PedAM
Pediatric Disease Annotations & Medicines
| Disease | hypoglycemia |
| Phenotype | |diabetes |
| Sentences | 306 |
| PubMedID- 23150283 | In contrast, one patient had very mild hypoglycemia only with conversion to diabetes in puberty, without any clue of mosaicism, type 1 diabetes, type 2 diabetes, or additional diabetes gene mutations. |
| PubMedID- 24319123 | There were no significant differences in wm structure between children with type 1 diabetes who experienced episodes of severe hypoglycemia or seizures and those who did not. |
| PubMedID- 23425012 | Dapagliflozin added to metformin for 102 weeks enabled sustained reductions in hba1c, fpg, and weight without increased risk of hypoglycemia in patients with type 2 diabetes who were inadequately controlled on metformin alone. |
| PubMedID- 21722581 | Background: real-time continuous glucose monitoring (rt-cgm) improves hemoglobin a1c (a1c) and hypoglycemia in people with type 1 diabetes mellitus and those with type 2 diabetes mellitus (t2dm) on prandial insulin; however, it has not been tested in people with t2dm not taking prandial insulin. |
| PubMedID- 24853553 | This study assesses the impact of missed insulin doses and prevalence of mistimed and reduced insulin doses and mild hypoglycemia in patients with type 2 diabetes treated with basal insulin analogues in spain, and compares the data collected to pooled data from 8 other european countries (oecs). |
| PubMedID- 24810150 | Among those with diabetes-related hospitalizations, the incidence of hospitalization-related hypoglycemia in patients >/=65 years of age was greater than in patients <65 years of age (0.59 compared to 0.16 per 1000 person years). |
| PubMedID- 23683963 | Hospitalizations due to severe hypoglycemia in patients with diabetes mellitus in spain. |
| PubMedID- 22357185 | Likewise, long-term (52 weeks) treatment with the once-weekly formulation of exenatide (eqw) led to sustained improvements in glycemic control, in the presence of body weight reduction and low hypoglycemia event rates in patients with type 2 diabetes (3). |
| PubMedID- 24319119 | Objective: to develop and pilot a novel intervention addressing motivational and cognitive barriers to avoiding hypoglycemia in people with type 1 diabetes and persistent impaired awareness of hypoglycemia (iah) despite training in flexible insulin therapy. |
| PubMedID- 22934852 | This review examines the neurodegenerative events associated with diabetes, highlighting the role of hyperglycemia and/or hypoglycemia on cognitive function. |
| PubMedID- 24224883 | Several studies suggest that the use of insulin analogs instead of human insulin may lower the risk of severe hypoglycemia in women with diabetes [9–11]. |
| PubMedID- 23874102 | Fear and psychological discomfort were observed as important aggravating factors of hypoglycemia among patients with type 2 diabetes mellitus (table 3). |
| PubMedID- 23939392 | We previously reported that rats exposed to recurrent hypoglycemia and those with insulin deficient diabetes exhibit higher extracellular concentrations of gaba in the vmh and that this increase in tonic inhibition contributes to the counterregulatory defect (3,4). |
| PubMedID- 25834461 | Nevertheless, there is concern regarding the potential for hypoglycemia in patients with type 2 diabetes treated with dpp-4 inhibitors and sulfonyulureas.28 this issue should be investigated in detail in a real clinical setting. |
| PubMedID- 23264429 | Rather, an appropriate evaluation should beundertaken by a health care professional with expertise in diabetes to determinethe cause of the low blood glucose, the circumstances of the episode, whether itwas an isolated incident, whether adjustment to the insulin regimen may mitigatethis risk, and the likelihood of such an episode happening again. |
| PubMedID- 25892459 | diabetes was significantly associated with neonatal hypoglycemia (or=3.53 95%ci=2.87–4.34). |
| PubMedID- 23926399 | In type 1 diabetes,especially with recurrent hypoglycemia, the action of icrhs in response to hypoglycemicstimulation is decreased (2, 3). |
| PubMedID- 20920434 | Conclusions: this article offers, for the first time, a method for smoothly reducing insulin delivery rate to prevent hypoglycemia in individuals with type 1 diabetes mellitus based on a mathematically formal assessment of hypoglycemic risk. |
| PubMedID- 22234148 | Moreover, in another case, a 54-year-old woman who had ra and type ii diabetes experienced periods of severe hypoglycemia hours after receiving etanercept injections [11]. |
| PubMedID- 22018449 | Objective: we identified risk factors for hypoglycemia hospitalization in patients with type 2 diabetes treated with oral antidiabetic drugs (oads). |
| PubMedID- 20876723 | Thus, the glucose counterregulatory defense against hypoglycemia in individuals with diabetes becomes impaired at almost every level and rendered even more defective through intensive insulin therapy. |
| PubMedID- 24451308 | [70] found that a gfd reduced gastrointestinal symptoms in the short term and particularly episodes of severe hypoglycemia in children with type i diabetes with cd; however, there were no changes in the standard deviation scores for height, weight, bmi, or the average hba1c before and after gfd consumption. |
| PubMedID- 25886514 | Patients with: known monogenic diabetes, acute complications of diabetes (severe hypoglycaemia, diabetic ketoacidosis – defined according to international society of pediatric and adolescent diabetes guidelines 2014 [14,15]), ongoing infectious disease or children treated with lipid-lowering or non-steroid anti-inflammatory agents were excluded from the study group. |
