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PedAM

Pediatric Disease Annotations & Medicines




Disease wegener granulomatosis
Phenotype C0003864|arthritis
Sentences 3
PubMedID- 23115803 Rituximab is a chimeric murine/human monoclonal antibody (mab) that targets the cd20 antigen (also known as membrane-spanning 4-domains, subfamily a, member 1, or ms4a1) and has been approved by the united states food and drug administration for the treatment of non-hodgkins lymphomas (nhl; diffused large-b cell, low-grade, or follicular types), rheumatoid arthritis, granulomatosis with polyangiitis (wegener's granulomatosis) and microscopic polyangiitis.
PubMedID- 23115808 Rituximab is a chimeric murine/human monoclonal antibody (mab) that targets the cd20 antigen (also known as membrane-spanning 4-domains, subfamily a, member 1; or ms4a1), which is expressed on 95% of the transformed b-cells that participate in the pathogenesis of non-hodgkin lymphomas (nhl; diffused large-b cell, low-grade, or the follicular types), a hematological malignancy, and autoimmune diseases such as rheumatoid arthritis (ra), granulomatosis with polyangiitis (wegener's granulomatosis), and microscopic polyangiitis.
PubMedID- 23384023 A very rare case of etanercept-induced wegener's granulomatosis in a patient with long-standing rheumatoid arthritis is reported.

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