PedAM
Pediatric Disease Annotations & Medicines
| Disease | arteriosclerosis |
| Symptom | |stroke |
| Sentences | 79 |
| PubMedID- 25071710 | Furthermore, stroke patients with intracranial atherosclerosis (icas) have higher recurrence rate of cerebral ischemia and death than those without icas. |
| PubMedID- 26312946 | Carotid endarterectomy (cea) is a common and efficacious surgical procedure for the prevention of ischemic stroke due to atherosclerosis of the internal carotid artery (ica). |
| PubMedID- 24167723 | Hypertension contributes to atherosclerosis, but with regard to stroke, the main effect of high blood pressure per se is that it directly causes strokes due to small vessel disease. |
| PubMedID- 21669115 | Methods: ninety-nine acute ischemic stroke patients, associated with large artery atherosclerosis, were divided into two groups based on the presence or absence of human cytomegalovirus immunoglobulin m (igm) (human cytomegalovirus-igm-positive/human cytomegalovirus-igm-negative = 33:66). |
| PubMedID- 24701213 | In fact, inflammation, together with endothelial dysfunction, played key roles in the initiation and progression of atherosclerosis leading to stroke, myocardial infarction, and other thrombo-occlusive diseases . |
| PubMedID- 23776627 | Specifically, people with diabetes suffer from accelerated, severe atherosclerosis, which then leads to heart attack, stroke, and peripheral vascular disease . |
| PubMedID- 23512577 | Apart from atherosclerosis, the major causes of ischemic stroke are supraventricular arrhythmias such as atrial fibrillation or atrial flutter. |
| PubMedID- 25465417 | Methods: the tra 2 degrees p-timi 50 (trial to assess the effects of vorapaxar in preventing heart attack and stroke in patients with atherosclerosis-thrombolysis in myocardial infarction 50) was a randomized, double-blind, placebo-controlled trial of vorapaxar 2.5 mg daily in 26,449 patients with atherosclerosis, stratified by qualifying disease (mi, pad, or cvd). |
| PubMedID- 24137198 | The risk of stroke increased in patients with severe aortic atherosclerosis, and the highest risk was observed in patients with plaques of ≥4 mm thickness. |
| PubMedID- 25750539 | In stroke patients with defined large-artery atherosclerosis or small-vessel disease, risk factors should be modified and antiplatelet drugs are recommended, along with carotid endarterectomy or percutaneous transluminal angioplasty in selected patients. |
| PubMedID- 24237608 | Interestingly, our data showed that the expression pattern of circulating let-7b in ischemic stroke patients with large-vessel atherosclerosis were different from patients with other subtypes. |
| PubMedID- 24324946 | In the recent multicenter study on the prevalence and outcomes of intracranial large artery atherosclerosis among patients with stroke and transient ischemic attack in china (the chinese intracranial atherosclerosis study), the prevalence of intracranial stenosis was 46.6% (1,335 patients, including 261 with coexisting extracranial carotid stenosis).22 in addition, geographic and sex differences were noted in the distribution of symptomatic intracranial atherosclerosis cases in china. |
| PubMedID- 23056917 | Recent studies , documenting significantly greater carotid artery intima-media thickening in patients with ischemic stroke due to large-artery atherosclerosis in comparison to patients with lacunar infarction, concur the former hypothesis. |
| PubMedID- 25922803 | In the trial to assess the effects of vorapaxar in preventing heart attack and stroke in patients with atherosclerosis-timi 50 (tra 2p-timi 50) trial (n=26,449) , secondary prevention by adjunctive vorapaxar (2.5 mg daily) versus placebo in addition to standard-of-care therapy (58% on dapt) was assessed among patients with known atherothrombotic disease (a history of mi, ischemic stroke, or peripheral arterial disease). |
| PubMedID- 26346960 | The trial to assess the effects of vorapaxar in preventing heart attack and stroke in patients with atherosclerosis-thrombolysis in myocardial infarction 50 (tra 2 degrees p-timi 50) investigated atherothrombotic events in patients with stable atherosclerosis. |