| PubMedID- 20633252 | The authors conclude that future interventions should target both parental fear and appropriate ways to prevent hypoglycaemia in children with type 1 diabetes [28]. |
| PubMedID- 23748506 | Background and aim: exenatide is a glucagon-like peptide-1 receptor agonist demonstrated to improve glycemic control with low hypoglycemia risk in patients with type 2 diabetes mellitus. |
| PubMedID- 24103902 | A retrospective case-note audit was carried out in adult type 1 diabetes patients with ongoing problematic hypoglycemia leading to limitation in daily activities and iah (gold score [a likert linear analog scale in which patients are asked to score between 1 and 7, respectively, if they are always aware or never aware of the onset of hypoglycemia] >4) (4) despite structured education with or without continuous subcutaneous insulin infusion (csii), who then used cgm in addition to csii or multiple daily injection (mdi) for at least 12 months. |
| PubMedID- 26046236 | Changes in hba1c, insulin dose and incidence of hypoglycemia in patients with type 1 diabetes after switching to insulin degludec in an outpatient setting: an observational study. |
| PubMedID- 21800022 | Adrenergic responses to hypoglycemia in patients with long-standing diabetes are often severely blunted and nonspecific neuroglycopenic symptoms tend to predominate. |
| PubMedID- 25135285 | The choice of drugs depends largely on the individual, including stage and duration of diabetes, problems with hypoglycemia and weight gain, comorbidities, fasting hyperglycemia versus postprandial hyperglycemia, insulin resistance versus insulin deficiency, and the patient’s preference are key parameters for the decision (fig. |
| PubMedID- 21701633 | Pieber et al27 compared glycemic control and risk of hypoglycemia in patients with type 1 diabetes randomized to either twice-daily insulin detemir or once-daily insulin glargine injections, in combination with premeal aspart to demonstrate noninferiority. |
| PubMedID- 24026211 | Other sglt2 inhibitors, dapagliflozin and empagliflozin, have also demonstrated efficacy in lowering hba1c and body weight with a low risk of hypoglycaemia in patients with type 2 diabetes [11–14]. |
| PubMedID- 20236369 | A common cause of hypoglycaemia in people with type 2 diabetes is glucose-lowering medication, in particular, those which raise insulin independently of ambient glucose concentration such as sulphonylureas and exogenous insulin. |
| PubMedID- 20536956 | Case report: a 27-year-old man with type 1 diabetes suffered an episode of nocturnal hypoglycaemia which provoked a tonic-clonic seizure. |
| PubMedID- 21917871 | Objective: we hypothesized that opioid receptor blockade with naloxone during antecedent hypoglycemia in patients with type 1 diabetes mellitus (t1dm) would prevent the development of haaf. |
| PubMedID- 20587723 | Thus, at least two separate mechanisms for increasing thrombosis are activated by hypoglycemia in individuals with type 1 diabetes and healthy individuals. |
| PubMedID- 26150733 | More patients on diabetes medications with recent hypoglycemia reported interference with social activities in the previous 4 weeks compared to patients who never had hypoglycemia. |
| PubMedID- 20332355 | Objective: to minimize hypoglycemia in subjects with type 1 diabetes by automated glucagon delivery in a closed-loop insulin delivery system. |
| PubMedID- 21868778 | These data suggest that lgs has the potential to reduce nocturnal hypoglycemia in patients with type 1 diabetes at the highest risk. |
| PubMedID- 21404489 | In 15 subjects (21 implantations) the main indication was extremely instable course of diabetes due to the hypoglycaemia unawareness syndrome. |
| PubMedID- 26025695 | We describe a type 2 diabetes patient with persistent hypoglycemia caused by sulfonylurea misuse on top of a dpp-4 inhibitor. |
| PubMedID- 22748821 | Background: addition of a sulphonylurea to metformin improves glycaemic control in type 2 diabetes, but is associated with hypoglycaemia and weight gain. |
| PubMedID- 26399329 | These experimental findings explain why memory, learning, intelligence and attention are the cognitive domains most vulnerable to hypoglycemia in children with type 1 diabetes [8, 9]. |
| PubMedID- 22837906 | The effect of fasting during ramadan on rates of hypoglycemia in patients with diabetes is not known with certainty. |
| PubMedID- 24574352 | We asked: 1) what are the acute, temporal associations between mvpa and hypoglycemia in adolescents with type 1 diabetes and 2) are these associations moderated by sex, fitness, or adiposity? |
| PubMedID- 24843771 | Dapagliflozin added to metformin for 102 weeks resulted in sustained reductions in hba1c, fasting blood glucose and weight without increased risk of hypoglycemia in patients with type 2 diabetes inadequately controlled by metformin alone47. |
| PubMedID- 22234990 | Conclusions: medications should be prescribed carefully for patients at high risk of hypoglycemia, particularly those with diabetes complications or those taking insulin alone or in combination. |
| PubMedID- 26163815 | In both type 1 and type 2 diabetes, recurrent episodes of treatment-associated hypoglycemia impair how well the brain can sense and respond to subsequent episodes of hypoglycemia. |
| PubMedID- 22768352 | hypoglycemia in patients without diabetes has many potential causes [1]–[13], one of which is the malicious administration of insulin [14]–[19]. |
| PubMedID- 22155651 | Also, recurrent hypoglycemia in diabetes exacerbates the hippocampal dysfunction induced by diabetes, which has clinical significance in diabetes therapy. |
| PubMedID- 24122616 | The performance of the proposed r-bbnn algorithm was evaluated by an application to the field of medical diagnosis using real hypoglycemia episodes in patients with type 1 diabetes mellitus. |