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	acne rosacea

Disease ID	786
Disease	acne rosacea
Definition	an acne like skin disease occurring mostly in middle aged adults
Synonym	acne erythematosa acne rosacea (disorder) acne roscea acne, erythematosa acne, rosacea disorders rosacea rosacea rosacea (disorder) rosacea [disease/finding] rosacea acne rosacea nos rosacea nos (disorder)
DOID	DOID:8881
UMLS	C0035854
MeSH	D012393
SNOMED-CT	SNOMEDCT_US_2016_09_01:398909004
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:22) C0024236 \| lymphedema \| 2 C0011847 \| diabetes \| 2 C0011603 \| dermatitis \| 2 C0010043 \| corneal ulcer \| 1 C0015464 \| facial nerve palsy \| 1 C0033860 \| psoriasis \| 1 C0003467 \| anxiety \| 1 C0010346 \| crohn's disease \| 1 C0037274 \| skin disorder \| 1 C0376175 \| bell's palsy \| 1 C0042373 \| vascular disease \| 1 C0036508 \| seborrheic dermatitis \| 1 C0042870 \| vitamin d defic \| 1 C0022568 \| keratitis \| 1 C0004134 \| ataxia \| 1 C0022602 \| actinic keratoses \| 1 C0039446 \| telangiectasia \| 1 C0010068 \| coronary artery disease \| 1 C0042870 \| vitamin d deficiency \| 1 C0037274 \| skin disorders \| 1 C0007222 \| cardiovascular disease \| 1 C0011615 \| atopic dermatitis \| 1
Curated Gene	(Waiting for update.)
Inferring Gene	Entrez_id \| Symbol \| Resource(Total Genes:3) 2944 \| GSTM1 \| CIPHER 2950 \| GSTP1 \| CIPHER 2952 \| GSTT1 \| CIPHER
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:50) 488 \| ATP2A2 \| 1.041 \| DISEASES 545 \| ATR \| 1.942 \| DISEASES 2683 \| B4GALT1 \| 1.829 \| DISEASES 56244 \| BTNL2 \| 1.651 \| DISEASES 153571 \| C5orf38 \| 1.866 \| DISEASES 820 \| CAMP \| 5.005 \| DISEASES 6364 \| CCL20 \| 1.583 \| DISEASES 64764 \| CREB3L2 \| 1.253 \| DISEASES 2919 \| CXCL1 \| 1.257 \| DISEASES 54878 \| DPP8 \| 1.834 \| DISEASES 1832 \| DSP \| 1.025 \| DISEASES 2312 \| FLG \| 1.565 \| DISEASES 2316 \| FLNA \| 1.469 \| DISEASES 3039 \| HBA1 \| 1.153 \| DISEASES 23493 \| HEY2 \| 1.638 \| DISEASES 3122 \| HLA-DRA \| 1.692 \| DISEASES 3329 \| HSPD1 \| 1.42 \| DISEASES 3440 \| IFNA2 \| 1.144 \| DISEASES 3662 \| IRF4 \| 1.795 \| DISEASES 9622 \| KLK4 \| 1.961 \| DISEASES 25818 \| KLK5 \| 5.312 \| DISEASES 5650 \| KLK7 \| 2.454 \| DISEASES 4318 \| MMP9 \| 2.457 \| DISEASES 10198 \| MPHOSPH9 \| 2.881 \| DISEASES 727897 \| MUC5B \| 1.48 \| DISEASES 23077 \| MYCBP2 \| 2.766 \| DISEASES 114548 \| NLRP3 \| 1.174 \| DISEASES 594857 \| NPS \| 3.401 \| DISEASES 131870 \| NUDT16 \| 2.437 \| DISEASES 4948 \| OCA2 \| 2.208 \| DISEASES 341416 \| OR6C2 \| 2.07 \| DISEASES 5915 \| RARB \| 1.013 \| DISEASES 6278 \| S100A7 \| 1.29 \| DISEASES 123041 \| SLC24A4 \| 3.487 \| DISEASES 6590 \| SLPI \| 1.174 \| DISEASES 10285 \| SMNDC1 \| 2.611 \| DISEASES 10927 \| SPIN1 \| 2.767 \| DISEASES 11005 \| SPINK5 \| 2.325 \| DISEASES 56241 \| SUSD2 \| 2.23 \| DISEASES 6863 \| TAC1 \| 2.265 \| DISEASES 6949 \| TCOF1 \| 2.567 \| DISEASES 26136 \| TES \| 1.35 \| DISEASES 7124 \| TNF \| 1.565 \| DISEASES 7442 \| TRPV1 \| 2.07 \| DISEASES 51393 \| TRPV2 \| 1.709 \| DISEASES 162514 \| TRPV3 \| 2.141 \| DISEASES 7421 \| VDR \| 1.767 \| DISEASES 7422 \| VEGFA \| 1.666 \| DISEASES 7432 \| VIP \| 1.228 \| DISEASES 7433 \| VIPR1 \| 1.577 \| DISEASES
Locus	(Waiting for update.)