| PubMedID- 24127415 | atherosclerosis, the underlying cause of myocardial infarction, stroke and peripheral vascular disease, is the major cause of morbidity and mortality in the developed world. |
| PubMedID- 24312492 | The result suggested that roaf might modify stroke risk in patients with concurrent severe atherosclerosis of the intra- and extracranial cerebrovascular vessels. |
| PubMedID- 25388414 | Methods: this study included 10 550 participants (81.3% men, mean age 43 years) from a health screening program, in whom transcranial doppler ultrasonography was used to detect >50% intracranial stenosis based on criteria modified from the stroke outcomes and neuroimaging of intracranial atherosclerosis trial. |
| PubMedID- 25633540 | Furthermore, a stroke etiology of large artery atherosclerosis or cardioaortic embolism was significantly related to higher icac burden (p = 0.006). |
| PubMedID- 25183559 | Methods: a total of 373 ischemic stroke patients with large artery atherosclerosis were recruited and followed up. |
| PubMedID- 24940449 | This study aimed to investigate the possible mechanisms of ischemic stroke in patients with intracranial atherosclerosis using hrmri. |
| PubMedID- 20537496 | Ischemic stroke patients with carotid atherosclerosis (n = 54) had a worse overall cardiovascular dietary score than those without (n = 68): -2.2 +/- 4.4 vs -0.2 +/- 5.2; p = .024. |
| PubMedID- 24715897 | Compared with other subtypes, patients with stroke due to large artery atherosclerosis had the highest odds of recurrence at 7, 30 days, and 3 months (or = 2.9-3.3) for stroke recurrence at 30 days for small vessel stroke (or = 0.2) . |
| PubMedID- 26071659 | Objective: carotid intima-media thickness (cimt) and carotid plaque (cp) are proposed biomarkers of subclinical atherosclerosis associated with stroke risk. |
| PubMedID- 21889761 | Comparison of frequencies of patent foramen ovale and thoracic aortic atherosclerosis in patients with cryptogenic ischemic stroke undergoing transesophageal echocardiography. |
| PubMedID- 20733302 | Methods: in a case-control design, 1,669 patients with ischemic stroke due to large-artery atherosclerosis, cardioembolism or cerebral microangiopathy were genotyped for 4 haplotype tagging snps (rs3093075, rs1205, rs1130864 and rs1800947) in the crp gene which have been shown to influence crp serum concentrations. |
| PubMedID- 21822469 | Transesophageal echocardiography has also provided evidence that the aortic arch is a common source of embolic material, but the risk of cerebral embolism appears to be directly related to the size of atherosclerotic plaques visualized 2, so we have considered stroke due to atherosclerosis in this entity. |
| PubMedID- 23425777 | Or stroke could be due to accelerated atherosclerosis and hypertension, which in turn could be due to either accelerated aging, genetic/environmental factors or both. |
| PubMedID- 25337084 | Background: the stroke outcomes and neuroimaging of intracranial atherosclerosis (sonia) study validated noninvasive imaging tests of intracranial atherosclerosis against catheter angiography in a prospective, blinded, multicenter setting. |
| PubMedID- 21164133 | Background and purpose: understanding associations of carotid atherosclerosis with stroke subtypes may contribute to more effective prevention of stroke. |
| PubMedID- 21606455 | In addition, when compared with nondiabetic patients, those with t1d more frequently had coronary heart disease and peripheral arterial disease (pad) and those with t2d more often had obesity, pad, history of tia, and stroke attributable to large-artery atherosclerosis, and t2d patients were also more likely to be older and male than were the nondiabetic patients. |
| PubMedID- 24701425 | demonstrated threefold higher risk of ischemic stroke than those without carotid artery atherosclerosis, despite adjustment for traditional risk factors in patients with normal blood pressure (140/90 mm hg) but with carotid artery atherosclerosis (defined as cimt ≥ 0.81mm) and/or presence of plaque (cimt more than 1.2 mm) over a mean of 10.7 years. |
| PubMedID- 21264472 | In addition, evidence has accumulated that tia or mild-stroke patients with a large-artery atherosclerosis have a particularly high risk of early recurrent stroke, which reaches up to 28% within 14 days . |
