PedAM
Pediatric Disease Annotations & Medicines
| Disease | neuropathy |
| Phenotype | |diabetes |
| Sentences | 212 |
| PubMedID- 23340890 | Over the last 30 years, a marked improvement in diabetic nephropathy, retinopathy, and neuropathy was observed in patients with type 1 diabetes mellitus (t1dm) (1–3). |
| PubMedID- 21507498 | Aims: to test autoantibodies from subsets of diabetes with painful neuropathy, maculopathy and nephropathy for effects in neurons. |
| PubMedID- 24565211 | Aims: this study aimed to assess the prevalence and electrophysiological features of ulnar entrapment neuropathy in patients with type 2 diabetes mellitus (dm). |
| PubMedID- 22209024 | The purpose of this pilot study was to investigate a possible role for gap-43 in the detection of the early stages of small-fiber neuropathy in patients with type 2 diabetes mellitus (dm2) as compared with a well- established and validated parameter - intra-epidermal nerve fiber density (ienfd) of protein gene product 9.5 (pgp 9.5) immunoreactive intra-epidermal c fibers. |
| PubMedID- 23983297 | [9] diabetes is associated with peripheral neuropathy, so the nerve may already be functionally abnormal at the time of intubation, and this may worsen thereafter resulting in cord dysfunction. |
| PubMedID- 26264399 | We therefore performed a proof-of-concept pilot study to evaluate the effect of exenatide, a glp-1 agonist, on measures of dpn and cardiovascular autonomic neuropathy (can) in patients with type 2 diabetes (t2d). |
| PubMedID- 24009454 | Considering the beneficial therapeutic effects of antioxidants, such as alphalipoic acid, on peripheral neuropathy associated with diabetes [8,9], we hypothesized that vve may also be beneficial for treating peripheral nerve damage in prediabetes or early type 2 diabetes. |
| PubMedID- 24003572 | Non-healing foot ulcers in diabetes may be due to peripheral neuropathy and/or vasculopathy. |
| PubMedID- PMC4442996 | Diseases in which the availability of no is reduced include severe diabetes with neuropathy and endothelial dysfunction, metabolic syndrome, and down-regulation or deactivation of no synthase (nos) expression, which can occur in denervation of the erectile tissue after rp, atherosclerosis, advanced age, and hypogonadism [2]. |
| PubMedID- 24803311 | Enhanced glucose control is much more effective at preventing neuropathy in patients with type 1 diabetes than in those with type 2 disease [corrected]. |
| PubMedID- 21616974 | Ten subjects with diabetes mellitus complicated by neuropathy and 10 healthy controls underwent 3 mm distal thigh punch skin biopsies to create an intracutaneous excision axotomy followed by a concentric 4-mm overlapping biopsy at different time points. |
| PubMedID- 20148083 | Peripheral neuropathy affects patients with diabetes as well as patients that have impaired glucose tolerance and are considered to be prediabetic [1–5]. |
| PubMedID- 21256797 | Nonlinear pd2i heart rate complexity algorithm detects autonomic neuropathy in patients with type 1 diabetes mellitus. |
| PubMedID- 24228139 | In addition, patients with diabetes mellitus (dm) complicated by cardiovascular autonomic neuropathy may develop abnormalities in heart rate control with central and peripheral vascular dysfunction [10]. |
| PubMedID- 24843783 | In the present study, serum adiponectin levels were significantly higher in type 2 diabetes patients with neuropathy and retinopathy, but significantly lower in those with nephropathy. |
| PubMedID- 23258907 | Ccm has been shown to be effective as a rapid, noninvasive, repeatable evaluation that allows detection of neuropathy in patients with diabetes (10). |
| PubMedID- 24353617 | A questionnaire including age, sex, bmi, diabetes duration, type of treatment, hba1c, deformity, neuropathy symptoms, vascular symptoms, history of foot ulcer, previous training regarding foot care, smoking, history of retinopathy and nephropathy was completed for all patients. |
| PubMedID- 24552681 | Quantitative evaluation of microvascular dysfunction in peripheral neuropathy with diabetes by indocyanine green angiography. |
| PubMedID- 25315630 | Cobalamin status and its relation with depression, cognition and neuropathy in patients with type 2 diabetes mellitus using metformin. |
| PubMedID- 22618770 | The incidence of diabetic neuropathy increases with duration of diabetes, affecting up to 50% of diabetic patients after 25 years of disease (2). |
| PubMedID- 25520564 | The studied patients were grouped into: (1) diabetic control group (dc), which included 37 patients who had diabetes without neuropathy or ulceration and mnds neuropathy group (dn), which included 33 patients who had diabetes with neuropathy and mnds >2, without current or a history of ulceration; and (3) diabetic ulcer group (du), which included 30 patients who had diabetes and current ulceration, seven of those patients also gave a history of ulceration. |
| PubMedID- 22507446 | Participants were eligible if they had types 1 or 2 diabetes (with peripheral sensory neuropathy) or were healthy and did not have diabetes (with no sensory neuropathy) and between the ages of 40 and 75 years. |
