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PedAM

Pediatric Disease Annotations & Medicines




Disease asthma
Phenotype |obesity
Sentences 111
PubMedID- 25859274 These results are similar to those of other studies that have clustered clinical, inflammatory and functional profiles pointing to a more symptomatic asthma associated with obesity in women [5,19].
PubMedID- 22742416 [4] showed that obesity was associated with asthma symptoms only in the least obstructed tertile, as measured by the ratio of fev1 (forced expired volume in one second) to fvc (forced vital capacity).
PubMedID- 23215875 Objective: the potential role of central obesity in asthma outcomes has been examined in a few studies.
PubMedID- 23636141 Examples of these phenotypes include early-onset mild allergic asthma, later-onset asthma associated with obesity, and severe non-atopic asthma with frequent exacerbations.
PubMedID- 22335609 Active smoking and obesity were positively associated with asthma without rhinitis.
PubMedID- 24204385 A number of cellular signaling and metabolism mechanisms could contribute to increased asthma risk in patients with obesity and/or metabolic syndrome.
PubMedID- 25914932 This article will discuss what we have learned about the immunological and pathophysiological basis of asthma in obesity from animal and human studies, and how this might guide therapy.
PubMedID- 26321758 Epidemiological studies associate obesity with onset of asthma, especially in obese children, suggesting obesity as the risk factor for asthma.
PubMedID- 21555716 An interaction between the associations of bmi and fat mass and obesity-associated (fto) genotype with asthma explained the different directions of the different estimates, and a simulation study supported the observation that msmm/mgmm estimators are negatively correlated with the other estimators when such an interaction is present.
PubMedID- 24899788 As osas and asthma are highly associated with obesity, inflammation, and lung injury, this may suggest the association of omentin and lung injury.
PubMedID- 26576744 Other studies have also identified a subset of asthmatics with obesity where distinct biological mechanisms may be driving disease severity [18–20].

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