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PedAM

Pediatric Disease Annotations & Medicines




Disease hypoglycemia
Phenotype |diabetes
Sentences 306
PubMedID- 22363495 Therefore, since retina glycogen serves as an energy reservoir, under the hypoglycemia observed clinically in patients with type-1 diabetes, retinal neuronal function must be seriously compromised.
PubMedID- 26407587 Conclusions: nocturnal hypoglycemia in patients with type 2 diabetes caused a decrease in awakening response in the 4-8-h period following the event.
PubMedID- 25782322 It is concluded that evaluation of quality of life and hypoglycemia-related symptoms in patients with type 2 diabetes mellitus on basal-bolus insulin therapy allows for comprehensive estimation of the effectiveness of therapy on an individual basis.
PubMedID- 22449098 Conclusion: this single-arm study suggested that switching to insulin glargine plus oads significantly improved glycaemic control, with a low incidence of hypoglycaemia, in patients with type 2 diabetes uncontrolled on premixed insulin plus oads.
PubMedID- 23256228 Systematic Review of the Evidence We conducted the current review to provide broader insight into the incidence of, the risk factors for, and the clinical and social impact of severe hypoglycemia in adults with type 2 diabetes treated with glucose lowering medications.
PubMedID- 25779865 Aims: accurate assessment of blood glucose fluctuation is essential for managing blood glucose control while avoiding hypoglycemia in patients with diabetes mellitus.
PubMedID- 22074724 Exclusion criteria included the following: type 1 diabetes, history of severe hypoglycemia within the past 2 years, known or suspected end-stage liver disease, cardiogenic shock at presentation, documented pregnancy, life expectancy of <90 days, anticipated poor adherence or loss to follow-up, and prior enrollment in this trial or current enrollment in another trial of ami.
PubMedID- 22784848 Population-based study of hypoglycemia in patients with type 1 diabetes mellitus requiring emergency medical services.
PubMedID- 22187477 Rather, an appropriate evaluation should beundertaken by a health care professional with expertise in diabetes to determinethe cause of the low blood glucose, the circumstances of the episode, whether itwas an isolated incident, whether adjustment to the insulin regimen may mitigatethis risk, and the likelihood of such an episode happening again.
PubMedID- 23063035 Background: self-monitoring of blood glucose (smbg) and continuous glucose monitoring (cgm) have been proven effective in improving hemoglobin a1c (hba1c) and in reducing hypoglycemia in patients with type 1 diabetes mellitus (t1dm).
PubMedID- 26229480 hypoglycemia hospitalization frequency in patients with type 2 diabetes mellitus: a comparison of dipeptidyl peptidase 4 inhibitors and insulin secretagogues using the french health insurance database.
PubMedID- 21188352 Melatonin decreases insulin sensitivity, can decrease insulin secretion and can increase blood glucose levels, while phototherapy sessions (which potentially decrease melatonin levels) have been shown to induce recurrent hypoglycaemia in a patient with type 1 diabetes [24–26].
PubMedID- 24083163 [157] it may be considered a first-line treatment for severe hypoglycemia in patients with diabetes treated on insulin.
PubMedID- 21193736 hypoglycemia in diabetes is fundamentally iatrogenic, the result of therapeutic hyperinsulinemia caused by treatment with a sulfonylurea, a glinide, or insulin.
PubMedID- 24123789 The beta-cell replacement by islet transplantation is an attractive approach for normalizing blood glucose without hypoglycaemia in patient with type 1 diabetes mellitus (t1d).
PubMedID- 21246006 For this reason, the american association of clinical endocrinologists has recommended the use of personal devices for glucose control and prevention of hypoglycemia in patients with type 1 diabetes [2,3] and pregnancy with diabetes [4,5].
PubMedID- 26173655 Conclusions: caffeine intake should be considered as another strategy that may modestly attenuate hypoglycaemia in individuals with type 1 diabetes during exercise, but should be taken with precautionary measures as it may increase the risk of late-onset hypoglycaemia.
PubMedID- 23859434 Real-world rates, predictors, and associated costs of hypoglycemia among patients with type 2 diabetes mellitus treated with insulin glargine: results of a pooled analysis of six retrospective observational studies.
PubMedID- 23391679 hypoglycemia in patients with diabetes who are fasting for laboratory blood tests: the cape girardeau hypoglycemia en route prevention program.
PubMedID- 24654672 It has been estimated that the incidence rate for emergency treatment of severe hypoglycaemia in people with type 1 diabetes is ˜11.5 per 100 patients-years 11. in that study, the associated cost was estimated to be ˜£6.5 m across the uk.
PubMedID- 26248501 hypoglycaemia in adults with insulin-treated diabetes in the uk: self-reported frequency and effects.
PubMedID- 26287419 diabetes with history of severe hypoglycemia group (dwh) and diabetes without history of severe hypoglycemia group (dwoh) were selected from the patients with diabetes.
PubMedID- 20061360 Estimates of the incidence of severe hypoglycaemia in patients with type 2 diabetes vary, depending on definitions and methods of ascertainment.
PubMedID- 23835337 Indeed, 6–10% of deaths in young people with type 1 diabetes are directly attributable to hypoglycemia (15–17).
