PedAM
Pediatric Disease Annotations & Medicines
| Disease | epilepsy |
| Symptom | C0036572|seizure |
| Sentences | 162 |
| PubMedID- 25569746 | Different clinical phenotypes were identified, including generalized epilepsy with febrile seizure plus (gefs+), dravet syndrome, and partial epilepsy with febrile seizure plus (pefs+). |
| PubMedID- 22973215 | Therefore, validation of the present findings will be desirable in a sample of epilepsy patients with different seizure origins, as well as in ecog recordings from subjects with other neural pathologies, such as tumor patients, and confirmation of our results with non-invasive methods in healthy controls will be important. |
| PubMedID- 23248692 | The mutation identified in this patient is located in the pore-forming loop of scn1a and this case report suggests missense mutation in pore-forming loop causes generalized epilepsy with febrile seizure plus (gefs+) with clinically more severe neurologic phenotype including intellectual disabilities (mental retardation and autism features) and neuropsychiatric disease (anxiety disorder). |
| PubMedID- 25695076 | A potential biochemical mechanism that could adversely affect seizure threshold (in patients with epilepsy), particularly the effect of malnutrition on inhibitory neurotransmitter and electrolyte, has been worked out where supportive evidence from animal research and epidemiological findings in children has been discussed 6. |
| PubMedID- 26283660 | Nurses may need to be formally trained for seizure management due to high epilepsy rates in this population. |
| PubMedID- 24086344 | We investigated gene expression in the hypoxic seizure model of acquired epilepsy, a rodent model in which the progression to later life epileptic seizures has been previously described . |
| PubMedID- 20005953 | Basal ganglia are engaged in seizure propagation, control of seizures, and in epilepsy-induced neuroplasticity. |
| PubMedID- 24011985 | Interictal eeg findings of epilepsy with generalized tonic-clonic seizure only (egtcs) were reviewed for comparison. |
| PubMedID- 23621876 | The former are convincing cases of medically intractable epilepsy with good seizure control following hippocampal resection. |
| PubMedID- 26245188 | In our population post-ih was more frequently reported in patients on polytherapy, suggesting a severe epilepsy phenotype, and in patients with a higher seizure frequency (monthly/daily) suggesting that the seizures act as a trigger for headache attacks, as reported in literature . |
| PubMedID- 24273733 | Postoperative seizure outcome of neocortical epilepsy associated with focal cortical dysplasia (fcd) is poorer than that of epilepsy associated with hippocampal sclerosis or tumor (chung et al., 2005; jeong et al., 2012). |
| PubMedID- 24257433 | Genetic (generalized) epilepsy with febrile seizures plus is a familial epilepsy syndrome with marked phenotypic heterogeneity ranging from simple febrile seizure to severe phenotypes. |
| PubMedID- 26333582 | Background: aminophylline can trigger seizures in patients without known underlying epilepsy or added risk factor for seizure exacerbation in epilepsy. |
| PubMedID- 22837771 | New generation antiepileptic medications have improved seizure outcome in patients with intractable epilepsy and seem to be superior in tolerability when compared with conventional antiepileptic drugs (aeds). |
| PubMedID- 24497269 | Overall, resective epilepsy surgery leads to seizure freedom in approximately two thirds of patients with intractable temporal lobe epilepsy and about one half of individuals with focal neocortical epilepsy, although only the former observation is supported by class i evidence. |
| PubMedID- 25934584 | The metaphors identified by this research are a useful resource to better understand the seizure experiences of patients with epilepsy, helping to improve clinical treatment. |
| PubMedID- 21035403 | The majority of patients (76%) in this study had idiopathic generalized epilepsy, with a relative seizure risk of 4.0 (p=0.002) for patients deemed unfit to drive in this subgroup. |
| PubMedID- 25807126 | Shorter epilepsy duration is associated with better seizure outcome in temporal lobe epilepsy surgery. |
| PubMedID- 25803241 | Reported that pranlukast add-on therapy reduces seizure frequencies in patients with intractable partial epilepsy and that this effect possibly results from the pleiotropic effects, including normalization of matrix metalloproteinase-9 in sera, reduced leakage of pro-inflammatory cytokines into central nervous system, and inhibition of extravasation of leucocytes from brain capillaries . |
| PubMedID- 21555051 | We retrospectively reviewed charts for lacosamide use and seizure frequency outcome in patients with focal epilepsy (wilcoxon signed rank test). |
| PubMedID- 20169777 | Predictors of unfavourable seizure outcome in patients with epilepsy in nepal. |
| PubMedID- 25710040 | In , correlation dimension and five other features for seizure prediction of focal neocortical epilepsy produced reasonably good results with 90.2% for sensitivity and 97% for specificity. |
| PubMedID- 23029379 | Stress is the most commonly reported seizure precipitant in patients with epilepsy . |
| PubMedID- 23456771 | Treating seizures with higher epilepsy medication doses at times of greatest seizure susceptibility may relieve seizure burden. |
| PubMedID- 20880506 | This article reviews the information now available on the role of astrocytes in the hippocampal seizure focus in patients with temporal lobe epilepsy with hippocampal sclerosis. |
