1. Introduction

X-CNV model requires two R packages, data.table and xgboost, and Bedtools v2.26.0. If the R packages and bedtools can not be installed automatically, users can install them by yourself. The executable file of bedtools should be placed in ./tools/.

2. Installation

sh Install.sh

3. Predicting CNV pathogenicity using X-CNV model

Usage:./bin/XCNV CNV.bed

4. Download

Github for XCNV:https://github.com/kbvstmd/XCNV.

The software package can be downloaded via the link XCNV_local_beta.tar.gz.

The software package V1.0.1 can be downloaded via the link XCNV_local_V1.0.1.tar.gz.

The pathogenicity scores for 557,892 unified CNVs by X-CNV. merged.cnv.data.output.csv.