Disease ID	786
Disease	acne rosacea
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:23) HP:0010783 \| Erythema \| 11 HP:0001041 \| Blushing \| 6 HP:0001004 \| Lymphatic obstruction \| 2 HP:0010628 \| Facial palsy, unilateral or bilateral \| 2 HP:0003765 \| Psoriasis \| 1 HP:0001061 \| Acne \| 1 HP:0002958 \| Immune dysregulation \| 1 HP:0100280 \| Morbus Crohn \| 1 HP:0000559 \| Corneal scarring \| 1 HP:0002597 \| Abnormality of blood vessels \| 1 HP:0001677 \| Coronary artery disease \| 1 HP:0100512 \| Vitamin D deficiency \| 1 HP:0100699 \| Scarring \| 1 HP:0001047 \| Atopic dermatitis \| 1 HP:0001009 \| Telangiectases \| 1 HP:0200039 \| Pustules \| 1 HP:0012804 \| Corneal ulceration \| 1 HP:0000969 \| Dropsy \| 1 HP:0000491 \| Corneal inflammation \| 1 HP:0200034 \| Papule \| 1 HP:0001251 \| Ataxia \| 1 HP:0001051 \| Seborrheic dermatitis \| 1 HP:0000739 \| Anxiety \| 1

Disease ID	786
Disease	acne rosacea
Manually Symptom	UMLS \| Name(Total Manually Symptoms:6) C1611280 \| allergy C0850666 \| helicobacter pylori infection C0549398 \| meibomitis C0406486 \| ocular rosacea C0341024 \| familial chronic mucocutaneous candidiasis C0005741 \| blepharitis
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:5) C0041834 \| erythema \| 8 C0016382 \| flushing \| 5 C0009450 \| infection \| 2 C1402315 \| vascular lesions \| 1 C0039446 \| telangiectasia \| 1

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

Text Mining Genotype(Total Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:2)
snpId	pubmedId	geneId	geneSymbol	diseaseId	sourceId	sentence	score	Year	geneSymbol_dbSNP	CHROMOSOME	POS	REF	ALT
rs763035	25695682	56244	BTNL2	umls:C0035854	BeFree	Exploratory immunohistochemical analysis of HLA-DRA and BTNL2 expression in papulopustular rosacea lesions from six individuals, including one with the rs763035 variant, revealed staining in the perifollicular inflammatory infiltrate of rosacea for both proteins.	0.000271442	2015	NA	6	32427068	G	A
rs763035	25695682	3122	HLA-DRA	umls:C0035854	BeFree	Exploratory immunohistochemical analysis of HLA-DRA and BTNL2 expression in papulopustular rosacea lesions from six individuals, including one with the rs763035 variant, revealed staining in the perifollicular inflammatory infiltrate of rosacea for both proteins.	0.000271442	2015	NA	6	32427068	G	A

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:0)
(Waiting for update.)

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Disease ID	786
Disease	acne rosacea
Case	(Waiting for update.)

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