PedAM
Pediatric Disease Annotations & Medicines
| Disease | von willebrand disease |
| Phenotype | C0040053|thrombus |
| Sentences | 3 |
| PubMedID- 23878808 | An increased aggregation response to low-dose ristocetin (a type iib von willebrand disease-like defect) is associated with thrombus formation. |
| PubMedID- 23641007 | Hyperglycemia alters platelet ca2+ homeostasis leading to cytoskeleton abnormalities and increased secretion of proaggregant factors.58 moreover, up-regulation of glycoproteins ib and iib/iiia in diabetic patients triggers thrombus via interacting with von willebrand factor (vwf) and fibrin molecules (figure 4). |
| PubMedID- 23983474 | The circulating levels of d-dimers, plasminogen activator inhibitor-1, and von willebrand factor increase with thrombus formation. |
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