PedAM
Pediatric Disease Annotations & Medicines
| Disease | arteriosclerosis |
| Symptom | |stroke |
| Sentences | 79 |
| PubMedID- 26199315 | Patients were classified into stroke subtypes of large-artery atherosclerosis and small-vessel occlusion according to the trial of org 10172 in acute stroke treatment criteria.18 the primary outcome measure was all-cause mortality and the median follow-up time was 48 months. |
| PubMedID- 24203886 | The expression, processing and secretion of il-1 is normally tightly regulated and dysregulation of il-1 is thought to underlie the chronic progressive inflammation that results in atherosclerosis (leading to stroke and myocardial infarction), type 2 diabetes and osteoarthritis. |
| PubMedID- 23501976 | Methods and results: the trial to assess the effects of sch 530348 in preventing heart attack and stroke in patients with atherosclerosis (tra2 degrees p-timi 50) was a randomized, double-blind, placebo-controlled trial of vorapaxar in 26 449 patients with stable atherosclerotic vascular disease (myocardial infarction, stroke, or peripheral artery disease). |
| PubMedID- 26508980 | More evidences have shown that systemic inflammation can accelerate the progression of atherosclerosis and thrombosis with resulting ischemic stroke 6. |
| PubMedID- 21960567 | stroke outcomes and neuroimaging of intracranial atherosclerosis (sonia) criteria were used for identification of >/=50% stenosis. |
| PubMedID- 22133999 | stroke due to large-artery atherosclerosis (p = 0.025), current smoking (p = 0.008), history of smoking (p < 0.001), coronary artery disease (p = 0.0015) and peripheral artery disease (p = 0.024) was significantly more common in men than in women. |
| PubMedID- 24452610 | In trial to assess the effects of sch 530348 in preventing heart attack and stroke in patients with atherosclerosis (tra 2 degrees p-timi 50), the addition of vorapaxar reduced recurrent events compared with standard care in stable patients with prior myocardial infarction. |
| PubMedID- 20948205 | Methods: the study included 94 consecutive acute stroke patients with large-artery atherosclerosis associated with extracranial carotid stenosis. |
| PubMedID- 23789967 | Death typically occurs as a result of heart failure or stroke, with accompanying atherosclerosis and other cardiovascular disorders at about age 13 . |
| PubMedID- 23740690 | Accumulation of cholesterol esters in arteries is tightly linked to atherosclerosis and can lead to myocardial infarction, stroke, or sudden cardiac death. |
| PubMedID- 21063781 | Incidence of subclinical coronary atherosclerosis in patients with suspected embolic stroke using cardiac computed tomography. |
| PubMedID- 24021686 | However, the association of alp/phosphate with cerebral atherosclerosis and prognosis in patients with acute stroke is not well known. |
| PubMedID- 23306324 | Although risk factors and manifestation of atherosclerosis are commonly associated with stroke in the elderly, recent data suggests different causes for stroke in the young. |
| PubMedID- 21804776 | The etiology of ischemic stroke is mainly due to large artery atherosclerosis, from cardiac sources of embolism in approximately 30% of cases and small vessel disease leading to lacunar infarction, but a significant number of cases remain undetermined after a diagnostic approach 7. |
| PubMedID- 21375762 | The secondary outcomes will be fatal or non-fatal cardiovascular events: myocardial infarction, stroke, heart failure, evidence of new sub-clinical atherosclerosis, and sudden death. |
| PubMedID- 25370590 | Methods: consecutive patients with recent acute anterior circulation ischemic stroke because of large artery atherosclerosis were included in the study. |
| PubMedID- 20880493 | There were differences in genotype frequencies between stroke patients with atherosclerosis and controls (p=0.03), and in allele frequencies between diabetic patients and controls (p=0.04). |
| PubMedID- 25813797 | This article reviews this new class of antiplatelet therapy in detail with an acute focus on the tracer (thrombin receptor antagonist for clinical event reduction in acute coronary syndrome) and tra 2 degrees p-timi 50 (trial to assess the effects of vorapaxar in preventing heart attack and stroke in patients with atherosclerosis-thrombolysis in myocardial infarction 50) trials. |
| PubMedID- 22347666 | Two large-scale phase iii trials were conducted to evaluate the safety and efficacy of vorapaxar, the trial to assess the effects of vorapaxar in preventing heart attack and stroke in patients with atherosclerosis (tra-2p) in atherosclerosis patients and the trial to assess the effects of vorapaxar in preventing heart attack and stroke in patients with acs (tracer) in acs patients. |
| PubMedID- 23380846 | stroke prevention includes treatment of carotid atherosclerosis, the most common underlying cause of stroke, according to a specific diagnostic algorithm. |
| PubMedID- 25628741 | Hypercholesterolemia is closely associated with an increased risk of cardiovascular disease, including stroke, due to atherosclerosis of blood vessels. |
| PubMedID- 24302997 | Recently, a larger study performed in 189 patients with symptomatic icas in the stroke outcomes and neuroimaging of intracranial atherosclerosis (sonia) trial found that a sir <0.9 was independently related to recurrent stroke in the territory of the symptomatic artery (hazard ratio 10.9; 95% ci 2.0–58.9; p = 0.001) . |
| PubMedID- 24048247 | In these disorders, death most often occurs as a consequence of atherosclerosis, leading to stroke, ischemia, myocardial infarction, heart failure and other syndromes characterized by severely dysregulated inflammatory processes and their resulting degradation of tissue function . |
| PubMedID- 25977470 | Although data are limited, with regard to pharmacological interventions in cli patients, most of the pharmacological measures are of proven benefit in reducing the risk of death, myocardial infarction, heart failure, and stroke in patients with atherosclerosis, and therefore the use of such therapy, despite the lack of evidence in the setting of cli, is justified to limit adverse cardiovascular events.76–82 various reports have demonstrated that the use of “cardioprotective” medications such as statins, angiotensin-converting enzyme inhibitors and angiotensin receptor blockers, and antiplatelet agents is associated with a decreased cardiovascular event rate in patients with pad.77 however, little is known about the effectiveness of these drugs in patients with cli. |
| PubMedID- 22315705 | However, careful review of these studies, as well as long-term natural history observations for many decades, shows that carotid stenosis is much more sensitive as marker of systemic atherosclerosis than a cause of stroke . |
| PubMedID- 21437932 | Objective: stroke risk due to intracranial atherosclerosis increases with degree of arterial stenosis. |
| PubMedID- 21636778 | In addition, gene expression profiles have been developed that distinguish stroke due to large-vessel atherosclerosis from cardioembolic stroke. |
| PubMedID- 26060804 | Moreover, because progressive cerebral atherosclerosis is associated with a poor stroke outcome,32 our finding relative to the association between ω3-pufas and stroke prognosis may be valid. |
| PubMedID- 26251284 | This statement is supported by the fact that none of the individuals with the smallest average diameters had a stroke due to large intracranial atherosclerosis but rather cardioembolism (data not shown). |
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