PedAM
Pediatric Disease Annotations & Medicines
| Disease | von willebrand disease |
| Phenotype | C0003507|aortic stenosis |
| Sentences | 3 |
| PubMedID- 26269004 | Unexpectedly high prevalence of acquired von willebrand syndrome in patients with severe aortic stenosis as evaluated with a novel large multimer index. |
| PubMedID- 21561895 | Increased thrombin generation and platelet activation are associated with deficiency in high molecular weight multimers of von willebrand factor in patients with moderate-to-severe aortic stenosis. |
| PubMedID- 20835786 | Similar to acquired von willebrand's disease seen in patients with aortic stenosis, the shear stress of the cf-lvad may cause proteolysis of the hmw multimers of vwf. |
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