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PedAM

Pediatric Disease Annotations & Medicines




Disease epilepsy
Phenotype |depression
Sentences 65
PubMedID- 22050514 Purpose: memory deficits and depression are common in patients with temporal lobe epilepsy (tle).
PubMedID- 24912293 For example, interictal depression in individuals with epilepsy is more prevalent than in the general population or among patients with other chronic disorders.
PubMedID- 22934159 Psychosocial factors predisposing to depression in people with epilepsy include adjustment difficulties, limitations and restrictions in social settings which the disorder imposes, as well as the unpredictable nature of the seizures and the associated feelings of helplessness and loss of control over one's life.
PubMedID- 22871254 Subjects completed the state and trait anxiety inventory and the beck depression inventory; patients with epilepsy also completed the epilepsy foundation concerns index.
PubMedID- 25889039 We have previously reported neuropathological alterations in mesial temporal lobe epilepsy (mtle) patients with major depression and psychosis that suggest a morphological and neurochemical basis for psychopathological symptoms.
PubMedID- 21750525 depression in epilepsy can be described in the general framework of the diathesis-stress model: chronic stress exposure owing to the 'burden of epilepsy' and learned helplessness due to the threat of recurrent seizures as unpredictable aversive events represent psychological risk factors for the development of depression.
PubMedID- 26491329 Purpose: the aim of this study was to assess the prevalence of depression among patients with epilepsy and to establish the risk factors of depression in that group, with special focus on the use of potentially depressogenic medications.
PubMedID- 23326249 It is well known that epilepsy is comorbid with depression, as well as the fact that several antiepileptics can cause depression (e.g., hydantoins, succinimides, clonazepam, phenytoin) [16], [29].
PubMedID- 23049195 Indeed, some authors estimate the lifetime prevalence of depression in association with epilepsy to be as high as 55%.
PubMedID- 22632407 The clinical manifestations of depression in people with epilepsy (pwe) are pleomorphic, often associated with anxiety symptoms and anxiety disorders.
PubMedID- 23520221 Aims: to examine the efficacy of bright light therapy for symptoms of anxiety and depression in adults with focal epilepsy (trial registration at clinicaltrials.gov: nct01028456).
PubMedID- 23209983 This finding is similar to earlier findings from west africa which showed that age, gender, and living environment did not significantly influence depression among patients with epilepsy even though higher frequency of depression was found in females.
PubMedID- 22197509 Given that psychosocial factors are potentially modifiable, a better understanding of their role in the development of depression in people with epilepsy is urgently needed to guide effective treatments.
PubMedID- 20934354 Methods: outpatients filled out questionnaires, including the hospital anxiety and depression scale, the quality of life in epilepsy-10 questionnaire, the stigma scale, and a questionnaire on episodes of discrimination.
PubMedID- 22720001 Affective disorders (e.g., anxiety and depression) frequently co-occur with epilepsy, producing a negative impact on the quality of life of those affected [1], [2].

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