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PedAM

Pediatric Disease Annotations & Medicines




Disease proteinuria
Phenotype C0020538|hypertension
Sentences 94
PubMedID- 22447695 Pe is a multifactorial disease characterized by hypertension with proteinuria, which is a leading cause of maternal and neonatal morbidity and mortality occurring in 5-7% of pregnancies worldwide.
PubMedID- 21215946 Recent studies have also begun to explore the relationship that systemic hypertension may have with proteinuria and the progression of kidney disease.
PubMedID- 24223202 Preeclampsia is a pregnancy specific syndrome, clinically characterized by the presence of hypertension, associated with proteinuria in the second half of pregnancy [1].
PubMedID- 26258813 Increased risk from pregnancy induced hypertension without proteinuria and with proteinuria (pre-eclampsia) relates mainly to the association with kidney disease in diabetes, and poor glycemic control.
PubMedID- 24600275 hypertension in children with overt proteinuria or progressive renal insufficiency is also an indication for lowering blood pressure to below the 90th percentile.
PubMedID- 26451724 The diagnosis of pe was based on the onset of hypertension (≥140/90mmhg) with proteinuria (≥0.3g/24h, or ≥1+ by dipstick) after 20 weeks of gestation in a woman with previously normal blood pressure, and could be accompanied by symptoms such as upper abdominal discomfort, headache, and blurred vision, according to previously published criteria [18].
PubMedID- 26426627 In summary, by improving proteinuria or albuminuria in patients with primary hypertension, especially those with dm, the widespread use of aceis may improve many clinical outcomes.
PubMedID- 26238999 The aim of this study was to evaluate the agreement between self-reported perinatal outcomes (gestational hypertension with or without proteinuria, gestational diabetes, premature birth and low birth weight) in a longitudinal study and linked to administrative data (medical records).
PubMedID- 25775254 4a-b), indicating marked hypertension associated with proteinuria and renal glomerular damage after 6 weeks of hs diet.
PubMedID- 22107134 Preeclampsia (pe), which is defined as new onset hypertension after 20 weeks of pregnancy accompanied by proteinuria, is characterized by inadequate placentation, oxidative stress, inflammation and widespread endothelial dysfunction.
PubMedID- 24130760 It is possible that some women in pe300 may have developed gestational proteinuria with pre-existing hypertension, rather than a true ‘pre-eclampsia’ syndrome, and therefore had more benign outcomes than the women in pe500.
PubMedID- 23514843 To further investigate the interaction of proteinuria with hypertension and diabetes, logistic regression was separately performed in urban and rural residents (table 4).
PubMedID- 23246316 Further, among women we found maternal hypertension without proteinuria that was associated with more frequent complaints of cognitive failures, forgetfulness, and false triggering.
PubMedID- 20345850 These include the recent avoid trial [26] in which aliskiren reduced proteinuria in patients with hypertension, type 2 diabetes and diabetic nephropathy.
PubMedID- 22140321 Pre-eclampsia is defined as new onset hypertension with proteinuria during pregnancy.
PubMedID- 22934182 These rats developed glomerular endotheliosis and exhibited hypertension with proteinuria by day 17 (early third trimester) [68].
PubMedID- 26044306 Pe was diagnosed if gestational hypertension was associated with proteinuria > 300 mg/24h, after 20 weeks of gestation.
PubMedID- 22523250 Preeclampsia is defined as new-onset hypertension with proteinuria after 20 wk gestation and is hypothesized to be due to shallow trophoblast invasion in the spiral arteries thus resulting in progressive placental ischemia as the fetus grows.
PubMedID- 23826935 I: eclampsia is defined as the presence of hypertension associated with proteinuria and fits.
PubMedID- 24703162 Objective: to study whether pre-eclampsia and hypertension without proteinuria during pregnancy are associated with adaptive functioning, and psychiatric and psychological problems, of older offspring.
PubMedID- 21694938 Even without dust exposure, very prolonged space flight may lead to renovascular hypertension with evidence of self-limiting proteinuria, impairment in renal concentrating ability, and elevations of serum creatinine.1 in addition, with space flight, there is reduced diurnal blood pressure variation which portends kidney disease.
PubMedID- 23613821 Eclampsia is defined as the presence of hypertension associated with proteinuria and fits.
PubMedID- 25202276 Discussion continues as to whether de novo hypertension in pregnancy with significant proteinuria (pre-eclampsia; pe) and non-proteinuric new hypertension (gestational hypertension; gh) are parts of the same disease spectrum or represent different conditions.
PubMedID- 21636798 As previously described (19), pre-eclampsia was defined as gestational hypertension with proteinuria for previously normotensive women, according to the international society for the study of hypertension in pregnancy guidelines (4) and according to national high blood pressure education program working group's guidelines for women with pre-existing hypertension and/or proteinuria (5).
PubMedID- 24742720 Among included women, 364 developed gestational hypertension (hypertension without proteinuria) and 131 developed preeclampsia (hypertension with proteinuria).
PubMedID- 24548847 Objective: preeclampsia is a multisystem disorder recognized as hypertension with proteinuria developing >20 weeks' gestation.
