PedAM
Pediatric Disease Annotations & Medicines
| Disease | neuropathy |
| Phenotype | |diabetes |
| Sentences | 212 |
| PubMedID- 22669736 | Furthermore, it is thought that chronic repetitive ischaemia may induce long-term sympathetic nerve dysfunction.25 these mechanisms also ensure that in the early stages of coronary artery disease or during frequent vasospastic events, sympathetic neurons can be affected without the presence of obvious perfusion defects.11,22,26 this heterogenic cardiac sympathetic innervation, in otherwise viable myocardium, is thought to be the source of electrical instability which is associated with the development of ventricular arrhythmias.12,27 the role of spect i-123 mibg imaging in ischaemic heart disease and ventricular arrhythmias is therefore mainly focused on describing the regional sympathetic innervation status and detecting areas with perfusion/innervation mismatch.10,28 cardiac autonomic neuropathy (can) in patients with diabetes mellitus, on the other hand, is associated with regional hyperactivity of the sympathetic nervous system, resulting in an electrical instability.8,29 it is recognized that planar i-123 mibg imaging is useful to detect can and provide prognostic information on future cardiac events.30-32 however, planar indices are less sensitive in detecting small regional abnormalities which are often associated with diabetic neuropathy. |
| PubMedID- 23818901 | Common example is sensory neuropathy in patients with diabetes mellitus. |
| PubMedID- 20920366 | Indices of cardiovascular autonomic neuropathy also deteriorate with diabetes duration and shifts of the sympathovagal balance might in part account for vascular dysfunction [11], as our data suggest. |
| PubMedID- 24009302 | Higher systemic levels of c-reactive protein and sicam-1 have been associated with painful compared with painless neuropathy in patients with diabetes (10), but a detailed investigation of this association was not the focus of the current study. |
| PubMedID- 24651803 | It has been demonstrated that 1-deoxysls are cytotoxic in various model systems, and more important, they are implicated in the pathology of neuronal functional impairment in hereditary sensory and autonomic neuropathy in patients with type 1 diabetes (hsan1) (10). |
| PubMedID- 25899758 | The hallux, as opposed to the fifth metatarsal head, is a more sensitive indicator of neuropathy in patients with diabetes [42]. |
| PubMedID- 24629408 | Methods: the landmark study is a 4-year, two-site, natural history study of three participant groups: type 1 diabetes with neuropathy (t1w), type 1 diabetes without neuropathy (t1wo) and control participants without diabetes or neuropathy. |
| PubMedID- 22004301 | Conclusions: chemosensitivity to hypercapnia was depressed in patients with diabetes mellitus, irrespective of autonomic neuropathy, in comparison with control subjects. |
| PubMedID- 22346190 | Materials and methods: eighty four patients with type 2 diabetes mellitus (51 of them had neuropathy) and 31 apparent healthy subjects were studied in the unit of neurophysiology at the university hospital of medical college, al-nahrin university in baghdad, iraq. |
| PubMedID- 21303632 | Background: cardiovascular autonomic neuropathy (can) is associated with diabetes and may be related to the development of hypertension, ischemic stroke, and a number of other late complications. |
| PubMedID- 21727664 | This study was carried out to evaluate the usefulness of simple bed side screening modalities for peripheral neuropathy in patients with diabetes mellitus. |
| PubMedID- 21822421 | Exocrine pancreatic insufficiency in diabetes mellitus: a complication of diabetic neuropathy or a different type of diabetes. |
| PubMedID- 24719137 | The role of insulin resistance in diabetic neuropathy in koreans with type 2 diabetes mellitus: a 6-year follow-up study. |
| PubMedID- 22291497 | Despite compliance, the patient developed corticosteroid-induced diabetes mellitus with lower extremity neuropathy and was unable to work due to painful lower extremity ulcerative lesions requiring opioid analgesia. |
| PubMedID- 20411258 | Cardiac autonomic neuropathy in patients with diabetes and no symptoms of coronary artery disease: comparison of 123i-metaiodobenzylguanidine myocardial scintigraphy and heart rate variability. |
| PubMedID- 24295032 | In this sample of patients with type 2 diabetes, pad was associated with autonomic neuropathy, as evaluated both by conventional cardiovascular autonomic function tests and hrv indices. |
| PubMedID- 22396832 | diabetes mellitus with peripheral sensory neuropathy frequently results in forefoot ulceration. |
| PubMedID- 24705616 | However, the peripheral neuropathy associated with diabetes masks symptoms of atherosclerosis, making the true prevalence of disease in the peripheral arteries difficult to ascertain without additional testing and presenting a challenge to early identification and prevention of disease progression (12,17). |
| PubMedID- 26285034 | Strict glycemic control has been proven to delay the onset and slow the progression of diabetic retinopathy, nephropathy, and neuropathy in patients with diabetes mellitus (dm) [1, 2]. |
| PubMedID- 21514610 | Introduction: melas syndrome (mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes) is a rare genetic mitochondrial disease which can cause cerebral (cerebrovascular accident, migraine, mental deterioration..), sensorial (bilateral symmetrical deafness) and peripheral (muscular involvement, neuropathy) disorders potentially associated with diabetes, renal or cardiac disorders, or growth retardation. |
| PubMedID- 21911773 | There are no studies examining neuropathy in patients with type 1 diabetes and cd or the effect of a gfd. |
