PedAM
Pediatric Disease Annotations & Medicines
| Disease | neuropathy |
| Symptom | |pain |
| Sentences | 130 |
| PubMedID- 20188729 | Mutations of the neurotrophin receptor tyrosine kinase trka (ntrk1) cause congenital sensory neuropathy with insensitivity to pain and anhydrosis (cipa), also called hereditary sensory and autonomous neuropathy type iv (hsan iv). |
| PubMedID- 24529306 | Peripheral nervous system involvement includes small fiber neuropathy that is associated with neuropathic pain and autonomic dysfunction (reviewed in ). |
| PubMedID- 25024823 | pain associated with neuropathy is described in many presentations, such as the following; burning, electric-like, increased sensitivity to touch stimulation. |
| PubMedID- 19674790 | Peripheral neuropathy (pn), with neuropathic pain as main symptom, represents the dose-limiting toxicity of the proteasome inhibitor bortezomib. |
| PubMedID- 24009748 | This balance is severely impaired in neuropathy leading to enhanced pain sensations (hyperalgesia). |
| PubMedID- 20730020 | Altered pain perception and presence of autonomic neuropathy may modulate symptom expression. |
| PubMedID- 26140224 | Foot pain due to an entrapment neuropathy is not easy to diagnose and treat. |
| PubMedID- 20678683 | Adult subjects with refractory chronic pain because of diabetic neuropathy, postherpetic or trigeminal neuralgias, or cervical or lumbosacral radiculopathies were included. |
| PubMedID- 21676163 | Background: pregabalin and duloxetine are two fda-approved medications for the treatment of pain associated with diabetic peripheral neuropathy (pdpn). |
| PubMedID- 22704856 | Reported a patient who developed an acute neuropathy with pain as a prominent feature, evidence of demyelination on neurophysiology, who was found to have an arg36trp mutation in mpz 2. |
| PubMedID- 21091395 | Objective: to evaluate changes in healthcare resource use and costs after initiating pregabalin or duloxetine in employees with pain associated with diabetic peripheral neuropathy (pdpn). |
| PubMedID- 26439233 | Objective: current therapies for diabetic peripheral neuropathy with pain mask the painful symptoms while the underlying pathology continues to progress. |
| PubMedID- 23401682 | Because patients with diabetes are less sensitive to pain due to diabetic neuropathy, the pain associated with osteoporosis and the duration of arthralgia maybe more significant in this population. |
| PubMedID- 24424289 | Diabetic neuropathy is associated with neuropathic pain in about 50% of diabetic subjects. |
| PubMedID- 26311956 | Found that severity of carpal tunnel syndrome symptoms did not differ betweenneuropathic and non-neuropathic groups13).in our study, the number of cases in which neuropathic mechanisms could be the underlyingcause of pain due to ulnar neuropathy at the elbow was 10 (29.4%). |
| PubMedID- 23541708 | Background: in patients with chronic pain due to diabetic peripheral neuropathy (dpn) or postherpetic neuralgia (phn), pregabalin treatment results in pain relief and improved patient function/quality of life (qol). |
| PubMedID- 24983280 | Conclusion: this study showed the efficacy of venlafaxine, pregabalin, and carbamazepine in pain reduction in patients with diabetic neuropathy, although pregabalin was shown to be superior to carbamazepine, and venlafaxine in relieving pain, no significant superiority was shown between carbamazepine, and venlafaxine. |
| PubMedID- 20841612 | Objective: neuropathic pain due to small-fiber sensory neuropathy in type 2 diabetes can be diagnosed by skin biopsy with quantification of intra-epidermal nerve fiber (ienf) density. |
| PubMedID- 23279346 | We describe a 77-year-old woman with impaired glucose tolerance presenting with rapidly progressive axonal neuropathy leading to excruciating pain and severe weakness of lower limbs within 2 years from the onset. |
| PubMedID- 20103559 | These symptoms can be aggravated by a number of drugs including: vasodilators, diuretics, phenothiazines, insulin (through endothelium-dependent vasodilatation), and tricyclic antidepressants, a class of drugs commonly used for symptomatic relief of pain associated with painful diabetic neuropathy (19). |
| PubMedID- 21814323 | Hypothesized that thigh pain is due to obturator neuropathy caused by compression of the nerve or its roots between the psoas muscle and the stone. |
| PubMedID- 21693446 | The absence of pain due to neuropathy also masks the inflammatory reaction and makes a foreign body or severe osteomyelitis less obvious clinically. |
| PubMedID- 22189061 | pain hypersensitivity associated with peripheral neuropathy was attenuated by the tnfα antagonist etanercept . |
| PubMedID- 20236533 | In mice with established neuropathic pain due to diabetic peripheral neuropathy, neither intranasal/intraperitoneal cannabidiol nor sr144528 had any effect upon already present and chronic thermal hypersensitivity or tactile allodynia (figure 7). |
| PubMedID- 20842208 | A therapy that treats both the pain and neurodegeneration of diabetic neuropathy offers a viable route to regulatory approval and long-term benefit to patients. |
