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PedAM

Pediatric Disease Annotations & Medicines




Disease epilepsy
Symptom |seizure
Sentences 162
PubMedID- 23622191 Some types of experimental status epilepticus cause neuronal necrosis and apoptosis, and are followed by chronic epilepsy with spontaneous recurrent seizures, others appear relatively benign, so that seizure-induced neuronal injury and epileptogenesis are highly age-, seizure model-, and species-dependent.
PubMedID- 25225143 Objectives: this study was an assessment of the incidence, course, and etiology of epilepsy with vaccination-related seizure onset in a population-based cohort of children.
PubMedID- 22310062 Two children became seizure-free: one with focal epilepsy of unknown etiology and another with refractory childhood absence epilepsy.
PubMedID- 25903657 Temporal lobe epilepsy (tle) with seizure onset from the mesial temporal lobe structure is recognized as a syndrome of mesial temporal lobe epilepsy (mtle) and it comprises the majority of cases of epilepsy refractory to pharmacotherapy 4.
PubMedID- 24109474 Studied the effects of 12 months of oxcarbazepine (oxc) monotherapy on seizure control in patients with brain tumor-related epilepsy (btre) in a prospective, observational study.
PubMedID- 23289080 Relevant data regarding the seizure types of those with active epilepsy were found in 15 papers and were categorised based on the international league against epilepsy (ilae) classification of seizures .
PubMedID- 22172768 Conclusions: fine together with dtf was able to localize seizure onset zones of partial epilepsy patients.
PubMedID- 25485376 We propose a multispectral mri-based clinical decision support approach to carry out automated seizure focus lateralization in patients with temporal lobe epilepsy (tle).
PubMedID- 22957244 For example, forsgren and nystrom found that there was a seven-fold increase in rates of depression being diagnosed prior to the onset of the seizure disorder in patients with newly diagnosed epilepsy when compared to age- and sex-matched controls.
PubMedID- 21766042 Therefore, grafting of certain subclass of gaba-producing cells in a wrong location in some epilepsy types may lead to seizure exacerbation.
PubMedID- 25252007 Nonadherence is a major cause of seizure breakthrough in patients with epilepsy, particularly in young adults.
PubMedID- 21461679 We review recent work that assessed seizure remission in patients with intractable epilepsy during medical management.
PubMedID- 20888306 Depression in epilepsy is associated with lack of seizure control.
PubMedID- 25774191 Previous results have shown that parasympathetic activity decreases and sympathetic activity increases within 30 seconds prior to epileptic seizure in patients with temporal epilepsy, which suggests that epileptic seizures induce dysfunction of the cardiac autonomic nerve regulation center, thereby inducing sudden death.
PubMedID- 22380854 The rns trial examined closed-loop, responsive cortical stimulation of seizure foci in patients with refractory partial epilepsy, again finding significant reduction in seizure frequency.
PubMedID- PMC4036655 The in vivo pharmacoresistant models include the phenytoin-resistant kindled rat the lamotrigine-resistant kindled rat the 6 hz psychomotor seizure model of partial epilepsy , poststatus epileptic models of temporal lobe epilepsy and the methylazoxymethanol acetate in utero model of nodular heterotopias .
PubMedID- 23287426 Randomized placebo-controlled trials of adjunctive treatment have demonstrated that once-daily perampanel doses of 4-12mg/day significantly reduced partial-onset seizure frequency in patients with pharmacoresistant epilepsy along with a favorable tolerability profile.
PubMedID- 22723496 Purpose: to determine the ability of fully automated volumetric magnetic resonance (mr) imaging to depict hippocampal atrophy (ha) and to help correctly lateralize the seizure focus in patients with temporal lobe epilepsy (tle).
PubMedID- 22613010 Significant correlations were also found between anxiety symptoms and epilepsy-related variables, particularly with the seizure frequency and the number of currently taken anti-epileptic drugs.
PubMedID- 23428299 Overall results suggest that the neuropsychological endophenotypes in developmental adhd versus adhd in epilepsy differ with seizure-related variables predicting cognitive dysfunction.
PubMedID- 26230669 The indirect effects of age and seizure freedom, attributable to mediation through epilepsy severity, accounted for 25.0% and 30.3% of the total effects of these determinants on seizure-related disability, respectively.
PubMedID- 22808026 The increased γ corroborates with previous seizure-free network findings in patients with absence epilepsy and temporal neocortical epilepsy , where higher interictal γ was most pronounced in the eeg and meg delta bands.
PubMedID- 20124204 These findings support the concept that early epilepsy surgery is associated with seizure freedom in children with tsc and intractable epilepsy.
PubMedID- 20640459 Conclusions: apical temporal resection sparing the mesial temporal structures is an effective procedure with good long-term seizure outcome in patients with refractory epilepsy due to lesions confined to the apex of the temporal lobe.
PubMedID- 25317147 Gamma knife treatment for refractory epilepsy in seizure focus localized by positron emission tomography/ct.
PubMedID- 22957247 Using simultaneously scalp and intracranial recordings among patients with tle, intermittent rhythmic delta slowing was highly correlated with the irritative and seizure-onset zones in patients with neocortical temporal epilepsy but poorly correlated with the irritative seizure-onset zone in patients with mesial tle.
