PedAM
Pediatric Disease Annotations & Medicines
| Disease | epilepsy |
| Phenotype | C0011570|depression |
| Sentences | 65 |
| PubMedID- 23594674 | Conversely, a pre-existing diagnosis of depression among patients with new-onset epilepsy is up to seven times more common than in a control population[14]. |
| PubMedID- 22681163 | The prevalence of depression in patients with epilepsy (pwe) is high. |
| PubMedID- 23394027 | Comorbid depression in epilepsy affects negatively the health-related quality of life, increases suicide risk and costs of medical care when compared to patients without depression selective serotonin reuptake inhibitors and selective serotonin and norepinephrine reuptake inhibitor are first-line treatment of depression in patients with epilepsy. |
| PubMedID- 22099527 | depression in patients with temporal lobe epilepsy (tle) is highly prevalent and carries significant morbidity and mortality. |
| PubMedID- 24074883 | Conclusion: symptoms of depression were associated with epilepsy both during and before pregnancy. |
| PubMedID- 23549791 | In our review, the association of depression with duration of epilepsy was found to be inconsistent. |
| PubMedID- 22162974 | We then show that depression in epilepsy provides a perfect model for the biopsychosocial etiology of depression and discuss related therapeutic approaches. |
| PubMedID- 26284748 | There is a high prevalence of depression in patients with epilepsy, which negatively impacts their quality of life (qol) and seizure control. |
| PubMedID- 25667841 | Eighth, in the context of multiple potential risk factors for the development of de novo major depression with suicide attempt (epilepsy, treatment with aed, lev titration, past alcohol dependence, traumatic brain injury with intracranial hemorrhage, basal ganglia and thalamic lacunar infarcts, and potential genetic predisposition), the probability of lev titration inducing the de novo major depression with associated near fatal suicide attempt was determined by the naranjo's adverse reaction probability scale as probable (scored as 5) [30]. |
| PubMedID- 20858043 | Results indicate hypoactivity in the frontal cortex and hippocampus, and hyperactivity in the left dorsomedial prefrontal cortex for depression (with and without epilepsy). |
| PubMedID- 21742562 | The results suggest that screening for depression in patients with epilepsy via gps improves detection of depression and is acceptable to interviewed patients. |
| PubMedID- 24032437 | Cognitive behavioral therapy (cbt) is a recommended treatment for depression in people with epilepsy (pwe); however, a recent cochrane review found that there was insufficient evidence that any psychological therapy is effective. |
| PubMedID- 25478138 | This approves our second hypothesis that occurrence of depression in epilepsy bears an association with seizure frequency. |
| PubMedID- 26576071 | To the best of our knowledge, our study is the first study that has attempted to compare the frequencies of both depression and anxiety in patients with epilepsy to another chronic brain disorders, in this case, ms. previous studies have compared the rates of depression to other chronic medical conditions. |
| PubMedID- 25597526 | Primary study aims included the examination of 1) rates of self-reported depression in youth with epilepsy, 2) differences in depression by demographic and medical variables, 3) the impact of depression on hrqol, and 4) changes in depression and suicidal ideation following a behavioral medicine consultation. |
| PubMedID- 24138845 | The aim of the present study was therefore to firstly establish an animal model for depression associated with epilepsy, and secondly, to evaluate the potential of an aqueous macerate of the bulb of g. dalenii as a possible treatment modality for epilepsy-associated depression. |
| PubMedID- 25082253 | Aim: to compare the levels of anxiety and depression in patients with milder epilepsy characterized by complex partial seizures versus more severe epilepsy comprised of generalized tonic-clonic seizures. |
| PubMedID- 21093520 | The wag/rij strain: a genetic animal model of absence epilepsy with comorbidity of depression [corrected]. |
| PubMedID- 25597527 | Objective: depression in people with epilepsy (pwe) is underdiagnosed and undertreated. |
| PubMedID- 20851689 | Further education of community physicians and neurologists regarding the importance of treating depression in patients with epilepsy and research into the use of antidepressants in this population are indicated. |
| PubMedID- 23175727 | Objective: to estimate the prevalence of depression in persons with epilepsy (pwe) and the strength of association between these 2 conditions. |
| PubMedID- 23577079 | Another study has also shown that the relative risk of depression among individuals with epilepsy is higher in older individuals compared to those without epilepsy [52]. |
| PubMedID- 21725390 | Results: diagnosing depression in patients with epilepsy may be difficult, because the symptoms are somewhat atypical and appear episodically. |
| PubMedID- 22737444 | depression and anxiety in patients with epilepsy, with or without other chronic disorders. |
| PubMedID- 26076841 | Purpose: the comorbidity of depression in patients with epilepsy is common and treatment is still controversial. |
