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PedAM

Pediatric Disease Annotations & Medicines




Disease schizophrenia
Phenotype |psychosis
Sentences 84
PubMedID- 23218100 Objective: to compare longer-term safety and effectiveness of the 4 most commonly used atypical antipsychotics (aripiprazole, olanzapine, quetiapine, and risperidone) in 332 patients, aged > 40 years, having psychosis associated with schizophrenia, mood disorders, posttraumatic stress disorder, or dementia, diagnosed using dsm-iv-tr criteria.
PubMedID- 25716487 The authors studied ppi deficits in first episode psychosis (fep) with schizophrenia and cannabis abuse influence.
PubMedID- 23840971 A hyperdopaminergic state in subcortical regions is believed to be associated with psychosis, a core constituent of positive symptoms of schizophrenia and a phenotype often observed in manic phase of the bipolar disorder, and a symptom that can be ameliorated using treatment with d2 blockers.
PubMedID- 26553191 Taken together, the literature suggests that people at chr of psychosis and people with schizophrenia may have a particular sensitivity to brain tissue loss after exposure to cannabis.
PubMedID- 22283754 Although current antipsychotic drugs treat psychosis in schizophrenia rather well, their impact on cognitive dysfunction is minimal.
PubMedID- 24956976 Method: a total of 299 first-episode psychosis (fep) patients with schizophrenia spectrum disorders were assessed for depressive symptoms with panss depression item (g6) at baseline, and 1, 2, 5 and 10 years of follow up.
PubMedID- 25841662 We recruited 17 subjects at ultra-high-risk (uhr) for psychosis, 10 non-affected siblings of patients with schizophrenia (familial high risk [fhr]) and 15 healthy controls.
PubMedID- 23430971 Response was defined as a rating of mild or better on all of the positive symptom items of the schedule for affective disorders and schizophrenia change version with psychosis and disorganization items.
PubMedID- 20393098 Of those women with psychosis, 62.7% were diagnosed with schizophrenia, 19.6% with bipolar disorder, 17.6% with schizoaffective disorder, and 29.4% with other psychotic disorders.
PubMedID- 25726022 The aim of the study was to analyze changes in functional adjustment from childhood to 2 years after the first episode of psychosis (fep) in patients with early-onset schizophrenia spectrum disorders (ssd) and affective psychoses (afp) and a good or intermediate level of premorbid adjustment.
PubMedID- 22347194 Our case study is a first-episode psychosis leading to a schizophrenia and it was compared to a group a young schizophrenia patients.
PubMedID- 18682375 A wide range of cognitive deficits are present at the onset of psychosis in people with schizophrenia.1,2 large-scale studies comparing schizophrenia patients, recruited in an unbiased way as they present with their first psychotic episode, with healthy controls, recruited from the same community, find decrements in memory and executive function as well as wechsler adult intelligence scale (wais) iq.3–6 when general intellectual ability is controlled by matching for wais iq, impairments in memory and executive function can still be discerned in patients with first-episode and more long-term schizophrenia.7–11 such findings suggest that impairments in these cognitive domains are central to schizophrenia.
PubMedID- 21483430 Furthermore, individuals at ultra high risk for psychosis and relatives of individuals affected with schizophrenia also show reduction in cortical thickness in certain brain regions (50, 65-67), suggesting a strong genetic component to regional cortical thinning, which may be progressive in nature.
PubMedID- 23372240 This data very clearly reveals that the major load of clinical work in a private psychiatric set-up constitutes of affective disorders and other minor psychiatric disorders while schizophrenia with acute psychosis constitutes 20% of the work load only.
PubMedID- 25052782 It also may reflect a familial risk for psychosis in schizophrenia-spectrum disorders and bipolar disorder.
PubMedID- 24490070 [17] found increased qt variability but shorter qt mean intervals in 25 unmedicated schizophrenia patients with acute psychosis compared to healthy controls.
PubMedID- 24682777 (2012) found that higher hcy levels may predict a shorter duration of untreated psychosis (dup) in patients with first-episode schizophrenia-spectrum disorders.
PubMedID- 23047785 We used va pharmacy benefits management data to examine antipsychotic use and va medical sas datasets and the minimum data set to identify evidence-based indications for antipsychotic use (eg, schizophrenia, dementia with psychosis).
PubMedID- 22138503 psychosis in schizophrenia is associated with source-monitoring deficits whereby self-initiated behaviors become attributed to outside sources.
PubMedID- 26030357 Moreover, subjects at uhr for psychosis and patients with schizophrenia are generally less educated than healthy controls.
PubMedID- 25819937 Childhood onset schizophrenia (cos), with onset of psychosis before age 13, is a rare form of schizophrenia that represents a more severe and chronic form of the adult onset illness.
PubMedID- 21700346 Substantial evidence suggests that psychosis in schizophrenia is associated with dysregulation of subcortical dopamine system function.
PubMedID- 24575073 Besides, acute psychosis in schizophrenia manifests itself with a collapse of the temporal dimension of the narrative plot, which leads to a de-contextualization of self-experience (holma and aaltonen, 1997, 2004a; france and uhlin, 2006).
PubMedID- 26462502 Objective: the complex molecular etiology of psychosis in schizophrenia (sz) and psychotic bipolar disorder (pbp) is not well defined, presumably due to their multifactorial genetic architecture.
PubMedID- 23355817 The fully dimensional approach by claridge suggests an intra-individually stable array of traits, whereby high schizotypy-values increase the risk of developing psychosis and persons with schizophrenia-spectrum disorders show particularly high scores in schizotypy with no clear cut-off or distribution break indicating membership of a risk group.
PubMedID- 20154201 For example, a recent article documented performance on the intradimensional/extradimensional (ided) test from the cambridge neuropsychological test automated battery on 262 patients from the west london first-episode psychosis study (232 with schizophrenia) and 76 control subjects.32 although many studies using this test focus on aspects of attentional set shifting that characterize its latter stages, in fact the task involves participants learning from feedback while passing through various stages of learning.
PubMedID- 21652178 161 patients with psychosis (96 patients diagnosed with schizophrenia and 65 patients diagnosed with bipolar disorder) and 76 healthy control subjects were tested with both instruments to examine their concurrent validity relative to a more comprehensive neuropsychological assessment battery.
PubMedID- 22355185 Introduction: the extended psychosis phenotype--relationship with schizophrenia and with ultrahigh risk status for psychosis.
PubMedID- 23661632 The overall concordance between 4 categorical diagnostic groups (schizophrenia, mania with psychosis, psychotic depression and schizoaffective disorder) and dimensional symptom ranged from 62.2% to 73.1% (when the schizoaffective group was excluded).
PubMedID- 24971292 Among adult perpetrators, schizophrenia with symptoms of psychosis present at the moment of the parricide, was the most common diagnosis (7).
PubMedID- 21939612 Treatment response, the primary outcome measure, was defined as a rating of mild or better on all of the positive symptom items on the schedule for affective disorders and schizophrenia change version with psychosis and disorganization items.
PubMedID- 24262680 The aim of this study is to compare the neurocognitive functions in individuals with clinical or genetic risk for psychosis, in patients with first-episode schizophrenia (fes) and in healthy controls.
PubMedID- 26097750 (2009) reported that comorbid lifetime cannabis, but not alcohol, abuse/dependence was associated with a statistically significant 3-year-earlier age at onset of psychosis in schizophrenia (n = 80), schizoaffective disorder (n = 61), and bipolar disorder with psychotic features (n = 92).
PubMedID- 25880803 Psychiatric-related hospitalization is often the consequence of a relapse or exacerbation of psychosis for patients with schizophrenia [28].

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