| PubMedID- 25556685 | Peripheral neuropathy can lead to neuropathic pain in a subset of patients. |
| PubMedID- 22923475 | Diabetic retinopathy (dr) and neuropathy are leading causes of blindness and pain in industrialized nations. |
| PubMedID- 25312934 | Available data indicate up to 33% incidence of pain in patients with neuropathy after bariatric surgery, resulting in significant decreases in quality of life and increases in health care costs. |
| PubMedID- 24121454 | Recently, the antidepressant drug venlafaxine, which is also used to manage pain associated with diabetic peripheral neuropathy, has been reported to significantly decrease the incidence of acute opn in a placebo-controlled, randomized, phase 3 trial; however, grade 1–2 vomiting was observed more frequently in patients who received venlafaxine . |
| PubMedID- 23111447 | Pharmacological therapies in type 1 diabetes for efficient control of glycemia and changes in pain alterations due to diabetic neuropathy are a continuous challenge. |
| PubMedID- 26426047 | Vc1.1 in the pnl and cci models, as well as observing analgesic efficacy of vc1.1 in pain associated with diabetic neuropathy (streptozotocin model) and inflammatory pain (at the highest doses only; complete freund’s adjuvant (cfa) model) (previously posted in the metabolic pharmaceuticals limited information sheet as cited in ). |
| PubMedID- 22454751 | Leprosy affects the peripheral nervous system causing mainly sensory poly-neuropathy with neuropathic pain and paresthesia in the first stage, and sensory loss with susceptibility to traumatic limb injuries in more advanced stages. |
| PubMedID- 22683276 | A length-dependent neuropathy with pain in the feet is a common complication of diabetes (painful diabetic neuropathy). |
| PubMedID- 23983777 | Gjg has been widely used to treat symptoms like numbness, vibration sensation, cold sensation, and limb pain associated with diabetic neuropathy . |
| PubMedID- 23439674 | 3 the evidence for use of nmda receptor antagonists (e.g., dextromethorphan and memantine) is also limited for pain due to diabetic neuropathy, postherpetic neuralgia, or other neuropathic pain conditions (e.g., phantom limb pain, peripheral nerve injury, and crps) (category c2 evidence). |
| PubMedID- 26413363 | Clinically, they may present with pain, swelling, restricted range of motion, neuropathy, vascular compromise, and abnormal cosmesis 5. |
| PubMedID- 24829909 | Investigated the effect of gabapentin monotherapy on pain associated with diabetic peripheral neuropathy by titrating from 900 to 3600 mg per day or maximum tolerated dosage or placebo . |
| PubMedID- 24403874 | Patients receiving haart develop a distal symmetric small fiber retrograde (‘dying back’) axonal neuropathy with pain . |
| PubMedID- 24260511 | Paclitaxel is known to induce sensory peripheral neuropathy with burning pain symptoms, allodynia, hyperalgesia tingling and numbness . |
| PubMedID- 23554750 | The symptoms of diabetic neuropathy include pain, numbness, tingling, or prickling that begins in the feet. |
| PubMedID- 24294303 | These include neuropathic pain associated with diabetic peripheral neuropathy, fibromyalgia, chronic low back pain, and osteoarthritis knee pain (oakp). |
| PubMedID- 24855395 | We have also safely treated patients on stable medication regimens for pain associated with peripheral neuropathy (eg, pregabalin, gabapentin) with carfilzomib. |
| PubMedID- 21075912 | Introduction: the pain associated with peripheral neuropathy (pn) observed in patients living with hiv/aids represents a difficult complication to manage. |
| PubMedID- 22745903 | Nearly 70 percent of those with diabetes have diabetic peripheral neuropathy, which can lead to severe neuropathic pain of the distal extremities. |
| PubMedID- 22761855 | Evidence has accumulated that abnormal hyperexcitability of nociceptive primary sensory neurons may contribute to the exaggerated pain associated with diabetic neuropathy , , . |
| PubMedID- 24015197 | Episodes of severe neuropathic pain or paresthesia due to small fiber neuropathy, premature strokes, and cerebral white matter lesions are common manifestations and generally appear early in the course of the disease. |
| PubMedID- 22248316 | The condition comprises a characteristic clinical syndrome of subacute optic neuropathy with prominent pain in which there is a clear and prompt response to treatment with systemic steroids but a relapse on steroid withdrawal 1. |
| PubMedID- 24753654 | All patients had pain associated with diabetic neuropathy for ≥6 months, and completed at least 1 daily pain diaries during screening phase and had a minimum average daily pain score of 4 on an 11-point (0–10) numerical rating scale (nrs). |
| PubMedID- 21479990 | The relationship between numbness, tingling, and shooting/burning pain in patients with chemotherapy-induced peripheral neuropathy (cipn) as measured by the eortc qlq-cipn20 instrument, n06ca. |
| PubMedID- 24494677 | This is despite the long-standing hypothesis that reduced ngf levels in the skin may be involved in the pathophysiology of neuropathic pain that is associated with diabetic neuropathy (anand, 2004). |