| PubMedID- 24165229 | However, bilateral acupuncture of taichon (lr3), hegu (li4) and baihui (gv20) acupoints did not significantly alter the frequency of seizure occurrence in patients with refractory epilepsy, indicating that acupuncture is not beneficial in patients with refractory epilepsy . |
| PubMedID- 22426353 | Electrical status epilepticus in sleep (eses)/continuous spikes and waves during slow sleep (csws) is an age-related, self-limiting disorder characterised by epilepsy with different seizure types, global or selective neuropsychological regression, motor impairment, and a typical eeg pattern of continuous epileptiform activity for more than 85% of non-rapid eye movement (nrem) sleep. |
| PubMedID- 22618127 | In this review we describe the genetic advances in progressive myoclonus epilepsies, which are strictly monogenic disorders, genetic generalized epilepsies, mostly exhibiting complex genetic inheritance, and scn1a-related phenotypes, namely genetic generalized epilepsy with febrile seizure plus and dravet syndrome. |
| PubMedID- 23904950 | The incidence of seizure activity in patients with epilepsy associated with anesthesia is 3.4% 2, but rse is rarely reported during emergence of anesthesia. |
| PubMedID- 24083132 | The physiological mechanisms that underlie the transition to seizure in epilepsy in humans are still largely unknown. |
| PubMedID- 26224066 | It is because the fact that a real shift of tonic-clonic seizure in epilepsy is generally accompanied by the transition of asynchronous activity to coherent oscillations, even if this transitional mechanism remains yet unknown. |
| PubMedID- 22213776 | Qol scores were assessed using the hass or ssq for seizure severity, quality of life in childhood epilepsy (qolce) for qol, and child behavior check list (cbcl) for behavior. |
| PubMedID- 24649466 | Antiepileptic drugs (aed) can be effective for seizure control in patients with epilepsy, but still about 30 % of them are suffering from medically refractory epilepsy.1 if aeds fail to control seizures, alternative treatment options, such as epilepsy surgery or ketogenic diet, can be considered. |
| PubMedID- 25826701 | Female reproductive hormones are known to have opposing effects on neuronal excitability and decrease the seizure frequency of catamenial type of epilepsy . |
| PubMedID- 21364890 | Used data-driven independent component analysis (ica) to investigate the alterations of the dmn in the mesial temporal lobe epilepsy with complex partial seizure . |
| PubMedID- 22003298 | In addition to seizure control, patients with epilepsy may have psychosocial symptoms requiring treatment. |
| PubMedID- 26420440 | A pharmacoresistent epilepsy with seizure onset from the right temporal lobe and declarative memory deficits were observed affecting primarily the recall of verbal informations. |
| PubMedID- 21035358 | Our results indicate that, like antiepileptic drugs, vns does not have such a good seizure-reducing effect in patients with epilepsy and learning disabilities compared with the general epilepsy population. |
| PubMedID- 24489129 | Mood, anxiety, and incomplete seizure control affect quality of life after epilepsy surgery. |
| PubMedID- 26255884 | Purpose: the purpose of this study was to measure health-care resource utilization and costs in treatment-adherent, previously seizure-free patients with epilepsy who were treated in the inpatient/emergency room (er) setting for new-onset seizures, compared with matched controls. |
| PubMedID- 25024183 | Haploinsufficiency of the voltage-gated sodium channel nav1.1 causes dravet syndrome, an intractable developmental epilepsy syndrome with seizure onset in the first year of life. |
| PubMedID- 22988325 | A limitation to this conclusion is that seizures in epilepsy result from lowered seizure threshold and antiepileptic drugs raise this seizure threshold. |
| PubMedID- 23046918 | Conclusions: vagus nerve stimulation therapy proved to be an alternative for the reduction of seizure frequency in patients with drug-resistant epilepsy who suffered disabling seizures despite undergoing corpus callosotomy as primary surgery. |
| PubMedID- 22972760 | Partial symptomatic or generalised idiopathic epilepsy were associated with greater seizure-freedom than partial cryptogenic disease. |
| PubMedID- 25383238 | epilepsy with variable seizure types develop later in childhood or adulthood. |
| PubMedID- 20623928 | It is not clear whether the behavioral changes that occur following seizures or with epilepsy may, for example: (i) arise from the epilepsy itself; (ii) may appear as a form of forced change induced by the seizure; (iii) might arise from reactive or released behaviors after the seizure (as a postictal phenomenon); or (iv) may be a comorbid psychiatric condition (which often occur in epilepsy). |
| PubMedID- 24405698 | Conclusions: results from this relatively small series provide evidence that vaccinations do not significantly affect clinical and cognitive evolution of dravet syndrome and generalized epilepsy with febrile seizure plus patients even if they carry scn1a mutations. |
| PubMedID- 24273709 | Surgical resection of the epileptogenic region is an effective therapy for individuals with medically refractory temporal lobe epilepsy, leading to seizure freedom in about two thirds of patients (foldvary et al., 2000; spencer and huh, 2008; sperling et al., 1996; wiebe et al., 2001). |
| PubMedID- 20863362 | Thus, our results suggest that ms contribution to epilepsy induction, together with seizure activity potentially favoring ms relapses, may create a positive feedback loop between the two disease conditions. |
| PubMedID- 23768201 | Also, lesional epilepsy was associated with better seizure outcomes than nonlesional epilepsy (or 1.34, 95% ci 1.19-1.49). |