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PedAM

Pediatric Disease Annotations & Medicines




Disease schizophrenia
Phenotype C0033975|psychosis
Sentences 84
PubMedID- 26199781 Several recent studies have shown that patients with a history of psychosis associated with bipolar disorder, schizophrenia, or schizoaffective disorder tend to display persistent eeg abnormalities even when not actively psychotic [5, 6].
PubMedID- 25367503 Several lines of evidence suggest that the effect of clozapine on muscarinic receptors may be important for the treatment of psychosis in patients with schizophrenia (barak, 2009; raedler et al, 2007, mckinzie and bymaster, 2012).
PubMedID- 25214388 Both hscrp and il-6 levels were associated with insidious psychosis onset, duration of illness and chronic schizophrenia course with deterioration.
PubMedID- 25385789 However, relationships between infections and acute psychosis in patients with schizophrenia have not been extensively explored.
PubMedID- 23450042 Dysfunction of nmda neurotransmission also plays a critical role in the pathophysiology of schizophrenia, which presents with mood disturbance, psychosis and cognitive decline similar to dementia [27].
PubMedID- 23755035 This suggests that disorders with an adolescent onset, as is the case with psychosis in schizophrenia, might be related to such subtle differences.
PubMedID- 22928856 Given the documented close relationship to other schizophrenic disorders, spd will be included in the psychosis section of dsm-5 as a schizophrenia spectrum disorder as well as in the personality disorder section.
PubMedID- 26467751 Our recent work shows that such features, measured in the anterior corpus callosum in diffusion mri data, correlate with psychosis symptoms in patients with adolescent onset schizophrenia and subside a reversal of normal sexual dimorphism.
PubMedID- 23632455 Hall et al.26 and keri et al.27 reported that the t/t genotype of the snp8nrg243177 (rs6994992) located in the nrg1 hapice schizophrenia-risk haplotype28 was associated with a 100% psychosis transition rate in two independent high-risk populations, the first a genetic high-risk (for example, family history of schizophrenia) sample and the second a clinical high-risk sample.
PubMedID- 23199972 Sga comparison; patients in their first episode of psychosis and diagnosed with schizophrenia-spectrum disorders; available data for psychopathology change, treatment response, treatment discontinuation, adverse effects, or cognition.
PubMedID- 23355782 The search used free text and mesh terms to identify studies in the following diseases: schizophrenia and disorders with psychotic features, psychosis, epilepsy, bipolar disorder, and major depressive disorder (depression).
PubMedID- 24704218 The relation between childhood maltreatment and psychosis in patients with schizophrenia and non-psychiatric controls.
PubMedID- 21772062 This study investigated neural changes following 6–8 months of cbt for psychosis in patients with schizophrenia using functional mri and an implicit affective processing task.
PubMedID- 24301645 Over the past 50 years, there have been many clinical and pharmacological studies implicating aberrant da signalling in the pathology of psychosis associated with schizophrenia and related disorders.5, 39, 40, 41, 42 animal models with deficits in each component of the dopaminergic pathway, such as da biosynthesis, da receptors and dat have provided valuable insight to the role of aberrant da signalling in the presentation of psychosis-like behavioural defects.43 however, many of these models have also shown paradoxical effects when compared with the human condition.
PubMedID- 23020880 Clozapine is unique among the atypical apds in its efficacy for ameliorating psychosis in patients with treatment-resistant schizophrenia (trs), for reduction of suicide, and for improving longevity.
PubMedID- 21845144 psychosis is particularly associated with schizophrenia, bipolar disorder, and severe depression.
PubMedID- 25085384 Method: this study analyzed cortical morphology using surface-based morphometry in 92 subjects (age range 11-18 years, 52 healthy controls and 40 adolescents with early-onset first-episode psychosis diagnosed with schizophrenia (n=20) or bipolar disorder with psychotic symptoms (n=20) based on a two year clinical follow up).
PubMedID- 25497442 Brain structure in people at ultra-high risk of psychosis, patients with first-episode schizophrenia, and healthy controls: a vbm study.
PubMedID- 23497716 Furthermore, approximately half of all epileptic patients with psychosis are diagnosed with schizophrenia [71].
PubMedID- 25705203 Although the relationship between avp and social behavior disorders has been difficult to establish in males, plasma levels of avp have been linked to severity of psychosis in women with schizophrenia (139).
PubMedID- 24023251 However, to our knowledge, no single study has addressed the possible differences in (1)h mrs abnormalities in subjects at 3 different stages of disease, including those at ultrahigh risk for psychosis (uhr), with first-episode schizophrenia (fes), and with chronic schizophrenia (chsz).
PubMedID- 21392377 Patients aged 18-37 years with first episode psychosis in schizophrenia spectrum, who in the inclusion period of the trials are treated for at least 11/2 year by one of the six opus teams will be asked to give signed informed consent to participate in the trial.
PubMedID- 23343417 Method: we conducted a cross-sectional comparison of cognitive insight (as indexed by the beck cognitive insight scale) in 62 help-seeking individuals at clinical high risk for psychosis, fifty-nine individuals with schizophrenia-spectrum disorders and 37 healthy controls (hc).