PubMedID- 22723582 Allogeneic islet transplantation offers a minimally invasive option for β-cell replacement in people with type 1 diabetes complicated by recurrent severe hypoglycemia and/or marked glycemic lability.
PubMedID- 21617112 Furthermore, the management of type 2 diabetes can be complicated by hypoglycemia, which can seriously limit the pursuit of glycemic control.
PubMedID- 22291471 For patients with type 2 diabetes mellitus, the incidence of severe hypoglycemia was 0.3 (median) episodes per 100 person-years for insulin analogs and 1.4 for human regular insulin.
PubMedID- 23704685 Airas were generally responsible for rapidly progressive insulin-resistant diabetes, sometimes associated with spontaneous hypoglycemia with hyperinsulinemia that could be due to an impairment of insulin degradation (3,4).
PubMedID- 24683833 [diagnosis and assessment of hypoglycemia in patients with diabetes mellitus].
PubMedID- 21437091 Thus, guidelines that avoid the use of oral antidiabetes agents associated with hypoglycemia and weight gain (eg, aace/ace algorithm) are more logical and becoming increasingly popular in treating patients with diabetes, even perioperatively.
PubMedID- 26450431 Although centrally acting sympatholytics have some beneficial effects in clinics [44, 45], these drugs are nonspecific and limited by their adverse effects on insulin resistance and an unawareness of hypoglycaemia in patients with diabetes [45].
PubMedID- 24147203 Glucagon-like peptide-1 (glp-1) receptor agonists result in greater improvements in glycemic control than placebo and promote weight loss with minimal hypoglycemia in patients with type 2 diabetes mellitus.
PubMedID- 24013981 Patients with longer-duration diabetes had increased risks of symptomatic hypoglycemia, confirmed hypoglycemia (self-monitored blood glucose <50 mg/dl and <70 mg/dl), and nocturnal hypoglycemia (all p<.001).
PubMedID- 22187469 A large cohort study suggested that among older adults with type 2 diabetes, a history of severe hypoglycemia was associated with greater risk of dementia (200).
PubMedID- 21892855 Objective: the objective of this study was to examine the frequency of hypoglycemia among patients with type 2 diabetes who had concomitantly used exenatide bid (exenatide) and long-acting insulin and continued this combination vs those who continued long-acting insulin alone.
PubMedID- 19703761 Incidence of severe nocturnal hypoglycemia in patients with type 1 diabetes treated with insulin lispro or regular human insulin in addition to basal insulin glargine.
PubMedID- 20546285 Frequency of biochemical hypoglycaemia in adults with type 1 diabetes with and without impaired awareness of hypoglycaemia: no identifiable differences using continuous glucose monitoring.
PubMedID- 23781301 Association of igf1 with glycemic control and occurrence of severe hypoglycemia in patients with type 1 diabetes mellitus.
PubMedID- 24459413 Brain atrophy, particularly microstructural hippocampal alterations seen using diffusion tensor imaging, has been associated with diabetes, independent of vascular lesions.56 hypoglycemia due to insulin therapy may also lead to structural brain damage and memory impairments in patients with type 1 diabetes.57 the possible relationship between pathological glucose tolerance and ad has been under investigation.
PubMedID- 21102380 Results: the rate of major hypoglycemia decreased in patients with type 1 diabetes--the incidence rate ratio (irr) was 0.14 for daytime and 0.03 for nocturnal episodes (p <0.0001) and did not change in patients with type 2 diabetes.
PubMedID- 25325279 Optimal candidates for the switch from glimepiride to sitagliptin to reduce hypoglycemia in patients with type 2 diabetes mellitus.
PubMedID- 23402452 hypoglycemia is common in patients with diabetes, and any severe hypoglycemic event can increase the fear of future hypoglycemic events.
PubMedID- 20164212 The mechanism underlying the biphasic phenotype of neonatal hypoglycemia with later diabetes is not known.
PubMedID- 22047939 The effect of short-term use of the guardian rt continuous glucose monitoring system on fear of hypoglycaemia in patients with type 1 diabetes mellitus.
PubMedID- 26003888 Incidence of hypoglycemia in patients with type 2 diabetes treated with gliclazide versus dpp-4 inhibitors during ramadan: a meta-analytical approach.
PubMedID- 25698911 Thus, the aim of the current analysis was to investigate the rates and predictors of documented hypoglycemia in patients with type 2 diabetes on various insulin treatment regimens in general and internal medicine practices.
PubMedID- 25282010 In trials in type 2 diabetes, rates of nocturnal hypoglycemia were lower with insulin degludec than with insulin glargine, and more flexible; once-daily dose timing was shown to be possible.
PubMedID- 25192953 Although hypoglycemia in patients with diabetes is mostly iatrogenic and is mainly caused by glucose-lowering agents, such as insulin and sulfonylureas, hypoglycemia in patients without diabetes can be caused by many factors including malnutrition, alcohol abuse, hepatic failure, and sepsis [9].
PubMedID- 25305751 This article summarizes our current knowledge of the epidemiology, pathogenesis, and morbidity of hypoglycemia in patients with diabetes and chronic kidney disease and reviews therapeutic considerations in this situation.
PubMedID- 23323805 The incidence of hypoglycaemia in patients with and without diabetes was quantified.

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