASES 4129 | MAOB | 1.629 | DISEASES 26151 | NAT9 | 1.562 | DISEASES 9241 | NOG | 1.19 | DISEASES 9520 | NPEPPS | 1.927 | DISEASES 4905 | NSF | 1.743 | DISEASES 4521 | NUDT1 | 1.846 | DISEASES 4988 | OPRM1 | 1.203 | DISEASES 5021 | OXTR | 2.582 | DISEASES 56903 | PAPOLB | 3.482 | DISEASES 5293 | PIK3CD | 2.901 | DISEASES 8544 | PIR | 4.498 | DISEASES 11128 | POLR3A | 2.112 | DISEASES 51334 | PRR16 | 2.359 | DISEASES 5646 | PRSS3 | 1.547 | DISEASES 57142 | RTN4 | 4.327 | DISEASES 100129060 | SEMA3F-AS1 | 3.236 | DISEASES 6462 | SHBG | 1.137 | DISEASES 10166 | SLC25A15 | 2.18 | DISEASES 6609 | SMPD1 | 2.149 | DISEASES 6949 | TCOF1 | 1.85 | DISEASES 360200 | TMPRSS9 | 4.59 | DISEASES 8936 | WASF1 | 4.049 | DISEASES 10163 | WASF2 | 3.437 | DISEASES |
| Locus | (Waiting for update.) |
| Disease ID | 333 |
|---|---|
| Disease | antisocial personality disorder |
| Integrated Phenotype | (Waiting for update.) |
| Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:12) HP:0000718 | Aggressive behaviour | 8 HP:0100710 | Impulsivity | 5 HP:0012075 | Personality disorder | 5 HP:0000739 | Anxiety | 5 HP:0012076 | Borderline personality disorder | 2 HP:0000757 | Lack of insight | 2 HP:0000734 | Disinhibition | 1 HP:0002592 | Stomach ulcer | 1 HP:0008760 | Violent behavior | 1 HP:0002353 | Abnormal EEG | 1 HP:0011999 | Paranoia | 1 HP:0100753 | Schizophrenia | 1 |
| Disease ID | 333 |
|---|---|
| Disease | antisocial personality disorder |
| Manually Symptom | UMLS | Name(Total Manually Symptoms:4) |
| Text Mined Symptom | UMLS | Name | Sentences' Count(Total Symptoms:3) |
Manually Genotype(Total Text Mining Genotypes:0) |
|---|
| (Waiting for update.) |
Text Mining Genotype(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
All Snps(Total Genotypes:1) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| snpId | pubmedId | geneId | geneSymbol | diseaseId | sourceId | sentence | score | Year | geneSymbol_dbSNP | CHROMOSOME | POS | REF | ALT |
| rs13134663 | 22297151 | 146 | ADRA1D | umls:C0003431 | BeFree | One SNP, rs13134663, in the collagen XXV alpha 1 gene (COL25A1) was significantly associated with ASPD in both African Americans and European Americans (smallest p values were .0002 and .0004, respectively). | 0.000271442 | 2012 | COL25A1 | 4 | 108919403 | A | G |
GWASdb Annotation(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
Mapped by lexical matching(Total Items:0) |
|---|
| (Waiting for update.) |
Mapped by homologous gene(Total Items:0) |
|---|
| (Waiting for update.) |
| Disease ID | 333 |
|---|---|
| Disease | antisocial personality disorder |
| Case | (Waiting for update.) |