| PubMedID- 19716319 | Effects of epalrestat, an aldose reductase inhibitor, on diabetic peripheral neuropathy in patients with type 2 diabetes, in relation to suppression of n(varepsilon)-carboxymethyl lysine. |
| PubMedID- 26435536 | This report focuses on the determining the burden of peripheral arterial disease and neuropathy in persons with diabetes mellitus (dm). |
| PubMedID- 22482054 | For example, diabetes can lead to peripheral neuropathy, and diabetic patients with pre-existing nerve damage may be predisposed to more severe forms of capn [2–4]. |
| PubMedID- 24926262 | Significant past medical history includes hypertension, diabetes with neuropathy and severe retinopathy leading to visual impairment, and cerebrovascular disease. |
| PubMedID- 23641349 | Tight glucose control can reduce neuropathy in patients with type 1 diabetes, but it is not as effective in patients with type 2 diabetes. |
| PubMedID- 26241393 | Purpose: we investigated the relationship between corneal subbasal nerve (sbn) plexus density, corneal sensitivity, and peripheral and cardiac autonomic neuropathy in patients with type 1 diabetes mellitus. |
| PubMedID- 21113297 | Alternatively, sleep may markedly increase central blood pressure in diabetes with neuropathy and facilitate the development of lvh. |
| PubMedID- 21873064 | Gait pattern alterations in older adults associated with type 2 diabetes in the absence of peripheral neuropathy--results from the baltimore longitudinal study of aging. |
| PubMedID- 26106229 | Small fiber neuropathy in patients with latent autoimmune diabetes in adults. |
| PubMedID- 23002037 | In type 1 diabetes the development of diabetic neuropathy has been related not only to glycemic control but also to conventional cardiovascular risk factors such as hypertension and lipids (30). |
| PubMedID- 25810640 | The mean frequencies of nuclear aberrations per cell in diabetes patients with neuropathy and without neuropathy were 0.02 +/- 0.02 and 0.01 +/- 0.01, respectively. |
| PubMedID- 23818897 | Epidemiologic studies have identified the duration and severity of hyperglycemia as major risk factors for the development of diabetic neuropathy in patients with diabetes [9, 10]. |
| PubMedID- 26496307 | Cardiovascular risk factors increase the risks of diabetic peripheral neuropathy in patients with type 2 diabetes mellitus: the taiwan diabetes study. |
| PubMedID- 24466465 | Diabetic bladder dysfunction may be induced by diabetic neuropathy and/or diuresis associated with diabetes [28,29]. |
| PubMedID- 24381887 | diabetes with peripheral neuropathy have more incidence of delayed bera tracing. |
| PubMedID- 24949485 | Diabetic gastroparesis (dg) affects patients with long-standing diabetes mellitus usually complicated by retinopathy, neuropathy, and nephropathy [1]. |
| PubMedID- 19674919 | Bladder dysfunction in diabetes is attributable to diabetic neuropathy that induces sensory and autonomic nerve dysfunction. |
| PubMedID- 25623477 | Three out of five patients were positive for longstanding history of type 2 diabetes mellitus with diabetic peripheral neuropathy and previous lower extremity amputations in the foot. |
| PubMedID- 22894640 | They showed that omega-3 fatty acids could attenuate the severity of neuropathy in patients with type 2 diabetes mellitus [13,15]. |
| PubMedID- 21472496 | Asymptomatic small fiber neuropathy in diabetes mellitus: investigations with intraepidermal nerve fiber density, quantitative sensory testing and laser-evoked potentials. |
| PubMedID- 25793613 | Compared with controls patients with depressive mood and mci were older, female, single, less educated, had more often past smoking status, had less physical activity, higher bmi, a longer duration of diabetes, more were diagnosed with neuropathy, retinopathy, hiperlipidemia and other co-morbidities, had a history of hypoglycemia and were treated with insulin. |
| PubMedID- 21816974 | diabetes, especially when complicated by neuropathy and foot ulcers, is a known contributing factor that increases the risk for postoperative infection after foot and ankle surgery (1). |
| PubMedID- 20624170 | Materials and methods: the sensitivity and evoked brain potentials (eps) to electrical oesophageal and median nerve stimulations were assessed in 14 type-1 diabetes patients with autonomic neuropathy and gi symptoms using a hyperinsulinaemic clamp at 6 and 15 mm. |
| PubMedID- 21341457 | Aim: to study clinical and metabolic risk factors for cardiovascular autonomic neuropathy in patients with type 2 diabetes mellitus (t2dm). |
| PubMedID- 22269030 | Conclusions: inferior quadrant retinal nerve fibre layer thinning is associated with peripheral neuropathy in patients with type 2 diabetes, and is more pronounced in those at higher risk of foot ulceration. |
| PubMedID- 23964895 | Differences in skin microcirculation on the upper and lower extremities in patients with diabetes mellitus: relationship of diabetic neuropathy and skin microcirculation. |
| PubMedID- 26501875 | [5] this degree of productivity loss for rls patients is similar to reports of productivity loss for diabetes with neuropathy, or bipolar disorder, and is thought to relate to rls-associated sleep disturbances. |
| PubMedID- 21180031 | diabetes mellitus (dm) due to autonomic neuropathy leads to asymptomatic cad. |