| PubMedID- 24971259 | Studies have found that depression causes disability in patients with epilepsy and reduces the patient's quality of life more than the epilepsy itself; and this is dangerous since it could lead to suicidal thoughts or suicide (9). |
| PubMedID- 26368332 | Clinical data demonstrate a 30–35% lifetime prevalence of depression in patients with epilepsy, and patients diagnosed with depression have a three to sevenfold higher risk of developing epilepsy. |
| PubMedID- 22957244 | Anhedonia has also been proposed as a better marker for depression in patients with epilepsy, in part secondary to its independence from physical symptoms associated with medications and chronic illness [32]. |
| PubMedID- 21219608 | Suicide attempts are not infrequent in depressed subjects and depression is commonly associated with epilepsy [42]. |
| PubMedID- 23673289 | depression in patients with newly diagnosed epilepsy predicts lamotrigine-induced rash: a short-term observational study. |
| PubMedID- 26033229 | The present study examined anxiety and depression in adolescents with epilepsy and the association of these disorders with seizure-related and sociodemographic variables. |
| PubMedID- 23533737 | Indicating the frequent cooccurrence of depression in patients with epilepsy, c. s. garcia describes recent efforts in diagnosis and management of depression in those with epilepsy. |
| PubMedID- 22766393 | Wag/rij rats represent a validated genetic animal model of absence epilepsy with mild-depression comorbidity, also including other behavioral alterations. |
| PubMedID- 23233847 | Adult epilepsy patients with depression, anxiety disorders, and sub-syndromic depression have significantly higher aed adverse effect profiles than those without these diagnoses (kanner et al., 2012). |
| PubMedID- 21701630 | The prevalence of depression in epilepsy patients ranges from 20%–55%28 and psychosis has been reported in 6%–9%.29 these rates are significantly higher than those seen in the general population. |
| PubMedID- 22018800 | Objective: the aim of the work described here was to measure the role of psychopathological features, specifically impulsivity and depression, in suicidality in patients with temporal lobe epilepsy (tle). |
| PubMedID- 22787593 | Some of the clinical features of depression in patients with epilepsy suggest a neurobiological connection, although it is difficult to eliminate psychosocial and iatrogenic factors in human studies. |
| PubMedID- 26482788 | A comparative study have also shown that the rate of depression in patients with epilepsy is significantly higher than the rate of depression in patients with other chronic diseases such as diabetes or asthma and the general population as well [13]. |
| PubMedID- 24341899 | Therefore, common pathogenic mechanisms may be involved in the etiology of depression comorbid with different epilepsy syndromes, and we would expect that this should be demonstrable in patients having different clinical characteristics of epilepsy, such as those included in the current study. |
| PubMedID- 24167947 | The purpose of this article is to review strategies used in the pharmacologic treatment of depression in patients with epilepsy, choice of antidepressants, effects of antidepressants on seizure threshold, pharmacokinetic interactions between antidepressant drugs and antiepileptic drugs and psychotropic properties of antiepileptic drugs. |
| PubMedID- 26556677 | Combined use of nddi-e and who-5 is recommended, since 95% of all epilepsy patients with depression and/or anxiety disorder are identified with only a modest number of false positives. |
| PubMedID- 26481533 | Background: the incidence rate of depression among patients with epilepsy is relatively high. |
| PubMedID- 25807125 | Objective: to assess depression and anxiety symptoms of adolescents with epilepsy compared with adolescents without epilepsy. |
| PubMedID- 24657500 | Determinants of depression among patients with epilepsy in athens, greece. |
| PubMedID- 20888306 | depression in epilepsy is associated with lack of seizure control. |
| PubMedID- PMC3943350 | The second speaker will focus on the biopsychosocial model of depression in epilepsy with special emphasis on the similarities between the two disorders with respect to genetic predisposition, neurotransmitters, and stress. |
| PubMedID- 20618406 | Taken into account that exercise can exert beneficial actions such as reduction of seizure susceptibility as observed in animal studies, and improvement of quality of life and reduction of anxiety and depression of individuals with epilepsy, physical exercise can be a potential candidate to be integrated with conventional therapy for epilepsy. |
| PubMedID- 24863509 | The relationship between sleep quality, depression, and anxiety in patients with epilepsy and suicidal ideation. |
| PubMedID- 24561543 | Controversy exists regarding the similarity between depression as seen in patients with epilepsy and in those with idiopathic major depression. |
| PubMedID- 24681386 | Screening for depression in people with epilepsy: comparative study among neurological disorders depression inventory for epilepsy (nddi-e), hospital anxiety and depression scale depression subscale (hads-d), and beck depression inventory (bdi). |
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