PubMedID- 25864951 Objective: this study aims to quantify facial emotion recognition abnormalities and their relation to neurocognitive dysfunction and schizotypy in individuals at ultra-high risk (uhr) for psychosis and patients with first-episode schizophrenia (fes).
PubMedID- 20624328 The criterion and construct validity of the non-clinical psychosis phenotype with schizophrenia demonstrates that it is a valid population in which to study the aetiology of psychosis.
PubMedID- 21200078 Cognitive-behavioural therapy for persistent and recurrent psychosis in people with schizophrenia-spectrum disorder: cost-effectiveness analysis.
PubMedID- 23006239 Phenomenology of first-episode psychosis in schizophrenia, bipolar disorder, and unipolar depression: a comparative analysis.
PubMedID- 25000154 A total of 666 patients with psychosis (predominantly schizophrenia), 673 siblings, 575 parents, and 585 controls were included in this study.
PubMedID- 26297373 Psychotic illness included schizophrenia, schizoaffective, bipolar with psychosis, depression with psychosis, delusional disorder, postanoxic or interferon-related psychosis, substance-induced psychosis and psychosis not otherwise specified.
PubMedID- 24765068 Together, this study suggests that a subset of genes involved in shaping the healthy maternal brain may also be dysregulated in mental health disorders and put females at risk for post-partum psychosis with aspects of schizophrenia and bpd.
PubMedID- 24917437 Alteration of serum bilirubin level in acute episodes of psychosis in patients with schizophrenia has been reported but the pattern of this alteration is controversial.
PubMedID- 24498053 Interestingly, recent studies found that grm3 polymorphisms (rs1989796 and rs1476455) were associated with symptoms of refractory global psychosis in patients with schizophrenia [9].
PubMedID- 21731632 The density of vens was determined using cresyl violet-stained sections of the acc of 39 individuals with psychosis (20 cases with schizophrenia, 19 with bipolar disorder).
PubMedID- 21278539 This study's aim was to investigate coping strategies and their relationship to symptoms in people at ultra high risk (uhr) for psychosis compared with recent-onset schizophrenia (spr) and healthy controls.
PubMedID- 26089815 Previous work found that injections of oxt reduce the symptoms of psychosis and anhedonia in patients with schizophrenia (62, 63).
PubMedID- 24113122 Controversial results concerning insulin resistance and lipid metabolism have been reported in antipsychotic-naive first-episode psychosis (an-fep) patients with schizophrenia of different countries.
PubMedID- 24012461 Background: a shorter duration of untreated psychosis in patients with schizophrenia results in better symptomatic and functional outcomes.
PubMedID- 25403891 Overall, one-fifth (19.8%) experienced a recent psychotic episode, while a further 14.5% were categorised as having an existing psychosis (46.7% with a schizophrenia diagnosis), amongst whom there were relatively high rates of comorbid substance misuse (52.9%), psychosocial (70.2%) and physical health (37.7%) problems.
PubMedID- 21040459 Znf804a, encoding the transcription factor zinc-finger protein 804a, is a genome-wide supported psychosis gene associated with schizophrenia and bipolar disorder.
PubMedID- 20718964 In spite of these overlaps, there has been little research examining the characteristics and symptoms of psychosis within both schizophrenia and bipolar disorder, which could yield evidence of commonalities as well as differences among patients with psychosis [25].
PubMedID- 25539511 The stereotypical psychosis associated with schizophrenia represents the positive symptoms of the disease, consisting of hallucinations and paranoid delusions.
PubMedID- 24314907 Disrupted action monitoring in recent-onset psychosis patients with schizophrenia and bipolar disorder.
PubMedID- 26025014 Structural magnetic resonance imaging of the brain was performed in 44 first-episode psychosis patients (with diagnoses of schizophrenia or schizophreniform disorder) and 25 healthy controls.
PubMedID- 23805069 Antipsychotic drugs are used to treat psychosis in schizophrenia but they have also been connected with normalization of some immune parameters in some animal models of schizophrenia.
PubMedID- 20361061 In addition to its use in dementia, aripiprazole may be effective for the treatment of a variety of psychiatric conditions in the elderly including psychosis due to schizophrenia, bipolar disoder, depression, and pd.
PubMedID- 22129906 Indeed, paradoxical gabapentin-induced exacerbation of psychosis in a patient with schizophrenia has already been described [17].
PubMedID- 20573264 In contrast, tropisetron and dmxb-a have not been reported to induce psychosis in patients with schizophrenia (this study, and [14]).
PubMedID- 23769679 Conclusions: loss of body weight is a serious health problem in schizophrenia patients with severe psychosis syndrome, especially the negative syndrome.
PubMedID- 25987916 Marijuana correlates with the onset of psychosis in patients with schizophrenia and perhaps bipolar disorder as well.29–32 about half of patients with cannabis psychosis will later be diagnosed with a primary psychotic disorder.8,33 this high rate may reflect high rates of marijuana use among patients with schizophrenia.
PubMedID- 25048005 It is evident that once psychosis is present in patients with schizophrenia, the underlying biological process of the illness has already been ongoing for many years.

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