PubMedID- 22686598 Purpose: the long-term seizure outcome of juvenile myoclonic epilepsy (jme) is still controversial; the value of factors that are potentially predictive for seizure outcome remains unclear.
PubMedID- 26339958 Results all 6 patients identified carried diagnoses of intractable epilepsy with mixed seizure types.
PubMedID- 21189974 Reduced naa/cho ratios outside the epileptogenic region have been reported in temporal lobe epilepsy, and correlate with reductions in seizure-free outcomes after surgery30).
PubMedID- 23850575 These findings suggest that 3d-spier could be an improved diagnostic method for presurgical seizure localization in patients with intractable epilepsy and may also be useful for mapping normal brain function.
PubMedID- 24829909 Performed a study which evaluated and demonstrated the tolerability and safety of gabapentin when used as an adjunctive therapy in doses required to achieve the most effective seizure control in patients with epilepsy .
PubMedID- 21945365 seizure and eeg characteristics of patients with epilepsy and concomitant psychogenic non-epileptic seizures (pnes) were compared to age and sex matched controls with epilepsy alone in a retrospective case control study.
PubMedID- 22425715 Frontal lobe epilepsy with atypical seizure semiology resembling shuddering attacks or wet dog shake seizures.
PubMedID- 24801491 The authors found no relevant effect in terms of seizure frequency reduction in patients with frontal lobe epilepsy, whereas in patients with generalised epilepsy, mean reduction in seizure frequency was 77 %.
PubMedID- 23375964 We selected index dates for each control individual by randomly sampling the dates of first seizure in individuals with epilepsy from the same age group with the bsample command in stata.
PubMedID- 22544726 Theoretically it may be assumed that combining aeds with different mechanisms of action will provide a better potential for additive or even synergistic efficacy and/or a more favourable tolerability profile, and may also be more likely to be effective against a broad range of seizure types in patients with refractory epilepsy compared to combining aeds with the same mechanism of action .
PubMedID- 24806603 The key to the successful epilepsy surgery with complete postoperative seizure-free status is precise localization of the epileptic zone that must be resected and the adjacent eloquent areas of gray and white matter that must be preserved to avoid neurological defects.
PubMedID- 23216463 Conclusions: the presence of the transmantle sign in patients with medically refractory partial epilepsy is associated with highly favorable seizure control outcomes after surgical treatment.
PubMedID- 26235301 Long-lasting seizure-related anxiety in patients with temporal lobe epilepsy and comorbid psychiatric disorders.
PubMedID- 20976465 Twenty-five consecutive patients suffering from therapy resistant temporal lobe epilepsy with unilateral seizure onset who were evaluated for epilepsy surgery and agreed to undergo the additional special research imaging and spectroscopy protocol at 4 t were recruited between mid 2005 and the end of 2009 from the pacific epilepsy program, cpmc and the northern california comprehensive epilepsy center, ucsf.
PubMedID- 21292558 We describe the electroencephalographic and clinical seizure manifestations of pyridoxal 5'-phosphate-dependent epilepsy (plp-de) in two patients diagnosis confirmed by low cerebrospinal fluid (csf) plp, complete resolution of previously intractable seizures with plp supplementation, negative pyridoxine-dependent epilepsy csf biomarkers, and/or positive disease causing pyridox(am)ine 5'-phosphate oxidase gene mutation along with a comprehensive review of the literature.
PubMedID- 26370916 Association of adherence to epilepsy quality standards with seizure control.
PubMedID- 22369498 Background: the current report examines the risk of and predictors for developing epilepsy in children with febrile seizure (fs).
PubMedID- 20382841 Generalized epilepsy with febrile seizure plus (gefs+) is an autosomal dominant disorder.
PubMedID- 26146753 Objectives: the aim of this study was to analyze the impact of deep brain stimulation (dbs) of the posteromedial hypothalamus (phyp) on seizure frequency in patients with drug-resistant epilepsy (dre) associated with intractable aggressive behavior (iab).
PubMedID- 21112828 We report a video-eeg recording of a seizure in a patient with rolandic epilepsy which may be useful for educational purposes.
PubMedID- 24967871 In addition, our data suggest that cc could act in an allosteric site of gabaa, which would be different from the site in which bdz acts, since flumazenil was not able to reverse any of cc effects on the modulation of seizure parameters related with epilepsy models investigated.
PubMedID- 22380853 The majority of evidence supports vns usage in partial epilepsy with a seizure reduction of 50% or more in the majority of cases and freedom from seizure in 6%-27% of patients who responded to stimulation.
PubMedID- 26274319 Etx, a lower-potency non-selective t-type ca2+ channel blocker used clinically as an anti-seizure drug in patients with genetic generalized epilepsy, also demonstrated a trend towards delaying seizure severity in this model, but this was significantly less than that observed for z944.
PubMedID- 24977196 Although the accuracy is not very high, but with such a complex video dataset, the classification performance is satisfactory and can serve as a tool for automatically predicting the seizure status of the epilepsy patients.

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