PubMedID- 24349782 Preeclampsia (pe) is hypertension with proteinuria that develops during pregnancy and affects at least 5% of pregnancies.
PubMedID- 24228792 Pih is a syndrome of hypertension with or without proteinuria, with the clinical manifestation usually occurring late in pregnancy and regressing after delivery.
PubMedID- 23920083 Preeclampsia was the primary outcome in dapit and was defined as gestational hypertension with proteinuria for previously normotensive women according to the international society for the study of hypertension in pregnancy (isshp) guidelines (1) and according to the national high blood pressure education program working groups guidelines for women with preexisting hypertension or proteinuria (2), as previously described (19).
PubMedID- 26259119 Medical doctors examined hospital records to verify the preeclampsia diagnosis of the 1161 identified preeclamptic pregnancies of 1003 women against the currently used national criteria, reproducible hypertension with proteinuria [9,10].
PubMedID- 25807547 In this study, we investigated the functional interactions between at1 receptor and ccr2 both in vitro, using hek293ft cells, and in vivo, using the sub-total nephrectomized (stnx) rat model characterized by extensive renal mass ablation associated with glomerular ras upregulation, glomerular hypertension, development of podocyte loss, progressive proteinuria and declining gfr associated with interstitial macrophage infiltration, glomerulosclerosis, and tubulointerstitial fibrosis [31–33].
PubMedID- 24308214 In essential hypertension the onset of de novo proteinuria is associated with faster rate of progression of disease.
PubMedID- 23937721 Thus, the sensitivity of the plgf test for fetal risk (iugr, abnormal fetal flow, pathological ctg, oligohydramnios, preterm delivery) in the hypertension group with and without proteinuria was excellent.
PubMedID- 21486720 Prevalence rates of hypertension (with or without proteinuria) among pregnant patients 13–45 years of age, recorded between july 2008 and march 2010 in uhc, dacope, bangladesh.
PubMedID- 22368905 All women developing hypertension with or without proteinuria after 20 weeks of pregnancy (n = 218) were included.
PubMedID- 23064954 Toxicities included the following: grade 4 neutropenia, febrile neutropenia, grade 4 anemia, platelet count below 25,000, serum creatinine at least 2 times baseline or upper limit of normal, grade 3 proteinuria with uncontrolled hypertension or renal impairment and grade 4 proteinuria, grade 3 or higher non-hematologic toxicity (except fatigue but including nausea, vomiting, and diarrhea not controlled by supportive treatment), grade 3 uncontrolled hypertension, grade 4 hypertension, delay of treatment for more than 3 weeks, or inability to receive 75 % of scheduled doses in a treatment cycle.
PubMedID- 26083525 A previous study indicated that the combination of acei and furosemide was a risk factor for cin because it significantly decreased gfr and increased proteinuria in patients with diabetes and hypertension [49].
PubMedID- 20580423 The primary outcome was pre-eclampsia, which we defined as gestational hypertension with proteinuria in accordance with the international society for the study of hypertension in pregnancy guidelines.1 gestational hypertension was defined as two diastolic blood pressure readings of 90 mm hg or more at least 4 h apart, or one reading of at least 110 mm hg, occurring after 20 weeks' gestation or up to 48 h postnatally and excluding labour.
PubMedID- 24778868 In both sle and preeclampsia, for example, women develop worsening proteinuria with hypertension and edema.
PubMedID- 22366876 Pediatric indications were uti (n = 9) or large proteinuria (n = 2), compared with hypertension, uti, lithiasis, renal carcinoma, and polycystic kidney disease in the adult patients [29].
PubMedID- 23812509 Women who have hypertension with proteinuria and/or edema that happens after 20th gestational week were defined as preeclamptic pregnant women.
PubMedID- 25628644 Nevertheless, preeclampsia (i.e., hypertension with proteinuria) is a major cause of both maternal and fetal mortality and morbidity (haig, 1993).
PubMedID- 25286010 The most common grade 3/4 toxicities were hypertension (46% of cases) and proteinuria (14%).
PubMedID- 21058447 The patient's condition was complicated by hypertension with increase in proteinuria at 22 weeks of gestation.
PubMedID- 22762533 Main outcome measures: preeclampsia, defined as gestational hypertension with proteinuria or any multi-system complication of preeclampsia.
PubMedID- 20798560 Nonhematologic toxicity in arm a involved hypertension in 23 (20.2%) of the patients and proteinuria in 7 (6.1%); 3 patients experienced hemorrhage and 1 patient intestinal perforation.
PubMedID- 25303561 It is characterized by the onset of new hypertension with proteinuria after 20 weeks of gestation.
PubMedID- 25472691 In the present study, the risk of pregnancy-induced hypertension with or without proteinuria was greater in the gestational diabetes and pre-existing diabetes groups than in the normal pregnancy group, and this risk was greater in the gestational diabetes group than in the pre-existing diabetes group regardless of adjusting.
PubMedID- 23991329 Refractory hypertension with massive proteinuria may be reversed in renal artery stenosis patients with low proteinuria selectivity index after stenting.
PubMedID- 22169528 Conclusions: hypertension without proteinuria in pregnancy was associated with a higher risk of serious mental disorders in the offspring in adulthood.

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