PedAM
Pediatric Disease Annotations & Medicines
| Disease | wernicke-korsakoff syndrome |
| Phenotype | C0039841|thiamine deficiency |
| Sentences | 3 |
| PubMedID- 25695433 | thiamine deficiency is associated with wernicke-korsakoff syndrome, alzheimer’s disease, amyotrophic lateral sclerosis, parkinson’s disease, multiple sclerosis and diabetes [16,17], which are treated with effectiveness with thiamine or its derivatives. |
| PubMedID- 25206494 | It is believed that chronic alcohol use can damage the brain by inducing malnutrition and thiamine deficiency leading to wernicke-korsakoff syndrome. |
| PubMedID- 25446352 | Using the pyrithiamine-induced thiamine deficiency (ptd) rat model of human wernicke-korsakoff syndrome, we tested the hypothesis that co-infusion of the acetylcholinesterase inhibitor physostigmine across the pfc and hpc would recover spatial alternation performance in ptd rats. |
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