| PubMedID- 22286013 | However, association between coronary and cerebral artery atherosclerosis in stroke patients has not fully been investigated. |
| PubMedID- 20738445 | Sch 530348 is currently evaluated in the randomized placebo-controlled phase iii trial to assess the effects of sch 530348 in preventing heart attack and stroke in patients with atherosclerosis (tra 2°p-timi) 50 trial. |
| PubMedID- 23573226 | Considering the high frequency of cerebral symptoms and hospitalization and poor prognosis of atherosclerotic stroke, patients with carotid atherosclerosis need to be followed up closely, especially those with caga+ hp infection. |
| PubMedID- 23736133 | Aha guidelines recommend using a statin to reduce the risk of recurrent stroke in patients with evidence of atherosclerosis, an ldl-c level > 100 mg/dl, and those who are without known coronary heart disease.50 maximum benefit is attained with a reduction of the ldl-c level by at least 50% or below 70 mg/dl. |
| PubMedID- 21547091 | Thus, homeobox genes could be used as disease markers or potential therapeutic targets of diseases, such as cancer, diabetic wound healing, lymphedema, alzheimer's disease, and stroke due to atherosclerosis . |
| PubMedID- 25529343 | Methods: we enrolled 76 korean patients with acute ischemic stroke due to large artery atherosclerosis who were treated with clopidogrel. |
| PubMedID- 25394855 | Results from this trial will provide important information on the merit of adding cilostazol to aspirin for slowing down progression of atherosclerosis in patients with ischemic stroke and pad. |
| PubMedID- 21311375 | Indications included acute stroke, treatment of intracranial atherosclerosis, vasospasm therapy, arteriovenous malformation embolization, and aneurysm embolization. |
| PubMedID- 25465416 | Methods: tra 2 degrees p-timi 50 (trial to assess the effects of vorapaxar in preventing heart attack and stroke in patients with atherosclerosis-thrombolysis in myocardial infarction 50) was a multinational, randomized, double-blind, placebo-controlled trial of vorapaxar in stable patients with prior myocardial infarction, peripheral arterial disease, or stroke. |
| PubMedID- 23065249 | atherosclerosis, a major cause of ischemic stroke, may be associated with variability of triglyceride (tg) levels. |
| PubMedID- 25426304 | The cerebral arteries may be uniquely susceptible to the atherosclerotic effects of smoking, such that it has a different risk profile for stroke compared with other atherosclerosis risk factors. |
| PubMedID- 24231460 | We detected stroke due to large-artery atherosclerosis in 493 patients, cardioembolism in 425, small-vessel occlusion in 583 and other aetiologies (stroke of other or undetermined aetiology) in 583 among the 2084 consecutive patients. |
| PubMedID- 21772967 | The stroke outcomes and neuroimaging of intracranial atherosclerosis (sonia) trial showed that both tcd and mra identify 50% to 99% intracranial large vessel stenosis with a significant negative predictive value. |
| PubMedID- 22297442 | Hutchinson-gilford progeria syndrome (hgps) is an autosomal dominant condition which develops in the first or second year of life, followed by severe and rapid premature senescence, which involves almost all tissues.1,2 patients present delayed growth, short stature, alopecia, thinning of skin, loss of subcutaneous fat, midface hypoplasia, skeletal involvement with osteolysis and fractures, premature atherosclerosis, cardiac failure leading to death or stroke at about 13.5 years. |
| PubMedID- 21347225 | The pathogenesis of ischemic stroke due to carotid atherosclerosis can be ascribed to cerebral embolism from carotid plaque and/or hypoperfusion due to stenosis 1. |
| PubMedID- 21349192 | The secondary outcomes will be fatal or non-fatal cardiovascular events: myocardial infarction, stroke, heart failure, evidence of new subclinical atherosclerosis and sudden death. |
| PubMedID- 25876749 | Cardiovascular events such as myocardial infarction (mi) and stroke due to enhanced inflammatory atherosclerosis account for increased premature mortality in rheumatoid arthritis (ra). |
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