| PubMedID- 25387363 | Although erythropoietin ameliorates experimental type 2 diabetes with neuropathy, serious side effects limit its potential clinical use. |
| PubMedID- 22168362 | Distal symmetrical sensory neuropathy in diabetes involves the dying back of axons, and the pathology equates with axonal dystrophy generated under conditions of aberrant ca2+ signalling. |
| PubMedID- 21350409 | We revealed the high risk of the development of diabetic cardiac autonomic neuropathy in children with diabetes mellitus type i in the presence of the autonomic dysfunction syndrome. |
| PubMedID- 21503386 | Background: the presence of cardiac autonomic neuropathy (can) in patients with diabetes mellitus (dm) is associated with increased mortality and chronic microvascular complications of diabetes. |
| PubMedID- 25395956 | All subjects recruited in this study were divided into dm (diabetes without neuropathy, retinopathy or nephropathy), dpn (diabetes with peripheral neuropathy only) and healthy control groups. |
| PubMedID- 23882058 | These data thus suggested that glucose variability may be important in the development of peripheral neuropathy in patients with type 1 diabetes and that the nervous system may be particularly vulnerable to glycemic variability (9). |
| PubMedID- 24874311 | Objective: to investigate parameters of insulin resistance and arterial stiffness in different stages of cardiovascular autonomic neuropathy in patients with diabetes mellitus type 2 (dm2). |
| PubMedID- 21095715 | It has been well documented that subjects with peripheral neuropathy resulting from diabetes mellitus are at high risk of developing foot ulceration. |
| PubMedID- 20876709 | It is known that similar patterns of neuropathy occur in patients without diabetes (2). |
| PubMedID- 22331979 | We performed a systematic review of the literature to evaluate the effects of alpha lipoic acid for symptomatic peripheral neuropathy in patients with diabetes mellitus. |
| PubMedID- 25410213 | Diabetic radiculoplexus neuropathies (drpn) are neuropathies clinically and pathologically distinct from the neuropathy typically associated with diabetes (dpn). |
| PubMedID- 26344697 | Aims: this paper aims to investigate whether intraepidermal nerve-fibre density (ienfd) may be used as a marker of the course of neuropathy in patients with type 2 diabetes mellitus. |
| PubMedID- 21687738 | The consequence of deficiency on frataxin is that patients have progressive gait and limb ataxia, slurred speech, and peripheral axonal neuropathy associated with hypertrophic cardiomyopathy, diabetes mellitus or glucose intolerance and skeletal deformities. |
| PubMedID- 22642973 | The present study aims to describe the community prevalence, patterns and predictors of distal peripheral neuropathy among patients with diabetes mellitus in sri lanka with a view of identifying differential risk factors, which may lead to improved preventive measures and care for diabetic patients in the south asia region. |
| PubMedID- 25692057 | It is seen most commonly in the foot and ankle secondary to peripheral neuropathy associated with diabetes mellitus. |
| PubMedID- 23465172 | Conclusions: mitochondrial oxidative phosphorylation is impaired only in type 2 diabetes mellitus patients with neuropathy whether or not peripheral arterial disease is present and is associated with the increased proinflammatory state observed in these groups. |
| PubMedID- 23466181 | Autonomic neuropathy was associated with diabetes impact. |
| PubMedID- 25672193 | Frequency of peripheral neuropathy in patients with diabetes mellitus. |
| PubMedID- 25623542 | Cardiovascular disease, obesity, kidney failure, diabetic retinopathy, and neuropathy are associated with type ii diabetes mellitus (t2dm). |
| PubMedID- 23983788 | Furthermore, acupuncture has been used encouragingly to treat peripheral neuropathy associated with diabetes and hiv [16–22]. |
| PubMedID- 20151233 | It is seen most commonly in the foot and ankle, secondary to peripheral neuropathy in patients with diabetes mellitus. |
| PubMedID- 26336610 | Reduced cough reflex and ability to bring out sputum due to associated autonomic neuropathy in patients with long-standing diabetes has been reported,1 but whether this was the case in our study subjects cannot be stated because we did not check for diabetic autonomic neuropathy. |
| PubMedID- 25579387 | Hyperuricemia was also significantly associated with increased risk of peripheral neuropathy in patients with type 2 diabetes (risk ratio [rr] = 2.83, 95%ci 2.13-3.76, p < 0.00001). |
| PubMedID- 20139661 | Autonomic neuropathy in diabetes leads to impaired regulation of blood pressure and heart rate variability (hrv), which is due to a shift in cardiac autonomic balance towards sympathetic dominance. |
| PubMedID- 23419424 | While neuropathy was associated with age and diabetes duration, no association was found with mean hba1c level. |
| PubMedID- 24490775 | Autonomic neuropathy in patients with diabetes and chronic kidney disease (ckd)[10]. |
| PubMedID- 23118788 | Among the papers, y. piao and x. liang contributed with an excellent review about neurological activity of traditional chinese medicine against diabetic peripheral neuropathy (dpn) associated with chronic diabetes mellitus that causes nerve degeneration while in another review article i. e. orhan summarized the literature relevant to neurobiological effects of centella asiatica “gotu kola,” a reputed plant used as brain tonic in ayurvedic medicine. |
| PubMedID- 24151985 | Conclusions: we did not find a significant relationship between presence of neuropathy in those with diabetes and poorer peripheral bone health. |
| PubMedID- 23404298 | Duration of diabetes was correlated with increasing neuropathy severity (r = 0.427; p < 0.001). |