PedAM
Pediatric Disease Annotations & Medicines
| Disease | vitamin b12 deficiency |
| Phenotype | C0002871|anemia |
| Sentences | 25 |
| PubMedID- 23565429 | Six patients (10%) had megaloblastic anemia with vitamin b12 deficiency including 3 cases of pernicious anemia. |
| PubMedID- 23028239 | Pernicious anemia represents 20%-50% of the causes of vitamin b12 deficiency in adults. |
| PubMedID- 23970962 | Among both male and female adolescents anemia with vitamin b12 deficiency was observed to be a significant public health problem. |
| PubMedID- 23964320 | Higher circulating concentrations of folate have been hypothesized to mask pernicious anemia due to vitamin b12 deficiency, cause cognitive impairment in elderly subjects, reduce the efficacy of anti-folate drugs, increase the risk of insulin resistance and obesity in children and have the potential to promote cancer [15-18]. |
| PubMedID- 21189935 | Peripheral blood macroovalocytosis, frequently found in cases of vitamin b12 deficiency associated with megaloblastic anemia, was masked because of the countervailing tendency of iron deficiency to produce hypochromic microcytic erythrocytes. |
| PubMedID- 23898268 | Hyperpigmentation of the skin with megaloblastic anemia associated with vitamin b12 deficiency was first observed by cook in 1944 [9, 10, 11]. |
| PubMedID- 22242613 | In spain, germany, and italy, the corresponding numbers would range from 100,000 to 200,000. in the usa, it has been estimated earlier that approximately 800,000 elderly people have undiagnosed and untreated pernicious anemia due to vitamin b12 deficiency [35]. |
| PubMedID- 24145274 | Pernicious anemia leading to vitamin b12 deficiency is another rare associated cause. |
| PubMedID- 23622894 | [prevalence of vitamin b12 deficiency in patients with iron-deficiency anemia referred for evaluation in internal medicine]. |
| PubMedID- 25918651 | In addition to clinical symptoms and laboratory data typical of cad, both patients had megaloblastic anemia due to vitamin b12 deficiency. |
| PubMedID- 25674111 | Pa is macrocytic anemia due to vitamin b12 deficiency as a result of deficiency of intrinsic factor because of the atrophy of gastric mucosa, and thus, the loss of parietal cells.9 varying incidence rates of pa have been reported.10,11 the present study evaluated the incidence of pa in patients with macrocytic anemia and in patients with low serum b12. |
| PubMedID- 21801350 | This suggests that there was no marked vitamin b12 deficiency, which can lead to megaloblastic anemia in individuals infected with fish tapeworm. |
| PubMedID- 22726312 | This case also highlights the need to consider vitamin b12 deficiency in infants with severe anemia even if their hematological parameters do not indicate megaloblastic anemia because the concomitant presence of substantial iron deficiency may modify the characteristics of the anemia. |
| PubMedID- 24353710 | Megaloblastic anemia due to vitamin b12 deficiency is well recognizable cause of pancytopenia. |
| PubMedID- 26080453 | Oral vitamin b12 is underused, and can be as effective as intramuscular vitamin b12 in managing anemia due to vitamin b12 deficiency. |
| PubMedID- 21174235 | Silent initially, the gastric lesion becomes manifest in humans by the development of megaloblastic pernicious anemia arising from vitamin b12 deficiency. |
| PubMedID- 24248213 | vitamin b12 deficiency may result from pernicious anemia, gastric resection, intestinal malabsorption or a strict vegan diet. |
| PubMedID- 22915983 | A synthetic dna problem is responsible for megaloblastic pernicious anemia, most often due to folate/vitamin b12 deficiency, poisonous toxins, or chemotherapeutic agents. |
| PubMedID- 26488490 | For children aged 12-35 months, multivariate logistic regression indicated that anemia was significantly associated with iron and vitamin b12 deficiency (or = 5.3; 95% ci: 1.9-14.5, p < 0.01) and monotonous diet (or = 2.3; 95% ci: 1.1-4.7, p < 0.05) after adjusting for age and gender. |
| PubMedID- 23415113 | This vitamin b12 deficiency is rarely associated with megaloblastic anemia [167]. |
| PubMedID- 25705682 | anemia due to vitamin b12 deficiency or anemia caused by folic acid deficiency was diagnosed when there were low serum levels of these vitamins in patients with anemia. |
| PubMedID- 23021957 | Case 2: a 14 month-old infant fed by a rice beverage for 2 months had iron and vitamin b12 deficiency with deep anemia (hb 35 g/l) and tissue hypoxia (hyperlactacidemia). |
| PubMedID- 26199768 | In both children and adults, vitamin b12 deficiency is associated with pancytopenia, megaloblastic anemia, splenomegaly, and retinopathy [8]. |
| PubMedID- 23984056 | The clinical presentation of vitamin b12 deficiency may be with anemia or with neurological symptoms, the latter of which is discussed in the following. |
| PubMedID- 25811010 | Nutritional deficiencies (especially vitamin b12 deficiency) as a cause of fever, hemolytic anemia, and thrombocytopenia are very rare and therefore rarely thought of. |
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